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https://www.readbyqxmd.com/read/27913557/translation-and-validation-of-the-cancer-related-fatigue-scale-in-greek-in-a-sample-of-patients-with-advanced-prostate-cancer
#1
Andreas Charalambous, Charis Kaite, Marianna Constantinou, Christiana Kouta
OBJECTIVE: To translate and validate the Cancer-Related Fatigue (CRF) Scale in the Greek language. DESIGN: A cross-sectional descriptive design was used in order to translate and validate the CRF Scale in Greek. Factor analyses were performed to understand the psychometric properties of the scale and to establish construct, criterion and convergent validity. SETTING: Outpatients' oncology clinics of two public hospitals in Cyprus. PARTICIPANTS: 148 patients with advanced prostate cancer undergoing chemotherapy...
December 2, 2016: BMJ Open
https://www.readbyqxmd.com/read/27913407/whole-brain-analysis-reveals-increased-neuroanatomical-asymmetries-in-dementia-for-hippocampus-and-amygdala
#2
Christian Wachinger, David H Salat, Michael Weiner, Martin Reuter
Structural magnetic resonance imaging data are frequently analysed to reveal morphological changes of the human brain in dementia. Most contemporary imaging biomarkers are scalar values, such as the volume of a structure, and may miss the localized morphological variation of early presymptomatic disease progression. Neuroanatomical shape descriptors, however, can represent complex geometric information of individual anatomical regions and may demonstrate increased sensitivity in association studies. Yet, they remain largely unexplored...
December 2016: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/27913095/soft-hard-tissues-and-pharyngeal-airway-volume-changes-following-maxillomandibular-transverse-osteodistraction-computed-tomography-and-three-dimensional-laser-scanner-evaluation
#3
Francesca Antonella Bianchi, Giovanni Gerbino, Marina Corsico, Eleonora Schellino, Niccolò Barla, Laura Verzè, Guglielmo Ramieri
INTRODUCTION: Maxillomandibular transverse osteodistraction (MMTOD) is an alternative approach to the traditional treatment for transverse maxillary and mandibular deficiencies and crowding. The aim was to report soft and hard-tissues changes and airway volume variation. METHODS: In this study, skeletally mature, non-syndromic patients with transverse maxillary and mandibular hypoplasia, who underwent a MMTOD between 2010 and 2012, were included. Surgical changes were analysed using clinical evaluation, three-dimensional facial surface data and computed tomography analysis before (T0) and after the completion of post-op orthodontic treatment (T1)...
October 18, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27911751/the-lateral-habenula-circuitry-reward-processing-and-cognitive-control
#4
Phillip M Baker, Thomas Jhou, Bo Li, Masayuki Matsumoto, Sheri J Y Mizumori, Marcus Stephenson-Jones, Aleksandra Vicentic
There has been a growing interest in understanding the role of the lateral habenula (LHb) in reward processing, affect regulation, and goal-directed behaviors. The LHb gets major inputs from the habenula-projecting globus pallidus and the mPFC, sending its efferents to the dopaminergic VTA and SNc, serotonergic dorsal raphe nuclei, and the GABAergic rostromedial tegmental nucleus. Recent studies have made advances in our understanding of the LHb circuit organization, yet the precise mechanisms of its involvement in complex behaviors are largely unknown...
November 9, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27910103/reliability-and-concurrent-validity-of-a-new-iphone-%C3%A2-goniometric-application-for-measuring-active-wrist-range-of-motion-a-cross-sectional-study-in-asymptomatic-subjects
#5
Mohammad Reza Pourahmadi, Ismail Ebrahimi Takamjani, Javad Sarrafzadeh, Mehrdad Bahramian, Mohammad Ali Mohseni-Bandpei, Fatemeh Rajabzadeh, Morteza Taghipour
Measurement of wrist range of motion (ROM) is often considered to be an essential component of wrist physical examination. The measurement can be carried out through various instruments such as goniometers and inclinometers. Recent smartphones have been equipped with accelerometers and magnetometers, which, through specific software applications (apps) can be used for goniometric functions. This study, for the first time, aimed to evaluate the reliability and concurrent validity of a new smartphone goniometric app (Goniometer Pro©) for measuring active wrist ROM...
