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Epicardial adipose tissue measurement

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https://www.readbyqxmd.com/read/29776809/the-presence-of-fragmented-qrs-is-associated-with-increased-epicardial-adipose-tissue-and-subclinical-myocardial-dysfunction-in-healthy-individuals
#1
Mehmet Yaman, Ugur Arslan, Adil Bayramoglu, Osman Bektas, Zeki Yuksel Gunaydin, Ahmet Kaya
AIM: The aim of this study was to measure epicardial adipose tissue (EAT) and to assess left ventricular (LV) systolic and diastolic function in a healthy population grouped according to the presence of fragmented QRS (fQRS). METHODS: In this prospective case-control study, the study population consisted of 308 healthy individuals who were divided into two groups according to the existence of fQRS: 180 fQRS(+) individuals (with fQRS), and 128 age- and gender-matched fQRS(-) individuals (without fQRS)...
May 15, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29764718/metabolic-syndrome-associates-with-left-atrial-dysfunction
#2
K Nyman, M Granér, M O Pentikäinen, J Lundbom, A Hakkarainen, R Sirén, M S Nieminen, M-R Taskinen, N Lundbom, K Lauerma
BACKGROUND AND AIMS: Obesity and metabolic syndrome (MetS) are risk factors of atrial fibrillation (AF), but limited data exist on their effect on left atrial (LA) function. The aim of the study was to evaluate the effects of cardiac, hepatic and intra-abdominal ectopic fat depots and cardiometabolic risk factors on LA function in non-diabetic male subjects. METHODS AND RESULTS: Myocardial and hepatic triglyceride contents were measured with 1.5T 1 H-magnetic resonance spectroscopy and LA and left ventricular function, visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), epicardial and pericardial fat by magnetic resonance imaging (MRI) in 33 men with MetS and 40 men without MetS...
February 21, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29757253/association-of-cardiovascular-health-with-epicardial-adipose-tissue-and-intima-media-thickness-the-kardiovize-study
#3
Jana Hruskova, Andrea Maugeri, Helena Podroužková, Tatiana Štípalová, Juraj Jakubík, Martina Barchitta, Jose R Medina-Inojosa, Martin Homolka, Antonella Agodi, Sarka Kunzova, Ondrej Sochor, Francisco Lopez-Jimenez, Manlio Vinciguerra
Background: Intima-media thickness (IMT) has been proposed as a measurement of subclinical atherosclerosis and has been associated with cardiovascular disease (CVD). Epicardial adipose tissue (EAT) is a fat depot between the pericardium and myocardium and has been associated with coronary atherosclerosis. The relationship between IMT and EAT thickness has not been reported before. We investigated the relationship between EAT thickness, IMT, CVD risk factors, and ideal cardiovascular health (CVH) metrics using subjects from the Kardiovize Brno 2030 cohort study, a random urban sample population in Central Europe...
May 13, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29750183/serum-adiponectin-and-tnf%C3%AE-concentrations-are-closely-associated-with-epicardial-adipose-tissue-fatty-acid-profiles-in-patients-undergoing-cardiovascular-surgery
#4
Tatsuya Sawaguchi, Toshiaki Nakajima, Takaaki Hasegawa, Ikuko Shibasaki, Hiroyuki Kaneda, Syotaro Obi, Toshiyuki Kuwata, Masashi Sakuma, Shigeru Toyoda, Mitsuo Ohni, Shichiro Abe, Hirotsugu Fukuda, Teruo Inoue
Background: Epicardial adipose tissue (EAT) releases both adiponectin and TNFα, and these two adipokines play important roles in heart diseases such as coronary arterial disease. The aim of the present study was to clarify whether fatty acid (FA) profiles in EAT are linked to the serum concentration of these adipokines. The relationships between serum adipokine levels and FA profiles in patients undergoing cardiovascular surgery were analyzed. Methods: Patients ( n  = 21) undergoing cardiovascular surgery (11 males, 70...
