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https://www.readbyqxmd.com/read/29891425/wilderness-mass-casualty-incident-mci-rescue-chain-after-avalanche-at-everest-base-camp-ebc-in-2015
#1
Ken Zafren, Anne Brants, Katie Tabner, Andrew Nyberg, Matiram Pun, Buddha Basnyat, Monika Brodmann Maeder
The Nepal Earthquake of 2015 killed over 8000 people and injured over 20,000 in Nepal. Moments after the earthquake, an avalanche of falling ice came down from above Everest Base Camp (EBC). The air blast created by the avalanche flattened the middle part of EBC, killing 15 people and injuring at least 70. The casualties were initially triaged and treated at EBC and then evacuated by air to Kathmandu for definitive care. There were intermediate stops at the villages of Pheriche and Lukla during which the casualties were offloaded, retriaged, treated, and loaded again for further transport...
June 8, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/29887348/case-report-severe-frostbite-in-extreme-altitude-climbers-the-kathmandu-iloprost-experience
#2
Prativa Pandey, Ravi Vadlamudi, Rashila Pradhan, Kishore R Pandey, Alex Kumar, Peter Hackett
Severe frostbite occurs frequently at extreme altitude in the Himalayas, often resulting in amputations. Recent advances in treatment of frostbite injuries with either intravenous or intra-arterial tissue plasminogen activator, or with iloprost, have improved outcomes in frostbite injuries, but only if the patient has access to these within 24 to 48 h postinjury, and ideally even sooner. Frostbitten Himalayan climbers are seldom able to reach medical care in this time frame. We wished to see if delayed iloprost use (up to 72 h) would help reduce tissue loss in grade 3 to 4 frostbite...
June 7, 2018: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/29880002/life-satisfaction-among-elderly-patients-in-nepal-associations-with-nutritional-and-mental-well-being
#3
Saruna Ghimire, Binaya Kumar Baral, Isha Karmacharya, Karen Callahan, Shiva Raj Mishra
BACKGROUND: Nepal's demography is aging rapidly, yet few studies to date have examined how this has affected the health and well-being of the elderly, defined as those above 60 years in Nepal's Senior Citizen Act (2006). Our study, abbreviated NepEldQOLII, aims to assess perceived life satisfaction, and evaluate its relationship with nutritional health and mental well-being among the burgeoning Nepalese elderly population. METHODS: A cross-sectional survey among 289 Nepalese elderly, aged ≥60 years, attending an outpatient clinic of a hospital in Kathmandu, Nepal was conducted...
June 7, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29808233/prevalence-and-genotypic-diversity-of-entamoeba-species-in-inhabitants-in-kathmandu-nepal
#4
Meng Feng, Kishor Pandey, Tetsuo Yanagi, Ting Wang, Chaturong Putaporntip, Somchai Jongwutiwes, Xunjia Cheng, Jeevan B Sherchand, Basu Dev Pandey, Hiroshi Tachibana
In Nepal, gastrointestinal infections due to parasites including Entamoeba species are common. The main aim of this study was to identify species of Entamoeba using genotypic analysis. The prevalence of Entamoeba infections was examined by PCR in fecal samples from 143 inhabitants living close to wild rhesus macaques in Kathmandu, Nepal. The numbers of positive cases were one (0.7%) for E. histolytica, eight (5.6%) for E. dispar, seven (4.9%) for E. coli, and two (1.4%) for E. chattoni (E. polecki ST2). No infections with E...
May 28, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29764503/bacteriological-profile-of-neonatal-sepsis-and-antibiotic-susceptibility-pattern-of-isolates-admitted-at-kanti-children-s-hospital-kathmandu-nepal
#5
Nikita Singh Yadav, Saroj Sharma, Dhiraj Kumar Chaudhary, Prabhat Panthi, Pankaj Pokhrel, Anil Shrestha, Pappu Kumar Mandal
OBJECTIVE: Neonatal sepsis is a major cause of morbidity and mortality of newborns (< 1 month of age). Septicemia and drug resistance is a predominant issue for neonatal death in Nepal. This study is intended to find bacteriological profile of neonatal sepsis and antibiotic susceptibility pattern of the isolates from neonates at Kanti Children's Hospital, Kathmandu, Nepal. RESULTS: Out of 350 suspected cases of neonatal sepsis, 59 (16.9%) cases showed positive blood culture...
