keyword
MENU ▼
Read by QxMD icon Read
search

Extreme prematurity

keyword
https://www.readbyqxmd.com/read/28937410/cerebral-oxygenation-of-premature-lambs-supported-by-an-artificial-placenta
#1
Ahmed M El-Sabbagh, Brian W Gray, Andrew W Shaffer, Benjamin S Bryner, Joseph T Church, Jennifer S McLeod, Sara Zakem, Elena M Perkins, Renée A Shellhaas, John D E Barks, Alvaro Rojas-Peña, Robert H Bartlett, George B Mychaliska
An artificial placenta (AP) using venovenous extracorporeal life support (VV-ECLS) could represent a paradigm shift in the treatment of extremely premature infants. However, AP support could potentially alter cerebral oxygen delivery. We assessed cerebral perfusion in fetal lambs on AP support using near-infrared spectroscopy (NIRS) and carotid arterial flow (CAF). Fourteen premature lambs at EGA 130 days (term = 145) underwent cannulation of the right jugular vein and umbilical vein with initiation of VV-ECLS...
September 20, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28937079/neonatal-bartter-syndrome-in-an-extremely-low-birth-weight-baby
#2
Deeparaj Hegde, Jayashree Mondkar, Nitinkumar Abdagire
Early diagnosis of Bartter syndrome (BS) in the neonatal period is a clinical challenge, more so in an extremely low birth weight (ELBW) baby because of the inherent renal immaturity and the associated difficulty in fluid management. However, once a diagnosis is made, the disorder is known to respond well to fluid and electrolyte management, prostaglandin inhibitors, and potassium-sparing diuretics. Herein, we report a case of neonatal BS in a very premature ELBW infant.
September 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28934640/continuous-longitudinal-infusion-of-rhigf-1-rhigfbp-3-in-extremely-preterm-infants-evaluation-of-feasibility-in-a-phase-ii-study
#3
Ingrid Hansen-Pupp, Ann Hellström, Mohamed Hamdani, Adina Tocoian, Nerissa C Kreher, David Ley, Boubou Hallberg
OBJECTIVE: To evaluate the feasibility of continuous longitudinal intravenous infusion of recombinant human insulin-like growth factor-1/recombinant human insulin-like growth factor binding protein-3 (rhIGF-1/rhIGFBP-3) for prevention of retinopathy of prematurity and other complications in extremely preterm infants (<28weeks' gestational age), based on initial sections of a phase II randomized controlled trial. DESIGN: The phase II trial was designed in four sections (A-D); we report pharmacokinetic and adverse events (AEs) data pooled for Sections B and C...
August 31, 2017: Growth Hormone & IGF Research
https://www.readbyqxmd.com/read/28931575/case-report-of-clitoral-hypertrophy-in-2-extremely-premature-girls-with-an-ovarian-cyst
#4
Anne-Laure Nerré, Pierre Bétrémieux, Sylvie Nivot-Adamiak
Neonatal clitoromegaly is mainly attributed to in utero androgen exposure secondary to congenital adrenal hyperplasia. We report on 2 extremely premature girls with clitoromegaly, increased androgen levels, no salt wasting syndrome, and ovarian cyst. In case 1, the cyst liquid was aspired during ovarian hernia surgery and revealed high androgen levels. After aspiration, serum androgen levels decreased, as did clitoral size. In case 2, an ovarian cyst was seen on pelvic ultrasound. Aspiration was not indicated...
September 20, 2017: Pediatrics
https://www.readbyqxmd.com/read/28921657/reporting-anxiety-symptoms-in-extremely-preterm-born-adolescents-and-by-their-mothers
#5
M J Sømhovd, B H Esbjørn, B M Hansen, G Greisen
AIM: To compare anxiety symptoms in adolescents born extremely prematurely to term-born controls. METHODS: We had 96 preterm-born adolescents and 40 term-born controls from Denmark and their mothers score the adolescents on the Revised Children Anxiety and Depression scale. We analysed group differences, cross-informant correlations, and relative risks for elevated anxiety symptoms. RESULTS: Self-reported anxiety symptoms did not significantly differ, although the upper confidence limit (95% CI [-3...
