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Fetal cerebral artery

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https://www.readbyqxmd.com/read/28541503/reduced-efficacy-of-the-pipeline-embolization-device-in-the-treatment-of-posterior-communicating-region-aneurysms-with-fetal-posterior-cerebral-artery-configuration
#1
Anil K Roy, Brian M Howard, Diogo C Haussen, Joshua W Osbun, Sameer H Halani, Susana L Skukalek, Frank Tong, Raul G Nogueira, Jacques E Dion, Charles M Cawley, Jonathan A Grossberg
BACKGROUND: Aneurysms at the origin of the posterior communicating artery (PcommA) have been demonstrated to be effectively treated with the pipeline embolization device (PED). Much less is known about the efficacy of the PED for aneurysms associated with a fetal posterior cerebral artery (fPCA) variant. OBJECTIVE: To study PED treatment efficacy of PcommA aneurysms, including fPCA aneurysms. METHODS: A prospectively maintained university database of aneurysm patients treated with the PED was retrospectively reviewed...
May 25, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28467985/effects-of-antenatal-melatonin-treatment-on-the-cerebral-vasculature-in-an-ovine-model-of-fetal-growth-restriction
#2
Margie Castillo-Melendez, Tamara Yawno, Amy Sutherland, Graham Jenkin, Euan M Wallace, Suzanne L Miller
Chronic moderate hypoxia, such as occurs in fetal growth restriction (FGR) during gestation, compromises the blood-brain barrier (BBB) and results in structural abnormalities of the cerebral vasculature. We have previously determined the neuroprotective and antioxidant effects of maternal administration of melatonin (MLT) on growth-restricted newborn lambs. The potential of maternal MLT therapy for the treatment of cerebrovascular dysfunction-associated developmental hypoxia has also been demonstrated in newborn lambs...
May 4, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28436166/perinatal-loss-at-term-the-role-of-uteroplacental-and-fetal-doppler-assessment
#3
Caitriona Monaghan, Julia Binder, Baskaran Thilaganathan, José Morales-Roselló, Asma Khalil
OBJECTIVE: To examine the association of uterine artery (UtA) Doppler indices and cerebroplacental ratio (CPR) on perinatal outcome at term. METHODS: This retrospective cohort study conducted in a single tertiary referral centre included all singleton pregnancies undergoing ultrasound assessment in the third trimester, which subsequently delivered at term. Fetal biometry and Dopplers including the umbilical artery (UA), middle cerebral artery (MCA) and uterine artery were recorded...
April 24, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28413694/first-neonatal-demise-with-travel-associated-zika-virus-infection-in-the-united-states-of-america
#4
Nikolaos Zacharias, Janice Whitty, Sarah Noblin, Sophia Tsakiri, Jose Garcia, Michael Covinsky, Meenakshi Bhattacharjee, David Saulino, Nina Tatevian, Sean Blackwell
Zika virus is increasingly recognized as a fetal pathogen worldwide. We describe the first case of neonatal demise with travel-associated Zika virus infection in the United States of America, including a novel prenatal ultrasound finding. A young Latina presented to our health care system in Southeast Texas for prenatal care at 23 weeks of gestation. Fetal Dandy-Walker malformation, asymmetric cerebral ventriculomegaly, single umbilical artery, hypoechoic fetal knee, dorsal foot edema, and mild polyhydramnios were noted upon initial screening prenatal sonography at 26 weeks...
