keyword
MENU ▼
Read by QxMD icon Read
search

Extreme prematurity

keyword
https://www.readbyqxmd.com/read/29333826/vitamin-d-deficiency-in-pediatric-clinical-practice
#1
Gustavo Cediel, Johanna Pacheco-Acosta, Carlos CastiUo-Durdn
INTRODUCTION: Vitamin D research suggests it has a role in disorders other than bone metabolism. OBJECTIVE: To update the information on vitamin D deficiency (VDD) in pediatric clinical disorders. METHODS: Search in virtual libraries, giving priority to clinical and longitudinal studies and meta-analyses on VDD in the pediatric age group published in the past 20 years. The terms "vitamin D deficiency", "children and adolescents" (both in Spanish and English) were used as search descriptors...
February 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29320482/severe-retinopathy-of-prematurity-is-associated-with-reduced-cerebellar-and-brainstem-volumes-at-term-and-neurodevelopmental-deficits-at-two-years
#2
Femke J Drost, Kristin Keunen, Pim Moeskops, Nathalie H P Claessens, Femke van Kalken, Ivana Išgum, Elsbeth S M Voskuil-Kerkhof, Floris Groenendaal, Linda S de Vries, Manon J N L Benders, Jacqueline U M Termote
OBJECTIVE: To evaluate the association between severe retinopathy of prematurity (ROP), measures of brain morphology at term equivalent age (TEA) and neurodevelopmental outcome. PATIENTS AND METHODS: 18 infants with severe ROP (median gestational age (GA) 25.3 (range 24.6-25.9 weeks) were included in this retrospective case-control study. Each infant was matched to two extremely preterm control infants (n=36) by GA, birth weight, sex and brain injury. T2-weighted images were obtained on a 3T MRI at TEA...
January 10, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29316378/longitudinal-assessment-of-lung-function-in-extremely-prematurely-born-children
#3
Jessica Lo, Sanja Zivanovic, Alan Lunt, Mireia Alcazar-Paris, Gwendolyn Andradi, Mark Thomas, Neil Marlow, Sandy Calvert, Janet Peacock, Anne Greenough
OBJECTIVES: To assess longitudinally small airway function in children born extremely prematurely and whether there was a correlation between airway function in infancy and at 11-14 years. WORKING HYPOTHESES: There would be tracking of airways obstruction and small airway function would deteriorate during childhood in those born extremely prematurely. STUDY DESIGN: A longitudinal study. PATIENT-SUBJECT SELECTION: Thirty-five children with a mean gestational age of 26 weeks had lung function assessed at 1 year corrected and 11-14 years of age...
January 9, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29313560/surgical-closure-of-patent-ductus-arteriosus-in-extremely-low-birth-weight-infants-less-than-750-grams
#4
Tomasz Stankowski, Sleiman Sebastian Aboulhassan, Dirk Fritzsche, Marcin Misterski, Jakub Marczak, Anna Szymańska, Lukasz Szarpak, Cyprian Augustyn, Romuald Cichoń, Bartłomiej Perek
BACKGROUND: Patent ductus arteriosus (PDA) occurs more frequently in premature infants. Depending on the degree of prematurity, these children often have other serious comorbidities that could significantly impact on surgical outcome. AIM: This study aimed to evaluate clinical results of the surgical ligation of PDA in extremely low body weight preterm infants with birth weight below 750 grams and to identify risk factors of mortality. METHODS: A total of 31 preterm infants with birth weight below 750 grams and significant PDA were operated between 2006 and 2016 through posterolateral thoracotomy (n=16) or with the use of video-assisted thoracoscopic (VATS) method (n = 15)...
January 9, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29309831/mutant-cartilage-oligomeric-matrix-cartilage-comp-compromises-bone-integrity-joint-function-and-the-balance-between-adipogenesis-and-osteogenesis
#5
Francoise Coustry, Karen L Posey, Tristan Maerz, Kevin Baker, Annie M Abraham, Catherine G Ambrose, Sabah Nobakhti, Sandra J Shefelbine, Xiaohong Bi, Michael Newton, Karissa Gawronski, Lindsay Remer, Alka C Veerisetty, Mohammad G Hossain, Frankie Chiu, Jacqueline T Hecht
Mutations in COMP (cartilage oligomeric matrix protein) cause severe long bone shortening in mice and humans. Previously, we showed that massive accumulation of misfolded COMP in the ER of growth plate chondrocytes in our MT-COMP mouse model of pseudoachondroplasia (PSACH) causes premature chondrocyte death and loss of linear growth. Premature chondrocyte death results from activation of oxidative stress and inflammation through the CHOP-ER pathway and is reduced by removing CHOP or by anti-inflammatory or antioxidant therapies...
