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https://www.readbyqxmd.com/read/28098589/can-mandibular-condylar-mobility-sonography-measurements-predict-difficult-laryngoscopy
#1
Weidong Yao, Yumei Zhou, Bin Wang, Tao Yu, Zhongbing Shen, Hao Wu, Xiaoju Jin, Yuanhai Li
BACKGROUND: Limited mandibular condylar mobility plays an important role in difficult laryngoscopy. Indirect assessment methods, such as mouth opening, have been proven to be useful predictors of difficult laryngoscopy. Sonography is a new direct assessment method for the limited mandibular condylar mobility. However, whether this method could be used in predicting difficult laryngoscopy still remains unknown. This study aimed to observe its ability to predict difficult laryngoscopy. METHODS: Adult patients who were administered tracheal intubations for elective surgery under general anesthesia were enrolled in the study...
January 16, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28097852/laryngotracheal-edema-due-to-thermal-injury-a-complication-after-thyroidectomy-in-children
#2
Pinar Kendigelen, Ayse C Tutuncu, Gulruh Ashyralyyeva, Senol Emreb, Seval Urkmez, Tughan Utkua, Guner Kaya
Postoperative respiratory insufficiency is a serious complication of total thyroidectomies which can be multifactorial, especially in children. We report two siblings who had undergone thyroidectomy with subsequent respiratory distress. Electrothermal bipolar and harmonic scalpel were used during thyroid dissections. Both patients had early postoperative respiratory problems. The older one suffered from mild respiratory distress for 24 hours and then he spontaneously recovered. The younger one was extubated but then she had serious stridor accompanied with abdominal and intercostal retractions...
February 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28097001/mag-dpa-curbs-inflammatory-biomarkers-and-pharmacological-reactivity-in-cytokine-triggered-hyperresponsive-airway-models
#3
Rayan Khaddaj-Mallat, Roddy Hiram, Chantal Sirois, Marco Sirois, Edmond Rizcallah, Sofia Marouan, Caroline Morin, Éric Rousseau
Bronchial inflammation contributes to a sustained elevation of airway hyperresponsiveness (AHR) in asthma. Conversely, omega-3 fatty acid derivatives have been shown to resolve inflammation in various tissues. Thus, the effects of docosapentaenoic acid monoacylglyceride (MAG-DPA) were assessed on inflammatory markers and reactivity of human distal bronchi as well as in a cultured model of guinea pig tracheal rings. Human bronchi were dissected and cultured for 48 h with 10 ng/mL TNF-α or IL-13. Guinea pig tracheas were maintained in organ culture for 72 h which was previously shown to trigger spontaneous AHR...
December 2016: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/28096867/nasal-nosocomial-myiasis-infection-caused-by-chrysomya-bezziana-diptera-calliphoridae-following-the-septicemia-a-case-report
#4
Seyed Farzin Mircheraghi, Seyed Farzam Mircheraghi, Hamed Ramezani Awal Riabi, Arezoo Parsapour
A 74 yr old woman from Gonabad, southern part of Khorasan Razavi Province of Iran was admitted to a Hospital of Gonabad, because of respiratory distress, exertional dyspnea and fever. Close contact with domestic animals, history of chronic obstructive pulmonary disease (COPD), and completely resolved pulmonary tuberculosis (TB) in remote past, were notable parts of her past medical history. Due to clinical, paraclinical and radiographic findings and because of recent hospitalization, she was admitted to internal medicine ward with the diagnosis of health care associated pneumonia (HCAP)...
April 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28096586/comparison-of-intubating-laryngeal-mask-airway-and-fiberoptic-bronchoscopy-for-endotracheal-intubation-in-patients-undergoing-cervical-discectomy
#5
Kolli S Chalam, Jyothi Gupta
BACKGROUND AND AIMS: Direct laryngoscopy is hazardous in patients with cervical posterior intervertebral disc prolapse (PIVD) as it may worsen the existing cord compression. To achieve smooth intubation, many adjuncts such as fiberoptic bronchoscope (FOB), video laryngoscopes, lighted stylets, and intubating laryngeal mask airways (ILMAs) are available. However, there is a paucity of literature comparing ILMA with fiberoptic intubation in patients with PIVD. Hence, this study was designed to compare the effectiveness of ILMA technique with FOB to accomplish endotracheal intubation in patients undergoing cervical discectomy...
