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Epicardial adipose tissue measurement

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https://www.readbyqxmd.com/read/27910111/cystatin-c-and-epicardial-adipose-tissue-as-noninvasive-predictors-of-cardiovascular-risk-in-acromegaly
#1
Anna Aulinas, Iris Crespo, David Viladés, Ruben Leta, Eulàlia Urgell, Betina Biagetti, Susan M Webb, Elena Valassi
BACKGROUND: Acromegaly (ACRO) is associated with elevated cardiovascular risk, although the prevalence of coronary artery disease (CAD) is unclear. Increased epicardial adipose tissue (EAT) and elevated cystatin-C (Cys-C) levels are cardiovascular risk factors, also related to the progression of CAD in several populations. AIMS: To measure the severity and extent of CAD in patients with ACRO and to determine whether either EAT or Cys-C reflect higher cardiovascular risk in patients with ACRO than in healthy controls...
November 7, 2016: Clinical Endocrinology
https://www.readbyqxmd.com/read/27899941/influence-of-increased-epicardial-adipose-tissue-volume-on-1-year-in-stent-restenosis-in-patients-who-received-coronary-stent-implantation
#2
Ying Zhou, Hua-Wei Zhang, Feng Tian, Jin-Song Chen, Tian-Wen Han, Ya-Hang Tan, Jia Zhou, Tao Zhang, Jing Jing, Yun-Dai Chen
BACKGROUND: Epicardial adipose tissue (EAT) is significantly associated with the formation and composition of coronary atherosclerotic plaque, cardiac events and the clinical prognosis of coronary heart disease. But, whether increased EAT deposition may affect the incidence of in-stent restenosis (ISR) is currently unclear. This study used coronary computed tomography angiography (CCTA) as a mean to investigate whether increased EAT volume was associated with ISR. METHODS: A total of 364 patients who underwent 64-slice CCTA examination for the evaluation of suspected coronary artery disease, and subsequently underwent percutaneous coronary intervention (PCI) for the first time, and then accepted coronary angiography (CA) follow-up for ISR examination in one year, were retrospectively included in this study...
September 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/27888013/epicardial-adipose-tissue-in-the-general-middle-aged-population-and-its-association-with-metabolic-syndrome
#3
Álvaro Calabuig, Joaquín Barba, María Jesús Guembe, Javier Díez, Jesús Berjón, Eduardo Martínez-Vila, Pablo Irimia, Estefanía Toledo
INTRODUCTION AND OBJECTIVES: There is currently increasing interest in epicardial adipose tissue (EAT) as a marker of cardiovascular disease. Our purpose was to describe EAT, measured by transthoracic echocardiography, and to assess its association with metabolic syndrome (MS) in the RIVANA population-based study. METHODS: Physical examination was performed in 880 participants aged 45 to 74 years (492 of them with MS according to the harmonized definition). Fasting glucose, high-density lipoprotein cholesterol, triglyceride, and C-reactive protein concentrations were determined in a blood sample...
November 22, 2016: Revista Española de Cardiología
https://www.readbyqxmd.com/read/27878751/assessment-of-the-relationship-between-serum-paraoxonase-activity-and-epicardial-adipose-tissue-in-hemodialysis-patients
#4
Emad Abdallah, Samya El-Shishtawy, Nevine Sherif, Ahmed Ali, Omnia El-Bendary
PURPOSE: Paraoxonase-1 (PON-1) is a high-density lipoprotein-associated (HDL) enzyme, which has been shown to reduce susceptibility to low-density lipoprotein (LDL) peroxidation. Epicardial adipose tissue (EAT) is a marker of atherosclerosis. The aim of this study was to determine the relationship between PON-1 activity and EAT in hemodialysis (HD) patients. METHODS: This is a cross-sectional study conducted on 72 (43 males) HD patients with end-stage renal disease...
