keyword
MENU ▼
Read by QxMD icon Read
search

Cravings

keyword
https://www.readbyqxmd.com/read/28933254/the-efficacy-of-a-working-memory-training-in-substance-use-patients-a-randomized-double-blind-placebo-controlled-clinical-trial
#1
Sabine Wanmaker, Sophie Maaike Jorinde Leijdesdorff, Elke Geraerts, Ben J M van de Wetering, Peter J Renkema, Ingmar H A Franken
INTRODUCTION: Substance use disorder patients show impairments in working memory (WM) functioning. Previous findings indicate that a WM training results in improvements of working memory capacity (WMC) and in decreased clinical symptoms in a range of mental disorders, including alcohol use disorder. METHOD: The aim of the current study is to investigate the efficacy of a 24-session WM training in addition to treatment as usual on craving, WMC, substance use, impulsivity, attention bias, and psychopathology using a randomized double-blind placebo-controlled trial...
September 21, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28931433/role-of-gabaa-receptors-in-alcohol-use-disorders-suggested-by-chronic-intermittent-ethanol-cie-rodent-model
#2
REVIEW
Richard W Olsen, Jing Liang
GABAergic inhibitory transmission is involved in the acute and chronic effects of ethanol on the brain and behavior. One-dose ethanol exposure induces transient plastic changes in GABAA receptor subunit levels, composition, and regional and subcellular localization. Rapid down-regulation of early responder δ subunit-containing GABAA receptor subtypes mediating ethanol-sensitive tonic inhibitory currents in critical neuronal circuits corresponds to rapid tolerance to ethanol's behavioral responses. Slightly slower, α1 subunit-containing GABAA receptor subtypes mediating ethanol-insensitive synaptic inhibition are down-regulated, corresponding to tolerance to additional ethanol behaviors plus cross-tolerance to other GABAergic drugs including benzodiazepines, anesthetics, and neurosteroids, especially sedative-hypnotic effects...
September 20, 2017: Molecular Brain
https://www.readbyqxmd.com/read/28927321/do-current-and-former-cigarette-smokers-have-an-attentional-bias-for-e-cigarette-cues
#3
Kirsten Lochbuehler, E Paul Wileyto, Kathy Z Tang, Melissa Mercincavage, Joseph N Cappella, Andrew A Strasser
The similarity of e-cigarettes to tobacco cigarettes with regard to shape and usage raises the question of whether e-cigarette cues have the same incentive motivational properties as tobacco cigarette cues. The objective of the present study was to examine whether e-cigarette cues capture and hold smokers' and former smokers' attention and whether the attentional focus is associated with subsequent craving for tobacco cigarettes. It was also examined whether device type (cigalike or mod) moderated this relationship...
September 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28926762/progesterone-for-smoking-relapse-prevention-following-delivery-a-pilot-randomized-double-blind-study
#4
Ariadna Forray, Kathryn Gilstad-Hayden, Cristine Suppies, Debra Bogen, Mehmet Sofuoglu, Kimberly A Yonkers
INTRODUCTION: Close to half of women who were smokers prior to conception quit smoking in pregnancy, when endogenous progesterone levels are high. However, at least half resume pre-pregnancy smoking levels within weeks after delivery and when progesterone levels drop. The current pilot study tested the feasibility and preliminary efficacy of postpartum progesterone replacement in preventing relapse to smoking in postpartum women with a history of pre-pregnancy smoking. METHODS: This was an 8-week, double-blind, parallel, randomized, placebo-controlled pilot trial of 41 women with a history of pre-pregnancy smoking who achieved abstinence by 32 weeks of gestation...
September 14, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28925882/why-are-antidepressant-drugs-effective-smoking-cessation-aids
#5
Mohammed Shoaib, Yazead Buhidma
Before the advent of varenicline, antidepressant drugs were reported to exhibit better clinical efficacy than nicotine replacement therapy as smoking cessation aids. The most studied is bupropion, a clinically-effective antidepressant, the first to be marketed throughout Europe for smoking cessation. The mechanisms behind bupropion's efficacy as a smoking cessation compound remains unclear. Since depression and tobacco smoking have a high incidence of co-occurrence, this would implicate an underlying link between these two conditions...
