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https://www.readbyqxmd.com/read/27935170/ultrasound-of-oral-and-masticatory-muscles-why-every-neuromuscular-swallow-team-should-have-an-ultrasound-machine
#1
Lenie van den Engel-Hoek, Marloes Lagarde, Nens van Alfen
Patients with neuromuscular disorders often present with swallowing difficulties due to oral phase problems and pharyngeal residue after swallow. It is important to assess the underlying pathology and cause of the swallowing disturbance in this patient group, such as dystrophic changes in oral and masticatory muscles. This allows for more patient-tailored recommendations, for example optimal compensation strategies to maintain function for longer. Ultrasound can show structural changes caused by dystrophy or denervation of muscles, detect involuntary movements such as fasciculations, and provide dynamic video images of tongue motion during swallowing attempts...
December 9, 2016: Clinical Anatomy
https://www.readbyqxmd.com/read/27930930/numerical-simulation-of-interaction-between-organs-and-food-bolus-during-swallowing-and-aspiration
#2
Takahiro Kikuchi, Yukihiro Michiwaki, Seiichi Koshizuka, Tetsu Kamiya, Yoshio Toyama
The mechanism of swallowing is still not fully understood, because the process of swallowing is a rapid and complex interaction among several involved organs and the food bolus. In this work, with the aim of studying swallowing and aspiration processes noninvasively and systematically, a computer simulation method for analyzing the involved organs and water (considered as the food bolus) is proposed. The shape and motion of the organs involved in swallowing are modeled in the same way as in our previous study, by using the Hamiltonian moving particle simulation (MPS) method and forced displacements on the basis of motion in a healthy volunteer...
November 30, 2016: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/27925397/both-pharyngeal-and-esophageal-phases-of-swallowing-are-associated-with-recurrent-pneumonia-in-pediatric-patients
#3
Selen Serel Arslan, Numan Demir, Aynur Ayşe Karaduman
INTRODUCTION: One of the underlying causes of recurrent pneumonia in children is swallowing dysfunction, with aspiration syndrome. Swallowing dysfunction should be considered not only a problem of the oropharyngeal phase but also a problem of the esophageal phase. OBJECTIVES: This study aimed to determine the relationship between findings from a swallowing study and a history of recurrent pneumonia in pediatric patients. METHODS: A videofluroscopic swallowing study of 274 pediatric patients who had swallowing dysfunction was conducted...
December 7, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27921050/esophagus-related-symptoms-in-first-degree-relatives-of-patients-with-achalasia-is-screening-necessary
#4
Henning R Gockel, Moritz Lesse, Johannes Schumacher, Michaela Müller, Ines Gockel
BACKGROUND: Despite an increasing understanding of the pathophysiology of achalasia, the etiology of this esophageal motility disorder remains largely unknown. However, the occurrence of familial achalasia, its association with well-defined genetic syndromes, the candidate gene approach, and recent presentation of the first systematic genome-wide association study on achalasia suggest the involvement of genetic factors. METHODS: In this study we analyzed the frequency with which symptoms associated with esophageal function (swallowing difficulties, regurgitations, retrosternal cramps/pain, heartburn) occur in first-degree relatives of patients with achalasia to determine if screening is useful and justified against the background of early diagnosis in a genetically predisposed population...
