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https://www.readbyqxmd.com/read/29777605/ethics-and-or-aesthetics-reflections-on-cosmetic-surgery-for-adolescents
#1
Gianluca Montanari Vergallo, Enrico Marinelli, Simona Napoletano, Natale Mario Di Luca, Simona Zaami
Cosmetic surgery entails various ethical issues, even more so in cases involving adolescent patients. Cosmetic surgeons need to take into account how modern societies consider physical appearance an essential component of everyday life, as well as the vulnerability of youths and adolescents. For that reason, it is imperative to thoroughly assess the psychological and emotional states, in addition to the motivations, of minor patients. That goal can be achieved through the use of the DAS-59, (the Derriford Appearance Scale)1 , an effective and dependable tool devised to evaluate the psychological difficulties and distress experienced by people living with problems of appearance...
May 2018: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/29775962/preterm-birth-and-oxidative-stress-effects-of-acute-physical-exercise-and-hypoxia-physiological-responses
#2
Agnès Martin, Camille Faes, Tadej Debevec, Chantal Rytz, Grégoire Millet, Vincent Pialoux
Preterm birth is a global health issue that can induce lifelong medical sequela. Presently, at least one in ten newborns are born prematurely. At birth, preterm newborns exhibit higher levels of oxidative stress (OS) due to the inability to face the oxygen rich environment in which they are born into. Moreover, their immature respiratory, digestive, immune and antioxidant defense systems, as well as the potential numerous medical interventions following a preterm birth, such as oxygen resuscitation, nutrition, phototherapy and blood transfusion further contribute to high levels of OS...
May 1, 2018: Redox Biology
https://www.readbyqxmd.com/read/29775908/mirror-therapy-for-improving-lower-limb-motor-function-and-mobility-after-stroke-a-systematic-review-and-meta-analysis
#3
REVIEW
P Broderick, F Horgan, C Blake, M Ehrensberger, D Simpson, K Monaghan
BACKGROUND: Mirror therapy has been proposed as an effective intervention for lower limb rehabilitation post stroke. RESEARCH QUESTION: This systematic review with meta-analysis examined if lower limb mirror therapy improved the primary outcome measures of muscle tone and motor function and the secondary outcome measures balance characteristics, functional ambulation, walking velocity, passive range of motion (PROM) for ankle dorsiflexion and gait characteristics in patients with stroke compared to other interventions...
May 12, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29773979/efficient-coding-and-energy-efficiency-are-promoted-by-balanced-excitatory-and-inhibitory-synaptic-currents-in-neuronal-network
#4
Lianchun Yu, Zhou Shen, Chen Wang, Yuguo Yu
Selective pressure may drive neural systems to process as much information as possible with the lowest energy cost. Recent experiment evidence revealed that the ratio between synaptic excitation and inhibition (E/I) in local cortex is generally maintained at a certain value which may influence the efficiency of energy consumption and information transmission of neural networks. To understand this issue deeply, we constructed a typical recurrent Hodgkin-Huxley network model and studied the general principles that governs the relationship among the E/I synaptic current ratio, the energy cost and total amount of information transmission...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29772396/understanding-the-conceptualisation-of-risk-in-the-context-of-community-dementia-care
#5
Marissa Dickins, Dianne Goeman, Fleur O'Keefe, Steve Iliffe, Dimity Pond
Risk has become a ubiquitous presence in modern society. For individuals diagnosed with dementia this preoccupation with risk can affect their day-to-day life in many ways. Maintaining autonomy while balancing risks is a continual struggle not only for those living with the disease, but also their carers, family and health professionals. To understand how these different groups of individuals conceptualise the issue of risk for those living with dementia, 83 semi-structured interviews were conducted with people living with dementia, carers, older people without significant experience of dementia, and registered nurses, and staff from a community nursing organisation...
May 9, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29772197/getting-ras-ults-solving-molecular-promiscuity-through-microdomain-selective-targeting
#6
Steven A Connor, Yu Tian Wang
In this issue of Neuron, Zhang et al. (2018) report a powerful new method for probing subcellular microdomain-specific signaling in cellular function. Through a microdomain-targeting approach, they delineate how Ras-family GTPases balance signaling diversity with specificity required for various forms of hippocampal synaptic plasticity.
May 16, 2018: Neuron
https://www.readbyqxmd.com/read/29771750/injectable-nonsteroidal-anti-inflammatory-drugs-in-sport
#7
Matthew J Matava
OBJECTIVE: The primary objective of this article is to review the basic science of nonsteroidal anti-inflammatory drugs (NSAIDs), their clinical effects, indications, potential complications, and ethical issues associated with the use of injectable NSAIDs in the treatment of athletes. These objectives are presented taking into consideration the contemporaneous issues associated with the treatment of amateur and professional athletes. DATA SOURCES: A nonformal review of the published medical literature and lay media focusing on the use of injectable NSAIDs in athletes was used for this article...
