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Pediatric swallowing

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https://www.readbyqxmd.com/read/28229065/foreign-body-aspiration-in-adults-two-unusual-foreign-bodies-knife-and-tube-tracheostomy
#1
Seyed Mozafar Hashemi, Mohsen Kolahdouzan, Shahab Shahabi, Hamid Talebzadeh, Mohammad Taghi Rezaei
INTRODUCTION: Foreign body aspiration is usually a serious condition that is most common among the pediatric population, and rare in adults. In adults, aspiration may be tolerated for a long time. CASE REPORTS: Our first case is a 38-year-old man who presented with a 2-day history of swallowing a foreign body. He was completely asymptomatic. Chest X-ray revealed the presence of 5-cm foreign object in the right main bronchus. Rigid bronchoscopy was performed and a knife was removed from the right main bronchus...
January 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28180149/the-obalon-swallowable-intragastric-balloon-in-pediatric-and-adolescent-morbid-obesity
#2
Francesco De Peppo, Romina Caccamo, Ottavio Adorisio, Emanuela Ceriati, Paola Marchetti, Antonio Contursi, Arianna Alterio, Claudia Della Corte, Malnia Manco, Valerio Nobili
Background and study aims Incidence of morbid obesity has grown dramatically in the last half century and this phenomenon affects with particular severity the pediatric population. Dietary restrictions and careful programs to improve lifestyle are often ineffective to manage this particular group of patients, due to poor compliance typical of the adolescence. The aim of this study was to evaluate the effectiveness of a new intragastric balloon for treatment of morbidly obese children. Patients and methods A new swallowable intragastric balloon (Obalon) has been used for the first time in 17 obese children in order to assess its safety and effectiveness in terms of reduction in excess weight...
January 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28138820/development-of-extended-release-oral-flexible-tablet-er-oft-formulation-for-pediatric-and-geriatric-compliance-an-age-appropriate-formulation
#3
Prabagaran Chandrasekaran, Ruckmani Kandasamy
Development of age-appropriate formulation suitable for pediatric and geriatric patients involves various challenges. The objective of this research was to develop extended-release oral flexible tablet (ER-OFT) formulation using carbamazepine (CBZ) as model drug for pediatric and geriatric compliance. ER-microparticles of carbamazepine, a BCS class 2, and narrow therapeutic index (NTI) drug, were prepared using ethyl cellulose as matrixing polymer and hypromellose as hydrophilic pore former. Microparticles were prepared using high-shear granulator fitted with an atomizing spray system...
January 30, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28109495/swallowing-function-in-pediatric-patients-with-bilateral-vocal-fold-immobility
#4
Jeffrey Hsu, Kathleen M Tibbetts, Derek Wu, Michel Nassar, Melin Tan
INTRODUCTION: Infants with bilateral vocal fold immobility (BVFI) often have poor swallow function in addition to potential airway compromise. While there are several reports on BVFI and its effect on patients' airway status, little is known about long term swallow function. OBJECTIVES: We aim to characterize the swallowing function over time in pediatric patients with bilateral vocal fold immobility. METHODS: A retrospective review of medical records of infants diagnosed with BVFI at a tertiary care children's hospital between 2005 and 2014 was conducted...
February 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28090779/preparation-and-in-vitro-in-vivo-evaluation-of-metformin-hydrochloride-rectal-dosage-forms-for-treatment-of-patients-with-type-ii-diabetes
#5
Abdel-Azim Zaghloul, Ahmad Lila, Fathy Abd-Allah, Aly Nada
BACKGROUND: Metformin hydrochloride (MtHCL) is an oral antidiabetic drug and has many other therapeutic benefits. It has poor bioavailability, narrow absorption window and extensive liver metabolism. Moreover, children and elders face difficulty to swallow the commercial oral tablets. OBJECTIVES: Preparation, in vitro/in vivo evaluation of MtHCL suppositories for rectal administration to solve some of these problems. METHODS: Suppository fatty bases (Witepsol®, Suppocire® and Massa®; different grades) and PEG bases 1000, 4000 and 6000 (different ratios), were used to prepare rectal suppository formulations each containing 500 mg drug...