January 5, 2018: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/29306492/outcomes-of-surgical-ligation-after-unsuccessful-pharmacotherapy-for-patent-ductus-arteriosus-in-neonates-born-extremely-preterm
#6
Dany E Weisz, Lucia Mirea, Maura H F Resende, Linh Ly, Paige T Church, Edmond Kelly, S Joseph Kim, Amish Jain, Patrick J McNamara, Prakesh S Shah
A retrospective cohort study of neonates born extremely preterm with persistent patent ductus arteriosus after unsuccessful pharmacologic closure compared outcomes between 166 surgically ligated and 142 nonligated neonates. After adjustment for confounders, ligation was not associated with the composite outcome of death or neurodevelopmental impairment, neurodevelopmental impairment alone, chronic lung disease, or retinopathy of prematurity among survivors.
January 3, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29300196/mesenteric-oxygenation-changes-associated-with-necrotizing-enterocolitis-and-pneumoperitoneum-after-multiple-blood-transfusions-a-case-report
#7
Terri Marin, James E Moore
BACKGROUND: The multifactorial pathology and broad clinical presentation of necrotizing enterocolitis (NEC) development in premature infants make prediction of disease onset extremely challenging. Over the past decade, packed red blood cell (PRBC) transfusions have been temporally linked to the development of NEC in severely anemic preterm infants, although this issue is highly controversial. PURPOSE: In this case study, we describe events of an extremely low birth-weight infant who developed NEC complicated by pneumoperitoneum after receiving multiple PRBC transfusions...
January 3, 2018: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/29299961/erythromelalgia
#8
Peter Franz Klein-Weigel, Theresa Sophie Volz, Jutta Gisela Richter
Erythromelalgia is a rare syndrome characterized by the intermittent or, less commonly, by the permanent occurrence of extremely painful hyperperfused skin areas mainly located in the distal extremities. Primary erythromelalgia is nowadays considered to be a genetically determined neuropathic disorder affecting SCN9A, SCN10A, and SCN11A coding for NaV1.7, NaV1.8, and NaV1.9 neuronal sodium channels. Secondary forms might be associated with myeloproliferative disorders, connective tissue disease, cancer, infections, and poisoning...
January 4, 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29298985/selenium-implications-for-outcomes-in-extremely-preterm-infants
#9
REVIEW
Rachael Tindell, Trent Tipple
Extremely preterm infants are at high risk for morbidities including bronchopulmonary dysplasia, intraventricular hemorrhage, and retinopathy of prematurity likely related to their exposure to reactive oxygen and nitrogen species early in life. Selenium is a trace mineral contributes to the proper function of multiple systems including immunity, redox regulation, and inflammation via the "selenoenzymes" glutathione peroxidase, thioredoxin reductase, and selenoprotein P. Given that selenium accretion via the placenta occurs primarily during the third trimester, preterm neonates are born selenium deficient...
January 3, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29298856/persistent-pulmonary-hypertension-of-the-newborn-in-extremely-preterm-infants-a-japanese-cohort-study
#10
Hidehiko Nakanishi, Hideyo Suenaga, Atsushi Uchiyama, Satoshi Kusuda
OBJECTIVE: To investigate the characteristics of persistent pulmonary hypertension of the newborn (PPHN) in extremely preterm infants and its impact on neurodevelopmental outcomes at 3 years of age. DESIGN: A retrospective multicentre cohort study. SETTINGS: 202 tertiary perinatal centres registered in the Neonatal Research Network of Japan (NRNJ). PATIENTS: Infants born at <28 weeks of gestational age (GA), between 2003 and 2012, were extracted from tertiary perinatal centres participating in NRNJ...
