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Acoustic neurinoma

Daniel Rueß, Lea Pöhlmann, Stefan Grau, Christina Hamisch, Alexandra Hellerbach, Harald Treuer, Martin Kocher, Maximilian I Ruge
BACKGROUND: The management of solely intracanalicular acoustic neurinoma (iAN) includes observation, microsurgical resection and radiation therapy. Treatment goals are long-term tumor control, hearing preservation and concurrently low side-effects. Stereotactic radiosurgery (SRS) has evolved as an alternative first-line treatment for small AN. Here we report about the long-term follow-up of a unique cohort of patients with iAN after LINAC or Cyberknife® based SRS. METHODS: In this single center retrospective analysis, we included all patients with iAN who underwent single session LINAC or Cyberknife® based SRS between 1993 and 2015, and who had a minimum follow-up period of six weeks...
April 21, 2017: Radiation Oncology
Khandkar Ali Kawsar, Md Raziul Haque, Forhad Hossain Chowdhury
Neurofibromatosis-2 (NF2) is an autosomal-dominant disease, which is characterized by vestibular schwannomas (VSs) (acoustic neurinoma) as well as tumours of the peripheral and central nervous system, demonstrating a variety of expression. A 12-year-old girl presented to us with headache and ataxia for four months. We examined and found a lump in the right side of her abdomen. On magnetic resonance imaging (MRI) of brain, a bilateral VS at the cerebellopontine (CP) angle was detected, and on computerized tomography (CT) scan and ultrasonography of her abdomen a large retroperitoneal schwannoma was revealed in the right side of her abdomen...
January 2017: Asian Journal of Neurosurgery
WenMing Hong, HongWei Cheng, XiaoJie Wang, ChunGuo Feng
OBJECTIVE: To explore and analyze the influencing factors of facial nerve function retainment after microsurgery resection of acoustic neurinoma. METHODS: Retrospective analysis of our hospital 105 acoustic neuroma cases from October, 2006 to January 2012, in the group all patients were treated with suboccipital sigmoid sinus approach to acoustic neuroma microsurgery resection. We adopted researching individual patient data, outpatient review and telephone followed up and the House-Brackmann grading system to evaluate and analyze the facial nerve function...
March 2017: Journal of Korean Neurosurgical Society
Genshu Tate, Koji Kishimoto, Toshiyuki Mitsuya
Meningiomas may be classified as neurofibromin 2 (NF2)-associated and non-NF2 meningiomas depending on the presence or absence of molecular alterations in the NF2 gene. One of the characteristic histological features of meningiomas is the whorl formation of neoplastic arachnoid cells. NF2 is a human homolog of the Drosophila gene, Merlin (Mer). In humans, NF2 is the gene responsible for the disease neurofibromatosis type II, which results in the development of brain tumors, including acoustic neurinoma and meningioma...
November 2016: Oncology Letters
V N Shimansky, V K Poshataev, D A Odamanov, K V Shevchenko
INTRODUCTION: Liquorrhea is a condition characterized by cerebrospinal fluid (CSF) leakage from the cranial cavity due to injury to the integrity of the dura mater (DM) and bone structures of the skull base. Surgery for posterior cranial fossa (PCF) lesions distinguishes wound CSF leakage when CSF leaks from a surgical wound as well as basal CSF leakage (nasal liquorrhea and, less often, otoliquorrhea). The main cause of basal CSF leakage is injury (including surgical injury) resulting in a defect in the DM and bone structures (cells of the mastoid process in the case of a suboccipital retrosigmoid approach)...
2016: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
Atul Goel
No abstract text is available yet for this article.
July 2016: Journal of Craniovertebral Junction and Spine
Haishi Zhang, Jian Xu, Danqi Chen, Xiang Huang, Ping Zhong
Here we reported the first case of left cerebellopontine angle acoustic neurinoma with calcification in our department. The patient was 65 year-old, suffering from progressive loss of hearing in the left ear for about 30 years and headache with unsteady gait for approximately 6 months. Head CT & MRI scan identified an intracranial lesion located on left cerebellopontine angle. Left suboccipital retrosigmoid approach was applied to perform the operation after patient consent. The tumor was completely resected without complication and the patient recovered well...
