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https://www.readbyqxmd.com/read/28210767/crohn-s-disease-diagnosis-treatment-approach-and-management-paradigm-what-the-radiologist-needs-to-know
#1
Parakkal Deepak, Sang Hyoung Park, Eric C Ehman, Stephanie L Hansel, Jeff L Fidler, David H Bruining, Joel G Fletcher
Crohn's disease is one of the major subtypes of idiopathic inflammatory bowel disease and is characterized by chronic transmural intestinal inflammation of the gastrointestinal tract anywhere from mouth to the anus, with a predilection for the small bowel. Cross-sectional imaging with computed tomography and magnetic resonance enterography plays a key role in confirming diagnosis, identifying and managing complications, assessing disease severity, and identifying response to medical therapy. This review will focus on the role of radiologists in the diagnosis and assessment of Crohn's disease...
February 16, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28210706/single-balloon-enteroscopy-efficacy-and-degree-of-concordance-with-noninvasive-evaluation-of-small-bowel
#2
Margarida Marques, João Antunes, Rosa Coelho, Hélder Cardoso, Filipe Vilas Boas, Armando Ribeiro, Guilherme Macedo
Background and study aims Clinical impact of single-balloon enteroscopy (SBE) is fairly known, as well as its diagnostic yield comparing with other small bowel gastrointestinal investigations. This study represents a contribution to better understand it and is designed to evaluate SBE efficacy and degree of concordance with previous evaluation of small bowel. Patients and methods This is a single-center retrospective study of patients that underwent SBE with suspected small bowel disease based on non-invasive imaging...
February 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28193167/helicobacter-pylori-prevalence-and-clinical-significance-in-patients-with-quiescent-crohn-s-disease
#3
Adi Lahat, Uri Kopylov, Sandra Neuman, Nina Levhar, Doron Yablecovitch, Benjamin Avidan, Batia Weiss, Shomron Ben-Horin, Rami Eliakim
BACKGROUND: Helicobacter pylori (HP) infection is present in about 50% of the global population, and is associated with chronic gastritis, peptic disease and gastric malignancies. HP prevalence in Crohn's disease (CD) patients was shown to be low compared to the general population, and its influence on disease activity is yet to be determined. Our aims were to determine the prevalence of HP in a selected group of CD patients with quiescent disease, and to assess the influence of its eradication on disease activity and endoscopic and laboratory activity measures...
February 13, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28188060/mesenteric-findings-of-ct-enterography-are-well-correlated-with-the-endoscopic-severity-of-crohn-s-disease
#4
Takehiro Sakurai, Tatsuro Katsuno, Keiko Saito, Sayuri Yoshihama, Tomoo Nakagawa, Hirotaka Koseki, Takashi Taida, Hideaki Ishigami, Ken-Ichiro Okimoto, Daisuke Maruoka, Tomoaki Matsumura, Makoto Arai, Osamu Yokosuka
BACKGROUND: Maintenance of mucosal healing is a primary goal when treating Crohn's disease (CD). Endoscopy is the most precise method for the assessment of mucosal healing, but is considered overly invasive for patients with CD. In contrast, CT enterography (CTE) is less invasive, but little is known about the correlation between mucosal status and CTE parameters. METHODS: We recruited CD patients who underwent CTE and double balloon endoscopy (DBE) on the same day at our hospital between 2012 and 2014...
November 27, 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/28182308/mr-enterography-in-nonresponsive-adult-celiac-disease-correlation-with-endoscopic-pathologic-serologic-and-genetic-features
#5
Amir Reza Radmard, Amir Pejman Hashemi Taheri, Elham Salehian Nik, Soheil Kooraki, Shadi Kolahdoozan, Babak Mirminachi, Masoud Sotoudeh, Golnaz Ekhlasi, Reza Malekzadeh, Bijan Shahbazkhani
PURPOSE: To assess small bowel abnormalities on magnetic resonance enterography (MRE) in adult patients with nonresponsive celiac disease (CD) and investigate their associations with endoscopic, histopathologic, serologic, and genetic features. MATERIALS AND METHODS: This prospective study was carried out between September 2012 and August 2013. After approval by the Ethics Committee of our institution, informed consent was acquired from all participants. Forty consecutive patients with nonresponsive CD, aged 17-76 years, underwent MRE using a 1...
