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Silvia Cid-Juárez, Rogelio Pérez-Padilla, Luis Torre-Bouscoulet, Paul Enright, Laura Gochicoa-Rangel, Daniel Cortés-Medina, Peter Eliud Bapo-López, Marco Vinicio Tafolla-Manzo, Sergio Manuel Grave Díaz
BACKGROUND: Measured maximum voluntary ventilation (MVV) correlates with maximum ventilatory capacity during exercise. As a shortcut, MVV is often estimated by multiplying measured FEV1 times 35 or 40, but this index varies with altitude due to reduced air density. The objective was to describe MVV in healthy individuals residing at 2,240 m above sea level and compare it with the reference values customarily employed. METHODS: We recruited a convenience sample of respiratory-healthy, non-obese volunteers >10 y of age who had resided for >2 y in Mexico City...
August 22, 2017: Respiratory Care
Laura Gochicoa-Rangel, Rodrigo Del Río-Hidalgo, Juana Hernández-Ruiz, Luis Rodríguez-Moreno, David Martínez-Briseño, Uri Mora-Romero, Silvia Cid-Juárez, Cecilia García-Sancho, Luis Torre-Bouscoulet
BACKGROUND: The impulse oscillometry system (IOS) measures the impedance (Z) of the respiratory system, but proper interpretation of its results requires adequate reference values. The objectives of this work were: (1) to validate the reference equations for the IOS published previously by our group and (2) to compare the adjustment of new available reference equations for the IOS from different countries in a sample of healthy children. METHODS: Subjects were healthy 4-15-y-old children from the metropolitan area of Mexico City, who performed an IOS test...
September 2017: Respiratory Care
Selene Guerrero Zúñiga, Julia Sánchez Hernández, Heidegger Mateos Toledo, Mayra Mejía Ávila, Laura Gochicoa-Rangel, José Luis Miguel Reyes, Moisés Selman, Luis Torre-Bouscoulet
BACKGROUND AND OBJECTIVE: Lung biopsies from patients with hypersensitivity pneumonitis (HP) have demonstrated small airway (SA) involvement, but there is no information concerning SA function in HP, and it is unknown whether pharmacological treatment could modify its function. SA function in patients with chronic HP using ultrasonic pneumography (UPG) and impulse oscillometry (IOS) was explored. We also compared initial results with those obtained after 4 weeks of standardized treatment with azathioprine and prednisone...
November 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
Martín Becerril-Ángeles, Mario H Vargas, Leonardo Hernández-Pérez, Nancy Judith Rivera-Istepan, Rebeca Ivonne Pérez-Hidalgo, Ana Gabriela Ortega-González, Severino Rubio-Domínguez, María Cristina Rodríguez-Gutiérrez, Radamés Gaxiola-Cortés, Rodrigo Dosal-Ulloa, Laura Graciela Gochicoa-Rangel
BACKGROUND: Athletes practicing strenuous physical activities may develop exercise-induced bronchoconstriction (EIB). We aimed to determine the prevalence and features of this condition in Mexico City (altitude, 2,240 m). METHODS: In the present study, 208 high school and college athletes performed a standardized EIB test on a treadmill. RESULTS: Responses to exercise had large between-subject variability in all physiological parameters (forced expiratory volume in one second [FEV1], heart rate, blood oxygen saturation level [SpO2], blood pressure), with nearly similar proportions of subjects in whom FEV1 increased or decreased...
January 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Laura Gochicoa-Rangel, Rogelio Pérez-Padilla, Juan Carlos Vázquez-García, Mónica Silva-Cerón, Silvia Cid-Juárez, David Martínez-Briseño, Paul L Enright, Robert Jensen, Luis Torre-Bouscoulet
BACKGROUND: The 2005 American Thoracic Society/European Respiratory Society guidelines for single-breath diffusing capacity of the lung for carbon monoxide (DLCO) recommend a weekly biological control test and/or DLCO simulator to detect instrument error drift. Very little has been published regarding the results of such a quality assurance program. Our aim was to analyze the long-term stability of a portable DLCO instrument. METHODS: We used a new EasyOne Pro system and checked its accuracy using a DLCO simulator with 2 reference gases (concentration A: carbon monoxide [CO] = 0...
February 2017: Respiratory Care
Juan Carlos Vázquez-García, Rogelio Pérez-Padilla, Alejandro Casas, Patricia Schönffeldt-Guerrero, Jonatan Pereira, Claudia Vargas-Domínguez, Mónica Velázquez-Uncal, David Martínez-Briseño, Luis Torre-Bouscoulet, Laura Gochicoa-Rangel
BACKGROUND: The lung diffusion capacity (DLCO) determined by the single-breath technique greatly helps in the differential diagnosis and classification of severity of common lung diseases. However, widespread use of single-breath DLCO tests in Latin America has been limited, in part, by the lack of appropriate reference values. Our objective was to derive robust reference equations for single-breath DLCO from healthy Hispanic adults, using the most recent guidelines and taking into account altitude above sea level and hemoglobin...