January 3, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29290747/acetaminophen-for-patent-ductus-arteriosus-in-extremely-low-birth-weight-neonates
#11
Caitlyn M Luecke, Caren J Liviskie, Brandy N Zeller, Zachary A Vesoulis, Christopher McPherson
OBJECTIVE: Although non-steroidal anti-inflammatory drugs (NSAIDs) are the current standard therapy for the treatment of patent ductus arteriosus (PDA), many neonates have contraindications to receiving or may fail NSAID therapy. To avoid surgical ligation, these patients may benefit from an alternative therapy. The objective of this research is to report the efficacy and safety of acetaminophen for the treatment of PDA in a cohort of premature neonates. METHODS: Demographics and clinical course were retrospectively evaluated for all neonates admitted during the study period who received acetaminophen for the treatment of PDA...
November 2017: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/29285339/medium-chain-acyl-coa-dehydrogenase-deficiency-in-a-premature-infant
#12
Steven F Dobrowolski, Lina Ghaloul-Gonzalez, Jerry Vockley
Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is identified by newborn screening (NBS). The natural history of MCADD includes metabolic decompensation with hypoglycemia, hyperammonemia, seizures, coma, and death. NBS enables expectant management thus severe symptoms are rare in managed patients. We report premature birth of an MCADD affected infant and resultant management challenges. Nutritional support advanced from parenteral nutrition at 24 hours to enteral feeds. A NBS sample was collected day 2, positive results for MCADD was reported day six, and diagnostic tests were performed day seven...
November 21, 2017: Pediatric Reports
https://www.readbyqxmd.com/read/29281936/a-comparative-study-of-hhhfnc-and-ncpap-in-preventing-reintubation-in-extreme-preterm-infants-born-at-less-than-30-week-gestation
#13
W Muhsen, R Roy
INTRODUCTION: Despite recent advances in respiratory support, the wide use of antenatal steroids and surfactant replacement therapy, respiratory problems continue to represent the leading cause of mortality in premature infants during the neonatal period. In the last few years, HHHFNC has been widely adopted as a mode of noninvasive respiratory support for infants with respiratory difficulties. However, data of the safety and efficacy of HHHFNC use in extremely premature infants are scarce...
December 27, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29281748/extreme-prematurity-treated-retinopathy-bronchopulmonary-dysplasia-and-cerebral-palsy-are-significant-risk-factors-for-ophthalmological-abnormalities-at-6-5-years-of-age
#14
Ann Hellström, Karin Källén, Birgitta Carlsson, Gerd Holmström, Peter Jakobsson, Pia Lundgren, Fredrik Serenius, Karin Stjernqvist, Kristina Tornqvist, Kerstin Hellgren
AIM: This study evaluated the contributions of various prenatal and postnatal predictive factors to a documented high prevalence of ophthalmological abnormalities in children aged 6.5 years who were born extremely preterm. METHODS: We carried out a prospective population-based study of all children born in Sweden at a gestational age of 22+0 to 26+6 weeks based on the Extremely Preterm Infants in Sweden Study. The main outcome measures were a combined score of visual impairment, refractive errors and strabismus at 6...
December 27, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29278644/endothelial-cells-of-extremely-premature-infants-display-impaired-immune-response-after-proinflammatory-stimulation
#15
Lukas Wisgrill, Martina Muck, Isabelle Wessely, Angelika Berger, Andreas Spittler, Elisabeth Förster-Waldl, Kambis Sadeghi
BACKGROUND: Endothelial cells (ECs) exert immunological functions such as production of proinflammatory cytokines/chemokines as well as facilitation of extravasation of immune cells into infected tissue. Limited data are available on the functionality of ECs from extremely preterm neonates during infection. Accordingly, the aim of our study was to investigate the immune response of premature ECs after proinflammatory stimulation. METHODS: Cell adhesion receptors expression and function, NFkB-signaling and chemokine production were analyzed in umbilical cord ECs from extremely preterm and term neonates after proinflammatory stimulation...
