keyword
MENU ▼
Read by QxMD icon Read
search

Lifestyle Modification

keyword
https://www.readbyqxmd.com/read/29330591/changes-in-the-lipopolysaccharide-of-proteus-mirabilis-9b-m-o11a-clinical-strain-in-response-to-planktonic-or-biofilm-type-of-growth
#1
Agnieszka Zabłotni, Dominik Matusiak, Nikolay P Arbatsky, Magdalena Moryl, Anna Maciejewska, Anna N Kondakova, Alexander S Shashkov, Czesław Ługowski, Yuriy A Knirel, Antoni Różalski
The impact of planktonic and biofilm lifestyles of the clinical isolate Proteus mirabilis 9B-m on its lipopolysaccharide (O-polysaccharide, core region, and lipid A) was evaluated. Proteus mirabilis bacteria are able to form biofilm and lipopolysaccharide is one of the factors involved in the biofilm formation. Lipopolysaccharide was isolated from planktonic and biofilm cells of the investigated strain and analyzed by SDS-PAGE with silver staining, Western blotting and ELISA, as well as NMR and matrix-assisted laser desorption ionization time-of-flight mass spectrometry techniques...
January 12, 2018: Medical Microbiology and Immunology
https://www.readbyqxmd.com/read/29329975/risk-of-suicide-and-non-fatal-self-harm-after-bariatric-surgery-results-from-two-matched-cohort-studies
#2
Martin Neovius, Gustaf Bruze, Peter Jacobson, Kajsa Sjöholm, Kari Johansson, Fredrik Granath, Johan Sundström, Ingmar Näslund, Claude Marcus, Johan Ottosson, Markku Peltonen, Lena M S Carlsson
BACKGROUND: Bariatric surgery reduces mortality, but might have adverse effects on mental health. We assessed the risk of suicide and self-harm after bariatric surgery compared with non-surgical obesity treatment. METHODS: Suicide and non-fatal self-harm events retrieved from nationwide Swedish registers were examined in two cohorts. The non-randomised, prospective Swedish Obese Subjects (SOS) study compared bariatric surgery (n=2010; 1369 vertical-banded gastroplasty, 376 gastric banding, and 265 gastric bypass) with usual care (n=2037; recruitment 1987-2001)...
January 9, 2018: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/29325208/bioinspired-universal-flexible-elastomer-based-microchannels
#3
Feng Wu, Songyue Chen, Baiyi Chen, Miao Wang, Lingli Min, Jack Alvarenga, Jie Ju, Ali Khademhosseini, Yuxing Yao, Yu Shrike Zhang, Joanna Aizenberg, Xu Hou
Flexible and stretchable microscale fluidic devices have a broad range of potential applications, ranging from electronic wearable devices for convenient digital lifestyle to biomedical devices. However, simple ways to achieve stable flexible and stretchable fluidic microchannels with dynamic liquid transport have been challenging because every application for elastomeric microchannels is restricted by their complex fabrication process and limited material selection. Here, a universal strategy for building microfluidic devices that possess exceptionally stable and stretching properties is shown...
January 11, 2018: Small
https://www.readbyqxmd.com/read/29319347/sigma-factors-mediated-signaling-in-mycobacterium-tuberculosis
#4
Peifu Zhou, Xinpeng Wang, Yuzhong Zhao, Wei Yuan, Jianping Xie
Activation of signaling cascades is critical for Mycobacterium tuberculosis (Mtb) to adapt the macrophage lifestyle. Parallel to several signal systems, sigma factor systems, especially the extra-cytoplasmic function sigma factors, are crucial for Mtb signaling. Most sigma factors lack a signal sensory domain and often are activated by various proteins that perceive the environmental cues and relay the signals through variegated post-translational modifications via the activity of antisigma factor, protein kinase and related transcriptional regulators...
