keyword
MENU ▼
Read by QxMD icon Read
search

Vulvar cancer

keyword
https://www.readbyqxmd.com/read/29145324/a-rare-case-of-merkel-cell-carcinoma-presenting-as-a-giant-intra-thoracic-mass-a-case-report-and-review-of-the-literature
#1
Feng-Wei Kong, Miao Zhang, Heng Wang, Cun-Tao Lu, Wen-Bin Wu, Yuan-Yuan Liu
RATIONALE: Merkel cell carcinoma (MCC) is an aggressive neuroendocrine-derived cutaneous cancer. Ectopic or single metastatic MCC located in thorax is extremely rare; meanwhile, its definite management has not been elucidated yet. PATIENT CONCERNS: A 64-year-old female patient with a giant mass located in her left thorax was presented for stuffy pain of left chest for 6 months and fever for half a month. She underwent radical resection of vulvar MCC 10 years ago...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145314/incidence-of-lower-limb-lymphedema-after-vulvar-cancer-a-systematic-review-and-meta-analysis
#2
Jiuzuo Huang, Nanze Yu, Xiaojun Wang, Xiao Long
BACKGROUND: Lower limb lymphedema (LLL) is an important concern for patients with vulvar cancer. Studies of the incidence of vulvar cancer-related lymphedema and its risk factors have substantially increased in the new millennium. OBJECTIVES: This article is a meta-analysis that aimed to systematically evaluate the incidence of LLL and its risk factors related to vulvar cancer. DATA SOURCES: Data were collected from eligible studies from PubMed, ScienceDirect, and Web of Science...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135982/sting-expression-and-response-to-treatment-with-sting-ligands-in-premalignant-and-malignant-disease
#3
Jason R Baird, Zipeng Feng, Hong D Xiao, David Friedman, Ben Cottam, Bernard A Fox, Gwen Kramer, Rom S Leidner, R Bryan Bell, Kristina H Young, Marka R Crittenden, Michael J Gough
Human papilloma virus positive (HPV+) tumors represent a large proportion of anal, vulvar, vaginal, cervical and head and neck squamous carcinomas (HNSCC) and late stage invasive disease is thought to originate from a premalignant state. Cyclic dinucleotides that activate STimulator of INterferon Genes (STING) have been shown to cause rapid regression of a range of advanced tumors. We aimed to investigate STING ligands as a novel treatment for papilloma. We tested therapies in a spontaneous mouse model of papilloma of the face and anogenital region that histologically resembles human HPV-associated papilloma...
2017: PloS One
https://www.readbyqxmd.com/read/29126556/vulvar-intraepithelial-neoplasia-risk-factors-for-recurrence
#4
W Satmary, C H Holschneider, L L Brunette, S Natarajan
OBJECTIVE: We studied a large population of women with high-grade vulvar intraepithelial neoplasia (VIN) in order to identify patient and treatment-related risk factors for recurrence and progression to cancer. METHODS: For this retrospective cohort study of women with a histologic diagnosis of VIN within Southern California Permanente Medical Group between 1995 and 2007 medical records were reviewed; clinical, demographic and pathologic data were collected. Statistical analyses included Chi-squared and Student's t-tests, univariate and multivariate logistic regression, and cumulative incidence analysis...
November 7, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29121621/a-review-of-squamous-cell-vulvar-cancers-in-waikato-region-new-zealand
#5
Prashanth Hari Dass, Marion Jj Kuper-Hommel
BACKGROUND: Squamous cell vulvar cancers (SCVC) are rare. Although management guidelines have recently been published, New Zealand studies presenting "real world" outcomes are limited. METHODS: Retrospective single-centre review of SCVC diagnosed between 1 January 2000 and 31 August 2015. Clinical characteristics and outcomes were reviewed. RESULTS: Among 47 cases reviewed, 38 were ethnically European and 9 Māori. Cases identified as Stage 1 (16), Stage 2 (5), Stage 3 (17), Stage 4 (9)...