February 9, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28175122/p522-a-multicenter-study-to-validate-magnetic-resonance-enterography-against-histological-assessments-of-stenotic-disease-in-patients-with-crohn-s-disease
#6
A Coimbra, J Rimola, M Cuatrecasas, G De Hertogh, G Van Assche, R Vanslembrouck, H Glerup, A Hedemann Nielsen, R Hagemann-Madsen, Y Bouhnik, M Zappa, D Cazals-Hatem, G D'Haens, J Stoker, S Meijer, G Rogler, A Boss, A Weber, R Zhao, M Keir, A Scherl, A deCrespigny, T Lu, J Panes
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175046/p318-accuracy-of-magnetic-resonance-enterography-for-extraluminal-complications-of-crohn-s-disease
#7
G M Pecoraro, A Orlando, L TesÈ, G Solina, R Di Mitri, F Mocciaro, S Renna, M Cottone
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28175024/p185-validity-of-contrast-enhanced-ultrasonography-and-dynamic-contrast-enhanced-mr-enterography-in-the-assessment-of-crohn-s-disease
#8
R Wilkens, R Hagemann-Madsen, D A Peters, A H Nielsen, C B Nørager, H Glerup, K Krogh
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172526/p160-diagnostic-yield-of-capsule-endoscopy-versus-magnetic-resonance-enterography-and-small-bowel-contrast-ultrasound-for-evaluation-of-small-bowel-crohn-s-disease-a-systematic-review-and-meta-analysis
#9
U Kopylov, D Young, T Engel, S Vijayan, O Har-Noy, L Katz, T Avni, R Eliakim, S Ben-Horin, A Koulaouzidis
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28153484/magnetic-resonance-enterography-in-pediatric-celiac-disease
#10
Gonca Koc, Selim Doganay, Eylem Sevinc, Kemal Deniz, Govind Chavhan, Sureyya B Gorkem, Neslihan Karacabey, Mehmet S Dogan, Abdulhakim Coskun, Duran Aslan
OBJECTIVE: To assess if magnetic resonance enterography is capable of showing evidence/extent of disease in pediatric patients with biopsy-proven celiac disease by comparing with a control group, and to correlate the magnetic resonance enterography findings with anti-endomysial antibody level, which is an indicator of gluten-free dietary compliance. METHODS: Thirty-one pediatric patients (mean age 11.7±3.1 years) with biopsy-proven celiac disease and 40 pediatric patients as a control group were recruited in the study...
January 31, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28139500/variation-in-inflammatory-bowel-disease-care-among-saudi-pediatric-gastroenterologists
#11
Ahmed A Al-Sarkhy
BACKGROUND/AIM: Although international guidelines in inflammatory bowel disease (IBD) management are currently available, variations in IBD care still exist. The aim of this study was to determine the extent of the variation in IBD care among Saudi pediatric gastroenterologists. MATERIALS AND METHODS: A cross-sectional survey was conducted among all pediatric gastroenterologists who were members of the Saudi Society of Pediatric Gastroenterology, Hepatology, and Nutrition (SASPGHAN) from August 2015 to December 2015...
