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Osteo-Arthritis

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https://www.readbyqxmd.com/read/28856511/local-infiltration-analgesia-a-2-year-follow-up-of-patients-undergoing-total-hip-arthroplasty
#1
Ján Kuchálik, Anders Magnuson, Anders Lundin, Anil Gupta
PURPOSE: Local infiltration analgesia (LIA) is commonly used for postoperative pain management following total hip arthroplasty (THA). However, the long-term effects of the component drugs are unclear. The aim of our study was to investigate functional outcome, quality of life, chronic post-surgical pain, and adverse events in patients within 2 years of undergoing THA. METHODS: The study was a secondary analysis of data from a previous larger study. Eighty patients were randomized to receive either intrathecal morphine (Group ITM) or local infiltration analgesia (Group LIA) for pain management in a double-blind study...
August 30, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28765881/identification-of-differentially-expressed-micrornas-in-knee-anterior-cruciate-ligament-tissues-surgically-removed-from-patients-with-osteoarthritis
#2
Bin Li, Lunhao Bai, Peng Shen, Yue Sun, Zhizuo Chen, Yu Wen
The degradation of cruciate ligaments is frequently observed in degenerative joint diseases, such as osteo-arthritis (OA). The present study aimed to identify the differentially expressed microRNAs (miRNAs or miRs) in knee anterior cruciate ligament (ACL) tissues derived from patients with OA and in health subjects (non-OA). By using Affymetrix miRNA 4.0 microarrays, a total of 22 miRNAs (including let-7f-5p, miR-26b-5p and miR-146a-5p) were found to be upregulated, while 17 (including miR-18a-3p, miR-138-5p and miR-485-3p) were downregulated in the osteoarthritic ACL tissues (fold change ≥2, P-value <0...
October 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28653517/-cervical-pain-radiating-to-the-upper-limb
#3
I Bold, A Devriendt, E Maillart, A Noseda
A 31 years old male, HIV negative, with past history of sarcoidosis with articular and pulmonary involvement, without immuno-suppressive therapy, presents two years later with cervical pain radiating to the upper limb. Cervical imaging shows several para vertebral collections and lytic bone lesions. A diagnosis of tuberculous osteo-arthritis is established based on imaging and mycobacterial data.
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28462798/no-associations-between-self-reported-knee-joint-instability-and-radiographic-features-in-knee-osteoarthritis-patients-prior-to-total-knee-arthroplasty-a-cross-sectional-analysis-of-the-longitudinal-leiden-orthopaedics-outcomes-of-osteo-arthritis-study-loas
#4
Claudia S Leichtenberg, Jorit J L Meesters, Herman M Kroon, Suzan H M Verdegaal, Claire Tilbury, Joost Dekker, Rob G H H Nelissen, Thea P M Vliet Vlieland, Martin van der Esch
BACKGROUND: To describe the prevalence of self-reported knee joint instability in patients with pre-surgery knee osteoarthritis (OA) and to explore the associations between self-reported knee joint instability and radiological features. METHODS: A cross-sectional study including patients scheduled for primary Total Knee Arthroplasty (TKA). Self-reported knee instability was examined by questionnaire. Radiological features consisted of osteophyte formation and joint space narrowing (JSN), both scored on a 0 to three scale...
April 24, 2017: Knee
https://www.readbyqxmd.com/read/28163851/a-systematic-review-of-the-relationship-between-dystemprament-sue-mizaj-and-treatments-and-management-of-diseases-ilaj-and-eslah-e-mizaj
#5
REVIEW
Sepide Miraj, Samira Alesaeidi, Sara Kiani
BACKGROUND: Temperament refers to four different humors differentiating in individuals and, as a result, proposes specific therapy for diseases as well as special types of management (avoidance). OBJECTIVE: The aim of this study was to overview the relationship between dystemprament and treatment and management of diseases. METHODS: A computerized search of published articles was performed using PubMed, Scopus, Web of Science, and Medline databases as well as local sources from 1965 to 2016...
