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https://www.readbyqxmd.com/read/29244538/associations-between-dietary-patterns-and-longitudinal-quality-of-life-changes-in-colorectal-cancer-patients-the-colocare-study
#1
Biljana Gigic, Heiner Boeing, Reka Toth, Jürgen Böhm, Nina Habermann, Dominique Scherer, Petra Schrotz-King, Clare Abbenhardt-Martin, Stephanie Skender, Hermann Brenner, Jenny Chang-Claude, Michael Hoffmeister, Karen Syrjala, Paul B Jacobsen, Martin Schneider, Alexis Ulrich, Cornelia M Ulrich
Quality of life (QoL) is an important clinical outcome in cancer patients. We investigated associations between dietary patterns and QoL changes in colorectal cancer (CRC) patients. The study included 192 CRC patients with available EORTC QLQ-C30 data before and 12 months post-surgery and food frequency questionnaire data at 12 months post-surgery. Principal component analysis was used to identify dietary patterns. Multivariate regression models assessed associations between dietary patterns and QoL changes over time...
December 15, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/29244022/the-structural-basis-for-dynamic-dna-binding-and-bridging-interactions-which-condense-the-bacterial-centromere
#2
Gemma Lm Fisher, César L Pastrana, Victoria A Higman, Alan Koh, James A Taylor, Annika Butterer, Timothy Craggs, Frank Sobott, Heath Murray, Matthew P Crump, Fernando Moreno-Herrero, Mark S Dillingham
The ParB protein forms DNA bridging interactions around parS to condense DNA and earmark the bacterial chromosome for segregation. The molecular mechanism underlying the formation of these ParB networks is unclear. We show here that while the central DNA binding domain is essential for anchoring at parS, this interaction is not required for DNA condensation. Structural analysis of the C-terminal domain reveals a dimer with a lysine-rich surface that binds DNA non-specifically and is essential for DNA condensation in vitro...
December 15, 2017: ELife
https://www.readbyqxmd.com/read/29236390/serum-glycomarkers-of-endoplasmic-reticulum-and-lysosomal-endosomal-system-stress-in-human-healthy-aging-and-diseases
#3
I U Pismenetskaya, T D Butters
To verify the idea that extracellular free oligosaccharides might be able to reflect the functional status of the endoplasmic reticulum (ER) and lysosomal-endosomal system, HPLC-profiles of serum-derived free oligosaccharides (FOS) in human healthy aging, acute myeloproliferative neoplasms, and cardiovascular pathologies were compared with intracellular glycans. After plasma deproteinization and FOS purification the oligosaccharides were labelled with anthranilic acid, separated into the neutral and charged with QAE Sephadex (Q25-120) chromatography and analysed using high-performance liquid chromatography (HPLC)...
January 2017: Ukrainian Biochemical Journal
https://www.readbyqxmd.com/read/29235143/allostatic-load-but-not-medical-burden-predicts-memory-performance-in-late-life-bipolar-disorder
#4
REVIEW
Sophie R Vaccarino, Tarek K Rajji, Ariel G Gildengers, Sarah E S Waters, Meryl A Butters, Mahesh Menon, Daniel M Blumberger, Aristotle N Voineskos, Dielle Miranda, Benoit H Mulsant
OBJECTIVE: Older patients with bipolar disorder (BD) present with variable degrees of cognitive impairment. Over time, stress, mood episodes, and comorbidities increase the body's allostatic load. We assessed the extent to which allostatic load vs more traditional measures of medical burden account for the heterogeneity in cognition in this population. METHODS: Thirty-five older euthymic patients with BD and 30 age-equated, gender-equated, and education-equated comparison participants were administered a comprehensive assessment including a neuropsychological battery, and 9 physiological measures to determine allostatic load...
December 13, 2017: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29234699/dataset-on-analysis-of-dyeing-property-of-natural-dye-from-thespesia-populnea-bark-on-different-fabrics
#5
Kuchekar Mohini, Landge Tejashree, Navghare Vijay
The natural dyes separated from plants are of gaining interest as substitutes for synthetic dyes in food and cosmetics. Thespesia populnea (T. populnea) is widely grown plant and used in the treatment of various diseases. This study was aimed to separate natural dye from T. populnea bark and analysis of its dyeing property on different fabrics. In this investigation pharmacognostic study was carried out. The pharmacognostic study includes morphological study, microscopical examination, proximate analysis along with the phytochemical study...