October 2016: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/28094479/retromolar-laryngoscopy-a-randomised-cross-over-vocal-cords-visualisation-study
#6
Christian Reiterer, Barbara Waltl, Barbara Kabon, Wolfgang Schramm
BACKGROUND: Vocal cords visualisation is a major determinant for successful tracheal intubation. The aim of our study was to compare vocal cord visualisation by using conventional direct laryngoscopy with retromolar direct laryngoscopy in patients with an existing retromolar gap at the right mandible. METHODS: We enrolled 100 adults needing endotracheal intubation for elective surgery. In each patient the vocal cords were visualised and scored according to Cormack & Lehane with a Macintosh blade #3 for conventional technique and with a Miller blade #4 for the retromolar technique in a randomised sequence...
January 17, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28094453/down-regulation-of-a-chitin-synthase-a-gene-by-rna-interference-enhances-pathogenicity-of-beauveria-bassiana-anu1-against-spodoptera-exigua-h%C3%A3-bner
#7
Jung-Bok Lee, Hyun Soo Kim, Youngjin Park
Chitin synthase (CHS) is an important enzymatic component, which is required for chitin formation in the cuticles and cuticular linings of other tissues in insects. CHSs have been divided into two classes, classes A and B, based on their amino acid sequence similarities and functions. Class A CHS (CHS-A) is specifically expressed in the epidermis and related ectodermal cells such as tracheal cells, while class B CHS (CHS-B) is expressed in gut epithelial cells that produce peritrophic matrices. In this study, we cloned the CHS-A gene from the beet armyworm, Spodoptera exigua (SeCHS-A)...
January 17, 2017: Archives of Insect Biochemistry and Physiology
https://www.readbyqxmd.com/read/28093725/shape-and-geometry-control-of-the-drosophila-tracheal-tubule
#8
REVIEW
Shigeo Hayashi, Bo Dong
For efficient respiration, tubular airways must be constructed with an optimal diameter and length for the dimensions of the body. In Drosophila, the growth of embryonic tracheal tubules proceeds in two dimensions, by axial elongation and diameter expansion. The growth forces in each dimension are controlled by distinct genetic programs and cellular mechanisms. Recent studies reveal that the apical cortex and the apical extracellular matrix filling the luminal space are essential for the generation, balancing, and equilibrium of these growth forces...
January 17, 2017: Development, Growth & Differentiation
https://www.readbyqxmd.com/read/28089425/-a-comparison-of-various-supraglottic-airway-devices-for-fiberoptical-guided-tracheal-intubation
#9
Thomas Metterlein, Anna Dintenfelder, Christoph Plank, Bernhard Graf, Gabriel Roth
BACKGROUND: Fiberoptical assisted intubation via placed supraglottic airway devices has been described as safe and easy procedure to manage difficult airways. However visualization of the glottis aperture is essential for fiberoptical assisted intubation. Various different supraglottic airway devices are commercially available and might offer different conditions for fiberoptical assisted intubation. The aim of this study was to compare the best obtainable view of the glottic aperture using different supraglottic airway devices...
January 12, 2017: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28088789/gprc5a-knockout-mouse-lung-epithelial-cells-predicts-ceruloplasmin-lipocalin-2-and-periostin-as-potential-biomarkers-at-early-stages-of-lung-tumorigenesis
#10
Beibei Sun, Wenzheng Guo, Song Hu, Feng Yao, Keke Yu, Jie Xing, Ronghua Wang, Hongyong Song, Yueling Liao, Tong Wang, Pengfei Jiang, Baohui Han, Jiong Deng
Lung cancer is the leading cause of cancer death. As most of lung cancer patients were diagnosed with the advanced stage, early detection is considered as the most effective strategy to reduce high mortality. Thus, it is desirable to identify specific biomarkers at early stages of lung tumorigenesis. GPRC5A is a lung tumor suppressor gene. GPRC5A deficiency is linked to lung cancer development. We hyposthesized that, dysregulated gene expression that results from Gprc5a deficiency may provide potential biomarkers at early stages of lung tumorigenesis...