September 16, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28917833/values-based-shared-decision-making-in-the-antenatal-period
#6
REVIEW
Stephanie K Kukora, Renee D Boss
Despite advances in life-saving technology for critically ill neonates, challenges continue to arise for infants delivered with extreme prematurity, congenital anomalies, and genetic conditions that exceed the limits of currently available interventions. In these situations, parents are forced to make cognitively and emotionally difficult decisions, in discussion with a neonatologist, regarding how aggressively to provide supportive measures at the time of delivery and at what point burdens of therapy outweigh benefits...
September 13, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28901997/risk-factors-associated-with-intraventricular-hemorrhage-in-extremely-premature-neonates
#7
Jonathan C Roberts, M Jawad Javed, James R Hocker, Huaping Wang, Michael D Tarantino
: Intraventricular hemorrhage (IVH) is a significant cause of morbidity in extremely premature infants despite many advances in neonatal intensive care. We conducted an institutional retrospective review aimed to correlate risk factors associated with IVH. Clinical variables reported to the Vermont-Oxford Network on less than 30 weeks gestational age infants over a 5-year period were evaluated with Pearson's chi-square and multivariate logistic regression. Of 618 infants born less than 30-week gestational age, 178 (28...
September 8, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28898324/-probiotics-innocuousness-prevention-and-risks
#8
Oscar Brunser
Probiotics have been defined as live microorganisms which, when ingested in adequate numbers, confer health benefits to the host. They are currently consumed without any age restrictions and adverse effects such as sepsis, a marker of the risk of invasion of the bloodstream, are extremely infrequent. However, some health professionals express doubts about probiotics being truly innocuous. This review discusses the incidence of sepsis secondary to probiotics use, mainly lactobacilli and bifidobacteria, evaluated through molecular biology or classic culture techniques, showing that sepsis in large numbers of individuals along decennia is extremely low, of the order of 0,02% en some centers or as low as 1 case/million population in France...
2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28890425/platelet-to-lymphocyte-ratio-a-new-inflammatory-marker-for-the-diagnosis-of-preterm-premature-rupture-of-membranes
#9
Erzat Toprak, Murat Bozkurt, Burcu Dinçgez Çakmak, Emel Ebru Özçimen, Musa Silahlı, Ayşe Ender Yumru, Eray Çalışkan
OBJECTIVE: Preterm premature rupture of membranes (PPROM) is closely related with maternal and fetal complications. Therefore, early diagnosis is extremely important to provide maternal and fetal well-being. Many inflammatory markers have been evaluated for their ability to diagnose membrane rupture at early stages. We aimed to investigate the relationship between the platelet-to-lymphocyte ratio (PLR) and preterm premature membrane rupture. MATERIAL AND METHODS: In this study, 121 pregnant women with PPROM and 96 age-matched pregnant women with spontaneous preterm labor who were admitted to our hospital between January 2014 and December 2015 were enrolled...
September 1, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/28889767/delayed-interval-delivery-in-twin-pregnancies-report-of-three-cases-and-literature-review
#10
Marta Benito Vielba, Carlos De Bonrostro Torralba, Victoria Pallarés Arnal, Rebeca Herrero Serrano, Eva Lucía Tejero Cabrejas, Jose Manuel Campillos Maza
INTRODUCTION: Delayed delivery is sometimes performed in selected multifetal pregnancies when the first twin birth occurs inevitably. The aim of this procedure is to improve the prognosis and decrease the morbidity and mortality of the second twin. We report three cases of delayed-interval delivery of dichorionic-diamniotic twin pregnancies assisted in our center between 2015 and 2017. After the first twin delivery, the second twin was left in utero and the patient received tocolytic therapy and antibiotics...
