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Ying Sun, Yiming Pang, Jingxu Zhang, Zhiwen Li, Jufen Liu, Bin Wang
High-accuracy analyses of polycyclic aromatic hydrocarbons (PAHs) in lipid matrix-based biological samples are highly necessary. We investigated the cleanup performance of the commercially available molecularly imprinted polymers (MIPs) to analyze PAHs in various biological samples (i.e., butter, peanut oil, pork belly, and human umbilical cord), and compared this method with the commonly used gel permeation chromatography (GPC). After primary cleanup with a MIP or GPC column, the extracts were further cleaned with a neutral aluminum oxide column...
October 12, 2017: Analytical and Bioanalytical Chemistry
Sanjida Mahjabeen, Manolya K Hatipoglu, Vishal Chandra, Doris M Benbrook, Lucila Garcia-Contreras
Cervical dysplasia induced by the human papilloma virus (HPV) unpredictably progresses to cervical cancer. Therapeutic options are invasive and affect the patient's quality of life. SHetA2 has demonstrated therapeutic efficacy against human and murine HPV- induced tumors, but its oral bioavailability is <1%. An optimized vaginal suppository formulation can deliver SHetA2 in sufficient doses to prevent cervical dysplasia. The quality by design (QbD) approach was employed to optimize the suppository formulation consisting of cocoa butter as base with 5% Kolliphor and 40% SHetA2...
October 5, 2017: Journal of Pharmaceutical Sciences
Myoung Jin Oh, Young Hoon Cho, So Yoon Cha, Eun Ok Lee, Jin Wook Kim, Sun Ki Kim, Chang Seo Park
Ceramides in the human stratum corneum (SC) are a mixture of diverse N-acylated fatty acids (FAs) with different chain lengths. C24 is the major class of FAs of ceramides. However, there are also other classes of ceramides with diverse chain lengths of FAs, and these lengths generally range from C16 to C26. This study aimed to prepare several types of phytoceramide containing diverse chain lengths of N-acylated FAs and compare them with C18-ceramide N-stearoyl phytosphingosine (NP) in terms of their effects on the physiological properties of the SC...
2017: Clinical, Cosmetic and Investigational Dermatology
Jean-Philippe Drouin-Chartier, André J Tremblay, Julie Maltais-Giguère, Amélie Charest, Léa Guinot, Laurie-Eve Rioux, Steve Labrie, Michel Britten, Benoît Lamarche, Sylvie L Turgeon, Patrick Couture
Background: In a simulated gastrointestinal environment, the cheese matrix modulates dairy fat digestion. However, to our knowledge, the impact of the cheese matrix on postprandial lipemia in humans has not yet been evaluated.Objective: In healthy subjects, we compared the impact of dairy fat provided from firm cheese, soft cream cheese, and butter on the postprandial response at 4 h and on the incremental area under the curve (iAUC) of plasma triglycerides.Design: Forty-three healthy subjects were recruited to this randomized, crossover, controlled trial...
October 4, 2017: American Journal of Clinical Nutrition
Monise Helen Masuchi Buscato, Renato Grimaldi, Theo Guenter Kieckbusch
Symmetrical monounsaturated triacylglycerols-also known as SUS (saturated unsaturated saturated triacylglycerols)-are the main triacylglycerols present in cocoa butter (CB), exhibiting decisive influence in the tempering process conditions and sensorial characteristics in chocolate products. CBs with lower amounts of SUS do not crystallize adequately in chocolate processing, generating a low quality product with higher susceptibility to fat bloom formation. In this context, fractions with higher contents of SUS triacylglycerols were obtained by solvent fractionation of cocoa butter, under four operating conditions varying crystallization temperatures (17, 18, 20 and 22 °C) and sample/acetone solvent ratios (1:7 and 1:5, in w/v)...
September 2017: Journal of Food Science and Technology
Lee Ching Yong, Andrew R Gray, Alex Chisholm, Sook Ling Leong, Siew Ling Tey, Rachel C Brown
OBJECTIVE: Despite considerable evidence supporting the health benefits of regular nut consumption, nut intakes remain lower than recommended among many populations. Understanding how the general population perceives nuts could inform strategies to promote regular nut consumption and increase intakes among the general public. DESIGN: Cross-sectional study. Participants were invited to complete a questionnaire which included information on nut consumption and knowledge and perceptions of nuts...