April 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28409154/suspected-fetal-growth-restriction-at-37-weeks-a-comparison-of-doppler-and-placental-pathology
#5
William M Curtin, Karmaine A Millington, Tochi O Ibekwe, Serdar H Ural
Objective. Our objective was determining if abnormal Doppler evaluation had a higher prevalence of placental pathology compared to normal Doppler in suspected fetal growth restriction (FGR) of cases delivered at 37 weeks. Study Design. This retrospective cohort study of suspected FGR singletons with antenatal Doppler evaluation delivered at 37 weeks had a primary outcome of the prevalence of placental pathology related to FGR. Significance was defined as p ≤ 0.05. Results. Of 100 pregnancies 46 and 54 were in the abnormal and normal Doppler cohorts, respectively...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28403927/relevance-of-routine-doppler-sampling-at-the-two-umbilical-arteries-in-the-follow-up-of-dichorionic-twin-pregnancies-with-intrauterine-growth-restricted-fetuses
#6
A J Vivanti, E Lecarpentier, A-G Cordier, F Proulx, V Tsatsaris, A Benachi
OBJECTIVE: The aim of this study is to assess if the presence of bilateral absent or reverse end-diastolic velocity (AREDV) indicates a poorer prognosis than unilateral AREDV in dichorionic-diamniotic twin pregnancies complicated by intrauterine growth restriction. METHODS: A prospective observational study of 36 dichorionic-diamniotic twin pregnancies complicated by intrauterine growth restriction. One hundred and fifty seven ultrasound (US) examinations were performed...
March 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28396818/comment-on-failure-of-the-pipeline-embolization-device-in-posterior-communicating-artery-aneurysms-associated-with-a-fetal-posterior-cerebral-artery
#7
COMMENT
Visish M Srinivasan, Peter Kan
No abstract text is available yet for this article.
2017: Case Reports in Vascular Medicine
https://www.readbyqxmd.com/read/28387144/antenatal-dexamethasone-before-asphyxia-promotes-cystic-neural-injury-in-preterm-fetal-sheep-by-inducing-hyperglycemia
#8
Christopher A Lear, Joanne O Davidson, Georgia R Mackay, Paul P Drury, Robert Galinsky, Josine S Quaedackers, Alistair J Gunn, Laura Bennet
Antenatal glucocorticoid therapy significantly improves the short-term systemic outcomes of prematurely born infants, but there is limited information available on their impact on neurodevelopmental outcomes in at-risk preterm babies exposed to perinatal asphyxia. Preterm fetal sheep (0.7 of gestation) were exposed to a maternal injection of 12 mg dexamethasone or saline followed 4 h later by asphyxia induced by 25 min of complete umbilical cord occlusion. In a subsequent study, fetuses received titrated glucose infusions followed 4 h later by asphyxia to examine the hypothesis that hyperglycemia mediated the effects of dexamethasone...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28369985/nongalenic-pial-arteriovenous-fistula-prenatal-diagnosis
#9
Cristina Martínez-Payo, Javier Sancho Saúco, Maria Miralles, Tirso Pérez Medina
Pial arteriovenous (AV) fistulae have rarely been diagnosed in utero. They are characterized by one or more pial arteries flowing directly into a cortical vein without any shunt or interposed capillary bed. In the fetus and the newborn up to 2 years of age, the most common clinical manifestation is heart failure resulting from fistula overload. Later on, hydrocephalus, focal neurologic deficits, headaches, seizures, and cerebral hemorrhage are the most common manifestations. We present a case of nongalenic pial AV fistula diagnosed in the 25th week of pregnancy, which resulted in intrauterine fetal death due to congestive heart failure...
April 3, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28355685/-clinical-outcome-and-placenta-characteristics-of-spontaneous-twin-anemia-polycythemia-sequence
#10
X J Wang, L Y Li, Y Wei, Y Y Zhao, P B Yuan
Objective: To investigate the clinical outcome and placental characteristics of spontaneous twin anemia-polycythemia sequence (sTAPS). Methods: Twelve cases with sTAPS delivered in Peking University Third Hospital from May 2013 to August 2016. The data of ultrasound characteristics, gestational age at delivery, and 1 minute Apgar score were analyzed, retrospectively. Placental superficial vascular anastomoses, placental territory discordance and the ratio of umbilical cords insertion distance to the longest placental diameter were also analyzed...
March 25, 2017: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/28345186/use-of-the-fetal-myocardial-performance-index-in-assessment-and-management-of-the-small-for-gestational-age-fetus-a-cohort-and-nested-case-control-study
#11
Amanda Henry, Jennifer Alphonse, Dominique Tynan, Alec W Welsh
OBJECTIVES: To assess the clinical utility of the fetal Myocardial Performance Index (MPI) in assessment and management of the fetus referred to Fetal Medicine services for Small for Gestational Age/Intrauterine Growth Restriction (SGA/IUGR). METHODS: Prospective cohort study in metropolitan Australia. Consenting patients referred at 24-38 weeks' gestation for suspected singleton SGA/IUGR (estimated fetal weight [EFW] <10(th) centile for gestation and/or abnormal umbilical artery [UA] Doppler) had MPI performed in addition to routine measures, and were followed through to birth...
