Kjersti Eline Stige, Simon Ulvenes Kverneng, Soumya Sharma, Geir-Olve Skeie, Erika Sheard, Mona Søgnen, Solveig Af Geijerstam, Therese Vetås, Anne Grete Wahlvåg, Haakon Berven, Sagar Buch, David Reese, Dina Babiker, Yekta Mahdi, Trevor Wade, Gala Prado Miranda, Jacky Ganguly, Yokhesh Krishnasamy Tamilselvam, Jia Ren Chai, Saurabh Bansal, Dorian Aur, Sima Soltani, Scott Adams, Christian Dölle, Fiona Dick, Erik Magnus Berntsen, Renate Grüner, Njål Brekke, Frank Riemer, Pål Erik Goa, Kristoffer Haugarvoll, E Mark Haacke, Mandar Jog, Charalampos Tzoulis
The STRAT-PARK initiative aims to provide a platform for stratifying Parkinson's disease (PD) into biological subtypes, using a bottom-up, multidisciplinary biomarker-based and data-driven approach. PD is a heterogeneous entity, exhibiting high interindividual clinicopathological variability. This diversity suggests that PD may encompass multiple distinct biological entities, each driven by different molecular mechanisms. Molecular stratification and identification of disease subtypes is therefore a key priority for understanding and treating PD...
April 9, 2024: Progress in Neurobiology