September 15, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28923899/cardiovascular-risk-factors-accelerate-progression-of-vascular-aging-in-the-general-population-results-from-the-crave-study-cardiovascular-risk-factors-affecting-vascular-age
#6
Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Panagiotis Xaplanteris, Nikolaos Ioakeimidis, Konstantinos Aznaouridis, Katerina Baou, Despina Kardara, Georgios Georgiopoulos, Christos Georgakopoulos, Dimitrios Tousoulis
Vascular aging, as assessed by structural and functional arterial properties, is an independent predictor of cardiovascular risk. We hypothesized that the number of cardiovascular risk factors determines the progression of vascular aging. One hundred forty-two subjects (mean age 51.9 years, 94 men) without established cardiovascular disease were investigated in 2 examinations over a 2-year period. Subjects were classified at baseline according to their number of risk factors (from 0 to 2 and more). Subjects had determinations of carotid-femoral pulse wave velocity, aortic augmentation index, brachial flow-mediated dilatation, and common carotid intima-media thickness and their annual absolute changes were calculated...
September 18, 2017: Hypertension
https://www.readbyqxmd.com/read/28922968/the-effect-of-n-acetylcysteine-on-brain-glutamate-and-gamma-aminobutyric-acid-concentrations-and-on-smoking-cessation-a-randomized-double-blind-placebo-controlled-trial
#7
Mhj Schulte, A E Goudriaan, A M Kaag, D P Kooi, W van den Brink, R W Wiers, L Schmaal
Using data form a 14-day double-blind trial with 48 smokers randomized to either N-acetylcysteine (2400 mg) or placebo, we tested the effect of N-acetylcysteine on glutamate and gamma-aminobutyric acid concentrations in the dorsal anterior cingulate cortex and on smoking cessation. Smoking related behaviors and neurotransmitter concentrations in the dorsal anterior cingulate cortex were assessed before and after treatment. Forty-seven non-smoking males served as baseline controls. Smokers showed higher baseline glutamate but similar gamma-aminobutyric acid concentrations than non-smokers...
September 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28922651/evaluating-the-effect-of-smoking-cessation-treatment-on-a-complex-dynamical-system
#8
Korkut Bekiroglu, Michael A Russell, Constantino M Lagoa, Stephanie T Lanza, Megan E Piper
OBJECTIVE: To understand the dynamic relations among tobacco withdrawal symptoms to inform the development of effective smoking cessation treatments. Dynamical system models from control engineering are introduced and utilized to evaluate complex treatment effects. We demonstrate how dynamical models can be used to examine how distinct withdrawal-related processes are related over time and how treatment influences these relations. METHOD: Intensive longitudinal data from a randomized placebo-controlled smoking cessation trial (N=1504) are used to estimate a dynamical model of withdrawal-related processes including momentary craving, negative affect, quitting self-efficacy, and cessation fatigue for each of six treatment conditions (nicotine patch, nicotine lozenge, bupropion, patch + lozenge, bupropion + lozenge, and placebo)...
August 25, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28922195/dispositional-mindful-attention-in-relation-to-negative-affect-tobacco-withdrawal-and-expired-carbon-monoxide-on-and-after-quit-day
#9
Daniel J Paulus, Kirsten J Langdon, David W Wetter, Michael J Zvolensky
BACKGROUND: Mindfulness (or "Mindful Attention") has been described as the presence or absence of attention to, and awareness of, what is occurring in the present moment. Among smokers, greater mindfulness is associated with greater effect stability and reduced cue-induced craving. While studies have shown that mindfulness is associated with other smoking-related factors such as reduced withdrawal symptoms using cross-sectional data, relatively little is known about the associations between baseline mindful attention and future abstinence-related effect/withdrawal...