March 27, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28295352/should-optimal-timing-between-two-intrauterine-transfusions-be-based-on-estimated-daily-decrease-of-hemoglobin-or-on-measurement-of-fetal-middle-cerebral-artery-peak-systolic-velocity
#12
Louise Ghesquière, Véronique Houfflin-Debarge, Hélène Behal, Capucine Coulon, Damien Subtil, Pascal Vaast, Charles Garabedian
BACKGROUND: To best predict the recurrence of fetal anemia after intrauterine transfusion (IUT), the measurement of middle cerebral artery peak systolic velocity (PSV) and the estimation of hemoglobin (Hb) daily decrease are compared. STUDY DESIGN AND METHODS: A retrospective study including 38 patients who had at least two IUTs in a context of red blood cell alloimmunization was conducted. PSV values before first, second, and third IUTs were collected and expected Hb level was calculated according to various Hb daily decrease formulas as proposed in the literature...
April 2017: Transfusion
https://www.readbyqxmd.com/read/28294442/prediction-of-adverse-perinatal-outcome-by-cerebroplacental-ratio-adjusted-for-estimated-fetal-weight
#13
Angelo Sirico, Anke Diemert, Peter Glosemeyer, Kurt Hecher
OBJECTIVES: The aim of our study was to evaluate the relationship between the cerebroplacental ratio (CPR) and estimated fetal weight (EFW). Furthermore, we evaluated the role of CPR in the prediction of adverse perinatal outcome and whether CPR measurements adjusted for EFW improve its predictive value. METHODS: This is a retrospective cohort study including pregnancies, where Doppler investigations of umbilical artery (UA) and middle cerebral artery (MCA) were performed after 30 weeks...
March 12, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28279117/progression-of-doppler-changes-in-early-onset-small-for-gestational-age-fetuses-how-frequent-are-the-different-progression-sequences
#14
José Morales-Roselló, Asma Khalil, Victoria Fornés-Ferrer, José Alberola-Rubio, David Hervas-Marín, Núria Peralta Llorens, Alfredo Perales-Marín
OBJECTIVE: To evaluate the progression of Doppler abnormalities in early-onset fetal smallness (SGA). METHODS: A total of 948 Doppler examinations of the umbilical artery (UA), middle cerebral artery (MCA) and ductus venosus (DV), belonging to 405 early-onset SGA fetuses, were studied, evaluating the sequences of Doppler progression, the interval examination-labor at which Doppler became abnormal and the cumulative sum of Doppler anomalies in relation with labor proximity...
March 27, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28278506/accuracy-of-middle-cerebral-artery-doppler-assessment-between-34-and-37-weeks-in-fetuses-with-red-cell-alloimmunization
#15
Emeline Maisonneuve, Aude Jayot, Stéphanie Friszer, Vanina Castaigne, Evelyne Cynober, Françoise Pernot, Agnès Mailloux, Jean-Marie Jouannic, Anne Cortey, Bruno Carbonne
BACKGROUND: The Doppler measurement of middle cerebral artery peak systolic velocity (MCA-PSV) is considered the gold standard for the noninvasive detection of moderate to severe anemia. However, the accuracy of this test has not been evaluated so far, specifically beyond 34 weeks. OBJECTIVES: To assess the accuracy of MCA-PSV to detect moderate to severe fetal anemia and to identify risk factors associated with false-positive and false-negative MCA-PSV values after 34 weeks...
March 10, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28277907/the-effect-of-maternal-hyperoxygenation-on-fetal-circulatory-system-in-normal-growth-and-iugr-fetuses-what-we-can-learn-from-this-impact
#16
Nizar Khatib, Israel Thaler, Ron Beloosesky, Hanin Dabaja, Nadir Ganem, Philippe Abecassis, Yuval Ginsberg, Zeev Weiner
PURPOSE: The objectives of study were to assess and compare the effects of maternal hyperoxygenation on fetal circulation, in fetuses with intrauterine growth retardation and normal fetal growth. METHODS: Twelve singleton pregnant women with normal fetal growth and 12 singleton pregnant women with intrauterine growth restriction were recruited. Mean gestational age of 35.2 ± 3.5 and 34.7 ± 3.9 weeks, respectively. Doppler blood flow velocity waveforms were obtained from the middle cerebral artery, umbilical, main and proximal right pulmonary arteries...
