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https://www.readbyqxmd.com/read/29442612/a-review-of-a-decade-of-rugby-union-injury-epidemiology-2007-2017
#1
Pierre L Viviers, Jeandré T Viljoen, Wayne Derman
CONTEXT: Rugby union is the most widely played team collision sport globally. As with other contact sports, there is substantial risk of injury. To date, the majority of studies on injury epidemiology have focused on elite male cohorts, which inherently prevents extrapolation of research findings to other groups within the player continuum. This review aims to describe emerging injury trends across the spectrum of various rugby union subpopulations and to highlight gaps that may influence future injury prevention tactics...
February 1, 2018: Sports Health
https://www.readbyqxmd.com/read/29440947/psychological-stress-and-breast-cancer-incidence-a-systematic-review
#2
REVIEW
Valentina-Fineta Chiriac, Adriana Baban, Dan L Dumitrascu
Objective: Breast cancer is the world's leading cause of cancer mortality in women. Stress is an imminent risk factor with a documented negative impact on neuro-endocrine and immune system. Numerous epidemiological studies have investigated the link between stress and cancer, reporting contradictory results from no association to a close causal link. The impact of the topic and the lack of conclusion compelled this systematic review. Methods: A systematic review was carried out, including all literature studies from 1966 to 2016, investigating the relationship between stress and the occurrence of breast cancer...
2018: Clujul Medical (1957)
https://www.readbyqxmd.com/read/29438931/aggregating-the-response-in-time-series-regression-models-applied-to-weather-related-cardiovascular-mortality
#3
Pierre Masselot, Fateh Chebana, Diane Bélanger, André St-Hilaire, Belkacem Abdous, Pierre Gosselin, Taha B M J Ouarda
In environmental epidemiology studies, health response data (e.g. hospitalization or mortality) are often noisy because of hospital organization and other social factors. The noise in the data can hide the true signal related to the exposure. The signal can be unveiled by performing a temporal aggregation on health data and then using it as the response in regression analysis. From aggregated series, a general methodology is introduced to account for the particularities of an aggregated response in a regression setting...
February 9, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29438602/international-consensus-statement-on-allergy-and-rhinology-allergic-rhinitis
#4
Sarah K Wise, Sandra Y Lin, Elina Toskala, Richard R Orlandi, Cezmi A Akdis, Jeremiah A Alt, Antoine Azar, Fuad M Baroody, Claus Bachert, G Walter Canonica, Thomas Chacko, Cemal Cingi, Giorgio Ciprandi, Jacquelynne Corey, Linda S Cox, Peter Socrates Creticos, Adnan Custovic, Cecelia Damask, Adam DeConde, John M DelGaudio, Charles S Ebert, Jean Anderson Eloy, Carrie E Flanagan, Wytske J Fokkens, Christine Franzese, Jan Gosepath, Ashleigh Halderman, Robert G Hamilton, Hans Jürgen Hoffman, Jens M Hohlfeld, Steven M Houser, Peter H Hwang, Cristoforo Incorvaia, Deborah Jarvis, Ayesha N Khalid, Maritta Kilpeläinen, Todd T Kingdom, Helene Krouse, Desiree Larenas-Linnemann, Adrienne M Laury, Stella E Lee, Joshua M Levy, Amber U Luong, Bradley F Marple, Edward D McCoul, K Christopher McMains, Erik Melén, James W Mims, Gianna Moscato, Joaquim Mullol, Harold S Nelson, Monica Patadia, Ruby Pawankar, Oliver Pfaar, Michael P Platt, William Reisacher, Carmen Rondón, Luke Rudmik, Matthew Ryan, Joaquin Sastre, Rodney J Schlosser, Russell A Settipane, Hemant P Sharma, Aziz Sheikh, Timothy L Smith, Pongsakorn Tantilipikorn, Jody R Tversky, Maria C Veling, De Yun Wang, Marit Westman, Magnus Wickman, Mark Zacharek
BACKGROUND: Critical examination of the quality and validity of available allergic rhinitis (AR) literature is necessary to improve understanding and to appropriately translate this knowledge to clinical care of the AR patient. To evaluate the existing AR literature, international multidisciplinary experts with an interest in AR have produced the International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR). METHODS: Using previously described methodology, specific topics were developed relating to AR...