May 10, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29770543/impairment-in-toileting-behavior-after-a-stroke
#8
Eri Kawanabe, Makoto Suzuki, Satoshi Tanaka, Shotaro Sasaki, Toyohiro Hamaguchi
AIM: Dependence for toileting is the most problematic aspect for patients after a stroke. However, the relative difficulty of each component of toileting and the predictors for independent performance of these activities are unknown. We investigated these issues in stroke patients using Boltzmann sigmoid and generalized linear modeling. METHODS: We carried out a cross-sectional correlation study, including 107 adult inpatients, hospitalized for a stroke. We assessed the activity components of toileting, as well as evaluated physical impairment using the Fugl-Meyer Assessment, impairments in balance using the Berg Balance Scale, cognitive impairments using the Mini-Mental State Examination and the presence or absence of unilateral spatial neglect or aphasia...
May 17, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29767089/using-probiotics-to-improve-swine-gut-health-and-nutrient-utilization
#9
REVIEW
Shengfa F Liao, Martin Nyachoti
To maintain a healthy gut is definitely key for a pig to digest and absorb dietary nutrients efficiently. A balanced microbiota (i.e., a healthy micro-ecosystem) is an indispensable constituent of a healthy gut. Probiotics, the live microorganisms which, when administered in adequate amounts, confer good health benefits onto the host, are a category of feed additives that can be used to replenish the gut microbial population while recuperating the host immune system. Besides their antitoxin and diarrhea reduction effects, dietary supplementation of probiotics can improve gut health, nutrient digestibilities and, therefore, benefit nutrient utilization and growth performance of pigs...
December 2017: Animal nutrition
https://www.readbyqxmd.com/read/29766480/-the-therapeutic-alliance-in-community-mental-health-services
#10
A Groenendijk, J Van Hecke
The treatment of severe mental illnesses is increasingly taking place in a domiciliary setting due to the deinstitutionalisation.<br/> AIM: Theoretical reflection on the influence of home treatment on the therapeutic alliance.<br/> METHOD: Qualitative review of possible effects of home treatment based on own experiences, the scientific literature, and recent handbooks on community mental health.<br/> RESULTS: The therapeutic relationship appears to be an important general factor in the outcomes of community mental health approaches...
2018: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/29766369/nutritional-issues-in-food-allergy
#11
REVIEW
Isabel J Skypala, Rebecca McKenzie
Diet and nutrition play an important role in the development and management of food allergy. The diet of expectant mothers can have an effect on their offspring in terms of allergic outcomes. A host of confounding factors may influence this, with a maternal diet rich in fruits and vegetables, fish, vitamin D-rich foods associated with a lower risk of allergic disease in their children. More surprisingly, the consumption of milk and butter has also been shown to have a protective effect, especially in a farm environment...
May 15, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29765379/-vitis-vinifera-l-fruit-diversity-to-breed-varieties-anticipating-climate-changes
#12
Antoine Bigard, Dargie T Berhe, Eleonora Maoddi, Yannick Sire, Jean-Michel Boursiquot, Hernan Ojeda, Jean-Pierre Péros, Agnès Doligez, Charles Romieu, Laurent Torregrosa
The wine industry is facing critical issues due to climate changes since production is established on very tight Genotype × Environment interaction bases. While, some cultivation practices may reduce adverse effects of abiotic stresses on the vines, e.g., the use of irrigation to mitigate drought, the deleterious impacts of warming on fruit development are difficult to manage. Elevated temperature alters grapevine fruit growth and composition, with a critical increase of the sugars/organic acids ratio. Select grapes with improved metabolite balances to offset high temperature effects is a valuable option to sustain viticulture...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29764323/swaps-and-chains-and-vouchers-oh-my-evaluating-how-saving-more-lives-impacts-the-equitable-allocation-of-live-donor-kidneys
#13
Evelyn M Tenenbaum
Live kidney donation involves a delicate balance between saving the most lives possible and maintaining a transplant system that is fair to the many thousands of patients on the transplant waiting list. Federal law and regulations require that kidney allocation be equitable, but the pressure to save patients subject to ever-lengthening waiting times for a transplant has been swinging the balance toward optimizing utility at the expense of justice. This article traces the progression of innovations created to make optimum use of a patient's own live donors...
March 2018: American Journal of Law & Medicine
https://www.readbyqxmd.com/read/29760119/spring-summer-net-community-production-new-production-particle-export-and-related-water-column-biogeochemical-processes-in-the-marginal-sea-ice-zone-of-the-western-antarctic-peninsula-2012-2014
#14
Hugh W Ducklow, Michael R Stukel, Rachel Eveleth, Scott C Doney, Tim Jickells, Oscar Schofield, Alex R Baker, John Brindle, Rosie Chance, Nicolas Cassar
New production (New P, the rate of net primary production (NPP) supported by exogenously supplied limiting nutrients) and net community production (NCP, gross primary production not consumed by community respiration) are closely related but mechanistically distinct processes. They set the carbon balance in the upper ocean and define an upper limit for export from the system. The relationships, relative magnitudes and variability of New P (from 15 NO3 - uptake), O2  : argon-based NCP and sinking particle export (based on the 238 U : 234 Th disequilibrium) are increasingly well documented but still not clearly understood...
