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https://www.readbyqxmd.com/read/28343151/gastric-outlet-obstruction-an-unusual-case-of-primary-duodenal-tuberculosis
#1
Sanket Kalpande, Jayashri Sanjay Pandya, Ajeet Tiwari, Devbrata Adhikari
BACKGROUND: Tuberculosis is a major health problem worldwide. Gastrointestinal tuberculosis presenting as isolated involvement of the duodenum is a rare case. CASE PRESENTATION: A 13 year male, presented with features of gastric outlet obstruction. CT enterography scan showed circumferential mural thickening in first and second part of duodenal junction causing luminal narrowing. Upper GI endoscopy confirmed the narrowing of D1-D2 junction. Duodenal biopsy showed duodenitis with negative result for AFB stain, Helicobacter Pylori...
March 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28334618/is-there-a-role-of-magnetic-resonance-imaging-in-deciding-to-stop-anti-tumor-necrosis-factor-treatment-in-ileal-crohn-s-disease
#2
Jose C Gallego, Ana Echarri
PURPOSE: This study was performed to assess the ability of magnetic resonance enterography to predict the evolution of patients in whom anti-tumor necrosis factor-α therapy was suspended. METHODS: A prospective study of patients with ileal Crohn's disease was performed. RESULTS: Twenty-nine patients were included. Patients who later relapsed showed higher magnetic resonance scores than those who did not relapse (4.2 vs. 2.5, respectively; p<0...
March 16, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28302273/there-is-good-agreement-between-mr-enterography-and-bowel-ultrasound-with-regards-to-disease-location-and-activity-in-paediatric-inflammatory-bowel-disease
#3
J L Barber, J Maclachlan, K Planche, M Furman, D Crespi, N Bab, I Beal
AIM: To investigate concordance of bowel ultrasound and magnetic resonance enterography (MRE) in identifying active disease in children with inflammatory bowel disease. MATERIALS AND METHODS: The imaging of children with inflammatory bowel disease who had undergone bowel ultrasound and MRE within 30 days were retrospectively reviewed, from January 2009 to November 2015. Ultrasound was without oral contrast medium; MRI was conducted with patients unsedated with oral contrast medium and gadolinium...
March 14, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28298964/magnetic-resonance-enterography-in-crohn-s-disease-how-we-do-it-and-common-imaging-findings
#4
REVIEW
Annalisa Mantarro, Paola Scalise, Elisa Guidi, Emanuele Neri
Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract, with unpredictable clinical course by phases of relapses alternating with other of quiescence. The etiology is multifactorial and is still not completely known; globally the westernization of lifestyle is causing an increasing incidence of CD, with peak age of 20-30 years. The diagnostic workup begins with the evaluation of the clinical history, physical examination and laboratory tests. However, the clinical assessment is subjected interobserver variability and, occasionally, the symptoms of acute and chronic inflammation may be indistinguishable...
February 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28298727/using-computed-tomography-enterography-to-evaluate-patients-with-crohn-s-disease-what-impact-does-examiner-experience-have-on-the-reproducibility-of-the-method
#5
Stênio Burlin, Larissa Rossini Favaro, Elisa Almeida Sathler Bretas, Lincoln Seiji Taniguchi, Ana Paula Loch, Marjorie Costa Argollo, Orlando Ambrogini Junior, Giuseppe D'Ippolito
OBJECTIVE: To assess the impact that examiner experience has on the reproducibility and accuracy of computed tomography (CT) enterography in the detection of radiological signs in patients with Crohn's disease. MATERIALS AND METHODS: This was a retrospective, cross-sectional observational study involving the analysis of CT enterography scans of 20 patients with Crohn's disease. The exams were analyzed independently by two radiologists in their last year of residence (duo I) and by two abdominal imaging specialists (duo II)...
