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Noninvasive fat reduction

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https://www.readbyqxmd.com/read/29210446/quantification-of-noninvasive-fat-reduction-a-systematic-review
#1
Sogyong L Auh, Sanjana Iyengar, Alexandra Weil, Diana Bolotin, Todd V Cartee, Jeffrey S Dover, Ian A Maher, Joseph F Sobanko, Joel L Cohen, Emily Poon, Murad Alam
BACKGROUND AND OBJECTIVE: Noninvasive fat reduction appears effective, but there are various methods for quantifying changes. The objective of this review is to assess comparative utility measures of subcutaneous fat. STUDY DESIGN/MATERIALS AND METHODS: Articles describing noninvasive fat reduction were searched using MEDLINE, EMBASE, CINAHL and Scopus electronic databases on two dates (January 28, 2014 and February 16, 2016). Titles of studies and abstracts were screened for eligibility...
December 6, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29205814/immediate-effect-and-safety-of-hifu-single-treatment-for-male-subcutaneous-fat-reduction
#2
Fernanda Guth, Shanna Bitencourt, Cícero Bedinot, Giovana Sinigaglia, João Alberto Fioravante Tassinary
BACKGROUND: The increasing search for procedures for fat reduction is related to dissatisfaction with body shape. High-intensity focused ultrasound (HIFU) has been proven effective in body sculpting when used noninvasively to reduce subcutaneous fat and improve body contour. AIMS: This study aimed to evaluate the immediate effect and safety of HIFU single treatment for male localized fat and body remodeling. PATIENTS/METHODS: Twenty-four male subjects (18 to 59 years old) with BMI ≤ 30 kg/cm² and at least 2 cm of abdominal fat received a single HIFU treatment session...
December 4, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29188163/notalgia-paresthetica-a-novel-approach-to-treatment-with-cryolipolysis
#3
REVIEW
Philip R Cohen
Notalgia paresthetica, a neurosensory syndrome that typically occurs on the upper back, has multiple clinical symptoms with variable degrees of expression in each individual afflicted with the condition. The involved site is usually hyperpigmented and is associated with burning, coldness, hypoesthesia, increased pain, pruritus and/or tingling. In the affected area, the number of nerve fibers may be increased and the cutaneous sensory nerves are altered secondary to localized impingement, central injury, or both...
September 28, 2017: Curēus
https://www.readbyqxmd.com/read/29125214/treating-multiple-body-parts-for-skin-laxity-and-fat-deposits-using-a-novel-focused-radiofrequency-device-with-an-ultrasound-component-safety-and-efficacy-study
#4
Suneel Chilukuri, Dominique Denjean, Linda Fouque
BACKGROUND AND OBJECTIVES: Growing demand for noninvasive skin tightening and reduction in fat results in an increasing pressure for devices with good clinical efficacy, consistency of results, and high patient comfort. The objective was to validate clinical efficacy and versatility of a novel device, which combines radiofrequency (RF) and ultrasound for treating skin laxity and fat deposits. METHODS: We treated 34 subjects with facial skin laxity and/or abundant body or arm fat deposits...
November 10, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28940691/long-term-follow-up-on-patients-treated-for-abdominal-fat-using-a-selective-contactless-radiofrequency-device
#5
Klaus Fritz, Carmen Salavastru
BACKGROUND AND OBJECTIVE: The aim of this study was to evaluate how abdominal circumferential reduction achieved after using a noninvasive radiofrequency device (BTL Vanquish, BTL Industries Inc., Boston, MA) evolves over a 4-year period. METHODS: This is a follow-up on patients who were treated in our practice for abdominal fat in an earlier published multicenter prospective study. Patients were recalled for biometric data collection 4 years (±60 days) after the last treatment...
