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Haoyu Wen, Massimo Pica Ciamarra, Siew Ann Cheong
There is growing interest in the use of critical slowing down and critical fluctuations as early warning signals for critical transitions in different complex systems. However, while some studies found them effective, others found the opposite. In this paper, we investigated why this might be so, by testing three commonly used indicators: lag-1 autocorrelation, variance, and low-frequency power spectrum at anticipating critical transitions in the very-high-frequency time series data of the Australian Dollar-Japanese Yen and Swiss Franc-Japanese Yen exchange rates...
2018: PloS One
Eli T Newcomb, Louis P Hagopian
Children with autism spectrum disorder (ASD) and intellectual disabilities (ID) present with problem behaviour at rates disproportionately higher than their typically-developing peers. Problem behaviour, such as self-injury, aggression, pica, disruption, and elopement result in a diminished quality-of-life for the individual and family. Applied behaviour analysis has a well-established research base, detailing a number of assessment and treatment methods designed to address behaviour problems in children with ASD and ID...
March 14, 2018: International Review of Psychiatry
Liping Fu, Linwen Liu, Jinming Zhang, Baixuan Xu, Yong Fan, Jiahe Tian
The aim of this study was to identify the brain networks from early-phase11 C-PIB (perfusion PIB, pPIB) data and to compare the brain networks of patients with differentiating Alzheimer's disease (AD) with cognitively normal subjects (CN) and of mild cognitively impaired patients (MCI) with CN. Forty participants (14 CN, 12 MCI, and 14 AD) underwent11 C-PIB and18 F-FDG PET/CT scans. Parallel independent component analysis (pICA) was used to identify correlated brain networks from the11 C-pPIB and18 F-FDG data, and a two-sample t -test was used to evaluate group differences in the corrected brain networks between AD and CN, and between MCI and CN...
2018: Contrast Media & Molecular Imaging
Antonio Pierro, Gennaro Pica, Anna Maria Giannini, E Tory Higgins, Arie W Kruglanski
The present research addresses the question of whether regulatory-mode orientations affect self-forgiveness. We expected that people with a strong locomotion orientation would be more inclined to self-forgiveness because of their tendencies toward movement and change, which focus them on the future, whereas people with a strong assessment orientation would refrain from self-forgiveness due to their evaluative tendencies which focus them on the past. These hypotheses were supported by the results in four studies that tested the relation between regulatory modes and self-forgiveness by measuring (Studies 1, 3 and 4) and manipulating (Study 2) regulatory-mode-orientations...
2018: PloS One
Myoung Soo Kim
OBJECTIVE: Sometimes a vertebral artery (VA) enters the spinal canal via the C1-2 intervertebral space, a variation regarded as a C2 segmental-type VA. This paper describes the anatomy of the C2 segmental-type VA and reviews its clinical importance. METHODS: Between March 2014 and November 2015, 3386 patients underwent computed tomographic angiography. I identified C2 segmental-type VAs, associated vascular variation, the origin of ipsilateral posterior inferior cerebellar arteries (PICAs), and the clinical symptoms associated with C2 segmental-type VAs...
March 2018: Journal of Korean Neurosurgical Society
Amy Talbot, Carys Lippiatt, Avanish Tantry
A 2-year-old boy with a history of pica was admitted with vomiting and treated overnight for viral tonsillitis. A week later, he presented with a prolonged afebrile seizure and required intubation and ventilation. Antibiotics and acyclovir were started. Despite extensive investigations including MRI head, no cause was identified. Four days later, he deteriorated with signs of raised intracranial pressure. On day 5, blood lead concentration in the sample collected at admission was reported as grossly elevated, consistent with a diagnosis of severe lead poisoning from ingesting lead-containing paint at the family home...
March 9, 2018: BMJ Case Reports
Muhammad Taimur Malik, Edgar J Kenton Iii, Dana Vanino, Shamsher S Dalal, Ramin Zand
Posterior inferior cerebellar artery (PICA) aneurysms are rare. The most common complication of intracranial aneurysms is rupture causing subarachnoid hemorrhage. Ischemic infarct, although more common in giant thrombosed aneurysms, is a very rare manifestation of small intracranial aneurysms. Here we describe a patient who presented with lateral medullary acute infarction associated with an ipsilateral, small (4 × 3.5 mm), unruptured and non-thrombosed PICA aneurysm.