March 2018: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/29723863/epicardial-fat-thickness-in-patients-with-autosomal-dominant-polycystic-kidney-disease
#5
Antonio Concistrè, Luigi Petramala, Gianmarco Scoccia, Susanna Sciomer, Valeria Bisogni, Vincenza Saracino, Gino Iannucci, Silvia Lai, Daniela Mastroluca, Gianluca Iacobellis, Claudio Letizia
INTRODUCTION: Autosomal dominant polycystic kidney disease (ADPKD) is associated with early organ damage such as left ventricular hypertrophy and higher cardiovascular risk when compared to essential hypertension (EH). Epicardial adipose tissue (EAT) is a new cardiovascular risk factor, but its role and correlation with left ventricular mass (LVM) in ADPKD is unknown. AIMS: we sought to investigate whether EAT is higher and related to LVM indexed by body surface area (LVMi) in hypertensive patients with ADPKD compared to those with EH...
May 3, 2018: Cardiorenal Medicine
https://www.readbyqxmd.com/read/29721664/echocardiographic-measurements-of-epicardial-adipose-tissue-and-comparative-ability-to-predict-adverse-cardiovascular-outcomes-in-patients-with-coronary-artery-disease
#6
Julieta D Morales-Portano, Juan Ángel Peraza-Zaldivar, Juan A Suárez-Cuenca, Rocío Aceves-Millán, Lilia Amezcua-Gómez, Carlos H Ixcamparij-Rosales, Rafael Trujillo-Cortés, Rogelio Robledo-Nolasco, Paul Mondragón-Terán, Rebeca Pérez-Cabeza de Vaca, Rolando Hernández-Muñoz, Alberto Melchor-López, Mani A Vannan, Alberto Francisco Rubio-Guerra
The present study aimed to compare echocardiography measurements of epicardial adipose tissue (EAT) thickness and other risk factors regarding their ability to predict adverse cardiovascular outcomes in patients with coronary artery disease (CAD). Outcomes of 107 patients (86 males, 21 females, mean age 63.6 years old) submitted to diagnostic echocardiography and coronary angiography were prospectively analyzed. EAT (measures over the right ventricle, interventricular groove and complete bulk of EAT) and left ventricle ejection fraction (LVEF) were performed by echocardiography...
May 2, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29688734/assessing-the-relation-of-epicardial-fat-thickness-and-volume-quantified-by-256-slice-computed-tomography-scan-with-coronary-artery-disease-and-cardiovascular-risk-factors
#7
Maryam Mohammadzadeh, Vahid Mohammadzadeh, Madjid Shakiba, Marzieh Motevalli, Azadeh Abedini, Sakineh Kadivar, Pouya Entezari, Ali Mohammadzadeh
BACKGROUND: This study aimed to investigate the association between epicardial adipose tissue (EAT) and coronary artery disease (CAD) as well as cardiovascular risk factors. METHODS: Complete medical records of subjects were reviewed and cardiovascular risk factors were recorded. Epicardial fat volume (EFV) and epicardial fat thickness (EFT) were measured using digital volumetry of acquired images using a 256-slice CT-scanner. Calcium score was measured using Agatston method in non-contrast images...
March 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29650237/relation-between-wrist-circumference-and-left-ventricular-structure-in-overweight-children
#8
Simona Zampetti, Giuseppe Campagna, Gaetano Leto, Federica Lucantoni, Luca D'Onofrio, Lidia Marandola, Chiara Moretti, Claudio Chiesa, Lucia Pacifico, Raffaella Buzzetti
The aim of this study was to assess the relation of wrist circumference with changes in left ventricular (LV) structure in a population of overweight/obese children and adolescents. One hundred and six children and adolescents were consecutively enrolled. In all subjects body weight, height, wrist circumference, waist circumference, body mass index-standard deviation score, fasting glucose, insulin, lipid profile, and blood pressure were evaluated. All subjects underwent echocardiographic assessment, and the following parameters were evaluated: LV dimension at end diastole and LV dimension at end systole, LV posterior wall thickness at end diastole and LV posterior wall thickness at end systole, interventricular septal thickness at end diastole and interventricular septal thickness at end systole, LV mass, and epicardial adipose tissue (EAT)...