January 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28292640/cross-sectional-evaluation-of-transmural-healing-in-patients-with-crohn-s-disease-on-maintenance-treatment-with-anti-tnf-alpha-agents
#6
Fabiana Castiglione, Pierpaolo Mainenti, Anna Testa, Nicola Imperatore, Giovanni Domenico De Palma, Matilde Rea, Olga Maria Nardone, Marco Sanges, Nicola Caporaso, Antonio Rispo
BACKGROUND: Transmural healing (TH) of Crohn's disease (CD) is a still unexplored and interesting outcome correlated to concept of deep remission. AIM: To assess the rate of TH in CD patients treated with anti-TNF alpha agents using two cross-sectional procedures: bowel sonography (BS) and magnetic resonance enterography (MRE). METHODS: We performed a 2-year observational longitudinal study, evaluating steroid-free clinical remission (CR), mucosal healing (MH), and TH in CD patients who would complete a 2-year treatment period with anti-TNFs...
February 28, 2017: Digestive and Liver Disease
https://www.readbyqxmd.com/read/28286879/dynamic-contrast-enhanced-magnetic-resonance-enterography-and-dynamic-contrast-enhanced-ultrasonography-in-crohn-s-disease-an-observational-comparison-study
#7
Rune Wilkens, David A Peters, Agnete H Nielsen, Valeriya P Hovgaard, Henning Glerup, Klaus Krogh
Purpose e Cross-sectional imaging methods are important for objective evaluationof small intestinal inflammationinCrohn'sdisease(CD).The primary aim was to compare relative parameters of intestinal perfusion between contrast-enhanced ultrasonography (CEUS) and dynamic contrast-enhanced magnetic resonance enterography (DCE-MRE) in CD. Furthermore, we aimed at testing the repeatability of regions of interest (ROIs) for CEUS. Methods This prospective study included 25 patients: 12 females (age: 37, range: 19-66) with moderate to severe CD and a bowel wall thickness>3mm evaluated with DCE-MRE and CEUS...
February 2017: Ultrasound International Open
https://www.readbyqxmd.com/read/28283726/magnetic-resonance-enterography-has-good-inter-rater-agreement-and-diagnostic-accuracy-for-detecting-inflammation-in-pediatric-crohn-disease
#8
Peter C Church, Mary-Louise C Greer, Ruth Cytter-Kuint, Andrea S Doria, Anne M Griffiths, Dan Turner, Thomas D Walters, Brian M Feldman
BACKGROUND: Magnetic resonance enterography (MRE) is increasingly relied upon for noninvasive assessment of intestinal inflammation in Crohn disease. However very few studies have examined the diagnostic accuracy of individual MRE signs in children. OBJECTIVE: We have created an MR-based multi-item measure of intestinal inflammation in children with Crohn disease - the Pediatric Inflammatory Crohn's MRE Index (PICMI). To inform item selection for this instrument, we explored the inter-rater agreement and diagnostic accuracy of individual MRE signs of inflammation in pediatric Crohn disease and compared our findings with the reference standards of the weighted Pediatric Crohn's Disease Activity Index (wPCDAI) and C-reactive protein (CRP)...
March 10, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28267043/a-fixed-stricture-on-routine-cross-sectional-imaging-predicts-disease-related-complications-and-adverse-outcomes-in-patients-with-crohn-s-disease
#9
Naueen A Chaudhry, Michael Riverso, Joseph R Grajo, Patricia P Moser, Fei Zou, Maher Homsi, Darashana R Punglia, Ellen M Zimmermann
BACKGROUND: Patients with Crohn's disease (CD) typically undergo multiple cross-sectional imaging exams including computed tomography and magnetic resonance enterography during the course of their disease. The aim was to identify imaging findings that predict future disease-related poor outcomes. METHODS: This was a retrospective, case control study at a single tertiary center. Cases were CD patients diagnosed with complications (bowel obstruction, perforation, internal fistula, or abscess); controls were CD patients without complications...
April 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28256148/accumulation-of-mesalazine-pills-in-the-medium-ileum-in-a-patient-with-crohn%C3%A2-s-disease
#10
Carmen Martínez Huertas, Paloma Garcia-Villanova Ruiz, José Pozo Sánchez, Cristina Dávila Arias
Crohn´s disease is an inflammatory disease that can involve any portion of the gastrointestinal tract, although terminal ileum is the most commonly affected portion. It is characterized by a transmural and discontinuous distribution pattern, with alternating periods of active disease and remission. We present the case of a 23-year-old patient diagnosed with Crohn´s disease, in treatment with extended release Mesalazine and corticoids. The CT Enterography showed activity signs and a great dilatation of medium ileum with lots of Mesalazine pills accumulated inside...
