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Sagar Pandey, Miao Fan, Zhe Xu, Chaogui Yan, Junfeng Zhu, Xiuhong Li
INTRODUCTION: Meckel diverticulum (MD) is the most common congenital abnormality of gastrointestinal tract. Tough believed to occur in 2% of population, most of them remain veiled because majority are clinically asymptomatic and remain obscure in radiological examination. CLINICAL FINDINGS AND DIAGNOSIS: A 26-year-old male with episodic black colored stool since last 10 years. Tough symptomatic, diagnosis of pathological lesion, and the bleeding site could not be established with any of the sophisticated diagnostic technique...
October 2016: Medicine (Baltimore)
Miyoung Choi, Sungwon Lim, Myung-Gyu Choi, Ki-Nam Shim, Seon Heui Lee
Background/Aims: As a result of the rapid development of medical diagnostic tools, physicians require concrete evidence to evaluate the effectiveness of the tools. We aimed to investigate the effectiveness and additional diagnostic benefits of capsule endoscopy (CE) in patients with small bowel Crohn's disease (CD). Methods: We performed a systematic search of databases, including MEDLINE, EMBASE, and the Cochrane Library, as well as eight domestic databases. Two reviewers independently screened all references...
October 13, 2016: Gut and Liver
Zehour AlSabban, Peter Church, Rahim Moineddin, Oscar M Navarro, Mary-Louise Greer, Thomas Walters, Govind B Chavhan
PURPOSE: To determine interobserver agreement (IOA) and accuracy of conventional MR enterography (MRE), qualitative diffusion, and apparent diffusion coefficient (ADC) values for detecting clinically active inflammation. METHODS: MREs in 57 consecutive children with suspected inflammatory bowel disease were retrospectively reviewed. RESULTS: Substantial IOA for conventional MRE (kappa=0.65) and qualitative diffusion (kappa=0.64), but fair to good IOA for ADC, (intra-class coefficient=0...
September 28, 2016: Clinical Imaging
Piotr Eder, Liliana Łykowska-Szuber, Katarzyna Katulska, Kamila Stawczyk-Eder, Iwona Krela-Kaźmierczak, Katarzyna Klimczak, Aleksandra Szymczak, Marek Stajgis, Krzysztof Linke
INTRODUCTION: Objective assessment of Crohn's disease (CD) activity in patients treated with anti-tumour necrosis factor (anti-TNF) antibodies is crucial for the prediction of its long-term results. Mucosal healing estimated endoscopically has a strong predictive value; however, only combined assessment together with transmural healing in magnetic resonance enterography (MRE) gives full information about the whole spectrum of inflammatory lesions in CD. AIM: To assess the usefulness of intestinal healing phenomenon in CD, defined as improvement both in endoscopy and MRE, after anti-TNF induction therapy, in predicting long-term results of 1-year treatment...
2016: Przegla̜d Gastroenterologiczny
Bosheng He, Jinhua Gu, Sheng Huang, Xuesong Gao, Jinhe Fan, Meihong Sheng, Lin Wang, Shenchu Gong
INTRODUCTION: This study was performed to evaluate the diagnostic performance of multi-slice CT angiography combined with enterography in determining the cause and location of obstruction as well as intestinal ischaemia in patients with small bowel obstruction (SBO). METHODS: This study retrospectively summarized the image data of 57 SBO patients who received both multi-slice CT angiography and enterography examination between December 2012 and May 2013. The CT diagnoses of SBO and intestinal ischaemia were correlated with the findings at surgery or digital subtraction angiography, which were set as standard references...
October 5, 2016: Journal of Medical Imaging and Radiation Oncology
So Hyun Park, Jimi Huh, Seong Ho Park, Seung Soo Lee, Ah Young Kim, Suk-Kyun Yang
OBJECTIVES: To prospectively investigate how Buscopan affects the diagnosis of bowel inflammation by diffusion-weighted imaging MR enterography (DWI-MRE) in Crohn's disease (CD). METHODS: Thirty CD patients without previous bowel surgery underwent DWI-MRE (b = 900 sec/mm(2)) before and after intravenous Buscopan. The 30 patients were randomly divided into two groups; using a crossover design, interpretations were made regarding the presence of restricted mural diffusion (i...
October 5, 2016: European Radiology
Sanne N van Munster, Mark F J Stolk, Karel C Kuypers, Rene Wiezer, Thomas L Bollen
No abstract text is available yet for this article.