September 2016: Respiratory Care
Laura Gochicoa-Rangel, Mario H Vargas, José Luis Alonso-Gómez, Luis Rodríguez-Moreno, David Martínez-Briseño, Omar Baños-Mejía, Luis Torre-Bouscoulet
Impulse oscillometry (IOS) evaluates non-effort-dependent respiratory mechanics, and thus it may be useful to evaluate patients with Duchenne muscular dystrophy (DMD). OBJECTIVES: We aimed (1) to describe the behavior of IOS parameters in patients with DMD, and compare it to those from a control group; (2) to determine whether resistances and reactances differ in relation to the severity of DMD; and (3) to compare IOS parameters with spirometry and maximal inspiratory (MIP) and expiratory (MEP) pressures...
October 2016: Pediatric Pulmonology
Laura Gochicoa-Rangel, José Rogelio Pérez-Padilla, Luis Rodríguez-Moreno, Arturo Montero-Matamoros, Nancy Ojeda-Luna, Gema Martínez-Carbajal, Roberto Hernández-Raygoza, Dolores Ruiz-Pedraza, María Rosario Fernández-Plata, Luis Torre-Bouscoulet
BACKGROUND: Altitude above sea level and body mass index are well-recognized determinants of oxygen saturation in adult populations; however, the contribution of these factors to oxygen saturation in children is less clear. OBJECTIVE: To explore the contribution of altitude above sea level and body mass index to oxygen saturation in children. METHODS: A multi-center, cross-sectional study conducted in nine cities in Mexico. Parents signed informed consent forms and completed a health status questionnaire...
November 2015: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
David Martínez-Briseño, Rosario Fernández-Plata, Laura Gochicoa-Rangel, Luis Torre-Bouscoulet, Rosalba Rojas-Martínez, Laura Mendoza-Alvarado, Cecilia García-Sancho, Rogelio Pérez-Padilla
INTRODUCTION: Our aim was to estimate the longitudinal effect of Socioeconomic status (SES) on lung function growth of Mexican children and adolescents. MATERIALS AND METHODS: A cohort of Mexican children in third grade of primary school was followed with spirometry twice a year for 6 years through secondary school. Multilevel mixed-effects lineal models were fitted for the spirometric variables of 2,641 respiratory-healthy Mexican children. Monthly family income (in 2002 U...
2015: PloS One
Laura Gochicoa-Rangel, Fermín Rojas-Cisneros, José Luis Miguel-Reyes, Selene Guerrero-Zúñiga, Uri Mora-Romero, Ana Karen Maldonado-Mortera, Luis Torre-Bouscoulet
Fraction of exhaled nitric oxide (FeNO) is a marker of eosinophilic airway inflammation. Altitude above sea level can affect measurements of this index, but there is only limited information regarding the diurnal variation (ante meridiem vs. post meridiem) and reproducibility of FeNO on consecutive days at moderate altitudes. To evaluate the diurnal variability of FeNO and assess its reproducibility over five consecutive days in healthy individuals living at 2240 m, and to compare the FeNO readings taken with two different analyzers...
August 2016: Journal of Clinical Monitoring and Computing
José Luis Miguel-Reyes, Laura Gochicoa-Rangel, Rogelio Pérez-Padilla, Luis Torre-Bouscoulet
Interstitial lung diseases are a heterogeneous group of disorders that affect, to a greater or lesser degree, the alveolus, peripheral airway, and septal interstitium. Functional assessment in patients suspected of having an interstitial lung disease has implications for diagnosis and makes it possible to objectively analyze both response to treatment and prognosis. Recently the clinical value of lung-diffusing capacity and the six-minute walking test has been confirmed, and these are now important additions to the traditional assessment of lung function that is based on spirometry...
January 2015: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Luis Torre-Bouscoulet, Mónica Velázquez-Uncal, Rogelio García-Torrentera, Laura Gochicoa-Rangel, Rosario Fernández-Plata, Paul Enright, Rogelio Pérez-Padilla
BACKGROUND: Some technologists worry that patients with very severe lung disease are unable to complete several spirometry maneuvers, which require considerable effort. METHODS: We retrospectively selected all spirometry tests with an FEV1 < 35% predicted done by adult subjects sent to our pulmonary function laboratory during a 3-y period. We determined the rates and correlates of poor quality test sessions. RESULTS: Approximately 90% of the tests done by the 558 subjects with very severe lung-function impairment (of > 30,000 subjects tested during the 3-y period) had adequate quality spirometry...