January 10, 2018: Future Microbiology
https://www.readbyqxmd.com/read/29318117/risk-factors-for-breast-cancer-among-jordanian-women-a-case-control-study
#5
Mohammad Al Qadire, Murad Alkhalaileh, Hedaya Hina
Background: The interaction between inherited mutated genes and environmental factors is believed to play a crucial role in cancer development. The main aim was to identify lifestyle-related risk factors for breast cancer among Jordanian women. Methods: A hospital-based multicenter case-control study was conducted in Jordan in 2016. Overall, 405 cases and 418 controls, in 3 large hospitals where cancer patients are treated, participated. The prevalence of individual and groups of cancer-related risk factors was estimated descriptively using percentages and odd ratios with their correlated 95% Confidence interval (CI)...
January 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29308941/a-multimodal-physical-therapy-approach-utilizing-the-maitland-concept-in-the-management-of-a-patient-with-cervical-and-lumbar-radiculitis-and-ehlers-danlos-syndrome-hypermobility-type-a-case-report
#6
Adelina Pennetti
The purpose of this case report is to present a multimodal approach for patient management using the Maitland concept framework for cervical and lumbar radiculitis with an underlying diagnosis of Ehlers-Danlos Syndrome-Hypermobility Type (EDS-HT). This case presents care guided by evidence, patient values, and rationale for the selected course of physical therapy treatment provided by therapist experience. A 35-year-old female with a 2-year history of worsening lumbar and cervical pain was referred to physical therapy to address these musculoskeletal issues concurrent with diagnostic testing for EDS...
January 8, 2018: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/29308692/maternal-obesity-diabetes-during-pregnancy-and-epigenetic-mechanisms-that-influence-the-developmental-origins-of-cardiometabolic-disease-in-the-offspring
#7
Prasoon Agarwal, Taylor S Morriseau, Stephanie M Kereliuk, Christine A Doucette, Brandy A Wicklow, Vernon W Dolinsky
Since 1980, global obesity has doubled, and the incidence of cardiometabolic diseases such as type 2 diabetes and heart disease is also increasing. While genetic susceptibility and adult lifestyle are implicated in these trends, evidence from clinical cohorts, epidemiological studies and animal model experiments support a role for early-life environmental exposures in determining the long-term health of an individual, which has led to the formulation of the Developmental Origins of Health and Disease (DOHaD) theory...
January 8, 2018: Critical Reviews in Clinical Laboratory Sciences
https://www.readbyqxmd.com/read/29307987/obese-children-with-fatty-liver-between-reality-and-disease-mongering
#8
REVIEW
Giusy Ranucci, Maria Immacolata Spagnuolo, Raffaele Iorio
Following the current epidemic of obesity, the worldwide prevalence of nonalcoholic fatty liver disease (NAFLD) has increased with potential serious health implications. While it is established that in adults NAFLD can progress to end-stage liver disease in many cases, the risk of progression during childhood is less well defined. Since most obese children are not adherent to lifestyle modifications and hypocaloric diets, there is a growing number of studies on pharmacological interventions with the risk of disease mongering, the practice of widening the boundaries of illness in order to expand the markets for treatment...
December 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29303847/obesity-in-the-workplace-impact-outcomes-and-recommendations
#9
Charles M Yarborough, Stacy Brethauer, Wayne N Burton, Raymond J Fabius, Pamela Hymel, Shanu Kothari, Robert F Kushner, John Magaña Morton, Kathryn Mueller, Nicolaas P Pronk, Mitchell S Roslin, David B Sarwer, Brian Svazas, Jeffrey S Harris, Garrett I Ash, Jamie T Stark, Marianne Dreger, Julie Ording
OBJECTIVE: To conduct a comprehensive literature review to develop recommendations for managing obesity among workers to improve health outcomes and to explore the impact of obesity on health costs to determine whether a case can be made for surgical interventions and insurance coverage. METHODS: We searched PubMed from 2011 to 2016, and CINAHL, Scopus, and Cochrane Registry of Clinical Trials for interventions addressing obesity in the workplace. RESULTS: A total of 1419 articles were screened, resulting in 275 articles being included...
