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https://www.readbyqxmd.com/read/29782256/-radiofrequency-pulmonary-artery-ablation-for-treatment-of-residual-pulmonary-hypertension-after-pulmonary-endarterectomy
#1
A M CHernyavskiy, A G Edemskiy, N V Novikova, A B Romanov, S N Artemenko, B A Rudenko, A R Tarkova
OBJECTIVE: to assess the safety and efficiency of radiofrequency pulmonary artery ablation for treatment of residual pulmonary hypertension after pulmonary endarterectomy. MATERIAL AND METHODS: Radiofrequency pulmonary artery denervation (PADN) was performed in 16 patients (10 men, mean age 39 years [26; 51]). Indication for PADN was mean pulmonary artery pressure (PAP) >25 mm Hg with absence of proximal pulmonary artery lesion according to computer tomography...
April 2018: Kardiologiia
https://www.readbyqxmd.com/read/29777323/andriod-device-based-cervical-cancer-screening-for-resource-poor-settings
#2
Vidya Kudva, Keerthana Prasad, Shyamala Guruvare
Visual inspection with acetic acid (VIA) is an effective, affordable and simple test for cervical cancer screening in resource-poor settings. But considerable expertise is needed to differentiate cancerous lesions from normal lesions, which is lacking in developing countries. Many studies have attempted automation of cervical cancer detection from cervix images acquired during the VIA process. These studies used images acquired through colposcopy or cervicography. However, colposcopy is expensive and hence is not feasible as a screening tool in resource-poor settings...
May 18, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29775787/genomic-insights-of-reduced-teicoplanin-susceptible-community-acquired-methicillin-resistant-staphylococcus-aureus-mrsa-case-of-necrotizing-fasciitis
#3
Yamuna Devi Bakthavatchalam, Boopalan Ramaswamy, Rajinikanth Janakiraman, Runal John Steve, Balaji Veeraraghavan
OBJECTIVE: Glycopeptides are being increasingly used to multi-resistant MRSA infections. We report MRSA with low level teicoplanin resistance recovered from a patient treated with teicoplanin for fatal necrotizing fasciitis. PATIENT AND METHODS: MRSA recovered from a patient with necrotizing fasciitis was treated with teicoplanin. The minimum inhibitory concentration (MIC) for vancomycin and teicoplanin was determined using E-test. Reduced glycopeptide susceptibility was screened using GRD E-test and population analysis profile (PAP) method...
May 15, 2018: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29773301/pap-tests-in-the-diagnosis-of-cervical-cancer-help-or-hinder
#4
Lauren Philp, Nathaniel Jembere, Li Wang, Julia Gao, Bryan Maguire, Rachel Kupets
OBJECTIVE: To evaluate the impact of pap tests on the time to diagnosis of cervical cancer. METHODS: In this population-based retrospective cohort study, Ontario women ≥21 years diagnosed with cervical cancer between 2011 and 2014 were identified and database data collected. The presence or absence of a pap test 0-2 years preceding cancer diagnosis was identified. Descriptive and modelling analyses were performed to determine the effect of pap results on cancer diagnosis...
May 15, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29764400/low-cost-hpv-testing-and-the-prevalence-of-cervical-infection-in-asymptomatic-populations-in-guatemala
#5
Hong Lou, Eduardo Gharzouzi, Sarita Polo Guerra, Joël Fokom Domgue, Julie Sawitzke, Guillermo Villagran, Lisa Garland, Joseph F Boland, Sarah Wagner, Héctor Rosas, Jami Troxler, Heidi McMillen, Bailey Kessing, Enrique Alvirez, Miriam Castillo, Hesler Morales, Victor Argueta, Andert Rosingh, Femke J H B van Aerde-van Nunen, Griselda Lopez, Herbert M Pinedo, Mark Schiffman, Michael Dean, Roberto Orozco
BACKGROUND: A low cost and accurate method for detecting high-risk (HR) human papillomavirus (HPV) is important to permit HPV testing for cervical cancer prevention. We used a commercially available HPV method (H13, Hybribio) which was documented to function accurately in a reduced volume of cervical specimen to determine the most prevalent HPV types and the distribution of HPV infections in over 1795 cancer-free women in Guatemala undergoing primary screening for cervical cancer by cytology...