March 14, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29563352/local-thickness-of-epicardial-adipose-tissue-surrounding-the-left-anterior-descending-artery-is-a-simple-predictor-of-coronary-artery-disease-new-prediction-model-in-combination-with-framingham-risk-score
#9
Gulinu Maimaituxun, Michio Shimabukuro, Daiju Fukuda, Shusuke Yagi, Yukina Hirata, Takashi Iwase, Shoichiro Takao, Tomomi Matsuura, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masafumi Harada, Masataka Sata
BACKGROUND: Compared with global cardiac adiposity, the local accumulation of fat surrounding coronary arteries might have a more direct impact on coronary artery disease (CAD). Here, we compared the local epicardial adipose tissue (EAT) thickness and global cardiac adiposity volumes for predicting CAD.Methods and Results:A total of 197 consecutive subjects underwent 320-slice multi-detector computed tomography coronary angiography and were segregated into CAD (≥1 coronary artery branch stenosis ≥50%) and non-CAD groups...
March 21, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29548286/relationships-between-epicardial-adipose-tissue-thickness-and-adipo-fibrokine-indicator-profiles-post-myocardial-infarction
#10
Olga Gruzdeva, Evgenya Uchasova, Yulia Dyleva, Daria Borodkina, Olga Akbasheva, Ekaterina Belik, Viktoria Karetnikova, Natalia Brel, Alexander Kokov, Vasiliy Kashtalap, Olga Barbarash
BACKGROUND: Determination of the impact of visceral obesity and epicardial adipose tissue thickness on stimulating growth factor levels during hospitalization for myocardial infarction is of potential importance for predicting outcomes and assessing the development of cardiofibrotic changes associated with maladaptive myocardial remodeling. In this study, we aimed to investigate the relationships between epicardial adipose tissue thickness, adipokine profiles, and the stimulating growth factor 2/interleukin-33 signaling system during hospitalization for myocardial infarction, and with the cardiac fibrosis extent 1-year post-MI in patients with visceral obesity...
March 16, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29535556/thyroid-function-and-atrial-fibrillation-is-there-a-mediating-role-for-epicardial-adipose-tissue
#11
Daniel Bos, Arjola Bano, Albert Hofman, Tyler J VanderWeele, Maryam Kavousi, Oscar H Franco, Meike W Vernooij, Robin P Peeters, M Arfan Ikram, Layal Chaker
Background: The underlying mechanism of the association between thyroid function and atrial fibrillation (AF) is poorly understood, but epicardial adipose tissue (EAT) could be a promising mediator. Methods: In the 1995 participants (mean age 64.5 years) from the population-based Rotterdam Study, we measured thyroid function (thyroid-stimulating hormone, free thyroxine [FT4]) and performed computed tomography to quantify EAT volumes. All participants were followed for the occurrence of AF...
2018: Clinical Epidemiology
https://www.readbyqxmd.com/read/29512723/susceptibilities-of-epicardial-and-subcutaneous-fat-tissue-for-browning-gene-expression-and-diet-induced-volume-reduction-are-different
#12
Hiroshi Mikamo, Meizi Jiang, Mahito Noro, Yasuo Suzuki, Nobuyuki Hiruta, Hiroyuki Unoki-Kubota, Wolfgang J Schneider, Hideaki Bujo
The upregulation of brown or brown-like beige adipocytes is a potential strategy for the prevention or treatment of diabetes and coronary artery diseases in obese patients. Epicardial adipose tissue (EAT) differs significantly from subcutaneous fat tissue (SAT) in metabolic properties. To investigate properties of EAT further, thermogenesis gene expression was investigated in human autopsy and murine samples, and adipocytes differentiated from EAT mesenchymal cells. Subsequently, analyzed EAT volume alterations were observed to be associated with weight reduction in obese patients by imaging...