November 10, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29113672/vulvo-vaginal-reconstruction-after-radical-excision-for-treatment-of-vulvar-cancer-evaluation-of-feasibility-and-morbidity-of-different-surgical-techniques
#6
REVIEW
Violante Di Donato, Carlotta Bracchi, Emanuele Cigna, Lavinia Domenici, Angela Musella, Andrea Giannini, Francesca Lecce, Claudia Marchetti, Pierluigi Benedetti Panici
BACKGROUND: Vulvar cancer is a rare disease accounting for approximately 5% of female genital tract tumors worldwide. Currently surgery represents the mainstay alone or sometimes, in combination with chemo-radiotherapy, for locally advanced tumors and recurrent disease. However, significant physical and sexual impairment mostly due to anatomical distortion of external genitalia are a consequence of radical surgical treatment. Postoperative reconstruction after demolitive surgeries improves aesthetic and functional results, guarantees an adequate coverage of large tumors and assures safe surgical margin...
December 2017: Surgical Oncology
https://www.readbyqxmd.com/read/29113037/vitamin-d-and-vdr-in-gynecological-cancers-a-systematic-review
#7
REVIEW
Eileen Deuster, Udo Jeschke, Yao Ye, Sven Mahner, Bastian Czogalla
In recent years, a vast amount of studies have centered on the role of vitamin D in the pathogenesis of certain types of cancers such as breast, colorectal and lung cancer. Increasing evidence suggests that vitamin D and its receptor play a crucial role in the development of gynecological cancers. In this review, we systematically analyzed the effect of vitamin D and the vitamin D receptor on endometrial, ovarian, cervical, vulvar and vaginal cancer. Our literature research shows that vitamin D levels and vitamin-D-related pathways affect the risk of gynecological cancers...
November 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29109863/pattern-of-gynaecological-malignancies-in-south-western-region-of-pakistan-an-overview-of-12-years
#8
Hina Manzoor, Hamida Naheed, Khushnaseeb Ahmad, Shehla Iftikhar, Muhammad Asif, Jamila Shuja, Neelam Sultan, Irfan Ali, Syed Inayatullah, Yasir Hayat Khan
Gynaecological malignancies contribute significantly to cancer burden and have a higher rate of mortality and morbidity. The aim of this retrospective study was to determine the pattern of gynaecological malignancies identified between January, 2000 and December, 2011, at the Centre for Nuclear Medicine and Radiotherapy (CENAR). At CENAR 5,072 female patients were registered with different malignancies, of which 632 cases were gynaecological malignancies. Ovarian cancer (47%) was the most common gynaecological malignancy, followed by cervical cancer (29%), uterine cancer (14%), vulvar and vaginal cancer (6%), and gestational trophoblastic neoplasm (4%)...
November 2017: Biomedical Reports
https://www.readbyqxmd.com/read/29105738/five-year-relative-survival-for-human-papillomavirus-associated-cancer-sites
#9
Hilda Razzaghi, Mona Saraiya, Trevor D Thompson, S Jane Henley, Laura Viens, Reda Wilson
BACKGROUND: Human papillomavirus (HPV) vaccines can potentially prevent greater than 90% of cervical and anal cancers as well as a substantial proportion of vulvar, vaginal, penile, and oropharyngeal cancers caused by certain HPV types. Because more than 38,000 HPV-associated cancers are diagnosed annually in the United States, current studies are needed to understand how relative survival varies for each of these cancers by certain demographic characteristics, such as race and age. METHODS: The authors examined high-quality data from 27 population-based cancer registries covering approximately 59% of the US population...