2015: International Journal of Clinical and Experimental Medicine
Andrea P Sponghini, Francesca Platini, David Rondonotti, Riccardo Soffietti
PURPOSE: Neurofibromatosis type 2 (NF2) is a dominantly inherited genetic condition that clinically manifests through the appearance of multiple meningiomas, ependymomas and bilateral vestibular schwannomas (acoustic neuromas) which lead to progressive hearing loss. Neovascularization is necessary for tumor growth and is driven by tumor-produced angiogenic factors such as vascular endothelial growth factor (VEGF). Bevacizumab is a humanized monoclonal antibody that neutralizes the activity of VEGF...
November 14, 2015: Tumori
Cleopatra Charalampaki
INTRODUCTION: Confocal laser endoscopy (CLE) is a novel technique permitting in vivo histologic imaging with miniaturized endoscopic probes at excellent resolution. The goal was: 1) to analyze the technical aspects of CLE technique, 2) to investigate the integration of CLE in the neurosurgical daily workflow in the operation room, 3) to create an easy integration of the CLE technique into the neurosurgical daily routine using endoscopic setting and providing immediate and intraoperative histopathologic diagnosis of the entire entity on real time, and 4) to evaluate CLE for in vivo diagnosis in different types and models of intracranial and intraspinal neoplasia...
August 2014: Neurosurgery
Sara Massironi, Alessandra Zilli, Roberta Elisa Rossi, Federica Cavalcoli, Dario Conte, Maddalena Peracchi
BACKGROUND: Gastroenteropancreatic neuroendocrine tumors have occasionally been described in association with neurofibromatosis type 1, whereas an association with neurofibromatosis type 2 has never been reported. CASE PRESENTATION: This report refers to an Italian 69 year old woman with neurofibromatosis type 2 and a pancreatic gastrinoma. In the past she had encephalic meningiomas, a tongue schwannoma and bilateral acoustic neurinomas. She presented with weight loss and a long-term history of diarrhea, responsive to proton pump inhibitors...
June 24, 2014: BMC Gastroenterology
Hisato Nakazawa, Masataka Komori, Yuta Shibamoto, Takahiko Tsugawa, Yoshimasa Mori, Tatsuya Kobayashi
BACKGROUND: The treatment planning for Gamma Knife (GK) stereotactic radiosurgery (SRS) that performs dose calculations based on tissue maximum ratio (TMR) algorithm has disadvantages in predicting dose in tissue heterogeneity. The latest version of the planning software is equipped with a convolution dose algorithm as an optional extra and the new algorithm is able to compensate for head inhomogeneity. However, the effect of this improved calculation method requires detailed validation in clinical cases...
August 2014: Acta Neurochirurgica
Gloria Guerra-Jiménez, Pilar Camargo Camacho, Ángel Ramos-Macías, Carmelo Morales Angulo
INTRODUCTION AND OBJECTIVES: Neurofibromatosis type 2 (NF2) is an infrequent autosomal dominant disease characterised by the appearance of viii nerve schwannomas, meningiomas and ocular abnormalities. Incidence of 1:25,000 and prevalence above 1:80,000 are estimated in general. The objectives of our study were to determine current prevalence of NF2 in the Community of Cantabria and the province of Las Palmas, and its head and neck manifestations. MATERIAL AND METHODS: This was a population-based, retrospective study in 3 tertiary hospitals...
May 2014: Acta Otorrinolaringológica Española
Karima Idrissi Serhrouchni, Laila Chbani, Nawal Hammas, Dounia Kamal, Hinde El Fatemi, Taoufik Harmouch, Noure-Eddine El Alami, Afaf Amarti
UNLABELLED: Twenty-five to 45 percent of all schwannomas occur in the head and neck. Most of them arise along the vestibular portion of the eighth cranial nerve (acoustic neurinoma). They rarely originate from the peripheral facial nerve or other nerves within the parotid gland. Less than 4% of schwannomas involve the nasal cavity and paranasal sinuses. They arise from the branches of the trigeminal nerve and autonomic nervous system.We report two cases of schwannomas arisng from intraparotid facial nerve and nasal cavity...
