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https://www.readbyqxmd.com/read/29665806/awareness-understanding-and-use-of-sodium-information-labelled-on-pre-packaged-food-in-beijing-a-cross-sectional-study
#1
Yao He, Liping Huang, Sijin Yan, Yuan Li, Lixin Lu, Hongbo Wang, Wenyi Niu, Puhong Zhang
BACKGROUND: Nutrition labelling has been mandatory for pre-packaged foods since 2013 in China, and sodium is one of the nutrients required for display on the nutritional information panel (NIP). This study aimed to estimate the awareness, understanding of, and use of sodium labelling information among the population in China. METHODS: A cross-sectional survey was carried out in urban Beijing in 2016 on pre-packaged foods. The researchers randomly selected 380 residents from four convenient but disconnected communities and 370 shoppers from four supermarkets owned by different companies and conducted face-to-face interviews...
April 17, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29660566/extrapleural-solitary-fibrous-tumor-a-distinct-entity-from-pleural-solitary-fibrous-tumor-an-update-on-clinical-molecular-and-diagnostic-features
#2
REVIEW
Andrea Ronchi, Immacolata Cozzolino, Federica Zito Marino, Marina Accardo, Marco Montella, Iacopo Panarese, Giuseppe Roccuzzo, Giorgio Toni, Renato Franco, Annarosaria De Chiara
Solitary fibrous tumor (SFT) is a mesenchymal neoplasm that was originally described to be localized in the pleura, but thereafter, this has been reported in several anatomic sites. Although the etiology of the neoplasm remains largely unknown, the pathogenesis seems to be related to an NAB2-STAT6 fusion gene due to paracentric inversion on chromosome 12q13. The diagnosis of extrapleural SFT is challenging, owing to its rarity, and requires an integrated approach that includes specific clinical, histological, immunohistochemical, and even molecular findings...
April 9, 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29660175/redox-switchable-calix-6-arene-based-isomeric-rotaxanes
#3
Valeria Zanichelli, Margherita Bazzoni, Arturo Arduini, Paola Franchi, Marco Lucarini, Giulio Ragazzon, Andrea Secchi, Serena Silvi
Operating molecular machines are based on switchable systems, whose components can be set in motion in a controllable fashion. The presence of non-symmetric elements is a mandatory requirement to obtain and demonstrate the unidirectionality of motion. Calixarene-based macrocycles have proven very efficient hosts in the design of oriented rotaxanes and of pseudorotaxanes with a strict control on the direction of complexation. We have synthesized and characterized a series of two-station rotaxanes based on bypiridinium-ammonium axles...
April 16, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29658394/management-of-staghorn-renal-stones
#4
Akif Diri, Banu Diri
Staghorn stones are large branching stones that fill part of all of the renal pelvis and renal calyces and they can be complete or partial depending on the level of occupancy of the collecting system. Although kidney stones are commoner in men, staghorn stones are less often reported in men compared to women and they are usually unilateral. Due to the significant morbidity and potential mortality attributed to staghorn stones, prompt assessment and treatment is mandatory. Conversely, conservative treatment has been shown to carry a mortality rate of 28% in 10-year period and 36% risk of developing significant renal impairment...
November 2018: Renal Failure
https://www.readbyqxmd.com/read/29658352/chronic-subdural-collection-overlying-an-intra-axial-hemorrhagic-lesion-in-chronic-myelomonocytic-leukemia-special-report-and-review-of-the-literature
#5
Anne-Laure Bernat, Stefano Maria Priola, Ahmad Elsawy, Faisal Farrash, Shervin Taslimi, Fred Gentili
Chronic myelomonocytic leukaemia (CMML) is a clonal hematopoietic stem cell disorder characterized by the presence of an absolute monocytosis in the peripheral blood (>1 x 109 /L) and the presence of myelodysplastic and myeloproliferative features in the bone marrow. Involvement of the central nervous system (CNS) is uncommon in CMML. Areas covered: Herein described is a case report of a CMML patient who presents with symptomatic chronic subdural collection overlying a haemorrhagic brain lesion, along with diffuse dural infiltration, after two cycles of azacytidine...
