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https://www.readbyqxmd.com/read/28430679/cervicovaginal-levels-of-human-%C3%AE-defensin-1-2-3-and-4-of-reproductive-aged-women-with-chlamydia-trachomatis-infection
#1
Nathália Mayumi Noda-Nicolau, Larissa Brito Bastos, Aline Nascimento Bolpetti, Gabriel Vitor Silva Pinto, Larissa Doddi Marcolino, Camila Marconi, Carolina Sanitá Tafner Ferreira, Jossimara Polettini, Eliane Passarelli Vieira, Márcia Guimarães da Silva
OBJECTIVE: This study included women attending primary health care units in Botucatu, São Paulo, Brazil, to assess the cervicovaginal levels of human β-defensin (hBD) 1, 2, 3, and 4 during Chlamydia trachomatis infection. PATIENTS AND METHODS: Cervicovaginal samples were collected for Pap testing and assessing the presence of infection by C. trachomatis, human papillomavirus, Neisseria gonorrhoeae, and Trichomonas vaginalis. Vaginal smears were taken to evaluate local microbiota...
April 21, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28428646/-hpv-vaccination-active-offer-in-an-italian-region
#2
Elisa Terracciano, Gian Loreto D'Alò, Silvia Aquilani, Anna Maria Aversa, Giuseppina Bartolomei, Maria Gabriella Calenda, Raffaele Catapano, Silvio Compagno, Piera Della Rovere, Angelo Fraioli, Roberto Ieraci, Daniela Reggiani, Stefano Sgricia, Antonietta Spadea, Laura Zaratti, Elisabetta Franco
Human Papillomavirus is responsible for 4.8% of cancers, and is the main cause of cervical cancer. Cervical cancer can be reduced by mean of secondary prevention (PAP-test, HPV-DNA test), while through primary prevention (anti-HPV vaccine) the incidence of other HPV-attributable cancers can also be reduced. In Italy, anti-HPV vaccination is part of the immunization schedule in girls since 2008, and in 2017 it was extended to boys. However, vaccine coverage is decreasing nationwide. This study aims to examine anti-HPV vaccination practices in Health care services of Lazio Region, Italy...
January 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28427470/pulmonary-hypertension-in-lymphangioleiomyomatosis-prevalence-severity-and-the-role-of-carbon-monoxide-diffusion-capacity-as-a-screening-method
#3
Carolina S G Freitas, Bruno G Baldi, Carlos Jardim, Mariana S Araujo, Juliana Barbosa Sobral, Gláucia I Heiden, Ronaldo A Kairalla, Rogério Souza, Carlos R R Carvalho
BACKGROUND: Lymphangioleiomyomatosis (LAM) is included within group 5 of the current PH classification (unclear multifactorial mechanisms). However, data regarding the occurrence of PH in LAM are scarce. The aims of the study were to describe the prevalence and characteristics of PH in a large cohort of LAM patients with different levels of severity, and to evaluate the role of echocardiography and carbon monoxide diffusion capacity (DLCO) as screening methods for PH in LAM. METHODS: One hundred five LAM patients underwent transthoracic echocardiography, pulmonary function tests (PFTs) and 6-min walk test (6MWT)...
April 20, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28426837/the-high-prevalence-of-hpv-and-hpv16-european-variants-in-cervical-and-anal-samples-of-hiv-seropositive-women-with-normal-pap-test-results
#4
Lays Paula Bondi Volpini, Neide Aparecida Tosato Boldrini, Luciana Bueno de Freitas, Angelica Espinosa Miranda, Liliana Cruz Spano
Human Immunodeficiency Virus (HIV)-seropositive women are more likely to have anogenital cancer, and high risk-HPV (HR-HPV) infection is the main associated factor. Between August 2013 and December 2015, we conducted a descriptive study to determine the HPV genotypes and HPV16 variants in cervical and anal samples of HIV-seropositive women with a normal Pap test. The viral DNA was amplified by PCR using the PGMY09/11 set of primers. Reverse line blot (RLB), restriction fragment length polymorphism (RFLP) and sequencing assays were used to determine the HPV genotypes...
