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Epicardial adipose tissue measurement

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https://www.readbyqxmd.com/read/28160962/increased-serum-renalase-in-peritoneal-dialysis-patients-is-it-related-to-cardiovascular-disease-risk
#1
Ebru Gok Oguz, Hadim Akoglu, Gulay Ulusal Okyay, Guner Karaveli Gursoy, Tolga Yildirim, Ozgur Merhametsiz, Tolga Cimen, Basol Canbakan, Ekrem Yeter, M Deniz Ayli
BACKGROUND: Renalase, with possible monoamine oxidase activity, is implicated in degradation of catecholamines; which suggests novel mechanisms of cardiovascular complications in patients with chronic kidney diseases. Epicardial adipose tissue (EAT) has been found to correlate with cardiovascular diseases (CVD) in dialysis patients. The present study aimed to evaluate the association of serum renalase levels with EAT thickness and other CVD risk factors in peritoneal dialysis (PD) patients...
February 1, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28144263/neutrophil-to-lymphocyte-ratio-as-a-possible-indicator-of-epicardial-adipose-tissue-in-patients-undergoing-hemodialysis
#2
Adalet Ozcicek, Fatih Ozcicek, Gursel Yildiz, Aysu Timuroglu, Levent Demirtas, Mutlu Buyuklu, Ufuk Kuyrukluyildiz, Emin Murat Akbas, Ergun Topal, Kultigin Turkmen
INTRODUCTION: Chronic inflammation is a major risk factor in the pathogenesis of cardiovascular disease in end-stage renal disease (ESRD) patients. Epicardial adipose tissue (EAT) is the true visceral fat depot of the heart. The relationship between coronary artery disease and EAT was shown in healthy subjects and ESRD patients. In the present study we aimed to investigate the relationship between EAT and inflammation parameters including neutrophil-to-lymphocyte ratio (NLR) in hemodialysis (HD) patients...
February 1, 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28137715/postmenopausal-women-with-greater-paracardial-fat-have-more-coronary-artery-calcification-than-premenopausal-women-the-study-of-women-s-health-across-the-nation-swan-cardiovascular-fat-ancillary-study
#3
Samar R El Khoudary, Kelly J Shields, Imke Janssen, Matthew J Budoff, Susan A Everson-Rose, Lynda H Powell, Karen A Matthews
BACKGROUND: Volumes of paracardial adipose tissue (PAT) and epicardial adipose tissue (EAT) are greater after menopause. Interestingly, PAT but not EAT is associated with estradiol decline, suggesting a potential role of menopause in PAT accumulation. We assessed whether volumes of heart fat depot (EAT and PAT) were associated with coronary artery calcification (CAC) in women at midlife and whether these associations were modified by menopausal status and estradiol levels. METHODS AND RESULTS: EAT and PAT volumes and CAC were measured using electron beam computed tomography scans...
January 29, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28124506/liraglutide-causes-large-and-rapid-epicardial-fat-reduction
#4
Gianluca Iacobellis, Mahshid Mohseni, Suzy D Bianco, Pritisheel K Banga
OBJECTIVE: Epicardial adipose tissue (EAT), the visceral fat depot of the heart, is a modifiable cardiovascular risk factor and emerging therapeutic target. Liraglutide, an analog of glucagon-like peptide-1, is indicated for the treatment of type 2 diabetes mellitus. Liraglutide has recently been shown to reduce cardiovascular risk. Nevertheless, whether liraglutide could reduce EAT is unknown. METHODS: To test the hypothesis, a 6-month randomized, open-label, controlled study was performed in 95 type 2 diabetic subjects with body mass index (BMI) ≥27 kg/m(2) and hemoglobinA1c ≤8% on metformin monotherapy...
February 2017: Obesity
https://www.readbyqxmd.com/read/28115810/epicardial-adiposity-is-associated-with-microalbuminuria-in-patients-with-essential-hypertension
#5
Mujgan Tek Ozturk, Fatma Ayerden Ebinç, Gülay Ulusal Okyay, Aysun Akbal Kutlugün
BACKGROUND: Measurement of epicardial adipose tissue (EAT) is suggested as a novel cardiometabolic risk factor. Microalbuminuria is a marker of endothelial dysfunction and is associated with an increased risk for cardiovascular disease in patients with systemic hypertension. The aim of this study was to investigate the relationship of echocardiographic epicardial adipose tissue (EAT) thickness and microalbuminuria in hypertensive patients. METHODS: 75 essential hypertensive patients were included into the study...