May 15, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29764329/preliminary-results-of-the-first-cervical-cancer-screening-programme-in-the-north-eastern-region-of-romania
#6
Ioana Păvăleanu, Dumitru Gafiţanu, Nicolae Ioanid, Mihaela Grigore
Objective Cervical cancer represents a major health problem in Romania. A national population-based cervical cancer screening programme was launched in 2012. The aims of the study were to assess the participation rate and to estimate the prevalence of epithelial cell abnormalities in the first four years of the programme in North Eastern Romania. Methods The participation rate, representing the proportion of eligible women screened in the programme, was evaluated for 2012-2016. The prevalence of cytological abnormalities was estimated by age group and calendar year...
January 1, 2018: Journal of Medical Screening
https://www.readbyqxmd.com/read/29762164/cervical-cancer-screening-among-hiv-infected-women-in-an-urban-u-s-safety-net-healthcare-system
#7
Arti Barnes, Andrea C Betts, Eric K Borton, Joanne M Sanders, Sandi L Pruitt, Claudia Werner, Andres Bran, Carolee D Estelle, Bijal A Balasubramanian, Stephen J Inrig, Ethan A Halm, Celette Sugg Skinner, Jasmin A Tiro
OBJECTIVE: Little is known about cervical cancer screening and results patterns among HIV infected (HIV+) women in real-world healthcare settings. We characterized two periods of screening opportunity. DESIGN: Retrospective cohort. SETTING: U.S. safety-net healthcare system in Dallas County, Texas. SUBJECTS: We analyzed data from electronic medical records (EMR) of 1,490 HIV+ women receiving care 2010-2014. MAIN OUTCOME MEASURES: At baseline, we categorized a woman's Pap status 15 months prior to index date as under-screened (vs...
May 11, 2018: AIDS
https://www.readbyqxmd.com/read/29746625/extended-human-papillomavirus-genotype-distribution-and-cervical-cytology-results-in-a-large-cohort-of-chinese-women-with-invasive-cervical-cancers-and-high-grade-squamous-intraepithelial-lesions
#8
Wei Jiang, R Marshall Austin, Lei Li, Kaixuan Yang, Chengquan Zhao
Objectives: To study the human papillomavirus (HPV) genotype distribution of cervical cancer (CxCa) and cervical intraepithelial neoplasia grade 2/3 (CIN2/3) in China and to evaluate cotesting of HPV and cytology in CxCa screening. Methods: Patients with histopathologic CxCa and CIN 2/3 diagnoses reported between January 2012 and June 2016 and extended HPV genotype testing in the prior 6 months were documented in the institute. Available prior Papanicolaou (Pap) test results were also documented...
April 16, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29745561/-image-segmentation-and-classification-of-cytological-cells-based-on-multi-features-clustering-and-chain-splitting-model
#9
Pin Wang, Qianqian Liu, Lirui Wang, Yongming Li, Shujun Liu, Fang Yan
The diagnosis of pancreatic cancer is very important. The main method of diagnosis is based on pathological analysis of microscopic image of Pap smear slide. The accurate segmentation and classification of images are two important phases of the analysis. In this paper, we proposed a new automatic segmentation and classification method for microscopic images of pancreas. For the segmentation phase, firstly multi-features Mean-shift clustering algorithm (MFMS) was applied to localize regions of nuclei. Then, chain splitting model (CSM) containing flexible mathematical morphology and curvature scale space corner detection method was applied to split overlapped cells for better accuracy and robustness...
August 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29735381/escherichia-coli-isolates-from-patients-with-inflammatory-bowel-disease-expec-virulence-and-colicin-determinants-are-more-frequent-compared-to-healthy-controls
#10
Lenka Micenková, Lucia Frankovičová, Iva Jaborníková, Juraj Bosák, Petr Dítě, Jan Šmarda, Martin Vrba, Alena Ševčíková, Marta Kmeťová, David Šmajs
A set of 178 Escherichia coli isolates taken from patients with inflammatory bowel disease (IBD) was analyzed for bacteriocin production and tested for the prevalence of 30 bacteriocin and 22 virulence factor determinants. Additionally, E. coli phylogenetic groups were also determined. Pulsed-field gel electrophoresis (PFGE) was used for exclusion of clonal character of isolates. Results were compared to data from a previously published analysis of 1283 fecal commensal E. coli isolates. The frequency of bacteriocinogenic isolates (66...
