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https://www.readbyqxmd.com/read/29041034/inhaled-versus-systemic-corticosteroids-for-preventing-bronchopulmonary-dysplasia-in-ventilated-very-low-birth-weight-preterm-neonates
#1
REVIEW
Sachin S Shah, Arne Ohlsson, Henry L Halliday, Vibhuti S Shah
BACKGROUND: Bronchopulmonary dysplasia (BPD) remains an important cause of mortality and morbidity in preterm infants and inflammation plays a significant role in its pathogenesis. The use of inhaled corticosteroids may modulate the inflammatory process without concomitant high systemic steroid concentrations and less risk of adverse effects. This is an update of a review published in 2012 (Shah 2012). We recently updated the related review on "Inhaled versus systemic corticosteroids for treating bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates"...
October 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29040820/systematic-review-of-the-effect-of-enteral-feeding-on-gut-microbiota-in-preterm-infants
#2
Wanli Xu, Michelle Judge, Kendra Maas, Naveed Hussain, Jacqueline M McGrath, Wendy A Henderson, Xiaomei Cong
OBJECTIVE: To examine the effect of feeding type on microbial patterns among preterm infants and to identify feeding factors that promote the colonization of beneficial bacteria. DATA SOURCES: PubMed, Cochrane Database of Systematic Reviews, Scopus, and the Cummulative Index of Nursing and Allied Health Literature were thoroughly searched for articles published between January 2000 and January 2017, using the keywords gut microbiome, gut microbiota, enteral microbiome, enteral microbiota, premature infant, preterm infant, extremely low birth weight infant, ELBW infant, very low birth weight infant, feeding, breast milk, breastfeeding, formula, prebiotic, probiotic, and long chain polyunsaturated fatty acid...
October 14, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/29036471/immunization-completion-in-infants-born-at-low-birth-weight
#3
Matt Nestander, Jay Dintaman, Apryl Susi, Gregory Gorman, Elizabeth Hisle-Gorman
Background: Low birth weight (LBW) has been associated with underimmunization. We sought to understand the effect of LBW on immunization completion after controlling for previously hypothesized mediators, including prematurity, neonatal illness, well-child care, non-well-child visits, and provider consistency. Methods: We formed a retrospective cohort of infants born between 2008 and 2011 with ≥2 years of military healthcare follow-up. International Classification of Diseases, Ninth Revision codes were used to identify LBW, preterm birth, neonatal illnesses, well-child visits, non-well-child visits, provider consistency, and parental rank in the inpatient and outpatient records...
September 23, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29035425/inhaled-versus-systemic-corticosteroids-for-the-treatment-of-bronchopulmonary-dysplasia-in-ventilated-very-low-birth-weight-preterm-infants
#4
REVIEW
Sachin S Shah, Arne Ohlsson, Henry L Halliday, Vibhuti S Shah
BACKGROUND: This is an update of a review published in 2012. A related review "Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates" has been updated as well. Bronchopulmonary dysplasia (BPD) is a serious and common problem among very low birth weight infants, despite the use of antenatal steroids and postnatal surfactant therapy to decrease the incidence and severity of respiratory distress syndrome. Due to their anti-inflammatory properties, corticosteroids have been widely used to treat or prevent BPD...
October 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29031388/postnatal-rbc-arachidonic-and-docosahexaenoic-acids-deficiencies-are-associated-with-higher-risk-of-neonatal-morbidities-and-mortality-in-preterm-infants
#5
S Fares, M M Sethom, M B Hammami, M Cheour, M Feki, S Hadj-Taieb, S Kacem
Arachidonic (AA) and docosahexaenoic (DHA) acids are essential for the health and development of the neonate. Red blood cell (RBC) fatty acids were analyzed in 583 very low birth weight (VLBW) infants and 274 term infants using capillary gas chromatography. VLBW infants exhibited significantly lower RBC AA (13.0 ± 0.89 vs. 13.5 ± 0.98) and DHA (3.77 ± 0.60 vs. 3.80 ± 0.62), but higher n6:n3 ratio (3.97 ± 0.46 vs. 3.63 ± 0.37) than term infants. In VLBW infants, DHA was lower in those born with small for gestational age (3...