January 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29301630/obesity-pathophysiology-and%C3%A2-management
#10
REVIEW
Kishore M Gadde, Corby K Martin, Hans-Rudolf Berthoud, Steven B Heymsfield
Obesity continues to be among the top health concerns across the globe. Despite our failure to contain the high prevalence of obesity, we now have a better understanding of its pathophysiology, and how excess adiposity leads to type 2 diabetes, hypertension, and cardiovascular disease. Lifestyle modification is recommended as the cornerstone of obesity management, but many patients do not achieve long-lasting benefits due to difficulty with adherence as well as physiological and neurohormonal adaptation of the body in response to weight loss...
January 2, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29300199/recent-advances-in-heart-failure
#11
Mahwash Kassi, Bashar Hannawi, Barry Trachtenberg
PURPOSE OF REVIEW: Acute heart failure continues to be a challenge as there is limited benefit of numerous agents that have been tested. Cardiac resynchronization therapy remains standard of care, yet timing and need for implantable cardiac defibrillator has been brought into question with the recent randomized trials. Several recent advances have been made towards management of heart failure both in drug and device therapy. The purpose of this review is to provide an update on the most important recent studies on heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF)...
January 2, 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29298749/importance-of-active-participation-in-obesity-management-through-mobile-health-care-programs-substudy-of-a-randomized-controlled-trial
#12
Bumjo Oh, Ga-Hye Yi, Min Kyu Han, Jong Seung Kim, Chang Hee Lee, Belong Cho, Hee Cheol Kang
BACKGROUND: Due to the prevalence of the westernized dietary pattern and lack of physical activity, the numbers of overweight or obese individuals are increasing, resulting in a growing health burden because of various related diseases. A lifestyle modification approach has additional advantages compared with pharmacological therapies or bariatric surgery. In our randomized controlled trial conducted in 2015, we successfully used a ubiquitous health care (SmartCare) service for patients with metabolic syndrome to achieve a significant weight loss effect...
January 3, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29297976/platelet-responses-to-pharmacological-and-physiological-interventions-in-middle-aged-men-with-different-habitual-physical-activity-levels
#13
M H Lundberg Slingsby, L Gliemann, M Thrane, N Rytter, J Egelund, M V Chan, P C Armstrong, T D Warner, Y Hellsten
The current guidelines following an acute coronary syndrome recommend dual anti-platelet therapy (aspirin plus a P2Y12 antagonist) alongside lifestyle modifications, including more regular physical activity. It is currently unknown if regular exercise affects the pharmacology of dual anti-platelet therapy. AIM: To explore how exercise-induced improvements in vascular and platelet function affect the efficacy of dual anti-platelet therapy, in a cross-sectional study of men with different physical activity level (training status)...
January 3, 2018: Acta Physiologica
https://www.readbyqxmd.com/read/29297356/should-pregnant-women-be-excluded-from-a-community-based-lifestyle-intervention-trial-a-case-study
#14
Elezebeth Mathews
Kerala, the southernmost Indian state, is known as the diabetes capital of the country. A community-based lifestyle modification program was implemented in the rural areas of Kerala, India, to assess effectiveness in reducing the incidence of type 2 diabetes mellitus (T2DM) among individuals at high risk. High-risk individuals for T2DM were identified through home screening and enrolled into the program after an oral glucose tolerance test to rule out T2DM. Pregnant women were excluded from participation in the trial without justification...
December 14, 2017: Reproductive Health
https://www.readbyqxmd.com/read/29296187/effect-modification-by-region-in-the-associations-of-lep-g2548a-and-lepr-q223r-polymorphisms-with-statin-induced-ck-elevation
#15
Shanqun Jiang, Scott A Venners, Kang Li, Yi-Hsiang Hsu, Justin Weinstock, Yanfeng Zou, Faming Pan, Xiping Xu
We investigated the associations of LEP G2548A and LEPR Q223R polymorphisms with statin-induced creatine kinase (CK) elevation among Chinese patients with hyperlipidemia. A total of587 enrolled individuals were treated with 20 mg/d oral simvastatin for 8 consecutive weeks. Genotyping of LEP G2548A and LEPR Q223R were conducted using PCR-RFLP. Multiple regression analyses showed that, in the Dongzhi region only, patients carrying the LEP AA genotype had a significantly greater increase in CK levels compared to those carrying the AG+GG genotypes after four weeks (P = 0...
