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Treatment of PFPS

Afshin Karimzadeh, Seyed Ahmad Raeissadat, Saleh Erfani Fam, Leyla Sedighipour, Arash Babaei-Ghazani
Plantar fasciitis is the most common cause of heel pain. Local injection modalities are among treatment options in patients with resistant pain. The aim of the present study was to evaluate the effect of local autologous whole blood compared with corticosteroid local injection in treatment of plantar fasciitis. In this randomized controlled multicenter study, 36 patients with chronic plantar fasciitis were recruited. Patients were allocated randomly into three treatment groups: local autologous blood, local corticosteroid injection, and control groups receiving no injection...
March 2017: Clinical Rheumatology
Pallavi Rawat, Charu Eapen, Kulathuran Pillai Seema
STUDY DESIGN: Randomized controlled trial. PURPOSE OF THE STUDY: To study the effect of adding rotator cuff (RC) muscles strengthening to joint mobilization and transcutaneous electrical nerve stimulation (TENS) in patients with adhesive capsulitis. METHODS: A prospective, parallel-group, randomised clinical trial was conducted on 42 patients. One group received TENS and joint mobilization and in the other group RC muscles strengthening was added...
November 21, 2016: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
Chengfu Yuan, Changdong Wang, Junjie Wang, Vikas Kumar, Firoz Anwar, Fangxiang Xiao, Gohar Mushtaq, Yufei Liu, Mohammad Amjad Kamal, Ding Yuan
Breast cancer is the second cause of cancer-related death among Women. Current therapies for breast cancer have adverse side-effects. Selenium (Se)-containing polysaccharides have multiple health benefits to humans. Pyracantha fortuneana (P. fortuneana) contains rich Se polysaccharides. We hypothesized that Se-containing polysaccharides from P. fortuneana possess anticancer activity on breast cancer via inhibiting growth and inducing apoptosis. This study aimed to assess the anticancer effect of Se-containing polysaccharides from P...
November 2016: Nutrition Research
Sadi Turkan, Mehmet Kalkan, Ozan Ekmekcioglu, Hacer Haltas, Coskun Sahin
Paratesticular fibrous pseudotumors (PFPs) are rare pathologies with quite wide and variable topographic-morphological features. It is difficult to distinguish PFPs from malignant masses. Treatment can be done by resection of the mass. We reported a young patient's findings about this rare pathology.
June 28, 2016: Rare Tumors
Gul Deniz Yilmaz Yelvar, Yasemin Çirak, Murat Dalkilinç, Yasemin Parlak Demir, Gul Baltaci, Mahmut Kömürcü, Gul Deniz Yilmaz Yelvar
BACKGROUND: Postural control allows performance of daily and sports activities. The previous studies show that postural sway inceases in orthopaedic injuries such as osteoarthritis and total knee arthroplasty. OBJECTIVE: To compare postural sway, risk of falling and function between individuals with and without patellofemoral pain syndrome (PFS). METHODS: This study included 22 subjects with patellofemoral pain syndrome, age-matched pain-free 22 females serving as a control group...
June 30, 2016: Journal of Back and Musculoskeletal Rehabilitation
Justin M Lantz, Alicia J Emerson-Kavchak, John J Mischke, Carol A Courtney
BACKGROUND AND PURPOSE: Patellofemoral pain syndrome (PFPS) is a common source of anterior knee pain. Controversy exists over the exact clinical findings which define PFPS, thus, diagnosis and management can be challenging for clinicians. There is paucity in the literature concerning joint mobilization as treatment for PFPS, particularly at the tibiofemoral joint, as standard management is currently focused on therapeutic exercise, orthotics, bracing and taping. Therefore, the purpose of this case report is to describe the effects of tibiofemoral joint mobilization in the successful treatment of an individual with chronic PFPS as it relates to pain, function and central processing of pain...
June 2016: International Journal of Sports Physical Therapy
Wolf Petersen, Andree Ellermann, Ingo Volker Rembitzki, Sven Scheffler, Mirco Herbort, Gert Peter Brüggemann, Raymond Best, Thore Zantop, Christian Liebau
BACKGROUND: It has been previously shown that exercise programs for patellofemoral pain syndrome (PFPS) can be supported by medially directed taping. Evidence supporting the use of patellar braces is limited because previous studies have been low quality. The aim of this study is to compare the outcomes of patients with PFPS after treatment with a medially directed patellar realignment brace and supervised exercise. METHODS: In a prospective randomized multicenter trial, 156 patients with PFPS were included and randomly assigned to 6 weeks of supervised physiotherapy in combination with the patellar realignment brace, or supervised physiotherapy alone...
