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https://www.readbyqxmd.com/read/28515109/updated-review-of-prevalence-of-major-risk-factors-and-use-of-screening-tests-for-cancer-in-the-united-states
#1
Ann Goding Sauer, Rebecca L Siegel, Ahmedin Jemal, Stacey A Fedewa
Much of the suffering and death from cancer could be prevented by more systematic efforts to reduce tobacco use and obesity, improve diet, and increase physical activity and use of established vaccines and screening tests. Monitoring the prevalence of cancer risk factors and preventive tests helps guide cancer prevention and early detection efforts. We provide an updated review, using data through 2015, of the prevalence of major risk factors, cancer screening, and vaccination for U.S. adults and youth. Cigarette smoking among adults decreased to 15...
May 17, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28511636/hpv-prevalence-and-type-distribution-in-cypriot-women-with-cervical-cytological-abnormalities
#2
George Krashias, Dana Koptides, Christina Christodoulou
BACKGROUND: Human papillomavirus (HPV) is the most common sexually transmitted agent, and it can cause cervical lesions and cancer in females. Currently, information regarding the prevalence of HPV in Cyprus is lacking. The aim of this study was to evaluate the HPV type-specific prevalence in 596 women, aged 19-65 years, with cytological abnormalities. Additionally, in a subset of 348 women for whom cytology results of the Pap test were available, the association between HPV infection and cervical disease was investigated...
May 16, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28511391/utility-of-modified-ultrafast-papanicolaou-stain-in-cytological-diagnosis
#3
Prachi Sinkar, Surekha Ulhas Arakeri
INTRODUCTION: Need for minimal turnaround time for assessing Fine Needle Aspiration Cytology (FNAC) has encouraged innovations in staining techniques that require lesser staining time with unequivocal cell morphology. The standard protocol for conventional Papanicolaou (PAP) stain requires about 40 minutes. To overcome this, Ultrafast Papanicolaou (UFP) stain was introduced which reduces staining time to 90 seconds and also enhances the quality. However, reagents required for this were not easily available hence, Modified Ultrafast Papanicolaou (MUFP) stain was introduced subsequently...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28503527/postactivation-potentiation-in-elite-young-soccer-players
#4
Adriano Titton, Emerson Franchini
The aim of this study was to investigate the acute effects of 16 different combinations to cause the postactivation potentiation (PAP) in elite young soccer players. Squat exercise in 4 different intensities (40%, 60%, 80%, and 100% one-repetition maximum [1RM]) was performed and its effects were evaluated in the performance of countermovement jump (CMJ), after 4 different recovery times (1, 3, 5, and 10 min). For this purpose, 25 young soccer players, underwent five experimental sessions. At the first session the control to determine 1RM in half-squat was carried out...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28502575/national-assessment-of-hpv-and-pap-tests-changes-in-cervical-cancer-screening-national-health-interview-survey
#5
Meg Watson, Vicki Benard, Jessica King, Anatasha Crawford, Mona Saraiya
BACKGROUND: Major organizations recommend cytology screening (Pap test) every 3years for women aged 21-65; women aged 30 to 65 have the option of adding the HPV test (co-test) every 5years. We examined national percentages of cervical cancer screening, and we examined use of co-testing as an option for screening. METHODS: We used 2015 U.S. National Health Interview Survey (NHIS) data to examine recent cervical cancer screening (Pap test within 3years among women aged 21-65 without a hysterectomy; N=10,596) and co-testing (N=9,125)...
May 11, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28497166/biomechanical-evaluation-of-straight-antegrade-nailing-in-proximal-humeral-fractures-the-rationale-of-the-proximal-anchoring-point
#6
Simon A Euler, Maximilian Petri, Melanie B Venderley, Grant J Dornan, Werner Schmoelz, Travis Lee Turnbull, Michael Plecko, Franz S Kralinger, Peter J Millett
PURPOSE: Varus failure is one of the most common failure modes following surgical treatment of proximal humeral fractures. Straight antegrade nails (SAN) theoretically provide increased stability by anchoring to the densest zone of the proximal humerus (subchondral zone) with the end of the nail. The aim of this study was to biomechanically investigate the characteristics of this "proximal anchoring point" (PAP). We hypothesized that the PAP would improve stability compared to the same construct without the PAP...
