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https://www.readbyqxmd.com/read/29912478/associations-between-state-level-policies-regarding-alcohol-use-among-pregnant-women-adverse-birth-outcomes-and-prenatal-care-utilization-results-from-1972-2013-vital-statistics
#1
Meenakshi S Subbaraman, Sue Thomas, Ryan Treffers, Kevin Delucchi, William C Kerr, Priscilla Martinez, Sarah C M Roberts
BACKGROUND: Policies regarding alcohol use during pregnancy continue to be enacted and debated in the United States. However, no study to date has examined whether these policies are related to birth outcomes, the outcomes they ultimately aim to improve. Here we assessed whether state-level policies targeting alcohol use during pregnancy are related to birth outcomes, which has not been done comprehensively before. METHODS: Secondary analyses of birth certificate data from N=148,048,208 United States singleton births between 1972-2013...
June 18, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29912336/reproductive-life-in-women-with-celiac-disease-a-nationwide-population-based-matched-cohort-study
#2
L Grode, B H Bech, O Plana-Ripoll, M Bliddal, I E Agerholm, P Humaidan, C H Ramlau-Hansen
STUDY QUESTION: How does celiac disease (CD) influence women's reproductive life, both prior to and after the diagnosis? SUMMARY ANSWER: Prior to the diagnosis of CD, an increased risk of adverse pregnancy outcomes was seen, whereas after the diagnosis, no influence on reproductive outcomes was found. WHAT IS KNOWN ALREADY: CD has been associated with several conditions influencing female reproduction and pregnancy outcomes including spontaneous abortion and stillbirth...
June 15, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29909562/reporting-adverse-drug-reactions-contribution-knowledge-and-perception-of-german-pharmacy-professionals
#3
Anna Laven, Katharina Schmitz, Wilhelm-Hubertus Franzen
Background The detection, assessment and prevention of adverse drug reactions along the product's life cycle is known as pharmacovigilance. German pharmacists are obliged by law to conduct pharmacovigilance measures, a specific training is not required. Objectives To assess the knowledge, contribution and perception of German pharmacy professionals regarding pharmacovigilance activities, in order to identify their needs to report better on the issue. Setting A semi-quantitative survey among German pharmacy professionals was conducted in November 2017...
June 16, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29906490/mapping-national-surveillance-of-surgical-site-infections-ssis-to-national-needs-and-priorities-an-assessment-of-england-s-surveillance-landscape
#4
Rachael Troughton, Gabriel Birgand, Alan P Johnson, Nichola Naylor, Myriam Gharbi, Paul Aylin, Susan Hopkins, Usman Jaffer, Alison Holmes
BACKGROUND: The rise in antimicrobial resistance has highlighted the importance of surgical site infection (SSI) prevention with effective surveillance strategies playing a key role in improving patient safety. This study maps national needs and priorities for SSI surveillance against current national surveillance activity. METHODS: This study analysed SSI surveillance in NHS hospitals in England covering 23 surgical procedures. Data collected were: (i) annual number of procedures, (ii) SSI rates from national reports, (iii) national reporting requirement (mandatory, voluntary, not offered), (iv) priority ranking from a survey of 84 English NHS hospitals, (v) excess length of stay and costs from the literature...
June 12, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29901593/finite-element-based-3d-computer-modeling-for-personalized-treatment-planning-in-clubfoot-deformity-case-report-with-technique-description
#5
Horea Gozar, Zoltan Derzsi, Alexandru Chira, Örs Nagy, Theodora Benedek
RATIONALE: In clubfoot deformity, planning of corrective treatment requires a complex understanding of the foot anatomy, as well as of the geometry and distribution of altered mechanical forces acting at the level of the deformed foot. At the same time, treatment success depends largely on the selection of the most appropriate shape and angles of the customized orthesis developed for foot correction. Therefore, a complex assessment of the intensity and distribution of the mechanical forces at this site is mandatory prior to initiation of any corrective therapy...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29896557/arthroplasty-care-redesign-related-to-the-comprehensive-care-for-joint-replacement-model-results-at-a-tertiary-academic-medical-center
#6
Chancellor F Gray, Hernan A Prieto, Andrew T Duncan, Hari K Parvataneni
Background: Total joint arthroplasty (TJA) remains the highest expenditure in the Centers for Medicare and Medicaid Services (CMS) budget. One model to control cost is the Comprehensive Care for Joint Replacement (CJR) model. There has been no published literature to date examining the efficacy of CJR on value-based outcomes. The purpose of this study was to determine the efficacy and sustainability of a multidisciplinary care redesign for total joint arthroplasty under the CJR paradigm at an academic tertiary care center...
June 2018: Arthroplasty Today
https://www.readbyqxmd.com/read/29894459/conjunctival-melanoma-metastasis-to-the-contralateral-orbit
#7
Fanglin He, Yuxin Wang, Renbin Jia
BACKGROUND: Malignant melanoma predominantly occurs in whites, and is potentially fatal. Distant metastases often occur in lung, liver, brain, and could occur without prior regional disease. Conjunctival melanoma metastasis to contralateral orbit has never been reported. PATIENT PRESENTATION: A 60-year-old man who underwent a left primary conjunctival neoplasm resection 11 months ago presented for the evaluation of a conjunctival dark-colored mass with a bulging left lower eyelid that directly invaded the orbits bilaterally...