July 2016: Archives of Orthopaedic and Trauma Surgery
Qianling Sun, Mengmeng Dong, Zhihui Wang, Changdong Wang, Deqiao Sheng, Zhihong Li, Debin Huang, Chengfu Yuan
Polysaccharides from medicinal plants exert antitumor activity in many cancers. Our previous study demonstrated that polysaccharides extracted from the selenium-enriched Pyracantha fortuneana (Se-PFPs) showed antiproliferative effect in breast cancer cell line. This study aimed to investigate the antitumor effect of Se-PFPs in ovarian cancer cells in vitro and in vivo. Se-PFPs could decrease cell viability, induce apoptosis, and inhibit migratory and invasive potentials in HEY and SKOV3 cells. These findings are supported by reduced expression of cyclin D1, Bcl-2 and MMP-9, enhanced cleavage of PARP and caspase-3, elevated activity of caspase-3 and caspase-9, and EMT (epithelial to mesenchymal transition) inhibition (elevated expression of E-cadherin and cytokeratin 19, and reduced expression of N-cadherin, vimentin, ZEB1 and ZEB2)...
May 10, 2016: Oncotarget
Toby O Smith, Benjamin T Drew, Toby H Meek, Allan B Clark
BACKGROUND: Patellofemoral pain syndrome (PFPS) is a painful musculoskeletal condition, which is characterised by knee pain located in the anterior aspect (front) and retropatellar region (behind) of the knee joint. Various non-operative interventions are suggested for the treatment of this condition. Knee orthoses (knee braces, sleeves, straps or bandages) are worn over the knee and are thought to help reduce knee pain. They can be used in isolation or in addition to other treatments such as exercise or non-steroidal anti-inflammatory medications...
December 8, 2015: Cochrane Database of Systematic Reviews
Mohammad Sadegh Ghasemi, Naser Dehghan
BACKGROUND: Patellofemoral pain syndrome (PFPS) is one of the most common disorders of the knee. Conservative approaches, as well as surgery, can decrease pain and the syndrome's progress effectively. OBJECTIVE: The aim of this study was to determine the effectiveness of neoprene palumbo orthosis (NPO) and Genu direxa stable orthosis (GDSO) on pain and the activities of daily living (ADL). METHODS: Thirty patients (males, ages 18 to 40) participated in this randomized blinded clinical trial...
October 2015: Electronic Physician
Brittany Barber, Jace Dergousoff, Margaret Nesbitt, Nicholas Mitchell, Jeffrey Harris, Daniel O'Connell, David Côté, Vincent Biron, Hadi Seikaly
BACKGROUND: Head and neck cancer (HNC) is a debilitating disease due in part to its effects on function, including speech, swallowing, and cosmesis. Previous studies regarding depression in HNC have focused on demographic predictors, incidence, and quality of life studies. There is, however, a paucity of studies that objectively address depressive symptoms in HNC patients and the resultant effects on post-treatment functional performance status. The aim of this study was to assess the relationship between preoperative depressive symptoms (PDS) and postoperative functional performance status (PFPS), in addition to other predictors of rehabilitation and survival...
September 18, 2015: Journal of Otolaryngology—Head & Neck Surgery
Wenjiao Wu, Dongguo Lin, Xintian Shen, Fangfang Li, Yuxin Fang, Kaiqun Li, Tianrong Xun, Guang Yang, Jie Yang, Shuwen Liu, Jian He
Influenza A viral (IAV) fusion peptides are known for their important role in viral-cell fusion process and membrane destabilization potential which are compatible with those of antimicrobial peptides. Thus, by replacing the negatively or neutrally charged residues of FPs with positively charged lysines, we synthesized several potent antimicrobial peptides derived from the fusogenic peptides (FPs) of hemagglutinin glycoproteins (HAs) of IAV. The biological screening identified that in addition to the potent antibacterial activities, these positively charged fusion peptides (pFPs) effectively inhibited the replication of influenza A viruses including oseltamivir-resistant strain...
2015: PloS One
Hsien-Te Peng, Chen-Yi Song
BACKGROUND: Closed kinetic chain and quadriceps strengthening, combined with flexibility exercises of the lower limb musculature, is a common treatment for patellofemoral pain syndrome (PFPS). The effectiveness has been well documented; however, very little is known about which factors predict treatment success. METHODS: A total of 43 female subjects with PFPS participated in an eight-week progressive leg press (LP) strengthening and stretching exercise program...