August 21, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29275242/maternal-cumulative-exposure-to-extremely-low-frequency-electromagnetic-fields-and-pregnancy-outcomes-in-the-elfe-cohort
#16
L Migault, C Piel, C Carles, F Delva, A Lacourt, E Cardis, C Zaros, R de Seze, I Baldi, G Bouvier
OBJECTIVES: To study the relations between maternal cumulative exposure to extremely low frequency electromagnetic fields (ELF EMF) and the risk of moderate prematurity and small for gestational age within the Elfe cohort. METHODS: The Elfe study included 18,329 infants born at 33weeks of gestation or more in France in 2011 and was designed to follow the children until 20years of age. Gestational age and anthropometric data at birth were collected in medical records and small for gestational age was defined according to a French customized growth standard...
December 20, 2017: Environment International
https://www.readbyqxmd.com/read/29260199/systemic-inflammation-associated-proteins-and-retinopathy-of-prematurity-in-infants-born-before-the-28th-week-of-gestation
#17
Mari Holm, Tora S Morken, Raina N Fichorova, Deborah K VanderVeen, Elizabeth N Allred, Olaf Dammann, Alan Leviton
Purpose: To assess the association between systemic levels of inflammation-associated proteins and severe retinopathy of prematurity (ROP) in extremely preterm infants. Methods: We collected whole blood on filter paper on postnatal days 1, 7, 14, 21, and 28 from 1205 infants born before the 28th week of gestation, and measured the concentrations of 27 inflammation-associated, angiogenic, and neurotrophic proteins. We calculated odds ratios with 95% confidence intervals for the association between top quartile concentrations of each protein and prethreshold ROP...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29260194/corneal-aberrations-in-former-preterm-infants-results-from-the-wiesbaden-prematurity-study
#18
Achim Fieß, Alexander K Schuster, Ruth Kölb-Keerl, Markus Knuf, Bernd Kirchhof, Philipp S Muether, Jacqueline Bauer
Purpose: To compare corneal aberrations in former preterm infants to that of full-term infants. Methods: A prospective cross-sectional study was carried out measuring the corneal shape with Scheimpflug imaging in former preterm infants of gestational age (GA) ≤32 weeks and full-term infants with GA ≥37 weeks now being aged between 4 to 10 years. The main outcome measures were corneal aberrations including astigmatism (Zernike: Z2-2; Z22), coma (Z3-1; Z31), trefoil (Z3-3; Z33), spherical aberration (Z40) and root-mean square of higher-order aberrations (RMS HOA)...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29246927/disruption-of-interneuron-neurogenesis-in-premature-newborns-and-reversal-with-estrogen-treatment
#19
Mahima Tibrewal, Bokun Cheng, Preeti Dohare, Furong Hu, Rana Mehdizadeh, Ping Wang, Deyou Zheng, Zoltan Ungvari, Praveen Ballabh
Preterm-born children suffer from neurobehavioral disorders. Premature birth terminates the hypoxic in utero environment and supply of maternal hormones. As the production of interneurons continues until the end of pregnancy, we hypothesized that premature birth would disrupt interneuron production and restoration of the hypoxic milieu or estrogen treatment might reverse interneuron generation. To test these hypotheses, we quantified interneuronal progenitors in the medial, lateral, and caudal ganglionic eminences (MGE, LGE, and CGE) of preterm- (E29 at D3 and D7) vs...
December 15, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29244802/elevations-of-inflammatory-proteins-in-neonatal-blood-are-associated-with-obesity-and-overweight-among-2-year-old-children-born-extremely-premature
#20
Eliana M Perrin, T Michael O'Shea, Asheley Cockrell Skinner, Carl Bose, Elizabeth N Allred, Raina N Fichorova, Jelske W van der Burg, Alan Leviton
BACKGROUND: Childhood obesity is associated with elevated blood concentrations of inflammation markers. It is not known to what extent inflammation precedes the development of obesity. METHODS: In a cohort of 882 infants born before 28 weeks of gestation, we examined relationships between concentrations of 25 inflammation-related proteins in blood obtained during the first two postnatal weeks and body mass index at 2 years of age. RESULTS: Among children delivered for spontaneous indications (n=734), obesity was associated with elevated concentrations of four proteins (IL-1β, IL-6, TNF-R1, and MCP-1) on the first postnatal day; one protein (IL-6) on postnatal day 7; and two proteins (ICAM-3 and VEGF-R1) on postnatal day 14...
December 15, 2017: Pediatric Research
keyword
keyword
25301
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"