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Statistical modeling

Wei Wei Jia, Can Cui, Feng Ri Li
Based on 1534 knot data from 60 sample trees in a Korean pine plantation in Mengjiagang Forest Farm, Heilongjiang Province, China, mixed effect model of knot attributefactors (knot diameter, sound knot length, year of death of knot and knot angle) of Korean pine plantation was established using NLMIXED and GLIMMIX procedures of SAS software. The prediction accuracy of models was compared using evaluation statistics, such as Akaike information criterion (AIC), Bayesian information criterion (BIC), -2Log likelihood(-2LL), and likelihood ratio test (LRT)...
January 2018: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
Yao-Min Hung, Yu-Hsun Wang, Lichi Lin, Paul Yung Pou Wang, Jeng-Yuan Chiou, James Cheng-Chung Wei
OBJECTIVES: The aim of this study was to determine whether hydroxychloroquine (HCQ) usage is associated with incidental risk of coronary artery diseases (CAD) in patients with rheumatoid arthritis (RA). METHODS: The Longitudinal Health Insurance Database in Taiwan was used. The study cohort comprised of 1104 newly diagnosed RA patients between 2001-2010, and patients were followed until 31 December 2011. Patients with history of CAD before RA diagnosis were excluded...
April 24, 2018: International Journal of Clinical Practice
Nathan A Gillespie, Michael C Neale, Timothy C Bates, Lisa T Eyler, Christine Fennema-Notestine, Jasmin Vassileva, Michael J Lyons, Elizabeth C Prom-Wormley, Katie L McMahon, Paul M Thompson, Greig de Zubicaray, Ian B Hickie, John J McGrath, Lachlan T Strike, Miguel E Rentería, Matthew S Panizzon, Nicholas G Martin, Carol E Franz, William S Kremen, Margaret J Wright
BACKGROUND AND AIMS: Disentangling the putative impact of cannabis on brain morphology from other comorbid substance use is critical. After controlling for the effects of nicotine, alcohol and multi-substance use, this study aimed to determine whether frequent cannabis use is associated with significantly smaller subcortical grey matter volumes. DESIGN: Exploratory analyses using mixed linear models, one per region of interest (ROI), were performed whereby individual differences in volume (outcome) at seven subcortical ROIs were regressed onto cannabis and comorbid substance use (predictors)...
April 24, 2018: Addiction
Pablo R N Rocha, Flávio A de Freitas, Célio F F Angolini, Lucas-Smith F Vasconcelos, Alaíde L B da Silva, Emmanoel V Costa, Felipe M A da Silva, Marcos N Eberlin, Giovana A Bataglion, Patrícia K Soares, Hector H F Koolen
INTRODUCTION: Alkaloids-derived drugs are a billionaire world-market and several phytochemical investigations aim the identification of new sources and/or structures. Thus, improving the way of extracting and methods to quantify them are of utmost importance. OBJECTIVE: To quantify isoquinoline-derived alkaloids in Unonopsis duckei R.E. Fr. through a new validated high-performance liquid chromatography with tandem mass spectrometry (HPLC-MS/MS) method in combination with a statistical mixture design that aimed a proper direct extraction of these compounds from leaves...
April 24, 2018: Phytochemical Analysis: PCA
Bonnie Janzen, Laurie-Ann M Hellsten
PURPOSE: The contribution of unpaid family work quality to understanding social inequalities in women's mental health has been understudied and further limited by a scarcity of psychometrically sound instruments available to measure family work. Therefore, using a multi-item scale of family work quality with evidence of validity and reliability, the overall aim of the present study was to determine whether psychosocial qualities of unpaid family work contribute to educational inequities in women's mental health...
April 24, 2018: International Archives of Occupational and Environmental Health
S Kalafatakis, S Braekevelt, A Lymperatou, A Zarebska, C Hélix-Nielsen, L Lange, I V Skiadas, H N Gavala
Forward osmosis (FO) is a low energy-intensive process since the driving force for water transport is the osmotic pressure difference, Δπ, between the feed and draw solutions, separated by the FO membrane, where πdraw  > πfeed . The potential of FO in wastewater treatment and desalination have been extensively studied; however, regeneration of the draw solution (thereby generating clean water) requires application of an energy-intensive process step like reverse osmosis (RO). In this study, the potential of applying FO for direct water recirculation from diluted fermentation effluent to concentrated feedstock, without the need for an energy-intensive regeneration step (e...
