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https://www.readbyqxmd.com/read/28645120/acute-abdomen-secondary-to-ruptured-epithelial-ovarian-cancer-during-pregnancy-the-relevance-of-teamwork
#1
Carlos Manuel Ortiz-Mendoza, Sandra Adriana Vera-Vázquez, Manuel Gómez-Rodríguez, José Luis López-Gómez, Leticia Bornstein-Quevedo
Acute abdomen secondary to epithelial ovarian cancer rupture during pregnancy is a rare event. Our aim is to present how the work of a coordinated multidisciplinary team in a case of ruptured epithelial ovarian cancer during pregnancy is feasible to obtain the best results possible. A 34-year-old woman during the 37th week of her first gestation presented with an acute abdomen. During laparotomy, a ruptured 16.5-cm left ovarian tumor was detected; the tumor was extirpated and sent to pathologic evaluation. In the meantime, a Kerr cesarean section was performed, and a healthy female neonate was born...
June 23, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28644128/intraductal-cisplatin-treatment-in-a-brca-associated-breast-cancer-mouse-model-attenuates-tumor-development-but-leads-to-systemic-tumors-in-aged-female-mice
#2
Jolien S de Groot, Paul J van Diest, Miranda van Amersfoort, Eva J Vlug, Xiaojuan Pan, Natalie D Ter Hoeve, Hilde Rosing, Jos H Beijnen, Sameh A Youssef, Alain de Bruin, Jos Jonkers, Elsken van der Wall, Patrick W B Derksen
BRCA deficiency predisposes to the development of invasive breast cancer. In BRCA mutation carriers this risk can increase up to 80%. Currently, bilateral prophylactic mastectomy and prophylactic bilateral salpingo-oophorectomy are the only preventive, albeit radical invasive strategies to prevent breast cancer in BRCA mutation carriers. An alternative non-invasive way to prevent BRCA1-associated breast cancer may be local prophylactic treatment via the nipple.Using a non-invasive intraductal (ID) preclinical intervention strategy, we explored the use of combined cisplatin and poly (ADP)-ribose polymerase 1 (PARP1) inhibition to prevent the development of hereditary breast cancer...
June 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28643020/association-between-lifestyle-menstrual-reproductive-history-and-histological-factors-and-risk-of-breast-cancer-in-women-biopsied-for-benign-breast-disease
#3
Rhonda Arthur, Yihong Wang, Kenny Ye, Andrew G Glass, Mindy Ginsberg, Olivier Loudig, Thomas Rohan
PURPOSE: Women with benign breast disease (BBD) have an increased risk of subsequent breast cancer. However, whether conventional breast cancer risk factors influence risk of breast cancer among women with BBD is unclear. In this study, we investigated the associations of lifestyle, menstrual/reproductive, and histological factors with risk of breast cancer among women biopsied for BBD. METHODS: We conducted a case-control study, nested within a cohort of 15,395 women biopsied for BBD at Kaiser Permanente Northwest between 1971 and 2006...
June 22, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28642025/total-laparoscopic-resection-surgery-for-a-cervical-carcinoma-that%C3%A2-recurred-in-the-pelvic-sidewall-after-radical-hysterectomy-and%C3%A2-adjuvant-concurrent-chemoradiotherapy
#4
Hiroyuki Kanao, Yoichi Aoki, Kazuyoshi Kato, Maki Matoda, Sanshiro Okamoto, Hidetaka Nomura, Kohei Omatsu, Kuniko Utsugi, Nobuhiro Takeshima
STUDY OBJECTIVE: To show total laparoscopic resection of a cervical carcinoma that recurred at the left pelvic sidewall after radical hysterectomy and concurrent chemoradiotherapy (CCRT). DESIGN: A step-by-step demonstration of the technique in a surgical video, including the strategy for achieving complete surgical resection with negative margins (R0 resection) (Canadian Task Force Classification III). SETTING: For high-risk cervical carcinoma, radical hysterectomy and adjuvant CCRT is the standard treatment, but even this multimodal therapy cannot prevent recurrence...