September 22, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28938784/immunocastration-as-an-alternative-to-caponization-evaluation-of-its-effect-on-body-and-bone-development-and-on-meat-color-and-composition
#6
M A G Quaresma, I C Antunes, M F Ribeiro, S Prazeres, R J B Bessa, P Martins da Costa
Caponization is associated with some morbidity and mortality, which contributes to important economic losses. This practice is executed without any pain relief (neither anesthesia nor analgesia) and can be painful and without consideration of animal welfare. On the other hand, immunocastration accomplished by Improvac and Bovipriva in pigs and cattle represents a noninvasive procedure, and for that reason is regarded as an alternative with improved animal welfare. This study includes 4 experimental groups consisting of capons, slips, roosters, and birds submitted to the Improvac treatment...
October 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28902034/safety-and-efficacy-of-a-noninvasive-1-060-nm-diode-laser-for-fat-reduction-of-the-flanks
#7
Bruce Katz, Sean Doherty
BACKGROUND: Preliminary reports indicate a hyperthermic diode laser treatment could be a safe and effective method for noninvasive fat reduction using the 1,060-nm wavelength. This wavelength penetrates the skin to heat subcutaneous adipocytes causing cellular disruption, leaving extracellular lipids, and cellular debris to be evacuated naturally by the body. OBJECTIVE: To evaluate the safety and effectiveness of this modality for noninvasive fat reduction of the flanks...
September 4, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28901051/noninvasive-submental-fat-reduction-using-colder-cryolipolysis
#8
Hector Leal Silva, Esther Carmona Hernandez, Mariana Grijalva Vazquez, Sebastian Leal Delgado, Angel Perez Blanco
BACKGROUND: Cryolipolysis has shown to significantly reduce localized subcutaneous fat, including submental fat. Temperatures below -11°C have not been used to treat the submental region. OBJECTIVE: The purpose of this study was to evaluate safety and efficacy of Cryolipolysis for noninvasive reduction of submental fat using lower temperatures and reduced treatment time. METHODS: A small volume applicator was used to treat 15 subjects, using a noninvasive tissue cooling device (CoolSculpting System, ZELTIQ Aesthetics, Pleasanton, CA, USA) during 45 and 30 minutes at -12 and -15°C, respectively, to induce reduction of submental fat...
September 12, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28892558/the-ask1-inhibitor-selonsertib-in-patients-with-nonalcoholic-steatohepatitis-a-randomized-phase-2-trial
#9
Rohit Loomba, Eric Lawitz, Parvez S Mantry, Saumya Jayakumar, Stephen H Caldwell, Hays Arnold, Anna Mae Diehl, C Stephen Djedjos, Ling Han, Robert P Myers, G Mani Subramanian, John G McHutchison, Zachary D Goodman, Nezam H Afdhal, Michael R Charlton
Inhibition of apoptosis signal-regulating kinase 1 (ASK1), a serine/threonine kinase, leads to improvement in inflammation and fibrosis in animal models of nonalcoholic steatohepatitis (NASH). We evaluated the safety and efficacy of selonsertib, a selective inhibitor of ASK1, alone or in combination with simtuzumab, in patients with NASH and stage 2 or 3 liver fibrosis. In this multicenter phase 2 trial, 72 patients were randomized to receive 24 weeks of open-label treatment with either 6 or 18 mg of selonsertib orally once daily with or without once-weekly injections of 125 mg of simtuzumab, or simtuzumab alone...