November 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/29030727/-parenteral-nutrition-in-premature-babies-with-a-birth-weight-1500g-a%C3%A2-systematic-single-center-analysis-and-comparison-with-current-guidelines
#6
Melanie Sirch, Martin Poryo, Mona Butte, Ulrike Lindner, Ludwig Gortner, Michael Zemlin, Holger Nunold, Sascha Meyer
BACKGROUND: Parenteral and enteral nutrition are essential for both growth and development of preterm infants. Based on the results of many studies, the rate of nutritional growth and the amount of substrate delivered parenterally are under debate. OBJECTIVE: The main aim of this study was to assess parenteral nutrition in very and extremely immature preterm infants, i.e. very low birth weight (VLBW, birth weight <1500g) and extremely low birth weight (ELBW, birth weight <1000g) neonates, and to compare the amount of parenterally delivered substrate in our neonatal intensive care unit (NICU) to current German guidelines...
October 13, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29024833/health-of-vlbw-infants-in-germany-at-five-years-of-age-what-do-parents-describe
#7
Juliane Spiegler, Guido Stichtenoth, Inke R König, Egbert Herting, Wolfgang Göpel
BACKGROUND: There are only few data on medical problems and utilization of health services of former very low birth weight (VLBW) children at preschool age. STUDY DESIGN: At five years of age parents of a cohort of VLBW children (N=862) received questionnaires, a medical interview and examination. The results were compared to the KIGGS cohort (Deutscher-Kinder-und Jugendgesundheitssurvey, N=777). RESULTS: Parents of the VLBW and KIGGS cohort reported a very good or good health in 95% in their children...
October 9, 2017: Early Human Development
https://www.readbyqxmd.com/read/29022536/short-term-outcomes-of-inborn-v-outborn-very-low-birth-weight-neonates-1-500-g-in-the-neonatal-nursery-at-groote-schuur-hospital-cape-town-south-africa
#8
L Gibbs, L Tooke, M C Harrison
BACKGROUND: The Groote Schuur Hospital (GSH) neonatal nursery provides level 3 care for the Metro West Health District in the Western Cape Province of South Africa. Worldwide, very-low-birth-weight (VLBW) neonates delivered in level 3 neonatal units have better outcomes than those transported from other facilities. OBJECTIVES: To identify the characteristics and outcomes of VLBW neonates at GSH, with emphasis on differences between inborns and outborns. METHODS: This was a retrospective cohort study...
September 22, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29019472/microbiological-monitoring-of-continuous-positive-airway-pressure-and-resuscitation-equipment-in-very-low-birth-weight-infants
#9
Torben Christian Winking, Jörg Wüllenweber, Frank Kipp, Esther Rieger-Fackeldey
BackgroundTo investigate the colonization of respiratory equipment and the rate of respiratory infections of very-low birth weight (VLBW) infants.MethodsThe prospective study includes 26 VLBW infants on continuous airway pressure (CPAP) from September until December 2012. Swabs from respiratory equipment and colonization/infections were evaluated.ResultsA total of 603 swabs was cultured with 298 isolates; 59% of cultures from CPAP equipment (n=337; 95% confidence interval (CI; 54;64)) and 19% from ambu bags (n=51; 95% CI (14;24)) were positive...
October 11, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28991764/hypoglycaemia-in-the-newborn
#10
Orhideja Stomnaroska, Elizabeta Petkovska, Sanja Ivanovska, Snezana Jancevska, Dragan Danilovski
AIM: Severe neonatal hypoglycaemia (HG) leads to neurologic damage, mental retardation, epilepsy, impaired cardiac performance and muscle weakness. The aim was to assess the frequency and severity of HG in a population of newborns. PATIENTS AND METHODS: We investigated 739 patients with neonatal hypoglycaemia (HG) (M:F=370:369) born at the University Clinic for Gynaecology and Obstetritics in Skopje in the period 2014-2016 and treated at the neonatal intensive care unit (NICU)...
