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https://www.readbyqxmd.com/read/28214755/identification-of-a-new-tert-leucinate-class-synthetic-cannabinoid-in-powder-and-spice-like-herbal-incenses-methyl-2-1-5-fluoropentyl-indole-3-carbonyl-amino-3-3-dimethyl-butanoate-5f-mdmb-pica
#1
Martijn D P Risseeuw, Peter Blanckaert, Vera Coopman, Stijn Van Quekelberghe, Serge Van Calenbergh, Jan Cordonnier
A brown powder and different product packages of "spice-like" herbal incenses were analyzed using a systematic identification approach based on liquid chromatography with diode array detector (HPLC-PDA) and gas chromatography mass spectrometry (GC-MS) with computer based library search against spectral libraries. However, the most predominant compound in the methanolic sample solutions could not be identified. In order to elucidate the chemical structure, a more extensive analysis of the material was initiated using liquid chromatography mass spectrometry (LC-MS), electrospray high resolution mass spectrometry (ESI-HRMS) and (1)H, (13)C and (19)F nuclear magnetic resonance spectroscopy (NMR), which allowed the identification and characterization of the major compound as methyl 2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethyl-butanoate (5F-MDMB-PICA)...
February 4, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28182720/effective-antibodies-immobilization-and-functionalized-nanoparticles-in-a-quartz-crystal-microbalance-based-immunosensor-for-the-detection-of-parathion
#2
Bartolomeo Della Ventura, Marco Iannaccone, Riccardo Funari, Massimo Pica Ciamarra, Carlo Altucci, Rosanna Capparelli, Sante Roperto, Raffaele Velotta
BACKGROUND: Biosensor-based detection provides a rapid and low-cost alternative to conventional analytical methods for revealing the presence of the contaminants in water as well as solid matrices. Although important to be detected, small analytes (few hundreds of Daltons) are an issue in biosensing since the signal they induce in the transducer, and specifically in a Quartz-Crystal Microbalance, is undetectable. A pesticide like parathion (M = 292 Da) is a typical example of contaminant for which a signal amplification procedure is desirable...
2017: PloS One
https://www.readbyqxmd.com/read/28172793/p530-azathioprine-in-the-maintenance-of-steroid-free-remission-in-inflammatory-bowel-disease-patients-efficacy-and-safety-in-five-years-of-follow-up
#3
C Cassieri, R Pica, E V Avallone, G Brandimarte, M Zippi, P Crispino, D De Nitto, G Lecca, C Corrado, P Vernia, P Paoluzi, E S Corazziari
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172671/p024-stratification-of-ulcerative-colitis-patients-according-to-distinctive-tissue-cytokine-profiles
#4
A Butera, D De Nitto, B Ciamberlano, A Giuliani, R Pica, A Pronio, M Boirivant
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28164344/qualitative-assessment-of-pica-experienced-by-frequent-blood-donors
#5
Melanie C Chansky, Melissa R King, Walter Bialkowski, Barbara J Bryant, Joseph E Kiss, Pam D'Andrea, Ritchard G Cable, Bryan R Spencer, Alan E Mast
BACKGROUND: Pica, the compulsive consumption of ice or other nonnutritious substances, is associated with iron deficiency, a common negative consequence of frequent blood donation. Because of this, blood donors, such as those participating in the Strategies to Reduce Iron Deficiency (STRIDE) study, are an ideal population to explore pica and iron deficiency. STUDY DESIGN AND METHODS: STRIDE was a 2-year intervention trial to assess the effectiveness of iron supplementation for mitigating iron deficiency in frequent blood donors...
February 5, 2017: Transfusion
https://www.readbyqxmd.com/read/28164004/atypical-presentation-of-multiple-foreign-body-ingestion
#6
Emrah Aydın, Sultan Bent, Burak Ayan
Foreign body ingestion is very common in childhood especially under 3 year of age. Pica syndrome is characterized by an appetite for substances that are largely non-nutritive. We present a 3-year old girl who presented to ER with symptoms and signs of intestinal obstruction.