June 11, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29894342/severe-disruption-of-water-and-electrolyte-balance-after-appendectomy-a-case-report
#8
Olga Bossong, Christoph Rudin, Gabor Szinnai, Thomas O Erb, Jens Moll
Perioperative derangements of fluid and electrolyte homeostasis are rare complications in healthy children. Nonetheless, early diagnosis and treatment are mandatory to avoid a potentially life-threatening situation. However, the variety of underlying pathologies may prove to make accurate diagnosis challenging. This case report presents the management of an unexpected occurrence of a perioperative partial diabetes insipidus with massive fluid loss. Diagnostic and therapeutic procedures are discussed in the context of laboratory findings, and an overview of the existing literature is given...
June 11, 2018: A&A practice
https://www.readbyqxmd.com/read/29890558/pulmonary-co-infection-with-nocardia-species-and-nontuberculous-mycobacteria-mimicking-miliary-tuberculosis-in-a-patient-with-crohn-s-disease-under-combined-immunosuppressive-therapy
#9
Marko Weber, Jessica Rüddel, Tony Bruns, Mathias W Pletz, Andreas Stallmach
Nocardiosis is a rare infection caused by ubiquitous soil-born, acid-resistant, Gram-positive bacteria that can be life-threatening in immunocompromised patients. Originally usually diagnosed in HIV-positive patients, only few cases have been reported in patients on immunosuppressive therapy for inflammatory bowel disease or rheumatologic disorders. We present a case of a 32-year-old man who was treated with infliximab, prednisolone, and azathioprine for severe terminal ileitis. Although the clinical status improved under triple immunosuppressive therapy, weight loss, weakness, and fatigue persisted...
June 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29888384/problems-with-an-intrathecal-pump-in-a-paraplegic-scuba-diver
#10
Brahim Hacene, Nathalie Draulans, Tom Theys
Scuba diving with an intrathecal baclofen pump is encouraged for people with spinal cord injury who are suffering from spasticity. However, the diving depth is limited to 10 metres in this context. Proper physician and patient education in this respect is mandatory since non-compliance can lead to an irreversible loss of drug reservoir capacity due to collapse of the bottom shield. We report such an incident in a paraplegic diver diving to depths down to 30 metres' water.
June 30, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/29888237/diagnostic-investigations-of-gastroesophageal-reflux-disease-who-and-when-to-refer-and-for-what-test
#11
REVIEW
Arne Kandulski, Lukas Moleda, Martina Müller-Schilling
Background: Due to the high prevalence and incidence of patients with gastroesophageal reflux disease (GERD), the diagnostic workup of patients with symptoms of GERD needs to be balanced between empiric antisecretory therapy and further functional assessment including endoscopy and reflux monitoring. Methods: This article is based on a literature review (PubMed, Medline) using the terms 'gastroesophageal reflux disease' or 'GERD' and 'diagnosis', 'therapy', or 'PPI' with special and critical analysis of the current 'Porto' consensus report...
April 2018: Visceral Medicine
https://www.readbyqxmd.com/read/29887897/varicella-infection-in-the-middle-east-prevalence-complications-and-vaccination
#12
REVIEW
Mariam Al-Turab, Wassim Chehadeh
Varicella (chickenpox) is the primary infection of varicella-zoster virus (VZV), it is a mild self-limiting infection, but it is also highly contagious and can cause severe complications among high-risk group of individuals. It is usually a childhood infection providing lifelong immunity, but adults without varicella history are also susceptible to infection. High-risk group of individuals is more likely to develop serious complications. Varicella vaccine was introduced to protect this group of individuals and to prevent epidemic spread of VZV infection in a community...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29886208/case-report-of-a-large-common-hepatic-artery-aneurysm
#13
Dongheon Lee, Byeoung-Hoon Chung, Seon-Hee Heo, Yang-Jin Park, Dong-Ik Kim
Heparic artery aneurysm is rare, but appropriate treatment is mandatory. We report a 50-year-old woman with an asymptomatic large hepatic artery aneurysm. The aneurysm was found as a result of abdominal computed tomography (CT) performed as a part of the screening. An open surgery was performed due to the size of an aneurysm. Aneurysmectomy was achieved and the proper hepatic artery was anastomosed with GDA for adequate blood flow to the liver. Adequate hepatic circulation was confirmed postoperatively by duplex ultrasonography and CT...
June 7, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29880398/the-methodological-quality-of-nurse-sensitive-indicators-in-dutch-hospitals-a-descriptive-exploratory-research-study
#14
R A M M Kieft, D Stalpers, A P M Jansen, A L Francke, D M J Delnoij
OBJECTIVE: Nurse-sensitive indicators (NSIs) are increasingly being developed and used to establish quality of nursing care in Western countries. The objective was to gain insights into the methodological quality of mandatory NSIs in Dutch hospitals, including indicators for pain, wound care, malnutrition and delirium. DESIGN: A descriptive exploratory design was used, starting with desk research into publicly available documents and reports describing the development of the NSIs included in this study...