September 11, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28628684/megasessions-efficacy-of-fewer-longer-treatment-sessions-for-fat-reduction-in-noninvasive-body-contouring-using-a-radiofrequency-based-device
#10
Diane Duncan
<p>While the field of noninvasive body contouring is booming, many patients still note a lesser result than they might achieve with a single session of liposuction or dermolipectomy. The duration of a noninvasive fat reduction treatment series can be daunting. Patients have questioned the worth of these procedures when the expected benefit is modest and the time they devote to the project is significant. An eight-patient mini-study was performed to see if two or three "megasessions" could be substituted for eight weekly sessions of bipolar radiofrequency based fat reduction treatments...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28526633/facial-skin-rejuvenation-by-autologous-dermal-microfat-transfer-in-photoaged-patients-clinical-evaluation-and-skin-surface-digital-profilometry-analysis
#11
Angelo Trivisonno, Alfredo Rossi, Massimo Monti, Donato Di Nunno, Christophe Desouches, Claudio Cannistra, Gabriele Toietta
Cumulative long-term exposure to solar ultraviolet radiation promotes premature skin aging characterized by wrinkle formation and reduced skin elasticity. In this study, we assessed whether microfat transfer could improve dermal and subcutaneous tissue thickness loss associated with photoaging. Twenty-one patients affected by facial photoaging (photodamage grade II-IV; age range 35-62 years; 19 females, 2 males; all of Caucasian origin) were treated using minimally invasive autologous dermal white fat transfer harvested with a recently designed microcannula...
August 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28210398/injection-adipolysis-mechanisms-agents-and-future-directions
#12
REVIEW
Shahraam Kamalpour, Keith Leblanc
Noninvasive procedures targeting the elimination of unwanted adipose tissues have recently been developed. injection adipolysis is the term for the injection of cytotoxic substances into these tissues, with the intent of cosmetic improvement by volume reduction. initial attempts in the field utilized intravenous preparations of sodium deoxycholate and soy-derived phosphatidylcholine, approved for the intravenous treatment of fat emboli and dyslipidemias in countries outside the United States. it was initially purported that the active ingredient in these injections was phosphatidylcholine...
December 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28123436/review-of-the-mechanisms-and-effects-of-noninvasive-body-contouring-devices-on-cellulite-and-subcutaneous-fat
#13
REVIEW
Zahra Alizadeh, Farzin Halabchi, Reza Mazaheri, Maryam Abolhasani, Mastaneh Tabesh
CONTEXT: Today, different kinds of non-invasive body contouring modalities, including cryolipolysis, radiofrequency (RF), low-level laser therapy (LLLT), and high-intensity focused ultrasound (HIFU) are available for reducing the volume of subcutaneous adipose tissue or cellulite. Each procedure has distinct mechanisms for stimulating apoptosis or necrosis adipose tissue. In addition to the mentioned techniques, some investigations are underway for analyzing the efficacy of other techniques such as whole body vibration (WBV) and extracorporeal shockwave therapy (ESWT)...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28099534/a-noninvasive-mechanical-treatment-to-reduce-the-visible-appearance-of-cellulite
#14
Paul J Roubal, Michael J Busuito, D Carl Freeman, Jeffrey D Placzek
Cellulite is a cosmetic condition of subcutaneous fat herniation through fibrous connective tissue that results in a dimpled appearance of the skin. Occurring in approximately 85% to 90% of all women worldwide, cellulite has been well studied. The result has been the development of a plethora of treatment protocols yielding little to no success. We describe a noninvasive mechanical treatment for women with cellulite, evaluating the safety and effectiveness of a technique that utilizes a unique patented device for the reduction of the visible appearance of cellulite...
December 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28095578/a-clinical-evaluation-of-a-next-generation-non-invasive-selective-radiofrequency-hands-free-body-shaping-device
#15
RANDOMIZED CONTROLLED TRIAL
Nicole Hayre, Melanie Palm, Peter Jenkin
OBJECTIVE: The aim of this study was to compare clinical outcomes of a noninvasive selective radiofrequency (RF) eld device (BTL Vanquish METM, BTL Industries Inc., Boston MA) with its predecessor (VanquishTM, BTL Industries Inc., Boston MA). The BTL Vanquish METM system has been thoroughly redesigned for more efficient, predictable and homogenous energy delivery to the targeted tissue. MATERIALS AND METHODS: In this multi-center study, 36 subjects with BMIs under 30 were randomly assigned to be treated in Group A (BTL Vanquish METM) or Group B (VanquishTM) in order to obtain a side by side comparison of the devices' ef cacies...