January 2017: APSP Journal of Case Reports
https://www.readbyqxmd.com/read/28151701/corvids-outperform-pigeons-and-primates-in-learning-a-basic-concept
#7
Anthony A Wright, John F Magnotti, Jeffrey S Katz, Kevin Leonard, Alizée Vernouillet, Debbie M Kelly
Corvids (birds of the family Corvidae) display intelligent behavior previously ascribed only to primates, but such feats are not directly comparable across species. To make direct species comparisons, we used a same/different task in the laboratory to assess abstract-concept learning in black-billed magpies ( Pica hudsonia). Concept learning was tested with novel pictures after training. Concept learning improved with training-set size, and test accuracy eventually matched training accuracy-full concept learning-with a 128-picture set; this magpie performance was equivalent to that of Clark's nutcrackers (a species of corvid) and monkeys (rhesus, capuchin) and better than that of pigeons...
February 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28150053/healing-and-edible-clays-a-review-of-basic-concepts-benefits-and-risks
#8
Celso de Sousa Figueiredo Gomes
The use of clay by humans for medicinal and wellness purposes is most probably as old as mankind. Within minerals, due to its ubiquitous occurrence in nature and easy availability, clay was the first to be used and is still used worldwide. Healing clays have been traditionally used by man for therapeutic, nutritional and skin care purposes, but they could impart some important health and skin care risks. For instance, clay particles could adsorb and make available for elimination or excretion any potential toxic elements or toxins being ingested or produced, but they could adsorb and make available for incorporation, through ingestion or through dermal absorption, toxic elements, e...
February 1, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28144776/partial-wrap-clipping-of-the-entrance-of-the-pseudolumen-of-a-fusiform-aneurysm-in-the-posterior-inferior-cerebellar-artery-a-technical-note
#9
Yasushi Motoyama, Yoshiaki Takamura, Shuichi Yamada, Young-Su Park, Hiroyuki Nakase
BACKGROUND: Fusiform aneurysms in the posterior inferior cerebellar artery (PICA) are rare and challenging to treat. Surgical treatment options for a fusiform aneurysm in the PICA include trapping with/without bypass and wrap-clipping, when elimination of the pathological wall from the systemic circulation and prevention of perforator injury are important. In addition, lower cranial nerve impairment due to surgical manipulation should also be avoided. METHOD: A fusiform-shaped aneurysm was found in a proximal part of the PICA by magnetic resonance angiography undertaken for evaluation of repeated vertigo in a 36-year-old man...
January 31, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28139499/desmoplasia-influenced-recurrence-of-disease-and-mortality-in-stage-iii-colorectal-cancer-within-five-years-after-surgery-and-adjuvant-therapy
#10
Maddalena Zippi, Giorgio De Toma, Giovanni Minervini, Claudio Cassieri, Roberta Pica, Diodoro Colarusso, Simon Stock, Pietro Crispino
BACKGROUND/AIMS: In patients with colon cancer who undergo resection for potential cure, 40-60% have advanced locoregional disease (stage III). Those who are suitable for adjuvant treatment had a definite disease-free-survival benefit. The aim of the present study was to demonstrate whether the presence of desmoplasia influenced the mortality rate of stage III colorectal cancer (CRC) within 5 years from the surgery and adjuvant therapy. PATIENTS AND METHODS: Sixty-five patients with stage III CRC underwent resection and adjuvant therapy...
