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https://www.readbyqxmd.com/read/28226009/cervical-cancer-screening-in-teresina-piau%C3%A3-brazil-evaluation-study-using-data-of-the-cervical-cancer-information-system-2006-2013
#1
Andressa Moura Damacena, Laércio Lima Luz, Inês Echenique Mattos
OBJECTIVE: to assess the cervical cancer screening tests in Teresina, Piauí, Brazil. METHODS: this is an evaluation study of Teresina Cervical Cancer Information System (Siscolo), for the period from 2006 to 2013, based on descriptive statistical analyses. RESULTS: 604,331 pap smear tests of women residents in Teresina were registered on the system; 1.8% presented premalignant or malignant cytological conditions (atypical cells, intraepithelial lesions and cancer); positive results were higher among women aged >64 years old; there was a reduction of 43...
January 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/28225595/colorimetric-and-electrochemical-bacteria-detection-using-printed-paper-and-transparency-based-analytic-devices
#2
Jaclyn A Adkins, Katherine Boehle, Colin Friend, Briana Chamberlain, Bledar Bisha, Charles S Henry
The development of transparency-based electrochemical and paper-based colorimetric analytic detection platforms is presented as complimentary methods for food and waterborne bacteria detection from a single assay. Escherichia coli and Enterococcus species, both indicators of fecal contamination, were detected using substrates specific to enzymes produced by each species. β-galactosidase (β-gal) and β-glucosidase (β-gluco) are both produced by E. coli, while β-glucosidase (β-gluco) is produced by Enterococcus spp...
February 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28222028/expression-purification-and-characterization-of-human-cytosolic-sulfotransferase-sult-1c4
#3
Amber L Guidry, Zachary E Tibbs, Melissa Runge-Morris, Charles N Falany
Human cytosolic sulfotransferase 1C4 (hSULT1C4) is a dimeric Phase II drug-metabolizing enzyme primarily expressed in the developing fetus. SULTs facilitate the transfer of a hydrophilic sulfonate moiety from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) onto an acceptor substrate altering the substrate's biological activity and increasing the compound's water solubility. While several of the hSULTs' endogenous and xenobiotic substrates have been identified, the physiological function of hSULT1C4 remains unknown...
February 21, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28218213/surgical-treatment-of-double-outlet-right-ventricle-complicated-by-pulmonary-hypertension
#4
Qing-Yu Wu, Dong-Hai Li, Hong-Yin Li, Ming-Kui Zhang, Zhong-Hua Xu, Hui Xue
BACKGROUND: Double outlet right ventricle (DORV) is a group of complex congenital heart abnormalities. Preoperative pulmonary hypertension (PH) is considered an important risk factor for early death during the surgical treatment of DORV. The aim of this study was to report our experience on surgical treatment of DORV complicated by PH. METHODS: From June 2004 to November 2016, 61 patients (36 males and 25 females) aged 2 weeks to 26 years (median: 0.67 years and interquartile range: 0...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28214249/perceived-neighborhood-social-cohesion-and-preventive-healthcare-use
#5
Eric S Kim, Ichiro Kawachi
INTRODUCTION: Neighborhood social cohesion has been linked with better health and health behaviors, but its association with patterns of preventive healthcare use remains understudied. The hypothesis was that people with higher perceived neighborhood social cohesion would display increased use of preventive healthcare services. METHODS: Participants (N=7,168) were drawn from the 2006 wave of the Health and Retirement Study-a prospective and nationally representative panel study of American adults aged >50 years-and tracked for one wave (2 years)...
February 14, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28213603/women-s-experiences-with-cervical-cancer-screening-in-a-colposcopy-referral-clinic-in-cape-town-south-africa-a-qualitative-analysis
#6
Mariette Momberg, Matthys H Botha, Frederick H Van der Merwe, Jennifer Moodley
OBJECTIVE: The aim of this study was to explore and understand women's experience with cervical cancer screening and with the referral pathways for abnormal Papanicolau (Pap) smears. DESIGN AND SETTING: Focus group discussions were conducted with first time colposcopy clinic attendees at a tertiary hospital colposcopy clinic in Cape Town, South Africa during November 2014. A thematic analysis was conducted to identify key themes. Initial coding categories were drawn from the interview guide...