May 11, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28489415/hepatic-steatosis-accompanies-pulmonary-alveolar-proteinosis
#7
Alan N Hunt, Anagha Malur, Tual Monfort, Pavlos Lagoudakis, Sumeet Mahajan, Anthony D Postle, Mary Jane Thomassen
Maintenance of tissue-specific organ lipid compositions characterises mammalian lipid homeostasis. Lung and liver synthesise mixed phosphatidylcholine (PC) molecular species subsequently "tailored" for function. Lungs progressively enrich disaturated PC (DSPC) directed to lamellar body (LB) surfactant stores prior to secretion. Liver accumulates polyunsaturated PC directed to VLDL assembly and secretion, or triglyceride stores. In each tissue, selective PC species enrichment mechanisms lie at the heart of effective homeostasis...
May 10, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28486237/evaluating-the-age-cutoff-criterion-for-reporting-benign-appearing-endometrial-cells-in-routine-pap-tests-an-8-year-retrospective-review
#8
Zakaria Grada, Cherie Paquette, Claire M Eklund, Cunxian Zhang, C James Sung, Margaret Steinhoff, M Ruhul Quddus
OBJECTIVE: The 2014 Bethesda System recommends that benign-appearing endometrial cells (BECs) in routine Pap tests should be reported in patients aged ≥45 years. This is a change from previous guidelines to report BECs in women ≥40 years of age. BECs are reported to have 1% chance of endometrial lesion on follow-up. This study tests whether the new threshold may increase the specificity of the test for the detection of clinically significant endometrial lesions. STUDY DESIGN: After institutional review board approval, 1,177 BECs, reported during an 8-year study period in patients aged ≥40 years, were retrieved from 672,000 routine ThinPrep Pap tests...
May 10, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28482331/biochemical-characterization-of-the-triticale-tspap1-a-new-type-of-plant-prolyl-aminopeptidase-and-its-impact-on-proline-content-and-flowering-time-in-transgenic-arabidopsis-plants
#9
Edyta Zdunek-Zastocka, Agnieszka Grabowska, Tomasz Branicki, Beata Michniewska
Proline aminopeptidase (PAP, EC 3.4.11.5) is the only enzyme that effectively releases proline from the N-termini of peptides. The amino acid sequence of the PAP from Triticosecale, TsPAP1, comprises conserved regions, characteristic of the monomeric forms of PAP found in bacteria but not yet identified in plants. Therefore, we aimed to obtain and biochemically characterize the TsPAP1 protein. The recombinant TsPAP1 protein was received through heterologous expression of the TsPAP1 coding sequence in a bacterial expression system and purified with affinity chromatography...
April 27, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28479075/-pap-smear-before-25-years-old
#10
A Rousselin, L Dion, A Racin, V Lavoué, J Levêque, K Nyangoh Timoh
OBJECTIVES: Current French recommendations advocate cervical-vaginal screening for cervical cancer from age 25 whereas earlier screening is mostly found in current clinical practice although its consequences are not well understood. METHODS: A literature review using the MedLine database on the natural history of HPV infections, cytological screening, management of cytological and histological anomalies in adolescents and young women. RESULTS: The adolescent and young woman have some characteristics that distinguish them from adult women: a high prevalence of HPV infections (making the use of the HPV test unprofitable), accompanied by a higher clearance; frequency of minor cytological abnormalities (for which a cytological surveillance without colposcopy is sufficient) and low-grade histological lesions of low grade the usual prognosis of which is complete recovery; and rarity of CIN3 lesions and absence of invasive lesions, allowing no treatment in patients with CIN2 lesions and compliant to cytological and colposcopic surveillance...