June 19, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28633616/sclerosing-stromal-tumor-mimicking-a-pregnancy-luteoma-case-report-of-a-diagnostically-challenging-entity-further-complicated-by-the-presence-of-metastatic-signet-ring-cell-carcinoma-from-the-stomach
#5
Meral Uner, Alp Usubutun
Sclerosing stromal tumors of the ovary are very rare. We report the case of a 29-year-old pregnant woman who presented with a history of preterm labor and gestational hypertension. A huge mass measuring 30 cm in greatest dimension was recognized on the right ovary during cesarean section. Signet ring cell infiltration was seen during intraoperative frozen section consultation. She underwent a right salpingo-oophorectomy, and the permanent diagnosis was sclerosing stromal tumor infiltrated by signet ring cells...
June 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28631536/should-ovaries-be-removed-or-not-in-early-stage-cervical-adenocarcinoma-a-multicenter-retrospective-study-of-105-patients
#6
Jun Hu, Xiaobing Jiao, Zhifeng Yang, Heng Cui, Hongyan Guo, Yumei Wu, Lirong Zhu
The study population consisted of 105 patients with stage IA to IIB cervical adenocarcinoma (AC) who underwent radical hysterectomy and pelvic lymphadenectomy from three institutions between 1994 and 2015, including 86 patients with bilateral salpingo-oophorectomy (BSO) and 19 patients with ovarian preservation operation. Ovarian metastasis were diagnosed in 3 of 86 patients in BSO group with an incidence rate of 3.5% (3/86). Among the 19 patients with ovarian preservation, none developed an ovarian recurrence in the follow-up (2-71 months)...
June 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28626261/a-case-of-metachronous-left-ovarian-metastasis-8-years-after-surgery-for-cecal-cancer-and-right-ovarian-metastasis-report-of-a-case
#7
Itaru Shigeyoshi, Koji Komori, Takashi Kinoshita, Taihei Oshiro, Seiji Ito, Tetsuya Abe, Yoshiki Senda, Kazunari Misawa, Yuichi Ito, Norihisa Uemura, Seiji Natsume, Jiro Kawakami, Akira Ouchi, Masayuki Tsutsuyama, Takahiro Hosoi, Tomoyuki Akazawa, Daisuke Hayashi, Hideharu Tanaka, Yasushi Yatabe, Yasuhiro Shimizu
Metachronous ovarian metastasis of colorectal adenocarcinoma is mostly identified within 3 years. Here we present a case of a 64-year-old woman with cecal cancer who underwent right oophorectomy for ovarian metastasis. Imaging was performed because of abdominal bloating; it detected a swollen right ovary with ascites. On laparotomy, a right ovarian tumor and cecal cancer were identified. After right oophorectomy, a diagnosis of unilateral ovarian metastasis from colon cancer was made. One month later, right hemicolectomy was performed...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28624984/the-senhance%C3%A2-surgical-robotic-system-senhance-for-total-hysterectomy-in-obese-patients-a-pilot-study
#8
Salvatore Gueli Alletti, C Rossitto, S Cianci, E Perrone, S Pizzacalla, G Monterossi, G Vizzielli, S Gidaro, G Scambia
This pilot study was aimed to value the feasibility and safety of Senhance Robotic Platform for hysterectomy in obese patients. Ten obese patients (30 < BMI < 40) underwent elective Senhance total extrafascial hysterectomy with bilateral salpingo-oophorectomy at the Division of Gynecologic Oncology of "Policlinico A. Gemelli" Foundation, Rome, Italy. Perioperative and postoperative outcomes data were recorded. The median age was 60 years (range 51-75) and the median BMI was 33.3 kg/m(2) (range 30...
June 17, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28622261/pelvic-pain-in-transgender-men-taking-testosterone-assessing-the-risk-of-ovarian-cancer
#9
Miles Harris, Lauren Kondel, Caroline Dorsen
Some guidelines on care for transgender men taking testosterone recommend oophorectomy to prevent ovarian cancer, while others recommend following guidelines for females. A review of the literature finds no strong evidence that transgender men are at increased risk for ovarian cancer. In transgender men taking testosterone without other risk factors, oophorectomy to prevent cancer is unnecessary.
July 15, 2017: Nurse Practitioner
https://www.readbyqxmd.com/read/28621691/ovarian-preservation-improves-overall-survival-in-young-patients-with-early-stage-endometrial-cancer
#10
REVIEW
Peng Jia, Yan Zhang
We searched Medline, Embase, Cochrane library, the Chinese Biomedicine Literature Database, the Chinese Scientific Journal Full-text Database, the Chinese Journal Full-text Database, and the Wanfang Database to collect observational studies on the effects of ovary-saving surgery in comparison to bilateral salpingo-oophorectomy (BSO) in young patients with early-stage endometrial cancer (EC). The literature search included studies up to March 2017, and 10 retrospective cohort studies met our selection criteria...
