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https://www.readbyqxmd.com/read/29340312/ckd-screening-and-surveillance-in-australia-past-present-and-future
#1
REVIEW
Sree K Venuthurupalli, Wendy E Hoy, Helen G Healy, Anne Cameron, Robert G Fassett
Chronic kidney disease (CKD) was largely a hidden health problem until the publication of an internationally agreed approach to its identification, monitoring, and treatment. The 2002 National Kidney Foundation CKD classification and the subsequent 2006 Kidney Disease Improving Global Outcomes (KDIGO) recommendations are powerful tools for translating thinking about CKD into clinical practice. These guidelines were strongly endorsed by the international community, including Australia, and were incorporated into CKD practice guidelines...
January 2018: KI Reports
https://www.readbyqxmd.com/read/29321053/data-sharing-in-clinical-trials-practical-guidance-on-anonymising-trial-datasets
#2
Catriona Keerie, Christopher Tuck, Garry Milne, Sandra Eldridge, Neil Wright, Steff C Lewis
BACKGROUND: There is an increasing demand by non-commercial funders that trialists should provide access to trial data once the primary analysis is completed. This has to take into account concerns about identifying individual trial participants, and the legal and regulatory requirements. METHODS: Using the good practice guideline laid out by the work funded by the Medical Research Council Hubs for Trials Methodology Research (MRC HTMR), we anonymised a dataset from a recently completed trial...
January 10, 2018: Trials
https://www.readbyqxmd.com/read/29309595/clinical-diabetes-centers-of-excellence-a-model-for-future-adult-diabetes-care
#3
Boris Draznin, Peter A Kahn, Nicole Wagner, Irl B Hirsch, Mary Korytkowski, David M Harlan, Marie E McDonnell, Robert A Gabbay
While diabetes research centers are well defined by National Institutes of Health, there is no clear definition for clinical Diabetes Centers of Excellence (DCOE). There are multiple clinical diabetes centers across the US, some established with philanthropic funding; however, it is not clear what defines a DCOE from a clinical perspective and what the future will be for these centers.In this Perspective we propose a framework to guide advancement for DCOE. With the shift toward value-based purchasing and reimbursement and away from fee for service, defining the procedures for broader implementation of DCOE as a way of improving population health, patient care experience (including quality and satisfaction), and reducing healthcare costs becomes critically important...
January 4, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29296132/proceedings-of-the-canadian-frailty-network-summit-medication-optimization-for-frail-older-canadians-toronto-monday-april-24-2017
#4
John Muscedere, Perry Kim, Peter Aitken, Michael Gaucher, Robin Osborn, Barbara Farrell, Jayna Holroyd-Leduc, Laurie Mallery, Henry Siu, James Downar, Todd C Lee, Emily McDonald, Lisa Burry
Appropriate and optimal use of medication and polypharmacy are especially relevant to the care of older Canadians living with frailty, often impacting their health outcomes and quality of life. A majority (two thirds) of older adults (65 or older) are prescribed five or more drug classes and over one-quarter are prescribed 10 or more drugs. The risk of adverse drug-induced events is even greater for those aged 85 or older where 40% are estimated to take drugs from 10 or more drug classes. The Canadian Frailty Network (CFN), a pan-Canadian non-for-profit organization funded by the Government of Canada through the Networks of Centres of Excellence Program (NCE), is dedicated to improving the care of older Canadian living with frailty and, as part of its mandate, convened a meeting of stakeholders from across Canada to seek their perspectives on appropriate medication prescription...
December 2017: Canadian Geriatrics Journal: CGJ
https://www.readbyqxmd.com/read/29290168/the-economic-burden-of-acpa-positive-status-among-patients-with-rheumatoid-arthritis
#5
Jason Shafrin, Mahlet Gizaw Tebeka, Kwanza Price, Chad Patel, Kaleb Michaud
BACKGROUND: Anticitrullinated protein antibodies (ACPAs) are serological biomarkers associated with early, rapidly progressing rheumatoid arthritis (RA), including more severe disease and joint damage. ACPA testing has become a routine tool for RA diagnosis and prognosis. Furthermore, treatment efficacy has been shown to vary by ACPA-positive status. However, it is not clear if the economic burden of patients with RA varies by ACPA status. OBJECTIVE: To determine if the economic burden of RA varies by patient ACPA status...
