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https://www.readbyqxmd.com/read/27932268/ten-principles-for-a-safe-surgical-treatment-of-ovarian-endometriosis
#1
M A López-de la Torre, H M Abrao, L F Fernandes, R M Kho, M S Abrao
OBJECTIVE: To demonstrate a step-by-step laparoscopic approach for excision of ovarian endometrioma following surgical principles for safety and maximal preservation of ovarian function. DESIGN: Video SETTING: Medical management of ovarian endometriomas is not recommended. Operative laparoscopic is the treatment of choice. Although considered a simple procedure, ovarian cystectomy requires precise and correct technique in order to preserve ovarian function. PATIENT: Asymptomatic, 27yo woman with ultrasound imaging suggesting a 6,2 x 5,4 cm left endometrioma...
December 5, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27930913/self-management-in-young-adults-with-bipolar-disorder-strategies-and-challenges
#2
Jennifer Nicholas, Katherine Boydell, Helen Christensen
BACKGROUND: Early adoption of effective self-management strategies for bipolar disorder (BD) results in better clinical outcomes and increased quality of life. Therefore, facilitation of these strategies in young adults who are early in their illness course is vital. However, an understanding of self-management practices and needs of young adults with BD is lacking. This study explores young adult's perspectives of disorder self-management practices and challenges. METHODS: Young adults with BD completed an online survey about disorder management strategies and challenges...
November 29, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27930603/strategies-to-improve-the-efficacy-of-epicardial-linear-ablation-on-the-beating-heart
#3
Yoshiyuki Watanabe, Matthew R Schill, Toshinobu Kazui, Spencer J Melby, Richard B Schuessler, Ralph J Damiano
OBJECTIVE: Creating transmural linear lesions on the beating heart is an important component of minimally invasive surgical ablation for atrial fibrillation. Animal studies have shown poor efficacy for surface bipolar radiofrequency ablation (RFA). Clinicians have developed strategies including multiple device applications and vena caval occlusion (VCO) to improve ablation efficacy. These techniques were evaluated in an acute porcine model. METHODS: In the first experiment, an RFA device was used to perform two 40-second epicardial ablations on the right atrium of six pigs...
December 7, 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27930497/the-comt-val158met-polymorphism-is-associated-with-response-to-add-on-dextromethorphan-treatment-in-bipolar-disorder
#4
Sheng-Yu Lee, Shiou-Lan Chen, Tzu-Yun Wang, Yun-Hsuan Chang, Po See Chen, San-Yuan Huang, Nian-Sheng Tzeng, Liang-Jen Wang, I Hui Lee, Kao Ching Chen, Yen Kuang Yang, Ru-Band Lu
PURPOSE/BACKGROUND: We previously conducted a randomized, double-blind, controlled, 12-week study evaluating the effect of add-on dextromethorphan (DM), a noncompetitive N-methyl-D-aspartate receptor antagonist, on patients with bipolar disorder (BD) treated using valproate (VPA), which showed negative clinical differences. The genetic variation between each individual may be responsible for interindividual differences. The catechol-O-methyltransferase (COMT) gene has been a candidate gene for BD...
December 7, 2016: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/27929612/effects-of-cumulative-herpesviridae-and-toxoplasma-gondii-infections-on-cognitive-function-in-healthy-bipolar-and-schizophrenia-subjects
#5
Nora Hamdani, Claire Daban-Huard, Ophelia Godin, Hakim Laouamri, Stéphane Jamain, Dodji Attiba, Marine Delavest, Jean-Pierre Lépine, Philippe Le Corvoisier, Josselin Houenou, Jean-Romain Richard, Robert H Yolken, Rajagopal Krishnamoorthy, Ryad Tamouza, Marion Leboyer, Faith B Dickerson
OBJECTIVE: Schizophrenia and bipolar disorder are associated with cognitive impairment leading to social disruption. While previous studies have focused on the effect of individual infectious exposure, namely, Herpesviridae viruses or Toxoplasma gondii (T gondii), on cognitive functioning, the objective of the present study was to examine the effect of multiple infections on cognitive functioning in patients with schizophrenia and bipolar disorder and in healthy controls. METHODS: Seropositivity to herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), cytomegalovirus (CMV), and T gondii was related to cognitive status among 423 participants (recruited between 2008 and 2014; 138 patients with bipolar disorder, 105 patients with schizophrenia [DSM-IV criteria], and 180 healthy controls) for episodic verbal memory (California Verbal Learning Test), working memory (Wechsler Adult Intelligence Scale, third edition), and premorbid intelligence quotient (National Adult Reading Test)...