December 2, 2016: Journal of Anatomy
https://www.readbyqxmd.com/read/27909880/il-9-producing-cells-in-the-development-of-ige-mediated-food-allergy
#6
REVIEW
Dana Shik, Sunil Tomar, Jee-Boong Lee, Chun-Yu Chen, Andrew Smith, Yui-Hsi Wang
Food allergy is a harmful immune reaction driven by uncontrolled type 2 immune responses. Considerable evidence demonstrates the key roles of mast cells, IgE, and TH2 cytokines in mediating food allergy. However, this evidence provides limited insight into why only some, rather than all, food allergic individuals are prone to develop life-threatening anaphylaxis. Clinical observations suggest that patients sensitized to food through the skin early in life may later develop severe food allergies. Aberrant epidermal thymic stromal lymphopoietin and interleukin (IL) 33 production and genetic predisposition can initiate an allergic immune response mediated by dendritic cells and CD4(+)TH2 cells in inflamed skin...
December 1, 2016: Seminars in Immunopathology
https://www.readbyqxmd.com/read/27908672/forensic-age-estimation-in-anti-piracy-trials-in-seychelles-experiences-and-challenges-faced
#7
S A Gunawardena, U A Liyanage, J B Weeratna, N D N A Mendis, H J M Perera, R W Jayasekara, R Fernando
Forensic age estimation (FAE) was conducted using a multifactorial method on thirteen Somali detainees claiming juvenile status during the anti-piracy trials of the Seychelles Supreme Court in 2014/2015. A multidisciplinary team, comprising of four of the authors covering specialties in forensic medicine, forensic odontology and radiology, conducted the FAE using a five-stage protocol. Each detainee was interviewed with an interpreter and examined for disorders affecting dental/skeletal development and for assessment of genital development through Tanner staging...
November 14, 2016: Forensic Science International
https://www.readbyqxmd.com/read/27908151/technical-note-a-direct-ray-tracing-method-to-compute-integral-depth-dose-in-pencil-beam-proton-radiography-with-a-multilayer-ionization-chamber
#8
Paolo Farace, Roberto Righetto, Sylvain Deffet, Arturs Meijers, Francois Vander Stappen
PURPOSE: To introduce a fast ray-tracing algorithm in pencil proton radiography (PR) with a multilayer ionization chamber (MLIC) for in vivo range error mapping. METHODS: Pencil beam PR was obtained by delivering spots uniformly positioned in a square (45 × 45 mm(2) field-of-view) of 9 × 9 spots capable of crossing the phantoms (210 MeV). The exit beam was collected by a MLIC to sample the integral depth dose (IDDMLIC). PRs of an electron-density and of a head phantom were acquired by moving the couch to obtain multiple 45 × 45 mm(2) frames...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27908082/objective-and-perceptual-evaluation-of-distance-dependent-scattered-sound-effects-in-a-small-variable-acoustics-hall
#9
Louena Shtrepi, Arianna Astolfi, Gianluca D'Antonio, Martin Guski
Performance spaces are characterized by a complex sound field, due to the presence of absorptive and diffusive surfaces. In situ evaluations of the acoustic effects that these surfaces have on the objective acoustic parameters and on sound perception have not yet been fully understood. To this aim, acoustic measurements have been performed in a variable-acoustic concert hall, the Espace de Projection, at the Institut de Recherche et Coordination Acoustique/Musique. These measurements have allowed the effects of one single wall to be determined...
November 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/27907825/seeing-light-at-the-end-of-the-tunnel-positive-prospective-mental-imagery-and-optimism-in-depression
#10
Julie L Ji, Emily A Holmes, Simon E Blackwell
Optimism is associated with positive outcomes across many health domains, from cardiovascular disease to depression. However, we know little about cognitive processes underlying optimism in psychopathology. The present study tested whether the ability to vividly imagine positive events in one's future was associated with dispositional optimism in a sample of depressed adults. Cross-sectional and longitudinal analyses were conducted, using baseline (all participants, N=150) and follow-up data (participants in the control condition only, N=63) from a clinical trial (Blackwell et al...