February 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28212655/elderly-onset-hereditary-pulmonary-alveolar-proteinosis-and-its-cytokine-profile
#7
Masayuki Ito, Kazuyuki Nakagome, Hiromitsu Ohta, Keiichi Akasaka, Yoshitaka Uchida, Atsushi Hashimoto, Ayako Shiono, Toshinori Takada, Makoto Nagata, Jun Tohyama, Koichi Hagiwara, Minoru Kanazawa, Koh Nakata, Ryushi Tazawa
BACKGROUND: Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by surfactant accumulation, and is caused by disruption of granulocyte/macrophage colony-stimulating factor (GM-CSF) signaling. Abnormalities in CSF2 receptor alpha (CSF2RA) were reported to cause pediatric hereditary PAP. We report here the first case of CSF2RA-mutated, elderly-onset hereditary (h) PAP. CASE PRESENTATION: The patient developed dyspnea on exertion, and was diagnosed with PAP at the age of 77 years, based on findings from chest computed tomography scan and bronchoalveolar lavage...
February 17, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28201979/wide-variation-in-sexually-transmitted-infection-testing-and-counselling-at-aboriginal-primary-health-care-centres-in-australia-analysis-of-longitudinal-continuous-quality-improvement-data
#8
Barbara Nattabi, Veronica Matthews, Jodie Bailie, Alice Rumbold, David Scrimgeour, Gill Schierhout, James Ward, Rebecca Guy, John Kaldor, Sandra C Thompson, Ross Bailie
BACKGROUND: Chlamydia, gonorrhoea and syphilis are readily treatable sexually transmitted infections (STIs) which continue to occur at high rates in Australia, particularly among Aboriginal Australians. This study aimed to: explore the extent of variation in delivery of recommended STI screening investigations and counselling within Aboriginal primary health care (PHC) centres; identify the factors associated with variation in screening practices; and determine if provision of STI testing and counselling increased with participation in continuous quality improvement (CQI)...
February 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28190541/predictors-of-adherence-to-follow-up-recommendations-after-an-abnormal-pap-smear-among-underserved-inner-city-women
#9
Suzanne M Miller, Erin K Tagai, Kuang-Yi Wen, Minsun Lee, Siu-Kuen Azor Hui, Deirdre Kurtz, John Scarpato, Enrique Hernandez
OBJECTIVES: This study aimed to identify cognitive-affective predictors of adherence to initial diagnostic colposcopy and 6-month follow-up recommendations among underserved women. METHODS: A secondary data analysis was completed of a randomized clinical trial assessing tailored telephone counseling for colposcopy adherence after an abnormal screening Pap smear among 210 underserved inner-city women. RESULTS: Adherence to initial diagnostic colposcopy was significantly associated with greater self-efficacy (OR=1...
January 31, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28182082/cytomorphometric-analysis-and-morphological-assessment-of-oral-exfoliated-cells-in-type-2-diabetes-mellitus-and-healthy-individuals-a-comparative-study
#10
Khushboo Sahay, Shweta Rehani, Priyanka Kardam, Madhumani Kumra, Rashi Sharma, Nisha Singh
CONTEXT: Oral exfoliative cytology is a simple, nonaggressive technique that is well accepted by patients. Therefore, it is an attractive option, which aids in the diagnosis and observation of epithelial atypias associated with oral mucosal diseases. AIMS: The aim of this study was to evaluate and compare the quantitative and qualitative alterations in exfoliative smears from type 2 diabetics and healthy individuals. PATIENTS AND METHODS: The study includes 30 type 2 diabetics and 30 healthy persons of both sexes...