October 2, 2017: Public Health Nutrition
Diana Barbosa Cunha, Ilana Nogueira Bezerra, Rosangela Alves Pereira, Rosely Sichieri
BACKGROUND: Away-from-home food intake has been associated with high rates of overweight among children and adolescents. However, there are no studies comparing at-home and away-from-home eating patterns among adolescents. OBJECTIVES: The objective of this paper was to identify at-home and away-from-home dietary patterns among adolescents in Brazil, and to evaluate the relationship between these patterns and body mass index (BMI) z-scores. DESIGN: Data from the Brazilian National Dietary Survey 2008-2009 were analyzed in this cross-sectional study...
September 28, 2017: Appetite
Ellen Schoener, Sarah Susanne Uebleis, Julia Butter, Michaela Nawratil, Claudia Cuk, Eva Flechl, Michael Kothmayer, Adelheid G Obwaller, Thomas Zechmeister, Franz Rubel, Karin Lebl, Carina Zittra, Hans-Peter Fuehrer
BACKGROUND: Insect vectors, namely mosquitoes (Diptera: Culicidae), are compulsory for malaria parasites (Plasmodium spp.) to complete their life cycle. Despite this, little is known about vector competence of different mosquito species for the transmission of avian malaria parasites. METHODS: In this study, nested PCR was used to determine Plasmodium spp. occurrence in pools of whole individuals, as well as the diversity of mitochondrial cytochrome b gene sequences in wild-caught mosquitoes sampled across Eastern Austria in 2013-2015...
September 29, 2017: Malaria Journal
Marina Pasquini, Andrea Osimani, Stefano Tavoletti, Itzhak Moreno, Francesca Clementi, Maria Federica Trombetta
Buffalo milk represents an indispensable source of nourishment in many parts of the world and it is the second most consumed milk worldwide. Buffalo milk is actually used for the production of many dairy products such as pasteurized or concentrated milk, butter, yogurt, ice-cream, dehydrated milk products and cheeses. Due to its high nutritional value and the presence of natural bioactive substances, buffalo milk can also provide health benefits to consumers. In Italy, buffalo milk is used mainly for cheese making, mozzarella PDO (Protected Designation of Origin), which is a highly valued dairy product...
September 29, 2017: Animal Science Journal, Nihon Chikusan Gakkaihō
Sihui Liang, Lilian M Were
Sunflower butter use as an allergen-free alternative to tree and legume nut butter in baking is limited by chlorogenic acid induced greening that occurs at alkaline pH. Limited information is available on controlling this greening in a food matrix. This study examined how different liquid sweeteners and relative humidity influenced greening of sunflower butter cookies. Doughs had similar initial pH (7.52-7.66) which increased to 8.44-9.13 after baking as ranked: xylitol>maple syrup>corn syrup>honey>agave syrup...
February 15, 2018: Food Chemistry
Timothy James Martin, Coen Butters, Linny Phuong
The Water Well Project is a health promotion charity that aims to improve the health literacy of individuals of refugee, asylum seeker and migrant backgrounds. Health literacy is an important predictor of health status, but many Australians cannot demonstrate functional health literacy, and individuals from culturally and linguistically diverse (CALD) backgrounds are at higher risk of poor health literacy. The primary participants of The Water Well Project's health education sessions are individuals of refugee, asylum seeker and migrant background, who are at risk of increased morbidity and mortality due to a range of factors...
September 28, 2017: Australian Health Review: a Publication of the Australian Hospital Association
Elizabeth A DiNapoli, Marie Anne Gebara, Terry Kho, Meryl A Butters, Ariel G Gildengers, Steven M Albert, Mary Amanda Dew, Kirk I Erickson, Charles F Reynolds, Jordan F Karp
BACKGROUND/OBJECTIVES: We investigated the prevalence and correlates of discrepancies between self-reported sleep quality (Pittsburgh Sleep Quality Index) and objective sleep efficiency (actigraphy) in older adults with mild cognitive impairment (MCI) and subsyndromal depression. METHODS: This was a secondary analysis of a clincial trial with 59 adults aged 60 years and older with MCI and subsyndromal depression. We included baseline data on participants' subjective sleep quality, objective sleep efficiency, depressive symptoms, insomnia diagnosis, and cognitive functioning...
January 1, 2017: Journal of Geriatric Psychiatry and Neurology
Scott M Thompson, Danielle E Jondal, Kim A Butters, Bruce E Knudsen, Jill L Anderson, Matthew P Stokes, Xiaoying Jia, Joseph P Grande, Lewis R Roberts, Matthew R Callstrom, David A Woodrum
PURPOSE: The aims of the present study were two-fold: first, to test the hypothesis that heat stress induces MET and EGFR signaling in hepatocellular carcinoma (HCC) cells and inhibition of this signaling decreases HCC clonogenic survival; and second, to identify signaling pathways associated with heat-stress induced MET signaling. MATERIALS AND METHODS: MET(+) and EGFR(+) HCC cells were pre-treated with inhibitors to MET, EGFR, PI3K/mTOR or vehicle and subjected to heat stress or control ± HGF or EGF growth factors and assessed by colony formation assay, Western blotting and/or quantitative mass spectrometry...