May 15, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29743786/awareness-of-occupational-hazards-and-associated-factors-among-automobile-repair-artisans-in-kathmandu-metropolitan-city-nepal
#6
Sujan B Marahatta, Sanju Gautam, Grish Paudel, Uday N Yadav
Background: An occupational hazard contributes to severe health problems among workers due to unhygienic conditions and lack of safety at the workplace. Economic growth and productivity can be well achieved by promoting health, safety, and improved quality workplace. Aims: To assess the knowledge of occupational hazards, use of Personal Protective Equipment (PPE) and the factors associated with awareness on occupational hazards among automobile repair artisans in Kathmandu, Nepal...
January 2018: Indian Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29731643/ugly-bugs-in-healthy-guts-carriage-of-multidrug-resistant-and-esbl-producing-commensal-enterobacteriaceae-in-the-intestine-of-healthy-nepalese-adults
#7
Anjila Maharjan, Anjeela Bhetwal, Shreena Shakya, Deepa Satyal, Shashikala Shah, Govardhan Joshi, Puspa Raj Khanal, Narayan Prasad Parajuli
Background: Fecal carriage of multidrug-resistant and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is one of the important risk factors for infection with antibiotic-resistant bacteria. In this report, we examined the prevalence of multidrug-resistant and ESBL-producing common enterobacterial strains colonizing the intestinal tract of apparently healthy adults in Kathmandu, Nepal. Methods: During a 6-month period (February-July 2016), a total of 510 stool specimens were obtained from apparently healthy students of Manmohan Memorial Institute of Health Sciences, Kathmandu, Nepal...
2018: Infection and Drug Resistance
https://www.readbyqxmd.com/read/29717297/comparison-of-stage-and-lymph-node-ratio-in-young-and-older-patients-with-colorectal-cancer-operated-in-a-tertiary-hospital-in-nepal
#8
Bikal Ghimire, Yogendra Prasad Singh, Goran Kurlberg, Yvonne Wettergren
BACKGROUND: Colorectal cancer is being diagnosed more frequently in the young and it presents in an advanced stage. In TNM staging, stage depends on tumor size and number of positive nodes, which depend on location of tumor as well as the extent of dissection.The lymph node ratio is regarded as a more reliable marker for prognosis. In this study, we compare epidemiology of colorectal cancer in the young (<40 years) and older patients as well as the LNR. METHODS: Patients with colorectal cancer operated at the Tribhuvan University Teaching Hospital, Kathmandu, Nepal for a period of 4 years (2012 - 2016) were included in the study...
March 13, 2018: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/29717291/evaluation-of-pain-following-the-use-of-scalpel-versus-diathermy-for-skin-incision-in-ear-nose-throat-and-head-and-neck-surgeries
#9
Diva Shrestha
BACKGROUND: Many studies have shown the benefits of diathermy over scalpel for making skin incisions in terms of post operative pain and post operative analgesics requirement. The objective of the study is to compare the pain following incision by scalpel and diathermy for skin in ENT surgery. METHODS: We conducted a prospective, randomized study and compared early post operative pain and analgesics requirement in patients undergoing ENT and Head and Neck surgery in Department of ENT at Kathmandu Medical College from September 2016 to August 2017...
March 13, 2018: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/29717286/quality-of-life-of-peri-and-postmenopausal-women-attending-outpatient-department-of-obstretics-and-gynecology-of-a-tertiary-care-hospital
#10
Sunita Koirala, Naresh Manandhar
BACKGROUND: Many women experience menopausal symptoms during menopausal transition and postmenopausal years. This natural phenomenon often results in various psychological, somatic and urinary symptoms which impair the overall quality of life of women. This study aimed to access the quality of life of women during perimenopausal and early postmenopausal years attending outpatient department of OBGYN at Kathmandu Medical College Teaching Hospital. METHODS: A descriptive cross-sectional study of 240 perimenopausal women of aged 45-60 years attending gynaecological outpatient clinic was carried out between 15th January to 13th April 2017...