November 21, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27907154/pheromone-recognition-and-selectivity-by-comr-proteins-among-streptococcus-species
#11
Erin Shanker, Donald A Morrison, Antoine Talagas, Sylvie Nessler, Michael J Federle, Gerd Prehna
Natural transformation, or competence, is an ability inherent to bacteria for the uptake of extracellular DNA. This process is central to bacterial evolution and allows for the rapid acquirement of new traits, such as antibiotic resistance in pathogenic microorganisms. For the Gram-positive bacteria genus Streptococcus, genes required for competence are under the regulation of quorum sensing (QS) mediated by peptide pheromones. One such system, ComRS, consists of a peptide (ComS) that is processed (XIP), secreted, and later imported into the cytoplasm, where it binds and activates the transcription factor ComR...
December 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27907086/stcdpk3-phosphorylates-in-vitro-two-transcription-factors-involved-in-ga-and-aba-signaling-in-potato-strsg1-and-stabf1
#12
Carolina Grandellis, Elisa Fantino, María Noelia Muñiz García, Magalí Graciela Bialer, Franco Santin, Daniela Andrea Capiati, Rita María Ulloa
Calcium-dependent protein kinases, CDPKs, decode calcium (Ca2+) transients and initiate downstream responses in plants. In order to understand how CDPKs affect plant physiology, their specific target proteins must be identified. In tobacco, the bZIP transcription factor Repression of Shoot Growth (NtRSG) that modulates gibberellin (GA) content is a specific target of NtCDPK1. StCDPK3 from potato is homologous (88% identical) to NtCDPK1 even in its N-terminal variable domain. In this work, we observe that NtRSG is also phosphorylated by StCDPK3...
2016: PloS One
https://www.readbyqxmd.com/read/27907080/development-of-an-automated-mri-based-diagnostic-protocol-for-amyotrophic-lateral-sclerosis-using-disease-specific-pathognomonic-features-a-quantitative-disease-state-classification-study
#13
Christina Schuster, Orla Hardiman, Peter Bede
BACKGROUND: Despite significant advances in quantitative neuroimaging, the diagnosis of ALS remains clinical and MRI-based biomarkers are not currently used to aid the diagnosis. The objective of this study is to develop a robust, disease-specific, multimodal classification protocol and validate its diagnostic accuracy in independent, early-stage and follow-up data sets. METHODS: 147 participants (81 ALS patients and 66 healthy controls) were divided into a training sample and a validation sample...
2016: PloS One
https://www.readbyqxmd.com/read/27904215/morphometry-of-distal-end-radius-in-the-indian-population-a-radiological-study
#14
Pankaj Kumar Mishra, Manoj Nagar, Suresh Chandra Gaur, Anuj Gupta
INTRODUCTION: The morphometry of distal end radius (DER) comprises the four necessary parameters: radial inclination, palmer tilt, radial height, and ulnar variance. The unblemished intellect about the morphometry is urged for the management of fracture of DER. The goal of our study was to determine the values of morphometric parameters of the DER from the adult Indian. MATERIALS AND METHODS: It was a single hospital- based observational cross-sectional, prospective study...
November 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27902687/limb-bone-structural-proportions-and-locomotor-behavior-in-a-l-288-1-lucy
#15
Christopher B Ruff, M Loring Burgess, Richard A Ketcham, John Kappelman
While there is broad agreement that early hominins practiced some form of terrestrial bipedality, there is also evidence that arboreal behavior remained a part of the locomotor repertoire in some taxa, and that bipedal locomotion may not have been identical to that of modern humans. It has been difficult to evaluate such evidence, however, because of the possibility that early hominins retained primitive traits (such as relatively long upper limbs) of little contemporaneous adaptive significance. Here we examine bone structural properties of the femur and humerus in the Australopithecus afarensis A...