January 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28182076/vaginal-infections-of-albanian-women-infected-with-hpv-and-their-impact-in-intraepithelial-cervical-lesions-evidenced-by-pap-test
#11
Elsa S Kone, Avenir D Balili, Piro D Paparisto, Xheladin R Ceka, Elizana D Petrela
BACKGROUND: Cervical cytology is the best single method for large screening of the population in identifying precancerous lesions of the uterine cervix. AIM: To estimate the frequency of human papillomavirus (HPV) positivity in a group of Albanian women, the prevalence of vaginal coinfections, and the relationship of coinfections with HPV, as well as their role in metaplasia or cervical intraepithelial lesions (CIN). MATERIALS AND METHODS: In this retrospective study, 2075 vaginal smears were examined...
January 2017: Journal of Cytology
https://www.readbyqxmd.com/read/28179702/knowledge-and-practices-of-nurses-on-cervical-cancer-hpv-and-hpv-vaccine-in-cankiri-state-hospital-turkey
#12
Ilknur Gol, OzUm Erkin
OBJECTIVE: To determine knowledge and practices of nurses on cervical cancer, human papillomavirus and its vaccine. METHODS: This descriptive study was conducted at Cankiri Karatekin University, Cankiri, Turkey, from December 2015 to January 2016, and included nurses. . A survey was used to collect data about socio-demographic features and knowledge and practices on cervical cancer and screening, signs and symptoms of cervical cancer and human papillomavirus vaccine...
December 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28178049/single-health-system-adherence-to-2012-cervical-cancer-screening-guidelines-at-extremes-of-age-and-posthysterectomy
#13
Deanna Teoh, Rachel Isaksson Vogel, Gretchen Hultman, Minnu Monu, Levi Downs, Melissa A Geller, Chap Le, Genevieve Melton-Meaux, Shalini Kulasingam
OBJECTIVE: To estimate the proportion of guideline nonadherent Pap tests in women aged younger than 21 years and older than 65 years and posthysterectomy in a single large health system. Secondary objectives were to describe temporal trends and patient and health care provider characteristics associated with screening in these groups. METHODS: A retrospective cross-sectional chart review was performed at Fairview Health Services and University of Minnesota Physicians...
March 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28177672/a-reappraisal-of-the-6-o-desmethylnaproxen-sulfating-activity-of-the-human-cytosolic-sulfotransferases
#14
Fatemah Alherz, Daniyah A Almarghalani, Noor A Hussein, Katsuhisa Kurogi, Ming-Cheh Liu
In this study, we aimed to obtain a comprehensive account of the human cytosolic sulfotransferases (SULTs) that are capable of sulfating 6-<i>O</i>-desmethylnaproxen (<i>O</i>-DMN), a major metabolite of naproxen. Of the 13 known human SULTs tested, seven, SULT1A1, SULT1A2, SULT1A3, SULT1B1, SULT1C2, SULT1C4, and SULT1E1, displayed <i>O</i>-DMN-sulfating activity, when analyzed using an elevated substrate concentration (500 μM) together with 14 μM of the sulfate donor, 3'-phosphoadenosine-5'-phosphosulfate (PAPS)...
January 22, 2017: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28168057/biomarkers-of-prostatic-cancer-an-attempt-to-categorize-patients-into-prostatic-carcinoma-benign-prostatic-hyperplasia-or-prostatitis-based-on-serum-prostate-specific-antigen-prostatic-acid-phosphatase-calcium-and-phosphorus
#15
Shahana Sarwar, Mohammed Abdul Majid Adil, Parveen Nyamath, Mohammed Ishaq
Prostatitis, BPH, and P.Ca are the most frequent pathologies of the prostate gland that are responsible for morbidity in men. Raised levels of PSA are seen in different pathological conditions involving the prostate. PAP levels are altered in inflammatory or infectious or abnormal growth of the prostate tissue. Serum calcium and phosphorus levels were also found to be altered in prostate cancer and BPH. The present study was carried out to study the levels of PSA, PAP, calcium, and phosphorus in serum of patients with Prostatitis, BPH, or P...