November 6, 2017: Cancer
https://www.readbyqxmd.com/read/29104417/pubic-hair-shaving-is-correlated-to-vulvar-dysplasia-and-inflammation-a-case-control-study
#10
Meike Schild-Suhren, Amr A Soliman, Eduard Malik
Objective: The risk factors for vulvar dysplasia and infections are not fully known. In this study, we aimed to investigate the correlation between pubic hair shaving and the occurrence of vulvar inflammation, dysplasia, and cancer. Methods: This study was performed between January 2013 and December 2016 in which a standardized questionnaire concerning genital hair shaving was administered to vulvar dysplasia and cancer patients and healthy participants. The presence of human papilloma virus (HPV) infection and the occurrence of genital inflammation were documented...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29094103/multidisciplinary-gynecologic-oncology-clinic-in-botswana-a-model-for-multidisciplinary-oncology-care-in-low-and-middle-income-settings
#11
Surbhi Grover, Sebathu Philip Chiyapo, Priya Puri, Mohan Narasimhamurthy, Babe Eunice Gaolebale, Neo Tapela, Doreen Ramogola-Masire, Mukendi K A Kayembe, Thabo Moloi, Ponatshego Andrew Gaolebale
Purpose: Cervical cancer is a major cause of mortality in low- and middle-income countries (LMICs) and the most common cancer diagnosed in women in Botswana. Most women present with locally advanced disease, requiring chemotherapy and radiation. Care co-ordination requires input from a multidisciplinary team (MDT) to deliver appropriate, timely treatment. However, there are limited published examples of MDT implementation in LMICs. Methods: In May 2015, a weekly MDT clinic for gynecologic cancer care was initiated at Botswana's national referral facility...
October 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/29090456/does-hpv-status-influence-survival-after-vulvar-cancer
#12
Christina Louise Rasmussen, Freja Laerke Sand, Marie Hoffmann Frederiksen, Klaus Kaae Andersen, Susanne K Kjaer
High-risk human papillomavirus (HPV) infection is essential in the carcinogenesis of a substantial part of anogenital and oropharyngeal cancers and has additionally been shown to be a possible predictive marker for survival, especially in oropharyngeal cancer. Studies examining the influence of HPV status on survival after vulvar cancer have been conflicting and limited by small study populations. Therefore, the aim of this review and meta-analysis was to examine whether HPV status influences survival after vulvar cancer, which, to our knowledge, has not been done before...
November 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29063590/the-prevalence-and-concordance-of-human-papillomavirus-infection-in-different-anogenital-sites-among-men-and-women-in-liuzhou-china-a-population-based-study
#13
Feixue Wei, Mingqiang Li, Xin Wu, Kai Yin, Jian Lan, Wei Sheng, Meng Guo, Shoujie Huang, Ying Wang, Yanping Li, Rongcheng Li, Yingying Su, Ting Wu, Jun Zhang, Ningshao Xia
Human papillomavirus (HPV) infection is the pathogenesis of anogenital cancers and genital warts in both men and women, whereas there is a scarcity of large studies focused on HPV prevalence in different anogenital sites of both sexes in the same population. From May to July 2014, 2309 men and 2378 women aged 18-55 were enrolled from a community in Liuzhou, China. Penis/glans penis/coronary sulcus (PGC) and perianal/anal canal (PA) specimens of men, and vaginal (VA), vulvar (VU) and PA specimens of women, were collected and genotyped for HPV...
October 24, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29037969/recurrent-vulvar-cancer-on-the-ankle
#14
Mohammad Alyafi, James Bentley
No abstract text is available yet for this article.
October 13, 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/29028665/gynecologic-cancer-in-hiv-infected-women-treatment-and-outcomes-in-a-multi-institutional-cohort
#15
Kimberly L Levinson, David J Riedel, Laureen S Ojalvo, Wesley Chan, Ana M Azngarita, Amanda N Fader, Anne F Rositch
OBJECTIVE: To evaluate gynecologic cancer treatments in Human Immunodeficiency Virus (HIV) infected women for adherence to National Comprehensive Cancer Network (NCCN) guidelines and to describe survival by adherence to guidelines. DESIGN: Beyond cervical cancer, there is little data on treatment and outcomes for these women. This is a retrospective cohort study of HIV infected women with gynecologic cancers. METHODS: HIV infected women with gynecologic cancers from 2000-2015 were identified at two urban, comprehensive cancer centers...
