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https://www.readbyqxmd.com/read/28102023/6-gingerol-rich-fraction-prevents-disruption-of-histomorphometry-and-marker-enzymes-of-testicular-function-in-carbendazim-treated-rats
#1
M Salihu, B O Ajayi, I A Adedara, E O Farombi
Previous investigations demonstrated that 6-gingerol-rich fraction (6-GRF) prevented testicular toxicity via inhibition of oxidative stress and endocrine disruption in CBZ-treated rats. The influence of 6-GRF on alterations in histomorphometry and marker enzymes of testicular function in CBZ-treated rats which hitherto has not been reported was investigated in this study. The animals were orally administered either CBZ (50 mg/kg) alone or in combination with 6-GRF (50, 100 and 200 mg/kg) for 14 consecutive days...
January 19, 2017: Andrologia
https://www.readbyqxmd.com/read/28090004/difference-in-dynamic-body-balance-between-forward-and-lateral-single-leg-hop-landing
#2
Yukiko Kawakami, Issei Ogasawara, Yasukazu Yonetani, Rikio Takao, Tatsuo Mae, Ken Nakata, Shuji Horibe
Since the loss of balance can result in falls or lower extremity injuries during sports or daily activities, quantitative evaluation of one's ability to maintain balance with changes in the direction of motion is crucial. The present study aimed to assess whether the trajectory length of the center of pressure (COP) and peak values of the ground reaction force (GRF) following a single-leg hop landing differ when hopping forward or laterally, and to ascertain disparities in balance characteristics due to differences in hop direction...
January 16, 2017: Kurume Medical Journal
https://www.readbyqxmd.com/read/28057348/lower-extremity-control-during-turns-initiated-with-and-without-hip-external-rotation
#3
Antonia M Zaferiou, Henryk Flashner, Rand R Wilcox, Jill L McNitt-Gray
The pirouette turn is often initiated in neutral and externally rotated hip positions by dancers. This provides an opportunity to investigate how dancers satisfy the same mechanical objectives at the whole-body level when using different leg kinematics. The purpose of this study was to compare lower extremity control strategies during the turn initiation phase of pirouettes performed with and without hip external rotation. Skilled dancers (n=5) performed pirouette turns with and without hip external rotation...
December 29, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28042857/estimation-of-ground-reaction-forces-and-moments-during-gait-using-only-inertial-motion-capture
#4
Angelos Karatsidis, Giovanni Bellusci, H Martin Schepers, Mark de Zee, Michael S Andersen, Peter H Veltink
Ground reaction forces and moments (GRF&M) are important measures used as input in biomechanical analysis to estimate joint kinetics, which often are used to infer information for many musculoskeletal diseases. Their assessment is conventionally achieved using laboratory-based equipment that cannot be applied in daily life monitoring. In this study, we propose a method to predict GRF&M during walking, using exclusively kinematic information from fully-ambulatory inertial motion capture (IMC). From the equations of motion, we derive the total external forces and moments...
December 31, 2016: Sensors
https://www.readbyqxmd.com/read/28028224/ape2-zf-grf-facilitates-3-5-resection-of-dna-damage-following-oxidative-stress
#5
Bret D Wallace, Zachary Berman, Geoffrey A Mueller, Yunfeng Lin, Timothy Chang, Sara N Andres, Jessica L Wojtaszek, Eugene F DeRose, C Denise Appel, Robert E London, Shan Yan, R Scott Williams
The Xenopus laevis APE2 (apurinic/apyrimidinic endonuclease 2) nuclease participates in 3'-5' nucleolytic resection of oxidative DNA damage and activation of the ATR-Chk1 DNA damage response (DDR) pathway via ill-defined mechanisms. Here we report that APE2 resection activity is regulated by DNA interactions in its Zf-GRF domain, a region sharing high homology with DDR proteins Topoisomerase 3α (TOP3α) and NEIL3 (Nei-like DNA glycosylase 3), as well as transcription and RNA regulatory proteins, such as TTF2 (transcription termination factor 2), TFIIS, and RPB9...