April 16, 2018: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29657505/knowledge-and-attitude-of-health-care-professionals-toward-adverse-drug-reactions-reporting-at-king-saud-medical-city
#6
Khaja Moinuddin, Sheraz Ali, Amal Qadri Al-Aqqad, Sara Osama Salem, Maram Abdullah Al-Dossari, Abdullah Mohammad Ananzeh, Jaffer Bin Baqar
Background: Health-care professionals across the globe are obligated to report adverse drug reactions (ADRs). The knowledge of ADRs and attitude of health-care professionals toward ADRs reporting is vital for patient safety. This study intends to investigate the knowledge of ADRs and attitude of health-care professionals toward ADRs reporting. Materials and Methods: A cross-sectional study using an anonymous questionnaire was conducted over a period of 3 months (September 2016 to November 2016) at King Saud Medical City, Riyadh, Saudi Arabia...
January 2018: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29656748/nivolumab-induced-severe-pancytopenia-in-a-patient-with-lung-adenocarcinoma
#7
Kentaro Tokumo, Takeshi Masuda, Takahiko Miyama, Shinichiro Miura, Kakuhiro Yamaguchi, Shinjiro Sakamoto, Yasushi Horimasu, Taku Nakashima, Shintaro Miyamoto, Takashi Yoshida, Hiroshi Iwamoto, Kazunori Fujitaka, Hironobu Hamada, Noboru Hattori
Severe leukopenia, thrombocytopenia, and bi-cytopenia due to nivolumab have been reported. In this report, we present the first case of nivolumab-induced severe pancytopenia in a patient with lung adenocarcinoma. A 56-year-old Japanese man with lung adenocarcinoma received nivolumab therapy as second-line treatment. After 3 cycles of this therapy, although computed tomography (CT) showed a reduced tumor size, laboratory findings revealed pancytopenia and a bone marrow biopsy showed a severely hypoplastic marrow...
May 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29652684/biphasic-cuirass-ventilation-during-anesthesia-for-tracheobronchial-stent-insertion-or-removal-by-a-rigid-bronchoscope-a-case-report
#8
Hideaki Mori, Atsuko Shono, Ritsuko Hirade, Tetsuro Nikai, Yoji Saito
Airway management and ventilation during a tracheobronchial stenting procedure are challenging given that mandatory positive pressure ventilation cannot be fully achieved while using a rigid bronchoscope due to leakage from the scope tip. Biphasic cuirass ventilation is a negative pressure ventilation method using an external cuirass fitted to the anterior chest, which could assist in spontaneous breathing and ventilation support. We report 3 successful anesthesia cases in which we could maintain adequate ventilation and oxygenation, supported by biphasic cuirass ventilation, in patients undergoing tracheobronchial stent placement or removal procedures using rigid bronchoscopy...
April 15, 2018: A&A practice
https://www.readbyqxmd.com/read/29643815/mechanical-characterization-of-the-vessel-wall-by-data-assimilation-of-intravascular-ultrasound-studies
#9
Gonzalo D Maso Talou, Pablo J Blanco, Gonzalo D Ares, Cristiano Guedes Bezerra, Pedro A Lemos, Raúl A Feijóo
Atherosclerotic plaque rupture and erosion are the most important mechanisms underlying the sudden plaque growth, responsible for acute coronary syndromes and even fatal cardiac events. Advances in the understanding of the culprit plaque structure and composition are already reported in the literature, however, there is still much work to be done toward in-vivo plaque visualization and mechanical characterization to assess plaque stability, patient risk, diagnosis and treatment prognosis. In this work, a methodology for the mechanical characterization of the vessel wall plaque and tissues is proposed based on the combination of intravascular ultrasound (IVUS) imaging processing, data assimilation and continuum mechanics models within a high performance computing (HPC) environment...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29630050/a-minimally-invasive-model-to-analyze-endochondral-fracture-healing-in-mice-under-standardized-biomechanical-conditions
#10
Tina Histing, Philipp Bremer, Mika F Rollmann, Steven Herath, Moritz Klein, Tim Pohlemann, Michael D Menger, Tobias Fritz
Bone healing models are necessary to analyze the complex mechanisms of fracture healing to improve clinical fracture treatment. During the last decade, an increased use of mouse models in orthopedic research was noted, most probably because mouse models offer a large number of genetically-modified strains and special antibodies for the analysis of molecular mechanisms of fracture healing. To control the biomechanical conditions, well-characterized osteosynthesis techniques are mandatory, also in mice. Here, we report on the design and use of a closed bone healing model to stabilize femur fractures in mice...