May 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/28473240/cervical-cancer-screening-and-incidence-by-age-unmet-needs-near-and-after-the-stopping-age-for-screening
#11
Mary C White, Meredith L Shoemaker, Vicki B Benard
INTRODUCTION: Leading professional organizations recommend cervical cancer screening for average-risk women aged 21-65 years. For average-risk women aged >65 years, routine screening may be discontinued if "adequate" screening with negative results is documented. Screening is recommended after age 65 years for women who do not meet adequate prior screening criteria or are at special risk. METHODS: Authors examined the most recent cervical cancer incidence data from two federal cancer surveillance programs for all women by age and race, corrected for hysterectomy status...
April 26, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28471315/assessing-perceived-benefits-barriers-and-self-efficacy-for-cervical-cancer-screening-among-korean-american-women
#12
Wei-Chen Tung, Minggen Lu, Michelle Granner, Jeeyun Sohn
A large proportion of Korean American women (KAW) do not receive regular cervical cancer screening. Self-report data from 102 KAW were analyzed by multiple linear regressions. Compared to women in action/maintenance, women in precontemplation/relapse stages were less likely to agree that a Pap test is important for health and were more likely to endorse barriers to testing (cost, not having a female doctor, preference for Korean medicine). Women in precontemplation/relapse also reported lower scores on self-efficacy items (travel large distances, pain perceptions, financial costs, time)...
May 4, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28469755/can-different-complex-training-improve-the-individual-phenomenon-of-post-activation-potentiation
#13
Zong-Rong Chen, Shin-Liang Lo, Min-Hsien Wang, Ching-Fang Yu, Hsien-Te Peng
The aims of the present study were (a) to determine whether the two types of complex training and vibration complex training would improve the individual phenomenon of post-activation potentiation (PAP) for every athlete in a team setting; and (b) to compare the acute effect of resistance and plyometric exercise, whole body vibration, complex training and vibration complex training on vertical jump performance. The participants were ten male division I college volleyball and basketball players. They were asked to perform three vertical jumps as a pre-test and were then randomly assigned to one of five PAP protocols, resistance exercise using half squat exercise, plyometric exercise using drop jumps with individualized drop height, whole body vibration using squats on a vibration plate, complex training combining resistance exercise with plyometric exercise, vibration complex training combining whole body vibration with plyometric exercise...
February 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28469362/predictors-of-colorectal-cancer-screening-awareness-among-people-working-in-a-hospital-environment
#14
Spyridon Michopoulos, Efstathios Manios, Helias Kourkoutas, Konstantinos Argyriou, Georgios Leonidakis, Evanthia Zampeli, Kimon Stamatelopoulos, Athanasios-Meletios Dimopoulos
BACKGROUND: Compliance rates for colorectal cancer (CRC) screening are much lower than those desired. Appropriate information on CRC risks and screening methods is supposed to stimulate motivation for screening. We aimed to identify parameters associated with the decision for CRC screening and colonoscopy in a population expected to have high awareness of disease prevention. METHODS: In a single-center, cross-sectional study, we used an anonymous questionnaire (AQ) to record the demographics, habits and screening behavior for cancers and other common diseases of all employees older than 50 years in our hospital...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28469316/cervical-cytopathological-changes-among-women-with-vaginal-discharge-attending-teaching-hospital
#15
Magdi M Salih, Fatma Tage El Sir AlHag, Mohammed Ahmed Khalifa, Abdulla H El Nabi
AIMS: To find cytology changes among women attending obstetrics and gynaecology clinic with complaints of vaginal discharges. SETTINGS AND DESIGN: This descriptive hospital-based cytological study was conducted at the outpatient clinic of the obstetrics and gynaecology department. MATERIALS AND METHODS: Two hundred women with complaints of vaginal discharge were selected. Their detailed histories were documented on a special request form. Pap smears were then obtained and sent for cytological examination to the cytopathology department...
