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Noninvasive fat reduction

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https://www.readbyqxmd.com/read/28628684/megasessions-efficacy-of-fewer-longer-treatment-sessions-for-fat-reduction-in-noninvasive-body-contouring-using-a-radiofrequency-based-device
#1
Diane Duncan
<p>While the field of noninvasive body contouring is booming, many patients still note a lesser result than they might achieve with a single session of liposuction or dermolipectomy. The duration of a noninvasive fat reduction treatment series can be daunting. Patients have questioned the worth of these procedures when the expected benefit is modest and the time they devote to the project is significant. An eight-patient mini-study was performed to see if two or three "megasessions" could be substituted for eight weekly sessions of bipolar radiofrequency based fat reduction treatments...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28526633/facial-skin-rejuvenation-by-autologous-dermal-microfat-transfer-in-photoaged-patients-clinical-evaluation-and-skin-surface-digital-profilometry-analysis
#2
Angelo Trivisonno, Alfredo Rossi, Massimo Monti, Donato Di Nunno, Christophe Desouches, Claudio Cannistra, Gabriele Toietta
Cumulative long-term exposure to solar ultraviolet radiation promotes premature skin aging characterized by wrinkle formation and reduced skin elasticity. In this study, we assessed whether microfat transfer could improve dermal and subcutaneous tissue thickness loss associated with photoaging. Twenty-one patients affected by facial photoaging (photodamage grade II-IV; age range 35-62 years; 19 females, 2 males; all of Caucasian origin) were treated using minimally invasive autologous dermal white fat transfer harvested with a recently designed microcannula...
April 22, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28210398/injection-adipolysis-mechanisms-agents-and-future-directions
#3
REVIEW
Shahraam Kamalpour, Keith Leblanc
Noninvasive procedures targeting the elimination of unwanted adipose tissues have recently been developed. injection adipolysis is the term for the injection of cytotoxic substances into these tissues, with the intent of cosmetic improvement by volume reduction. initial attempts in the field utilized intravenous preparations of sodium deoxycholate and soy-derived phosphatidylcholine, approved for the intravenous treatment of fat emboli and dyslipidemias in countries outside the United States. it was initially purported that the active ingredient in these injections was phosphatidylcholine...
December 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28123436/review-of-the-mechanisms-and-effects-of-noninvasive-body-contouring-devices-on-cellulite-and-subcutaneous-fat
#4
REVIEW
Zahra Alizadeh, Farzin Halabchi, Reza Mazaheri, Maryam Abolhasani, Mastaneh Tabesh
CONTEXT: Today, different kinds of non-invasive body contouring modalities, including cryolipolysis, radiofrequency (RF), low-level laser therapy (LLLT), and high-intensity focused ultrasound (HIFU) are available for reducing the volume of subcutaneous adipose tissue or cellulite. Each procedure has distinct mechanisms for stimulating apoptosis or necrosis adipose tissue. In addition to the mentioned techniques, some investigations are underway for analyzing the efficacy of other techniques such as whole body vibration (WBV) and extracorporeal shockwave therapy (ESWT)...
October 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28099534/a-noninvasive-mechanical-treatment-to-reduce-the-visible-appearance-of-cellulite
#5
Paul J Roubal, Michael J Busuito, D Carl Freeman, Jeffrey D Placzek
Cellulite is a cosmetic condition of subcutaneous fat herniation through fibrous connective tissue that results in a dimpled appearance of the skin. Occurring in approximately 85% to 90% of all women worldwide, cellulite has been well studied. The result has been the development of a plethora of treatment protocols yielding little to no success. We describe a noninvasive mechanical treatment for women with cellulite, evaluating the safety and effectiveness of a technique that utilizes a unique patented device for the reduction of the visible appearance of cellulite...