October 2016: Visceral Medicine
https://www.readbyqxmd.com/read/27903192/stereotactic-radiosurgery-for-idiopathic-glossopharyngeal-neuralgia-an-international-multicenter-study
#5
Hideyuki Kano, Dusan Urgosik, Roman Liscak, Bruce E Pollock, Or Cohen-Inbar, Jason P Sheehan, Mayur Sharma, Danilo Silva, Gene H Barnett, David Mathieu, Nathaniel D Sisterson, L Dade Lunsford
OBJECTIVE The goal of this study was to evaluate the outcomes of Gamma Knife stereotactic radiosurgery (SRS) when used for patients with intractable idiopathic glossopharyngeal neuralgia. METHODS Six participating centers of the International Gamma Knife Research Foundation identified 22 patients who underwent SRS for intractable glossopharyngeal neuralgia between 1998 and 2015. The median patient age was 60 years (range 34-83 years). The median duration of symptoms before SRS was 46 months (range 1-240 months)...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27901263/negative-effects-of-submandibular-botulinum-neurotoxin-a-injections-on-oral-motor-function-in-children-with-drooling-due-to-central-nervous-system-disorders
#6
Karen van Hulst, Carlyn V Kouwenberg, Pieter H Jongerius, Ton Feuth, Franciscus J A van den Hoogen, Alexander C H Geurts, Corrie E Erasmus
AIM: The aims of this study were: (1) to determine the incidence and nature of adverse effects on oral motor function after first injections of botulinum neurotoxin A (BoNT-A) in submandibular glands for excessive drooling in children with central nervous system disorders; and (2) to identify independent predictors of these adverse effects. METHOD: A cohort study involved 209 children (123 males, 86 females, aged 4-27y, median 8y 4mo), who received submandibular BoNT-A injections for drooling...
November 30, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27884168/ataxia-telangiectasia-a-review
#7
REVIEW
Cynthia Rothblum-Oviatt, Jennifer Wright, Maureen A Lefton-Greif, Sharon A McGrath-Morrow, Thomas O Crawford, Howard M Lederman
DEFINITION OF THE DISEASE: Ataxia telangiectasia (A-T) is an autosomal recessive disorder primarily characterized by cerebellar degeneration, telangiectasia, immunodeficiency, cancer susceptibility and radiation sensitivity. A-T is often referred to as a genome instability or DNA damage response syndrome. EPIDEMIOLOGY: The world-wide prevalence of A-T is estimated to be between 1 in 40,000 and 1 in 100,000 live births. CLINICAL DESCRIPTION: A-T is a complex disorder with substantial variability in the severity of features between affected individuals, and at different ages...
November 25, 2016: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/27873090/evaluating-the-psychometric-properties-of-the-eating-assessment-tool-eat-10-using-rasch-analysis
#8
R Cordier, A Joosten, P Clavé, A Schindler, M Bülow, N Demir, S Serel Arslan, R Speyer
Early and reliable screening for oropharyngeal dysphagia (OD) symptoms in at-risk populations is important and a crucial first stage in effective OD management. The Eating Assessment Tool (EAT-10) is a commonly utilized screening and outcome measure. To date, studies using classic test theory methodologies report good psychometric properties, but the EAT-10 has not been evaluated using item response theory (e.g., Rasch analysis). The aim of this multisite study was to evaluate the internal consistency and structural validity and conduct a preliminary investigation of the cross-cultural validity of the EAT-10; floor and ceiling effects were also checked...
November 21, 2016: Dysphagia
https://www.readbyqxmd.com/read/27859412/oesophageal-lichen-planus-the-efficacy-of-topical-steroid-based-therapies
#9
A Podboy, D Sunjaya, T C Smyrk, J A Murray, M Binder, D A Katzka, J A Alexander, M Halland
BACKGROUND: Oesophageal lichen planus is an idiopathic inflammatory disorder characterized by significant oesophageal stricturing. Oesophageal lichen planus is a rare, difficult to diagnose, and likely an under recognized disease. As a result, there is no standardized approach to therapy and treatment strategies vary. AIM: To examine the utility of topical steroid therapy (fluticasone or budesonide) in the management of oesophageal lichen planus. METHODS: A retrospective chart review was conducted of patients diagnosed with oesophageal lichen planus who underwent baseline and follow up endoscopy pre and post topical steroid therapy between 1995 and 2016 at Mayo Clinic, Rochester MN...
