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Mosarrat J Qureshi, Manoj Kumar
BACKGROUND: Providing effective positive pressure ventilation is considered to be the single most important component of successful neonatal resuscitation. Ventilation is frequently initiated manually with bag and face mask (BMV) followed by endotracheal intubation if respiratory depression continues. These techniques may be difficult to perform successfully resulting in prolonged resuscitation or neonatal asphyxia. The laryngeal mask airway (LMA) may achieve initial ventilation and successful resuscitation faster than a bag-mask device or endotracheal intubation...
March 15, 2018: Cochrane Database of Systematic Reviews
Marcin Lipski, Chris R Abbiss, Kazunori Nosaka
PURPOSE: This study compared cardio-pulmonary responses between incremental concentric and eccentric cycling tests, and examined factors affecting the maximal eccentric cycling capacity. METHODS: On separate days, nine men and two women (32.6 ± 9.4 years) performed an upright seated concentric (CON) and an eccentric (ECC) cycling test, which started at 75 W and increased 25 W min-1 until task failure. Gas exchange, heart rate (HR) and power output were continuously recorded during the tests...
February 20, 2018: European Journal of Applied Physiology
Annelies van Zwol, Neelke B C Oosterloo, Cartijn T de Betue, Ad Bogers, Inge I de Liefde, Nicolaas E P Deutz, Koen F M Joosten
BACKGROUND AND AIMS: Children undergoing cardiac surgery with cardio pulmonary bypass often receive glucocorticoids to reduce the systemic inflammatory response. Glucocorticoids stimulate protein breakdown and increase amino acid availability. We studied whether glucocorticoid treatment influences the availability of amino acids, specifically those involved in the nitric oxide pathway. METHODS: We prospectively studied 49 children with congenital heart disease undergoing cardiac surgery...
February 2018: Clinical Nutrition ESPEN
Julia Hock, Barbara Reiner, Rhoia C Neidenbach, Renate Oberhoffer, Alfred Hager, Peter Ewert, Jan Müller
OBJECTIVE: Children and adolescents with an univentricular heart after total cavopulmonary connection (TCPC) have functional impairments. This study assesses health-related physical fitness (HRPF) and exercise capacity, as well as their relation to health-related quality of life (HRQoL) in patients with an univentricular heart after total-pulmonary connection (TCPC). PATIENTS AND METHODS: Between July 2014 and October 2016 a total of 78 children and adolescents with TCPC (12...
March 15, 2018: International Journal of Cardiology
Aleksandra Penezić, Roberta Moriano, Marija Spasić, Duško Ćirović
Dirofilaria immitis causes a severe and life-threatening cardio-pulmonary disease in Europe, Asia, Africa, and the Americas; also, zoonotic infections have been reported. This parasitic vector-borne disease is mostly common in domestic and wild canids and felids. Here, we present a rare finding of this roundworm in the heart of a Eurasian otter (Lutra lutra). Four mature specimens of D. immitis were found in the right ventricle of the heart. Necropsy was performed after the animal was found road-killed in Eastern Serbia, close to the Danube River...
January 26, 2018: Parasitology Research
Segura Melgarejo Francisca, Pardo Ríos Manuel, Vera Catalán Tomás, Juguera Rodríguez Laura, Pérez Alonso Nuria, Leal Costa César, Martínez Riquelme Carolina, López Ayuso Belén
INTRODUCTION: Currently, no system completely evaluates the quality of cardio pulmonary resusciation. METHODS: A cross-sectional, prospective, longitudinal study using Delphi methodology was performed in three phases: preparatory, consultation and consensus. The validation was made by a prospective longitudinal study using the tool in the evaluation of 11 videos to determine the intra-class correlation coefficient (ICC) and the intra-subject (ICC-Initial), the latter repeated at four weeks (ICC-Final)...
January 20, 2018: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
Dane E Anderson, Aniruddh D Patel
AIM: The neonatal intensive care unit (NICU) provides life-saving medical care for an increasing number of newborn infants each year. NICU care, while lifesaving, does have attendant consequences which can include repeated activation of the stress response and reduced maternal interaction, with possible negative long-term impacts on brain development. Here we present a neuroscientific framework for considering the impact of music on neurodevelopment in the NICU of infants born preterm and evaluate current literature on the use of music with this population to determine what is most reliably known of the physiological effects of music interventions...
January 24, 2018: Developmental Medicine and Child Neurology
Michaela B Rehman, Rodrigue Garcia, Luc Christiaens, Elisa Larrieu-Ardilouze, Luke S Howard, Petros Nihoyannopoulos
BACKGROUND: Right ventricular function is the major determinant of morbidity and mortality in pulmonary arterial hypertension (PAH). The ESC risk assessment strategy for PAH is based on clinical status, exercise testing, NTproBNP, imaging and haemodynamics but does not include right ventricular function. Our aims were to test the power of resting echocardiographic measurements to classify PAH patients according to ESC exercise testing risk stratification cut-offs and to determine if the classification power of echocardiographic parameters varied in chronic thrombo-embolic pulmonary hypertension (CTEPH)...