December 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28095578/a-clinical-evaluation-of-a-next-generation-non-invasive-selective-radiofrequency-hands-free-body-shaping-device
#6
RANDOMIZED CONTROLLED TRIAL
Nicole Hayre, Melanie Palm, Peter Jenkin
OBJECTIVE: The aim of this study was to compare clinical outcomes of a noninvasive selective radiofrequency (RF) eld device (BTL Vanquish METM, BTL Industries Inc., Boston MA) with its predecessor (VanquishTM, BTL Industries Inc., Boston MA). The BTL Vanquish METM system has been thoroughly redesigned for more efficient, predictable and homogenous energy delivery to the targeted tissue. MATERIALS AND METHODS: In this multi-center study, 36 subjects with BMIs under 30 were randomly assigned to be treated in Group A (BTL Vanquish METM) or Group B (VanquishTM) in order to obtain a side by side comparison of the devices' ef cacies...
December 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28081309/simulation-of-cryolipolysis-as-a-novel-method-for-noninvasive-fat-layer-reduction
#7
Abbas Majdabadi, Mohammad Abazari
BACKGROUND/AIM: Regarding previous problems in conventional liposuction methods, the need for development of new fat removal operations was appreciated. In this study we are going to simulate one of the novel methods, cryolipolysis, aimed to tackle those drawbacks. MATERIALS AND METHODS: We think that simulation of clinical procedures contributes considerably in efficacious performance of the operations. To do this we have attempted to simulate temperature distribution in a sample fat of the human body...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28018773/noninvasive-submental-fat-compartment-treatment
#8
Ava T Shamban
BACKGROUND: KYBELLA, ATX-101, is an injectable form of sodium deoxycholic acid. It is currently the only Food and Drug Administration-approved injectable drug for the reduction of submental fat. OBJECTIVES: A literature review and discussion of the treatment of submental fat. RESULTS: KYBELLA is a well-tolerated alternative for the treatment of submental fat. CONCLUSIONS: KYBELLA is a safe and efficacious, first in class, injectable drug for the reduction of submental fat...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28009680/a-multicenter-controlled-study-to-evaluate-multiple-treatments-with-nonthermal-focused-ultrasound-for-noninvasive-fat-reduction
#9
RANDOMIZED CONTROLLED TRIAL
William P Coleman, William Coleman, Robert A Weiss, Jeffrey M Kenkel, Dean D Ad-El, Ruthie Amir
BACKGROUND: Demand for nonsurgical esthetic body procedures has led to the development of noninvasive techniques for reducing localized subcutaneous adipose tissue. OBJECTIVE: This study assessed multiple treatments with nonthermal focused ultrasound for noninvasive abdominal treatment of excess fat deposits. MATERIALS AND METHODS: Subjects were randomly assigned to Group 1 for a 4-week control phase before undergoing 3 abdominal fat reduction treatments, at 2-week intervals, or to Group 2 for immediate treatment...
January 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27895944/effects-of-cryolipolysis-on-abdominal-adiposity
#10
Patricia Froes Meyer, Rodrigo Marcel Valentim da Silva, Glenda Oliveira, Maely Azevedo da Silva Tavares, Melyssa Lima Medeiros, Camila Procopio Andrada, Luis Gonzaga de Araujo Neto
Cryolipolysis is a noninvasive technique of localized fat reduction. Controlled cold exposure is performed in the selective destruction of fat cells. The aim of this study was to investigate the effects of cryolipolysis on adipocytes elimination through histological and sonographic analyses. This study reports the case of a 46-year-old female patient, with complaint of localized abdominal fat and in the preoperative period of abdominoplasty. The patient was submitted to a single 60-minute application of cryolipolysis, temperature of -5°C, on the hypogastrium area, 5 cm below the umbilicus...