January 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/28007022/impact-of-obesity-and-epicardial-fat-on-early-left-atrial-dysfunction-assessed-by-cardiac-mri-strain-analysis
#6
Morgane Evin, Kathryn M Broadhouse, Fraser M Callaghan, Rachel T McGrath, Sarah Glastras, Rebecca Kozor, Samantha L Hocking, Jérôme Lamy, Alban Redheuil, Nadjia Kachenoura, Greg R Fulcher, Gemma A Figtree, Stuart M Grieve
BACKGROUND: Diastolic dysfunction is a major cause of morbidity in obese individuals. We aimed to assess the ability of magnetic resonance imaging (MRI) derived left atrial (LA) strain to detect early diastolic dysfunction in individuals with obesity and type 2 diabetes, and to explore the association between cardiac adipose tissue and LA function. METHODS: Twenty patients with obesity and T2D (55 ± 8 years) and nineteen healthy controls (48 ± 13 years) were imaged using cine steady state free precession and 2-point Dixon cardiovascular magnetic resonance...
22, 2016: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/27999858/frailty-syndrome-visceral-adipose-tissue-and-frailty-in-patients-with-symptomatic-severe-aortic-stenosis
#7
M Pinheiro, J Mancio, G Conceição, W Ferreira, M Carvalho, A Santos, L Vouga, V Gama Ribeiro, A Leite-Moreira, I Falcão-Pires, N Bettencourt
BACKGROUND/OBJECTIVES: In patients with severe aortic stenosis (AS), frailty is a clinically relevant measure of increased vulnerability that should be included in the preoperative risk assessment. Bioelectrical impedance analysis (BIA) derived phase angle (PA) reflects cell membrane integrity and function. Few studies are available on the relative contribution of adiposity distribution on frailty, and about the influences of frailty and visceral obesity in PA value. Therefore, we aimed to evaluate associations among frailty, visceral fat depots and PA in patients with symptomatic severe AS...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/27988072/epicardial-adipose-tissue-is-related-to-cardiac-function-in-elderly-women-but-not-in-men
#8
Su-A Kim, Mi-Na Kim, Wan-Joo Shim, Seong-Mi Park
BACKGROUND AND AIM: Epicardial adipose tissue (EAT) is easily quantifiable visceral adipose tissue that is closely associated with cardiometabolic disease including heart failure with preserved left ventricular (LV) ejection fraction. As body fat distribution and metabolism are different between men and women, we evaluated the sex difference in EAT thickness and its relationship to cardiac function. METHODS AND RESULTS: A total of 152 consecutive patients (76 men) with mean age of 62 ± 9 years were enrolled...
January 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/27958614/the-relationship-between-location-specific-epicardial-adipose-tissue-volume-and-coronary-atherosclerotic-plaque-burden-in-type-2-diabetic-patients
#9
Begum Uygur, Omer Celik, Derya Ozturk, Mehmet Erturk, Hafize Otcu, Fethi Emre Ustabasıoglu, Aydın Yıldırım
BACKGROUND AND AIM: Epicardial adipose tissue is a metabolically active visceral fat depot which plays an important role in the pathogenesis of coronary atherosclerosis. Due to its asymmetrical distribution, the relation between location-specific epicardial adipose tissue measurements and coronary atherosclerosis remains unclear. Our study investigated the relationship between location-specific epicardial adipose tissue volume and coronary atherosclerotic plaque burden which was detected by coronary computed tomography angiography in Type 2 diabetic patients without coronary artery disease history...
December 13, 2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27931089/prognostic-implications-of-epicardial-fat-volume-quantification-in-acute-pericarditis
#10
George Lazaros, Alexios S Antonopoulos, Evangelos K Oikonomou, Panagiotis Vasileiou, Evangelos Oikonomou, Evangelia Stroumpouli, Apostolos Karavidas, Charalambos Antoniades, Dimitris Tousoulis
BACKGROUND: The pathophysiology of acute pericarditis remains largely unknown, and biomarkers are needed to identify patients susceptible to complications. As adipose tissue has a pivotal role in cardiovascular disease pathogenesis, we hypothesized that quantification of epicardial fat volume (EFV) provides prognostic information in patients with acute pericarditis. MATERIALS AND METHODS: Fifty (n = 50) patients with first diagnosis of acute pericarditis were enrolled in this study...