March 13, 2018: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/29717284/antibiotic-susceptibility-pattern-of-gram-negative-isolates-of-lower-respiratory-tract-infection
#11
Rakshya Nepal, Basudha Shrestha, Deepak Man Joshi, Rajesh Dhoj Joshi, Sanjit Shrestha, Anjana Singh
BACKGROUND: Lower respiratory tract infection is a common cause of morbidity and mortality worldwide. A cross-sectional study was carried out with an objective to study the antibiogram of Gram-negative isolates of patients with lower respiratory tract infection visiting Kathmandu Model Hospital. METHODS: A total of 274 specimens including sputum, endotracheal aspirates, suction tips were cultured as per standard microbiological technique. Antibiotic susceptibility and detection of Extended-spectrum beta- lactamases (ESBLs) were performed following Clinical Laboratory Standard Institute (CLSI 2014) guidelines...
March 13, 2018: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/29705517/crossing-the-roof-of-the-world-trade-in-medicinal-plants-from-nepal-to-china
#12
Jun He, Bin Yang, Min Dong, Yunshang Wang
ETHNOPHARMACOLOGICAL RELEVANCE: Trade in medicinal and aromatic plants (MAPs) between Nepal and China has taken place for centuries along the Tibetan border. While there is anecdotal evidence that economic development in China over the past decades, coupled with regional infrastructure development and increasing market integration, has substantially changed this trade, there are no current published studies investigating this, e.g. in terms of species and market structure. This knowledge gap impedes the development of public interventions, e...
April 26, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29702658/use-of-weighted-multivariate-estimates-in-trials-of-multi-serotype-vaccines-to-simplify-interpretation-of-treatment-differences
#13
Merryn Voysey, Andrew J Pollard, Rafael Perera, Shrijana Shrestha, Stephen Thorson, Thomas R Fanshawe
BACKGROUND: Many vaccines contain multiple components. Licensed pneumococcal conjugate vaccines (PCV) contain polysaccharides from 7, 10, or 13 different serotypes of Streptococcus pneumoniae. The main outcomes in randomised trials of pneumococcal vaccines are serotype-specific antibody measures. Comparisons are made between groups for each serotype, resulting in multiple separate comparisons of treatment effects which can be complicated to interpret. We investigated methods for computing the overall difference between vaccine groups across all serotypes...
2018: PloS One
https://www.readbyqxmd.com/read/29691837/oral-health-status-associated-with-sociodemographic-factors-of-nepalese-schoolchildren-a-population-based-study
#14
Saujanya Karki, Marja-Liisa Laitala, Manoj Humagain, Marjo Seppänen, Jari Päkkila, Vuokko Anttonen
OBJECTIVES: The aim of this study was to investigate the oral health of Nepalese schoolchildren relative to their sociodemographic characteristics. METHODS: This school-based, cross-sectional study was conducted among 5-6-, 12- and 15-year-old Nepalese children in 18 randomly selected districts of the 75 in Nepal. Clinical parameters were recorded according to the World Health Organization (WHO) guidelines. Results were presented as mean (SD) and proportions; the chi-square test, t-test and one way-ANOVA were also performed...
April 25, 2018: International Dental Journal
https://www.readbyqxmd.com/read/29687287/quantifying-the-connections-linkages-between-land-use-and-water-in-the-kathmandu-valley-nepal
#15
Jeffrey C Davids, Martine M Rutten, Ram Devi T Shah, Deep N Shah, Nischal Devkota, Petra Izeboud, Anusha Pandey, Nick van de Giesen
Land development without thoughtful water supply planning can lead to unsustainability. In practice, management of our lands and waters is often unintegrated. We present new land-use, ecological stream health, water quality, and streamflow data from nine perennial watersheds in the Kathmandu Valley, Nepal, in the 2016 monsoon (i.e., August and September) and 2017 pre-monsoon (i.e., April and May) periods. Our goal was to improve understanding of the longitudinal linkages between land-use and water. At a total of 38 locations, the Rapid Stream Assessment (RSA) protocol was used to characterize stream ecology, basic water quality parameters were collected with a handheld WTW multi-parameter meter, and stream flow was measured with a SonTek FlowTracker Acoustic Doppler Velocimeter...