January 2017: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/28133987/ruptured-intracranial-vertebral-artery-dissecting-aneurysms-an-evaluation-of-prognostic-factors-of-treatment-outcome
#11
K Urasyanandana, P Withayasuk, D Songsaeng, T Aurboonyawat, E Chankaew, A Churojana
Objective Intracranial spontaneous vertebral artery dissecting aneurysms commonly occur in the third to fifth decades of life, and are mostly associated with hypertension. Patients present with intracranial haemorrhage or thromboembolic events. Patients who present with intracranial haemorrhage carry about a 70% risk of recurrent bleeding. Patients with a posterior-inferior cerebellar artery (PICA) or ipsilateral dominant vertebral artery involve selecting which parent vessel could not be sacrificed. Recent reconstructive techniques such as stent-assisted coiling embolisation and flow-diverting stents are effective treatments of choice...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28125595/the-language-of-geometry-fast-comprehension-of-geometrical-primitives-and-rules-in-human-adults-and-preschoolers
#12
Marie Amalric, Liping Wang, Pierre Pica, Santiago Figueira, Mariano Sigman, Stanislas Dehaene
During language processing, humans form complex embedded representations from sequential inputs. Here, we ask whether a "geometrical language" with recursive embedding also underlies the human ability to encode sequences of spatial locations. We introduce a novel paradigm in which subjects are exposed to a sequence of spatial locations on an octagon, and are asked to predict future locations. The sequences vary in complexity according to a well-defined language comprising elementary primitives and recursive rules...
January 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28122128/an-8-item-short-form-of-the-eating-disorder-examination-questionnaire-adapted-for-children-chede-q8
#13
Sören Kliem, Ricarda Schmidt, Mandy Vogel, Andreas Hiemisch, Wieland Kiess, Anja Hilbert
Eating disturbances are common in children placing a vulnerable group of them at risk for full-syndrome eating disorders and adverse health outcomes. To provide a valid self-report assessment of eating disorder psychopathology in children, a short form of the child version of the Eating Disorder Examination (ChEDE-Q) was psychometrically evaluated. Similar to the EDE-Q, the ChEDE-Q provides assessment of eating disorder psychopathology related to anorexia nervosa, bulimia nervosa, and binge-eating disorder; however, the ChEDE-Q does not assess symptoms of avoidant/restrictive food intake disorder, pica, or rumination disorder...
January 25, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28120904/escape-rate-and-diffusion-of-a-stochastically-driven-particle
#14
Antonio Piscitelli, Massimo Pica Ciamarra
The dynamical properties of a tracer repeatedly colliding with heat bath particles can be described within a Langevin framework provided that the tracer is more massive than the bath particles, and that the collisions are frequent. Here we consider the escape of a particle from a potential well, and the diffusion coefficient in a periodic potential, without making these assumptions. We have thus investigated the dynamical properties of a Stochastically Driven particle that moves under the influence of the confining potential in between successive collisions with the heat bath...
January 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28118952/the-only-case-of-mycotic-aneurysm-of-the-pica-clinical-radiological-remarks-and-review-of-literature
#15
Manolo Piccirilli, Emiliano Prizio, Delia Cannizzaro, Maria Pia Tropeano, Giulio Guidetti, Antonio Santoro
We present the first and only case, reported in literature, of a 67-years-old man with a mycotic aneurysm (MA) of the left posterior inferior cerebellar artery (PICA), caused by group B Streptococcus, that we surgically treated, performing neck aneurysm clipping, preserving patency of parent vessel. Moreover the peculiarity of this case is represented by the fact that the MA is originated from a tooth abscess, treated about two years before. To date, there have been only 10 cases of association between MA with either tooth pathologies or dental surgical procedures and our case is the only one originating from PICA...
January 21, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28095387/mri-of-cerebellar-infarction
#16
Laurens J L De Cocker, Karl-Olof Lövblad, Jeroen Hendrikse
BACKGROUND: MRI is the imaging modality of choice for diagnosing brain infarction. Because of few or atypical clinical symptoms and a relatively low sensitivity of CT scans, many cerebellar infarctions may be detected only with MRI. With adequate recognition of cerebellar infarction on MRI and prompt initiation or optimisation of preventive therapeutic measures, more dramatic strokes may be avoided in selected cases. SUMMARY: We first briefly review the clinical presentation of cerebellar infarctions, followed by a short refresher on cerebellar anatomy and pathophysiological mechanisms of cerebellar infarcts...
