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https://www.readbyqxmd.com/read/29131504/balloon-pin-hole-rupture-during-percutaneous-coronary-intervention-for-recurrent-calcified-in-stent-restenosis-a-case-report
#1
Nobuhiro Murata, Tadateru Takayama, Takafumi Hiro, Atsushi Hirayama
Percutaneous coronary intervention (PCI) for patients with in-stent restenosis (ISR) is generally considered safe and effective. However, due to increased tissue hardness, PCI for calcified intra-stent ISR is technically challenging. Here, we report severe angioplasty-related complications in a patient presenting with calcified, recurrent ISR following PCI. After receiving drug-coated balloon (DCB) angioplasty for an initial ISR, the patient developed recurrent ISR during the follow-up period. Intravascular imaging revealed intra-stent calcifications and balloon angioplasty was subsequently performed...
November 13, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29125264/drug-coated-balloons-reduce-the-risk-of-recurrent-restenosis-in-arteriovenous-fistulas-and-prosthetic-grafts-for-hemodialysis
#2
Nicola Troisi, Pierfrancesco Frosini, Chiara Somma, Eugenio Romano, Azzurra Guidotti, Pietro C Dattolo, Giuseppe Ferro, Emiliano Chisci, Stefano Michelagnoli
BACKGROUND: Aim of this study was to evaluate the early and mid-term outcomes of drug-coated balloons (DCBs) in hemodialysis patients with recurrent stenosis of arteriovenous fistula and previously treated with plain balloon angioplasty (PBA). METHODS: Between July 2013 and June 2016 38 hemodialysis patients with recurrent stenosis of arteriovenous fistula underwent endovascular treatment with a DCB at our center. All patients were previously treated at the target lesion with a PBA...
November 10, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29078242/-drug-coated-balloon-angioplasty-in-femoropopliteal-arteries-is-there-a-class-effect
#3
Ulf Karl-Martin Teichgräber, Christof Klumb
Aim Percutaneous transluminal angioplasty (PTA) is a well-accepted method to re-establish patency in stenotic and reoccluded vessels. One tool to improve results may be to use paclitaxel drug-coated balloon (DCB) catheters. This systematic review investigates whether there is a class effect among different DCBs. Methods The primary endpoint was "Freedom from Target Lesion Revascularisation" (FfTLR) after 12 months. A systematic literature search was performed in PubMed and risk of bias was assessed of the included trials...
October 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29050631/drug-coated-balloon-treatment-for-femoropopliteal-artery-disease-the-in-pact-global-study-de-novo-in-stent-restenosis-imaging%C3%A2-cohort
#4
Marianne Brodmann, Koen Keirse, Dierk Scheinert, Lubomir Spak, Michael R Jaff, Randy Schmahl, Pei Li, Thomas Zeller
OBJECTIVES: This study sought to evaluate the safety and effectiveness of a paclitaxel-coated drug-coated balloon (DCB) for the treatment of patients with de novo in-stent restenosis (ISR). BACKGROUND: Treatment of patients with ISR remains a challenge. Current strategies are plagued by high rates of recurrent restenosis and need for reintervention. The best intervention for ISR remains to be elucidated. METHODS: The IN.PACT Global study is an independently adjudicated multicenter, prospective, single-arm study that enrolled 1,535 subjects with symptomatic atherosclerotic disease of the superficial femoral and/or popliteal arteries, including de novo ISR lesions...
October 23, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29031986/endovascular-interventions-for-femoropopliteal-peripheral-artery-disease-a-network-meta-analysis-of-current-technologies
#5
REVIEW
Michael R Jaff, Teresa Nelson, Nicole Ferko, Melissa Martinson, Louise H Anderson, Sarah Hollmann
PURPOSE: To use network meta-analysis (NMA) to determine the optimal endovascular strategy for management of femoropopliteal peripheral artery disease (PAD) given the lack of multiple prospective randomized trials to guide treatment decisions. MATERIALS AND METHODS: NMA is a new meta-analytic method that permits comparisons among any 2 therapies by combining results of a collection of clinical trials conducted in the same or similar patient population. NMA was used to analyze data from 15 randomized controlled trials (RCTs) and 10 prospective, multicenter, single-arm trials (combined evidence [CE] NMA) that evaluated target lesion revascularization (TLR) for 5 endovascular strategies: bare metal stent (BMS), polymer-covered metal stent (CMS), drug-eluting stent (DES), drug-coated balloon (DCB) and percutaneous transluminal angioplasty (PTA)...