January 16, 2017: Journal of Drug Targeting
https://www.readbyqxmd.com/read/28063680/gastric-tube-esophagoplasty-for-pediatric-esophageal-replacement
#6
Mahmoud M A Elfiky, Gamal El Tagy, Wissam Mohamed, Osama Abdel Azim, Mohamed A Elfiky
BACKGROUND: Esophageal replacement in children is indicated in cases of esophageal atresia with or without fistula, in case of long gap esophageal atresia or failed primary repair. Intractable post corrosive esophageal stricture is considered also a major indication for replacement. METHODS: This is a cohort retrospective study of esophageal replacement cases by gastric tube carried out at the pediatric surgery department at Cairo University between 2011 and 2015...
December 24, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28012528/the-effect-of-iv-dexamethasone-versus-local-anesthetic-infiltration-technique-in-postoperative-nausea-and-vomiting-after-tonsillectomy-in-children-a-randomized-double-blind-clinical-trial
#7
Zoher Naja, Saleh Kanawati, Rania Al Khatib, Fouad Ziade, Zeina Z Naja, Ahmad Salah Naja, Mariam Rajab
BACKGROUND: Local anesthetic infiltration and corticosteroids had shown effectiveness in reducing post tonsillectomy nausea, vomiting and pain. OBJECTIVES: To compare the effect of intravenous dexamethasone versus pre-incision infiltration of local anesthesia in pediatric tonsillectomy on postoperative nausea and vomiting (PONV). The secondary objective was postoperative pain. METHODS: A randomized double-blind clinical trial was conducted at a tertiary care teaching hospital...
January 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27943390/polyhydramnios-in-isolated-oral-cleft-pregnancies-incidence-and-outcome-in-a-retrospective-study
#8
Anne L Depla, Corstiaan C Breugem, Chantal M A M van der Horst, Roel de Heus, Marie-José H van den Boogaard, Saskia M Maas, Eva Pajkrt, Mireille N Bekker
OBJECTIVES: Polyhydramnios is suggested to be associated with oral clefts (OCs) due to swallowing problems. This study assessed incidence and outcome of idiopathic polyhydramnios in isolated OC pregnancies. METHODS: This was a retrospective cohort study of prenatally diagnosed OC. The incidence of idiopathic polyhydramnios in isolated OC pregnancies was determined. Pregnancy outcome, neonatal and paediatric follow-up were compared between cases with polyhydramnios and those with normal amniotic fluid...
December 11, 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27940673/can-a-flavored-spray-pill-glide-help-children-swallow-their-medicines-a-pilot-study
#9
Mamta Jagani, Hélène Legay, Sejal R Ranmal, Julie Bertrand, Kuan Ooi, Catherine Tuleu
Pediatric pharmacists are constantly faced with the challenges of supporting children and caregivers for whom the difficulties of swallowing medicines can be a daily struggle. Most medicines are only available as tablets and capsules, and where liquid alternatives exist, these products often have issues with palatability and high costs. The objective of this study was to evaluate whether the swallowing spray, Pill Glide, could help children in taking their solid and liquid medicines. This open label pilot study compared the spray with a behavioral approach alone, the current standard of care at the pediatric hospital...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27940507/titanium-dioxide-in-toothpaste-causing-yellow-nail-syndrome
#10
Ting-Yuan Hsu, Chun-Chen Lin, Ming-Dar Lee, Brian Pin-Hsuan Chang, Jeng-Daw Tsai
Yellow nail syndrome (YNS) is an uncommon disorder, the classic triad of which consists of yellow nails, lymphedema, and respiratory symptoms. Few pediatric cases have been reported. We report a 9-year-old girl with yellowish nail discoloration for 1 year accompanied by respiratory symptoms, including chronic cough, recurrent pneumonia, bronchiectasis, and chronic sinusitis. The patient was diagnosed with YNS. Knowing that a relationship between YNS and titanium has been reported, we collected her nail clippings and detected titanium in them by energy dispersive radiograph fluorescence...
