Read by QxMD icon Read

Methodology, epidemiology

Emmanuelle Kesse-Guyot, Karen Assmann, Valentina Andreeva, Katia Castebon, Caroline Méjean, Mathilde Touvier, Benoît Salanave, Valérie Deschamps, Sandrine Péneau, Léopold Fezeu, Chantal Julia, Benjamin Allès, Pilar Galan, Serge Hercberg
BACKGROUND: Traditional epidemiological research methods exhibit limitations leading to high logistics, human, and financial burden. The continued development of innovative digital tools has the potential to overcome many of the existing methodological issues. Nonetheless, Web-based studies remain relatively uncommon, partly due to persistent concerns about validity and generalizability. OBJECTIVE: The objective of this viewpoint is to summarize findings from methodological studies carried out in the NutriNet-Santé study, a French Web-based cohort study...
October 18, 2016: JMIR Public Health and Surveillance
Jinho Shin
Arterial pulsation which had long been studied for estimation of blood pressure or mean blood pressure was replaced by the measurement of systolic and diastolic blood pressure using Korotkoff sound detected by stethoscope in the beginning of the previous century. In the meantime, vast of modern knowledge of human hypertension from epidemiology to randomized clinical trial had been built on the Korotkoff sound and stethoscope methodology. Hypertension is very special clinical entity in terms of the diagnosis is solely dependent on the manual blood pressure measurement by a physician or nurse...
September 2016: Journal of Hypertension
Rafael Hernandez-Hernandez
For the last three-decade cardiovascular disease have been the principal causes of death in most Latin American countries. Their importance has been rising, as in developed countries; such as United State, the mortality rate for CV disease declined in LA rises as in the other developing countries.Cardiovascular risk factors epidemiological studies from LA tend to be limited, and with restrictions on the methodology for sampling and interpretation of results; making most of the studies little comparable each other;on the other hand, population characteristics from country to country and inside each country are so different in ethnicity, habits, socio-economic status which make difficult to integrate and compare results as a whole...
September 2016: Journal of Hypertension
Garabed Eknoyan
Diseases of the kidney are old, but the discipline dedicated to their study, nephrology, is barely more than 50 years old. As recounted in this recollection of those events, the rudiments of what would become nephrology emerged in the time between the 2 World Wars from basic studies of normal kidney function and flourished after the integration of their methodologies into clinical medicine thereafter. Although shaped by studies of kidney function in the 1960s, it was the subsequent advent of dialysis that fueled the growth of nephrology well into the 21st century...
October 14, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Rui Quintas, Milda Cerniauskaite, Ambra Mara Giovannetti, Silvia Schiavolin, Alberto Raggi, Venusia Covelli, Flavio Villani, Giuseppe Didato, Francesco Deleo, Silvana Franceschetti, Simona Binelli, Laura Canafoglia, Marina Casazza, Matilde Leonardi
AIM: The aim of this observational study was to test the effectiveness of the PARADISE 24 instrument in describing the psychosocial difficulties (PSDs) reported by people with epilepsy, their relation with disability, and quality-of-life (QoL) levels and, overall, to explore a horizontal epidemiology methodology applied to a sample of patients with epilepsy. METHODS: A convenience sample of 80 adult patients with epilepsy was included in this cross-sectional study...
October 12, 2016: Epilepsy & Behavior: E&B
Hye-Yeon Kim, Jin-Woo Kim, Sun-Jong Kim, Sang-Hwa Lee, Hong-Soo Lee
To assess the relevance of previous epidemiologic studies on bisphosphonate-related osteonecrosis of the jaw (BRONJ), we first conducted a systematic review of large population-based observational studies, and evaluated the validity of claims-based algorithms for the identification of BRONJ. Studies containing primary observational epidemiologic data regarding bisphosphonate exposure and outcomes of osteonecrosis of the jaw were systematically reviewed. Using surrogates for identifying potential BRONJ cases from a population-based hospital registry, validation was performed through medical chart review...