April 23, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29679435/validation-of-host-specific-bacteroidales-quantitative-pcr-assays-and-their-application-to-microbial-source-tracking-of-drinking-water-sources-in-the-kathmandu-valley-nepal
#16
B Malla, R Ghaju Shrestha, S Tandukar, D Bhandari, D Inoue, K Sei, Y Tanaka, J B Sherchand, E Haramoto
AIMS: To validate host-specific Bacteroidales assays to identify faecal-source contamination of drinking water sources in the Kathmandu Valley, Nepal. METHODS AND RESULTS: A total of 54 composite faecal-source samples were collected from human sewage, ruminants, pigs, dogs, chickens and ducks, which were analysed by quantitative polymerase chain reaction using human-specific (BacHum, HF183 SYBR, gyrB and HF183 TaqMan), ruminant-specific (BacCow and BacR), pig-specific (Pig2Bac and PF163) and dog-specific assays (BacCan SYBR)...
April 20, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29670804/blood-transfusion-practice-among-healthcare-personnel-in-nepal-an-observational-study
#17
Abja Sapkota, Sabitra Poudel, Arun Sedhain, Niru Khatiwada
Background: The complications associated with errors in transfusion practice can be minimized by assessing transfusion practices. In Nepal, there is no standard protocol on blood transfusion. So, this study was conducted with an aim to assess the blood transfusion practice among healthcare personnel. Methods: A descriptive observational study was conducted in two tertiary hospitals in Kathmandu, Nepal, over a period of 10 months. Bedside blood transfusion procedures were observed using structured checklist...
2018: Journal of Blood Transfusion
https://www.readbyqxmd.com/read/29668933/the-human-clone-st22-sccmec-iv-methicillin-resistant-staphylococcus-aureus-isolated-from-swine-herds-and-wild-primates-in-nepal-is-man-the-common-source
#18
Marilyn C Roberts, Prabhu Raj Joshi, Alexander L Greninger, Daira Melendez, Saroj Paudel, Mahesh Acharya, Nabin Kishor Bimali, Narayan P Koju, David No, Mukesh Chalise, Randall C Kyes
Swine nasal samples [n = 282] were collected from 12 randomly selected farms around Kathmandu, Nepal, from healthy animals. In addition, wild monkey (Macaca mulatta) saliva samples [n = 59] were collected near temples areas in Kathmandu using a non-invasive sampling technique. All samples were processed for MRSA using standardized selective media and conventional biochemical tests. MRSA verification was done and isolates characterized by SCCmec, multilocus sequence typing, whole genome sequencing [WGS] and antibiotic susceptibilities...
May 1, 2018: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29622996/clinical-profile-management-and-outcome-of-pulmonary-embolism-in-shahid-gangalal-national-heart-centre-kathmandu-nepal
#19
Chandra Mani Adhikari, K C Bishal, Sobita Khadka
Background and aims: Pulmonary embolism (PE) is associated with a significant mortality and morbidity. We aim to study clinical profile, management and outcome of PE at Shahid Gangalal National heart Centre, Kathmandu, Nepal. Methods: It was a retrprospective, single centre study, conducted from January 2015 to December 2016. Haemodynamics was used for risk Simplified, PESI score, predisposing factors, symptoms, clinical features at the time of admission, ECG features, echocardiogram, treatment received and the outcome were reviewed...
March 2018: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29617832/challenges-constraining-insulin-access-in-nepal-a-country-with-no-local-insulin-production
#20
Abhishek Sharma, Parash Mani Bhandari, Dipika Neupane, Warren A Kaplan, Shiva Raj Mishra
Background: Nepal is facing an increasing burden of diabetes and relies almost entirely on insulin imported through India. Methods: We employed a modified version of the WHO/Health Action International standard survey to assess insulin availability and prices, along with qualitative interviews with insulin retailers (pharmacists) and wholesalers in the Kathmandu Valley, Nepal. Results: The mean availability of the two human insulins listed on the 2011 Nepal Essential Medicine List were 14...
May 1, 2018: International Health
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