April 24, 2018: Bioprocess and Biosystems Engineering
Ojekunle Z O, Jinadu O O E, Afolabi T A, Taiwo A M
This study aimed at assessing the environmental pollution and related hazards of industries at Agbara, Ogun State, Nigeria. A total of five sampling points were identified and selected at random. Environmental samples were collected on a weekly basis for duration of 10 weeks. Air pollutants measured were CO2 , CO, NO, NOx , VOCs, H2 S, SO2 , NH3 , PM2.5 andPM10 using standard procedure. Dust and plant samples were also collected and analyzed for heavy metals (Pb, Cr, Cd, Cu and Zn) using the Atomic Absorption Spectrophotometer (AAS)...
April 24, 2018: Scientific Reports
Lisbeth Fagerström, Marina Kinnunen, Jan Saarela
OBJECTIVE: To investigate whether the daily workload per nurse (Oulu Patient Classification (OPCq)/nurse) as measured by the RAFAELA system correlates with different types of patient safety incidents and with patient mortality, and to compare the results with regressions based on the standard patients/nurse measure. SETTING: We obtained data from 36 units from four Finnish hospitals. One was a tertiary acute care hospital, and the three others were secondary acute care hospitals...
April 24, 2018: BMJ Open
Steven J Fitzgerald, Terrence C Palmer, Matthew J Kraay
BACKGROUND: We developed an orthopedic hospitalist fellowship program for our total joint replacement program at a large urban academic medical center. The goal of the program was to improve patient outcomes, quality, and healthcare value through collaborative perioperative care and improved care coordination. This study evaluates the implementation and impact of our modified Hospitalist-Orthopaedic Team Co-management model on quality and performance metrics. METHODS: We reviewed our Quality Institute data using 3 databases for the 16 months before (PreOH) and 18 months after (PostOH) implementation...
March 21, 2018: Journal of Arthroplasty
D Herbert Opi, Olivia Swann, Alexander Macharia, Sophie Uyoga, Gavin Band, Carolyne M Ndila, Ewen Harrison, Mahamadou A Thera, Abdoulaye K Kone, Dapa A Diallo, Ogobara K Doumbo, Kirsten E Lyke, Christopher Plowe, Joann M Moulds, Mohammed Shebbe, Neema Mturi, Norbert Peshu, Kathryn Maitland, Ahmed Raza, Dominic P Kwiatkowski, Kirk A Rockett, Thomas Williams, J Alexandra Rowe
Malaria has been a major driving force in the evolution of the human genome. In sub-Saharan African populations, two neighbouring polymorphisms in the Complement Receptor One ( CR1 ) gene, named Sl2 and McCb , occur at high frequencies, consistent with selection by malaria. Previous studies have been inconclusive. Using a large case-control study of severe malaria in Kenyan children and statistical models adjusted for confounders, we estimate the relationship between Sl2 and McCb and malaria phenotypes, and find they have opposing associations...
April 25, 2018: ELife
Natasha Lelijveld, Jeanette Bailey, Amy Mayberry, Lani Trenouth, Dieynaba S N'Diaye, Hassan Haghparast-Bidgoli, Chloe Puett
BACKGROUND: Acute malnutrition is currently divided into severe (SAM) and moderate (MAM) based on level of wasting. SAM and MAM currently have separate treatment protocols and products, managed by separate international agencies. For SAM, the dose of treatment is allocated by the child's weight. A combined and simplified protocol for SAM and MAM, with a standardised dose of ready-to-use therapeutic food (RUTF), is being trialled for non-inferior recovery rates and may be more cost-effective than the current standard protocols for treating SAM and MAM...
April 24, 2018: Trials
Saman Maroufizadeh, Mostafa Hosseini, Abbas Rahimi Foroushani, Reza Omani-Samani, Payam Amini
BACKGROUND: Infertility can cause psychological distress and has a negative impact on quality of life (QoL). There have been no studies investigating the effect of depression on QoL in infertile couples at the dyadic level. This study aimed to investigate the effects of actors' and partners' depression on QoL in male-female dyads experiencing infertility using an innovative dyadic analysis approach, the Actor-Partner Interdependence Model (APIM). METHODS: We conducted this cross-sectional study on 180 infertile couples in Tehran, Iran, during August-September 2017...
April 24, 2018: Health and Quality of Life Outcomes
Sanjay Singh, Manish Gupta, Rajeev Kumar Seam, Harish Changotra
INTRODUCTION: Altered expression of many E2F family members have been reported in various human cancers. In this study, we investigated the role of non-synonymous single nucleotide polymorphisms (rs3213172 C/T, rs3213173 C/T, and rs3213176 G/A) of the gene E2F1 with cervical cancer. METHODS: A total of 181 samples including 90 cervical cancer patients and 91 healthy controls were genotyped. The genotype frequencies of these polymorphisms in collected samples were determined by either PCR-RFLP or PCR-ARFLP methods...