October 13, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
Anne Spichler Moffarah, Mayar Al Mohajer, Bonnie L Hurwitz, David G Armstrong
The skin is colonized by a diverse collection of microorganisms which, for the most part, peacefully coexist with their hosts. Skin and soft tissue infections (SSTIs) encompass a variety of conditions; in immunocompromised hosts, SSTIs can be caused by diverse microorganisms-most commonly bacteria, but also fungi, viruses, mycobacteria, and protozoa. The diagnosis of SSTIs is difficult because they may commonly masquerade as other clinical syndromes or can be a manifestation of systemic disease. In immunocompromised hosts, SSTI poses a major diagnostic challenge, and clinical dermatological assessment should be initially performed; to better identify the pathogen and to lead to appropriate treatment, etiology should include cultures of lesions and blood, biopsy with histology, specific microbiological analysis with special stains, molecular techniques, and antigen-detection methodologies...
August 2016: Microbiology Spectrum
Aditi Roy, Katarzyna Kordas
Experimental studies in animals and observational studies in occupationally exposed adults indicate that higher lead exposure results in higher biomarkers of oxidative stress. However, this evidence cannot be extended to the general population who typically experience lower levels of lead exposure. This systematic review evaluates the epidemiological evidence on the association between lead and oxidative stress in non-occupationally exposed general population, with a particular focus on the pediatric population...
October 10, 2016: Current Environmental Health Reports
Carol S North
Worldwide, disasters are increasing in frequency and severity. Mental health consequences of disasters are extensive, and knowledge of anticipated mental health effects is needed for effective disaster response. Difficulties inherent in conducting disaster research have limited the understanding of research findings. This article presents and interprets disaster mental health research findings in the context of research methods. A brief history of the disaster mental health research field is provided, and the presentation of findings is ordered into topical areas of disaster mental health consequences and timing and prediction of mental health outcomes...
2016: Psychiatry
Felix Eckstein, Robert Buck, Wolfgang Wirth
OBJECTIVE: The metric accepted by regulatory bodies for determining structural progression in clinical trials of knee osteoarthritis (OA) remains change in radiographic joint space width in the medial femorotibial compartment. However, magnetic resonance imaging has revealed that cartilage loss is spatially heterogeneous, and that it is enigmatic which knee will lose cartilage at which location. Whereas previous reviews have focused on imaging in general, the purpose of this particular perspective is to highlight availability and applications of location-independent analysis methodology in measuring structural progression in epidemiological and interventional clinical trials, and to highlight its specific advantages over existing methodologies...
August 26, 2016: Seminars in Arthritis and Rheumatism
Marina B Klein, Jürgen K Rockstroh, Linda Wittkop
PURPOSE OF REVIEW: Hepatitis C virus (HCV) coinfection is a common and an important comorbidity in HIV infection. We review current trends in mortality and the potential for early combination antiretroviral therapy (cART) and HCV therapy to improve survival in coinfected patients. RECENT FINDINGS: HIV/HCV coinfection increases risk of death from all causes, and from liver disease and harmful drug use in particular. There is growing evidence for a direct role of HIV in liver fibrogenesis and for cART to decrease the risk of dying from liver disease in coinfected persons...
September 2016: Current Opinion in HIV and AIDS
Kostyantyn Dumchev, Olga Varetska, Ihor Kuzin
Once facing the most severe HIV epidemic in Eastern Europe, Ukraine has built an elaborate Monitoring and Evaluation (M&E) system to track the response to AIDS. This system was developed using recommendations and input from multiple international expert organizations and donors and, at the current stage, serves as a best practice model in many areas. The present paper aims to provide a comprehensive overview of the evolution of the M&E system in Ukraine since its inception. Notable achievements and challenges are described and illustrated by epidemiological data and the recommendations for future development are discussed...
October 6, 2016: AIDS and Behavior
Alessandro Tonacci, Lucia Billeci, Liliana Ruta, Gennaro Tartarisco, Giovanni Pioggia, Sebastiano Gangemi
BACKGROUND: Autism Spectrum Disorder represents a burdensome condition in early childhood, with a number of risk factors proposed to explain its pathogenesis, most of which without a reliable scientific basis. Allergic asthma is likely to be one of the possible comorbilities of autism. EVIDENCE ACQUISITION: In this paper, the relationship between autism and allergic asthma was analyzed through a systematic literature review, conducted according to the PRISMA guidelines...
October 5, 2016: Minerva Pediatrica
Ren-Nan Feng, Shan-Shan Du, Yang Chen, Zhen Li, Ying-Feng Zhang, Chang-Hao Sun, Yong-Shuai Jiang
BACKGROUND AND OBJECTIVES: National dietary surveys are needed and difficult to conduct in China. The current study aims to develop and validate an internet-based diet questionnaire for Chinese (IDQC) to assess intakes in Northern China. METHODS AND STUDY DESIGN: We recruited 292 city residents by email and telephone in Harbin to obtain the IDQC and 3-day diet diaries. The food group and nutrient intakes from the IDQC were validated against those from the 3-day diet diaries...