January 2017: Pediatrics
https://www.readbyqxmd.com/read/27925397/both-pharyngeal-and-esophageal-phases-of-swallowing-are-associated-with-recurrent-pneumonia-in-pediatric-patients
#11
Selen Serel Arslan, Numan Demir, Aynur Ayşe Karaduman
INTRODUCTION: One of the underlying causes of recurrent pneumonia in children is swallowing dysfunction, with aspiration syndrome. Swallowing dysfunction should be considered not only a problem of the oropharyngeal phase but also a problem of the esophageal phase. OBJECTIVES: This study aimed to determine the relationship between findings from a swallowing study and a history of recurrent pneumonia in pediatric patients. METHODS: A videofluroscopic swallowing study of 274 pediatric patients who had swallowing dysfunction was conducted...
December 7, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27921260/development-of-oral-flexible-tablet-oft-formulation-for-pediatric-and-geriatric-patients-a-novel-age-appropriate-formulation-platform
#12
Prabagaran Chandrasekaran, Ruckmani Kandasamy
Development of palatable formulations for pediatric and geriatric patients involves various challenges. However, an innovative development with beneficial characteristics of marketed formulations in a single formulation platform was attempted. The goal of this research was to develop solid oral flexible tablets (OFTs) as a platform for pediatrics and geriatrics as oral delivery is the most convenient and widely used mode of drug administration. For this purpose, a flexible tablet formulation using cetirizine hydrochloride as model stability labile class 1 and 3 drug as per the Biopharmaceutical Classification System was developed...
December 5, 2016: AAPS PharmSciTech
https://www.readbyqxmd.com/read/27836445/-masticatory-system-and-maxillofacial-prosthesis-from-pathology-to-function-recovering
#13
S Vo Quang, J Dichamp
Maxillofacial prosthesis (MFP) can be defined as the art and science of esthetic and functional reconstruction of the facial bones, art because it uses hand-crafted and empirical rules, science because of its technical rigorism and its integration in medicine. MFP aims to multidisciplinary rehabilitate patients presenting with cutaneous and underlying structures defects, It also allows for functional speech and swallowing rehabilitation related to temporo-mandibular joint disorders. Whatever the origin, (traumatic, infectious ortumoral), surgical treatment of these TMJ disorders is usually not indicated in first-line...
December 2016: Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale
https://www.readbyqxmd.com/read/27808413/a-new-solution-for-neonatal-bilateral-vocal-cord-paralysis-endoscopic-arytenoid-abduction-lateropexy
#14
Shahram Madani, Ádám Bach, Vera Matievics, Eszter Erdélyi, Balázs Sztanó, Ilona Szegesdi, Paul F Castellanos, László Rovó
OBJECTIVES/HYPOTHESIS: Bilateral vocal cord paralysis in early childhood is a life-threatening condition, which often requires immediate intervention. One of the treatment options is a quick, reversible simple suture vocal cord lateralizing technique, whereby the arytenoid cartilage is directly lateralized to the normal abducted position. Considering pediatric laryngeal anatomy, a small endolaryngeal thread guide instrument was designed for precise suture insertion. STUDY DESIGN: New instrument validation...