January 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27853394/long-term-impact-after-fulminant-guillain-barr%C3%A3-syndrome-case-report-and-literature-review
#10
Alain Rougé, Jérémie Lemarié, Sébastien Gibot, Pierre Edouard Bollaert
A 47-year-old man was admitted to the intensive care unit a few hours after presenting to emergency department with acute diplopia and dysphonia. Swallowing disorders and respiratory muscular weakness quickly required invasive ventilation. On day 3, the patient was in a "brain-death"-like state with deep coma and absent brainstem reflexes. Electroencephalogram ruled out brain death diagnosis as a paradoxical sleep trace was recorded. Cerebrospinal fluid analysis, electrophysiologic studies, and a recent history of diarrhea led to the diagnosis of Campylobacter jejuni-related fulminant Guillain-Barré syndrome (GBS) mimicking brain death...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27843470/childhood-neurogenic-stuttering-due-to-bilateral-congenital-abnormality-in-globus-pallidus-a-case-report-and-review-of-the-literature
#11
Mohammad Javad Saeedi, Ebrahim Esfandiary, Mostafa Almasi Dooghaee
Objective The basal ganglia are a group of structures that act as a cohesive functional unit. They are situated at the base of the forebrain and are strongly connected with the cerebral cortex and thalamus. Some speech disorders such as stuttering can resulted from disturbances in the circuits between the basal ganglia and the language motor area of the cerebral cortex. Stuttering consists of blocks, repetitive, prolongation or cessation of speech. We present a 7.5 -year-old male child with bilateral basal ganglia lesion in globus pallidus with unclear reason...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/27836445/-masticatory-system-and-maxillofacial-prosthesis-from-pathology-to-function-recovering
#12
S Vo Quang, J Dichamp
Maxillofacial prosthesis (MFP) can be defined as the art and science of esthetic and functional reconstruction of the facial bones, art because it uses hand-crafted and empirical rules, science because of its technical rigorism and its integration in medicine. MFP aims to multidisciplinary rehabilitate patients presenting with cutaneous and underlying structures defects, It also allows for functional speech and swallowing rehabilitation related to temporo-mandibular joint disorders. Whatever the origin, (traumatic, infectious ortumoral), surgical treatment of these TMJ disorders is usually not indicated in first-line...
December 2016: Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale
https://www.readbyqxmd.com/read/27831909/blended-foods-for-tube-fed-children-a-safe-and-realistic-option-a-rapid-review-of-the-evidence
#13
REVIEW
Jane Coad, Alex Toft, Susie Lapwood, Joseph Manning, Mark Hunter, Huw Jenkins, Clare Sadlier, Julie Hammonds, Ailsa Kennedy, Simon Murch, David Widdas
With the growing number of children and young people with complex care needs or life-limiting conditions, alternative routes for nutrition have been established (such as gastrostomy feeding). The conditions of children and young people who require such feeding are diverse but could relate to problems with swallowing (dysphagia), digestive disorders or neurological/muscular disorders. However, the use of a blended diet as an alternative to prescribed formula feeds for children fed via a gastrostomy is a contentious issue for clinicians and researchers...
October 18, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/27818585/update-on-the-endoscopic-treatments-for-achalasia
#14
REVIEW
Dushant S Uppal, Andrew Y Wang
Achalasia is the most common primary motility disorder of the esophagus and presents as dysphagia to solids and liquids. It is characterized by impaired deglutitive relaxation of the lower esophageal sphincter. High-resolution manometry allows for definitive diagnosis and classification of achalasia, with type II being the most responsive to therapy. Since no cure for achalasia exists, early diagnosis and treatment of the disease is critical to prevent end-stage disease. The central tenant of diagnosis is to first rule out mechanical obstruction due to stricture or malignancy, which is often accomplished by endoscopic and fluoroscopic examination...
October 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27808413/a-new-solution-for-neonatal-bilateral-vocal-cord-paralysis-endoscopic-arytenoid-abduction-lateropexy
#15
Shahram Madani, Ádám Bach, Vera Matievics, Eszter Erdélyi, Balázs Sztanó, Ilona Szegesdi, Paul F Castellanos, László Rovó
OBJECTIVES/HYPOTHESIS: Bilateral vocal cord paralysis in early childhood is a life-threatening condition, which often requires immediate intervention. One of the treatment options is a quick, reversible simple suture vocal cord lateralizing technique, whereby the arytenoid cartilage is directly lateralized to the normal abducted position. Considering pediatric laryngeal anatomy, a small endolaryngeal thread guide instrument was designed for precise suture insertion. STUDY DESIGN: New instrument validation...