September 1, 2017: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/28989948/morbidity-in-%C3%A2-1500-gram-births-in-spain-1993-2011-study-of-a-sample-of-1200-cases
#11
Concepción Gómez Esteban, Juan J Sánchez Carrión, Fernando J García Selgas, José M Segovia Guisado
Background and Objective. Preterm birth has a major impact on growth, and very preterm birth is associated with disabilities in numerous developmental domains. This article describes and quantifies morbidities in a sample of 1200 ≤1500-g births in Spain between 1993 and 2011 based on parent information, and it highlights several variables that influence these morbidities. Methods. Multiple method surveys using computer-assisted telephones interviewing and computer-assisted web interviewing methods. Sample design was intentional...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28977653/to-compare-the-efficacy-of-heated-humidified-high-flow-nasal-cannula-and-continuous-positive-airway-pressure-in-post-extubation-period-in-vlbw-infants
#12
Bhawan Deep Garg, Naveen Bajaj, Deepak Sharma
Objective: The objective of this study was to compare efficacy of continuous positive airway pressure (CPAP) and heated humidified high-flow nasal cannula (HHHFNC) as noninvasive respiratory support in post-extubation period in very low birth weight (VLBW) infants. Method: This retrospective study enrolled 136 neonates, ≤32 weeks gestation and ≤1500 grams birth weight, requiring noninvasive respiratory support during post-extubation period. Results: There was no significant difference in post-extubation failure in HHHFNC group when compared with CPAP group ( p  > 0...
August 8, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28977291/the-nutritional-status-of-hospitalized-children-and-adolescents-a-comparison-between-two-nutritional-assessment-tools-with-anthropometric-parameters
#13
Thaynara Cristina de Oliveira, Izabela Zibetti de Albuquerque, Maria Luiza Ferreira Stringhini, Andrea Sugai Mortoza, Bruna Alves de Morais
OBJECTIVE: Verify the association between anthropometric indicators and the Subjective Global Assessment of Nutritional Status (SGA) and the Screening of Risk for Nutritional Status and Growth (STRONGkids) scales. METHODS: A cross-sectional study with patients from 0 to 18 years admitted in the Hospital das Clínicas, Goiânia (GO), between August and November 2015. Children and adolescents admitted in up to 48 hours were included. Patients who required specific instruments for assessing their nutritional status and those hospitalized in Intensive Care were excluded...
July 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/28969888/regional-variation-in-neonatal-intensive-care-admissions-and-the-relationship-to-bed-supply
#14
Wade N Harrison, Jared R Wasserman, David C Goodman
OBJECTIVE: To characterize geographic variation in neonatal intensive care unit (NICU) admission rates across the entire birth cohort and evaluate the relationship between regional bed supply and NICU admission rates. STUDY DESIGN: This was a population-based, cross-sectional study. 2013 US birth certificate and 2012 American Hospital Association data were used to assign newborns and NICU beds to neonatal intensive care regions. Descriptive statistics of admission rates were calculated across neonatal intensive care regions...
September 29, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28969546/igf-1-as-a-drug-for-preterm-infants-a-step-wise-clinical-development
#15
Ann Hellstrom, David Ley, Boubou Hallberg, Chatarina Lofqvist, Ingrid Hansen-Pupp, Luca A Ramenghi, Jan Borg, Lois E H Smith, Anna-Lena Hard
BACKGROUND: Insulin-like growth factor 1 (IGF-1) is a mitogenic hormone involved in many processes such as growth, metabolism, angiogenesis and differentiation. After very preterm birth, energy demands increase while maternal supplies of nutrients and other factors are lost and the infant may become dependent on parenteral nutrition for weeks. Low postnatal IGF-1 concentrations in preterm infants are associated with poor weight gain, retinopathy of prematurity (ROP) and other morbidities...