January 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28119352/efficacy-of-adalimumab-in-patients-with-crohn-s-disease-and-symptomatic-small-bowel-stricture-a-multicentre-prospective-observational-cohort-creole-study
#12
Yoram Bouhnik, Franck Carbonnel, David Laharie, Carmen Stefanescu, Xavier Hébuterne, Vered Abitbol, Maria Nachury, Hedia Brixi, Arnaud Bourreille, Laurence Picon, Anne Bourrier, Matthieu Allez, Laurent Peyrin-Biroulet, Jacques Moreau, Guillaume Savoye, Mathurin Fumery, Stephane Nancey, Xavier Roblin, Romain Altwegg, Guillaume Bouguen, Gilles Bommelaer, Silvio Danese, Edouard Louis, Magaly Zappa, Jean-Yves Mary
OBJECTIVE: The efficacy of anti-tumour necrosis factors (anti-TNFs) in patients with Crohn's disease (CD) and symptomatic small bowel stricture (SSBS) is controversial. The aim of this study was to estimate the efficacy of adalimumab in these patients and to identify the factors predicting success. DESIGN: We performed a multicentre, prospective, observational cohort study in patients with CD and SSBS. The included patients underwent magnetic resonance enterography at baseline and subsequently received adalimumab...
January 24, 2017: Gut
https://www.readbyqxmd.com/read/28116809/accuracy-of-magnetic-resonance-enterography-in-the-preoperative-assessment-of-patients-with-small-bowel-crohn-s-disease
#13
Salvador Pous-Serrano, Matteo Frasson, Rosana Palasí Giménez, Gonzalo Sanchez-Jordá, Jose Pamies-Guilabert, Margarita Llavador Ros, Pilar Nos Mateu, Eduardo Garcia-Granero
AIM: to assess the accuracy of magnetic resonance-enterography in predicting the extension, location and characteristics of the small bowel segments affected by Crohn's disease. METHOD: This is a prospective study including a consecutive series of 38 patients with small bowel Crohn's disease who underwent surgery at a specialized colorectal unit of a tertiary hospital. Preoperative magnetic resonance enterography was performed in all patients, following a homogeneous protocol, within the three months prior to surgery...
January 24, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28096726/diffusion-weighted-mr-enterography-to-monitor-bowel-inflammation-after-medical-therapy-in-crohn-s-disease-a-prospective-longitudinal-study
#14
Jimi Huh, Kyung Jo Kim, Seong Ho Park, So Hyun Park, Suk-Kyun Yang, Byong Duk Ye, Sang Hyoung Park, Kyunghwa Han, Ah Young Kim
OBJECTIVE: To prospectively evaluate the performance of diffusion-weighted imaging (DWI) to monitor bowel inflammation after medical therapy for Crohn's disease (CD). MATERIALS AND METHODS: Before and following 1-2 years of medical therapy, between October 2012 and May 2015, 18 randomly selected adult CD patients (male:female, 13:5; mean age ± SD, 25.8 ± 7.9 years at the time of enrollment) prospectively underwent MR enterography (MRE) including DWI (b = 900 s/mm(2)) and ileocolonoscopy...
January 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28094231/improving-efficiency-using-time-driven-activity-based-costing%C3%A2-methodology
#15
Laura C Tibor, Stacy R Schultz, Ronald Menaker, Bradley D Weber, Jay Ness, Paula Smith, Phillip M Young
PURPOSE: The aim of this study was to increase efficiency in MR enterography using a time-driven activity-based costing methodology. METHODS: In February 2015, a multidisciplinary team was formed to identify the personnel, equipment, space, and supply costs of providing outpatient MR enterography. The team mapped the current state, completed observations, performed timings, and calculated costs associated with each element of the process. The team used Pareto charts to understand the highest cost and most time-consuming activities, brainstormed opportunities, and assessed impact...
January 11, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28079618/diffusion-weighted-mri-enables-to-accurately-grade-inflammatory-activity-in-patients-of-ileocolonic-crohn-s-disease-results-from-an-observational-study
#16
Xue-Hua Li, Can-Hui Sun, Ren Mao, Si-Yun Huang, Zhong-Wei Zhang, Xu-Feng Yang, Li Huang, Jin-Jiang Lin, Jian Zhang, Shomron Ben-Horin, Shi-Ting Feng, Min-Hu Chen, Zi-Ping Li
BACKGROUND: Diffusion-weighted imaging (DWI) is a novel technique to evaluate bowel inflammation in Crohn's disease (CD). It remains unclear whether DWI could differentiate grades of inflammation activity and add to the accuracy of conventional magnetic resonance enterography (MRE) in defining disease activity. We aimed to assess the accuracy of DWI for evaluating ileocolonic CD inflammation compared with conventional MRE, using ileocolonoscopy as reference standard. METHODS: This was an observational study of CD patients who underwent both ileocolonoscopy and MRE with DWI...