June 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28619976/vesical-dermoid-a-rare-bladder-tumour
#11
Ashok Kumar Sokhal, Bhupendra Pal Singh, Sunny Goel, Durgesh Kumar Saini
Dermoid cysts are benign developmental lesions consisting of tissues of more than one germ cell lineage origin. The urinary bladder is a very rare location of dermoid cysts. We report a case of an 18-year-old woman who presented with suprapubic pain, dysuria and turbid urine. Blood and serum chemistry was normal. Contrast-enhanced CT revealed a heterogeneously enhancing mass of 2.5×2 cm within the urinary bladder infiltrating fundus of urinary bladder with extraluminal extension. At cystoscopy, an irregular mass arising from the dome of the urinary bladder with a covering of hair and whitish scales was seen...
June 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28616156/primary-solitary-peritoneal-tumor-of-the-abdominal-wall-report-of-a-rare-case-and-review-of-the-literature
#12
Christoforos Efthimiadis, Aristeidis Ioannidis, Konstantinia Kofina, Marios Grigoriou
Abdominal wall tumors are sometimes diagnosed as metastases of ovarian cancer, however, primary peritoneal tumors should be taken into consideration in the final diagnosis. A 49-year-old female patient was admitted in our Department for the excision of a pulpable abdominal wall lump, with no other abnormalities shown on imaging investigation. On histology examination, the excised specimen revealed characteristics of metastatic high-grade serous ovarian carcinoma. Total hysterectomy, bilateral oophorectomy, omentectomy and appendectomy were performed...
June 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28610900/persistence-of-fimbrial-tissue-on-the-ovarian-surface-following-salpingectomy
#13
Carmen Gan, Rashna Chenoy, Dhivya Chandrasekaran, Elly Brockbank, Antony Hollingworth, Sotiris Vimplis, Alexandra C Lawrence, Arjun R Jeyarajah, David Oram, Nandita Deo, Jamna Saravanamuthu, Sarah S Lam, Asma Faruqi, Naveena Singh, Ranjit Manchanda
BACKGROUND: Salpingectomy is recommended as a risk-reducing strategy for epithelial tubo-ovarian cancer. The gold standard procedure is complete tubal excision. OBJECTIVE: To assess the presence of residual fimbrial/tubal tissue on ovarian surfaces following salpingectomy. DESIGN: Prospective analysis of patients undergoing salpingo-oophorectomy +/- hysterectomy for benign indications, early cervical cancer or low risk endometrial cancer at a UK National Health Service Trust...
June 10, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28609281/ectopic-ovarian-pregnancy-after-intracytoplasmic-sperm-injection-with-testicular-spermatozoa-a-case-report
#14
Javier García-Ferreyra, Roly Hilario, Julio Dueñas
Ovarian ectopic pregnancy is a rare event in both natural and assisted human reproduction settings. There are few reports of this event after in vitro fertilization. Diagnosis can be challenging, since it requires specific medical expertise. Patients with this condition call for careful management during treatment so as to not affect their fertility potential. This paper describes the case of a woman submitted to ICSI and embryo transfer who subsequently had an ovarian ectopic pregnancy and underwent a laparoscopic partial right oophorectomy...
June 1, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28609271/viability-of-homologous-and-heterologous-subcutaneous-transplantation-of-fresh-germ-cells-in-rabbits
#15
Paula M A Cerialle, Carlos G Almodin, Moacir R M Radaelli, Vânia C Minguetti-Câmara, Michelle C Souza, Carlos A M Oliveira, Antonio J Gonçalves
OBJECTIVE: This study aimed to compare heterologous to homologous transplantation of fresh ovarian germ cells in rabbits. METHODS: Twelve female white New Zealand rabbits (Oryctolagus cuniculus) were randomly numbered and submitted to bilateral oophorectomies. The ovaries from the six odd-numbered rabbits were dissected and cortical germinal tissue was digested in collagenase type 1 to obtain six solutions containing stromal and germ cells, which were injected in the abdominal region of the odd-numbered rabbits themselves (homologous transplantation) and of the even-numbered rabbits (heterologous transplantation) off immunosuppression...