2017: PloS One
https://www.readbyqxmd.com/read/28422558/understanding-transgender-men-s-experiences-with-and-preferences-for-cervical-cancer-screening-a-rapid-assessment-survey
#5
Julia Seay, Atticus Ranck, Roy Weiss, Christopher Salgado, Lydia Fein, Erin Kobetz
PURPOSE: Transgender men are less likely than cisgender women to receive cervical cancer screening. The purpose of the current study was to understand experiences with and preferences for cervical cancer screening among transgender men. METHODS: Ninety-one transgender men ages 21-63 completed the survey. The survey evaluated experiences with and preferences for screening, including opinions regarding human papillomavirus (HPV) self-sampling as a primary cervical cancer screening...
April 19, 2017: LGBT Health
https://www.readbyqxmd.com/read/28421714/endometrial-cells-on-pap-tests-ideal-reporting-is-more-complex-than-just-finding-the-right-age-ideal-reporting-of-endometrial-cells-on-pap-tests
#6
Gabor Fischer, Maha Haddad, Karen Cormier
BACKGROUND: The age for reporting normal endometrial cells (EMCs) on Pap tests was changed to ≥ 45 years in the latest Bethesda update (2014). This recommendation is solely based on age with no consensus on optimal reporting guidelines. METHODS: Pap tests with EMCs for women ≥40 years were retrieved from our Laboratory Information System (LIS). Patient age, last menstrual period (LMP) and available follow-up histology were recorded. Follow-up diagnoses were categorized as: no significant pathology, benign, hyperplasia ± atypia, or malignant...
April 19, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28415159/comparison-of-unsatisfactory-samples-from-conventional-smear-versus-liquid-based-cytology-in-uterine-cervical-cancer-screening-test
#7
Hoiseon Jeong, Sung Ran Hong, Seoung-Wan Chae, So-Young Jin, Hye Kyoung Yoon, Juhie Lee, Eun Kyung Kim, Sook Tai Ha, Sung Nam Kim, Eun-Jung Park, Jong Jae Jung, Sun Hee Sung, Sung-Chul Lim
Background: Cervical cytology for uterine cervical cancer screening has transitioned from conventional smear (CS) to liquid-based cytology (LBC), which has many advantages. The aim of this study was to compare the proportion of unsatisfactory specimens from CS versus LBC at multiple institutions including general hospitals and commercial laboratories. Materials and Methods: Each participating institution provided a minimum of 500 Papanicolaou (Pap) test results for analysis...
April 17, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28413829/prioritizing-us-cervical-cancer-prevention-with-results-from-a-geospatial-model
#8
Jonathan K Kish, Alicia I Rolin, Zhaohui Zou, James E Cucinelli, Zaria Tatalovich, Mona Saraiya, Sean F Altekruse
PURPOSE: To determine if differences in screening and vaccination patterns across the population may accentuate ethnic and geographic variation in future burden of disease. METHODS: Using Cancer in North America data provided by the North American Association of Central Cancer Registries, county cervical cancer incidence trends from 1995 to 2009 were modeled for the entire United States using ecologic covariates. Rates for health service areas were also modeled by ethnicity...
October 2016: Journal of Global Oncology
https://www.readbyqxmd.com/read/28409172/knowledge-about-cervical-cancer-and-pap-smear-and-the-factors-influencing-the-pap-test-screening-among-women
#9
Hossein Ashtarian, Elaheh Mirzabeigi, Elham Mahmoodi, Mehdi Khezeli
BACKGROUND: Although the Pap smear is known as one of the effective methods to detect the cervical cancer, a large group of women are reluctant to do the test because of various reasons. Therefore, we carried out this study to determine the level of knowledge about cervical cancer and Pap smear and the factors influencing the Pap test screening among women. METHODS: In this cross-sectional study, 355 women referred to the health centers of Gilan-e gharb city were randomly recruited in 2015...
April 2017: International Journal of Community Based Nursing and Midwifery
https://www.readbyqxmd.com/read/28397203/comparison-of-the-diagnostic-value-of-cervical-cytology-and-hpv-hr-dna-testing-for-the-diagnosis-of-low-grade-and-high-grade-squamous-intraepithelial-lesions-across-different-age-groups
#10
Aleksandra Paluszkiewicz, Dominik Pruski, Kinga Iwaniec, Witold Kędzia
OBJECTIVES: To assess the diagnostic value of cervical cytology and HPV HR DNA testing for the diagnosis of low grade and high-grade squamous intraepithelial lesions across different age groups. MATERIAL AND METHODS: The study included 1103 patients, age 25-70 years. All patients underwent in-depth diagnostic tests following either an abnormal Pap test result or a clinically suspicious cervical lesion. In all women the following examinations were performed: a molecular test detecting 14 high-risk types of HPV, a colposcopy examination, as well as directed-biopsy of the cervix...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28395701/psychometric-testing-of-the-pap-smear-belief-questionnaire-measuring-women-s-attitudes-and-beliefs-toward-cervical-cancer-screening
#11
Kelly Ackerson, Lisa Stines Doane
BACKGROUND AND PURPOSE: Some women avoid routine Pap testing because of negative attitudes and beliefs. The ability to measure these factors is limited by lack of valid and reliable tools. Therefore, this article describes steps taken to test a measure. METHODS: Validity and reliability testing of psychometric scales was conducted. RESULTS: Sample consisted of 344 women. Using principal component analysis resulted in 4 components: Exam-Related Factors, Benefits, Vulnerability, and Risks and Barriers...