April 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28455957/ras-testing-and-cetuximab-treatment-for-metastatic-colorectal-cancer-a-cost-effectiveness-analysis-in-a-setting-with-limited-health-resources
#16
Bin Wu, Yuan Yao, Ke Zhang, Xuezhen Ma
PURPOSE: To test the cost-effectiveness of cetuximab plus irinotecan, fluorouracil, and leucovorin (FOLFIRI) as first-line treatment in patients with metastatic colorectal cancer (mCRC) from a Chinese medical insurance perspective. RESULTS: Baseline analysis showed that the addition of cetuximab increased quality-adjusted life-years (QALYs) by 0.63, an increase of $17,086 relative to FOLFIRI chemotherapy, resulting in an incremental cost-effectiveness ratio (ICER) of $27,145/QALY...
April 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28455671/perceptions-of-cervical-cancer-screening-screening-behavior-and-post-migration-living-difficulties-among-bhutanese-nepali-refugee-women-in-the-united-states
#17
Jennifer Kue, Heather Hanegan, Alai Tan
Bhutanese-Nepali refugees are one of the largest refugee groups to be resettled in the U.S. in the past decade. Cervical cancer is a leading cause of cancer disparity in this population, yet screening rates are suboptimal. Nepali-speaking interviewers administered a community health needs questionnaire to a convenience sample of Bhutanese-Nepali refugees in a Midwestern city between July to October of 2015. Descriptive statistics were used to describe socio-demographic characteristics, Pap smear beliefs, post-migration living difficulties, and screening status...
April 28, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28455223/a-longitudinal-assessment-of-adherence-to-breast-and-cervical-cancer-screening-recommendations-among-women-with-and-without-intellectual-disability
#18
Xinling Xu, Suzanne W McDermott, Joshua R Mann, James W Hardin, Chelsea B Deroche, Dianna D Carroll, Elizabeth A Courtney-Long
Each year in the United States, about 4000 deaths are attributed to cervical cancer, and over 40,000 deaths are attributed to breast cancer (U.S. Cancer Statistics Working Group, 2015). The purpose of this study was to identify predictors of full, partial, and no screening for breast and cervical cancer among women with and without intellectual disability (ID) who are within the age group for screening recommended by the U.S. Preventive Service Task Force (USPSTF), while accounting for changes in recommendations over the study period...
April 25, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28454338/ellagic-acid-and-annona-muricata-in-the-chemoprevention-of-hpv-related-pre-neoplastic-lesions-of-the-cervix
#19
Giulia Morosetti, Anna Angela Criscuolo, Flavia Santi, Carlo Federico Perno, Emilio Piccione, Marco Ciotti
Ellagic acid is a phenolic compound naturally present in nuts and berries. Several studies have demonstrated that this bioactive compound has antioxidant, chemopreventive and antiviral activity. Annona muricata is a type of fruit tree with a long history of traditional use. A number of properties have been attributed to different parts of the plant, including anticancer and antioxidant activities. In the current study, a complex based on ellagic acid, Annona Muricata and antioxidant factors (an ellagic acid complex) was administered to a group of human papilloma virus (HPV) infected women with and without cervical lesions, for 12 months...
March 2017: Oncology Letters
https://www.readbyqxmd.com/read/28453530/intracellular-signaling-entropy-can-be-a-biomarker-for-predicting-the-development-of-cervical-intraepithelial-neoplasia
#20
Masakazu Sato, Kei Kawana, Katsuyuki Adachi, Asaha Fujimoto, Mitsuyo Yoshida, Hiroe Nakamura, Haruka Nishida, Tomoko Inoue, Ayumi Taguchi, Juri Ogishima, Satoko Eguchi, Aki Yamashita, Kensuke Tomio, Osamu Wada-Hiraike, Katsutoshi Oda, Takeshi Nagamatsu, Yutaka Osuga, Tomoyuki Fujii
While the mortality rates for cervical cancer have been drastically reduced after the introduction of the Pap smear test, it still is one of the leading causes of death in women worldwide. Additionally, studies that appropriately evaluate the risk of developing cervical lesions are needed. Therefore, we investigated whether intracellular signaling entropy, which is measured with microarray data, could be useful for predicting the risks of developing cervical lesions. We used three datasets, GSE63514 (histology), GSE27678 (cytology) and GSE75132 (cytology, a prospective study)...
2017: PloS One
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