March 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28252210/clinical-endoscopic-and-radiographic-outcomes-with-ustekinumab-in-medically-refractory-crohn-s-disease-real-world-experience-from-a-multicentre-cohort
#11
C Ma, R N Fedorak, G G Kaplan, L A Dieleman, S M Devlin, N Stern, K I Kroeker, C H Seow, Y Leung, K L Novak, B P Halloran, V W Huang, K Wong, P K Blustein, S Ghosh, R Panaccione
BACKGROUND: Ustekinumab is a monoclonal antibody targeting interleukins-12 and -23, with efficacy in Crohn's disease (CD) demonstrated in clinical trials. AIM: To assess the real-world clinical, endoscopic and radiographic response and remission outcomes achieved with ustekinumab in medically-refractory CD. METHODS: A retrospective multicentre cohort study was performed on CD patients receiving ustekinumab between 2011 and 2016. The primary outcome was achievement of clinical and objective steroid-free response and remission at 3, 6 and 12 months...
March 2, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28225669/mr-enterography-assessment-of-bowel-inflammation-severity-in-crohn-disease-using-the-mr-index-of-activity-score-modifying-roles-of-dwi-and-effects-of-contrast-phases
#12
Jin Sil Kim, Hye Young Jang, Seong Ho Park, Kyung-Jo Kim, Kyunghwa Han, Suk-Kyun Yang, Byong Duk Ye, Sang Hyoung Park, Jong Seok Lee, Hyun Jin Kim
OBJECTIVE: The purpose of this article is to appraise the use of the MR index of activity (MaRIA) score in evaluating Crohn disease (CD) on present-day MR enterography images, with an emphasis on determining the modifying roles of DWI and the effects of different contrast enhancement phases. SUBJECTS AND METHODS: Fifty patients prospectively underwent MR enterography, including DWI and enteric and portal phase scans, and ileocolonoscopy with segmental CD endoscopic index of severity (CDEIS) scoring within a week...
February 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28216967/assessment-of-multi-modality-evaluations-of-obscure-gastrointestinal-bleeding
#13
Ryan Law, Jithinraj E Varayil, Louis M WongKeeSong, Jeff Fidler, Joel G Fletcher, John Barlow, Jeffrey Alexander, Elizabeth Rajan, Stephanie Hansel, Brenda Becker, Joseph J Larson, Felicity T Enders, David H Bruining, Nayantara Coelho-Prabhu
AIM: To determine the frequency of bleeding source detection in patients with obscure gastrointestinal bleeding (OGIB) who underwent double balloon enteroscopy (DBE) after pre-procedure imaging [multiphase computed tomography enterography (MPCTE), video capsule endoscopy (VCE), or both] and assess the impact of imaging on DBE diagnostic yield. METHODS: Retrospective cohort study using a prospectively maintained database of all adult patients presenting with OGIB who underwent DBE from September 1(st), 2002 to June 30(th), 2013 at a single tertiary center...
January 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28210767/crohn-s-disease-diagnosis-treatment-approach-and-management-paradigm-what-the-radiologist-needs-to-know
#14
Parakkal Deepak, Sang Hyoung Park, Eric C Ehman, Stephanie L Hansel, Jeff L Fidler, David H Bruining, Joel G Fletcher
Crohn's disease is one of the major subtypes of idiopathic inflammatory bowel disease and is characterized by chronic transmural intestinal inflammation of the gastrointestinal tract anywhere from mouth to the anus, with a predilection for the small bowel. Cross-sectional imaging with computed tomography and magnetic resonance enterography plays a key role in confirming diagnosis, identifying and managing complications, assessing disease severity, and identifying response to medical therapy. This review will focus on the role of radiologists in the diagnosis and assessment of Crohn's disease...