September 27, 2017: International Journal of Hyperthermia
H T Karim, D L Tudorascu, M A Butters, S Walker, H J Aizenstein, C Andreescu
This corrects the article DOI: 10.1038/tp.2017.180.
September 26, 2017: Translational Psychiatry
Bashar Amer, Morten Rahr Clausen, Hanne Christine Bertram, Mette Bohl, Caroline Nebel, Hong Zheng, Thomas Skov, Mette Krogh Larsen, Søren Gregersen, Kjeld Hermansen, Trine Kastrup Dalsgaard
SCOPE: We aimed to investigate whether changes in the metabolome could explain observed changes in body composition in overweight adults after consumption of butter with high level of medium-chain fatty acids (MCFAs) in combination with casein or whey. METHODS AND RESULTS: With GC-ToF and LC-Q/MS, we analyzed metabolites in plasma and urine from a 12-weeks randomized double-blinded human intervention including 52-abdominally overweight adults. The participants consumed 63 g/day of milk fat (high or low in MCFAs) and 60 g/day of protein (whey or casein)...
September 26, 2017: Molecular Nutrition & Food Research
Claire Bourlieu, David Cheillan, Marielle Blot, Patricia Daira, Michèle Trauchessec, Séverine Ruet, Jean-Yves Gassi, Eric Beaucher, Benoit Robert, Nadine Leconte, Saïd Bouhallab, Frédéric Gaucheron, Geneviève Gésan-Guiziou, Marie-Caroline Michalski
Bioactive lipids of the milk fat globule membrane become concentrated in two co-products of the butter industry, buttermilk and butterserum. Their lipid composition is detailed here with special emphasis on sphingolipid composition of nutritional interest, determined using GC, HPLC and tandem mass spectrometry. Butterserum was 2.5 times more concentrated in total fat than buttermilk, with 7.7±1.5vs 19.5±2.9wt% and even more concentrated in polar lipids, with 1.4±0.2vs 8.5±1.1wt%. Both ingredients constitute concentrated sources of sphingomyelin (3...
February 1, 2018: Food Chemistry
Benjamin L Handen, Evdokia Anagnostou, Michael G Aman, Kevin B Sanders, James Chan, Jill A Hollway, Jessica Brian, L Eugene Arnold, Lucia Capano, Craig Williams, Jessica A Hellings, Eric Butter, Deepali Mankad, Rameshwari Tumuluru, Jessica Kettel, Cassandra R Newsom, Naomi Peleg, Dina Odrobina, Sarah McAuliffe-Bellin, Sarah Marler, Taylor Wong, Alexis Wagner, Stasia Hadjiyannakis, Eric A Macklin, Jeremy Veenstra-VanderWeele
OBJECTIVE: A previous study reported on a 16-week placebo-controlled, randomized clinical trial (RCT) of metformin for weight stabilization in 61 children and adolescents 6 to 17 years old with autism spectrum disorder who were prescribed atypical antipsychotics. The present study describes the results of a 16-week open-label extension. METHOD: Fifty-two participants from the acute trial (85%) entered the extension; 22 had been on metformin during the initial RCT and 30 had been on placebo...
October 2017: Journal of the American Academy of Child and Adolescent Psychiatry
Rochelle P Walensky
No abstract text is available yet for this article.
September 15, 2017: Journal of Infectious Diseases
Joseph C Anderson, Lynn F Butterly, Christina M Robinson, Julia E Weiss, Christopher Amos, Amitabh Srivastava
BACKGROUND & AIMS: Surveillance guidelines for serrated polyps (SPs) are based on limited data on longitudinal outcomes of patients. We used the New Hampshire Colonoscopy Registry to evaluate risk of clinically important metachronous lesions associated with SPs, detected during index colonoscopies. METHODS: We collected data from a population-based colonoscopy registry that has been collecting and analyzing data on colonoscopies across the state of New Hampshire since 2004, including rates of adenoma and serrated polyp detection...
September 16, 2017: Gastroenterology
Roya Ostovar, Thomas Claus, Martin Hartrumpf, Ralf Uwe Kuehnel, Christian Braun, Christian Butter, Johannes M Albes
No abstract text is available yet for this article.
September 18, 2017: Thoracic and Cardiovascular Surgeon
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