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Laryngeal cancer and laryngeal tuberculosis

Lindsay A Petty, Alexander J Gallan, Jordan A Detrick, Jessica P Ridgway, Jeffrey Mueller, Jennifer Pisano
Candida dubliniensis is an uncommon species of Candida which has been implicated in fungal pneumonia only very rarely. We present the case of a 75-year-old man with laryngeal cancer undergoing chemotherapy on broad-spectrum antibiotics and tuberculosis therapy with blood and endotracheal cultures positive for C. dubliniensis. Subsequent autopsy was performed with postmortem lung cultures positive for C. dubliniensis and lung histopathology demonstrating an invasive fungal infection. Molecular analysis of the lung tissue confirmed the identity of the fungi as C...
October 2016: Mycopathologia
F Rusu-Cordunean, A T Cernomaz, Mădălina Lavinia Berlea, D Ferariu, B D Grigoriu
Lung cancer has a very dismal prognosis and careful diagnosis and staging is of outmost importance. EBUS has become a cornerstone investigation for diagnosis and staging and current guidelines stress that there is a steep learning curve when introducing this tech- nique in practice (only 30 procedures are considered necessary). Over a period of 10 months a total of 21 patients have been addressed to our unit for an EBUS TBNA procedure. Only three were referred for staging purposes (for lung, digestive and cervix cancers) the others being primary diagnostic approaches where simpler procedures had previously failed...
January 2015: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Antoni Bruzgielewicz, Anna Rzepakowska, Ewa Osuch-Wójcikewicz, Kazimierz Niemczyk, Rafał Chmielewski
INTRODUCTION: The aim of our retrospective study was to review the clinical and epidemiological presentation of head and neck tuberculosis. MATERIAL AND METHODS: We analyzed the history of 73 patients with head and neck tuberculosis hospitalized in the Department of Otolaryngology, Medical University of Warsaw, between 1983 and 2009. RESULTS: We found that 26 (35.6%) patients presented with lymph node tuberculosis, 20 (27.4%) with laryngeal tuberculosis, 10 (13...
December 22, 2014: Archives of Medical Science: AMS
Pablo Young, Marcelo A Bravo, María G González, Bárbara C Finn, Mariano A Quezel, Julio E Bruetman
Armand Trousseau (1801-1867) was born in Tours, France on October 14, 1801. He graduated as a physician in the same city under the direction of Pierre Bretonneau and received his doctorate in 1825 in Paris. He was the first physician to practice tracheotomy in diphtheria and perform thoracenteses to remove air or fluid from the pleural space. He recommended tracheal intubation in different scenarios. He described the first cases of laryngeal tuberculosis and the presence of carpopedal spasm in hypocalcemia, a sign that has his name...
October 2014: Revista Médica de Chile
F El Ayoubi, I Chariba, A El Ayoubi, S Chariba, L Essakalli
INTRODUCTION: Tuberculosis is a chronic bacterial infection caused by Mycobacterium tuberculosis, usually affecting the lung, but very rare cases of isolated laryngeal tuberculosis have been reported. PURPOSE: To demonstrate the importance of considering the diagnosis of this disease, which presents with very variable and sometimes misleading clinical and endoscopic features, but for which medical treatment is very effective. MATERIAL AND METHODS: This retrospective study was based on ten cases of laryngeal tuberculosis managed between January 2004 and December 2009...
December 2014: European Annals of Otorhinolaryngology, Head and Neck Diseases
M K Masud, S M Ahmad, F Ferdouse, M R Bhuiyan, S K Paul, M A Litu, S Sarkar
Histoplasma capsulatum is an endemic granulomatous fungus disease. Involving the larynx of an immunocompetent patient with this is a rare manifestation. A sixty years old farmer who was previously diagnosed and treated as pulmonary tuberculosis was presented as a progressive change of voice and intermittent attack of unproductive cough with no history of stridor and fever for last 7 months. Clinical and imaging investigations were suggestive of laryngeal tuberculosis or laryngeal neoplasm. Laryngoscopy revealed edema, erythema and leukoplakia of the right vocal cord...
July 2014: Mymensingh Medical Journal: MMJ
Marcello C Ambrogi, Olivia Fanucchi, Stylianos Korasidis, Federico Davini, Raffaello Gemignani, Fabio Guarracino, Franca Melfi, Alfredo Mussi
OBJECTIVE: During the past 20 years, the use of video-assisted thoracoscopic surgery has increased as an important minimally invasive tool. To further reduce its invasiveness, after a preliminary experience, we decided to use a nonintubated spontaneous breathing general anesthesia, for video-assisted thoracoscopic surgery resection of lung nodule, using a laryngeal mask (LMA). This study aimed to verify the safety and the feasibility of this technique. METHODS: Twenty consecutive patients who underwent thoracoscopic wedge of lung nodule under spontaneous breathing general anesthesia with LMA are the subjects of this study...