February 16, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28210706/single-balloon-enteroscopy-efficacy-and-degree-of-concordance-with-noninvasive-evaluation-of-small-bowel
#15
Margarida Marques, João Antunes, Rosa Coelho, Hélder Cardoso, Filipe Vilas Boas, Armando Ribeiro, Guilherme Macedo
Background and study aims Clinical impact of single-balloon enteroscopy (SBE) is fairly known, as well as its diagnostic yield comparing with other small bowel gastrointestinal investigations. This study represents a contribution to better understand it and is designed to evaluate SBE efficacy and degree of concordance with previous evaluation of small bowel. Patients and methods This is a single-center retrospective study of patients that underwent SBE with suspected small bowel disease based on non-invasive imaging...
February 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28193167/helicobacter-pylori-prevalence-and-clinical-significance-in-patients-with-quiescent-crohn-s-disease
#16
Adi Lahat, Uri Kopylov, Sandra Neuman, Nina Levhar, Doron Yablecovitch, Benjamin Avidan, Batia Weiss, Shomron Ben-Horin, Rami Eliakim
BACKGROUND: Helicobacter pylori (HP) infection is present in about 50% of the global population, and is associated with chronic gastritis, peptic disease and gastric malignancies. HP prevalence in Crohn's disease (CD) patients was shown to be low compared to the general population, and its influence on disease activity is yet to be determined. Our aims were to determine the prevalence of HP in a selected group of CD patients with quiescent disease, and to assess the influence of its eradication on disease activity and endoscopic and laboratory activity measures...
February 13, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28188060/mesenteric-findings-of-ct-enterography-are-well-correlated-with-the-endoscopic-severity-of-crohn-s-disease
#17
Takehiro Sakurai, Tatsuro Katsuno, Keiko Saito, Sayuri Yoshihama, Tomoo Nakagawa, Hirotaka Koseki, Takashi Taida, Hideaki Ishigami, Ken-Ichiro Okimoto, Daisuke Maruoka, Tomoaki Matsumura, Makoto Arai, Osamu Yokosuka
BACKGROUND: Maintenance of mucosal healing is a primary goal when treating Crohn's disease (CD). Endoscopy is the most precise method for the assessment of mucosal healing, but is considered overly invasive for patients with CD. In contrast, CT enterography (CTE) is less invasive, but little is known about the correlation between mucosal status and CTE parameters. METHODS: We recruited CD patients who underwent CTE and double balloon endoscopy (DBE) on the same day at our hospital between 2012 and 2014...
April 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28182308/mr-enterography-in-nonresponsive-adult-celiac-disease-correlation-with-endoscopic-pathologic-serologic-and-genetic-features
#18
Amir Reza Radmard, Amir Pejman Hashemi Taheri, Elham Salehian Nik, Soheil Kooraki, Shadi Kolahdoozan, Babak Mirminachi, Masoud Sotoudeh, Golnaz Ekhlasi, Reza Malekzadeh, Bijan Shahbazkhani
PURPOSE: To assess small bowel abnormalities on magnetic resonance enterography (MRE) in adult patients with nonresponsive celiac disease (CD) and investigate their associations with endoscopic, histopathologic, serologic, and genetic features. MATERIALS AND METHODS: This prospective study was carried out between September 2012 and August 2013. After approval by the Ethics Committee of our institution, informed consent was acquired from all participants. Forty consecutive patients with nonresponsive CD, aged 17-76 years, underwent MRE using a 1...
February 9, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28175122/p522-a-multicenter-study-to-validate-magnetic-resonance-enterography-against-histological-assessments-of-stenotic-disease-in-patients-with-crohn-s-disease
#19
A Coimbra, J Rimola, M Cuatrecasas, G De Hertogh, G Van Assche, R Vanslembrouck, H Glerup, A Hedemann Nielsen, R Hagemann-Madsen, Y Bouhnik, M Zappa, D Cazals-Hatem, G D'Haens, J Stoker, S Meijer, G Rogler, A Boss, A Weber, R Zhao, M Keir, A Scherl, A deCrespigny, T Lu, J Panes
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175046/p318-accuracy-of-magnetic-resonance-enterography-for-extraluminal-complications-of-crohn-s-disease
#20
G M Pecoraro, A Orlando, L TesÈ, G Solina, R Di Mitri, F Mocciaro, S Renna, M Cottone
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
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