2016: Case Reports in Dermatological Medicine
https://www.readbyqxmd.com/read/27582882/association-of-noninvasive-quantitative-decline-in-liver-fat-content-on-mri-with-histologic-response-in-nonalcoholic-steatohepatitis
#11
Janki Patel, Ricki Bettencourt, Jeffrey Cui, Joanie Salotti, Jonathan Hooker, Archana Bhatt, Carolyn Hernandez, Phirum Nguyen, Hamed Aryafar, Mark Valasek, William Haufe, Catherine Hooker, Lisa Richards, Claude B Sirlin, Rohit Loomba
BACKGROUND: Magnetic resonance imaging-estimated proton-density-fat-fraction (MRI-PDFF) has been shown to be a noninvasive, accurate and reproducible imaging-based biomarker for assessing steatosis and treatment response in nonalcoholic steatohepatitis (NASH) clinical trials. However, there are no data on the magnitude of MRI-PDFF reduction corresponding to histologic response in the setting of a NASH clinical trial. The aim of this study was to quantitatively compare the magnitude of MRI-PDFF reduction between histologic responders versus histologic nonresponders in NASH patients...
September 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/27440551/non-invasive-tumescent-cryolipolysis-using-a-new-4d-handpiece-a-comparative-study-with-a-porcine-model
#12
COMPARATIVE STUDY
S Y Jeong, T R Kwon, J Seok, K Y Park, B J Kim
BACKGROUND/PURPOSE: The growing demand for a youthful appearance, including a favorable body shape, has motivated recent developments in noninvasive body contouring techniques. Our aim was to investigate the efficacy and safety of a new version of a 4D handpiece-mounted cooling device for cryolipolysis with or without tumescent injections. METHODS: We conducted a side-by-side comparative study using two female porcine models. Two areas of each pig's left abdomen were treated using a conventional device and the new cooling device, and two areas of the right abdomen were also treated using the conventional and new cooling device, but both were combined with tumescent-solution injections...
February 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/27402002/evaluation-of-safety-and-efficacy-of-noninvasive-radiofrequency-technology-for-submental-rejuvenation
#13
Ji-Hye Park, Jung-In Kim, Hee Jin Park, Won-Serk Kim
Recently, a number of modalities have been used for noninvasive fat reduction. Radiofrequency (RF) technology is a promising tool for noninvasive body and face contouring. The aim of this study is to evaluate the efficacy and safety of novel noninvasive RF technology for the reduction of submental fat with 6 months of follow-up. Twenty-one subjects with submental fat accumulation were treated twice at 1-month intervals with monopolar RF, which could also be used to monitor real-time temperature. The submental fat thickness and the circumference were evaluated with ultrasonography and a tape measure, respectively, at baseline followed by 1 and 6 months after the last treatment (0, 2, and 7 months)...
November 2016: Lasers in Medical Science
https://www.readbyqxmd.com/read/27335309/long-term-efficacy-follow-up-on-two-cryolipolysis-case-studies-6-and-9-years-post-treatment
#14
Eric F Bernstein
Cryolipolysis is a noninvasive esthetic procedure that utilizes controlled cooling to reduce subcutaneous fat. Clinical studies have established its safety, efficacy, and tolerability for fat reduction in a variety of areas including the abdomen, flanks, thighs, submental area, arms, back, and chest. Because of obvious esthetic concerns, long-term unilateral studies leaving an untreated flank, thigh, or arm are not performed, but serve as ideal controls for weight gain or loss or re-distribution of fat for other reasons...
December 2016: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/27270537/skeletal-muscle-magnetic-resonance-imaging-of-the-lower-limbs-in-late-onset-lipid-storage-myopathy-with-electron-transfer-flavoprotein-dehydrogenase-gene-mutations
#15
Xin-Yi Liu, Ming Jin, Zhi-Qiang Wang, Dan-Ni Wang, Jun-Jie He, Min-Ting Lin, Hong-Xia Fu, Ning Wang
BACKGROUND: Lipid storage myopathy (LSM) is a genetically heterogeneous group with variable clinical phenotypes. Late-onset multiple acyl-coenzyme A dehydrogenation deficiency (MADD) is a rather common form of LSM in China. Diagnosis and clinical management of it remain challenging, especially without robust muscle biopsy result and genetic detection. As the noninvasion and convenience, muscle magnetic resonance imaging (MRI) is a helpful assistant, diagnostic tool for neuromuscular disorders...