December 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28081309/simulation-of-cryolipolysis-as-a-novel-method-for-noninvasive-fat-layer-reduction
#16
Abbas Majdabadi, Mohammad Abazari
BACKGROUND/AIM: Regarding previous problems in conventional liposuction methods, the need for development of new fat removal operations was appreciated. In this study we are going to simulate one of the novel methods, cryolipolysis, aimed to tackle those drawbacks. MATERIALS AND METHODS: We think that simulation of clinical procedures contributes considerably in efficacious performance of the operations. To do this we have attempted to simulate temperature distribution in a sample fat of the human body...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28018773/noninvasive-submental-fat-compartment-treatment
#17
Ava T Shamban
BACKGROUND: KYBELLA, ATX-101, is an injectable form of sodium deoxycholic acid. It is currently the only Food and Drug Administration-approved injectable drug for the reduction of submental fat. OBJECTIVES: A literature review and discussion of the treatment of submental fat. RESULTS: KYBELLA is a well-tolerated alternative for the treatment of submental fat. CONCLUSIONS: KYBELLA is a safe and efficacious, first in class, injectable drug for the reduction of submental fat...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28009680/a-multicenter-controlled-study-to-evaluate-multiple-treatments-with-nonthermal-focused-ultrasound-for-noninvasive-fat-reduction
#18
RANDOMIZED CONTROLLED TRIAL
William P Coleman, William Coleman, Robert A Weiss, Jeffrey M Kenkel, Dean D Ad-El, Ruthie Amir
BACKGROUND: Demand for nonsurgical esthetic body procedures has led to the development of noninvasive techniques for reducing localized subcutaneous adipose tissue. OBJECTIVE: This study assessed multiple treatments with nonthermal focused ultrasound for noninvasive abdominal treatment of excess fat deposits. MATERIALS AND METHODS: Subjects were randomly assigned to Group 1 for a 4-week control phase before undergoing 3 abdominal fat reduction treatments, at 2-week intervals, or to Group 2 for immediate treatment...
January 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27895944/effects-of-cryolipolysis-on-abdominal-adiposity
#19
Patricia Froes Meyer, Rodrigo Marcel Valentim da Silva, Glenda Oliveira, Maely Azevedo da Silva Tavares, Melyssa Lima Medeiros, Camila Procopio Andrada, Luis Gonzaga de Araujo Neto
Cryolipolysis is a noninvasive technique of localized fat reduction. Controlled cold exposure is performed in the selective destruction of fat cells. The aim of this study was to investigate the effects of cryolipolysis on adipocytes elimination through histological and sonographic analyses. This study reports the case of a 46-year-old female patient, with complaint of localized abdominal fat and in the preoperative period of abdominoplasty. The patient was submitted to a single 60-minute application of cryolipolysis, temperature of -5°C, on the hypogastrium area, 5 cm below the umbilicus...
2016: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/27582882/association-of-noninvasive-quantitative-decline-in-liver-fat-content-on-mri-with-histologic-response-in-nonalcoholic-steatohepatitis
#20
Janki Patel, Ricki Bettencourt, Jeffrey Cui, Joanie Salotti, Jonathan Hooker, Archana Bhatt, Carolyn Hernandez, Phirum Nguyen, Hamed Aryafar, Mark Valasek, William Haufe, Catherine Hooker, Lisa Richards, Claude B Sirlin, Rohit Loomba
BACKGROUND: Magnetic resonance imaging-estimated proton-density-fat-fraction (MRI-PDFF) has been shown to be a noninvasive, accurate and reproducible imaging-based biomarker for assessing steatosis and treatment response in nonalcoholic steatohepatitis (NASH) clinical trials. However, there are no data on the magnitude of MRI-PDFF reduction corresponding to histologic response in the setting of a NASH clinical trial. The aim of this study was to quantitatively compare the magnitude of MRI-PDFF reduction between histologic responders versus histologic nonresponders in NASH patients...
September 2016: Therapeutic Advances in Gastroenterology
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