December 27, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27988162/synergetic-role-of-hypromellose-and-methacrylic-acid-copolymer-in-the-dissolution-improvement-of-amorphous-solid-dispersions
#6
Naoko Ohyagi, Keisuke Ueda, Kenjirou Higashi, Keiji Yamamoto, Kohsaku Kawakami, Kunikazu Moribe
Synergetic role of polymer blending on dissolution of amorphous solid dispersion was investigated. Dissolution rates of hypromellose (HPMC) and methacrylic acid copolymer (EUD) from the HPMC/EUD spray-dried sample (SPD) were improved compared to those of each single polymer SPD. Differential scanning calorimetry measurements revealed that the structural change in HPMC following heating was inhibited by co-spray-drying with EUD, suggesting an intermolecular interaction between the polymers. (13)C solid-state NMR spectroscopy detected the change induced in the hydroxyl group of HPMC by co-spray-drying with EUD...
December 14, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27957266/dynamic-thermo-mechanical-properties-of-various-flowable-resin-composites
#7
Stéphanie Jager, Rémy Balthazard, Marin Vincent, Abdessellam Dahoun, Eric Mortier
BACKGROUND: This study compared the storage modulus (E'), the loss modulus (E'') and the loss tangent (tan δ) of various flowable resin composites. MATERIAL AND METHODS: Grandio Flow (GRF), GrandioSo Heavy Flow (GHF), Filtek Supreme XTE (XTE) and Filtek Bulk Fill (BUL) flowable resins and Clinpro Sealant (CLI) ultra-flowable pit and fissure sealant resin were used. 25 samples were tested using a dynamical mechanical thermal analysis system in bending mode. Measurements were taken within a temperature range of 10 to 55°C...
December 2016: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/27942700/lower-extremity-biomechanical-demands-during-saut-de-chat-leaps
#8
Danielle N Jarvis, Kornelia Kulig
: In dance, high demands are placed on the lower extremity joints during jumping tasks. The purpose of this study was to compare biomechanical demands placed on the lower extremity joints during the takeoff and landing phases of saut de chat leaps. METHODS: Thirty healthy, experienced dancers with 20.8±4.9 yrs of dance training performed 5 saut de chat leaps. A three-dimensional motion analysis system and force plates were used to collect kinematic and kinetic data...
December 2016: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/27933074/comparative-genomic-analysis-of-the-grf-genes-in-chinese-pear-pyrus-bretschneideri-rehd-poplar-populous-grape-vitis-vinifera-arabidopsis-and-rice-oryza-sativa
#9
Yunpeng Cao, Yahui Han, Qing Jin, Yi Lin, Yongping Cai
Growth-regulating factors (GRFs) are plant-specific transcription factors that have important functions in regulating plant growth and development. Previous studies on GRF family members focused either on a single or a small set of genes. Here, a comparative genomic analysis of the GRF gene family was performed in poplar (a model tree species), Arabidopsis (a model plant for annual herbaceous dicots), grape (one model plant for perennial dicots), rice (a model plant for monocots) and Chinese pear (one of the economical fruit crops)...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27919485/the-required-coefficient-of-friction-for-evaluating-gait-alterations-in-people-with-multiple-sclerosis-during-gait
#10
Ilaria Pacifici, Manuela Galli, Ana Francisca Rozin Kleiner, Federica Corona, Giancarlo Coghe, Elisabetta Marongiu, Andrea Loi, Antonio Crisafulli, Eleonora Cocco, Maria Giovanna Marrosu, Massimiliano Pau
BACKGROUND: Required Coefficient of Friction (RCOF) is one of the most critical gait parameters associated to the occurrence of slipping in individuals affected by neurological disorders characterized by balance impairments. This study aims to calculate RCOF in people with Multiple Sclerosis (MS) on the basis of three-dimensional Gait Analysis (GA) data. METHODS: This study enrolls 22 people with MS (pwMS) who were characterized by an Expanded Disability Status Score in the range 1...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27914310/electrical-potentials-measured-on-the-surface-of-the-knee-reflect-the-changes-of-the-contact-force-in-the-knee-joint-produced-by-postural-sway
#11
Lin Zhu, Martin Garon, Éric Quenneville, Michael D Buschmann, Pierre Savard
Electroarthrography (EAG) is a novel technique for recording potentials on the knee surface that are generated by the compression of articular cartilage and that reflect both compression force and cartilage quality. The mechanical loading of the knee is achieved by transferring the subject's body weight from a bipedal stance to a unipedal stance. We hypothesized that EAG potentials change with postural sway. The study was performed on 20 normal subjects (10 male, 10 female; age 29±10.5 yrs.; mass 68.8±14...