June 1, 2018: Health Policy
https://www.readbyqxmd.com/read/29879426/re-emergence-of-human-t-lymphotropic-viruses-in-west-africa
#15
REVIEW
Nneoma Confidence JeanStephanie Anyanwu, Elijah Ekah Ella, Aghogho Ohwofasa, Maryam Aminu-Mukhtar
Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distribution of the virus types and significance of frequent indeterminate reports, while highlighting the need for mandatory routine blood screening. Capturing relevant data from discovery till date, sources searched were Google Scholar, CrossRef, NCBI (PubMed), MEDLINE, Research Gate, Mendeley, abstracts of Conferences and Proceedings, organization websites and reference lists of selected papers...
June 4, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29878838/ecologically-relevant-episodic-memory-assessment-indicates-an-attenuated-age-related-memory-loss-a-virtual-reality-study
#16
Marlon O Pflueger, Rolf-Dieter Stieglitz, Patrick Lemoine, Thomas Leyhe
OBJECTIVES: Since the advent of imaging techniques, the role of the neuropsychological assessment has changed. Questions concerning everyday functionality became primarily important and, thus, ecologically valid neuropsychological assessments are mandatory. Virtual reality (VR) environments might provide a way of implementing immersive cognitive assessments with a higher degree of everyday-life-related cognitive demands. METHOD: We report on a VR-based episodic memory examination in N = 30 young and N = 18 healthy older adults (HOA) using a kitchen scene...
June 7, 2018: Neuropsychology
https://www.readbyqxmd.com/read/29876100/social-media-posts-and-online-search-behaviour-as-early-warning-system-for-mrsa-outbreaks
#17
Tom H van de Belt, Pieter T van Stockum, Lucien J L P G Engelen, Jules Lancee, Remco Schrijver, Jesús Rodríguez-Baño, Evelina Tacconelli, Katja Saris, Marleen M H J van Gelder, Andreas Voss
Background: Despite many preventive measures, outbreaks with multi-drug resistant micro-organisms (MDROs) still occur. Moreover, current alert systems from healthcare organizations have shortcomings due to delayed or incomplete notifications, which may amplify the spread of MDROs by introducing infected patients into a new healthcare setting and institutions. Additional sources of information about upcoming and current outbreaks, may help to prevent further spread of MDROs.The study objective was to evaluate whether methicillin-resistant Staphylococcus aureus (MRSA) outbreaks could be detected via social media posts or online search behaviour; if so, this might allow earlier detection than the official notifications by healthcare organizations...
2018: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29872509/a-quality-analysis-of-clinical-anaesthesia-study-protocols-from-the-chinese-clinical-trials-registry-according-to-the-spirit-statement
#18
Lei Yang, Shouming Chen, Di Yang, Jiajin Li, Taixiang Wu, Yunxia Zuo
Objective: To learn about the overall quality of clinical anaesthesia study protocols from the Chinese Clinical Trials Registry and to discuss the way to improve study protocol quality. Methods: We defined completeness of each sub-item in SPIRIT as N/A (not applicable) or with a score of 0, 1, or 2. For each protocol, we calculated the proportion of adequately reported items (score = 2 and N/A) and unreported items (score = 0). Protocol quality was determined according to the proportion of reported items, with values >50% indicating high quality...
May 15, 2018: Oncotarget
https://www.readbyqxmd.com/read/29863722/-the-coroner-s-autopsies-in-the-great-britain-the-problems-related-to-the-quality-of-the-studies-standardization-auditing-financial-support-and-the-approaches-to-their-solution
#19
I Yu Makarov, T A Kuprina, V A Fetisov, P V Minaeva
This article continues the series of previous publications of the authors based on the analysis of the detailed report of the experts of the National Confidential Enquiry into Patient Outcome and Death program (NCEPOD) designed to evaluate the quality of autopsies carried out by the coroners in the Great Britain. It was shown that only in 13 to 55% of the 1,691 case the operators had an opportunity to refer the necropsy materials for the pathological study. The problems encountered in association with histological and toxicological analysis arose from the misunderstanding between the coroners and the pathologists as regard the organizational aspects of autopsy studies as swell as the financial and economic considerations...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29861877/snps-in-predicting-clinical-efficacy-and-toxicity-of-chemotherapy-walking-through-the-quicksand
#20
REVIEW
Raffaele Palmirotta, Claudia Carella, Erica Silvestris, Mauro Cives, Stefania Luigia Stucci, Marco Tucci, Domenica Lovero, Franco Silvestris
In the "precision medicine" era, chemotherapy still remains the backbone for the treatment of many cancers, but no affordable predictors of response to the chemodrugs are available in clinical practice. Single nucleotide polymorphisms (SNPs) are gene sequence variations occurring in more than 1% of the full population, and account for approximately 80% of inter-individual genomic heterogeneity. A number of studies have investigated the predictive role of SNPs of genes enrolled in both pharmacodynamics and pharmacokinetics of chemotherapeutics, but the clinical implementation of related results has been modest so far...
May 18, 2018: Oncotarget
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