May 1, 2018: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/29734247/clinical-and-economic-value-of-p16ink4a-for-the-differential-diagnosis-of-morphologic-cervical-intraepithelial-neoplasia-2
#11
Vanina S Fishkel, Fernando C Monge, Felicitas M von Petery, Karen E Tapper, Teresa M Peña, Florencia Torres, Fernando A Poletta, Jorge F Elgart, Alejandra Avagnina, Valeria Denninghoff
The detection of high-grade intraepithelial lesions requires highly sensitive and specific methods that allow more accurate diagnoses. This contributes to a proper management of preneoplastic lesions, thus avoiding overtreatment. The purpose of this study was to analyze the value of immunostaining for p16 in the morphologic assessment of cervical intraepithelial neoplasia 2 lesions, to help differentiate between low-grade (p16-negative) and high-grade (p16-positive) squamous intraepithelial lesions. The direct medical cost of the treatment of cervical intraepithelial neoplasia 2 morphologic lesions was estimated...
May 4, 2018: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/29733302/excess-cost-of-cervical-cancer-screening-beyond-recommended-screening-ages-or-after-hysterectomy-in-a-single-institution
#12
Deanna Teoh, Gretchen Hultman, McKenzie DeKam, Rachel Isaksson Vogel, Levi S Downs, Melissa A Geller, Chap Le, Genevieve Melton, Shalini Kulasingam
OBJECTIVE: The aim of the study was to estimate the excess cost of guideline nonadherent cervical cancer screening in women beyond the recommended screening ages or posthysterectomy in a single healthcare system. MATERIALS AND METHODS: All Pap tests performed between September 1, 2012, and August 31, 2014, in women younger than 21 years, older than 65 years, or after hysterectomy, were coded as guideline adherent or nonadherent per the 2012 America Society of Colposcopy and Clinical Pathology guidelines...
May 3, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29729092/improved-removal-of-blood-contamination-from-thinprep-cervical-cytology-samples-for-raman-spectroscopic-analysis
#13
Damien Traynor, Shiyamala Duraipandian, Cara M Martin, John J O'Leary, Fiona M Lyng
There is an unmet need for methods to help in the early detection of cervical precancer. Optical spectroscopy-based techniques, such as Raman spectroscopy, have shown great potential for diagnosis of different cancers, including cervical cancer. However, relatively few studies have been carried out on liquid-based cytology (LBC) pap test specimens and confounding factors, such as blood contamination, have been identified. Previous work reported a method to remove blood contamination before Raman spectroscopy by pretreatment of the slides with hydrogen peroxide...
May 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29728104/disparities-in-cervical-screening-participation-a-comparison-of-russian-somali-and-kurdish-immigrants-with-the-general-finnish-population
#14
Esther E Idehen, Päivikki Koponen, Tommi Härkänen, Mari Kangasniemi, Anna-Maija Pietilä, Tellervo Korhonen
BACKGROUND: Cervical cancer is currently ranked as the fourth commonly diagnosed cancer in women globally. A higher incidence has been reported in low- and-middle-income countries, and the disease poses significant public health challenges. Evidence suggests that this disease is preventable by means of regular screening using the Papanicolaou (Pap) test. However, limited knowledge exists about disparities in cervical screening participation among immigrants compared with non-immigrants, in countries with universal cervical screening programmes...
May 4, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29727786/the-association-between-cervical-inflammation-and-histologic-evidence-of-hpv-in-pap-smears-and-adverse-pregnancy-outcome-in-low-risk-population
#15
Maya Nimrodi, Vered Kleitman, Tamar Wainstock, Ofer Gemer, Michai Meirovitz, Eli Maymon, Neta Benshalom-Tirosh, Offer Erez
OBJECTIVE: Recent studies suggest an association between Human Papilloma Virus (HPV) infection, cervical inflammation and obstetric complications (i.e. spontaneous preterm parturition and cervical insufficiency). It has been proposed that viral inflammation of the placenta causes changes in the mother's immune reaction to bacterial pathogens, which leads to enhanced inflammatory reaction and preterm delivery. Therefore, the aim of this population-based study was to determine the association between abnormal cervical cytology prior to pregnancy and obstetric outcomes...