October 18, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27912154/limb-dominance-foot-orientation-and-functional-asymmetry-during-walking-gait
#12
John D Polk, Rebecca M Stumpf, Karl S Rosengren
While healthy gait is often characterized as, or assumed to be symmetric, consistent asymmetries often exist. In this study, we test the hypotheses that asymmetries in lower limb function, as measured by ground reaction force characteristics, may be explained by differences in foot orientation or limb dominance. Peak ground reaction force (GRF) measurements, and impulses were obtained for thirty-six healthy subjects with simultaneous kinematic estimates of foot posture. Three gait tasks were performed: subjects walked i) with normal foot orientation, ii) with feet laterally rotated (outward), and iii) with feet aligned in the direction of movement (straight)...
November 18, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27863284/landing-from-different-heights-biomechanical-and-neuromuscular-strategies-in-trained-gymnasts-and-untrained-prepubescent-girls
#13
Α Christoforidou, D A Patikas, E Bassa, I Paraschos, S Lazaridis, C Christoforidis, C Kotzamanidis
The purpose of this study was to examine the biomechanics of the lower limb, during landing in female prepubertal gymnasts and prepubertal untrained girls, aged 9-12years. Ten healthy participants were included in each group and performed five landings from 20, 40, and 60cm. Kinematics, ground reaction forces (GRF) and electromyogram (EMG) from the lateral gastrocnemius, tibialis anterior, and vastus lateralis are presented. Gymnasts had higher vertical GRF and shorter braking phase during landing. Compared to untrained girls, gymnasts exhibited for all examined drop heights more knee flexion before and at ground contact, but less knee flexion at maximum knee flexion position...
November 9, 2016: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/27855449/-evaluation-of-the-german-research-foundation-s-grf-%C3%A2-clinical-trials-academy-for-junior-researchers%C3%A2-publications-and-funding-profiles
#14
Levka Dahmen, Frank Krummenauer
Background | The »Clinical Trials Academy for Junior Researchers« is a strategic funding instrument of the German Research Foundation (GRF). In clinical research, this program responds to an increasing lack of qualified clinician scientists. Application for participation in the workshop is based on a self-proposed academy project; participants can furthermore apply for a GRF grant to implement this academy project. This evaluation should quantify publication and third-party-funding profiles after participation in one of the previous GRF junior researchers workshops on clinical trials...
November 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27834579/patient-reported-efficacy-6-months-after-a-4-week-rehabilitation-intervention-in-individuals-with-chronic-ankle-instability
#15
Cynthia J Wright, Shelly W Linens
OBJECTIVE: To track the patient-reported efficacy of a 4-week intervention [wobble board (WB) or resistance tubing (RT)] in decreasing symptoms of Chronic Ankle Instability (CAI) at 6 months post-intervention (6PI) as compared to immediately post-intervention (IPI). DESIGN: Randomized controlled trial. PARTICIPANTS: Fourteen out of 21 participants (66.7%) responded to an electronic 6 month follow-up questionnaire (age: 19.6±0.9years, height: 1...