2017: Prostate Cancer
https://www.readbyqxmd.com/read/28167347/synergy-against-extensively-drug-resistant-acinetobacter-baumannii-in-vitro-by-two-old-antibiotics-colistin-and-chloramphenicol
#16
Wen-Juan Wei, Hai-Fei Yang
Combination antimicrobial therapy is an important option in the fight against Gram-negative 'superbugs'. This study systematically investigated the synergistic effect of colistin (CST) and chloramphenicol (CHL) in combination against extensively drug-resistant Acinetobacter baumannii (XDR-AB). The microtitre plate chequerboard assay was used to test synergy against 50 XDR-AB clinical strains. Then, three XDR-AB clinical isolates and the type strain A. baumannii ATCC 19606 were chosen for further synergy studies using time-kill assay, mutant prevention concentration (MPC) assay and real-time population analysis profile (PAP) assay...
February 3, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28166184/postactivation-potentiation-and-change-of-direction-speed-in-elite-academy-rugby-players
#17
Chris Bishop, Anthony N Turner, Jon Cree, Sean Maloney, James Marshall, Paul Jarvis
This study investigated the effect of preceding pro-agility sprints with maximal isometric squats to determine if postactivation potentiation (PAP) could be harnessed in change of direction speed. Sixteen elite under-17 rugby union players (age: 16 ± 0.41yrs; body mass: 88.7 ± 12.1kg, height: 1.83 ± 0.07m) from an Aviva Premiership rugby club were tested. Subjects performed a change of direction specific warm-up, followed by two baseline pro-agility tests. After 10 minutes recovery, 3 x 3-second maximal isometric squats with a 2 minute recovery between sets were completed as a conditioning activity (CA) on a force plate where peak force and mean rate of force development over 300 milliseconds were measured...
February 1, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28160449/the-significance-of-parakeratosis-alone-in-cervicovaginal-cytology-of-turkish-women
#18
Gozde Kir, Billur Cosan Sarbay, Hatice Seneldir
BACKGROUND: We aimed to analyze the significance of parakeratosis on an otherwise negative Papanicalaou (Pap) smear, in the absence of any characteristic human papilloma virus (HPV) findings. METHODS: A total of 22,076 Papanicalaou smears that were diagnosed as negative for intraepithelial lesions or malignancy between 2013 and 2015 were included in this study. Samples were separated into two groups, according to the presence of parakeratosis. We investigated the association between parakeratosis in the cytology results and a high-risk HPV status and high-grade squamous intraepithelial lesion (HSIL) in the colposcopic biopsy specimens...
February 4, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28160250/thiopurines-and-methotrexate-use-in-ibd-patients-in-a-biologic-era
#19
REVIEW
Gerassimos J Mantzaris
Although we have been living in the era of biologic therapy for several decades, the use of immunomodulators (primarily thiopurines [azathioprine and mercaptopurine] and less so methotrexate) still remains an important component of the inflammatory bowel disease (IBD) pharmaceutical arsenal. Thiopurines as monotherapy exert corticosteroid-sparing effects and can maintain long-term remission in a considerable proportion of patients who have frequent relapses and are or have become mesalazine and/or corticosteroid intolerant or refractory...
February 3, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28156562/addressing-resource-allocation-for-advance-care-planning-discussions-in-hospital
#20
(no author information available yet)
: 16 Background: Advance care planning (ACP) is fundamental in quality palliative care. There is no data detailing the demand for ACP discussions in hospitals, nor any standard objective criteria to decide urgency of such discussions. This cross-sectional study addresses this by comparing the ability of two commonly used instruments to detect palliative patients, and to predict death in the current admission. METHODS: All inpatients were censored from the largest tertiary hospital in the state on a single inpatient day...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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