September 15, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28921814/nabilone-pharmacotherapy-for-cannabis-dependence-a-randomized-controlled-pilot-study
#10
Kevin P Hill, Matthew D Palastro, Staci A Gruber, Garrett M Fitzmaurice, Shelly F Greenfield, Scott E Lukas, Roger D Weiss
BACKGROUND AND OBJECTIVES: We assessed the safety, tolerability, and preliminary efficacy of nabilone, a cannabinoid agonist, to treat cannabis dependence. METHODS: Eighteen adults with DSM-IV cannabis dependence were randomized to receive either 2 mg/day of nabilone (n = 10) or placebo (n = 8) for 10 weeks in addition to medication management. Twelve participants, six in each group, completed treatment. The safety and tolerability of nabilone was assessed at each visit...
September 18, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28920590/incubation-of-accumbal-neuronal-reactivity-to-cocaine-cues-during-abstinence-predicts-individual-vulnerability-to-relapse
#11
Karine Guillem, Serge H Ahmed
An important goal for the treatment of cocaine addiction is to identify neuromarkers that can predict individual vulnerability to relapse after abstinence. There is some evidence that individual reactivity to cue-induced craving may predict subsequent relapse after a period of abstinence. Here we sought to identify the neuronal correlates of this predictive relationship in rats. Rats were trained to self-administer cocaine (6-h) for 16 days to induce escalation of cocaine intake. Then rats underwent a 1-month period of forced abstinence after which they were re-exposed to cocaine self-administration (6-h) for 8 additional days to induce re-escalation of cocaine intake...
September 18, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28919834/substance-use-disorders-in-military-veterans-prevalence-and-treatment-challenges
#12
REVIEW
Jenni B Teeters, Cynthia L Lancaster, Delisa G Brown, Sudie E Back
Substance use disorders (SUDs) are a significant problem among our nation's military veterans. In the following overview, we provide information on the prevalence of SUDs among military veterans, clinical characteristics of SUDs, options for screening and evidence-based treatment, as well as relevant treatment challenges. Among psychotherapeutic approaches, behavioral interventions for the management of SUDs typically involve short-term, cognitive-behavioral therapy interventions. These interventions focus on the identification and modification of maladaptive thoughts and behaviors associated with increased craving, use, or relapse to substances...
2017: Substance Abuse and Rehabilitation
https://www.readbyqxmd.com/read/28918456/testing-a-mobile-mindful-eating-intervention-targeting-craving-related-eating-feasibility-and-proof-of-concept
#13
Ashley E Mason, Kinnari Jhaveri, Michael Cohn, Judson A Brewer
Theoretically driven smartphone-delivered behavioral interventions that target mechanisms underlying eating behavior are lacking. In this study, we administered a 28-day self-paced smartphone-delivered intervention rooted in an operant conditioning theoretical framework that targets craving-related eating using mindful eating practices. At pre-intervention and 1-month post-intervention, we assessed food cravings among adult overweight or obese women (N = 104; M age = 46.2 ± 14.1 years; M BMI = 31...
September 16, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28917098/can-attitudes-about-smoking-impact-cigarette-cravings
#14
Lauren Bertin, Samara Lipsky, Joel Erblich
Cigarette cravings, especially those in response to environmental stressors and other smoking-related triggers (e.g., passing by a favorite smoking spot), are important contributors to smoking behavior and relapse. Previous studies have demonstrated significant individual differences in such cravings. This study explores the possibility that attitudes about smoking can influence the experience of cigarette craving. Consistent with classical theories of the links between cognition and motivation, we predicted that smokers who exhibit more favorable attitudes towards smoking would have greater cravings...
September 8, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28910232/characterizing-blunt-use-among-twitter-users-racial-ethnic-differences-in-use-patterns-and-characteristics
#15
LaTrice Montgomery, Kamonta Heidelburg, Cendrine Robinson
BACKGROUND: Young adult Twitter users are exposed to and often participate in tweets that promote risky behaviors, such as blunt use. Blunts are hollowed out cigars or cigarillos that are filled with marijuana. OBJECTIVES: The current study was designed to determine the use patterns and characteristics of African American, Hispanic and White young adult Twitter users who reported past month blunt use. METHODS: Young adults (N = 753, 74% male) who reported past month blunt use were recruited via Twitter to participate in a brief anonymous online survey about their blunt use...
