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https://www.readbyqxmd.com/read/28436583/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#1
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
April 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28435755/comparison-of-primary-care-physician-reimbursement-rates-in-the-united-states
#2
Nathan Riley, Kelley Withy, Kevin Rogers, Ragan DuBose-Morris, Tiffany Kurozawa
With a growing shortage of physicians, particularly primary care physicians, the issue of adequate pay in Hawai'i is increasingly important. Anecdotal reports of low pay in Hawai'i have rarely been substantiated. Data from FAIR Health, a company that tracks private insurance reimbursement rates, is compared across the United States (US) for the CPT code 99213. In addition, FAIR Health and Medicare rates are compared for cities with both similar and disparate cost of living to Hawai'i. Hawai'i is in the second lowest quintile for payment in the US for private insurances, and providers are reimbursed significantly lower than in cities with similar cost of living by both Medicare and private insurances...
March 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28434723/labeling-strategies-to-overcome-the-problem-of-niche-markets-for-sustainable-milk-products-the-example-of-pasture-raised-milk
#3
S Kühl, B Gassler, A Spiller
Pasture-raised milk is gaining in importance in some European countries and in the United States. The production of pasture-raised milk is linked to higher costs, as the milk is normally collected and processed separately from conventional barn milk. This could hinder the production of sustainable milk products. We discuss alternative labeling strategies that allow the mixing of pasture-raised (sustainable) and conventional milk to reduce costs and break free from the current niche market. The lower price would allow for more pasture-raised milk to be produced and enter the mainstream market...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28434390/how-preferences-for-continuity-and-access-differ-between-multimorbidity-and-healthy-patients-in-a-team-care-setting
#4
Katherine M Ehman, Mark Deyo-Svendsen, Zachary Merten, Anne Marie Kramlinger, Gregory M Garrison
INTRODUCTION: Team-based care has become an essential part of modern medical practice. Patient-centered medical homes often struggle to balance the dual competing goals of acute access and continuity of care. Multimorbidity patients may value continuity more than healthy patients, and thus may prefer to wait to see their primary care physician (PCP). METHODS: A total of 1700 randomly selected healthy adults and multimorbidity patients were asked to rate satisfaction with care and presented with 4 acute and 4 chronic scenarios to choose an access and continuity preference in an anonymous mailed survey...
April 1, 2017: Journal of Primary Care & Community Health
https://www.readbyqxmd.com/read/28432419/-driving-and-dementia-an-issue-for-general-practice
#5
REVIEW
Verena Leve, Katharina Ilse, Marie Ufert, Stefan Wilm, Michael Pentzek
BACKGROUND: With most forms of dementia, the risk of road traffic accidents increases with disease progression. Addressing the issue of fitness to drive at an early stage can help to reduce driving-related risks and simultaneously preserve mobility. General practitioners (GPs) are central contact persons for dementia patients and their relatives in medical and psychosocial matters, and also play a key role in addressing the issue of driving safety. OBJECTIVE: Identification of relevant aspects of managing fitness to drive in dementia, as well as of support requirements for German general practice...
April 21, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28431202/pharmacological-interventions-for-acute-pancreatitis
#6
REVIEW
Elisabetta Moggia, Rahul Koti, Ajay P Belgaumkar, Federico Fazio, Stephen P Pereira, Brian R Davidson, Kurinchi Selvan Gurusamy
BACKGROUND: In people with acute pancreatitis, it is unclear what the role should be for medical treatment as an addition to supportive care such as fluid and electrolyte balance and organ support in people with organ failure. OBJECTIVES: To assess the effects of different pharmacological interventions in people with acute pancreatitis. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL, 2016, Issue 9), MEDLINE, Embase, Science Citation Index Expanded, and trial registers to October 2016 to identify randomised controlled trials (RCTs)...
April 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28430820/cardiovascular-safety-of-tiotropium-respimat-vs-handihaler-in-the-routine-clinical-practice-a-population-based-cohort-study
#7
Francesco Trotta, Stefania Spila-Alegiani, Roberto Da Cas, Maja Rajevic, Valentino Conti, Mauro Venegoni, Mariangela Rossi, Giuseppe Traversa
The cardiovascular safety of tiotropium Respimat formulation in the routine clinical practice is still an open issue. Our aim was to compare the risk of acute myocardial infarction and heart rhythm disorders in incident users of either tiotropium Respimat or HandiHaler. The study population comprises patients aged ≥45 years, resident in two Italian regions with a first prescription of tiotropium (HandiHaler or Respimat) between 01/07/2011-30/11/2013. The cohort was identified through the database of prescriptions reimbursed by the Italian National Health Service...