May 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29444599/correlation-between-epicardial-fat-thickness-and-aortic-valve-sclerosis
#13
Maryam Nabati, Maryam Favaedi, Masoud Kheirgoo, Jamshid Yazdani, Mozhdeh Dabirian
Background Epicardial fat is a true visceral fat deposit with adverse effects through the secretion of numerous proinflammatory and proatherogenic cytokines. Previous studies showed an association between aortic valve sclerosis and coronary artery disease. The aim of this study was to determine the correlation between epicardial fat thickness and aortic valve sclerosis. Method The study involved 225 patients who were admitted for coronary angiography due to new-onset angina. They underwent transthoracic echocardiography and epicardial fat thickness was determined...
March 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29439878/thickness-and-an-altered-mirna-expression-in-the-epicardial-adipose-tissue-is-associated-with-coronary-heart-disease-in-sudden-death-victims
#14
Josep Marí-Alexandre, Moises Barceló-Molina, Jorge Sanz-Sánchez, Pilar Molina, Jennifer Sancho, Yolanda Abellán, María Luisa Santaolaria-Ayora, Juan Giner, Luis Martínez-Dolz, Amparo Estelles, Aitana Braza-Boïls, Esther Zorio
INTRODUCTION AND OBJECTIVES: An increased epicardial adipose tissue (EAT) thickness has become a new risk factor for coronary heart disease (CHD). We aimed to study the role of EAT dysfunction as a CHD marker by focusing on its thickness and microRNA (miRNA) expression profile, and the potential factors possibly influencing them. METHODS: One hundred and fifty-five CHD sudden cardiac death victims and 84 non-CHD-sudden death controls were prospectively enrolled at autopsy...
February 10, 2018: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29433433/epicardial-adipose-tissue-is-related-to-arterial-stiffness-and-inflammation-in-patients-with-cardiovascular-disease-and-type-2-diabetes
#15
Shaween Al-Talabany, Ify Mordi, J Graeme Houston, Helen M Colhoun, Jonathan R Weir-McCall, Shona Z Matthew, Helen C Looker, Daniel Levin, Jill J F Belch, Fiona Dove, Faisel Khan, Chim C Lang
BACKGROUND: Epicardial adipose tissue (EAT) is an emerging cardio-metabolic risk factor and has been shown to correlate with adverse cardiovascular (CV) outcome; however the underlying pathophysiology of this link is not well understood. The aim of this study was to evaluate the relationship between EAT and a comprehensive panel of cardiovascular risk biomarkers and pulse wave velocity (PWV) and indexed left ventricular mass (LVMI) in a cohort of patients with cardiovascular disease (CVD) and diabetes compared to controls...
February 13, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29405193/-the-forensic-medical-characteristic-of-sudden-death-associated-with-metabolic-syndrome
#16
Yu I Pigolkin, Zh V Dorosheva, N S Oganesyan, D V Gornostaev
The detection of grade II-III central obesity on a corpse in conjunction with the identification of two additional criteria (such as arterial hypertension and impaired glucose tolerance) provides, if combined with the autopsy data (including the visual reduction of muscular mass, the increased total amount of the adipose tissue, gynecomastia in men together with hypertrophied abdominal adipose tissue accumulation, decreased face and body pilosis), a basis for diagnostics of metabolic syndrome (MS). The objective parameters for this purpose are waist circumference measurements, corpse weight and height, the degree of visceral obesity, narrowing of the renal arteries as a result of their compression by the surrounding adipose tissue, and accumulation of epicardial fat confirmed by the results of the biochemical analysis...