September 14, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28901656/the-effects-of-seasonal-affective-disorder-and-alcohol-abuse-on-sleep-and-snoring-functions-in-a-population-based-study-in-finland
#16
Isabel Morales-Muñoz, Seppo Koskinen, Timo Partonen
Seasonal affective disorder (SAD) is a recurrent depressive disorder with a seasonal pattern. In addition to some specific symptoms such as sad mood, low energy or carbohydrate craving, this mood disorder is also characterized by the presence of sleeping problems and alcohol disorders. Interestingly, there is a strong link between alcohol use and sleeping deficits. Although previous studies have focused extensively on the sleep patterns in SAD patients and patients with alcohol use disorder (AUD), no research has yet been conducted on subjects with comorbid SAD and AUD...
September 13, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28898494/n-acetylcysteine-in-the-treatment-of-craving-in-substance-use-disorders-systematic-review-and-meta-analysis
#17
Michel Silvio Duailibi, Quirino Cordeiro, Elisa Brietzke, Marcelo Ribeiro, Steve LaRowe, Michael Berk, Alisson Paulino Trevizol
BACKGROUND AND OBJECTIVES: Recent neurobiological evidences along with clinical observations justify the use of N-acetylcysteine (NAC) as a medication for craving. The objective of our study was to assess the evidence of efficacy of NAC for craving in substance use disorders in randomized clinical trials (RCTs). METHODS: Systematic review of the RCTs literature (PROSPERO number 56698) until February, 2017, using MEDLINE, Cochrane Library and clinicaltrials.gov. We included seven RCTs (n = 245); most with small-to-moderate sample sizes...
September 12, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28898485/transcranial-magnetic-stimulation-of-the-dorsal-lateral-prefrontal-cortex-inhibits-medial-orbitofrontal-activity-in-smokers
#18
Xingbao Li, Gregory L Sahlem, Bashar W Badran, Lisa M McTeague, Colleen A Hanlon, Karen J Hartwell, Scott Henderson, Mark S George
BACKGROUND AND OBJECTIVE: Several studies have shown that repetitive transcranial magnetic stimulation (rTMS), applied to the dorsolateral prefrontal cortex (DLPFC), can reduce cue-elicited craving in smokers. Currently, the mechanism of this effect is unknown. We used functional magnetic resonance imaging (fMRI) to explore the effect of a single treatment of rTMS on cortical and sub-cortical neural activity in non-treatment seeking nicotine-dependent participants. METHODS: We conducted a randomized, counterbalanced, crossover trial in which participants attended two experimental visits separated by at least 1 week...
September 12, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28898308/-the-treatment-of-cannabis-dependence-clinical-work-psychotherapy-and-evidence
#19
José Capece, Federico Pavlovsky
Identifying compulsive consumption of marijuana in association with another mental disorder (attentional defcit disorder, bipolar disorder, depression or psychosis) presents the challenge of clarifying validated therapeutic strategies, especially within the teen population, in which it shows the highest prevalence. The ever-increasing prevalence and the need for regional treatments, demand that we approach this health matter as a public health issue. The ideological con?icts related to the necessary decriminalization of consumption and the current debate on the medical use of marijuana often confuse the urgent need to establish effective therapeutic strategies for the population affected by this mental disorder...
November 2016: Vertex: Revista Argentina de Psiquiatriá
https://www.readbyqxmd.com/read/28894547/a-novel-therapy-for-cocaine-dependence-during-abstinence-a-randomized-clinical-trial
#20
Bijan Pirnia, Ali Reza Moradi, Kambiz Pirnia, Parisa Kolahi, Rasool Roshan
BACKGROUND: Topiramate is an anticonvulsant drug and an ideal candidate for reducing the craving in people relying on cocaine. Contingency management is one of the common therapies in the domain of addiction. OBJECTIVE: The present study aimed to evaluate and compare three medication methods of Topiramate (TPM), Contingency Management (CM) and the combined TPM treatment and cash intervention on craving during abstinence. METHODS: This randomized clinical trial was conducted at Bijan Center for Substance Abuse Treatment in Tehran, Iran, from December 15, 2014 to November 20, 2015...
July 2017: Electronic Physician
keyword
keyword
25263
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"