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https://www.readbyqxmd.com/read/28185166/paclitaxel-coated-balloon-for-femoropopliteal-artery-disease
#1
REVIEW
Saurabh Mehrotra, Ganesh Paramasivam, Sundeep Mishra
PURPOSE OF THE REVIEW: Percutaneous transluminal angioplasty is an established form of therapy for femoropopliteal artery disease. Currently, percutaneous transluminal angioplasty (PTA) is carried out using standard balloon with or without deployment of a stent but is associated with a high rate of restenosis and stent-related complications. Treatment options for restenosis, especially in-stent restenosis, are limited. Drug-coated balloons promise to reduce the rates of restenosis by effective delivery of antiproliferative agent (paclitaxel) directly to vessel wall without the need for a permanent implant...
February 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28169215/drug-coated-balloon-angioplasty-for-in-stent-restenosis-of-femoropopliteal-arteries-a-meta-analysis
#2
Salvatore Cassese, Gjin Ndrepepa, Sebastian Kufner, Robert A Byrne, Daniele Giacoppo, Ilka Ott, Karl-Ludwig Laugwitz, Heribert Schunkert, Adnan Kastrati, Massimiliano Fusaro
AIMS: To perform a meta-analysis investigating the outcomes of patients undergoing percutaneous revascularization with drug-coated balloon (DCB) angioplasty because of femoropopliteal in-stent restenosis (ISR). METHODS AND RESULTS: We searched scientific databases for studies of DCB angioplasty for femoropopliteal ISR. The primary outcome was target lesion revascularization (TLR). The main secondary outcome was recurrent ISR. Other outcomes of interest were Rutherford class (RC) improvement, ankle-brachial index (ABI) and death...
February 7, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28162988/drug-coated-balloon-angioplasty-for-subclavian-artery-stenosis-a-potential-novel-indication
#3
Derar Albashaireh, Georges Khoueiry, Owen Mogabgab, Qusay Saleh, Michael Foster, Nidal Abi Rafeh
Subclavian artery stenosis is associated with increased cardiovascular disease mortality. It remains an important treatable cause of upper extremity, brain and cardiac ischemia. Endovascular treatment with angioplasty and stenting has become the preferred modality of treatment. Surgical revascularization is reserved for difficult cases with unfavorable anatomy to endovascular approach. Here we describe a case of subclavian artery stenosis causing subclavian steal syndrome with unfavorable anatomy to stenting treated successfully with drug coated balloon angioplasty with maintenance of patency at 6months...
January 23, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28134126/changes-in-high-sensitivity-troponin-after-drug-coated-balloon-angioplasty-for-drug-eluting-stent-restenosis
#4
Roisin Colleran, Yukinora Harada, Sebastian Kufner, Daniele Giacoppo, Michael Joner, Salvatore Cassese, Tareq Ibrahim, Karl-Ludwig Laugwitz, Adnan Kastrati, Robert A Byrne
AIMS: Success of drug-coated balloon therapy might be compromised by intraprocedural particulate embolization of matrix coating, which may cause downstream microvascular obstruction. We aimed to investigate whether drug-coated balloon therapy was associated with an increase in markers of myocardial necrosis compared with drug-eluting stents or plain balloon angioplasty. METHODS AND RESULTS: In the ISAR DESIRE 3 trial, patients with limus-eluting stent restenosis were randomized to treatment with a paclitaxel-coated balloon (PCB), paclitaxel-eluting stent (PES) or balloon angioplasty (BA)...
January 31, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28133467/application-of-drug-coated-balloon-in-coronary-artery-intervention-challenges-and-opportunities
#5
REVIEW
Lei Gao, Yun-Dai Chen
In recent decades, the outcomes of coronary heart disease (CHD) have markedly improved, which can be partly attributed to the use of novel drugs (especially statins and antiplatelet drugs) and partly to the evolution of percutaneous coronary intervention (PCI). From percutaneous transluminal coronary angioplasty to bare-metal stent and then to drug-eluting stent, every step of PCI is attractive to interventional cardiologist, great progress has been made for patients with CHD. In the past few years, some successor devices for treating CHD have emerged...
November 2016: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/28126182/paclitaxel-coated-balloon-reduces-target-lesion-revascularization-compared-with-standard-balloon-angioplasty
#6
REVIEW
Nicholas Candy, Eugene Ng, Ramesh Velu
OBJECTIVE: Peripheral arterial disease (PAD) is a highly prevalent condition that contributes significantly to the morbidity and mortality of affected patients. PAD creates a significant economic burden on health care systems around the world. We reviewed all available literature to provide a meta-analysis assessing the outcome of patients treated with drug-eluting balloons (DEBs) compared with percutaneous transluminal balloon angioplasty (PTA) through measuring the rate of target lesion revascularization (TLR)...