January 17, 2018: International Journal of Cardiology
Emmanuel Charbonney, Stéphane Delisle, Dominique Savary, Gilles Bronchti, Marceau Rigollot, Adrien Drouet, Bilal Badat, Paul Ouellet, Patrice Gosselin, Alain Mercat, Laurent Brochard, Jean-Christophe M Richard
BACKGROUND: Studying ventilation and intrathoracic pressure (ITP) induced by chest compressions (CC) during Cardio Pulmonary Resuscitation is challenging and important aspects such as airway closure have been mostly ignored. We hypothesized that Thiel Embalmed Cadavers could constitute an appropriate model. METHODS: We assessed respiratory mechanics and ITP during CC in 11 cadavers, and we compared it to measurements obtained in 9 out-of-hospital cardiac arrest patients and to predicted values from a bench model...
January 6, 2018: Resuscitation
Samad Ghaffari, Nariman Sepehrvand, Leili Pourafkari, Reza Hajizadeh, Elnaz Javanshir, Mehdi Nadiri, Nader D Nader
PURPOSE: We aimed to investigate the factors that are associated with increased cardiac troponin I (cTnI) leakage in the acute pulmonary embolism (PTE) setting and their alignment with patient outcome. METHODS: Adult patients with a diagnosis of PTE were enrolled in this prospective cohort study. The primary endpoint of interest was major adverse cardio-pulmonary events (MACPE), defined as the composite of in-hospital all-cause mortality, need for thrombolysis and mechanical ventilation and surgical embolectomy during index hospitalization...
April 2018: Journal of Critical Care
Robert A Berg, Robert M Sutton, Ron W Reeder, John T Berger, Christopher J Newth, Joseph A Carcillo, Patrick S McQuillen, Kathleen L Meert, Andrew R Yates, Rick E Harrison, Frank W Moler, Murray M Pollack, Todd C Carpenter, David L Wessel, Tammara L Jenkins, Daniel A Notterman, Richard Holubkov, Robert F Tamburro, J Michael Dean, Vinay M Nadkarni
Background -Based on laboratory cardiopulmonary resuscitation (CPR) investigations and limited adult data demonstrating that survival depends on attaining adequate arterial diastolic blood pressure (DBP) during CPR, American Heart Association recommends using BP to guide pediatric CPR. However, evidence-based BP targets during pediatric CPR remain an important knowledge gap for CPR guidelines. Methods -All children ≥37 weeks gestation and <19 years old in Collaborative Pediatric Critical Care Research Network intensive care units with chest compressions for ≥1 minute and invasive arterial blood pressure monitoring prior to and during CPR between July 1, 2013 and June 31, 2016 were included...
December 26, 2017: Circulation
Ahmer M Hameed, Ray Miraziz, David B Lu, Neil Warwick, Ali El-Ayoubi, Heather Burns, Yi Vee Chew, Ross Matthews, Greg O'Grady, Lawrence Yuen, Natasha Rogers, Henry C Pleass, Wayne J Hawthorne
BACKGROUND: The ongoing supply-demand gap with respect to donor kidneys for transplantation necessitates the increased use of higher kidney donor profile index and/or donation after circulatory death (DCD) kidneys. Machine perfusion (MP) preservation has become increasingly popular as a means to preserve such organs. Human data regarding normothermic kidney MP (NMP) is in its infancy, and such a system has not been established in the Australasian clinical setting. METHODS: Modified cardio-pulmonary bypass technology was utilized to develop a viable NMP kidney perfusion system using a porcine DCD model...
December 14, 2017: ANZ Journal of Surgery
Payam Heydari, Sakineh Varmazyar, Ali Safari Variani, Fariba Hashemi, Seyed Sajad Ataei
Background and aim: Test of maximal oxygen consumption is the gold standard for measuring cardio-pulmonary fitness. This study aimed to determine correlation of Gerkin, Queen's College, George, and Jackson methods in estimating maximal oxygen consumption, and demographic factors affecting maximal oxygen consumption. Methods: This descriptive cross-sectional study was conducted in a census of medical emergency students (n=57) in Qazvin University of Medical Sciences in 2016...
October 2017: Electronic Physician
Geert M Verleden, Lieven Dupont, Jonas Yserbyt, Veronique Schaevers, Dirk Van Raemdonck, Arne Neyrinck, Robin Vos
Lung transplantation remains the ultimate treatment option for selected patients with end-stage (cardio) pulmonary disease. Given the current organ shortage, it is without any doubt that careful selection of potential transplant candidates is essential as this may greatly influence survival after the procedure. In this paper, we will review the current guidelines for referral and listing of lung transplant candidates in general, and in more depth for the specific underlying diseases. Needless to state that these are not absolute guidelines, and that decisions depend upon center's activity, waiting list, etc...