October 2, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28968426/neuroimaging-of-decoding-and-language-comprehension-in-young-very-low-birth-weight-vlbw-adolescents-indications-for-compensatory-mechanisms
#16
Helene van Ettinger-Veenstra, Carin Widén, Maria Engström, Thomas Karlsson, Ingemar Leijon, Nina Nelson
In preterm children with very low birth weight (VLBW ≤ 1500 g), reading problems are often observed. Reading comprehension is dependent on word decoding and language comprehension. We investigated neural activation-within brain regions important for reading-related to components of reading comprehension in young VLBW adolescents in direct comparison to normal birth weight (NBW) term-born peers, with the use of functional magnetic resonance imaging (fMRI). We hypothesized that the decoding mechanisms will be affected by VLBW, and expect to see increased neural activity for VLBW which may be modulated by task performance and cognitive ability...
2017: PloS One
https://www.readbyqxmd.com/read/28965850/trends-in-birth-weight-specific-and-adjusted-infant-mortality-rates-in-taiwan-between-2004-and-2011
#17
Fu-Wen Liang, Hung-Chieh Chou, Shu-Ti Chiou, Li-Hua Chen, Mei-Hwan Wu, Hung-Chi Lue, Tung-Liang Chiang, Tsung-Hsueh Lu
BACKGROUND: A yearly increase in the proportion of very low birth weight (VLBW) live births has resulted in the slowdown of decreasing trends in crude infant mortality rates (IMRs). In this study, we examined the trends in birth weight-specific as well as birth weight-adjusted IMRs in Taiwan. METHODS: We linked three nationwide datasets, namely the National Birth Reporting Database, National Birth Certification Registry, and National Death Certification Registry databases, to calculate the IMRs according to the birth weight category...
September 4, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28964428/surgical-interventions-in-infants-born-preterm-with-congenital-heart-defects-an-analysis-of-the-kids-inpatient-database
#18
Jagdish Desai, Sanjeev Aggarwal, Steven Lipshultz, Prashant Agarwal, Paulos Yigazu, Riddhiben Patel, Samantha Seals, Girija Natarajan
OBJECTIVE: To evaluate short-term outcomes in infants born preterm with congenital heart defects (CHDs) and the factors associated with surgery, survival, and length of hospitalization in this population. STUDY DESIGN: We analyzed data from infants born preterm (gestational age <37 weeks) enrolled in the multicenter Kids' Inpatient Database of the Healthcare Cost and Utilization Project who were admitted to the hospital within 30 days after birth. Infants with atrial septal defects were excluded...
September 27, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28960518/high-sensitivity-c-reactive-protein-concentration-in-young-adults-in-the-helsinki-study-of-very-low-birth-weight-adults
#19
Kai Yin Ho, Rie Goto, Pieta Näsänen-Gilmore, Sture Andersson, Johan G Eriksson, Eero Kajantie, Petteri Hovi
Low birth weight and chronic low-grade inflammation have been significantly associated with an increased risk of cardiovascular disease (CVD) (1,2). C-reactive protein (CRP) is a highly sensitive biomarker that is used to detect the inflammation associated with predictive factors related to CVD, such as atherogenesis or atherosclerosis (3). Adults born preterm at a very low birth weight (VLBW) of less than 1,500g represent the low end of the low birth weight spectrum and have increased levels of CVD risk factors (4)...
September 28, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28957424/nutrition-after-preterm-birth-and-adult-neurocognitive-outcomes
#20
Sara Sammallahti, Eero Kajantie, Hanna-Maria Matinolli, Riikka Pyhälä, Jari Lahti, Kati Heinonen, Marius Lahti, Anu-Katriina Pesonen, Johan G Eriksson, Petteri Hovi, Anna-Liisa Järvenpää, Sture Andersson, Katri Raikkonen
BACKGROUND: Preterm birth (<37 gestational weeks) poses a risk of poorer neurocognitive functioning. Faster growth after preterm birth predicts better cognitive abilities and can be promoted through adequate nutrition, but it remains unknown whether variations in nutrient intakes translate into long-term benefits for neurodevelopment. METHODS: In 86 participants of the Helsinki Study of Very Low Birth Weight Adults (birthweight <1500g), we examined if higher intakes of energy, macronutrients, and human milk during the first nine weeks after preterm birth predict performance in tests of cognitive ability at 25...
2017: PloS One
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