January 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29233795/using-microsimulation-to-estimate-the-future-health-and-economic-costs-of-salmonellosis-under-climate-change-in-central-queensland-australia
#6
Dimity Maree Stephen, Adrian Gerard Barnett
BACKGROUND: The incidence of salmonellosis, a costly foodborne disease, is rising in Australia. Salmonellosis increases during high temperatures and rainfall, and future incidence is likely to rise under climate change. Allocating funding to preventative strategies would be best informed by accurate estimates of salmonellosis costs under climate change and by knowing which population subgroups will be most affected. OBJECTIVE: We used microsimulation models to estimate the health and economic costs of salmonellosis in Central Queensland under climate change between 2016 and 2036 to inform preventative strategies...
December 11, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29221624/international-medical-graduates-in-nephrology-roles-rules-and-future-risks
#7
Jeffrey S Berns, Muriel Ghosn, Rodolfo R Altamirano
International medical graduates (IMGs) have become an increasingly essential part of many residency and fellowship programs in the United States. IMGs, who may be of either US or non-US citizenship, contribute significantly to the physician workforce across this country, particularly in underserved areas, as well as in their home countries on their return after training. Approximately 65% of nephrology fellows are IMGs, with most of these being non-US citizens. Non-US IMG applications for nephrology fellowship have been declining, exacerbating an ongoing shortage of nephrology trainees...
December 5, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29216896/what-will-it-take-pathways-time-and-funding-australian-medical-students-perspective-on-clinician-scientist-training
#8
Diann S Eley, Charmaine Jensen, Ranjeny Thomas, Helen Benham
BACKGROUND: Clinician-scientists are in decline worldwide. They represent a unique niche in medicine by bridging the gap between scientific discovery and patient care. A national, integrated approach to training clinician-scientists, typically programs that comprise a comprehensive MD-PhD pathway, are customary. Such a pathway is lacking in Australia. The objective was to gather perceptions from Australian medical students on factors they perceive would influence their decision to pursue clinician-scientist training...
December 8, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29212477/nurse-health-and-lifestyle-modification-versus-standard-care-in-40-to-70-year-old-regional-adults-study-protocol-of-the-management-to-optimise-diabetes-and-metabolic-syndrome-risk-reduction-via-nurse-led-intervention-modern-randomized-controlled-trial
#9
Melinda J Carrington, Paul Zimmet
BACKGROUND: Metabolic syndrome (MetS), the clustering of multiple leading risk factors, predisposes individuals to increased risk for developing type 2 diabetes and/or cardiovascular disease (CVD). Cardio-metabolic disease risk increases with greater remoteness where specialist services are scarce. Nurse-led interventions are effective for the management of chronic disease. The aim of this clinical trial is to determine whether a nurse-implemented health and lifestyle modification program is more beneficial than standard care to reduce cardio-metabolic abnormalities and future risk of CVD and diabetes in individuals with MetS...
December 6, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29202782/studying-de-implementation-in-health-an-analysis-of-funded-research-grants
#10
Wynne E Norton, Amy E Kennedy, David A Chambers
BACKGROUND: Studying de-implementation-defined herein as reducing or stopping the use of a health service or practice provided to patients by healthcare practitioners and systems-has gained traction in recent years. De-implementing ineffective, unproven, harmful, overused, inappropriate, and/or low-value health services and practices is important for mitigating patient harm, improving processes of care, and reducing healthcare costs. A better understanding of the state-of-the-science is needed to guide future objectives and funding initiatives...