September 2017: Journal of Thoracic Disease
George Latsios, George Mpompotis, Kostas Tsioufis, Kostas Toutouzas, Emmanouil Skalidis, Andreas Synetos, Dimosthenis Avramidis, Dimitris Tousoulis
BACKGROUND/AIMS: The incidence of cardiac (cardiopulmonary) arrest (CA) in the Catheterization Laboratory (Cath Lab) is not common. However, not only does it happen occasionally but also its frequency tends to increase with the increase in the overall number and complexity of interventions performed by interventional cardiologists. METHODS: Therefore, certified knowledge and application of the advanced life support (ALS) protocols by trained Cath Lab staff is imperative in many countries by local hospital standards and law...
December 5, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
T M Berghaus, J Kutsch, C Faul, W von Scheidt, M Schwaiblmair
BACKGROUND: N-terminal pro-brain-type natriuretic peptide (NT-proBNP) is currently used as a surrogate marker for disease severity in pulmonary hypertension (PH). However, NT-proBNP tends to have a high variability and may insufficiently correlate with hemodynamics and exercise capacity. METHODS: To investigate the association of NT-proBNP with hemodynamics and cardio-pulmonary exercise testing (CPET) in 84 therapy-naive patients with precapillary PH. RESULTS: NT-proBNP levels were significantly correlated with hemodynamics and CPET parameters except for cardiac index, diffusion capacity, PaO2 at peak exercise, and peak minute ventilation...
December 4, 2017: BMC Pulmonary Medicine
Othmar Moser, Max L Eckstein, Olivia McCarthy, Rachel Deere, Stephen C Bain, Hanne L Haahr, Eric Zijlstra, Richard M Bracken
Background: To explore the impact of glycaemic control (HbA1c ) on functional capacity during cardio-pulmonary exercise testing in people with type 1 diabetes. Methods: Sixty-four individuals with type 1 diabetes (age: 34 ± 8 years; 13 females, HbA1c : 7.8 ± 1% (62 ± 13 mmol/mol), duration of diabetes: 17 ± 9 years) performed a cardio-pulmonary cycle ergometer exercise test until volitional exhaustion. Stepwise linear regression was used to explore relationships between HbA1c and cardio-respiratory data with p ≤ 0...
2017: Diabetology & Metabolic Syndrome
Oliwia Glogowska, Maciej Glogowski, Sebastian Szmit
Introduction: The frequency of postoperative complications after thoracic surgery remains high. Rehabilitation may become a procedure characterized by a high cost-effectiveness ratio. The aim of the study was to determine the independent importance of intensive rehabilitation in patients with lung tumors treated by thoracic surgery. Material and methods: The prospective observational study included two groups of patients: 187 patients treated according to the historical scheme including thoracic surgery without specific exercises improving cardio-pulmonary capacity, and 215 patients treated in agreement with the innovative algorithm of perioperative intensive physiotherapy until discharge from hospital...
October 2017: Archives of Medical Science: AMS
Bartłomiej Perek, Sylwia Sławek, Agnieszka Malińska, Izabela Katyńska, Mateusz Puślecki, Bogumiła Szymak-Pawełczyk, Michał Nowicki, Marek Jemielity
Introduction: Aortic valve replacement (AVR) with a mechanical prosthesis is not free from late complications. Aim: To evaluate the prevalence of subclinical hemolysis after AVR with On-X prostheses and assess its impact on long-term outcomes. Material and methods: The prospective study included 84 consecutive patients aged 58.3 ±10.3 years who underwent AVR. They were retrospectively split into group H ( n = 12; 14.3%) with prosthesis-related subclinical hemolysis and a control group (C; n = 72; 85...
September 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
Yasuaki Koyama, Yoshiaki Inoue, Shuhei Hisago, Aiki Marushima, Keiichi Hagiya, Yuichiro Yamasaki, Yuki Enomoto, Nobutake Shimojo, Satoru Kawano, Taro Mizutani
BACKGROUND: The neurological prognosis is poor for patients suffering from out-of-hospital cardiac arrest (OHCA), in the absence of bystander cardio pulmonary resuscitation (CPR), and showing asystole as the initial waveform. However, such patients have the potential of resuming social activity if cerebral tissue oxygen saturation can be preserved. CASE PRESENTATION: We recently encountered a 60-year-old man who had suffered an OHCA in the absence of bystander CPR, and who successfully resumed complete social activity despite initial asystole and requiring at least 75min of chest compressions before return of spontaneous circulation (ROSC)...
November 13, 2017: American Journal of Emergency Medicine
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