September 10, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28887016/myotome-adaptability-confers-developmental-robustness-to-somitic-myogenesis-in-response-to-fibre-number-alteration
#11
Shukolpa D Roy, Victoria C Williams, Tapan G Pipalia, Kuoyu Li, Christina L Hammond, Stefanie Knappe, Robert D Knight, Simon M Hughes
Balancing the number of stem cells and their progeny is crucial for tissue development and repair. Here we examine how cell numbers and overall muscle size are tightly regulated during zebrafish somitic muscle development. Muscle stem/precursor cell (MPCs) expressing Pax7 are initially located in the dermomyotome (DM) external cell layer, adopt a highly stereotypical distribution and thereafter a proportion of MPCs migrate into the myotome. Regional variations in the proliferation and terminal differentiation of MPCs contribute to growth of the myotome...
September 5, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28885092/infant-discovery-learning-and-lower-extremity-coordination-influence-of-prematurity
#12
Barbara Sargent, Masayoshi Kubo, Linda Fetters
AIMS: Preterm infants at increased risk for neurodevelopmental disabilities, including cerebral palsy, demonstrate reduced selective leg joint coordination. Full-term infants demonstrate more selective hip-knee coordination when specific leg actions are reinforced using an overhead infant mobile. The purpose of this pilot study was to determine the ability of preterm infants to: (1) perform and learn through discovery, the contingency between leg action and mobile activation, and (2) demonstrate more selective hip-knee coordination when leg actions are reinforced with mobile activation...
September 8, 2017: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/28880261/bronchopulmonary-dysplasia-associated-pulmonary-hypertension-clues-from-placental-pathology
#13
A M Kunjunju, K R Gopagondanahalli, Y Chan, A Sehgal
OBJECTIVES: Bronchopulmonary dysplasia (BPD) and the associated complication of pulmonary hypertension (PH) leads to increased mortality and a longer length of stay among survivors. Placental histopathology may give early clues of subsequent events. The objective was to evaluate the relationship of maternal vascular underperfusion (MVU) changes on placental histopathology with subsequent development of BPD-associated PH in a cohort of extremely premature infants. STUDY DESIGN: In a cohort of preterm infants '⩽28 weeks' gestational age (GA) and with 'severe' BPD, this retrospective study evaluated specific placental histopathological changes and assessed the relationship with subsequent development of PH...
September 7, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28872187/the-attachment-imperative-parental-experiences-of-relation-making-in-a-danish-neonatal-intensive-care-unit
#14
Laura E Navne, Mette N Svendsen, Tine M Gammeltoft
In this article, we explore how parents establish relations with extremely premature infants whose lives and futures are uncertain. Drawing on ethnographic fieldwork in a Danish Neonatal Intensive Care Unit (NICU), we engage recent discussions of the limits of conventional anthropological thinking on social relations and point to the productive aspects of practices of distance and detachment. We show that while the NICU upholds an imperative of attachment independently of the infant's chances of survival, for parents, attachment is contingent on certain hesitations in relation to their infant...
September 4, 2017: Medical Anthropology Quarterly
https://www.readbyqxmd.com/read/28871620/oropharyngeal-surfactant-can-improve-initial-stabilisation-and-reduce-rescue-intubation-in-infants-born-below-25-weeks-of-gestation
#15
Tereza Lamberska, Eva Settelmayerova, Jan Smisek, Marketa Luksova, Gabriela Maloskova, Richard Plavka
AIM: Minimally aggressive and easily performed techniques that facilitate spontaneous respiratory stabilisation are required to reduce rescue intubation in extremely premature infants. This study evaluated the feasibility and safety of administering surfactant into the pharynx of infants born at less than 25 weeks immediately after birth. METHODS: This study of 19 infants was conducted from January 2013 to July 2014 in a tertiary perinatal centre in Prague. We administered 1...