November 11, 2016: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/27820692/filler-content-surface-microhardness-and-rheological-properties-of-various-flowable-resin-composites
#16
S Jager, R Balthazard, A Dahoun, E Mortier
OBJECTIVES: The objectives of this study were to determine the filler content, the surface microhardness (at baseline and after immersion in water for 2 years), and the rheological properties of various flowable resin composites. METHODS: Three flowable resin composites (Grandioso Heavy Flow [GHF], Grandio Flow [GRF], Filtek Supreme XTE Flow [XTE]), one pit and fissure sealant resin composite (ClinPro [CLI]), and three experimental flowable resin composites with the same matrix and a variable filler content (EXPA, EXPB, EXPC) were tested...
November 2016: Operative Dentistry
https://www.readbyqxmd.com/read/27783247/nanostructured-zno-tio2-thin-film-oxide-as-anode-material-in-electrooxidation-of-organic-pollutants-application-to-the-removal-of-dye-amido-black-10b-from-water
#17
Sana El-Kacemi, Hicham Zazou, Nihal Oturan, Matthias Dietze, Mohamed Hamdani, Mohammed Es-Souni, Mehmet A Oturan
Electrochemical oxidative degradation of diazo dye Amido black 10B (AB10B) as model pollutant in water has been studied using nanostructured ZnO-TiO2 thin films deposited on graphite felt (GrF) substrate as anode. The influence of various operating parameters, namely the current intensity, the nature and concentration of catalyst, the nature of electrode materials (anode/cathode), and the adsorption of dye and ambient light were investigated. It was found that the oxidative degradation of AB10B followed pseudo first-order kinetics...
October 25, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27723362/changing-sagittal-plane-landing-styles-to-modulate-impact-and-tibiofemoral-force-magnitude-and-directions-relative-to-the-tibia
#18
Yohei Shimokochi, Jatin P Ambegaonkar, Eric G Meyer
CONTEXT: Ground reaction force (GRF) and tibiofemoral force magnitudes and directions have been shown to affect anterior cruciate ligament loading during landing. However, the kinematic and kinetic factors modifying these 2 forces during landing are unknown. OBJECTIVE: To clarify the intersegmental kinematic and kinetic links underlying the alteration of the GRF and tibiofemoral force vectors secondary to changes in the sagittal-plane body position during single-legged landing...
September 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/27722075/experimental-sensing-and-density-functional-theory-study-of-h2s-and-sof2-adsorption-on-au-modified-graphene
#19
Xiaoxing Zhang, Lei Yu, Xiaoqing Wu, Weihua Hu
A gas sensor is used to detect SF6 decomposed gases, which are related to insulation faults, to accurately assess the insulated status of electrical equipment. Graphene films (GrF) modified with Au nanoparticles are used as an adsorbent for the detection of H2S and SOF2, which are two characteristic products of SF6 decomposed gases. Sensing experiments are conducted at room temperature. Results demonstrate that Au-modified GrF yields opposite responses to the tested gases and is thus considered a promising material for developing H2S- and SOF2-selective sensors...
November 2015: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/27705058/estimates-of-running-ground-reaction-force-parameters-from-motion-analysis
#20
Gaspare Pavei, Elena Seminati, Jorge Ll Storniolo, Leonardo A Peyré-Tartaruga
We compared running mechanics parameters determined from ground reaction force (GRF) measurements with estimated forces obtained from double differentiation of kinematic (K) data from motion analysis in a broad spectrum of running speeds (1.94-5.56 m·s(-1)). Data were collected through a force-instrumented treadmill and compared at different sampling frequencies (900 and 300 Hz for GRF, 300 and 100 Hz for K). Vertical force peak, shape, and impulse were similar between K methods and GRF. Contact time, flight time and vertical stiffness (kvert) obtained from K showed the same trend as GRF with differences <5%, whereas leg stiffness (kleg) was not correctly computed by kinematics...
October 5, 2016: Journal of Applied Biomechanics
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