October 12, 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29027735/temporal-trends-in-percutaneous-coronary-interventions-thru-the-drug-eluting-stent-era-insights-from-18-641-procedures-performed-over-12-year-period
#6
Uri Landes, Tamir Bental, Amos Levi, Abid Assali, Hana Vaknin-Assa, Eli I Lev, Eldad Rechavia, Gabriel Greenberg, Katia Orvin, Ran Kornowski
BACKGROUND: The last decade, regarded as the DES era in PCI, has witnessed significant advances in the management of coronary disease. We aimed to assess temporal trends in the practice and outcome of percutaneous coronary intervention (PCI) during the drug eluting stent (DES) era. METHODS: We analyzed 18,641 consecutive PCI's performed between January 2004 and December 2016, distinguished by procedural date (Q1 : 2004-2006, n = 4,865; Q2 : 2007-2009, n = 4,977; Q3 : 2010-2012, n = 4,230; Q4 : 2013-2016, n = 4,569)...
October 13, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29024274/second-generation-drug-eluting-stents-versus-drug-coated-balloons-for-the-treatment-of-coronary-in-stent-restenosis-a-systematic-review-and-meta-analysis
#7
Damianos G Kokkinidis, Andrew F Prouse, Seth J Avner, Joo Myung Lee, Stephen W Waldo, Ehrin J Armstrong
PURPOSE: The benefit of drug-eluting stents (DES) versus drug-coated balloons (DCB) in coronary artery in-stent restenosis (ISR) for the prevention of target lesion revascularization (TLR), stent thrombosis, and mortality remains uncertain. Our aim was to synthesize the available evidence from randomized clinical trials (RCTs) and observational studies that directly compare second-generation drug-eluting stents (SG-DES) and DCB for the treatment of coronary ISR. METHODS: Medline, Embase, and Cochrane Central were searched for RCTs or observational studies, published up to March 15, 2017...
October 10, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28980462/treatment-of-femoropopliteal-atherosclerotic-lesions-using-the-ranger-paclitaxel-coated-balloon-catheter-12-month-results-from-an-all-comers-registry
#8
Michael Lichtenberg, Peter von Bilderling, Jürgen Ranft, Kathrin Niemöller, Holger Grell, Lucas Briner, Françoise Saucy, Tienush Rassaf, Frank Breuckmann
BACKGROUND: To evaluate 12-month effectiveness of the endovascular treatment of femoropopliteal (FP) atherosclerotic lesions with the Ranger drug-coated balloon (DCB) in a real-world setting. METHODS: In this prospective, observational, multicenter trial (ClinicalTrials.gov Identifier: NCT02462005) 172 consecutive patients with 226 de novo, restenosed, or reoccluded native superficial femoral and/or popliteal artery lesions were treated with the Ranger paclitaxel- coated balloon angioplasty...
October 3, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28975778/debulking-plus-drug-coated-balloon-combination-as-revascularization-strategy-for-complex-femoropopliteal-lesions
#9
Katia Dessi, Luca Giovannacci, Jos C Vand den Berg
This paper will discuss the results from the most recent randomized trials and large registries for DCB's and atherectomy, and the drawbacks of these 2 therapeutic options. It will also discuss the results of combination therapy in complex femoropopliteal lesions. Several studies indicate that combining atherectomy and DCB yields better outcomes in complex calcified lesions, but the only randomized pilot study could not demonstrate a benefit of combination therapy in the mid-term follow-up. Larger, randomized studies are needed to define the role of atherectomy followed by DCB angioplasty further...
October 2, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28975777/the-evolving-role-of-drug-coated-balloons-for-the-treatment-of-complex-femoropopliteal-lesions
#10
Grigorios Korosoglou, Michael Lichtenberg, Sultan Celik, Joachim Andrassy, Marianne Brodmann, Martin Andrassy
INTRODUCTION: Conventional therapies for transcatheter treatment of patients with infrainguinal obstructive disease remain compromised by high restenosis rates. Drug-coated balloons (DCB) offer a novel therapeutic alternative targeting the source of neo-intimal hyperplasia, without the need for a permanent endovascular scaffold and their inherent limitations. EVIDENCE ACQUISITION: A systematic research of the medical databases (Pubmed) has been conducted for this up-to-date review...