July 2014: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
Leonardo F Jurado, Diana M Palacios, Johanna Alvarez, Margarita Baldión, Guillermo Campos
Primary laryngeal tuberculosis is a rare disease with a wide variety of clinical manifestations. We report the case of an ear-nose and throat diabetic physician with primary laryngeal tuberculosis. The diagnosis of laryngeal cancer had been considered before in another institution, and at the patient's admission, he only presented dysphonia with a six-month evolution. The vocal cord histological examination showed granulomas, giant cells, fibrosis and necrosis, and the Ziehl-Neelsen staining showed acid-alcohol resistant bacilli...
January 2014: Biomédica: Revista del Instituto Nacional de Salud
Shu-yi Wang, Jia-xing Zhu
OBJECTIVE: To study the clinicopathologic features, histologic diagnosis and differential diagnosis of primary mucosal tuberculosis (TB) in the head and neck region. METHODS: Forty-seven cases of primary mucosal TB of the head and neck region were studied by hematoxylin-eosin and Ziehl-Neelsen stains. The clinical and pathologic features were analyzed with review of the literature. RESULTS: The patients included 26 male and 21 female, with mean age 47...
October 2013: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
Anwar Suhail, Muhammad Sheharyar Ahmed, Zain-ul-Abdeen Sobani, Shahzad Ghaffar
Tuberculosis (TB) accounts for the highest number of mortalities among infectious diseases worldwide. Laryngeal TB is an extremely rare presentation of TB. It has many similarities to laryngeal carcinoma, one of the three most common cancers among males in the city, with an age standardized rate of 8.6. The associated risk factors of laryngeal carcinoma i.e. smoking, paan, betel nut usage and alcohol use also tend to be concentrated in the same demographic background as that of TB, creating a diagnostic dilemma...
February 2012: JPMA. the Journal of the Pakistan Medical Association
Hongtian Wang, Zongxi Bai, Keqin Wang, Langjiebu Suo, Xingwen Liu, Yuebing Ma, Chengpo Zhu, Yongsheng Lin, Benwei Xie, Suzhi Li
OBJECTIVE: To improve the diagnostic and therapeutic efficiency for secondary laryngeal tuberculosis through an analysis on the clinical features of patients with this disease. METHOD: A retrospective study was made among 49 cases with laryngeal tuberculosis treated in Tibetan General Hospital of Chinese PLA, and the clinical data were carefully analyzed to summarize the clinical experience of this disease. RESULT: Of 49 patients, 24 cases had 1 year history, 11 cases had 1 to 3 years, 9 cases had 3 to 5 years, 5 cases had 5 years or more...
November 2011: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Sun Wha Song, Beom Cho Jun, Kwang Jae Cho, Sungwon Lee, Young Joo Kim, Seog Hee Park
PURPOSE: To discuss computed tomography (CT) evaluation of the etiology of vocal cord paralysis (VCP) due to thoracic diseases. MATERIALS AND METHODS: From records from the past 10 years at our hospital, we retrospectively reviewed 115 cases of VCP that were evaluated with CT. Of these 115 cases, 36 patients (23 M, 13 F) had VCP due to a condition within the thoracic cavity. From these cases, we collected the following information: sex, age distribution, side of paralysis, symptom onset date, date of diagnosis, imaging, and primary disease...
September 2011: Yonsei Medical Journal
Jerzy Kuczkowski, Lukasz Plichta, Czesław Stankiewicz
This article will attempt to review the historical and scientific literature pertaining to the life and work of Felix Semon (1849-1921). Sir Felix Semon was one of the most distinguished figures in the early development of laryngology. He was an astute researcher of laryngeal pathophysiology and an active participant in laryngological scientific societies. Felix Semon was a talented doctor and was one of the most esteemed laryngologists in London for 35 years (1875-1910). Primarily, his scientific interests included complications after thyroid surgery, laryngeal cancer, tuberculosis and motor innervation of the larynx, and movement disorders of the larynx...
January 2012: Journal of Voice: Official Journal of the Voice Foundation
Tun-Chieh Chen, Po-Liang Lu, Chih-Jen Yang, Wei-Ru Lin, Chun-Yu Lin, Ruwen Jou, Ming-Chu Feng, Tung-Heng Wang, Chi-Kung Ho, Jhi-Jhu Hwang, Yen-Hsu Chen, Horn-Che Chiang, Ming-Shyan Huang, Tyen-Po Chen
A nosocomial outbreak of Mycobacterium tuberculosis Beijing/W genotype infected 15 healthcare workers (HCWs) in a medical center in Taiwan, where there is a high prevalence of tuberculosis and a high rate of positive tuberculin skin tests. An index patient with laryngeal cancer and a lung abscess was identified by epidemiological investigation and it was found that an M. tuberculosis isolate from his lung tissue sample had an identical IS6110 restriction fragment length polymorphism pattern to the isolates from 3 HCWs...