November 23, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27875723/orosomucoid-as-prognosis-factor-associated-with-inflammation-in-acute-or-nutritional-status-in-chronic-heart-failure
#5
Rosa M Agra, Alfonso Varela-Román, Rocío González-Ferreiro, Juan E Viñuela, Ana Castro-Pais, Ángel Fernández-Trasancos, Esther Díaz-Rodríguez, Ezequiel Álvarez, Marcos C Carreira, Felipe F Casanueva, José R González-Juanatey, Sonia Eiras
BACKGROUND: Inflammation and nutritional state are involved in the pathogenesis of heart failure (HF). OBJECTIVE: To study the contribution of alpha-1-acid-glycoprotein (AGP) to these factors and its prognostic value in acute (AHF) or chronic HF (CHF). METHODS: The observational study has included 147 patients (mean age 70years, 62% men) admitted to a cardiology department for HF and followed-up for an average 326.6±140.8days. Blood AGP values were measured by Enzyme-Linked ImmunoSorbent Assay...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27871080/the-association-between-premature-adrenarche-and-cardiovascular-risk-may-be-greater-than-expected
#6
Nurullah Çelik, Hayrullah Alp, Emine Çamtosun, Esma Alp, Sibel Çelik, Erhan Berk
AIM: The aim of this study was to investigate the cardiovascular risk of children with premature adrenarche (PA). METHODS: A total of 75 children (44 with PA and 31 control subjects) aged 6-10 years were included in the study. Their metabolic, anthropometric, and echocardiographic parameters were recorded and compared. RESULTS: Triglyceride, DHEA-SO4, and 17-hydroxyprogesterone levels were significantly higher in the PA group (p = 0.04, p = 0...
November 22, 2016: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/27864479/epicardial-adipose-tissue-and-cardiovascular-outcome-in-patients-with-acute-coronary-syndrome-undergoing-percutaneous-coronary-intervention
#7
Maximilian Tscharre, Christina Hauser, Miklos Rohla, Matthias K Freynhofer, Johann Wojta, Kurt Huber, Thomas W Weiss
AIMS: We investigated the association between epicardial adipose tissue (EAT) thickness and cardiovascular outcomes in a cohort of high-risk patients with acute coronary syndrome undergoing percutaneous coronary intervention. METHODS: Of 1198 patients undergoing percutaneous coronary intervention, transthoracic echocardiography was performed in 438 patients during the index hospitalization. EAT thickness was measured in the parasternal long-axis view perpendicularly on the free wall of the right ventricle at end-systole in three consecutive cardiac cycles and then averaged...
November 18, 2016: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/27790354/assosiation-of-epicardial-and-pericardial-fat-thickness-with-coronary-artery-disease
#8
Fereshteh Ghaderi, Ali Eshraghi, Alireza Sepehri Shamloo, Sareh Mousavi
INTRODUCTION: Visceral adipose tissue is a known important risk factor for coronary artery disease (CAD). While some studies have suggested relationship between epicardial fat thickness (EFT) and CAD, there are no adequate studies for pericardial fat thickness (PFT). The aim of this study was to determine the association of EFT and PFT with CAD. METHODS: This cross-sectional study was conducted on patients who were candidates for elective coronary artery angiography, referred to Emam Reza Hospital, Mashhad, Iran during Jan 2014-2016...
September 2016: Electronic Physician
https://www.readbyqxmd.com/read/27754052/os-14-09-epicardial-fat-thickness-and-neutrophil-to-lymphocyte-ratio-are-increased-in-the-non-dipper-pattern
#9
Kyoung Im Cho, Jung Ho Heo, Hyun Soo Kim, Sung Il Im, Tae Joon Cha
OBJECTIVE: Epicardial fat tissue reflects visceral adiposity and inflammation, and neutrophil to lymphocyte ratio (NLR) has been investigated as important inflammatory marker in cardiovascular disease. We aimed to investigate the relationship of echocardiographic epicardial fat thickness (EFT) and NLR with diurnal blood pressure (BP) changes in patients with recently diagnosed essential hypertension. DESIGN AND METHOD: A total of 647 hypertensive patients underwent echocardiography and 24-hours ambulatory BP monitoring...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27720272/epicardial-adipose-tissue-volume-and-left-ventricular-myocardial-function-using-3-dimensional-speckle-tracking-echocardiography
#10
Arnold C T Ng, Shi Yi Goo, Nicole Roche, Rob J van der Geest, William Y S Wang
BACKGROUND: Although epicardial adipose tissue (EAT) volume is associated with increased incidence of coronary artery disease (CAD), its role in myocardial systolic dysfunction is unclear. The present study aimed to identify independent determinants of EAT volume in patients without obstructive CAD, and to evaluate the association between EAT volume (vs other measures of obesity) and myocardial systolic strain analysis. METHODS: We prospectively recruited 130 patients without obstructive CAD on contrast-enhanced cardiac computed tomography imaging and normal left ventricular ejection fraction on 3-dimensional (3D) echocardiography...