2017: PloS One
https://www.readbyqxmd.com/read/28428350/targeted-inactivation-of-copper-transporter-atp7b-in-hepatocytes-causes-liver-steatosis-and-obesity-in-mice
#8
Abigael Muchenditsi, Haojun Yang, James P Hamilton, Lahari Koganti, Franck Housseau, Lisa Aronov, Hongni Fan, Hannah Pierson, Ashima Bhattacharjee, Robert C Murphy, Cynthia L Sears, James J Potter, Clavia Ruth Wooton-Kee, Svetlana Lutsenko
The copper transporter ATP7B is essential for mammalian copper homeostasis. Mutations in ATP7B result in copper accumulation, especially in the liver, and cause Wilson disease (WD). The major role of hepatocytes in WD pathology is firmly established. It is less certain whether the excess Cu in hepatocytes is solely responsible for development of WD. To address this issue, we generated a mouse strain for Cre-mediated deletion of Atp7b and inactivated Atp7b selectively in hepatocytes. Atp7bΔ(Hep) mice accumulate copper in the liver, have elevated urinary copper, lack holo-ceruloplasmin, but show no liver disease for up to 30 weeks...
April 20, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/28422062/cross-layer-design-for-optimizing-transmission-reliability-energy-efficiency-and-lifetime-in-body-sensor-networks
#9
Xi Chen, Yixuan Xu, Anfeng Liu
High transmission reliability, energy efficiency, and long lifetime are pivotal issues for wireless body area networks (WBANs. However, these performance metrics are not independent of each other, making it hard to obtain overall improvements through optimizing one single aspect. Therefore, a Cross Layer Design Optimal (CLDO) scheme is proposed to simultaneously optimize transmission reliability, energy efficiency, and lifetime of WBANs from several layers. Firstly, due to the fact that the transmission power of nodes directly influences the reliability of links, the optimized transmission power of different nodes is deduced, which is able to maximize energy efficiency in theory under the premise that requirements on delay and jitter are fulfilled...
April 19, 2017: Sensors
https://www.readbyqxmd.com/read/28421070/interplay-of-regulatory-t-cell-and-th17-cells-during-infectious-diseases-in-humans-and-animals
#10
REVIEW
Sharvan Sehrawat, Barry T Rouse
It is now clear that the outcome of an inflammatory process caused by infections depends on the balance of responses by several components of the immune system. Of particular relevance is the interplay between regulatory T cells (Tregs) and CD4(+) T cells that produce IL-17 (Th17 cells) during immunoinflammatory events. In addition to discussing studies done in mice to highlight some unresolved issues in the biology of these cells, we emphasize the need to include outbred animals and humans in analyses. Achieving a balance between Treg and Th17 cells responses represents a powerful approach to control events during immunity and immunopathology...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28420979/evidence-for-a-selectively-regulated-prioritization-shift-depending-on-walking-situations-in-older-adults
#11
Dina Salkovic, Markus A Hobert, Carolin Bellut, Florian Funer, Sarah Renno, Linda Haertner, Sandra E Hasmann, Jana Staebler, Johanna Geritz, Ulrike Suenkel, Andreas J Fallgatter, Gerhard W Eschweiler, Daniela Berg, Walter Maetzler
Background: Older adults have increased risks of balance issues and falls when walking and performing turns in daily situations. Changes of prioritization during different walking situations associated with dual tasking may contribute to these deficits. The objective of this study was therefore to investigate whether older adults demonstrate changes of prioritization during different walking paths. Methods: In total, 1,054 subjects with an age range from 50 to 83 years were selected from the first follow-up visit of the TREND (Tuebinger evaluation of Risk factors for Early detection of Neurodegenerative Disorders) study...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28418280/twenty-first-century-pathologists-advocacy
#12
Timothy Craig Allen
Pathologists' advocacy plays a central role in the establishment of continuously improving patient care quality and patient safety, and in the maintenance and progress of pathology as a profession. Pathology advocacy's primary goal is the betterment of patient safety and quality medical care; however, payment is a necessary and appropriate component to both, and has a central role in advocacy. Now is the time to become involved in pathology advocacy; the Medicare Access and Children's Health Insurance Program (CHIP) Reauthorization Act of 2015 (MACRA) and the Protecting Access to Medicare Act of 2014 (PAMA) are two of the most consequential pieces of legislation impacting the pathology and laboratory industry in the last 20 years...
April 18, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/28416723/the-origin-of-inner-solar-system-water
#13
REVIEW
Conel M O'D Alexander
Of the potential volatile sources for the terrestrial planets, the CI and CM carbonaceous chondrites are closest to the planets' bulk H and N isotopic compositions. For the Earth, the addition of approximately 2-4 wt% of CI/CM material to a volatile-depleted proto-Earth can explain the abundances of many of the most volatile elements, although some solar-like material is also required. Two dynamical models of terrestrial planet formation predict that the carbonaceous chondrites formed either in the asteroid belt ('classical' model) or in the outer Solar System (5-15 AU in the Grand Tack model)...