May 2010: Japanese Journal of Infectious Diseases
Yvette E Smulders, Bert-Jan De Bondt, Martin Lacko, Janice Al Hodge, Kenneth W Kross
INTRODUCTION: Laryngeal tuberculosis used to be a common complication in advanced pulmonary tuberculosis. However, it has become a rare occurrence in developed countries since the introduction of antituberculous agents. Moreover, the pattern of the disease has changed over the years. Nowadays, it more closely resembles a laryngeal carcinoma than any other laryngeal illness. CASE PRESENTATION: We describe the case of a 50-year-old Caucasian man who presented with the clinical picture of laryngeal cancer, but which turned out to be tuberculosis...
2009: Journal of Medical Case Reports
S Al-Zahid, V Singh
OBJECTIVE: We report an extremely rare presentation of concomitant tuberculous cervical lymphadenitis in a patient with carcinoma of the larynx. CASE REPORT: A 66-year-old man presented with a nine-month history of hoarseness. He was found to have an exophytic lesion over the posterior half of the right vocal fold. He also had a palpable right jugulodigastric node. Biopsy of the vocal fold lesion revealed invasive squamous cell carcinoma. Histological analysis of an excision biopsy specimen from the lymph node was highly suggestive of tuberculosis...
January 2010: Journal of Laryngology and Otology
Fernando Pochini Sobrinho, Marinella Della Negra, Wladimir Queiroz, Ulisses José Ribeiro, Sérgio Bittencourt, Giselle Burlamaqui Klautau
The incidence of laryngeal histoplasmosis is low when compared to the total number of cases. Less than 100 cases of laryngeal histoplasmosis have been described in the medical literature. Isolated laryngeal involvement may lead to the misdiagnosis and mistreatment of tuberculosis or laryngeal cancer, according to some reports. The development of hoarseness in a patient with histoplasmosis or a laryngeal mass leading to hoarseness, might be suggestive of laryngeal histoplasmosis. When histoplasmosis is included among the differential diagnoses of a laryngeal lesion, the biopsy should be limited to a small tissue fragment, enough to perform histological tests...
November 2007: Brazilian Journal of Otorhinolaryngology
Chen-Chi Wang, Chang-Chun Lin, Ching-Ping Wang, Shih-An Liu, Rong-San Jiang
OBJECTIVES: To review the clinical characteristics of laryngeal tuberculosis. STUDY DESIGN: Retrospective case series. SUBJECTS AND METHODS: Medical records of 26 histopathology-confirmed cases in a tertiary medical center from 1992 to 2006. RESULTS: The female patients were significantly younger than male patients. Hoarseness is the most common symptom (84.6%) because true vocal fold is most commonly involved (80.8%)...
October 2007: Otolaryngology—Head and Neck Surgery
Dan-Hui Liu, Xiao-Min Wang, Li-Juan Zhang, Song-Wei Dai, Li-Yun Liu, Ji-Fu Liu, Shan-Shan Wu, Shuan-Ying Yang, Sam Fu, Xue-Yuan Xiao, Da-Cheng He
OBJECTIVE: To identify serum diagnosis or progression biomarkers in patients with lung cancer using protein chip profiling analysis. METHOD: Profiling analysis was performed on 450 sera collected from 213 patients with lung cancer, 19 with pneumonia, 16 with pulmonary tuberculosis, 65 with laryngeal carcinoma, 55 with laryngopharyngeal carcinoma patients, and 82 normal individuals. A new strategy was developed to identify the biomarkers on chip by trypsin pre-digestion...
February 2007: Biomedical and Environmental Sciences: BES
M Keberle, S Robinson
The aim was to give a systematic presentation of physiologic and pathologic calcifications and ossifications in the face and neck with a special emphasis on clinical relevance. In a sometimes subacute setting one should recognize specific calcifications which often lead to important diagnoses such as fungal sinusitis or sclerosing labyrinthitis. In a more chronic situation intraocular calcifications in small children are pathognomonic for retinoblastoma. Juxtatumoral sclerosis of the laryngeal cartilage in laryngopharyngeal carcinoma is usually caused by tumor infiltration of the cartilage resulting in a higher tumor stage and, this way, has a major impact on the therapeutical strategy...
August 2007: European Radiology
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