June 23, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27714720/effect-of-epicardial-adipose-tissue-thickness-on-left-ventricular-diastolic-functions-in-patients-with-normal-coronary-arteries
#11
Mustafa Topuz, Ali Dogan
BACKGROUND: The aim of this study is to evaluate the effect of epicardial adipose tissue (EAT) thickness on left ventricular diastolic functions in patients with normal coronary arteries (NCA) proven by angiography. METHODS: We selected study patients who were referred to coronary angiography due to typical chest pain or atypical chest pain with a positive pre-test result for coronary artery disease. After coronary angiography, 85 patients had significant coronary lesion (≥50% stenosis) served as coronary artery disease (CAD) group, 82 patients had non-significant coronary lesion (<50% stenosis) and/or a coronary plaque served as non-significant CAD group and 83 patients had normal coronary arteries served as normal coronary artery (NCA) group...
October 7, 2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27665328/diagonal-earlobe-crease-associated-with-increased-epicardial-adipose-tissue-and-carotid-intima-media-thickness-in-subjects-free-of-clinical-cardiovascular-disease
#12
Murat Ziyrek, Sinan Şahin, Emrah Özdemir, Zeydin Acar, Serkan Kahraman
OBJECTIVE: Atherosclerotic coronary artery disease is a leading cause of death, worldwide. Diagonal earlobe crease (DELC) has been suggested as a simple, noninvasive marker of cardiovascular disease. Although epicardial adipose tissue (EAT) thickness and carotid intima media thickness (CIMT) are closely related to atherosclerosis, the relation between EAT, CIMT, and DELC had yet to be studied. The present objective was to analyze this association. METHODS: Subjects were apparently healthy individuals referred to the cardiology outpatient clinic...
September 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/27660804/automatic-pericardium-segmentation-and-quantification-of-epicardial-fat-from-computed-tomography-angiography
#13
Alexander Norlén, Jennifer Alvén, David Molnar, Olof Enqvist, Rauni Rossi Norrlund, John Brandberg, Göran Bergström, Fredrik Kahl
Recent findings indicate a strong correlation between the risk of future heart disease and the volume of adipose tissue inside of the pericardium. So far, large-scale studies have been hindered by the fact that manual delineation of the pericardium is extremely time-consuming and that existing methods for automatic delineation lack accuracy. An efficient and fully automatic approach to pericardium segmentation and epicardial fat volume (EFV) estimation is presented, based on a variant of multi-atlas segmentation for spatial initialization and a random forest classifier for accurate pericardium detection...
July 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27642972/os-14-09-epicardial-fat-thickness-and-neutrophil-to-lymphocyte-ratio-are-increased-in-the-non-dipper-pattern
#14
Kyoung Im Cho, Jung Ho Heo, Hyun Soo Kim, Sung Il Im, Tae Joon Cha
OBJECTIVE: Epicardial fat tissue reflects visceral adiposity and inflammation, and neutrophil to lymphocyte ratio (NLR) has been investigated as important inflammatory marker in cardiovascular disease. We aimed to investigate the relationship of echocardiographic epicardial fat thickness (EFT) and NLR with diurnal blood pressure (BP) changes in patients with recently diagnosed essential hypertension. DESIGN AND METHOD: A total of 647 hypertensive patients underwent echocardiography and 24-hours ambulatory BP monitoring...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27613385/assessment-of-epicardial-adipose-tissue-and-carotid-femoral-intima-media-thickness-in-insulin-resistance
#15
Cihan Altin, Leyla Elif Sade, Esin Gezmis, Mustafa Yilmaz, Necmi Ozen, Haldun Muderrisoglu
BACKGROUND: Metabolic syndrome is a combination of multiple cardiovascular (CV) risk factors including insulin resistance (IR). Carotid, femoral intima media thickness (IMT), and epicardial fat thickness (EFT) are considered as novel cardiometabolic risk factors. We aimed to test the hypothesis that carotid, femoral IMT, and EFT are increased in patients with IR. METHODS: We enrolled consecutively and prospectively 113 patients with IR. Then we collected data from an age- and sex-matched control group of 112 individuals without IR...
September 6, 2016: Journal of Cardiology
https://www.readbyqxmd.com/read/27564776/an-increase-in-epicardial-adipose-tissue-is-strongly-associated-with-carotid-intima-media-thickness-and-atherosclerotic-plaque-but-ldl-only-with-the-plaque
#16
Sinan Altan Kocaman, Oben Baysan, Mustafa Çetin, Tuğba Kayhan Altuner, Ezgi Polat Ocaklı, Murtaza Emre Durakoğlugil, Turan Erdoğan, Mustafa Remzi Karaoğuz
OBJECTIVE: Carotid intima-media thickness (CIMT) is reliable marker of subclinical atherosclerosis and cardiovascular events. Until today, there was no study that investigated whether epicardial adipose tissue (EAT), which is a surrogate for lipid depot in a special visceral tissue or circulating lipids, is more important for CIMT and atherosclerotic plaque. METHODS: Our study, having cross-sectional and prospective observational design, included 252 patients who were admitted to our outpatient clinic...