June 20, 2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27248025/ways-of-noninvasive-facial-skin-tightening-and-fat-reduction
#16
Klaus Fritz, Carmen Salavastru
For skin tightening, ablative and nonablative lasers have been used with various parameters full or fractionated. Currently, other energy-based technologies have been developed such as radiofrequency (RF) from mono- to multipolar, microneedling RF, and high-intensity focused ultrasound. They heat up the tissue to a clinical endpoint. Temperatures above 42°C stimulate fibroblasts to produce more collagen and some technologies produce small coagulation points that allow to shrink and to tighten the tissue with less downtime or side effects...
June 2016: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/27110719/magnetic-resonance-imaging-of-changes-in-abdominal-compartments-in-obese-diabetics-during-a-low-calorie-weight-loss-program
#17
Lena J Vogt, Antje Steveling, Peter J Meffert, Marie-Luise Kromrey, Rebecca Kessler, Norbert Hosten, Janine Krüger, Simone Gärtner, Ali A Aghdassi, Julia Mayerle, Markus M Lerch, Jens-Peter Kühn
OBJECTIVES: To investigate changes in the fat content of abdominal compartments and muscle area during weight loss using confounder-adjusted chemical-shift-encoded magnetic resonance imaging (MRI) in overweight diabetics. METHODS: Twenty-nine obese diabetics (10/19 men/women, median age: 59.0 years, median body mass index (BMI): 34.0 kg/m2) prospectively joined a standardized 15-week weight-loss program (six weeks of formula diet exclusively, followed by reintroduction of regular food with gradually increasing energy content over nine weeks) over 15 weeks...
2016: PloS One
https://www.readbyqxmd.com/read/27050705/contactless-abdominal-fat-reduction-with-selective-rf%C3%A2-evaluated-by-magnetic-resonance-imaging-mri-case-study
#18
Jeanine Downie, Miroslav Kaspar
BACKGROUND: Noninvasive body shaping methods seem to be an ascending part of the aesthetics market. As a result, the pressure to develop reliable methods for the collection and presentation of their results has also increased. The most used techniques currently include ultrasound measurements of fat thickness in the treated area, caliper measurements, bioimpedance-based scale measurements or circumferential tape measurements. Although these are the most used techniques, almost all of them have some limitations in reproducibility and/or accuracy...
April 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/26985567/quantification-of-adipose-volume-reduction-with-a-prospective-study-analyzing-the-application-of-external-radiofrequency-energy-and-high-voltage-ultrashort-pulse-duration-electrical-fields
#19
Diane Irvine Duncan, Theresa H M Kim, Robbin Temaat
To date, there have been no objective measurements of subcutaneous volume loss following treatments with a noninvasive radiofrequency (RF)-based device. Twenty female patients were treated with a suction-coupled bipolar RF device using external RF energy combined with pulsed electromagnetic RF energy for subcutaneous fat reduction. Parameters followed included weight, Vectra measurements of abdominal circumference and torso volume, and high-definition ultrasound measurements of fat thickness. Measurements were taken before treatment and three times following treatment...
October 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/26962636/a-prospective-study-analyzing-the-application-of-radiofrequency-energy-and-high-voltage-ultrashort-pulse-duration-electrical-fields-on-the-quantitative-reduction-of-adipose-tissue
#20
Diane Irvine Duncan, Theresa H M Kim, Robbin Temaat
Noninvasive fat reduction is claimed by many device manufacturers, but proof of efficacy has been difficult to establish. This prospective study was designed to measure the reduction of fat thickness and actual volume reduction in 20 female patients treated with an external radiofrequency (RF) device. This device combines RF heat, suction coupled vacuum, and oscillating electrical pulses that induce adipocyte death over time. Patients underwent pre- and post-treatment and intercurrent measurements of weight, body mass index, ultrasonic transcutaneous fat thickness, and 2D and 3D Vectra photography with independent calculation of circumferential and volumetric change...
October 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
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