April 1, 2017: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28391609/hpv-testing-in-first-void-urine-provides-sensitivity-for-cin2-detection-comparable-to-a-physician-taken-smear-or-brush-based-self-sample-cross-sectional-data-from-a-triage-population
#12
Annemiek Leeman, Marta Del Pino, Anco Molijn, Agata Rodriguez, Aureli Torné, Maurits de Koning, Jaume Ordi, Folkert van Kemenade, David Jenkins, Wim Quint
OBJECTIVES: To compare sensitivity of high-risk HPV (hrHPV) and genotype detection in self-collected morning (U1) and later (U2) urine samples, brush-based self-samples (SS) and physician-taken smears (PTS) for detecting CIN2+ in a colposcopic referral population. DESIGN: Cross-sectional single centre study. SETTING: A colposcopy clinic in Spain. POPULATION: 113 women referred for colposcopy after an abnormal Pap-smear...
April 9, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28386460/reversal-of-abnormal-cardiac-parameters-following-mitral-valve-replacement-for-severe-mitral-stenosis-in-relation-to-pulmonary-artery-pressure-a-retrospective-study-of-noninvasive-parameters-early-and-late-pattern
#13
REVIEW
Usha T Parvathy, Rajesh Rajan, Alexander Georgevich Faybushevich
BACKGROUND AND OBJECTIVES: Although the regression of pulmonary hypertension (PH) in mitral stenosis (MS) has been studied over varying periods postintervention, corresponding studies on the cardiac chamber alterations after surgery are very limited. We sought to determine the degree of reversal of these and the clinical status in connection with that of pulmonary artery pressures (PAPs) in the early and late postoperative periods. METHODS: The preoperative, early, and 1-year postoperative data - functional class (FC), cardiothoracic ratio (CTR) in chest X-ray (CXR), and echocardiographically left atrium (LA), right atrium (RA), right ventricle (RV), left ventricle (LV), and pulmonary artery (PA) dimensions, PAP, tricuspid regurgitation (TR) - of 50 patients who had mitral valve replacement (MVR) for MS with PH were retrospectively analyzed for correlations with PAP (Pearson's), and their change (t-test), in relation to that in PAP...
June 1, 2016: Interventional Medicine & Applied Science
https://www.readbyqxmd.com/read/28380627/promoting-cancer-screening-among-churchgoing-latinas-fe-en-acci%C3%A3-n-faith-in-action
#14
J P Elder, J Haughton, L G Perez, M E Martínez, C L De la Torre, D J Slymen, E M Arredondo
Cancer screening rates among Latinas are generally low, reducing the likelihood of early cancer detection in this population. This article examines the effects of a community intervention (Fe en Acción/Faith in Action) led by community health workers (promotoras) on promoting breast, cervical and colorectal cancer screening among churchgoing Latinas. Sixteen churches were randomly assigned to a cancer screening or a physical activity intervention. We examined cancer knowledge, barriers to screening and self-reported mammography, clinical breast exam, Pap test, fecal occult blood test and sigmoidoscopy or colonoscopy at baseline and 12 months follow-up...
April 1, 2017: Health Education Research
https://www.readbyqxmd.com/read/28380143/-health-behaviors-and-preventive-tests-in-adults-with-and-without-health-insurance-in-greater-metropolitan-belo-horizonte-minas-gerais-state-brazil-2003-2010
#15
Estevão Alves Valle, Juliana Vaz de Melo Mambrini, James Macinko, Maria Fernanda Lima-Costa
This study analyzed indicators for health behaviors and use of preventive services in two probabilistic samples of adults, one in 2003 (n = 13,757) and the other in 2010 (n = 12,983), with and without private health insurance in Greater Metropolitan Belo Horizonte, Minas Gerais State, Brazil. After adjusting for demographic variables, temporal variation, and source of care, there was a reduction in smoking prevalence, similar between individuals with and without private health insurance, from 2003 to 2010. During this same period the prevalence of excessive alcohol intake and sedentary lifestyle increased in both groups; with the same magnitude, there was a decrease in the prevalence of leisure-time physical activity...