March 21, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28258054/thrombophilia-risk-is-not-increased-in-children-after-perinatal-stroke
#17
Colleen Curtis, Aleksandra Mineyko, Patricia Massicotte, Michael Leaker, Xiu Yan Jiang, Amalia Floer, Adam Kirton
Perinatal stroke causes cerebral palsy and lifelong disability. Specific diseases are definable but mechanisms are poorly understood. Evidence suggests possible associations between arterial perinatal stroke and prothrombotic disorders but population-based, controlled, disease-specific studies are limited. Understanding thrombophilia in perinatal stroke informs pathogenesis models and clinical management. We conducted a population-based, prospective, case-control study to determine the association of specific perinatal stroke diseases with known thrombophilias...
March 3, 2017: Blood
https://www.readbyqxmd.com/read/28203181/bilateral-superior-cerebellar-artery-embolic-occlusion-with-a-fetal-type-posterior-cerebral-artery-providing-collateral-circulation
#18
Taylor J Bergman, Rachael C Saporito, Thomas Hope
Bilateral infarction of the superior cerebellar arteries with sparing of the rest of the posterior circulation, particularly the posterior cerebral arteries, is an uncommon finding in neurological practice. Most commonly, the deficits of the superior cerebellar arteries and posterior cerebral arteries occur together due to the close proximity of their origins at the top of the basilar artery. A patient was transferred to the neurological intensive care unit with a history of recent-onset falls from standing, profound hypertension, dizziness, and headaches...
September 2016: Case Reports in Neurology
https://www.readbyqxmd.com/read/28180200/acoustic-radiation-force-impulse-elastosonography-of-placenta-in-maternal-red-blood-cell-alloimmunization-a-preliminary-and-descriptive-study
#19
Orkun Cetin, Erbil Karaman, Harun Arslan, Ibrahim Akbudak, Recep Yıldızhan, Ali Kolusarı
AIMS: Maternal red blood cell alloimmunization is an important cause of fetal morbidity and mortality in the perinatal period, despite well-organized prophylaxis programs. The objective of the study was to evaluate placental elasticity by using Acoustic Radiation Force Impulse (ARFI) in Rhesus (Rh) alloimmunized pregnant women with hydropic and nonhydropic fetuses and to compare those with healthy pregnant women. MATERIAL AND METHODS: This case-control and descriptive study comprised twenty-eight healthy pregnant women, 14 Rh alloimmunized pregnant women with nonhydropic fetuses, and 16 Rh alloimmunized pregnant women with hydropic fetuses in the third trimester of pregnancy...
January 31, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28114884/everrest-prospective-study-a-6-year-prospective-study-to-define-the-clinical-and-biological-characteristics-of-pregnancies-affected-by-severe-early-onset-fetal-growth-restriction
#20
Rebecca Spencer, Gareth Ambler, Jana Brodszki, Anke Diemert, Francesc Figueras, Eduard Gratacós, Stefan R Hansson, Kurt Hecher, Angela Huertas-Ceballos, Neil Marlow, Karel Marsál, Eva Morsing, Donald Peebles, Carlo Rossi, Neil J Sebire, John F Timms, Anna L David
BACKGROUND: Fetal growth restriction (FGR) is a serious obstetric condition for which there is currently no treatment. The EVERREST Prospective Study has been designed to characterise the natural history of pregnancies affected by severe early onset FGR and establish a well phenotyped bio-bank. The findings will provide up-to-date information for clinicians and patients and inform the design and conduct of the EVERREST Clinical Trial: a phase I/IIa trial to assess the safety and efficacy of maternal vascular endothelial growth factor (VEGF) gene therapy in severe early onset FGR...
January 23, 2017: BMC Pregnancy and Childbirth
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