May 2015: Respiratory Care
Laura Gochicoa-Rangel, Luis Torre-Bouscoulet, David Martínez-Briseño, Luis Rodríguez-Moreno, Gabriela Cantú-González, Mario H Vargas
BACKGROUND: The impulse oscillometry system (IOS) is increasingly used to evaluate lung function, but individual results must be compared with appropriate reference values. We aimed to obtain such reference values in Mexican children and adolescents. METHODS: Healthy subjects were recruited from kindergartens and schools after their parents signed a consent letter. Respiratory system impedances (Zrs), resistances (Rrs), and reactances (Xrs) were measured at 5, 10, 15, and 20 Hz, and the resonant frequency, reactance area, and difference between Rrs5 minus Rrs20 were also calculated...
January 2015: Respiratory Care
Laura Gochicoa-Rangel, Pablo José Larios-Castañeda, José Luis Miguel-Reyes, David Martínez Briseño, Roberto Flores-Campos, Juan Arturo Sáenz-López, Luis Torre-Bouscoulet
BACKGROUND: The PIKO-6® is an electronic device that measures forced expiratory volume at seconds 1 (FEV1) and 6 (FEV6) of a forced vital capacity (FVC) maneuver. This device could aid in diagnosing obstructive respiratory diseases. OBJECTIVES: To determine the concordance of FEV1, FEV6, and the FEV1/FEV6 quotient achieved with PIKO-6® versus spirometric values from asthmatic patients, and compare results with measures from healthy children. METHODS: A cross-sectional study with asthmatic and healthy 6-to-14-year-old children, all of whom performed a forced spirometry as well as a PIKO-6® test...
December 2014: Pediatric Pulmonology
David Martínez-Briseño, Rosario Fernández-Plata, Laura Gochicoa-Rangel, Luis Torre-Bouscoulet, Rosalba Rojas-Martínez, Laura Mendoza, Cecilia García-Sancho, Rogelio Pérez-Padilla
INTRODUCTION: Our aim was to compare the longitudinal lung function growth of Mexican children and adolescents with the collated spirometric reference proposed for international use and with that of Mexican-Americans from the National Health State Examination Survey III (NHANES) III study. MATERIALS AND METHODS: A cohort of Mexican children in third year of primary school was followed with spirometry twice a year through secondary school. Multilevel mixed-effects lineal models separated by gender were fit for the spirometric variables of 2,641 respiratory-healthy Mexican children expressed as Z-scores of tested reference equations...
2013: PloS One
Laura Gochicoa-Rangel, Claudia Vargas-Domínguez, María Eugenia García-Mujica, Anaid Bautista-Bernal, Isabel Salas-Escamilla, Rogelio Pérez-Padilla, Luis Torre-Bouscoulet
INTRODUCTION: Although spirometry quality standards for children were proposed by American Thoracic Society/European Respiratory Society (ATS/ERS) in 2007, there is limited information on the percentage of children that fulfill these criteria during routine clinical testing, especially among 5-to-8-year-olds. AIMS OF THE STUDY: to report the percentage of children that met the current 2007 ATS/ERS quality criteria; explore factors potentially associated with poor quality spirometry; and ascertain the repeatability of forced expiratory volume at 0...
December 2013: Pediatric Pulmonology
Fortino Solórzano Santos, Laura G Gochicoa Rangel, Gerardo Palacios Saucedo, Guillermo Vázquez Rosales, María Guadalupe Miranda Novales
BACKGROUND: Adverse effects associated with highly active antiretroviral therapy (HAART), particularly protease inhibitors (PIs), have been identified in adult and pediatric patients. In this study, we monitored, for cholesterol and triglyceride levels, a cohort of HIV-1-infected children receiving a HAART regimen. METHODS: HIV-infected patients <17 years old belonging to a cohort that has been followed since 1997 were enrolled in the study. Patients were receiving either a three- or four-drug antiretroviral regimen that included two nucleoside reverse transcriptase inhibitors (lamivudine and zidovudine) combined with one or two PIs (ritonavir and/or saquinavir)...
January 2006: Archives of Medical Research
Jorge L Ramírez-Figueroa, Laura G Gochicoa-Rangel, David H Ramírez-San Juan, Mario H Vargas
Rigid bronchoscopy is the preferred method for removal of foreign bodies lodged in the airways, but some studies found that flexible bronchoscopy can also achieve a high success rate. The aim of the present work was to report our experience in using flexible bronchoscopy for foreign body retrieval in infants and children. Reports of all bronchoscopies performed from 1994-2003 at a tertiary-level pediatric hospital in Mexico City were reviewed. Those with a final diagnosis of foreign body aspiration were analyzed...
November 2005: Pediatric Pulmonology
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