February 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28069475/retention-associated-with-video-capsule-endoscopy-systematic-review-and-meta-analysis
#17
REVIEW
Mona Rezapour, Chidi Amadi, Lauren Gerson
BACKGROUND: Video capsule endoscopy (VCE) has become a major diagnostic tool for small-bowel evaluation. However, retention of the video capsule endoscope remains a major concern. METHODS: We performed a systematic review of VCE retention rates using Pubmed and SCOPUS (1995-2015). We included studies that enrolled at least 10 subjects, included VCE retention rates, and separated retention rates by indication. We used Comprehensive Meta-Analysis (Version 3.0) to calculate pooled prevalence rates with 95% confidence intervals and assessed heterogeneity using Cochran's Q statistic...
January 6, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28062089/structured-reporting-of-magnetic-resonance-enterography-for-pediatric-crohn-s-disease-effect-on-key-feature-reporting-and-subjective-assessment-of-disease-by-referring-physicians
#18
Benjamin Wildman-Tobriner, Brian C Allen, Joseph T Davis, Chad M Miller, Gary R Schooler, Nancy M McGreal, Reinaldo Quevedo, Julie K Thacker, Tracy A Jaffe
PURPOSE: To objectively compare the content of structured reports (SR) vs nonstructured reports (NSR) for magnetic resonance enterography (MRE) of pediatric patients with Crohn's disease, and to evaluate referring clinicians' subjective assessment of reports. METHODS: This institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study included 25 pediatric subjects (15 male, 10 female; mean age = 14 years [range: 9-18 years]) with Crohn's disease imaged with MRE...
December 5, 2016: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28058450/collagenous-sprue-cross-sectional-imaging-a-comparative-blinded-study
#19
Badr Al-Bawardy, Shannon P Sheedy, Michelle B Herberts, Joseph A Murray, Alberto Rubio-Tapia, Elizabeth Rajan, David H Bruining, Stephanie L Hansel, John M Barlow, Joel G Fletcher, Jeff L Fidler
PURPOSE: Collagenous sprue (CS) is a rare enteropathy characterized by villous atrophy and a thickened subepithelial collagen band. The aim of this study is to describe the cross-sectional imaging findings of CS. METHODS: A case-control, retrospective study with cases of all CS patients from January 2000 to 2015 was performed. Inclusion criteria were (1) Histopathologic diagnosis and (2) Imaging with computed tomography abdomen/pelvis (CT A/P), CT enterography (CTE), or magnetic resonance enterography within 6 months of small bowel (SB) biopsy...
January 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28058449/impact-of-ct-enterography-on-the-diagnosis-of-small-bowel-gastrointestinal-stromal-tumors
#20
Rogerio N Vasconcelos, Steven G Dolan, John M Barlow, Michael L Wells, Shannon P Sheedy, Jeff L Fidler, Stephanie Hansel, Scott Harmsen, Joel G Fletcher
OBJECTIVE: Our purpose is to determine the impact of CT enterography on small bowel gastrointestinal stromal tumor (GIST) detection and biologic aggressiveness, and to identify any imaging findings that correlate with biologic aggressiveness. METHODS: Records of patients with histologically confirmed small bowel GISTs who underwent CT imaging were reviewed. Biologic aggressiveness was based on initial histologic grading (very low, low, intermediate, high grade; or malignant), with upgrade to malignant category if local or distant metastases developed during clinical follow-up...
January 5, 2017: Abdominal Radiology
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