February 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29438600/international-consensus-statement-on-allergy-and-rhinology-allergic-rhinitis-executive-summary
#5
Sarah K Wise, Sandra Y Lin, Elina Toskala
BACKGROUND: The available allergic rhinitis (AR) literature continues to grow. Critical evaluation and understanding of this literature is important to appropriately utilize this knowledge in the care of AR patients. The International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR) has been produced as a multidisciplinary international effort. This Executive Summary highlights and summarizes the findings of the comprehensive ICAR:AR document. METHODS: The ICAR:AR document was produced using previously described methodology...
February 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29438495/collaborative-pooled-and-harmonized-study-designs-for-epidemiologic-research-challenges-and-opportunities
#6
Catherine R Lesko, Lisa P Jacobson, Keri N Althoff, Alison G Abraham, Stephen J Gange, Richard D Moore, Sharada Modur, Bryan Lau
Collaborative study designs (CSDs) that combine individual-level data from multiple independent contributing studies (ICSs) are becoming much more common due to their many advantages: increased statistical power through large sample sizes; increased ability to investigate effect heterogeneity due to diversity of participants; cost-efficiency through capitalizing on existing data; and ability to foster cooperative research and training of junior investigators. CSDs also present surmountable political, logistical and methodological challenges...
February 8, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29437866/how-to-use-sequence-analysis-for-life-course-epidemiology-an-example-on-hiv-positive-sub-saharan-migrants-in-france
#7
Anne Gosselin, Annabel Desgrées du Loû, Eva Lelièvre
BACKGROUND: Life course epidemiology is now an established field in social epidemiology; in sociodemography, the quantitative analysis of biographies recently experienced significant trend from event history analysis to sequence analysis. The purpose of this article is to introduce and adapt this methodology to a social epidemiology question, taking the example of the impact of HIV diagnosis on Sub-Saharan migrants' residential trajectories in the Paris region. METHODS: The sample consists of 640 migrants born in Sub-Saharan Africa receiving HIV care...
February 2, 2018: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29435969/-epidemiology-of-parkinson-s-disease-in-spain-and-its-contextualisation-in-the-world
#8
REVIEW
J Benito-Leon
INTRODUCTION: The study of the epidemiology of Parkinson's disease (PD) is essential because it is a public health problem and because the differences in its prevalence and incidence offer clues as to the existence of aetiologically important environmental or biological factors. AIMS: To report the most relevant data about the descriptive epidemiology (prevalence, incidence and mortality) of PD from studies conducted in different countries, with special emphasis on those carried out in Spain and Latin America...
February 16, 2018: Revista de Neurologia
https://www.readbyqxmd.com/read/29435958/understanding-the-relationship-between-food-variety-food-intake-and-energy-balance
#9
REVIEW
Hollie A Raynor, Maya Vadiveloo
PURPOSE OF REVIEW: In accordance with US dietary guidance, incorporating variety into the diet can align with energy balance, though greater food variety in some categories may make energy balance more challenging. Thus, experimental and epidemiologic evidence is summarized on the relationship between food variety, food and energy intake, and energy balance. RECENT FINDINGS: Lab-based, experimental research consistently demonstrates that greater variety within foods or sensory characteristics of food increases food and energy intake within an eating occasion...
February 13, 2018: Current Obesity Reports
https://www.readbyqxmd.com/read/29432583/the-clinical-utility-of-pgd-with-hla-matching-a-collaborative-multi-centre-eshre-study
#10
G Kakourou, S Kahraman, G C Ekmekci, H A Tac, G Kourlaba, E Kourkouni, A Cervero Sanz, J Martin, H Malmgren, C Giménez, V Gold, F Carvalho, C Billi, J F C Chow, X Vendrell, G Kokkali, J Liss, J Steffann, J Traeger-Synodinos
STUDY QUESTION: Has PGD-HLA been successful relative to diagnostic and clinical efficacy? SUMMARY ANSWER: The diagnostic efficacy of PGD-HLA protocols was found lower in this study in comparison to published PGD-HLA protocols and to that reported for general PGD by ESHRE (78.5 vs 94.1% and vs 92.6%, respectively), while the clinical efficacy has proven very difficult to assess due to inadequate follow-up of both the ART/PGD and HSCT procedure outcomes. WHAT IS KNOWN ALREADY: The first clinical cases for PGD-HLA were reported in 2001...