August 2016: Quantitative Imaging in Medicine and Surgery
Daniel G Rosenbaum, Maire A Conrad, David M Biko, Eduardo D Ruchelli, Judith R Kelsen, Sudha A Anupindi
BACKGROUND: Imaging predictors for surgery in children with Crohn disease are lacking. OBJECTIVE: To identify imaging features of the terminal ileum on short-interval bowel ultrasound (US) and MR enterography (MRE) in children with Crohn disease requiring surgical bowel resection and those managed by medical therapy alone. MATERIALS AND METHODS: This retrospective study evaluated patients 18 years and younger with Crohn disease undergoing short-interval bowel US and MRE (within 2 months of one another), as well as subsequent ileocecectomy or endoscopy within 3 months of imaging...
September 29, 2016: Pediatric Radiology
Alexandre Nuzzo, Magaly Zappa, Dominique Cazals-Hatem, Yoram Bouhnik
BACKGROUND: Mesenteric panniculitis (MP) is mostly an associated sign of an intra-abdominal or systemic inflammatory primary disease. Nevertheless, etiological and differential diagnosis of idiopathic MP can be challenging when an associate primary cause is not in the foreground. METHODS: We report here the case of an isolated small bowel Crohn's disease, long time considered as idiopathic MP. RESULTS: This patient presented to our department with a 10-year history of acute abdominal symptoms evolving with flare-up and remission...
September 2016: Medicine (Baltimore)
Antoine Brouquet, Anne-Sophie Rangheard, Jonathan Ifergan, Thierry Lazure, Franck Carbonnel, Christophe Penna, Stéphane Benoist
AIM: The study aimed to evaluate the accuracy of imaging for the measurement of the length of the ileocolic segment affected by Crohn's disease. METHOD: Fifty-four consecutive patients who underwent resection between 2011 and 2014 for ileocolic Crohn's disease were prospectively studied. All had preoperative magnetic resonance (MR) or computed tomographic (CT) enterography. Two independent radiologists measured the length of the diseased intestinal segment. The measurements were compared with the length of disease assessed on pathology of the non-fixed surgical specimen...
September 8, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
Jordi Rimola, Almudena Alvarez-Cofiño, Tamara Pérez-Jeldres, Carmen Ayuso, Ignacio Alfaro, Sonia Rodríguez, Elena Ricart, Ingrid Ordás, Julián Panés
BACKGROUND: Magnetic resonance enterography (MRE) is an accurate examination for assessing activity in Crohn's disease (CD). Various MRE indices have been developed for that purpose, but have not been directly compared. The aim of the study was to compare the diagnostic accuracy of three MRE indices for detecting and grading disease activity in CD, using endoscopy as gold standard. METHODS: MRE and ileocolonoscopies performed within 1 month in 43 patients with CD were analyzed...
September 6, 2016: Journal of Gastroenterology
Uri Kopylov, Eyal Klang, Doron Yablecovitch, Adi Lahat, Benjamin Avidan, Sandra Neuman, Nina Levhar, Tomer Greener, Noa Rozendorn, Arkadi Beytelman, Henit Yanai, Iris Dotan, Yehuda Chowers, Batya Weiss, Shomron Ben-Horin, Marianne M Amitai, Rami Eliakim
BACKGROUND: Video capsule endoscopy (VCE) and magnetic resonance enterography (MRE) are the prime modalities for the evaluation of small bowel (SB) Crohn's disease (CD). Mucosal inflammation on VCE is quantified using the Lewis score (LS). Diffusion-weighted (DW) magnetic resonance imaging (MRI) allows for accurate assessment of SB inflammation without administration of intravenous contrast material. The Magnetic Resonance Index of Activity (MaRiA) and the Clermont index are quantitative activity indices validated for contrast-enhanced MRE and DW-MRE, respectively...
September 2016: Therapeutic Advances in Gastroenterology
Shadi Rajabi, Isabelle Dupuis, Amine Benmassaoud, Alexandre Prucha, Talat Bessissow, Caroline Reinhold, Lawrence A Stein, Benoit Gallix
No abstract text is available yet for this article.
August 28, 2016: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
Andrew H Schapiro, Tom K Lin, Jason S Frischer, Ayaka Silverman, Andrew T Trout
Extensive heterotopic gastric mucosa of the small intestine is a rare, but potentially life-threatening condition characterized by multifocal or long-segment heterotopic gastric mucosa within the bowel lumen that is often associated with other anomalies including malrotation and annular pancreas. Although the imaging findings are characteristic, this entity may be unrecognized due to its unusual imaging appearance and rarity. CT or MR enterography and (99m)Tc-sodium pertechnetate scintigraphy can provide complementary information that enables specific diagnosis and accurate assessment of disease extent...