April 20, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29725409/malignant-lymphoma-of-the-uterine-cervix-presumptively-diagnosed-by-pap-smear-a-case-report
#16
Takahiro Koyanagi, Haruhiko Kondo, Atsushi Toyama, Miho Ando, Sakiko Imaoka, Masayo Inamura, Hiroko Yamamoto, Sumie Nakamura, Yoko To, Tatsuya Fukami, Maki Goto, Hiroshi Tsujioka, Fuyuki Eguchi
Malignant lymphoma of the uterine cervix is exceedingly rare and is difficult to diagnose by cervical cytology. The current study presents a case of malignant lymphoma of the uterine cervix that was presumptively diagnosed by cervical cancer screening in which the patient had no clinical symptoms. The anterior lip of the uterine cervix was occupied by a macroscopic hemorrhagic tumor. The obtained tumor cells exhibited typical cytological features of malignant lymphoma and were positive for CD20. The final diagnosis was diffuse large B cell lymphoma of the uterine cervix, stage IIEA (Ann Arbor classification)...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29722175/lack-of-transformation-zone-in-cervical-pap-tests-should-it-be-a-concern-a-quality-assurance-initiative
#17
Evelyn Carolina Polanco Jacome, Jennifer Maerki, Karen Chau, Meredith Akerman, Sujata Sajjan, Melissa Klein, Cecilia Gimenez, Alice Laser, Kasturi Das
BACKGROUND: Bethesda guidelines do not require presence of transformation zone (TZ) for a cervical Pap test to be deemed adequate. However, clinicians are concerned with specimens that are reported to lack TZ. METHODS: We analyzed 566 ThinPrep cases reported as negative for intraepithelial lesion or malignancy (NILM) with no cervical abnormality detected in previous 4 years (2007-2011). These cases were divided into two cohorts; those with TZ (ETZ) and those without TZ (NTZ)...
May 2, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29717924/prevalence-and-burden-related-to-genital-warts-in-india
#18
Uday S Khopkar, Murlidhar Rajagopalan, Anahita R Chauhan, Smita Kothari-Talwar, Puneet K Singhal, Karen Yee, Amit Kulkarni, Nuria Lara, Montserrat Roset, Anna R Giuliano, Suzanne M Garland
The prevalence of genital warts (GW) and self-reported human papillomavirus (HPV) as well as disease-related psychosocial impact among male and female patients aged 18-60 years in India were assessed. GW prevalence was estimated using a 2-week daily log of patients examined from June 7-September 22, 2011 by 200 participating physicians in 6 regions of India. Psychosocial impact was estimated using one-time, self-administered surveys, including HPV Impact Profile (HIP), Cuestionario Específico para Condiloma Acuminado ([Spanish] CECA; "Specific questionnaire for Condylomata Acuminata") and EuroQol-5 Dimension survey...
May 2, 2018: Viral Immunology
https://www.readbyqxmd.com/read/29708835/the-effect-of-history-of-abnormal-pap-smear-or-preceding-hpv-infection-on-the-humoral-immune-response-to-quadrivalent-human-papilloma-virus-qhpv-vaccine-in-women-with-systemic-lupus-erythematosus
#19
J Patricia Dhar, Lynnette Essenmacher, Renee Dhar, Ardella Magee, Joel Ager, Robert J Sokol
OBJECTIVE: To determine if natural human papillomavirus (HPV) infection would induce an anamnestic response to quadrivalent (qHPV) vaccine in women with Systemic Lupus Erythematosus (SLE). METHODS: Thirty four women (19-50 years) with mild to moderate and minimally active or inactive SLE received standard qHPV vaccine. Neutralizing antibody titers to HPV 6, 11, 16 and18 were evaluated pre- and post- vaccine using HPV competitive Luminex Immunoassay. For each HPV type, logistic regressions were performed to explore the relationship between a positive titer at baseline with their final geometric mean titer and with the rise in titer...
April 30, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29706716/the-relationship-between-physical-fitness-and-academic-achievement-among-adolescent-in-south-korea
#20
Gun-Soo Han
[Purpose] The purpose of this study was to identify the relationship between physical fitness level and academic achievement in middle school students. [Subjects and Methods] A total of 236 students aged 13-15 from three middle schools in D city, South Korea, were selected using a random sampling method. Academic achievement was measured by students' 2014 fall-semester final exam scores and the level of physical fitness was determined according to the PAPS (Physical Activity Promotion System) score administrated by the Korean Ministry of Education...
April 2018: Journal of Physical Therapy Science
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