December 6, 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27928249/%C3%A2-recurrence-in-patients-with-bipolar-disorder-and-its-risk-factors
#6
Roya Najafi-Vosough, Ali Ghaleiha, Javad Faradmal, Hossein Mahjub
Objective: The aim of this study was to identify prognosis factors associated with recurrence in patients ‎with bipolar disorder.‎‎ Method: This retrospective cohort study was conducted in Hamadan Province, the west of Iran. All ‎patients (n = 400) with bipolar disorder who were hospitalized for the second time or more ‎during April 2008 to September 2014 were included in this study. Ordinal logistic regression ‎analysis was employed to determine the effective factors in each recurrence, and odds ratio (OR) and 95% confidence intervals (CI) were obtained...
July 2016: Iranian Journal of Psychiatry
https://www.readbyqxmd.com/read/27927846/risk-of-postpartum-psychosis-after-ivf-treatment-a-nationwide-case-control-study
#7
Josefin Vikström, Ann Josefsson, Mats Hammar, Marie Bladh, Gunilla Sydsjö
STUDY QUESTION: Is the risk of postpartum psychosis (PPP) increased in women who give birth after IVF treatment compared to after spontaneous conception? SUMMARY ANSWER: The risk of PPP is not higher in the group of women who give birth after IVF treatment compared with women who give birth after spontaneous conception. WHAT IS KNOWN ALREADY: Women who conceive using IVF treatment can experience higher levels of pregnancy-specific distress and are at increased risk of pre-eclampsia, an immune-related condition which in turn has been linked to PPP, as well as other pregnancy and delivery complications, which also serve as PPP risk factors...
December 6, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27924149/differences-in-real-world-executive-function-between-children-with-pediatric-bipolar-disorder-and-children-with-adhd
#8
Alessandra M Passarotti, Nidhi Trivedi, Liza Dominguez-Colman, Manharkumar Patel, Scott A Langenecker
BACKGROUND: Recent research evidence suggests that executive function (EF) is impaired in both pediatric bipolar disorder (PBD) and attention deficit-hyperactivity disorder (ADHD), although the underlying cognitive mechanisms are still unclear. In this study we examined EF, including cognitive and emotional control, in three pediatric groups with overlapping symptoms. METHODS: Sixteen children and adolescents with PBD, 17 children and adolescents with ADHD, Type Combined, and 13 children and adolescents with PBD and comorbid ADHD (PBD+ADHD) (mean age=12...
2016: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/27922594/cacna1c-in-the-prefrontal-cortex-regulates-depression-related-behaviors-via-redd1
#9
Zeeba D Kabir, Anni S Lee, Caitlin E Burgdorf, Delaney Fischer, Aditi M Rajadhyaksha, Ethan Mok, Bryant Rizzo, Richard C Rice, Kamalpreet Singh, Kristie T Ota, Danielle M Gerhard, Kathryn C Schierberl, Michael Glass, Ronald S Duman, Anjali M Rajadhyaksha
The CACNA1C gene that encodes the L-type Ca(2+) channel (LTCC) Cav1.2 subunit has emerged as a candidate risk gene for multiple neuropsychiatric disorders including bipolar disorder, major depressive disorder and schizophrenia, all marked with depression-related symptoms. Although cacna1c heterozygous (HET) mice have been previously reported to exhibit an antidepressant-like phenotype, the molecular and circuit-level dysfunction remains unknown. Here we report that viral vector-mediated deletion of cacna1c in the adult prefrontal cortex (PFC) of mice recapitulates the antidepressant-like effect observed in cacna1c HET mice using the sucrose preference test (SPT), the forced swim test (FST), and the tail suspension test (TST)...
December 6, 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27921187/rotor-tracking-using-phase-of-electrograms-recorded-during-atrial-fibrillation
#10
Caroline H Roney, Chris D Cantwell, Norman A Qureshi, Rasheda A Chowdhury, Emmanuel Dupont, Phang Boon Lim, Edward J Vigmond, Jennifer H Tweedy, Fu Siong Ng, Nicholas S Peters
Extracellular electrograms recorded during atrial fibrillation (AF) are challenging to interpret due to the inherent beat-to-beat variability in amplitude and duration. Phase mapping represents these voltage signals in terms of relative position within the cycle, and has been widely applied to action potential and unipolar electrogram data of myocardial fibrillation. To date, however, it has not been applied to bipolar recordings, which are commonly acquired clinically. The purpose of this study is to present a novel algorithm for calculating phase from both unipolar and bipolar electrograms recorded during AF...