2018: Sudebno-meditsinskaia Ekspertiza
https://www.readbyqxmd.com/read/29399757/the-clinical-usefulness-of-epicardial-adipose-tissue-in-patients-with-high-intermediate-pre-test-probability-for-coronary-artery-disease
#17
Regayip Zehir, Ahmet Güner, Mert Ilker Hayiroglu, Tugba Kemaloğlu Oz, Altug Osken, Huseyin Aksu, Sennur Unal Dayi, Gultekin Faik Hobikoğlu
BACKGROUND: Epicardial adipose tissue [EAT] is thought to be associated with extension and severity of coronary artery disease [CAD] and echocardiographic measurement of EAT thickness has been considered to be a possible cardiovascular risk indicator. ESC Task Force recommends further non-invasive testing in patients with an intermediate pre-test probability [PTP] for the diagnosis of CAD. AIM: The purpose of this study was to evaluate the clinical usefulness of performing EAT measurements in patients with a high-intermediate PTP...
February 5, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29395494/an-increase-in-epicardial-fat-in-women-is-associated-with-thrombotic-risk
#18
Lourdes Basurto Acevedo, Susana Barrera Hernández, María de Jesús Fernández Muñoz, Renata Patricia Saucedo García, Ana Karen Rodríguez Luna, Carlos Martínez Murillo
INTRODUCTION: A decrease in fibrinolytic activity and an increase in the thickness of the epicardial adipose tissue have been observed in patients with coronary artery disease. The aim of this study was to determine the association between epicardial adipose tissue and fibrinolytic activity by measuring the concentration of plasminogen activator inhibitor-1 (PAI-1). METHODS: A cross-sectional study was conducted on 56 apparently healthy women aged 45 to 60 years...
January 29, 2018: Clínica e Investigación en Arteriosclerosis
https://www.readbyqxmd.com/read/29348672/soluble-lrp1-is-an-independent-biomarker-of-epicardial-fat-volume-in-patients-with-type-1-diabetes-mellitus
#19
David de Gonzalo-Calvo, Cristina Colom, David Vilades, Andrea Rivas-Urbina, Abdel-Hakim Moustafa, Montserrat Pérez-Cuellar, Jose Luis Sánchez-Quesada, Antonio Pérez, Vicenta LLorente-Cortes
Epicardial adipose tissue (EAT) is a metabolically active tissue intimately associated with metabolic syndrome and cardiovascular disease. Quantification of EAT volume is an interesting clinical tool for the evaluation of cardiometabolic disease. Nevertheless, current methodology presents serious disadvantages. The soluble form of the receptor LRP1 (sLRP1) is a non-invasive biomarker of EAT in general population. Here, we analysed the potential of circulating sLRP1 as biomarker of EAT volume in patients with type 1 diabetes mellitus (T1DM)...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343706/caloric-restriction-lowers-endocannabinoid-tonus-and-improves-cardiac-function-in-type-2-diabetes
#20
Huub J van Eyk, Linda D van Schinkel, Vasudev Kantae, Charlotte E A Dronkers, Jos J M Westenberg, Albert de Roos, Hildo J Lamb, J Wouter Jukema, Amy C Harms, Thomas Hankemeier, Mario van der Stelt, Ingrid M Jazet, Patrick C N Rensen, Johannes W A Smit
BACKGROUND/OBJECTIVES: Endocannabinoids (ECs) are associated with obesity and ectopic fat accumulation, both of which play a role in the development of cardiovascular disease (CVD) in type 2 diabetes (T2D). The effect of prolonged caloric restriction on ECs in relation to fat distribution and cardiac function is still unknown. Therefore, our aim was to investigate this relationship in obese T2D patients with coronary artery disease (CAD). SUBJECTS/METHODS: In a prospective intervention study, obese T2D patients with CAD (n = 27) followed a 16 week very low calorie diet (VLCD; 450-1000 kcal/day)...
January 17, 2018: Nutrition & Diabetes
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