December 4, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29198877/the-future-role-of-the-united-states-in-global-health-emphasis-on-cardiovascular-disease
#11
REVIEW
Valentin Fuster, Jendayi Frazer, Megan Snair, Rajesh Vedanthan, Victor Dzau
U.S. global health investment has focused on detection, treatment, and eradication of infectious diseases such as tuberculosis, malaria, and human immunodeficiency virus/acquired immunodeficiency syndrome, with significant results. Although efforts should be maintained and expanded to provide ongoing therapy for chronic infectious disease, there is a pressing need to meet the challenge of noncommunicable diseases, which constitute the highest burden of diseases globally. A Committee of the National Academies of Sciences, Engineering, and Medicine has made 14 recommendations that require ongoing commitments to eradication of infectious disease and increase the emphasis on chronic diseases such as cardiovascular disease...
November 23, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29175882/evidence-and-speculation-reimagining-approaches-to-architecture-and-research-within-the-paediatric-hospital
#12
Rebecca McLaughlan, Alan Pert
As the dominant research paradigm within the construction of contemporary healthcare facilities, evidence-based design (EBD) will increasingly impact our expectations of what hospital architecture should be. Research methods within EBD focus on prototyping incremental advances and evaluating what has already been built. Yet medical care is a rapidly evolving system; changes to technology, workforce composition, patient demographics and funding models can create rapid and unpredictable changes to medical practice and modes of care...
November 25, 2017: Medical Humanities
https://www.readbyqxmd.com/read/29172220/-strengthening-public-health-by-strengthening-public-health-research-results-of-the-working-group-7-of-the-forum-future-public-health-berlin-2016
#13
Bärbel Maria Kurth, Tobias Kurth
Public health research is application-oriented, its great potential lies in the interlinking of science and practice, as well as its interdisciplinarity and methodological competence. Public health research is focused on the development and evaluation of measures to protect and improve the health of the population. In doing so, it must make its contribution to tackling the new challenges posed by demographic change, digitalization, new forms of communication and medical progress. By pooling the forces, the public health scientists should actively contribute to policy advice and promoting adequate research funding...
November 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29171379/collaborative-care-for-screen-positive-elders-with-major-depression-casper-plus-a-multicentred-randomised-controlled-trial-of-clinical-effectiveness-and-cost-effectiveness
#14
Katharine Bosanquet, Joy Adamson, Katie Atherton, Della Bailey, Catherine Baxter, Jules Beresford-Dent, Jacqueline Birtwistle, Carolyn Chew-Graham, Emily Clare, Jaime Delgadillo, David Ekers, Deborah Foster, Rhian Gabe, Samantha Gascoyne, Lesley Haley, Jahnese Hamilton, Rebecca Hargate, Catherine Hewitt, John Holmes, Ada Keding, Helen Lewis, Dean McMillan, Shaista Meer, Natasha Mitchell, Sarah Nutbrown, Karen Overend, Steve Parrott, Jodi Pervin, David A Richards, Karen Spilsbury, David Torgerson, Gemma Traviss-Turner, Dominic Trépel, Rebecca Woodhouse, Simon Gilbody
BACKGROUND: Depression in older adults is common and is associated with poor quality of life, increased morbidity and early mortality, and increased health and social care use. Collaborative care, a low-intensity intervention for depression that is shown to be effective in working-age adults, has not yet been evaluated in older people with depression who are managed in UK primary care. The CollAborative care for Screen-Positive EldeRs (CASPER) plus trial fills the evidence gap identified by the most recent guidelines on depression management...
November 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/29168653/utilizing-biomarkers-in-colorectal-cancer-an-interview-with-ajay-goel
#15
Ajay Goel
Ajay Goel, PhD, is a Professor and Director, Center for Gastrointestinal Research, and Director, Center for Translational Genomics and Oncology, at the Baylor Scott & White Research Institute, Baylor University Medical Center in Dallas, Texas. Dr Goel has spent more than 20 years researching cancer and has been the lead author or contributor to over 240 scientific articles published in peer-reviewed international journals and several book chapters. He is also a primary inventor on more than 15 international patents aimed at developing various biomarkers for the diagnosis, prognosis and prediction of gastrointestinal cancers...