December 8, 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27923804/associations-of-epicardial-abdominal-and-overall-adiposity-with-atrial-fibrillation
#11
Christopher X Wong, Michelle T Sun, Ayodele Odutayo, Connor A Emdin, Rajiv Mahajan, Dennis H Lau, Rajeev K Pathak, Dennis T Wong, Joseph B Selvanayagam, Prashanthan Sanders, Robert Clarke
BACKGROUND: Although adiposity is increasingly recognized as a risk factor for atrial fibrillation (AF), the importance of epicardial fat compared with other adipose tissue depots remains uncertain. We sought to characterize and compare the associations of AF with epicardial fat and measures of abdominal and overall adiposity. METHODS AND RESULTS: We conducted a meta-analysis of 63 observational studies including 352 275 individuals, comparing AF risk for 1-SD increases in epicardial fat, waist circumference, waist/hip ratio, and body mass index...
December 2016: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/27919360/association-of-epicardial-fat-volume-and-nonalcoholic-fatty-liver-disease-with-metabolic-syndrome-from-the-caesar-study
#12
Byung Jin Kim, Hak Soo Kim, Jung Gyu Kang, Bum Soo Kim, Jin Ho Kang
BACKGROUND AND AIMS: Epicardial adipose tissue or nonalcoholic fatty liver disease (NAFLD) can be one of putative risk factors for metabolic syndrome (MetS). However, there are no data assessing the associations of MetS with epicardial fat and NAFLD. The present study was performed to evaluate the combined effect of epicardial fat volume (EFV) and NAFLD on MetS in Korean adults. METHODS AND RESULTS: Computed tomographic EFV and ultrasonographic fatty liver were measured in 1472 individuals (1242 men: mean age, 44 ± 8...
November 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/27919158/maximal-pericoronary-adipose-tissue-thickness-is-associated-with-hypertension-in-nonobese-patients-with-acute-or-chronic-illness
#13
Shinhae Chang, Wangjin Lee, Byounggyu Kwag, Yun Hee Chung, In Sook Kang
Background/Aims: Recent studies have shown an association of epicardial fat thickness with diabetes and hypertension (HTN) in asymptomatic populations. However, there is lack of information as to whether there is similar association between pericoronary adipose tissue (PAT) and HTN in the patients who have acute or chronic illness. Methods: This study included 214 nonobese patients hospitalized with acute or chronic noncardiogenic illness. PAT thicknesses were measured from fat tissues surrounding left and right coronary arteries in enhanced, chest computed tomography scans, yielding the maximal PAT value from left and right coronary arteries was used for analysis...
December 6, 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27910111/cystatin-c-and-epicardial-adipose-tissue-as-noninvasive-predictors-of-cardiovascular-risk-in-acromegaly
#14
Anna Aulinas, Iris Crespo, David Viladés, Ruben Leta, Eulàlia Urgell, Betina Biagetti, Susan M Webb, Elena Valassi
BACKGROUND: Acromegaly (ACRO) is associated with elevated cardiovascular risk, although the prevalence of coronary artery disease (CAD) is unclear. Increased epicardial adipose tissue (EAT) and elevated cystatin-C (Cys-C) levels are cardiovascular risk factors, also related to the progression of CAD in several populations. AIMS: To measure the severity and extent of CAD in patients with ACRO and to determine whether either EAT or Cys-C reflect higher cardiovascular risk in patients with ACRO than in healthy controls...
February 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/27899941/influence-of-increased-epicardial-adipose-tissue-volume-on-1-year-in-stent-restenosis-in-patients-who-received-coronary-stent-implantation
#15
Ying Zhou, Hua-Wei Zhang, Feng Tian, Jin-Song Chen, Tian-Wen Han, Ya-Hang Tan, Jia Zhou, Tao Zhang, Jing Jing, Yun-Dai Chen
BACKGROUND: Epicardial adipose tissue (EAT) is significantly associated with the formation and composition of coronary atherosclerotic plaque, cardiac events and the clinical prognosis of coronary heart disease. But, whether increased EAT deposition may affect the incidence of in-stent restenosis (ISR) is currently unclear. This study used coronary computed tomography angiography (CCTA) as a mean to investigate whether increased EAT volume was associated with ISR. METHODS: A total of 364 patients who underwent 64-slice CCTA examination for the evaluation of suspected coronary artery disease, and subsequently underwent percutaneous coronary intervention (PCI) for the first time, and then accepted coronary angiography (CA) follow-up for ISR examination in one year, were retrospectively included in this study...