December 5, 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/27919751/less-head-motion-during-mri-under-task-than-resting-state-conditions
#11
Willem Huijbers, Koene R A Van Dijk, Meta M Boenniger, Rüdiger Stirnberg, Monique M B Breteler
Head motion reduces data quality of neuroimaging data. In three functional magnetic resonance imaging (MRI) experiments we demonstrate that people make less head movements under task than resting-state conditions. In Experiment 1, we observed less head motion during a memory encoding task than during the resting-state condition. In Experiment 2, using publicly shared data from the UCLA Consortium for Neuropsychiatric Phenomics LA5c Study, we again found less head motion during several active task conditions than during a resting-state condition, although some task conditions also showed comparable motion...
December 2, 2016: NeuroImage
https://www.readbyqxmd.com/read/27918826/long-term-protection-of-genetically-ablated-rabbit-retinal-degeneration-by-sustained-transscleral-unoprostone-delivery
#12
Nobuhiro Nagai, Eri Koyanagi, Yasuko Izumida, Junjun Liu, Aya Katsuyama, Hirokazu Kaji, Matsuhiko Nishizawa, Noriko Osumi, Mineo Kondo, Hiroko Terasaki, Yukihiko Mashima, Toru Nakazawa, Toshiaki Abe
Purpose: To evaluate the long-term protective effects of transscleral unoprostone (UNO) against retinal degeneration in transgenic (Tg) rabbits (Pro347Leu rhodopsin mutation). Methods: The UNO release devices (URDs) were implanted into the sclerae of Tg rabbits and ERG, optical coherence tomography (OCT), and ophthalmic examinations were conducted for 40 weeks. Unoprostone metabolites in retina, choroid/RPE, aqueous humor, and plasma from wild-type (Wt) rabbits were measured using liquid chromatography-tandem mass spectrometry...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27916665/task-modulations-and-clinical-manifestations-in-the-brain-functional-connectome-in-1615-fmri-datasets
#13
Tobias Kaufmann, Dag Alnæs, Christine Lycke Brandt, Nhat Trung Doan, Karolina Kauppi, Francesco Bettella, Trine V Lagerberg, Akiah O Berg, Srdjan Djurovic, Ingrid Agartz, Ingrid S Melle, Torill Ueland, Ole A Andreassen, Lars T Westlye
OBJECTIVE: An abundance of experimental studies have motivated a range of models concerning the cognitive underpinnings of severe mental disorders, yet the conception that cognitive and brain dysfunction is confined to specific cognitive domains and contexts has limited ecological validity. Schizophrenia and bipolar spectrum disorders have been conceptualized as disorders of brain connectivity; yet little is known about the pervasiveness across cognitive tasks. METHOD: To address this outstanding issue of context specificity, we estimated functional network connectivity from fMRI data obtained during five cognitive tasks (0-back, 2-back, go/no-go, recognition of positive faces, negative faces) in 90 patients with schizophrenia, 97 patients with bipolar spectrum disorder, and 136 healthy controls, including 1615 fMRI datasets in total...
December 1, 2016: NeuroImage
https://www.readbyqxmd.com/read/27913259/-postoperative-delayed-paradoxical-depression-pdpd-after-uncomplicated-intracranial-aneurysm-surgery
#14
Tomas Garzon-Muvdi, Wuyang Yang, Andrew S Luksik, Alejandro Ruiz-Valls, Rafael John Tamargo, Justin Caplan, Rafael J Tamargo
BACKGROUND: Postoperative delayed paradoxical depression (PDPD) is a psychiatric condition described in patients who undergo a major surgery without complications, do not have a history of mood disorders, but nevertheless become clinically depressed. PDPD has been recognized in major surgical interventions such as coronary artery bypass surgery. We sought to determine the incidence and potential factors associated with PDPD after surgical treatment of intracranial aneurysms. METHODS: The cohort of 105 patients was derived from a prospective observational dataset of 3788 consecutive cases of intracranial aneurysms accrued from 1991-2015...
November 29, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27911454/steady-state-acetabular-cartilage-wear-after-bipolar-hemiarthroplasty-a-case-series-of-10-patients-with-radiostereometric-analysis
#15
Masako Tsukanaka, Ragnhild Ø Støen, Wender Figved, Frede Frihagen, Lars Nordsletten, Stephan M Röhrl
INTRODUCTION: Cartilage wear is a concern after hemiarthroplasty. The precise pattern of the progression of wear has not been evaluated. We previously reported the application of radiostereonetric analysis (RSA) for the measurement of cartilage wear in patients. The purpose of this study was to report the amount and the orientation of the steady state wear of cartilage between 1 and 3 years after bipolar hemiarthroplasty. METHODS: 22 patients with a bipolar hemiarthroplasty for displaced femoral neck fracture were included...