September 2017: Case Reports in Neurology
Yuan Zhang, Shiqing Sun, Qi Xu, Weihua Feng, Haisong Chen
RATIONALE AND OBJECTIVES: The posterior inferior cerebellar artery aneurysm (PICAA), especially distal PICAA, is easily missed by a doctor, leading to misdiagnosis and treatment delays. The objective of this article is to report the computed tomography angiography (CTA) presentations of 30 cases of PICAA proved by digital subtraction angiography (DSA) or surgical operation, and analyze the causes of misdiagnosis of PICAA by CTA. MATERIALS AND METHODS: Thirty cases of patients with PICAA that were proved by DSA or surgical operation were included in this study, all of whom underwent CTA before surgical procedure...
March 1, 2018: Academic Radiology
Riccardo Via, Fabian Hennings, Giovanni Fattori, Aurora Fassi, Alessia Pica, Antony Lomax, Damien Charles Weber, Guido Baroni, Jan Hrbacek
PURPOSE: Over the last four decades, Ocular Proton Therapy has been successfully used to treat patients affected by intraocular lesions. For this, treatment geometry verification is routinely performed using radiographic images to align a configuration of fiducial radiopaque markers implanted on the sclera outer surface. This paper describes the clinical application of an alternative approach based on optical eye tracking for three-dimensional non-invasive and automatic eye localization...
March 1, 2018: Medical Physics
Khursheed Ahmad Ansari, Girish Menon, Suresh Nair, Mathew Abraham
Aneurysms arising from anterior inferior cerebellar artery-posterior inferior cerebellar artery (AICA-PICA) variant are extremely rare. They usually present with subarachnoid hemorrhage. This is probably the second case report of a large thrombosed AICA-PICA variant aneurysm presenting as a cerebellopontine angle mass lesion with cranial nerve palsy, managed successfully by surgical clipping.
January 2018: Asian Journal of Neurosurgery
Muhammad Yaman Adi, William Adams
Anomalous origin of the right vertebral artery from the right common carotid artery (VA-CCA) with an aberrant right subclavian artery (ARSCA) is an uncommon anatomical variant. We present a series of images from a case in which this was identified on angiography for the management of a right posterior inferior cerebellar artery (PICA) aneurysm. This combination has not been previously described in the literature. The embryological mechanism of this variation, the incidence of these individual findings and the clinical implications will be discussed...
February 28, 2018: British Journal of Neurosurgery
Beat Bojaxhiu, Frank Ahlhelm, Marc Walser, Lorenzo Placidi, Ulrike Kliebsch, Lorentzos Mikroutsikos, Petra Morach, Alessandra Bolsi, Tony Lomax, Alessia Pica, Damien C Weber
PURPOSE: To assess the rate of radiation necrosis (RN) and white matter lesions (WMLs) in pediatric patients with primary brain tumors treated with pencil beam scanning (PBS) proton therapy (PT) with or without concomitant chemotherapy at the PSI. METHODS AND MATERIALS: Between 1999 and 2015, 171 pediatric patients (age <18 years) were treated with PT. Median age at diagnosis was 3.3 years (range, 0.3-17.0 years), and the median delivered dose was 54 Gy (relative biological effectiveness) (range, 40...
March 15, 2018: International Journal of Radiation Oncology, Biology, Physics
Andrea Pica, Giuseppe Graziano
Simple calculations, grounded on the geometric approach to hydrophobic interaction, confirm the occurrence of a minimum in the Gibbs free energy change associated with the formation of several hard sphere clusters in water-methanol solutions with a methanol molar fraction of around 0.3, at room temperature and atmospheric pressure. This finding is in line with the computer simulation results of Mochizuki and Koga [Phys. Chem. Chem. Phys., 2016, 18, 16188]. However, it is underscored that these results cannot be the basis for a rationalization of the cononsolvency phenomenon of the polymers in water-methanol solutions...
February 27, 2018: Physical Chemistry Chemical Physics: PCCP
Eric C Mason, Patricia A Hudgins, Gustavo Pradilla, Nelson M Oyesiku, C Arturo Solares
BACKGROUND: Endoscopic endonasal surgery of the skull base requires expert knowledge of the anatomy and a systematic approach. The vidian canal is regarded as a reliable landmark to localize the petrous internal carotid artery (pICA) near the second genu, which can be used for orientation in deep skull base approaches. There is controversy about the relationship between the vidian canal and the pICA. OBJECTIVE: To further establish the vertical relationship between the vidian canal and the pICA to aid in surgical approaches to the skull base...