November 23, 2017: Future Oncology
https://www.readbyqxmd.com/read/29157228/fellowship-training-a-qualitative-study-of-scope-and-purpose-across-one-department-of-medicine
#16
Jolanta Karpinski, Rola Ajjawi, Katherine Moreau
BACKGROUND: Fellowship training follows certification in a primary specialty or subspecialty and focusses on distinct and advanced clinical and/or academic skills. This phase of medical education is growing in prevalence, but has been an "invisible phase of postgraduate training" lacking standards for education and accreditation, as well as funding. We aimed to explore fellowship programs and examine the reasons to host and participate in fellowship training, seeking to inform the future development of fellowship education...
November 21, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29145728/understanding-how-emergency-medicine-physicians-survive-and-thrive-in-rural-practice-a-theoretical-model
#17
Ashra Kolhatkar, Andrea Keesey, Bob Bluman, Brenna Lynn, Tandi Wilkinson
INTRODUCTION: The challenges facing emergency medicine (EM) services in Canada reflect the limitations of the entire healthcare system. The emergency department (ED) is uniquely situated in the healthcare system such that shortcomings in hospital- and community-based services are often first revealed there. This is especially true in rural settings, where there are additional site-specific barriers to the provision of EM care. Existing studies look at the factors that influence rural EM physicians in isolation...
November 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/29101142/protocol-for-a-national-prevalence-study-of-advance-care-planning-documentation-and-self-reported-uptake-in-australia
#18
Rasa Ruseckaite, Karen M Detering, Sue M Evans, Veronica Perera, Lynne Walker, Craig Sinclair, Josephine M Clayton, Linda Nolte
INTRODUCTION: Advance care planning (ACP) is a process between a person, their family/carer(s) and healthcare providers that supports adults at any age or stage of health in understanding and sharing their personal values, life goals and preferences regarding future medical care. The Australian government funds a number of national initiatives aimed at increasing ACP uptake; however, there is currently no standardised Australian data on formal ACP documentation or self-reported uptake...
November 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29083975/factors-associated-with-direct-health-care-costs-among-patients-with-migraine
#19
Machaon Bonafede, Qian Cai, Katherine Cappell, Gilwan Kim, Sandhya J Sapra, Neel Shah, Katherine Widnell, Paul Winner, Pooja Desai
BACKGROUND: Migraine imposes substantial economic burden on patients and the health care system. Approximately 18% of women and 6% of men suffer from migraine in the United States. This is a heterogeneous group, and little data are available to evaluate factors associated with migraine costs. OBJECTIVE: To evaluate characteristics associated with high costs among commercially insured patients with migraine. METHODS: This retrospective analysis identified patients with migraine in the Truven Health MarketScan Research Databases between January 2008 and June 2013...
November 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29083966/opioid-abuse-a-detailed-examination-of-cost-drivers-over-a-24-month-follow-up-period
#20
Lauren M Scarpati, Noam Y Kirson, Zitong B Jia, Jody Wen, Jaren Howard
BACKGROUND: Previous work has documented the considerable economic burden associated with opioid abuse, dependence, and overdose/poisoning (hereafter, "abuse"). Recent analyses have provided insights into the trajectory and drivers of the excess costs of abuse both before and after diagnosis, showing the important role of other substance abuse, mental health issues, and painful conditions. OBJECTIVE: To build on the recently published study by Kirson et al. (2017) and extend its findings by (a) evaluating the trajectory of excess costs of abuse for an additional year after an incident abuse diagnosis and (b) exploring the diagnosis-level drivers of excess costs over time in greater detail...
November 2017: Journal of Managed Care & Specialty Pharmacy
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