August 29, 2016: Pediatric Radiology
D A Pendsé, J C Makanyanga, A A Plumb, G Bhatnagar, D Atkinson, Manuel Rodriguez-Justo, S Halligan, S A Taylor
PURPOSE: To evaluate whether the extent of enteric diffusion-weighted imaging (DWI) signal abnormality reflects inflammatory burden in Crohn's disease (CD), and to compare qualitative and quantitative grading. METHODS: 69 CD patients (35 male, age 16-78) undergoing MR enterography with DWI (MRE-D) and the same-day faecal calprotectin (cohort 1) were supplemented by 29 patients (19 male, age 16-70) undergoing MRE-D and terminal ileal biopsy (cohort 2). Global (cohort 1) and terminal ileal (cohort 2) DWI signal was graded (0 to 3) by 2 radiologists and segmental apparent diffusion coefficient (ADC) calculated...
August 27, 2016: Abdominal Radiology
Tsunetaka Arai, Ken Takeuchi, Miyuki Miyamura, Rumiko Ishikawa, Akihiro Yamada, Masao Katsumata, Yoshinori Igarashi, Yasuo Suzuki
BACKGROUND & AIMS: Previous studies have not found a correlation between fecal level of calprotectin and small bowel Crohn's disease (CD). However, these studies evaluated patients mainly by ileocolonoscopy, which views up to only the terminal ileum rather than entire small intestine. We investigated whether level of fecal calprotectin (FC) is a marker of active CD of the small bowel, identified by balloon-assisted enteroscopy and computed tomography enterography (CTE). METHODS: We performed a prospective study of 123 patients with CD (35 with ileitis, 72 with ileocolitis, and 16 with colitis) evaluated by balloon-assisted enteroscopy from May 2012 through July 2015 at Toho University Sakura Medical Centre in Japan...
August 23, 2016: Clinical Gastroenterology and Hepatology
Gabriele Masselli, Ilaria Mastroiacovo, Emidio De Marco, Giulia Francione, Emanuele Casciani, Elisabetta Polettini, Gianfranco Gualdi
Crohn's disease affects more than 500000 individuals in the United States, and about 25% of cases are diagnosed during the pediatric period. Imaging of the bowel has undergone dramatic changes in the past two decades. The endoscopy with biopsy is generally considered the diagnostic reference standard, this combination can evaluates only the mucosa, not inflammation or fibrosis in the mucosa. Actually, the only modalities that can visualize submucosal tissues throughout the small bowel are the computed tomography (CT) enterography (CTE) with the magnetic resonance enterography (MRE)...
July 28, 2016: World Journal of Radiology
Makoto Naganuma, Shigeo Okuda, Tadakazu Hisamatsu, Katsuyoshi Matsuoka, Kiyoto Mori, Naoki Hosoe, Yoshihiro Nakazato, Haruhiko Ogata, Takanori Kanai
BACKGROUND: MR enterography (MRE) is useful for evaluating transmural lesions and extra-intestinal complications of Crohn's disease (CD). The aim of this study was to prospectively evaluate whether MRE could detect severe strictures and inflammatory lesions in patients who lost the responsiveness to anti-TNF treatment and whether MRE could predict prognosis of CD patients with clinical remission. PATIENTS AND METHODS: MRE were conducted in 50 patients who were treated with infliximab or adalimumab...
August 23, 2016: Abdominal Radiology
Julajak Limsrivilai, Sitthipong Srisajjakul, Supot Pongprasobchai, Somchai Leelakusolvong, Tawesak Tanwandee
GOALS: To compare the efficacy of video capsule endoscopy (VCE) with computed tomography enterography (CTE) in potential small bowel (SB) bleeding, and to identify factors predictive of a high diagnostic yield for CTE. BACKGROUND: In potential SB bleeding, CTE potentially detects some lesions missed by VCE, but few data have determined its clinical utility. STUDY: Consecutive patients with potential SB bleeding were prospectively enrolled...
August 19, 2016: Journal of Clinical Gastroenterology
Parakkal Deepak, Joel G Fletcher, Jeff L Fidler, David H Bruining
Early recognition of Crohn's disease with initiation of disease-modifying therapy has emerged as a prominent inflammatory bowel disease management strategy. Clinical practice and trials have often focused on patient symptoms, and more recently, serologic tests, stool inflammatory markers, and/or endoscopic inflammatory features for study entry criteria, treatment targets, disease activity monitoring, and to assess therapeutic response. Unfortunately, patient symptoms do not correlate well with biological disease activity, and endoscopy potentially misses or underestimates disease extent and severity in small bowel Crohn's disease...
September 2016: Inflammatory Bowel Diseases
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