August 23, 2016: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/27542888/type-2-diabetes-is-associated-with-decreased-pgc1%C3%AE-expression-in-epicardial-adipose-tissue-of-patients-with-coronary-artery-disease
#17
Inmaculada Moreno-Santos, Luis Miguel Pérez-Belmonte, Manuel Macías-González, María José Mataró, Daniel Castellano, Miguel López-Garrido, Carlos Porras-Martín, Pedro L Sánchez-Fernández, Juan José Gómez-Doblas, Fernando Cardona, Eduardo de Teresa-Galván, Manuel Jiménez-Navarro
BACKGROUND: Although recent studies indicate that epicardial adipose tissue expresses brown fat-like genes, such as PGC1α, UCP1 and PRDM16, the association of these genes with type 2 diabetes mellitus (DM2) in coronary artery disease (CAD) remains unknown. METHODS: PGC1α, UCP1, and PRDM16 mRNAs expression levels were measured by real-time PCR in epicardial and thoracic subcutaneous adipose tissue from 44 CAD patients (22 with DM2 [CAD-DM2] and 22 without DM2 [CAD-NDM2]) and 23 non-CAD patients (NCAD)...
2016: Journal of Translational Medicine
https://www.readbyqxmd.com/read/27522371/relationship-between-soluble-receptor-for-advanced-glycation-end-products-srage-body-composition-and-fat-distribution-in-healthy-women
#18
Elena Dozio, Silvia Briganti, Alessandra Delnevo, Elena Vianello, Federica Ermetici, Francesco Secchi, Francesco Sardanelli, Lelio Morricone, Alexis E Malavazos, Massimiliano M Corsi Romanelli
PURPOSE: Soluble receptor for advanced glycation end products (sRAGE) is a decoy receptor which sequesters RAGE ligands and acts as a cytoprotective agent. To date, it is unclear whether the lower sRAGE levels observed in obesity are a marker of increased overall adiposity or reflect increases in particular fat depots. Therefore, we evaluated in healthy women the relationship among sRAGE and indicators of adiposity, including abdominal visceral (VAT) and epicardial visceral (EAT) adipose tissues, to explore the potential role of sRAGE as an earlier biomarker of cardiometabolic risk...
August 13, 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/27521222/relation-between-epicardial-adipose-and-aortic-valve-and-mitral-annular-calcium-determined-by-computed-tomography-in-subjects-aged-%C3%A2-65%C3%A2-years
#19
Talal S Alnabelsi, Yaser Alhamshari, Ramzi H Mulki, Jose N Codolosa, Nikoloz Koshkelashvili, Igor Goykhman, Gregg S Pressman, Abel Romero-Corral
Epicardial adipose tissue (EAT) has been linked to coronary artery calcium deposits and atherosclerotic disease. Mitral annular (MAC) and aortic valve calcium (AVC) have also been associated with atherosclerosis. This study examined the possible relation between EAT thickness and valvular calcium deposits. We included 294 patients aged ≥65 years who had noncontrast computed tomography scans of the chest. Mean age was 76 ± 7 years; 47% were men. Using reconstructed images, EAT thickness was measured at various locations...
October 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27506742/effects-of-lifestyle-intervention-on-left-ventricular-regional-myocardial-function-in-metabolic-syndrome-patients-from-the-resolve-randomized-trial
#20
Juan Serrano-Ferrer, Edward Crendal, Guillaume Walther, Agnes Vinet, Frédéric Dutheil, Geraldine Naughton, Bruno Lesourd, Robert Chapier, Daniel Courteix, Philippe Obert
AIMS: The purpose of our study was to determine the effect of lifestyle intervention on left ventricular (LV) regional myocardial function in patients with metabolic syndrome (MetS) and investigate the relationships of the changes in myocardial function to changes in epicardial adipose tissue (EAT), inflammatory profile and MetS components. METHODS: Eighty-seven MetS patients were enrolled in a 6month lifestyle intervention program based on dietary management and increased physical activity, and compared with 44 aged and sex-matched healthy controls...
September 2016: Metabolism: Clinical and Experimental
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