March 22, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29627780/double-venous-compression-due-to-duplicated-inferior-vena-cava-induced-right-common-iliac-vein-thrombosis
#11
Yuichi Mukai, Shuhei Nozawa, Toshiro Suzuki
Venous compression syndromes are caused by extrinsic venous compression of anatomical structures, such as the adjacent arteries and bones. Chronic venous compression and pulsative vibratory arterial pressure accelerate the development of deep vein thrombosis. Herein, we report the first case of double venous compressions due to a duplicated inferior vena cava-induced right-sided common iliac vein thrombosis. The thrombus was induced by left-sided inferior vena cava entrapment and right-sided common iliac vein compression, resembling nutcracker syndrome and May-Thurner syndrome, respectively...
April 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29625790/transfusion-associated-hazards-a-revisit-of-their-presentation
#12
O Garraud, C Sut, A Haddad, S Tariket, C Aloui, S Laradi, H Hamzeh-Cognasse, T Bourlet, F Zeni, C Aubron, Y Ozier, S Laperche, T Peyrard, P Buffet, D Guyotat, E Tavernier, F Cognasse, B Pozzetto, G Andreu
As a therapy or a support to other therapies, despite being largely beneficial to patients in general, transfusion it is not devoid of some risks. In a moderate number of cases, patients may manifest adverse reactions, otherwise referred to as transfusion-associated hazards (TAHs). The latest French 2016 haemovigilance report indicates that 93% of TAHs are minor (grade 1), 5.5% are moderate (grade 2) and 1.6% are severe (grade 3), with only five deaths (grade 4) being attributed to transfusion with relative certainty (imputability of level [or grade] 1 to 3)...
April 3, 2018: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29625572/standardized-patients-in-psychiatry-the-best-way-to-learn-clinical-skills
#13
Monika Himmelbauer, Tamara Seitz, Charles Seidman, Henriette Löffler-Stastka
BACKGROUND: Standardized patients (SP) have been successfully utilized in medical education to train students' communication skills. At the Medical University of Vienna communication training with SPs in psychiatry is a mandatory part of the curriculum. In the training, the SP plays the role of four different patients suffering from depression/suicidal tendencies, somatoform disorder, anxiety disorder, or borderline disorder while the student attempts to gather the patient's medical history...
April 6, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29624208/gemcitabine-based-chemotherapy-for-advanced-biliary-tract-carcinomas
#14
REVIEW
Omar Abdel-Rahman, Zeinab Elsayed, Hesham Elhalawani
BACKGROUND: Biliary tract cancers are a group of rare heterogeneous malignant tumours. They include intrahepatic and extrahepatic cholangiocarcinomas, gallbladder carcinomas, and ampullary carcinomas. Surgery remains the optimal modality of therapy leading to long-term survival for people diagnosed with resectable biliary tract carcinomas. Unfortunately, most people with biliary tract carcinomas are diagnosed with either unresectable locally-advanced or metastatic disease, and they are only suitable for palliative chemotherapy or supportive care...
April 6, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29623468/misses-and-near-misses-in-diagnosing-nodular-fasciitis-and-morphologically-related-reactive-myofibroblastic-proliferations-experience-of-a-referral-center-with-emphasis-on-frequency-of-usp6-gene-rearrangements
#15
Ramona Erber, Abbas Agaimy
Although harmless, reactive and benign neoplastic myo-/fibroblastic proliferations represent a diagnostic challenge in routine surgical pathology practice as reflected by their frequency among consultation cases. In addition to resembling each other, the prototypical nodular fasciitis (NF) and NF-like lesions can be mistaken for low-grade or aggressive sarcomas. USP6 translocation was reported recently as the molecular driver and potential diagnostic marker of NF. We reviewed 71 lesions with a diagnosis of NF (n = 48) or NF-like myofibroblastic proliferations (n = 23) and screened them for USP6 translocation by fluorescence in situ hybridization (FISH)...