February 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28116914/treatment-of-coronary-artery-in-stent-restenosis
#7
Damianos G Kokkinidis, Stephen W Waldo, Ehrin J Armstrong
Although drug-eluting stents (DES) have significantly reduced the incidence and prevalence of coronary in-stent restenosis (ISR), ISR still occurs in approximately 10% of patients in real-world practice. Areas covered: The development of newer generations of DES, drug-coated balloons (DCB) and increased use of intracoronary imaging have improved our treatment options for and pathophysiologic understanding of ISR. These technological advancements have also largely supplanted older modalities for treatment of ISR, such as brachytherapy, bare metal stents, conventional and cutting balloon angioplasty, and atherectomy devices...
January 31, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28116778/percutaneous-coronary-intervention-of-complex-calcified-lesions-with-drug-coated-balloon-after-rotational-atherectomy
#8
Tuomas T Rissanen, Sanna Uskela, Antti Siljander, Jussi M Kärkkäinen, Pirjo Mäntylä, Juha Mustonen, Jaakko Eränen
OBJECTIVES: We investigated the safety and efficacy of PCI using drug-coated balloon (DCB) after rotational atherectomy (rotablation) in a retrospective single center study in patients with calcified de novo coronary lesions. The majority of patients had an increased risk for bleeding. BACKGROUND: DCB has been effective in the treatment of in-stent restenosis, small vessels, and bifurcations. DCB enables short one month dual antiplatelet treatment. No published data exist on the use of DCB after rotablation...
January 23, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28111411/serial-observations-of-in-stent-restenosis-treated-with-drug-coated-balloon-angioplasty-by-optical-coherence-tomography-and-coronary-angioscopy
#9
Nobuhiro Murata, Tadateru Takayama, Takafumi Hiro
The drug-coated balloon (DCB) is a device that is used to reduce the risk of stent re-implantation in patients with in-stent restenosis (ISR). However, imaging findings of the drug covering the neointimal plaque immediately after treatment of ISR by DCB, and during follow-up, have only been discussed in a few reports. Herein, we describe the use of optical coherence tomography (OCT) and angioscopy to evaluate ISR before and after treatment with DCB, and during the follow-up period in 3 patients. The patients developed critical ISR during the follow-up period after drug-eluting stent (DES) implantation...
February 7, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28109036/a-propensity-score-matched-comparative-study-between-paclitaxel-coated-balloon-and-everolimus-eluting-stents-for-the-treatment-of-small-coronary-vessels
#10
Francesco Giannini, Azeem Latib, Marco B Ancona, Charis Costopoulos, Neil Ruparelia, Alberto Menozzi, Fausto Castriota, Antonio Micari, Alberto Cremonesi, Francesco De Felice, Alfredo Marchese, Maurizio Tespili, Patrizia Presbitero, Gregory A Sgueglia, Francesca Buffoli, Corrado Tamburino, Ferdinando Varbella, Antonio Colombo
OBJECTIVES: To compare the long-term clinical outcomes of paclitaxel drug-coated-balloons (DCB) and everolimus-eluting-stents (EES) following the treatment of de novo small vessel coronary artery disease. BACKGROUND: It is currently unclear whether treatment of de novo small vessel coronary disease with DCB is comparable to second generation drug-eluting stents, which are the current standard of care. METHODS: The present study enrolled 90 patients with small vessel coronary disease from the DCB treatment arm of the BELLO (Balloon Elution and Late Loss Optimization) trial and 2,000 patients treated with EES at the San Raffaele Scientific Institute...
January 21, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28089147/sequent-please-vs-pantera-lux-drug-coated-balloon-angioplasty-in-real-life-results-from-the-d%C3%A3-sseldorf-dcb-registry
#11
Athena Assadi-Schmidt, Annemarie Mohring, Eva Liebsch, Lisa Dannenberg, Alina Achilles, Martin Pöhl, Shazia Afzal, Verena Veulemans, Patrick Horn, Roberto Sansone, Florian Bönner, Bodo Levkau, Malte Kelm, Tobias Zeus, Amin Polzin
BACKGROUND: In-stent restenosis (ISR) is still a major concern in interventional cardiology. Drug coated balloon (DCB) angioplasty has been shown to be a promising option in treatment of ISR. However heterogeneity of different DCBs in suppression of neointimal growth has been described in a porcine model of coronary ISR. Therefore, in this registry analysis, we compared two frequently used paclitaxel eluting DCBs, the SeQuent Please and the Pantera Lux DCB. METHODS: 571 patients were treated with DCB angioplasty at the Heinrich-Heine University Düsseldorf between 2009 and 2012...
March 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28045341/acute-hypersensitivity-reaction-to-femoral-drug-coated-balloons
#12
Edward Lake, Michael Twigg, Finn Farquharson
We describe a case of an acute hypersensitivity reaction to a paclitaxel-coated balloon used in the peripheral arterial circulation. Clinicians using these products should be aware of this potential risk.