October 2, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28966454/endovascular-therapy-of-axillary-artery-disease-with-drug-coated-balloon-angioplasty
#11
Subhi J Al'Aref, Rajesh V Swaminathan, Dmitriy N Feldman
The occurrence of upper-extremity arterial disease is less common than that of the lower extremities. Nevertheless, exercise-induced symptoms, when present, can significantly affect functional capacity and limit quality of life. We report a case of exertional right upper-extremity pain and severe right axillary artery disease that was revascularized using an off-label drug-coated balloon technology with resolution of symptoms.
October 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28966325/rotational-atherectomy-followed-by-drug-coated-balloon-dilation-for-left-main-in-stent-restenosis-in-the-setting-of-acute-coronary-syndrome-complicated-with-right-coronary-chronic-total-occlusion
#12
Jun Shiraishi, Keisuke Shoji, Takashi Yanagiuchi, Masaki Yashige, Akira Shikuma, Daisuke Ito, Masayoshi Kimura, Eigo Kishita, Yusuke Nakagawa, Masayuki Hyogo, Takahisa Sawada
An 83-year-old man presented with recurrent acute coronary syndrome (ACS) at the left main coronary artery (LMCA) complicated with ostial chronic total occlusion (CTO) in the right coronary artery (RCA) (RCA-CTO). At the first LMCA-ACS approximately 1 year earlier, he had undergone LMCA-crossover stenting with a biolimus-eluting stent in the presence of RCA-CTO. At the second LMCA-ACS, we angiographically confirmed severe in-stent restenosis in the distal LMCA, in addition to angled severe stenosis in the just proximal LCx, and performed primary PCI for the LMCA bifurcation lesion under intra-aortic balloon pumping support...
October 21, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28965230/optical-frequency-domain-imaging-guided-rotational-atherectomy-followed-by-drug-coated-balloon-dilation-to-the-non-calcified-lesion-in-a-patient-with-severe-thrombocytopenia
#13
Jun Shiraishi, Muneo Ohshiro, Yuki Matsubara, Masayuki Hyogo, Hitoji Uchiyama, Takahisa Sawada
No abstract text is available yet for this article.
September 30, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28964764/the-sabre-trial-sirolimus-angioplasty-balloon-for%C3%A2-coronary-in-stent-restenosis-angiographic-results-and-1-year-clinical-outcomes
#14
Stefan Verheye, Mathias Vrolix, Indulis Kumsars, Andrejs Erglis, Dace Sondore, Pierfrancesco Agostoni, Kristoff Cornelis, Luc Janssens, Michael Maeng, Ton Slagboom, Giovanni Amoroso, Lisette Okkels Jensen, Juan F Granada, Pieter Stella
OBJECTIVES: The aim of this first-in-human study was to assess the safety and effectiveness of the Virtue sirolimus-eluting balloon in a cohort of patients with in-stent restenosis (ISR). BACKGROUND: Angioplasty balloons coated with the cytotoxic drug paclitaxel have been widely used for ISR treatment. The Virtue angioplasty balloon (Caliber Therapeutics, New Hope, Pennsylvania) delivers sirolimus in a nanoencapsulated liquid formulation. This clinical trial is the first to examine a sirolimus-eluting balloon for ISR...
September 19, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28958476/cost-effectiveness-analysis-of-drug-coated-therapies-in-the-superficial-femoral-artery
#15
REVIEW
Natalie D Sridharan, Aureline Boitet, Kenneth Smith, Kathy Noorbakhsh, Efthymios Avgerinos, Mohammad H Eslami, Michel Makaroun, Rabih Chaer
OBJECTIVE: Drug-coated balloons (DCBs) may increase durability of endovascular treatment of superficial femoral artery (SFA) disease while avoiding stent-related risks. The purpose of this study was to use meta-analytic data of DCB studies to compare the cost-effectiveness of potential SFA treatments: DCB, drug-eluting stent (DES), plain old balloon angioplasty (POBA), or bare-metal stent (BMS). METHODS: A search for randomized controlled trials comparing DCB with POBA for treatment of SFA disease was performed...