December 2015: Knee
Thiago R T Santos, Bárbara A Oliveira, Juliana M Ocarino, Kenneth G Holt, Sérgio T Fonseca
INTRODUCTION: Patellofemoral pain syndrome (PFPS) is characterized by anterior knee pain, which may limit the performance of functional activities. The influence of hip joint motion on the development of this syndrome has already been documented in the literature. In this regard, studies have investigated the effectiveness of hip muscle strengthening in patients with PFPS. OBJECTIVES: The aims of this systematic review were (1) to summarize the literature related to the effects of hip muscle strengthening on pain intensity, muscle strength, and function in individuals with PFPS and (2) to evaluate the methodological quality of the selected studies...
May 2015: Brazilian Journal of Physical Therapy
Chengfu Yuan, Zhihong Li, Muhua Yi, Xiaoxing Wang, Fan Peng, Fangxiang Xiao, Tao Chen, Changdong Wang, Gohar Mushtaq, Mohammad Amjad Kamal
We have previously reported that polysaccharides extracted from Pyracantha fortuneana (Maxim.) Li (P. fortuneana) lowered the oxidative stress and inhibited the inflammatory responses in mice. Our present study aims to determine the effects of Selenium enriched P. fortuneana polysaccharides (Se-PFPs) against carbon tetrachloride (CCl4)-induced liver injury in a mouse model. Our results displayed that CCl4 remarkably elevated the levels of alanine transferase (ALT), aspartate transaminase (AST), lactic dehydrogenase (LDH), cholesterol, triglycerides in serum...
2015: Medicinal Chemistry
Gül Deniz Yılmaz Yelvar, Gül Baltacı, Volga Bayrakcı Tunay, Ahmet Özgür Atay
OBJECTIVE: This study aimed to investigate the effect of postural stabilization exercises on pain, muscle strength and function in females with patellofemoral pain. METHODS: Forty-two volunteers with patellofemoral pain syndrome (PFPS) were included in this study. The subjects were randomly divided into two groups: Group 1 performed therapeutic knee and postural stabilization exercises (n=22); Group 2 performed therapeutic knee exercises only (n=20). All patients were evaluated for pain, hamstring flexibility, function, lower extremity strength and postural control before and after treatment and at the 12th week...
2015: Acta Orthopaedica et Traumatologica Turcica
Samantha A Campbell, Alison R Valier
Patellofemoral pain syndrome (PFPS) occurs in 25% of adolescents and adults and is the leading cause of knee pain in runners. Pain is commonly felt when ascending or descending stairs, deep squatting, kneeling, or running. There is no consensus on the etiology of this condition, but insufficient hip strength, malalignment of the lower extremity, hyperpronation of the foot, and patellar incongruence have been suggested. Common treatments of PFPS include strengthening of quadriceps and hip muscles, McConnell taping, electrical stimulation, and foot orthotics, but effectiveness of these treatments is inconclusive...
August 2016: Journal of Sport Rehabilitation
Mitchell Selhorst, William Rice, Todd Degenhart, Michael Jackowski, Melissa Tatman
BACKGROUND: Treatment of patellofemoral pain syndrome (PFPS) has been extensively studied in physical therapy literature. Patients with PFPS demonstrate quadriceps and hip musculature weakness, altered lower extremity (LE) kinematics, and decreased LE flexibility. Psychosocial factors have also been identified as an important factor in patients with PFPS. The authors hypothesize that an ordered approach addressing each of these impairments sequentially will result in greater improvement in PFPS symptoms...
April 2015: International Journal of Sports Physical Therapy
Alexandra Hott, Sigurd Liavaag, Niels Gunnar Juel, Jens Ivar Brox
BACKGROUND: Patellofemoral pain syndrome (PFPS), also known as Anterior Knee Pain, is a common cause of recurrent or chronic knee pain. The etiology is considered to be multifactorial but is not completely understood. At the current time the leading theory is that pathomechanics in the patellofemoral joint leads to PFPS. Traditionally, conservative treatment has focused on improving strength and timing in the quadriceps muscles. In recent years, evidence has been accumulating to support the importance of hip control and strengthening in PFPS...
February 25, 2015: BMC Musculoskeletal Disorders
Alexandra Hott, Sigurd Liavaag, Niels Gunnar Juel, Jens Ivar Brox
BACKGROUND: Patellofemoral pain syndrome (PFPS), also known as Anterior Knee Pain, is a common cause of recurrent or chronic knee pain. The etiology is considered to be multifactorial but is not completely understood. At the current time the leading theory is that pathomechanics in the patellofemoral joint leads to PFPS. Traditionally, conservative treatment has focused on improving strength and timing in the quadriceps muscles. In recent years, evidence has been accumulating to support the importance of hip control and strengthening in PFPS...
December 2015: BMC Musculoskeletal Disorders
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