February 2018: Data in Brief
https://www.readbyqxmd.com/read/29229244/the-functional-properties-and-structural-characteristics-of-deamidated-and-succinylated-wheat-gluten
#6
Yanhong Liu, Lingling Zhang, Yongxiang Li, Yang Yang, Fei Yang, Shuo Wang
Wheat gluten protein (WGP) was modified by deamidation and succinylation to improve its functional properties. The properties of deamidated and succinylated WGP were compared with those of unmodified WGP, deamidated WGP and succinylated WGP. Structural analysis was carried out with FTIR. Surface visualization was carried out with SEM and the thermal stability was determined by DSC. The results showed that an acylation level of 73.64% produced the optimal properties for modified WGP. After modification, its functional properties were significantly improved...
December 8, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29228518/childhood-trauma-is-associated-with-poorer-cognitive-performance-in-older-adults
#7
Andrew J Petkus, Eric J Lenze, Meryl A Butters, Elizabeth W Twamley, Julie Loebach Wetherell
OBJECTIVE: Childhood trauma is common and associated with both worse cognitive performance and disruption to the hypothalamic-pituitary-adrenal axis in younger adults. The extent to which these associations persist into older adulthood remains unknown. The aim of this study was to investigate self-reported childhood trauma in relation to cognitive performance, and the extent to which cortisol explained this association, in 2 independent samples of older adults. METHODS: In this cross-sectional study, participants in the discovery sample (N = 76) consisted of older adults with a DSM-IV diagnosis of generalized anxiety disorder (N = 57) and age-equated psychiatrically healthy comparison subjects (N = 19) who were referred largely through primary care clinics between 2004-2006...
December 5, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29212345/a-pilot-investigation-of-an-ios-based-app-for-toilet-training-children-with-autism-spectrum-disorder
#8
Daniel W Mruzek, Stephen McAleavey, Whitney A Loring, Eric Butter, Tristram Smith, Erin McDonnell, Lynne Levato, Courtney Aponte, Rebekah P Travis, Rachel E Aiello, Cora M Taylor, Jonathan W Wilkins, Patricia Corbett-Dick, Dianne M Finkelstein, Alyssa M York, Katherine Zanibbi
We developed an iOS-based app with a transmitter/disposable sensor and corresponding manualized intervention for children with autism spectrum disorder. The app signaled the onset of urination, time-stamped accidents for analysis, reminded parents to reinforce intervals of continence, provided a visual outlet for parents to communicate reinforcement, and afforded opportunity for timely feedback from clinicians. We compared this intervention with an intervention that uses standard behavioral treatment in a pilot randomized controlled trial of 33 children with autism spectrum disorder aged 3-6 years with urinary incontinence...
December 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29210028/antimicrobial-peptides-sourced-from-post-butter-processing-waste-yak-milk-protein-hydrolysates
#9
Jinjin Pei, Hai Jiang, Xinsheng Li, Wengang Jin, Yanduo Tao
Yak butter is one of the most important foods for the Tibetan people. Of note, its production yields waste yak milk as a by-product. In this work, waste yak milk protein hydrolysates made via Pepsin hydrolysis were shown to have antimicrobial activity. Furthermore, an innovative method of magnetic liposome adsorption combined with reversed-phase high performance liquid chromatography (RP-HPLC) was developed to screen for and purify the antimicrobial peptides. Two antimicrobial peptides were obtained and their amino acid sequences were determined by N-sequencing, namely Arg-Val-Met-Phe-Lys-Trp-Ala and Lys-Val-Ile-Ser-Met-Ile...
December 6, 2017: AMB Express
https://www.readbyqxmd.com/read/29209958/moxibustion-therapy-in-traditional-mongolian-medicine
#10
Tae-Hun Kim, Do-Hoon Kim, Seong Gyu Lee
From the medical history of traditional Eastern Asian and Tibetan medicine, the origin and development of moxibustion seems to be closely related to Mongolia. To explore the current clinical practice of moxibustion in Mongolia, we visited a teaching hospital, the Traditional Medical Science, Technology and Production Corporation of Mongolia, in February 2014. Many types of moxibustion are found to be used, and various modalities and methods are practiced based on the principles of traditional Mongolian medicine...