January 18, 2017: European Neurology
https://www.readbyqxmd.com/read/28066873/management-of-posterior-inferior-cerebellar-artery-aneurysms-what-factors-play-the-most-important-role-in-outcome
#17
Alena Sejkorová, Ondra Petr, Miriam Mulino, Jiří Cihlář, Aleš Hejčl, Claudius Thomé, Martin Sameš, Giuseppe Lanzino
BACKGROUND: Posterior inferior cerebellar artery (PICA) aneurysms are an uncommon, heterogeneous group of aneurysms with poorer clinical outcomes compared to other intracranial aneurysms. We performed a multicenter retrospective study to analyze the outcome in a large series of patients treated with modern microsurgical and endovascular techniques. METHODS: Records of 94 patients treated for PICA aneurysms between 2000 and 2015 at three large tertiary referral centers were retrospectively reviewed...
March 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28038815/circadian-variation-in-acute-myocardial-infarct-size-assessed-by-cardiovascular-magnetic-resonance-in-reperfused-stemi-patients
#18
Heerajnarain Bulluck, Jennifer Nicholas, Gabriele Crimi, Steven K White, Andrew J Ludman, Silvia Pica, Claudia Raineri, Hector A Cabrera-Fuentes, Derek Yellon, Jose Rodriguez-Palomares, David Garcia-Dorado, Derek J Hausenloy
OBJECTIVE: Clinical studies using serum cardiac biomarkers to investigate a circadian variation in acute myocardial infarct (MI) size in ST-segment elevation myocardial infarction (STEMI) patients reperfused by primary percutaneous coronary intervention (PPCI) have produced mixed results. We aimed to investigate this phenomenon using acute MI size measured by cardiovascular magnetic resonance (CMR). METHODS: Patient-level data was obtained from 4 randomized controlled trials investigating the MI-limiting effects of cardioprotective therapies in this pooled analysis...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28008208/ruptured-partially-thrombosed-anterior-inferior-cerebellar-artery-aneurysms-two-case-reports-and-review-of-literature
#19
Fumiaki Kanamori, Teppei Kawabata, Shinsuke Muraoka, Takao Kojima, Tadashi Watanabe, Norikazu Hatano, Yukio Seki
Aneurysms arising from the distal anterior inferior cerebellar artery (AICA) are very rare. When the parent artery is an AICA-posterior inferior cerebellar artery (PICA) variant, occlusion of the artery, even distal to the meatal loop, leads to a significant area of cerebellar infarction. We report two cases of ruptured partially thrombosed distal AICA aneurysms. In both cases, the parent artery was an AICA-PICA variant. The aneurysms were clipped in one case and trapped following occipital artery (OA)-AICA anastomosis in another case...
December 2016: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28003171/a-contralateral-transcondylar-fossa-approach-with-bilateral-v3-segment-exposure-for-repairing-complex-vertebral-artery-aneurysms-a-technical-case-report
#20
Nakao Ota, Rokuya Tanikawa, Masataka Miyama, Takanori Miyazaki, Yu Kinoshita, Hidetoshi Matsukawa, Fumihiro Sakakibara, Norihiro Saito, Shiro Miyata, Kosumo Noda, Toshiyuki Tsuboi, Hiroyasu Kamiyama, Sadahisa Tokuda, Kyousuke Kamada
BACKGROUND: and Importance: Microsurgical treatment for vertebral artery aneurysms can be approached through the lateral aspect of the brainstem and cerebellum. Contralateral approach may be selected in case of complex aneurysms with tortuous running, and the intracranial vertebral artery distal to the aneurysm locates in contralateral cerebello-pontine angle. When performing the aneurysm repair, exposing the V3 segment before craniotomy is advantageous. We describe the detailed surgical procedures about contralateral transcondylar fossa approach with bilateral V3 segment exposure for the repair of a complex vertebral artery aneurysm...
December 18, 2016: World Neurosurgery
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