April 1, 2018: International Journal of Biological Markers
Y Zhang, J L Cheng, Y Li
Objective: To investigate the cerebral protective effect of shRNA down-regulated matrix metalloproteinase-9(MMP-9) on cerebral infarction rats. Methods: 32 SD rats were randomly divided into four groups (8 for each group): group A (sham operation group): the branches of external carotid artery were only separated and ligated and were not be inserted thread; group B (MCAO group): rat MCAO models were made referring to the conventional Longa method; group C (physiological saline group): rats were injected with 5 μl saline two weeks before MCAO models; group D (lentivirus intervention group): rats were injected with 5 μl lentivirus-mediated shRNA two weeks before MCAO models...
April 17, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
X X Liang, L D Liang, Y Y Zhang, J B Gao, Y G Zhang, X Liu, Q Chi
Objective: To quantitatively evaluate the quality of advanced modeled iterative reconstruction (ADMIRE) combined with 70 kVp and linear blending images in low dose dual energy (70 kVp/sn150 kVp) pulmonary angiography. Methods: A total of 74 cases with normal BMI underwent dual-source CT dual-energy pulmonary angiography with small amount of contrast medium (30 ml) from 2015 to 2017 from the First Affiliated Hospital of Zhengzhou University were randomly assigned to protocol Ⅰ(100 kVp/sn140 kVp) or protocol Ⅱ(70 kVp/sn150 kVp)...
April 3, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Sheng Chang, Bingfang Wu, Nana Yan, Jianjun Zhu, Qi Wen, Feng Xu
In this study, modified perpendicular drought index (MPDI) models based on the red-near infrared spectral space are established for the first time through the analysis of the spectral characteristics of GF-1 wide field view (WFV) data, with a high spatial resolution of 16 m and the highest frequency as high as once every 4 days. GF-1 data was from the Chinese-made, new-generation high-resolution GF-1 remote sensing satellites. Soil-type spatial data are introduced for simulating soil lines in different soil types for reducing errors of using same soil line...
April 23, 2018: Sensors
Xiangyan Ding, Feilong Li, Youxuan Zhao, Yongmei Xu, Ning Hu, Peng Cao, Mingxi Deng
This paper investigates the propagation of Rayleigh surface waves in structures with randomly distributed surface micro-cracks using numerical simulations. The results revealed a significant ultrasonic nonlinear effect caused by the surface micro-cracks, which is mainly represented by a second harmonic with even more distinct third/quadruple harmonics. Based on statistical analysis from the numerous results of random micro-crack models, it is clearly found that the acoustic nonlinear parameter increases linearly with micro-crack density, the proportion of surface cracks, the size of micro-crack zone, and the excitation frequency...
April 23, 2018: Materials
Ying Li, Shengke Yang, Qianli Jiang, Jie Fang, Wenke Wang, Yanhua Wang
The sludge from the water supply plant was investigated to remove fluoride ions from the water. To improve the adsorption ability, the original sludge sample was treated with fuel oxidation, pyrolysis, hydrochloric acid, and sulphuric acid methods, and hydrochloric acid treatment improved the adsorption capacity of the sludge on the fluoride in water significantly, with a maximum adsorption capacity to 140 mg/kg. The adsorption experimental data was the well fitted pseudo-first-order model and the Langmuir isotherms model...
April 23, 2018: International Journal of Environmental Research and Public Health
Xinyan Qin, Gongping Wu, Jin Lei, Fei Fan, Xuhui Ye
Power lines are extending to complex environments (e.g., lakes and forests), and the distribution of power lines in a tower is becoming complicated (e.g., multi-loop and multi-bundle). Additionally, power line inspection is becoming heavier and more difficult. Advanced LiDAR technology is increasingly being used to solve these difficulties. Based on precise cable inspection robot (CIR) LiDAR data and the distinctive position and orientation system (POS) data, we propose a novel methodology to detect inspection objects surrounding power lines...
April 22, 2018: Sensors
Kang Wu, Lijian Ding, Peng Zhu, Shuang Li, Shan He
The aim of this study was to determine the cumulative effect of fermentation parameters and enhance the production of docosahexaenoic acid (DHA) by Thraustochytrium sp. ATCC 26185 using response surface methodology (RSM). Among the eight variables screened for effects of fermentation parameters on DHA production by Plackett-Burman design (PBD), the initial pH, inoculum volume, and fermentation volume were found to be most significant. The Box-Behnken design was applied to derive a statistical model for optimizing these three fermentation parameters for DHA production...
April 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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