June 1, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28607282/laparoendoscopic-single-site-adnexal-surgery-preliminary-indian-experience
#16
Smitha Balusamy, Hrishikesh P Salgaonkar, Ramya Ranjan Behera, Ashwini Bhalerao-Gandhi, Deepraj S Bhandarkar
INTRODUCTION: Laparoendoscopic single-site surgery (LESS) is an emerging technique in gynaecology. The proposed advantages of the LESS include better cosmesis and reduction in pain. We report our preliminary experience with LESS in the treatment of adnexal pathology. MATERIALS AND METHODS: After a preoperative workup, LESS was offered to 37 patients between July 2009 and April 2015. All the procedures were carried out through a 2-2.5 cm transumbilical incision using conventional laparoscopic instruments...
July 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28604455/oncologic-outcomes-after-adjuvant-radiotherapy-for-stage-ii-endometrial-carcinoma-a-korean-radiation-oncology-group-study-krog-14-10
#17
Jinhong Jung, Young Seok Kim, Ji Hyeon Joo, Won Park, Jong-Hoon Lee, Jin Hee Kim, Won Sup Yoon, Seok-Ho Lee, Keun-Yong Eom, Yong Bae Kim
OBJECTIVE: The aim of this study was to investigate the survival, patterns of failure, and prognostic factors in patients with stage II endometrial carcinoma treated with adjuvant radiotherapy. METHODS: We reviewed the medical records of patients who underwent total hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymph node dissection followed by adjuvant radiotherapy in 10 participating hospitals of the Korean Radiation Oncology Group. Most patients received adjuvant external beam radiation therapy, with a median dose of 50...
June 10, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28604129/severe-hyperandrogenemia-in-postmenopausal-woman-as-a-presentation-of-ovarian-hyperthecosis-case-report-and-mini-review-of-the-literature
#18
Adam Czyzyk, Justyna Latacz, Dorota Filipowicz, Agnieszka Podfigurna, Rafal Moszynski, Piotr Jasinski, Stefan Sajdak, Michal Gaca, Andrea R Genazzani, Blazej Meczekalski
Ovarian hyperthecosis (OH) is characterized by the presence of abundant luteinized theca cells in ovaries that secret androgen. It typically presents as severe hyperandrogenism and/or virilization in postmenopausal woman. Here we describe a 66-year old woman with presentation of severe hirsutism, alopecia, clitoromegaly and laboratory finding of significantly elevated serum total testosterone concentration and hyperinsulinemia. Performed imaging studies revealed normal sized, homogeneous ovaries, signs of endometrial hypertrophy and normal adrenal glands...
June 11, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28602465/the-management-of-sexuality-intimacy-and-menopause-symptoms-sims-after-prophylactic-bilateral-salpingo-oophorectomy-how-to-maintain-sexual-health-in-previvors
#19
REVIEW
Mehida Alexandre, Jonathan Black, Margaret Whicker, Mary Jane Minkin, Elena Ratner
"Previvors", or "pre-survivors", are individuals who do not have cancer but have a genetic predisposition to cancer. One such example is women with BRCA mutations. As a result of their predisposition to cancer, many will undergo a bilateral salpingo-oophorectomy when they are premenopausal. For premenopausal women, the removal of ovaries results in the depletion of estrogen, immediate menopause, and, in many cases, resultant Sexuality, Intimacy, and Menopausal Symptoms (SIMS). Furthermore, they may undergo changes in body image...
June 3, 2017: Maturitas
https://www.readbyqxmd.com/read/28600055/recurrent-female-adnexal-tumor-of-probably-wolffian-origin-a-case-report
#20
Tian Qiu, Yincheng Teng, Jianqian Tong, Wenqi Tao, Liang Xu
OBJECTIVE: Wolffian adnexal tumors (WATs) are rare, and metastasis is uncommon. We present the case of a 53-year-old female with a recurrent WAT. CASE REPORT: The patient presented with abdominal distension, and ultrasound revealed heterogeneous echoes (130 × 93 × 116 mm(3)) around the uterus and ascites. Her cancer antigen 125 (CA125) and CA19-9 levels were elevated. Hysterectomy, bilateral oophorectomy, and tumor resection were performed. The histopathological diagnosis was a WAT...
June 2017: Taiwanese Journal of Obstetrics & Gynecology
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