December 2016: Electronic Physician
https://www.readbyqxmd.com/read/28054496/tailoring-exercise-interventions-to-comorbidities-and-treatment-induced-adverse-effects-in-patients-with-early-stage-breast-cancer-undergoing-chemotherapy-a-framework-to-support-clinical-decisions
#6
Marike van der Leeden, Rosalie J Huijsmans, Edwin Geleijn, Mariëtte de Rooij, Inge R Konings, Laurien M Buffart, Joost Dekker, Martijn M Stuiver
PURPOSE: Delivery of exercise interventions to patients with early-stage breast cancer undergoing chemotherapy requires complex clinical decisions. The purpose of this study was to develop a framework to support clinical decisions for tailoring exercise interventions to common comorbidities and cancer treatment-induced adverse effects. METHOD: Tailored exercise prescriptions were developed in four steps, following the i3-S strategy. All steps were based on current best available evidence, complemented with expert opinions...
January 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27971683/medical-costs-attributable-to-obesity-in-working-osteo-arthritis-patients-in-the-us
#7
Y C Choi, S H Lee, Y J Lee, S Lee, S J Lim, D Suh
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27506570/treatment-of-displaced-supracondylar-humeral-fractures-in-children-by-humero-ulnar-external-fixation
#8
Aleksandra Bogdan, Jean Quintin, Frédéric Schuind
PURPOSE: Humero-ulnar external fixation has been proposed to treat complex supracondylar humeral fractures in children. It facilitates fracture reduction and reduces the risk of ulnar nerve lesion, which can occur after cross pinning. METHODS: In a ten year period, 28 children have been operated on in our centre by humero-ulnar external fixation, for Lagrange-Rigault stages III and IV supracondylar humeral fractures. The data about fracture management and early follow-up were obtained from our medical database...
November 2016: International Orthopaedics
https://www.readbyqxmd.com/read/26954784/biomarkers-of-osteo-arthritis
#9
EDITORIAL
Ali Mobasheri, Yves Henrotin
Arthritic diseases are a major cause of disability and morbidity, and cause an enormous burden for health and social care systems globally. Osteoarthritis (OA) is the most common form of arthritis. The key risk factors for the development of OA are age, obesity, joint trauma or instability. Metabolic and endocrine diseases can also contribute to the pathogenesis of OA. There is accumulating evidence to suggest that OA is a whole-organ disease that is influenced by systemic mediators, inflammaging, innate immunity and the low-grade inflammation induced by metabolic syndrome...
2015: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/26930022/prevalence-of-radiographic-knee-osteoarthritis-after-anterior-cruciate-ligament-reconstruction-with-or-without-meniscectomy-an-evidence-based-practice-article
#10
Jennifer S Ruano, Michael R Sitler, Jeffrey B Driban
Reference:  Claes S, Hermie L, Verdonk R, Bellemans J, Verdonk P. Is osteoarthritis an inevitable consequence of anterior cruciate ligament reconstruction? A meta-analysis. Knee Surg Sports Traumatol Arthrosc. 2013;21(9):1967-1976. CLINICAL QUESTION:   What is the prevalence of radiographic knee osteoarthritis (OA) at a mean follow-up equal to or greater than 10 years after autologous anterior cruciate ligament (ACL) reconstruction, with or without meniscectomy? DATA SOURCES:   The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines were used to conduct this meta-analysis...