April 3, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28379653/factors-related-to-prostaglandin-associated-periorbitopathy-in-glaucoma-patients
#16
Chanikarn Patradul, Visanee Tantisevi, Anita Manassakorn
PURPOSE: To determine factors related to prostaglandin-associated periorbitopathy (PAP) and its prevalence in glaucoma or ocular hypertension (OHT) patients using prostaglandins analogs (PGAs). DESIGN: A cross-sectional study. METHODS: A study of glaucoma or OHT patients, using topical PGAs for at least 3 months, was performed. Eyes treated with PGAs were photoraphed and independently evaluated for PAP by 2 glaucoma specialists using at least 4 out of 7 clinical appearances...
March 29, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28379422/surepath-specimens-versus-thinprep-specimen-types-on-the-cobas-4800-platform-high-risk-hpv-status-and-cytology-correlation-in-an-ethnically-diverse-bronx-population
#17
R C Naeem, D Y Goldstein, Mark H Einstein, G Ramos Rivera, K Schlesinger, S N Khader, M Suhrland, A S Fox
Objective: To compare the cytologic preparations of 130 cervical specimens (from women of various ethnicities at high risk for human papillomavirus [HPV] infection) using the SurePath (SP) collection system with specimens gathered using the ThinPrep (TP) system, as processed on the Cobas 4800 analyzer, to determine which collection method more accurately identifies HPV infection. Methods: In our prospective study, specimens were collected from 130 women of various ethnicities residing in or near Bronx County, NY...
March 30, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/28368950/cervical-cancer-screening-and-subsequent-procedures-in-women-under-the-age-of-25-years-between-2007-and-2013-in-france-a-nationwide-french-healthcare-database-study
#18
Géric Maura, Christophe Chaignot, Alain Weill, François Alla, Isabelle Heard
Cervical cancer screening in young women may lead to the detection of lesions with a high potential for spontaneous regression and no benefit of surgery. French guidelines recommend initiating cervical cancer screening by the Pap test from the age of 25 years. To date, no French nationwide study has assessed cervical cancer screening in young women and the related subsequent work-up and surgical procedures among screen-positive women. Using data from the French national healthcare databases (around 50 million beneficiaries), annual and 3-year Pap test screening rates were calculated among women aged 15-24 years between 2007 and 2013...
March 31, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28367183/comparison-of-linear-and-non-linear-regression-analysis-to-determine-pulmonary-pressure-in-hyperthyroidism
#19
Camelia C Scarneciu, Livia Sangeorzan, Horatiu Rus, Vlad D Scarneciu, Mihai S Varciu, Oana Andreescu, Ioan Scarneciu
OBJECTIVES: This study aimed at assessing the incidence of pulmonary hypertension (PH) at newly diagnosed hyperthyroid patients and at finding a simple model showing the complex functional relation between pulmonary hypertension in hyperthyroidism and the factors causing it. METHODS: The 53 hyperthyroid patients (H-group) were evaluated mainly by using an echocardiographical method and compared with 35 euthyroid (E-group) and 25 healthy people (C-group). In order to identify the factors causing pulmonary hypertension the statistical method of comparing the values of arithmetical means is used...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28366327/underutilization-of-the-mslt-in-sleepy-patients-with-a-short-onset-rem-period-soremp-in-the-sleep-clinic
#20
Alyssa Cairns, Richard Bogan
OBJECTIVE/BACKGROUND: A nocturnal sleep onset REM period (defined as REM onset latency ≤ 15 min; SOREMP) occurs rarely and research has shown that the phenomenon is specific for type 1 and 2 narcolepsy. However, little is known about the meaningfulness of the phenotype in general sleep clinic patients because those that exhibit the phenomenon often present with few traditional narcolepsy symptoms. As such, this study aimed to (1) evaluate the rate of eventual MSLT testing for those with a SOREMP on routine PSG when the phenomenon occurred in the absence of potential explanatory factors and (2) quantify the stability of the SOREMP phenotype...
April 2017: Sleep Medicine
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