December 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/29295697/towards-prevention-of-ovarian-cancer
#16
Aus Tariq Ali
Ovarian cancer is the leading cause of death of all gynaecological cancers. To date, there is no reliable, specific screening procedure for detecting ovarian cancer. The risk factors of ovarian cancer include modifiable and non-modifiable factors. The main goal of the ovarian cancer prevention program is to significantly reduce the risk of development of ovarian cancer and other cancers such as breast and/or peritoneal cancer. The application of non-surgical preventive approaches such as oral contraceptives, parity and breastfeeding has been shown to be highly protective against ovarian cancer development...
January 1, 2018: Current Cancer Drug Targets
https://www.readbyqxmd.com/read/29291422/the-effect-of-multifactorial-lifestyle-interventions-on-cardiovascular-risk-factors-a-systematic-review-and-meta-analysis-of-trials-conducted-in-the-general-population-and-high-risk-groups
#17
REVIEW
L G Sisti, M Dajko, P Campanella, E Shkurti, W Ricciardi, C de Waure
Cardiovascular diseases (CVDs) are the leading cause of premature mortality and disability accounting for one third of all deaths worldwide with considerable impacts on economics and on the quality of life. The evidence suggests that a multifactorial lifestyle intervention might have a role in the CVDs risk reduction, especially in the risk populations, nonetheless the effects on modifiable CVDs risk factors have not been completely explored. Our work aimed at evaluating the impact of multifactorial lifestyle interventions on cardiovascular risk modification, both in the general and risk population...
December 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/29290922/gestational-diabetes-from-a-to-z
#18
REVIEW
AbdelHameed Mirghani Dirar, John Doupis
Gestational diabetes mellitus (GDM) is defined as any degree of hyperglycaemia that is recognized for the first time during pregnancy. This definition includes cases of undiagnosed type 2 diabetes mellitus (T2DM) identified early in pregnancy and true GDM which develops later. GDM constitutes a greater impact on diabetes epidemic as it carries a major risk of developing T2DM to the mother and foetus later in life. In addition, GDM has also been linked with cardiometabolic risk factors such as lipid abnormalities, hypertensive disorders and hyperinsulinemia...
December 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/29287685/medicinal-plants-and-bioactive-natural-compounds-in-the-treatment-of-non-alcoholic-fatty-liver-disease-a-clinical-review
#19
REVIEW
Mohammad Bagherniya, Valerio Nobili, Christopher N Blesso, Amirhossein Sahebkar
Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver diseases, and is closely related to metabolic syndrome and its related conditions, diabetes mellitus and dyslipidemia. On the other hand, NAFLD as a multisystem disease increases the risk of several chronic diseases include type 2 diabetes mellitus, cardiovascular disease (CVD), and chronic kidney disease. The main objective was to review the efficacy of bioactive natural compounds assessed by clinical trials. Search literature using four databases (PubMed, EBSCO, Web of Science, and Ovid Medline) to review publications that focused on the impact of bioactive natural compounds in NAFLD treatment...
December 26, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29285427/physician-perceptions-of-blood-pressure-control-in-patients-with-chronic-kidney-disease-and-target-blood-pressure-achievement-rate
#20
Ran-Hui Cha, Hajeong Lee, Jung Pyo Lee, Young Rim Song, Sung Gyun Kim, Yon Su Kim
Background: Blood pressure (BP) control is the most-established method for the prevention of chronic kidney disease (CKD) progression. However, the ideal BP target for CKD patients is still under debate. Methods: We performed a survey of regular registered members of the Korean Society of Nephrology to determine physician perceptions of BP control in patients with CKD. In addition, we evaluated the target BP achievement rate using data from the APrODiTe-2 study...
December 2017: Kidney Research and Clinical Practice
keyword
keyword
25247
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"