May 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28414294/salt-and-water-not-so-simple
#14
Mark L Zeidel
It has long been viewed that the maintenance of osmotic balance in response to high salt intake is a passive process that is mediated largely by increased water consumption to balance the salt load. Two studies in this issue of the JCI challenge this notion and demonstrate that osmotic balance in response to high salt intake involves a complex regulatory process that is influenced by hormone fluctuation, metabolism, food consumption, water intake, and renal salt and water excretion. Rakova et al. report the unexpected observation that long-term high salt intake did not increase water consumption in humans but instead increased water retention...
April 17, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28411190/the-evolutionary-origins-of-antagonistic-neurotrophin-signaling
#15
Austin B Keeler, Christopher D Deppmann
A competitive balance between constructive and destructive developmental cues governs both the form and function of the vertebrate nervous system. In this issue, Foldi et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607098) explore the evolutionary origins of these cues and report that in Drosophila melanogaster pro- and mature neurotrophins are capable of inducing death and survival pathways, respectively, by binding Toll receptor family members, which then recruit distinct sets of effector proteins...
April 14, 2017: Journal of Cell Biology
https://www.readbyqxmd.com/read/28409187/thermodynamic-characterisation-of-urban-nocturnal-cooling
#16
Zhi-Hua Wang, Qi Li
Nocturnal cooling of urban areas governs the evolution of thermal state and many thermal-driven environmental issues in cities, especially those suffer strong urban heat island (UHI) effect. Advances in the fundamental understanding of the underlying physics of nighttime UHI involve disentangling complex contributing effects and remains an open challenge. In this study, we develop new numerical algorithms to characterize the thermodynamics of urban nocturnal cooling based on solving the energy balance equations for both the landscape surface and the overlying atmosphere...
April 2017: Heliyon
https://www.readbyqxmd.com/read/28405988/a-study-of-salt-and-fat-consumption-pattern-in-regional-indian-diet-among-hypertensive-and-dyslipidemic-patients-script-study
#17
Dayanand Kumbla, Mala Dharmalingam, Kalpesh Dalvi, Saumitra Ray, Mahesh K Shah, Sanjay Gupta, S Sadhanandham, A K Ajmani, Sanjay Nag, Srinivas Murthy, Mohana Murugan, Abhijit Trailokya, Tushar Fegade
BACKGROUND: Cardiovascular diseases are leading cause of mortality and morbidity. There is an increasing prevalence of hypertension and dyslipidemia due to globalization and adoption of westernized dietary habits in India. These transitions are manifest in dietary patterns and health outcomes. OBJECTIVE: To study the dietary salt and fat intake among patients diagnosed with hypertension and dyslipidemia in India. METHODS: SCRIPT study was a pilot exploratory, cross-sectional, observational, descriptive, multi-center study...
December 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28403749/cluster-success-fmri-inferences-for-spatial-extent-have-acceptable-false-positive-rates
#18
Scott D Slotnick
In an editorial (this issue), I argued that Eklund, Nichols, and Knutsson's 'null data' reflected resting-state/default network activity that inflated their false-positive rates. Commentaries on that paper were received by Nichols, Eklund, and Knutsson (this issue), Hopfinger (this issue), and Cunningham and Koscik (this issue). In this author response, I consider these commentaries. Many issues stemming from Nichols et al. are identified including: (1) Nichols et al. did not provide convincing arguments that resting-state fMRI data reflect null data...
April 19, 2017: Cognitive Neuroscience
https://www.readbyqxmd.com/read/28402414/inter-sectoral-transfer-of-the-food-for-life-settings-framework-in-england
#19
Selena Gray, Matthew Jones, Robin Means, Judy Orme, Hannah Pitt, Debra Salmon
Organisational settings such as schools, workplaces and hospitals are well recognised as key environments for health promotion. Whilst there is extensive literature on specific types of settings, little empirical research has investigated the transfer of frameworks between sectors. This study analyses Food for Life, an England-wide healthy and sustainable food programme that evolved in schools and is being adapted for children's centres, universities, care homes, and hospital settings. Following a case study design, we interviewed 85 stakeholders in nine settings...
April 11, 2017: Health Promotion International
https://www.readbyqxmd.com/read/28402293/influence-of-relative-air-water-flow-velocity-on-oxygen-mass-transfer-in-gravity-sewers
#20
Lucie Carrera, Fanny Springer, Gislain Lipeme-Kouyi, Pierre Buffiere
Problems related to hydrogen sulfide may be serious for both network stakeholders and the public in terms of health, sustainability of the sewer structure and urban comfort. H2S emission models are generally theoretical and simplified in terms of environmental conditions. Although air transport characteristics in sewers must play a role in the fate of hydrogen sulfide, only a limited number of studies have investigated this issue. The aim of this study was to better understand H2S liquid to gas transfer by highlighting the link between the mass transfer coefficient and the turbulence in the air flow and the water flow...
April 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
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