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January 3, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28038808/recurrent-in-stent-restenosis-certainty-of-its-origin-uncertainty-about-treatment
#13
REVIEW
Davide Piraino, Giuliana Cimino, Dario Buccheri, Gregory Dendramis, Giuseppe Andolina, Bernardo Cortese
Treatment of recurrent in-stent restenosis is a real brainteaser for the interventional cardiologist who cannot resort to the guidelines to have indications about the type of treatment to be preferred. The use of intracoronary imaging may provide insights into the underlying mechanisms of this complication and use of drug-coated balloons may be a valid alternative and especially a thoughtful treatment when the repeated and perseverant use of drug-eluting stents clearly fails. In this setting, we present a review of the literature about this interesting topic, going deep into the heart of the problem, its origin and possible treatment options...
March 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28008792/directional-atherectomy-with-antirestenotic-therapy-vs-drug-coated-balloon-angioplasty-alone-for-isolated-popliteal-artery-lesions
#14
Konstantinos Stavroulakis, Arne Schwindt, Giovanni Torsello, Arne Stachmann, Christiane Hericks, Michel J Bosiers, Efthymios Beropoulis, Stefan Stahlhoff, Theodosios Bisdas
PURPOSE: To report a single-center study comparing drug-coated balloon (DCB) angioplasty vs directional atherectomy with antirestenotic therapy (DAART) for isolated lesions of the popliteal artery. METHODS: Seventy-two patients were treated with either DCB angioplasty alone (n=31) or with DAART (n=41) for isolated popliteal artery stenotic disease between October 2009 and December 2015. The majority of patients presented with lifestyle-limiting claudication (74% vs 86%, respectively)...
December 1, 2016: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/27995490/hydrogel-tissue-expanders-for-stomatology-part-i-methacrylate-based-polymers
#15
Jakub Hrib, Jakub Sirc, Petr Lesny, Radka Hobzova, Miroslava Duskova-Smrckova, Jiri Michalek, Roman Smucler
In order to create a soft tissue surplus, implantable volume expanders are often utilized in dental surgery. Implanted tissue expanders should gradually increase their volume, exerting a constant pressure on the surrounding tissue for weeks. Current tissue expanders are based predominantly on externally inflatable balloons or on osmotically active tissue expanders that use soft hydrogels wrapped in perforated plastic coatings, which limit fluid entry and swelling. We have designed and examined tissue expanders based on the controlled rate expansive hydrogels synthesized from copolymers of selected methacrylates and N-vinylpyrrolidone, cross-linked with a combination of non-degradable (glycol dimethacrylates) and hydrolytically degradable (N,O-dimethacryloylhydroxylamine) cross-linkers...
January 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/27973329/a-novel-constrained-paclitaxel-coated-angioplasty-balloon-catheter
#16
Bodo Cremers, Gary Binyamin, Yvonne P Clever, Paul Seifert, Eitan Konstantino, Bettina Kelsch, Stephanie Bienek, Ulrich Speck, Bruno Scheller
AIMS: The study assessed drug adherence, transfer to the vessel wall, tolerance and efficacy of a constrained angioplasty balloon (Chocolate™) coated with an excipient enhanced paclitaxel coating (CCB) in the porcine model. METHODS AND RESULTS: Drug adherence was investigated in vitro. Drug transfer was evaluated in porcine arteries. A stent overstretch model was chosen to provoke intimal thickening in the efficacy and tolerance study. Conventional uncoated balloons were used as controls...
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27970235/tct-843-preclinical-evaluation-of-the-selution%C3%A2-sirolimus-drug-coated-balloon-in-a-porcine-coronary-overstretch-model
#17
John Elicker, Susanne Meis, John Shulze, Mike Ahlering, Scott Barnhill, Ronald Yamamoto, Jurjen Zoethout
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970199/tct-809-stenting-for-the-treatment-of-pulmonary-vein-stenosis-after-atrial-fibrillation-radiofrequency-catheter-ablation-initial-experience-with-peripheral-stents-plus-drug-coated-balloons-and-coronary-drug-eluting-stents
#18
Guido Ghirardi, Cristina Ferrari, Gianluca Pontone, Daniela Trabattoni, Claudio Tondo, Franco Fabbiocchi, Piero Montorsi, Alessandro Lualdi, Antonio Bartorelli
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970162/tct-776-vascular-healing-response-after-implantation-of-a-novel-fluoropolymer-coated-paclitaxel-eluting-peripheral-stent-a-comparative-drug-eluting-stent-study-in-a-familial-hypercholesterolemic-swine-model-of-balloon-injured-femoral-arteries
#19
Pawel Gasior, Yanping Cheng, Andres Valencia, Jenn McGregor, Gerard Conditt, Juan Granada
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970161/tct-775-results-of-the-first-in-human-chocolate-touch-drug-coated-balloon-catheter-endure-trial
#20
Mehdi Shishehbor, Thomas Zeller, Andrew Holden
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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