September 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27888013/epicardial-adipose-tissue-in-the-general-middle-aged-population-and-its-association-with-metabolic-syndrome
#16
Álvaro Calabuig, Joaquín Barba, María Jesús Guembe, Javier Díez, Jesús Berjón, Eduardo Martínez-Vila, Pablo Irimia, Estefanía Toledo
INTRODUCTION AND OBJECTIVES: There is currently increasing interest in epicardial adipose tissue (EAT) as a marker of cardiovascular disease. Our purpose was to describe EAT, measured by transthoracic echocardiography, and to assess its association with metabolic syndrome (MS) in the RIVANA population-based study. METHODS: Physical examination was performed in 880 participants aged 45 to 74 years (492 of them with MS according to the harmonized definition). Fasting glucose, high-density lipoprotein cholesterol, triglyceride, and C-reactive protein concentrations were determined in a blood sample...
November 22, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27878751/assessment-of-the-relationship-between-serum-paraoxonase-activity-and-epicardial-adipose-tissue-in-hemodialysis-patients
#17
Emad Abdallah, Samya El-Shishtawy, Nevine Sherif, Ahmed Ali, Omnia El-Bendary
PURPOSE: Paraoxonase-1 (PON-1) is a high-density lipoprotein-associated (HDL) enzyme, which has been shown to reduce susceptibility to low-density lipoprotein (LDL) peroxidation. Epicardial adipose tissue (EAT) is a marker of atherosclerosis. The aim of this study was to determine the relationship between PON-1 activity and EAT in hemodialysis (HD) patients. METHODS: This is a cross-sectional study conducted on 72 (43 males) HD patients with end-stage renal disease...
November 23, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27875723/orosomucoid-as-prognosis-factor-associated-with-inflammation-in-acute-or-nutritional-status-in-chronic-heart-failure
#18
Rosa M Agra, Alfonso Varela-Román, Rocío González-Ferreiro, Juan E Viñuela, Ana Castro-Pais, Ángel Fernández-Trasancos, Esther Díaz-Rodríguez, Ezequiel Álvarez, Marcos C Carreira, Felipe F Casanueva, José R González-Juanatey, Sonia Eiras
BACKGROUND: Inflammation and nutritional state are involved in the pathogenesis of heart failure (HF). OBJECTIVE: To study the contribution of alpha-1-acid-glycoprotein (AGP) to these factors and its prognostic value in acute (AHF) or chronic HF (CHF). METHODS: The observational study has included 147 patients (mean age 70years, 62% men) admitted to a cardiology department for HF and followed-up for an average 326.6±140.8days. Blood AGP values were measured by Enzyme-Linked ImmunoSorbent Assay...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27871080/the-association-between-premature-adrenarche-and-cardiovascular-risk-may-be-greater-than-expected
#19
Nurullah Çelik, Hayrullah Alp, Emine Çamtosun, Esma Alp, Sibel Çelik, Erhan Berk
AIM: The aim of this study was to investigate the cardiovascular risk of children with premature adrenarche (PA). METHODS: A total of 75 children (44 with PA and 31 control subjects) aged 6-10 years were included in the study. Their metabolic, anthropometric, and echocardiographic parameters were recorded and compared. RESULTS: Triglyceride, DHEA-SO4, and 17-hydroxyprogesterone levels were significantly higher in the PA group (p = 0.04, p = 0...
November 22, 2016: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/27864479/epicardial-adipose-tissue-and-cardiovascular-outcome-in-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention
#20
Maximilian Tscharre, Christina Hauser, Miklos Rohla, Matthias K Freynhofer, Johann Wojta, Kurt Huber, Thomas W Weiss
AIMS: We investigated the association between epicardial adipose tissue (EAT) thickness and cardiovascular outcomes in a cohort of high-risk patients with acute coronary syndrome undergoing percutaneous coronary intervention. METHODS: Of 1198 patients undergoing percutaneous coronary intervention, transthoracic echocardiography was performed in 438 patients during the index hospitalization. EAT thickness was measured in the parasternal long-axis view perpendicularly on the free wall of the right ventricle at end-systole in three consecutive cardiac cycles and then averaged...
November 18, 2016: European Heart Journal. Acute Cardiovascular Care
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