November 3, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27799750/averting-the-foul-taste-of-pediatric-medicines-improves-adherence-and-can-be-lifesaving-pheburane-%C3%A2-sodium-phenylbutyrate
#15
REVIEW
Gideon Koren, Michael J Rieder, Yona Amitai
BACKGROUND: Children's aversions to poor and mostly bitter tastes and their inability to swallow tablets and capsules are major challenges in pediatric medicine. Sodium phenylbutyrate (NaPB) is a lifesaving waste nitrogen, alternative to urea nitrogen, for individuals suffering from urea cycle disorders. A major issue in the use of NaPB is its highly foul taste, which often leads to children being unable to consume it, resulting in ineffective treatment, or alternatively, necessitating the application of the drug through a nasogastric tube or gastrostomy...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27743332/gastrointestinal-symptoms-predictors-of-health-related-quality-of-life-in-pediatric-patients-with-functional-gastrointestinal-disorders
#16
James W Varni, Robert J Shulman, Mariella M Self, Samuel Nurko, Miguel Saps, Shehzad A Saeed, Ashish S Patel, Chelsea Vaughan Dark, Cristiane B Bendo, John F Pohl
OBJECTIVES: To investigate the patient-reported multidimensional gastrointestinal symptoms predictors of generic health-related quality of life (HRQOL) in pediatric patients with functional gastrointestinal disorders (FGIDs). METHODS: The Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Scales and PedsQL™ 4.0 Generic Core Scales were completed in a 9-site study by 259 pediatric patients with functional constipation, functional abdominal pain (FAP), or irritable bowel syndrome (IBS)...
October 14, 2016: Quality of Life Research
https://www.readbyqxmd.com/read/27735932/pill-aversion-in-hiv-infected-pregnant-women-theory-to-practice
#17
R M Dorman, L M Yee, S H Sutton
In our perinatal HIV cohort, we have observed difficulty swallowing pills as a frequent and significant barrier to adherence to highly active antiretroviral therapy. We refer to this problem as pill aversion and define it as difficulty swallowing pills with no persistent medical or structural cause as well as the anxiety and physical symptoms associated with pill swallowing. By applying cognitive behavioral theory to behavioral patterns within our pregnant HIV-infected population, we seek to better understand the development and reinforcement of pill aversion behavior...
October 13, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27717297/dysphagia-progression-and-feeding-skills-following-pediatric-alkali-ingestion-injury-two-case-reports
#18
Anna M Follent, Anna F Rumbach, Elizabeth C Ward, Jeanne Marshall, Pamela Dodrill, Peter Lewindon
PURPOSE: There is limited information regarding the nature of dysphagia and feeding difficulties following alkali ingestion injury to inform multidisciplinary intervention. The aim was to describe the history and nature of chronic dysphagia and feeding difficulties in two children following severe alkali ingestion injury. METHODS: Medical records, primary caregiver report, and clinical assessment were used to compile detailed case histories and assess current dysphagia and feeding skills...
October 7, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27701706/pediatric-feeding-swallowing-yesterday-today-and-tomorrow
#19
Maureen A Lefton-Greif, Joan C Arvedson
Speech-language pathologists (SLPs) have played primary roles in the evaluation and management of children with feeding/swallowing disorders for more than five decades. Medical, surgical, and technological advances have improved the survival of young fragile infants and children, many of whom will present with feeding/swallowing problems. Regardless of their underlying etiologies, many of these children are at risk for aspiration-induced lung disease, undernutrition or malnutrition, developmental deficits, and stressful interactions with their caregivers...
November 2016: Seminars in Speech and Language
https://www.readbyqxmd.com/read/27683588/aspirating-and-nonaspirating-swallow-sounds-in-children-a-pilot-study
#20
Thuy Frakking, Anne Chang, Kerry O'Grady, Michael David, Kelly Weir
BACKGROUND: Cervical auscultation (CA) may be used to complement feeding/swallowing evaluations when assessing for aspiration. There are no published pediatric studies that compare the properties of sounds between aspirating and nonaspirating swallows. AIM: To establish acoustic and perceptual profiles of aspirating and nonaspirating swallow sounds and determine if a difference exists between these 2 swallowing types. METHODS: Aspiration sound clips were obtained from recordings using CA simultaneously undertaken with videofluoroscopic swallow study...
December 2016: Annals of Otology, Rhinology, and Laryngology
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