October 12, 2017: AIDS
https://www.readbyqxmd.com/read/28979888/high-dose-rate-salvage-interstitial-brachytherapy-a-case-based-guide-to-the-treatment-of-therapeutically-challenging-recurrent-vulvar-cancer
#16
Kelly Eileen Hughes, Christopher M McLaughlin, Emma C Fields
Vulvar cancer is a rare gynecological malignancy with incidence rates steadily increasing over the past 10 years. Despite aggressive treatment, recurrent disease is common. Vulvar cancer recurrence poses a significant therapeutic challenge as most patients have been previously treated with surgery and/or radiation limiting the options for additional treatment. There are no consensus guidelines for the treatment of recurrent disease. Current literature supports the use of salvage interstitial brachytherapy...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28979650/-urethral-ectropion-may-hide-a-carcinoma
#17
Mohammed Alae Touzani, Othmane Yddoussalah
The incidence of female urethral cancer is rare and accounts for 0.02% of all women's cancers. It is dominated by epidermoid carcinoma, which most commonly develops in the distal portion of the urethra, extending to inguinal lymph nodes. The diagnosis is confirmed in the distal forms on the basis of uretrocystoscopy with biopsy. Abdominopelvic MRI allows to determine tumor extension as well as its infiltration into tissues and peri-urethral organs. As in superficial tumors of the distal urethra, simple circumferential resection of the urethra associated with resection of the adjacent portion of the anterior surface of the vagina is sufficient...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28969759/sentinel-lymph-node-biopsy-procedures
#18
REVIEW
Valeria M Moncayo, Adina L Alazraki, Naomi P Alazraki, John N Aarsvold
Accurate staging of many cancers with no clinical evidence of lymph node involvement is often a critical component of the management of such cancers and is generally and historically accomplished by accurate pathological assessment of multiple nodes. Unfortunately, such assessment usually involves excision of the multiple nodes and can result in significant morbidities. Over the past half century, and particularly over the last quarter century, investigators have defined and refined the "sentinel lymph node(s)" concept and have developed and investigated sentinel lymph node biopsy (SLNB) procedures...
November 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28958732/long-term-outcome-after-resection-of-liver-metastases-from-squamous-cell-carcinoma
#19
Kiyohiko Omichi, Takashi Mizuno, Masayuki Okuno, Ching-Wei D Tzeng, Claudius Conrad, Yun Shin Chun, Thomas A Aloia, Jean-Nicolas Vauthey
BACKGROUND: Squamous cell carcinoma (SCC) liver metastases still remains a difficult challenge and the effectiveness of resection for SCC liver metastases is unclear. The aim of this study was to analyze long-term outcomes of surgically treated patients with SCC liver metastases. METHODS: The clinicopathological characteristics, overall survival (OS), and recurrence free survival (RFS) of all patients with SCC liver metastases resected between 1998 and 2015, were analyzed...
September 13, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28956458/9-valent-human-papillomavirus-vaccine-a-review-of-the-clinical-development-program
#20
Alain Luxembourg, Erin Moeller
The 9-valent human papillomavirus (9vHPV) vaccine covers the same HPV types (6/11/16/18) as the quadrivalent HPV (qHPV) vaccine and 5 additional cancer-causing types (31/33/45/52/58). Epidemiological studies indicate that the 9vHPV vaccine could prevent approximately 90% of cervical cancers, 70-85% of high-grade cervical dysplasia (precancers), 85-95% of HPV-related vulvar, vaginal, and anal cancers, and 90% of genital warts. Areas covered: Study design features and key findings from the 9vHPV vaccine clinical development program are reviewed...
October 9, 2017: Expert Review of Vaccines
keyword
keyword
2540
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"