February 8, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29431523/molecular-diagnosis-of-antimicrobial-resistance-in-escherichia-coli
#11
Molly E Fleece, Suporn Pholwat, Amy J Mathers, Eric R Houpt
Antimicrobial resistance is a growing global public health threat. The complexities of antimicrobial resistance in gram-negative bacteria such as Escherichia coli pose significant diagnostic and therapeutic challenges. Molecular diagnostics are emerging in this field. Areas covered: The authors review the clinical importance of pathogenic E. coli and discuss the mechanisms of resistance to common antibiotics used to treat these infections. We review the literature on antimicrobial susceptibility testing and discuss the current state of phenotypic as well as molecular methodologies...
February 12, 2018: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/29430730/cerebral-ischemia-during-hemodialysis-finding-the-signal-in-the-noise
#12
EDITORIAL
Clare MacEwen, Peter Watkinson, Lionel Tarassenko, Christopher Pugh
Hemodialysis patients have multiple risk factors for small vessel cerebrovascular disease and cognitive dysfunction. Hemodialysis itself may cause clinically significant neurological injury through repetitive cerebral ischemia. However, supporting evidence to date consists of epidemiological associations, expert opinion, and small, single-centre studies of variable methodological quality. Isolating the impact of intra-dialytic hemodynamic instability from underlying renal and vascular disease on clinically relevant functional outcomes would require very large, controlled studies, given the heterogeneity and confounding comorbidities of the population, and the complex relationship between blood pressure and cerebral oxygen delivery...
February 11, 2018: Seminars in Dialysis
https://www.readbyqxmd.com/read/29423809/identification-of-driver-mutations-in-rare-cancers-the-role-of-smarca4-in-small-cell-carcinoma-of-the-ovary-hypercalcemic-type-sccoht
#13
Jessica D Lang, William P D Hendricks
Cancer is a complex genetic disease that can arise through the stepwise accumulation of mutations in oncogenes and tumor suppressor genes in a variety of different tissues. While the varied landscapes of mutations driving common cancer types such as lung, breast, and colorectal cancer have been comprehensively charted, the genetic underpinnings of many rare cancers remain poorly defined. Study of rare cancers faces unique methodological challenges, but collaborative enterprises that incorporate next generation sequencing, reach across disciplines (i...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29423807/physiologic-interpretation-of-gwas-signals-for-type-2-diabetes
#14
Richard M Watanabe
This chapter reviews both statistical and physiologic issues related to the pathophysiologic effects of genetic variation in the context of type 2 diabetes. The goal is to review current methodologies used to analyze disease-related quantitative traits for those who do not have extensive quantitative and physiologic background, as an attempt to bridge that gap. We leverage mathematical modeling to illustrate the strengths and weaknesses of different approaches and attempt to reinforce with real data analysis...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29421973/multimodal-characterization-of-the-late-effects-of-tbi-letbi-a-methodological-overview-of-the-letbi-project
#15
Brian L Edlow, C Dirk Keene, Daniel Perl, Diego Iacono, Rebecca Folkerth, William Stewart, Christine L MacDonald, Jean Augustinack, Ramon Diaz-Arrastia, Camilo Estrada, Elissa Flannery, Wayne Gordon, Tom Grabowski, Kelly Hansen, Jeanne Hoffman, Christopher Kroenke, Eric Larson, Patricia Lee, Azma Mareyam, Jennifer A McNab, Jeanne McPhee, Allison L Moreau, Anne Renz, KatieRose Richmire, Allison Stevens, Cheuk Y Tang, Lee S Tirrell, Emily Trittschuh, Andre van der Kouwe, Ani Varjabedian, Lawrence L Wald, Ona Wu, Anastasia Yendiki, Liza Young, Lilla Zollei, Bruce Fischl, Paul K Crane, Kristen Dams-O'Connor
Epidemiological studies suggest that a single moderate-to-severe traumatic brain injury (TBI) is associated with an increased risk of neurodegenerative disease, including Alzheimer's and Parkinson's disease (AD and PD). Histopathological studies describe complex neurodegenerative pathologies in individuals exposed to single moderate-to-severe TBI or repetitive mild TBI, including chronic traumatic encephalopathy (CTE). However, the clinicopathological links between TBI and post-traumatic neurodegenerative diseases such as AD, PD, and CTE remain poorly understood...
