Claire Hopkins, Joaquim Mullol, Asif H Khan, Stella E Lee, Martin Wagenmann, Peter Hellings, Wytske Fokkens, Jérôme Msihid, Radhika Nair, Siddhesh Kamat, Scott Nash, Amr Radwan, Juby A Jacob-Nara, Yamo Deniz, Paul J Rowe
OBJECTIVES: To assess the severity of the top 5 22-item Sino-Nasal Outcome Test (SNOT-22) items ranked most important by patients with chronic rhinosinusitis with nasal polyps (CRSwNP), the effect of dupilumab on these items, and their association with objective disease measures. STUDY DESIGN: Post hoc analysis of the SINUS-24 (NCT02912468) and SINUS-52 (NCT02898454) clinical trials. SETTING: Multinational, multicenter, randomized, double-blind, placebo-controlled, and parallel-group studies...
December 29, 2023: Otolaryngology—Head and Neck Surgery