June 2, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/26889468/early-joint-degeneration-and-antagonism-between-growth-factors-and-reactive-oxygen-species-is-non-surgical-management-possible
#11
Andrea Fabio Manunta, Pietro Zedde, Sebastiano Cudoni, Gianfilippo Caggiari, Gianfranco Pintus
PURPOSE: in pathological conditions such as osteo-arthritis (OA), overproduction of reactive oxygen species (ROS) may overwhelm the antioxidant defenses of chondrocytes, thus promoting oxidative stress and cell death. It can be hypothesized that increasing the antioxidant machinery of chondrocytes may prevent the age-associated progression of this disease. Growth factors (GFs) play an important role in promoting both the resolution of inflammatory processes and tissue repair. In view of these considerations, we set out to investigate the protective effect, against H2O2-induced oxidative cell death, potentially exerted by fluid drained from the joint postoperatively...
July 2015: Joints
https://www.readbyqxmd.com/read/26523194/-tuberculous-osteo-arthritis-of-the-ankle-and-spondylitis-a-rare-association
#12
Samia Frioui, Sonia Jemni
No abstract text is available yet for this article.
2015: Pan African Medical Journal
https://www.readbyqxmd.com/read/26378668/vertebral-osteomyelitis-and-septic-arthritis-associated-with-staphylococcus-hyicus-in-a-juvenile-peregrine-falcon-falco-peregrinus
#13
Kristina Maier, Dominik Fischer, Antje Hartmann, Olivia Kershaw, Ellen Prenger-Berninghoff, Helene Pendl, Martin J Schmidt, Michael Lierz
A 6-week-old, parent-reared peregrine falcon ( Falco peregrinus ) was presented with spastic hypertonus of its hind limbs of unknown origin and duration. Radiologic examination revealed smooth periosteal reactions ventrally at thoracic vertebrae 5 to 7. Contrast-enhanced computed tomography identified the swelling as inflammation; antibiotic, antimycotic, anti-inflammatory, and analgesic treatments were initiated, and vitamins and minerals were supplemented. Because the bird's condition did not improve after 10 days, it was euthanatized and submitted for postmortem examination...
September 2015: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/26346615/enterococcus-faecalis-endophthalmitis-as-a-metastatic-complication-of-hemodialysis-vascular-access-related-sepsis-a-case-report-and-review-of-the-literature
#14
REVIEW
Osman Zikrullah Sahin, Ekrem Kara, Tahir Belice, Teslime Ayaz, Serap Baydur Sahin, Cinar Ozturk, Safak Yildirim, Yavuz Metin, Tuncay Sahutoglu
Catheter and/or arteriovenous (A-V) graft-related bacteremia is an important cause of morbidity and mortality among hemodialysis (HD) patients. Endocarditis, septic arthritis, epidural abscess, septic embolism, and osteomyelitis are the most common complications of catheter and/or A-V graft-related bacteremia; however, endogenous endophthalmitis is rarely seen. To the best of our knowledge, Enterococcus faecalis is the first case report in this population. We hereby report a case of endogenous endophthalmitis caused by E...
July 2016: Hemodialysis International
https://www.readbyqxmd.com/read/26337792/serious-complications-from-staphylococcal-aureus-in-atopic-dermatitis
#15
REVIEW
Devika Patel, Marla N Jahnke
Colonization with Staphylococcal aureus is markedly more frequent in individuals with atopic dermatitis (AD) than in unaffected individuals. Chronic scratching leads to worsening of an existing defect in the epidermal barrier, which can allow S. aureus invasion into the bloodstream and subsequent systemic infections. We report two unusual cases of systemic illness in individuals with AD. One developed infective endocarditis followed by a stroke and the other developed septic arthritis and osteomyelitis. We performed an extensive literature review of reported systemic complications caused by S...