November 3, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27808029/-paraneoplastic-myasthenia-gravis-and-polymyositis-secondary-to-a-thymoma-in-a-young-woman
#16
Shabnam Ezzatian-Ahar, Emil Greve Pedersen, Henrik Daa Schrøder, Hans Christian Horn, David Gaist
We present the case of a 33-year-old woman who within weeks developed severe swallowing difficulties and weakness in her limbs to an extent requiring hospitalization. Workup confirmed clinically suspected diagnoses of polymyositis and autoimmune myasthenia. A suspicion of malignant thymoma based on chest computed tomography was histologically verified. Patient treatment and response are presented. The case emphasizes the importance of recognizing that thymomas, in rare instances, may present with a combination of neuromuscular disorders in the same patient...
October 24, 2016: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/27799750/averting-the-foul-taste-of-pediatric-medicines-improves-adherence-and-can-be-lifesaving-pheburane-%C3%A2-sodium-phenylbutyrate
#17
REVIEW
Gideon Koren, Michael J Rieder, Yona Amitai
BACKGROUND: Children's aversions to poor and mostly bitter tastes and their inability to swallow tablets and capsules are major challenges in pediatric medicine. Sodium phenylbutyrate (NaPB) is a lifesaving waste nitrogen, alternative to urea nitrogen, for individuals suffering from urea cycle disorders. A major issue in the use of NaPB is its highly foul taste, which often leads to children being unable to consume it, resulting in ineffective treatment, or alternatively, necessitating the application of the drug through a nasogastric tube or gastrostomy...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27788643/people-with-dementia-can-learn-compensatory-swallowing-behaviours-for-safety
#18
(no author information available yet)
People with swallowing disorders and memory deficits associated with dementia often find learning self-feeding strategies difficult.
October 28, 2016: Nursing Older People
https://www.readbyqxmd.com/read/27785002/european-society-for-swallowing-disorders-european-union-geriatric-medicine-society-white-paper-oropharyngeal-dysphagia-as-a-geriatric-syndrome
#19
REVIEW
Laura Wj Baijens, Pere Clavé, Patrick Cras, Olle Ekberg, Alexandre Forster, Gerald F Kolb, Jean-Claude Leners, Stefano Masiero, Jesús Mateos-Nozal, Omar Ortega, David G Smithard, Renée Speyer, Margaret Walshe
This position document has been developed by the Dysphagia Working Group, a committee of members from the European Society for Swallowing Disorders and the European Union Geriatric Medicine Society, and invited experts. It consists of 12 sections that cover all aspects of clinical management of oropharyngeal dysphagia (OD) related to geriatric medicine and discusses prevalence, quality of life, and legal and ethical issues, as well as health economics and social burden. OD constitutes impaired or uncomfortable transit of food or liquids from the oral cavity to the esophagus, and it is included in the World Health Organization's classification of diseases...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27782297/botulinum-toxin-type-a-versus-botulinum-toxin-type-b-for-cervical-dystonia
#20
REVIEW
Gonçalo S Duarte, Mafalda Castelão, Filipe B Rodrigues, Raquel E Marques, Joaquim Ferreira, Cristina Sampaio, Austen P Moore, João Costa
BACKGROUND: This is an update of a Cochrane review first published in 2003. Cervical dystonia is the most common form of focal dystonia and is a disabling disorder characterised by painful involuntary head posturing. There are two available formulations of botulinum toxin, with botulinum toxin type A (BtA) usually considered the first line therapy for this condition. Botulinum toxin type B (BtB) is an alternative option, with no compelling theoretical reason why it might not be as- or even more effective - than BtA...
October 26, 2016: Cochrane Database of Systematic Reviews
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