December 2, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27911003/current-psychotropic-medication-prescribing-patterns-in-late-life-bipolar-disorder
#16
Soham Rej, Nathan Herrmann, Kenneth Shulman, Hadas D Fischer, Kinwah Fung, Andrea Gruneir
OBJECTIVE: Many patients with bipolar disorder are reaching old age, but whether they are receiving evidence-based psychotropic treatment remains unclear. Our objective was to describe current psychotropic prescribing patterns in a large Canadian late-life bipolar sample. METHODS: Population-based cross-sectional study of 1443 bipolar disorder patients aged ≥ 66, discharged from a psychiatric hospitalization in Ontario, Canada from 1 April 2006 to 31 March 2012...
December 2, 2016: International Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/27910921/bipolar-and-unipolar-silylene-diphenylene-%C3%AF-%C3%AF-conjugated-polymer-route-for-highly-efficient-electrophosphorescence
#17
Yao-Tang Chang, Sunil Sharma, Miao-Ken Hung, Yu-Hsuan Lee, Show-An Chen
σ-π conjugated polymer strategy is proposed for designing electroluminescent host polymers with silylene-diphenylene as the backbone repeat unit giving a high triplet energy (ET = 2.67 eV). By incorporation of high ET (3.0 eV) electron (oxadiazole, OXD) and hole (triphenyl amine, TPA) transport moieties, or TPA alone (in this case, the main chain acts as electron transport channel) as side arms on the silylene, the high ET bipolar and unipolar polymers are formed, allowing a use of iridium green phosphor (Ir(ppy)2(acac), Ir-G) (ET = 2...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27909826/profile-and-determinants-of-disability-in-psychotic-disorders-in-nigeria
#18
Victor Olufolahan Lasebikan, Olatunde Ayinde
We compared profile and predictors of disability among 210 patients with schizophrenia, schizoaffective disorder, bipolar I disorder with psychosis and depression with psychosis, respectively in a Nigerian clinical population, using the WHO Disability Assessment Schedule, (2.0). Severity of psychosis was determined with Positive and Negative Symptoms Scale, functioning was assessed using the Global Assessment of Functioning Scale, medication adherence with the Medication Adherence Questionnaire. Analyses were by SPSS 20...
December 1, 2016: Community Mental Health Journal
https://www.readbyqxmd.com/read/27908173/pacemaker-and-icd-oversensing-induced-by-movements-near-the-mri-scanner-bore
#19
E Mattei, F Censi, G Calcagnini, R Falsaperla, E Genovese, A Napolitano, V Cannatà
PURPOSE: The effect of the movement near the MRI scanner bore for people with a pacemaker (PM) or an implantable cardioverter defibrillator (ICD) is experimentally evaluated and discussed. METHODS: The authors performed in vitro measurements on a saline-filled human-shaped phantom (male, 170 cm height), equipped first with an MR-conditional PM (bicameral configuration, DDD programming), then with an MR-conditional ICD (biventricular configuration, detection algorithms enable but shock delivery disable)...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27905499/the-correlation-between-plasma-brain-derived-neurotrophic-factor-and-cognitive-function-in-bipolar-disorder-is-modulated-by-the-bdnf-val66met-polymorphism
#20
Sheng-Yu Lee, Tzu-Yun Wang, Shiou-Lan Chen, Yun-Hsuan Chang, Po-See Chen, San-Yuan Huang, Nian-Sheng Tzeng, Liang-Jen Wang, I Hui Lee, Kao Chin Chen, Yen Kuang Yang, Yi-Hsin Yang, Ru-Band Lu, Cheng-Sheng Chen
We explored the effect of the Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism (rs6265) on correlation between changes in plasma BDNF levels with cognitive function and quality of life (QoL) after 12 weeks of treatment in bipolar disorder (BD). Symptom severity and plasma BDNF levels were assessed upon recruitment and during weeks 1, 2, 4, 8 and 12. QoL, the Wisconsin Card Sorting Test (WCST), and the Conners' Continuous Performance Test (CPT) were assessed at baseline and endpoint. The BDNF Val66Met polymorphism was genotyped...
December 1, 2016: Scientific Reports
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