December 2016: Asia Pacific Journal of Clinical Nutrition
K C Koenen, J A Sumner, P Gilsanz, M M Glymour, A Ratanatharathorn, E B Rimm, A L Roberts, A Winning, L D Kubzansky
Post-traumatic stress disorder (PTSD) has been declared 'a life sentence' based on evidence that the disorder leads to a host of physical health problems. Some of the strongest empirical research - in terms of methodology and findings - has shown that PTSD predicts higher risk of cardiometabolic diseases, specifically cardiovascular disease (CVD) and type 2 diabetes (T2D). Despite mounting evidence, PTSD is not currently acknowledged as a risk factor by cardiovascular or endocrinological medicine. This view is unlikely to change absent compelling evidence that PTSD causally contributes to cardiometabolic disease...
October 4, 2016: Psychological Medicine
Aryna Zanuzdana, Karla Köpke, Walter Haas
Influenza and community-acquired pneumonia (CAP) impose a considerable annual burden on the German primary care system. Yet there is a lack of epidemiological data from the country's outpatient sector on groups at risk as well as on the complications of these diseases.The Robert Koch Institute (RKI) initiated the study to identify population groups at increased risk for influenza or CAP as well as related comorbidities and sequelae. We present the methodology of the study and the descriptive analysis of the patients...
September 30, 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Alex Magno Coelho Horimoto, Erica Naomi Naka Matos, Márcio Reis da Costa, Fernanda Takahashi, Marcelo Cruz Rezende, Letícia Barrios Kanomata, Elisangela Possebon Pradebon Locatelli, Leandro Tavares Finotti, Flávia Kamy Maciel Maegawa, Rosa Maria Ribeiro Rondon, Natália Pereira Machado, Flávia Midori Arakaki Ayres Tavares do Couto, Túlia Peixoto Alves de Figueiredo, Raphael Antonio Ovidio, Izaias Pereira da Costa
INTRODUCTION: Systemic sclerosis (SSc) is an autoimmune disease which shows extreme heterogeneity in its clinical presentation and that follows a variable and unpredictable course. Although some discrepancies in the incidence and prevalence rates between geographical regions may reflect methodological differences in the definition and verification of cases, they may also reflect true local differences. OBJECTIVES: To determine the prevalence and incidence of SSc in the city of Campo Grande, state capital of Mato Grosso do Sul (MS), Brazil, during the period from January to December 2014...
September 17, 2016: Revista Brasileira de Reumatologia
D Bailly
OBJECTIVE: If abstinence from substance in adolescents may nowadays be regarded statistically as a deviant behavior, what is its significance from a developmental point of view? The aim of this article is to examine the mental health characteristics and the social integration of adolescent abstainers. METHODS: A comprehensive literature review of epidemiological studies including data on adolescent abstainers was conducted. RESULTS: Compared to the abundant literature devoted to adolescent substance abusers, few studies report data on adolescent abstainers...
September 29, 2016: L'Encéphale
Diana F Florescu, Uriel Sandkovsky
Diarrhea is a common complication in solid organ transplant (SOT) recipients and may be attributed to immunosuppressive drugs or infectious organisms such as bacteria, viruses or parasites. Cryptosporidium usually causes self-limited diarrhea in immunocompetent hosts. Although it is estimated that cryptosporidium is involved in about 12% of cases of infectious diarrhea in developing countries and causes approximately 748000 cases each year in the United States, it is still an under recognized and important cause of infectious diarrhea in SOT recipients...
September 24, 2016: World Journal of Transplantation
M D Agh-Atabay, A Sofizadeh, G M Ozbaki, N Malaki-Ravasan, M R Ghanbari, O Mozafari
BACKGROUND & OBJECTIVES: Leishmaniasis is an endemic parasitic disease reported sporadically throughout Iran. Golestan province is one of the 17 zoonotic cutaneous leishmaniasis (ZCL) foci. In this study, ecoepidemiological characteristics of ZCL were investigated in Gonbad-e Kavus County, Golestan province of Iran. METHODS: This cross-sectional study was carried out in three endemic villages and one ZCL-free village by exploiting a stratified random sampling methodology in 2013...
July 2016: Journal of Vector Borne Diseases
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"