2016: PloS One
https://www.readbyqxmd.com/read/27902374/structures-and-serospecificity-of-threonine-containing-o-polysaccharides-of-two-clinical-isolates-belonging-to-the-genus-proteus-and-their-classification-into-o11-subserogroups
#16
Dominika Drzewiecka, Nikolay P Arbatsky, Anna N Kondakova, Alexander S Shashkov, Yuriy A Knirel
Two clinical isolates from Polish patients, Proteus mirabilis 9B-m and Proteus genomospecies 3J-r, were found to be serologically related to P mirabilis O11. However, serological studies involving ELISA and Western blotting methods, using lipopolysaccharides (LPSs) extracted from the strains as antigens and native or adsorbed rabbit polyclonal O antisera, specific to the studied strains, revealed slight differences in the cross-reactivity and specificity of the two studied Proteus isolates, when compared to P...
November 2016: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/27901627/effects-of-pediatric-asthma-care-coordination-in-underserved-communities-on-parent-perceptions-of-care-and-asthma-management-confidence
#17
Mary R Janevic, Alan P Baptist, Tyra Bryant-Stephens, Marielena Lara, Victoria Persky, Gilberto Ramos-Valencia, Kimberly Uyeda, Rebecca Hazan, Ashley Garrity, Floyd J Malveaux
OBJECTIVE: Disparities by race and socioeconomic status persist in pediatric asthma morbidity, mortality, and treatment. Improving parent/provider communication and parents' asthma-management confidence may result in better asthma control in vulnerable populations. The Merck Childhood Asthma Network, Inc. funded an initiative to implement medical-social care coordination to improve asthma outcomes at sites in four low-income, urban communities (Los Angeles, CA; Philadelphia, PA; Chicago, IL; and San Juan, PR...
November 30, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27901231/the-duration-of-pubertal-growth-peak-among-three-skeletal-classes
#18
Waqar Jeelani, Mubassar Fida, Attiya Shaikh
Introduction: Pubertal growth peak is closely associated with a rapid increase in mandibular length and offers a wide range of therapeutic modifiability. Objective: The aim of the present study was to determine and compare the mean ages of onset and duration of pubertal growth peak among three skeletal classes. Methods: A retrospective cross-sectional study was conducted using lateral cephalograms of 230 subjects with growth potential (110 males, 120 females)...
September 2016: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/27901084/development-of-mouthparts-in-the-cicada-meimuna-mongolica-distant-successive-morphological-patterning-and-sensilla-differentiation-from-nymph-to-adult
#19
Yanan Hao, Christopher H Dietrich, Wu Dai
Development of the mouthparts in the cicada Meimuna mongolica (Distant) is investigated here for the first time using scanning electron microscopy in order to document changes occurring in different nymphal instars and from nymph to adult, during which a shift from subterranean root-feeding to feeding on aboveground parts of the host plant occurs. The structure and component of mouthparts is similar to those found in other hemipteran insects. Fourteen types of sensilla and five types of cuticular processes were found on the mouthparts of nymphs and adults...
November 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27900196/muscle-function-is-associated-with-future-patient-reported-outcomes-in-young-adults-with-acl-injury
#20
Vala Flosadottir, Ewa M Roos, Eva Ageberg
BACKGROUND/AIM: Consequences of an anterior cruciate ligament (ACL) injury include worse patient-reported outcomes (PROs) and a decrease in activity level. Muscle function can be improved by targeted exercise. Our aims were to investigate cross-sectional and longitudinal associations among lower extremity muscle function and PROs after ACL injury. METHODS: Fifty-four participants (15 women, mean 30 years) with ACL injury or reconstruction, from the Knee Anterior Cruciate Ligament, Nonsurgical versus Surgical Treatment (KANON) trial (ISRCTN84752559), were assessed with hop performance, muscle power and postural orientation 3 years (SD 0...
2016: BMJ Open Sport & Exercise Medicine
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