November 2015: Pediatric Dermatology
https://www.readbyqxmd.com/read/26325316/chitosan-coated-vancomycin-hydrochloride-liposomes-characterizations-and-evaluation
#16
Zhenlei Yang, Junli Liu, Jinhua Gao, Shilei Chen, Guihua Huang
The present work evaluated the feasibility of chitosan coated liposomes (c-Lips) for the intravenous delivery of vancomycin hydrochloride (VANH), a water-soluble antibiotic for the treatment of gram-positive bacterial infections like osteomyelitis, arthritis, endocarditis, pneumonia, etc. The objective of this research was to develop a suitable drug delivery system in vivo which could improve therapeutic efficacy and decrease side effects especially nephrotoxicity. Firstly, the vancomycin hydrochloride liposomes (VANH-Lips) were prepared by modified reverse phase evaporation method, then the chitosan wrapped vancomycin hydrochloride liposomes (c-VANH-Lips) nanosuspension was formulated by the method of electrostatic deposition...
November 10, 2015: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/26288520/osteoid-osteoma-masquerading-tubercular-arthritis-or-osteomyelitis-on-mri-case-series-and-review-of-literature
#17
Jatinder Pal Singh, Smita Srivastava, Dharmendra Singh
Magnetic resonance imaging (MRI) scans for osteoid osteoma could be misleading and can be misinterpreted as tuberculosis, especially when used as the principal modality of investigation. We retrospectively reviewed cases presenting to our institute for second opinion and selected six cases that were referred to our institute with a provisional diagnosis of tubercular arthritis or osteomyelitis and were identified to have osteoid osteoma. We reviewed the literature on typical and atypical clinical and radiological presentations of osteoid osteoma depending upon their location and present radiological features on MRI that should alert the radiologists toward a correct diagnosis...
July 2015: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/26276730/acute-neck-pain-caused-by-septic-arthritis-of-the-lateral-atlantoaxial-joint-with-subluxation-a-case-report
#18
Takashi Kobayashi, Naohisa Miyakoshi, Eiji Abe, Toshiki Abe, Kazuma Kikuchi, Yoichi Shimada
INTRODUCTION: Crystal-induced arthritis of the lateral atlantoaxial joint may be intimately involved in acute neck pain in the elderly. Patients typically have a good prognosis, and symptoms usually subside within a few weeks. On the other hand, septic arthritis of the lateral atlantoaxial joint requires early diagnosis and antibiotic treatment. Diagnostic delay is a risk factor for an unfavorable outcome of vertebral osteomyelitis. Even though septic arthritis of the lateral atlantoaxial joint is a very rare clinical entity, it is important to differentiate septic arthritis from crystal-induced arthritis...
August 15, 2015: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/26266184/is-mri-necessary-for-skeletal-evaluation-in-sickle-cell-disease
#19
Ankita Arun Sachan, Bhushan N Lakhkar, Bhavana B Lakhkar, Shivam Sachan
BACKGROUND: More than 50% of the world's cases of sickle cell anaemia are in India with an estimated population of 1.27 billion as against estimated world's population of 7.24 billion. AIM: MRI of 103 patients of sickle cell disease were evaluated to assess the skeletal changes in proven cases of sickle cell disease and to find the incidence of bony infarcts in such patients. The conversion of red marrow to yellow marrow in these patients were also studied. MATERIALS AND METHODS: Sickle cell patients with musculoskeletal pain as well as asymptomatic sickle cell patients were evaluated by MRI...
June 2015: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26255147/pin-tract-infection-of-operatively-treated-supracondylar-fractures-in-children-long-term-functional-outcomes-and-anatomical-study
#20
Shital N Parikh, Marios G Lykissas, Mazen Roshdy, Ronald C Mineo, Eric J Wall
PURPOSE: The purpose of our study was to determine the long-term functional outcomes of pin tract infection after percutaneous pinning of displaced supracondylar humeral fractures in children, and to evaluate the potential for intracapsular pin placement based on pin configuration in cadaveric elbows. METHODS: We conducted a retrospective review of all patients requiring percutaneous pinning in a single institution over a 19-year period. The functional outcome assessment consisted of a telephone interview using the Disabilities of the Arm, Shoulder and Hand (DASH)] Outcome Measure and the Patient-Rated Elbow Evaluation (PREE) questionnaires...
August 2015: Journal of Children's Orthopaedics
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