February 21, 2018: Operative Neurosurgery (Hagerstown, Md.)
Alessandro Mandurino-Mirizzi, Gabriele Crimi, Claudia Raineri, Silvia Pica, Marta Ruffinazzi, Umberto Gianni, Alessandra Repetto, Marco Ferlini, Barbara Marinoni, Sergio Leonardi, Stefano De Servi, Luigi Oltrona Visconti, Gaetano M De Ferrari, Maurizio Ferrario
AIMS: Elevated serum uric acid (eSUA) was associated with unfavorable outcome in patients with ST-segment elevation myocardial infarction (STEMI). However, the effect of eSUA on myocardial reperfusion injury and infarct size has been poorly investigated. Our aim was to correlate eSUA with infarct size, infarct size shrinkage, myocardial reperfusion grade and long-term mortality in STEMI patients undergoing primary percutaneous coronary intervention. METHODS: We performed a post-hoc patients-level analysis of two randomized controlled trials, testing strategies for myocardial ischemia/reperfusion injury protection...
February 20, 2018: Journal of Cardiovascular Medicine
F Giacco, L de Arcangelis, M Pica Ciamarra, E Lippiello
According to the acoustic fluidization hypothesis, elastic waves at a characteristic frequency form inside seismic faults even in the absence of an external perturbation. These waves are able to generate a normal stress which contrasts the confining pressure and promotes failure. Here, we study the mechanisms responsible for this wave activation via numerical simulations of a granular fault model. We observe the particles belonging to the percolating backbone, which sustains the stress, to perform synchronized oscillations over ellipticlike trajectories in the fault plane...
January 2018: Physical Review. E
Andrea Sisti, Cesare Brandi, Luca Grimaldi, Edoardo Pica Alfieri, Roberto Cuomo, Irene Zerini, Giuseppe Nisi
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer with a neuroendocrine phenotype. Here, the authors reported a case of MCC, presented as a rapidly growing, asymptomatic, erythematous nodule measuring 3.8 cm × 2.8 cm in diameter on the right cheek of an 85-year-old Caucasian woman. After resection of the nodule, the defect was repaired with cutaneous graft taken from the supraclavicular area and healed uneventfully. Histopathologic examination confirmed the diagnosis of MCC.
February 6, 2018: Journal of Craniofacial Surgery
Makoto Katsuno, Akira Matsuno
Background: Although vertebral artery (VA) dissecting aneurysms are treated by direct or endovascular surgery, some disadvantages are associated with each surgery. Therefore, the type of surgery should be selected based on the condition of the aneurysm. We performed aneurysm trapping by endovascular surgery via the contralateral VA after proximal direct ligation with bypass to prevent complications as well as achieve complete treatment. Case Description: We attempted to insert a distal clip to achieve complete trapping of the ruptured VA dissecting aneurysm after proximal ligation with occipital artery-posterior inferior cerebellar artery (PICA) anastomosis; however, the operative field was limited by the existence of lower cranial nerves, brain swelling, and tortuosity of VA...
2018: Surgical Neurology International
Peng Gao, Yabing Wang, Yan Ma, Qi Yang, Haiqing Song, Yanfei Chen, Liqun Jiao, Adnan I Qureshi
OBJECTIVE: The optimal treatment of chronic symptomatic total occlusion of the intracranial vertebral artery (ICVA) remains undefined. We report a single-center experience of endovascular recanalization for patients with chronic symptomatic ICVA occlusion who were refractory to medical therapy. METHODS: From Jan 2009 to Jan 2017, we retrospectively reviewed 14 consecutive patients presenting with recurrent symptoms attributed to the chronic ICVA occlusion. We searched previous literature using PubMed databases during the same period as comparison...
February 1, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
Kouichi Yamamoto, Atsushi Yamatodani
INTRODUCTION: Pica behavior, kaolin ingestion, in rats and mice can be used as an assessment of nausea and vomiting; however, we observed that the incidence of pica behavior in ICR strain mice varied markedly. We investigated the susceptibility of four strains of mice (ICR, BALB/c, C57BL/6, and DBA/2) to the development of pica behavior. METHODS: Mice received cisplatin (7.5 mg/kg, i.p.) with or without a serotonin 5-HT3 receptor antagonist (granisetron: 0.1 mg/kg, i...
January 30, 2018: Journal of Pharmacological and Toxicological Methods
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