September 4, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28869278/cerebral-near-infrared-spectroscopy-monitoring-for-prevention-of-brain-injury-in-very-preterm-infants
#16
REVIEW
Simon Hyttel-Sorensen, Gorm Greisen, Bodil Als-Nielsen, Christian Gluud
BACKGROUND: Cerebral injury and long-term neurodevelopmental impairment is common in extremely preterm infants. Cerebral near-infrared spectroscopy (NIRS) enables continuous estimation of cerebral oxygenation. This diagnostic method coupled with appropriate interventions if NIRS is out of normal range (that is cerebral oxygenation within the 55% to 85% range) may offer benefits without causing more harms. Therefore, NIRS coupled with appropriate responses to abnormal findings on NIRS needs assessment in a systematic review of randomised clinical trials and quasi-randomised studies...
September 4, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28866372/sutureless-enterostomy-for-extremely-low-birth-weight-infants
#17
Kensuke Ohashi, Tsugumichi Koshinaga, Shuichiro Uehara, Takeshi Furuya, Hide Kaneda, Hiroyuki Kawashima, Taro Ikeda
OBJECTIVE: In recent years, improved survival rates of extremely low birth weight infants (ELBWIs) have led to an increasing number of enterostomy performed for those with meconium obstruction of prematurity (MOP)(1,2), spontaneous intestinal perforation (SIP)(3,4). To prevent serious stoma-related complications such as stoma side perforation, prolapse, fall and surgical site infection, we introduce our new "sutureless enterostomy" technique. METHODS: We present the procedures in detail...
August 15, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28863301/long-term-atmospheric-visibility-trends-in-megacities-of-china-india-and-the-united-states
#18
Yue Hu, Ling Yao, Zhen Cheng, Yungang Wang
Millions of premature deaths worldwide every year mostly in China and India are contributed by the poor air quality. The atmospheric visibility is a proven indicator of the ambient air quality. In this study, nine megacities were selected, including Beijing, Shanghai and Guangzhou from China, Chicago, Los Angeles (LA) and New York City (NYC) from the United States, and Mumbai, Chennai and Jaipur from India. The data of visibility, aerosol optical depth (AOD), and meteorological factors from 1973 to 2015 were collected...
August 29, 2017: Environmental Research
https://www.readbyqxmd.com/read/28861337/clinical-neuroimaging-in-the-preterm-infant-diagnosis-and-prognosis
#19
REVIEW
Manuel Hinojosa-Rodríguez, Thalía Harmony, Cristina Carrillo-Prado, John Darrell Van Horn, Andrei Irimia, Carinna Torgerson, Zachary Jacokes
Perinatal care advances emerging over the past twenty years have helped to diminish the mortality and severe neurological morbidity of extremely and very preterm neonates (e.g., cystic Periventricular Leukomalacia [c-PVL] and Germinal Matrix Hemorrhage - Intraventricular Hemorrhage [GMH-IVH grade 3-4/4]; 22 to < 32 weeks of gestational age, GA). However, motor and/or cognitive disabilities associated with mild-to-moderate white and gray matter injury are frequently present in this population (e.g., non-cystic Periventricular Leukomalacia [non-cystic PVL], neuronal-axonal injury and GMH-IVH grade 1-2/4)...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28859914/there-is-an-association-between-disease-location-and-gestational-age-at-birth-in-newborns-submitted-to-surgery-due-to-necrotizing-enterocolitis
#20
Letícia Feldens, João C K de Souza, José C Fraga
AIMS: To evaluate if there are differences regarding disease location and mortality of necrotizing enterocolitis, according to the gestational age at birth, in newborns submitted to surgery due to enterocolite. METHODS: A historical cohort study of 198 newborns submitted to surgery due to necrotizing enterecolitis in a tertiary hospital, from November 1991 to December 2012. The newborns were divided into different categories according to gestational age (<30 weeks, 30-33 weeks and 6 days, 34-36 weeks and 6 days, and ≥37 weeks), and were followed for 60 days after surgery...
August 30, 2017: Jornal de Pediatria
keyword
keyword
25301
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"