December 5, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29209786/prognostic-value-of-preprocedural-6-min-walk-test-in-patients-undergoing-transcatheter-mitral-valve-repair-insights-from-the-german-transcatheter-mitral-valve-interventions-registry
#11
Jakob Ledwoch, Jennifer Franke, Edith Lubos, Peter Boekstegers, Miriam Puls, Taoufik Ouarrak, Stephan von Bardeleben, Christian Butter, Joachim Schofer, Ralf Zahn, Hüsseyin Ince, Jochen Senges, Horst Sievert
AIMS: The 6-min walk test (6 MWT) has been established as an important tool for functional assessment in heart failure patients. However, its prognostic impact on the outcome in subjects with mitral regurgitation undergoing transcatheter mitral valve repair is unknown. METHODS: This present work represents a sub-analysis of the German, prospective, multicenter, Transcatheter Mitral Valve Interventions (TRAMI) registry. Of the main study cohort (n = 828) 326 patients underwent 6 MWT prior to the procedure...
December 5, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29202922/simultaneous-analysis-of-multiple-allergens-in-food-products-by-lc-ms-ms
#12
Lee Sun New, Andre Schreiber, Jianru Stahl-Zeng, Hua-Fen Liu
There is currently no cure for food allergies, and sufferers can only rely on the correct labeling of foods toavoid allergens. Hence, it is important that analytical methods are sensitive and accurate enough to screen for the presence of multiple allergens in food products. In this study, we developed an LC-tandem MS method that is able to simultaneously screen or quantify the signature tryptic peptides of multiple allergen commodities. This method is capable of screening and identifying egg white, skim milk, peanut, soy, and tree nuts (almond, Brazil nut, cashew, hazelnut, pecan, pine nut, pistachio, and walnut) at a detection limit of 10 ppm in incurred bread and cookies...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29194613/comparison-of-vegetable-shortening-and-cocoa-butter-as-vehicles-for-cortisol-manipulation-in-salmo-trutta
#13
K Birnie-Gauvin, K S Peiman, M H Larsen, K Aarestrup, K M Gilmour, S J Cooke
This study demonstrates that vegetable shortening and cocoa butter are two effective vehicles for intraperitoneal cortisol implants in juvenile teleosts, specifically brown trout Salmo trutta, residing in north temperate freshwater environments. Each vehicle showed a different pattern of cortisol elevation. Vegetable shortening was found to be a more suitable vehicle for long-term cortisol elevation [elevated at 3, 6 and 9 days post treatment (dpt)], while cocoa butter may be better suited for short-term cortisol elevation (only elevated at 3 dpt)...
November 30, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/29191323/transcatheter-aortic-valve-replacement-in%C3%A2-pure-native-aortic-valve-regurgitation
#14
MULTICENTER STUDY
Sung-Han Yoon, Tobias Schmidt, Sabine Bleiziffer, Niklas Schofer, Claudia Fiorina, Antonio J Munoz-Garcia, Ermela Yzeiraj, Ignacio J Amat-Santos, Didier Tchetche, Christian Jung, Buntaro Fujita, Antonio Mangieri, Marcus-Andre Deutsch, Timm Ubben, Florian Deuschl, Shingo Kuwata, Chiara De Biase, Timothy Williams, Abhijeet Dhoble, Won-Keun Kim, Enrico Ferrari, Marco Barbanti, E Mara Vollema, Antonio Miceli, Cristina Giannini, Guiherme F Attizzani, William K F Kong, Enrique Gutierrez-Ibanes, Victor Alfonso Jimenez Diaz, Harindra C Wijeysundera, Hidehiro Kaneko, Tarun Chakravarty, Moody Makar, Horst Sievert, Christian Hengstenberg, Bernard D Prendergast, Flavien Vincent, Mohamed Abdel-Wahab, Luis Nombela-Franco, Miriam Silaschi, Giuseppe Tarantini, Christian Butter, Stephan M Ensminger, David Hildick-Smith, Anna Sonia Petronio, Wei-Hsian Yin, Federico De Marco, Luca Testa, Nicolas M Van Mieghem, Brian K Whisenant, Karl-Heinz Kuck, Antonio Colombo, Saibal Kar, Cesar Moris, Victoria Delgado, Francesco Maisano, Fabian Nietlispach, Michael J Mack, Joachim Schofer, Ulrich Schaefer, Jeroen J Bax, Christian Frerker, Azeem Latib, Raj R Makkar
BACKGROUND: Limited data exist about safety and efficacy of transcatheter aortic valve replacement (TAVR) in patients with pure native aortic regurgitation (AR). OBJECTIVES: This study sought to compare the outcomes of TAVR with early- and new-generation devices in symptomatic patients with pure native AR. METHODS: From the pure native AR TAVR multicenter registry, procedural and clinical outcomes were assessed according to VARC-2 criteria and compared between early- and new-generation devices...