2014: Diagnostic Pathology
V Valentino, M Benassi, L Strigari
The central question of stereotaxic radiosurgery in acoustic neurinomas is how to pinpoint its main objective: is it a better alternative to neurosurgery or an option when surgery is unfeasible? This study is a continuation of the article published in 1995 in Acta Neurochirurgica, but benefits from greater experience, more complete analysis and longer supervision of results. The conclusions that can be drawn to date from our own findings and from others in the literature are the following: radiosurgery can be used not only to prevent neurinoma growth and at the same time to preserve the patient's neurological conditions without the risk of complications, but it can also be counted on to provide a cure...
November 30, 2006: Neuroradiology Journal
Bernardo Hontanilla, Diego Marre, Alvaro Cabello
Our aim was to describe our experience with the masseteric nerve in the reanimation of short term facial paralysis. We present our outcomes using a quantitative measurement system and discuss its advantages and disadvantages. Between 2000 and 2012, 23 patients had their facial paralysis reanimated by masseteric-facial coaptation. All patients are presented with complete unilateral paralysis. Their background, the aetiology of the paralysis, and the surgical details were recorded. A retrospective study of movement analysis was made using an automatic optical system (Facial Clima)...
February 2014: British Journal of Oral & Maxillofacial Surgery
Renata Conforti, Pierluigi Faella, Assunta Sica, Nicola Landi, Angela Faggian, Mario Amato, Antonio Raucci, Assunta Scuotto
The purpose of this paper is to study acoustic neuroma diagnostic process, describe tumor's molecular basis and its magnetic resonance imaging characterization, which is considered to be the gold standard diagnostic tool to study this disease.
July 2013: Recenti Progressi in Medicina
Qi-lin Gong, Ai-dong Zhou, Chang Lin
OBJECTIVE: Retrospectively analyzed the clinical data of sudden sensorineural hearing loss with acoustic neuroma. METHODS: The clinical data of 467 cases with sudden sensorineural hearing loss were collected between Jan, 2008 and Aug, 2012. Discussed the clinical data which were diagnosed as acoustic neuroma. RESULTS: In 467 cases of sudden sensorineural hearing loss, nine cases were diagnosed as acoustic neuromas (9 ears, 1.93%), two males and seven females, with a age range of 28 to 57 years...
April 2013: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Aida Antuña Ramos, Marco Antonio Alvarez Vega, Hernan Sandoval Valencia, Juan Campos García, Vicente Calatayud Perez
Schwannomas are tumors derived from the Schwann cells, which form the myelin sheath of the peripheral nerves. Fewer than 1% of these tumors occur within the brain parenchyma without arising from the cranial nerves. Only 55 cases have been published after the first recorded case. We report a 17-year-old girl with a 3-month history of unspecific dizziness, unsteadiness, and headache. Magnetic resonance imaging showed a heterogeneous cystic lesion involving midbrain, pons, and left cerebellar peduncle. The patient underwent a retromastoid craniotomy with complete resection of the tumor...
June 2013: Pediatric Neurology
Nikolaos Machairiotis, Paul Zarogoulidis, Aikaterini Stylianaki, Eleni Karatrasoglou, Georgia Sotiropoulou, Alvin Floreskou, Eleana Chatzi, Athanasia Karamani, Georgia Liapi, Eleni Papakonstantinou, Nikolaos Katsikogiannis, Nikolaos Courcoutsakis, Christodoulos Machairiotis
Neurilemomas are benign usually encapsulated nerve sheath tumors derived from the Schwann cells. These tumors commonly arise from the cranial nerves as acoustic neurinomas but they are extremely rare in the pelvis and the retroperitoneal area (less than 0.5% of reported cases), unless they are combined with von Recklinghausen disease (type 1 neurofibromatosis). We report the case of a 58-year-old female with pelvic schwannoma, 6.5 × 5.5 cm in size, in the right parametrium. This is the first case reported in the literature...
2013: International Journal of General Medicine
Yuefei Deng, Meiguang Zheng, Jinquan Wu
OBJECTIVE: To investigate the effectiveness and adverse effect of the absorbable fixation system on cranial bone flap reposition and fixation after craniotomy. METHODS: Between July 2010 and December 2011, 67 cases underwent cranial bone flap reposition and fixation with absorbable fixation system after craniotomy and resection of intracranial lesions. There were 38 males and 29 females with a median age of 32 years (range, 5 months to 73 years). The disease duration ranged from 3 months to 6 years (median, 25 months)...
October 2012: Chinese Journal of Reparative and Reconstructive Surgery
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