Kensaku Fukunaga, Hitomi Imachi, Seisuke Sato, Toshihiro Kobayashi, Yuki Yoshioka, Takanobu Saheki, Natsuki Ban, Kurumi Urushihara, Jingya Lyu, Tao Dong, Ryou Ishikawa, Kyuichi Kadota, Reiji Haba, Naoko Inoshita, Koji Murao
It is quite rare that Cushing's disease shows acromegaly, and no pharmacotherapy has yet been discussed. A 21-year-old woman was diagnosed with Cushing's disease and underwent trans-sphenoidal surgery. Five years later, she was diagnosed with recurrent Cushing's disease and biochemical acromegaly because of elevated levels of serum growth hormone (GH), plasma insulin-like growth factor-1, plasma adrenocorticotropic hormone (ACTH), and the 24-h urinary excretion of free cortisol. After treatment initiation with pasireotide-long-acting release (LAR), both the ACTH and GH declined...
November 9, 2020: Internal Medicine