December 5, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29186859/peanuts-aflatoxins-and-undernutrition-in-children-in-sub-saharan-africa
#15
REVIEW
Innocent Mupunga, Pamella Mngqawa, David R Katerere
Peanuts (Arachis hypogaea) is an important and affordable source of protein in most of Sub-Saharan Africa (SSA) and a popular commodity and raw material for peanut butter, paste and cooking oil. It is a popular ingredient for foods used at the point of weaning infants from mother's milk. It is at this critical point that childhood undernutrition occurs and the condition manifests as stunting, wasting and growth restriction and accounts for nearly half of all deaths in children under five years of age in SSA...
November 26, 2017: Nutrients
https://www.readbyqxmd.com/read/29178175/effect-of-dairy-cow-crossbreeding-on-selected-performance-traits-and-quality-of-milk-in-first-generation-crossbreds
#16
Kamila Puppel, Ewa Bogusz, Marcin Gołębiewski, Teresa Nałęcz-Tarwacka, Beata Kuczyńska, Jan Slósarz, Arkadiusz Budziński, Paweł Solarczyk, Małgorzata Kunowska-Slósarz, Tomasz Przysucha
The main goal of crossbreeding Holstein-Friesian (HF) cows with bulls of other dairy or combined breeds is to improve their performance traits. Thus, the aim of this investigation was to compare the dairy performance traits of first generation crossbreds produced by crossbreeding Polish HF cows with bulls of other breeds (Norman, Norwegian Red, Danish Red, Brown Swiss, Montbeliarde, and Simmental). This was done by analyzing the fatty acid profile and technological quality of the milk from these first generation crossbreds...
November 27, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29168062/tree-nut-peanut-and-peanut-butter-intake-and-risk-of-postmenopausal-breast-cancer-the-netherlands-cohort-study
#17
Piet A van den Brandt, Lisette Nieuwenhuis
PURPOSE: Nut intake has been associated with reduced mortality and risk of cardiovascular diseases, but there is only limited evidence on cancer. We investigated the relationship between nut intake and risk of postmenopausal breast cancer, and estrogen/progesterone receptor (ER/PR) subtypes. METHODS: In The Netherlands Cohort Study, 62,573 women aged 55-69 years provided information on dietary and lifestyle habits in 1986. After 20.3 years of follow-up, 2,321 incident breast cancer cases and 1,665 subcohort members were eligible for multivariate case-cohort analyses...
November 22, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/29164390/nutrition-and-mobility-predict-all-cause-mortality-in-patients-12%C3%A2-months-after-transcatheter-aortic-valve-implantation
#18
Sarah Eichler, Annett Salzwedel, Axel Harnath, Christian Butter, Karl Wegscheider, Mihai Chiorean, Heinz Völler, Rona Reibis
BACKGROUND: The aim of the study was to determine pre-interventional predictors for all-cause mortality in patients after transcatheter aortic valve implantation (TAVI) with a 12-month follow-up. METHODS: From 10/2013 to 07/2015, 344 patients (80.9 ± 5.0 years, 44.5% male) with an elective TAVI were consecutively enrolled prospectively in a multicentre cohort study. Prior to the intervention, sociodemographic parameters, echocardiographic data and comorbidities were documented...
November 21, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29153516/determination-of-lactadherin-concentration-in-dairy-by-products-by-elisa-effect-of-heat-treatment-and-hydrolysis
#19
Daniel Ripollés, José A Parrón, Javier Fraguas, Miguel Calvo, María D Pérez, Lourdes Sánchez
Lactadherin is a peripheral glycoprotein of the milk fat globule membrane with several attributed biological activities. In this study, we developed an indirect competitive ELISA to determine lactadherin concentration by using a rabbit polyclonal antiserum. The ELISA was applied to quantify lactadherin in several dairy by-products. Of the products tested, raw and commercial buttermilk had the highest concentrations of lactadherin (6.79 and 5.27 mg/g of product, respectively), followed by commercial butter serum (4...
November 15, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29153184/a-100-year-review-yogurt-and-other-cultured-dairy-products
#20
Kayanush J Aryana, Douglas W Olson
The history of the last 100 years of the science and technology of yogurt, sour cream, cultured butter, cultured buttermilk, kefir, and acidophilus milk has been one of continuous development and improvement. Yogurt leads the cultured dairy product category in terms of volume of production in the United States and recent research activity. Legal definitions of yogurt, sour cream and acidified sour cream, and cultured milk, including cultured buttermilk, are presented in the United States Code of Federal Regulations and summarized here...
December 2017: Journal of Dairy Science
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