February 8, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29420641/when-are-pathogen-genome-sequences-informative-of-transmission-events
#16
Finlay Campbell, Camilla Strang, Neil Ferguson, Anne Cori, Thibaut Jombart
Recent years have seen the development of numerous methodologies for reconstructing transmission trees in infectious disease outbreaks from densely sampled whole genome sequence data. However, a fundamental and as of yet poorly addressed limitation of such approaches is the requirement for genetic diversity to arise on epidemiological timescales. Specifically, the position of infected individuals in a transmission tree can only be resolved by genetic data if mutations have accumulated between the sampled pathogen genomes...
February 8, 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29420239/depression-and-anxiety-symptoms-in-17-teams-of-female-football-players-including-10-german-first-league-teams
#17
Astrid Junge, Birgit Prinz
BACKGROUND: Information on the prevalence of mental health problems of elite athletes is inconclusive, most probably due to methodological limitations, such as low response rates, heterogeneous samples. AIMS: To evaluate the prevalence and risk factors of depression and anxiety symptoms in high-level female football players. METHODS: Female football players of 10 German first league (Bundesliga) and 7 lower league teams were asked to answer a questionnaire on players' characteristics, the Center of Epidemiologic Studies Depression Scale (CES-D) and the Generalised Anxiety Disorder (GAD-7) scale...
February 2, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29419641/epidemiology-of-exfoliation-syndrome
#18
Anastasios G P Konstas, Amund Ringvold
BACKGROUND: From a historical standpoint the epidemiology of exfoliation syndrome (XFS) is one of the most controversial subjects in ophthalmic literature. Current literature abounds with studies on the prevalence of XFS in various ethnic populations and clearly XFS is a common condition, but its true prevalence is difficult to ascertain. Overall, XFS is considered to be the most common identifiable cause of glaucoma worldwide. PURPOSE: This review critically examines the published literature documenting the epidemiological features of XFS and attempts to provide a unified concept concerning existing controversy...
February 6, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29419621/the-impact-of-transitional-care-programs-on-health-services-utilization-in-community-dwelling-older-adults-a-systematic-review
#19
Lori E Weeks, Marilyn Macdonald, Ruth Martin-Misener, Melissa Helwig, Andrea Bishop, Damilola F Iduye, Elaine Moody
OBJECTIVE: The objective was to identify and synthesize the best available evidence on the impact of transitional care programs on various forms of health services utilization in community-dwelling older adults. INTRODUCTION: There is growing evidence that transitional care programs can help address important challenges facing health care systems and our increasing older adult population in many countries by reducing unnecessary health service utilization. There is a need for a systematic review of the research evaluating the impact of transitional care programs on hospital and other health service usage...
February 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29412306/clinical-and-epidemiological-teaching-of-dengue-through-simulated-practice
#20
João Henrique de Morais Ribeiro, Eloá Otrenti, Renata Ferreira Takahashi, Lúcia Yasuko Izumi Nichiata, Maria Clara Padoveze, Érica Gomes Pereira, Sebastião Silveira Nunes Júnior, Anna Luiza de Fátima Pinho Lins Gryschek, Suely Itsuko Ciosak
OBJECTIVE: to describe the experience of clinical teaching on dengue and the practice of epidemiological surveillance using problematization methodology. METHOD: report of experience on educational activity with undergraduate nursing students, held in March 2016, at a public university in the city of São Paulo, conceived in four stages: dialogic lecture, active search of Aedes aegypti, case study and simulation of nursing consultation to individuals with dengue...
March 2018: Revista Brasileira de Enfermagem
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