April 5, 2018: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/29623467/allogeneic-haematopoietic-cell-transplantation-offers-the-chance-of-cure-for-patients-with-transformed-follicular-lymphoma
#16
Frank Heinzelmann, Wolfgang Bethge, Dietrich Wilhelm Beelen, Matthias Stelljes, Peter Dreger, Marianne Engelhard, Jürgen Finke, Nikolaus Kröger, Ernst Holler, Martin Bornhäuser, Annerose Müller, Imme Haubitz, Hellmut Ottinger
PURPOSE: In patients with follicular lymphoma, secondary transformation to aggressive lymphoma (tFL) implies a poor prognosis. In principle, allogeneic haematopoietic cell transplantation (allo-HCT) offers a chance of cure for tFL but is rarely practiced. Aim of this retrospective multicenter study was to define the actual significance of allo-HCT in treatment of tFL. METHODS: The database of the German Registry for Stem Cell Transplantation (DRST) was screened for patients who underwent allo-HCT for tFL 1998-2008...
April 5, 2018: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/29619213/pet-owner-and-vet-interactions-exploring-the-drivers-of-amr
#17
Matt Smith, Caroline King, Mark Davis, Adele Dickson, Jeni Park, Fraser Smith, Kay Currie, Paul Flowers
Background: Antimicrobial resistance (AMR) is a growing public health problem across the world. As the negative consequences of AMR become apparent at local, national and international levels, more attention is being focussed on the variety of mechanisms by which AMR is potentiated. We explore how interactions between pet owners and veterinarians represent a key arena in which AMR-related behaviours can be shaped. Methods: In depth semi-structured interviews were carried out with pet owners ( n  = 23) and vets ( n  = 16) across the UK in 2017...
2018: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/29618346/diagnosis-and-management-of-a-mediastinal-ectopic-thyroid-laying-on-the-right-bronchus-case-report-and-review-of-literature
#18
Alessio Metere, Tiziano De Giacomo, Massimo Vergine, Marco Biffoni, Laura Giacomelli
BACKGROUND: The mediastinal ectopic thyroid is very rare, accounting for less than 1% of all cases of ectopic thyroid tissue. The differential diagnoses with other diseases such as lymphomas, thymic tumors and dermoid cysts is mandatory, in fact each one, needs different management and treatment. CASE PRESENTATION: Here, we discuss a rare case of mediastinal ectopic thyroid presenting with a paratracheal mass laying on the right bronchus without symptoms. A 63-year-old male presented with an abnormal well-defined mass along the right paratracheal side, detected by chest x-ray...
April 4, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29618105/physician-time-burden-associated-with-querying-prescription-drug-monitoring-programs
#19
Marcus A Bachhuber, Brendan Saloner, Marc LaRochelle, Jessica S Merlin, Brandon C Maughan, Dan Polsky, Naum Shaparin, Sean M Murphy
Objective: Prescription drug monitoring programs (PDMPs) enable prescribers to review patient prescription histories, and their use is mandatory in many states. We estimated the cost of physicians retrieving PDMP patient reports compared with a model where a delegate (i.e., administrative staff) retrieves reports. Methods: We performed a cost analysis with a one-year time horizon, from the perspective of physicians' employers. We obtained specialty-specific estimates of controlled substance prescribing frequency from the National Ambulatory Medical Care Survey, 2012-2014...
March 30, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29616107/awareness-of-hepatic-arterial-variants-is-required-in-surgical-oncology-decision-making-strategy-case-report-and-review-of-literature
#20
Robert Sitarz, Monika Berbecka, Jerzy Mielko, Karol Rawicz-Pruszyński, Grzegorz Staśkiewicz, Ryszard Maciejewski, Wojciech Polkowski
Surgery for the treatment of pancreatic cancer remains the gold standard, however, the identification of the vascular supply of the pancreas and the nearby organs remains a crucial difficulties in a curative resection. During pancreatic head resection for carcinoma dissection of regional arterial vasculature is mandatory. Normal coeliac and hepatic arterial anatomy occurs in ~50-70% of patients and multiple variations have been described. Knowledge of multiple arterial anomalies is essential in hepato-pancreatico-billary surgery to avoid unnecessary complications...
May 2018: Oncology Letters
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