September 25, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28933522/drug-coated-balloons-in-the-superficial-femoral-artery
#16
Oliver Schlager, Michael E Gschwandtner, Andrea Willfort-Ehringer, Florian Wolf, Christian Loewe, Renate Koppensteiner, Michael Lichtenberg
Despite the progress in endovascular treatment of patients with peripheral arterial disease, restenosis remains the major drawback, especially in patients with femoropopliteal lesions. To reduce neointimal proliferation and subsequent restenosis the use of antiproliferative drug eluting devices was implemented in the endovascular treatment of femoropopliteal disease. Aiming to use the favorable effects of these antiproliferative agents and to reduce foreign body exposure in affected arteries, drug coated balloons (DCB) have been developed...
September 20, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28923693/novel-paclitaxel-coated-scoring-ballon-for-de-novo-complex-coronary-lesions-first-report
#17
Gaetano di Palma, Bernardo Cortese
Drug-coated balloons (DCB) are being used for in-stent restenosis treatment and there is some preliminary experience in other coronary settings, including small vessels and side branches. Scoring balloons (SB) are a useful tool for the preparation of fibro-calcific lesions. Because of the controlled micro-dissections that SB induce, it has been hypothesized that they may have a role in helping paclitaxel deliverability inside the vessel wall. The AngioSculpt®X (Spectranetics) is a novel paclitaxel-coated SB with encouraging preliminary data for the treatment of in-stent restenosis...
August 12, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28916599/directional-atherectomy-followed-by-a-paclitaxel-coated-balloon-to-inhibit-restenosis-and-maintain-vessel-patency-twelve-month-results-of-the-definitive-ar-study
#18
Thomas Zeller, Ralf Langhoff, Krishna J Rocha-Singh, Michael R Jaff, Erwin Blessing, Beatrice Amann-Vesti, Marek Krzanowski, Patrick Peeters, Dierk Scheinert, Giovanni Torsello, Sebastian Sixt, Gunnar Tepe
BACKGROUND: Studies assessing drug-coated balloons (DCB) for the treatment of femoropopliteal artery disease are encouraging. However, challenging lesions, such as severely calcified, remain difficult to treat with DCB alone. Vessel preparation with directional atherectomy (DA) potentially improves outcomes of DCB. METHODS AND RESULTS: DEFINITIVE AR study (Directional Atherectomy Followed by a Paclitaxel-Coated Balloon to Inhibit Restenosis and Maintain Vessel Patency-A Pilot Study of Anti-Restenosis Treatment) was a multicenter randomized trial designed to estimate the effect of DA before DCB to facilitate the development of future end point-driven randomized studies...
September 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28916429/incidence-and-predictors-of-recurrent-restenosis-after-drug-coated-balloon-angioplasty-for-restenosis-of-a-drug-eluting-stent-the-icarus-cooperation
#19
Salvatore Cassese, Bo Xu, Seiji Habara, Harald Rittger, Robert A Byrne, Matthias Waliszewski, María José Pérez-Vizcayno, Runlin Gao, Adnan Kastrati, Fernando Alfonso
INTRODUCTION AND OBJECTIVES: The incidence and predictors of recurrent restenosis after drug-coated balloon (DCB) angioplasty for drug-eluting stent (DES) restenosis remain poorly studied. We sought to evaluate the incidence and predictors of recurrent restenosis among participants in randomized controlled trials receiving DCB angioplasty for DES restenosis. METHODS: The clinical and lesion data of individuals enrolled in 6 randomized controlled trials of DCB angioplasty for DES restenosis were pooled...
September 12, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28902718/effect-of-drug-coated-balloon-on-stent-restenosis-neointimal-proliferation-and-coronary-dissection-an-optical-coherence-tomography-analysis
#20
Taku Fukushima, Takashi Ashikaga, Shunji Yoshikawa, Yu Hatano, Daisuke Ueshima, Takanobu Yamamoto, Maejima Yasuhiro, Mitsuaki Isobe
AIM: The aim of this study was to assess the acute and mid-term effects of drug-coated balloon (DCB) in terms of the healing process of non-flow-limiting dissections and changes in the neointimal area after DCB treatment using frequency domain optical coherence tomography (FD-OCT). PATIENTS AND METHODS: Thirty-six consecutive patients with in-stent restenosis pretreated with a scoring balloon were evaluated (19 and 17 patients with and without a DCB, respectively)...
September 11, 2017: Coronary Artery Disease
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