June 28, 2018: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/29755169/interrater-reliability-of-three-versions-of-the-chedoke-arm-and-hand-activity-inventory
#15
Denise Johnson, Jocelyn E Harris, Paul Stratford, Julie Richardson
Purpose: The purpose of this study was to estimate the interrater reliability of three shortened versions of the Chedoke Arm and Hand Activity Inventory (CAHAI-7, CAHAI-8, CAHAI-9) when used with persons with acquired brain injury (ABI). The CAHAI is an assessment of upper limb function with high reliability in the stroke and ABI populations. In the stroke population, three shortened versions of the measure have established reliability. Clinicians report time constraints as a barrier to using standardized assessments; thus, establishing the reliability of the shortened versions of the CAHAI in the ABI population may increase the use of this measure...
2018: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/29754437/reduced-fiber-size-capillary-supply-and-mitochondrial-activity-in-constitutional-thinness-skeletal-muscle
#16
Bogdan Galusca, Julien Verney, Emmanuelle Meugnier, Yiin Ling, Pascal Edouard, Leonard Feasson, Marion Ravelojaona, Hubert Vidal, Bruno Estour, Natacha Germain
AIM: Constitutional thinness (CT) is a rare condition of natural low bodyweight, with no psychological issues, no marker of undernutrition and a resistance to weight gain. This study evaluated the skeletal muscle phenotype of CT women by comparison to a normal BMI control group. METHODS: 10 CT women (BMI< 17.5 kg/m2) and 10 female controls (BMI: 18.5-25 kg/m2) underwent metabolic and hormonal assessment along with muscle biopsies to analyse the skeletal muscular fibers pattern, capillarity, enzymes activities and transcriptomics...
May 13, 2018: Acta Physiologica
https://www.readbyqxmd.com/read/29752818/fluoxetine-uses-in-nociceptive-pain-management-a-promising-adjuvant-to-opioid-analgesics
#17
Mostafa M Hamdy, Mohamed M Elbadr, Ahmed Barakat
Fluoxetine, a commonly prescribed antidepressant, use in nociceptive pain management represent one of the unsettled issues of fluoxetine therapeutics. By reviewing the literature about fluoxetine's possible roles in this setting; those could be solitary antinociceptive effect, enhancement of acute morphine analgesia, blocking morphine tolerance development, and blocking dependence development and associated abstinence syndrome. In this study, we examined those four alleged roles of fluoxetine. Moreover, since effective alleviation of morphine tolerance, dependence, and abstinence syndrome represents one of the most challenging medical needs, we biochemically analyzed fluoxetine effect on these phenomena...
May 12, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29751660/striking-a-balance-a-qualitative-study-of-next-of-kin-participation-in-the-care-of-older-persons-in-nursing-homes-in-sweden
#18
Birgitta Wallerstedt, Lina Behm, Åsa Alftberg, Anna Sandgren, Eva Benzein, Per Nilsen, Gerd Ahlström
Most of the care in nursing homes is palliative in nature, as it is the oldest and the frailest people who live in nursing homes. The aim of this study was to explore next of kin's experiences of participating in the care of older persons at nursing homes. A qualitative design was used, based on semi-structured interviews with 40 next of kin, and analyzed using qualitative content analysis. An overarching theme emerged, a balancing act consisting of three categories: (1) visiting the nursing home; (2) building and maintaining relationships; and (3) gathering and conveying information...
May 11, 2018: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/29751589/a-cross-layer-optimized-opportunistic-routing-scheme-for-loss-and-delay-sensitive-wsns
#19
Xin Xu, Minjiao Yuan, Xiao Liu, Anfeng Liu, Neal N Xiong, Zhiping Cai, Tian Wang
In wireless sensor networks (WSNs), communication links are typically error-prone and unreliable, so providing reliable and timely data routing for loss- and delay-sensitive applications in WSNs it is a challenge issue. Additionally, with specific thresholds in practical applications, the loss and delay sensitivity implies requirements for high reliability and low delay. Opportunistic Routing (OR) has been well studied in WSNs to improve reliability for error-prone and unreliable wireless communication links where the transmission power is assumed to be identical in the whole network...
May 3, 2018: Sensors
https://www.readbyqxmd.com/read/29749272/fulvestrant-for-the-treatment-of-advanced-breast-cancer
#20
Sophie A Blackburn, Ruth M Parks, Kwokleung Cheung
The current issues with endocrine therapy for treatment of advanced breast cancer include balance of efficacy of therapy versus tolerability as well as hormone resistance. The efficacy of fulvestrant, a selective oestrogen receptor degrader (SERD), has been demonstrated in hormone receptor positive patients previously untreated or treated with hormonal therapy. Areas covered: This article discusses the journey of fulvestrant licensing, its efficacy in combination with other endocrine therapies and the future role it may have within breast cancer treatment...
May 11, 2018: Expert Review of Anticancer Therapy
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