January 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/28088518/s100a8-protein-attenuates-airway-hyperresponsiveness-by-suppressing-the-contraction-of-airway-smooth-muscle
#11
Yu-Dong Xu, Yu Wang, Lei-Miao Yin, Gyoung-Hee Park, Luis Ulloa, Yong-Qing Yang
Airway hyperresponsiveness (AHR) is a major clinical problem in allergic asthma mainly caused by the hypercontractility of airway smooth muscles (ASM). S100A8 is an important member of the S100 calcium-binding protein family with a potential to regulate cell contractility. Here, we analyze the potential of S100A8 to regulate allergen-induced AHR and ASM contraction. Treatment with recombinant S100A8 (rS100A8) diminished airway hyperresponsiveness in OVA-sensitized rats. ASM contraction assays showed that rS100A8 reduced hypercontractility in both isolated tracheal rings and primary ASM cells treated by acetylcholine...
January 11, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28088174/feasibility-and-safety-of-dilatational-tracheotomy-using-the-rigid-endoscope-a-multicenter-study
#12
Andreas Nowak, Peter Kern, Sven Koscielny, Taras I Usichenko, Klaus Hahnenkamp, Markus Jungehülsing, Matthias Tittel, Jens Oeken, Eckart Klemm
BACKGROUND: Fiberoptic tracheo-bronchoscopy is the most commonly used procedure for percutaneous dilational tracheotomy (PDT). However, PDT can be associated with major complications, including death. Furthermore it is unclear, whether the tracheal ring fractures may contribute to the development of tracheal stenosis after PDT nor whether tracheal ring fractures can be prevented by using a rigid endoscope for this procedure. The purpose of this study was to evaluate the feasibility of and the incidence of complications for PDT using the rigid tracheotomy endoscope (TED)...
January 14, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28087625/faithful-mrna-splicing-depends-on-the-prp19-complex-subunit-faint-sausage-and-is-required-for-tracheal-branching-morphogenesis-in-drosophila
#13
Julia Sauerwald, Charlotte Soneson, Mark D Robinson, Stefan Luschnig
Morphogenesis requires the dynamic regulation of gene expression, including transcription, mRNA maturation and translation. Dysfunction of the general mRNA splicing machinery can cause surprisingly specific cellular phenotypes, but the basis for these effects is not clear. Here we show that the Drosophila faint sausage (fas) locus, implicated in epithelial morphogenesis and previously reported to encode a secreted immunoglobulin domain protein, in fact encodes a subunit of the spliceosome-activating Prp19 complex, which is essential for efficient pre-mRNA splicing...
January 13, 2017: Development
https://www.readbyqxmd.com/read/28081306/tracheal-intubation-in-patients-immobilized-by-a-rigid-collar-a-comparison-of-glidescope-and-an-intubating-laryngeal-mask-airway
#14
Semih Özdil, Zehra İpek Arslan Aydın, Zehra Nur Baykara, Kamil Toker, Zeynep Mine Solak
BACKGROUND/AIM: Intubation must be rapidly performed with the utmost care in cervical trauma patients. We present the first comparison of GlideScope and an intubating laryngeal mask airway (ILMA) regarding insertion and intubation times, intubation success rates, mucosal damage, need for optimization maneuvers, effects on hemodynamic changes, and postoperative minor complications in a simulated cervical injury with a Philadelphia cervical collar. MATERIALS AND METHODS: Ethics committee approval and patient consent were obtained and 94 American Society of Anesthesiology physical status I or II patients were enrolled in this study...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28081255/changes-in-dna-methylation-in-mouse-lungs-after-a-single-intra-tracheal-administration-of-nanomaterials
#15
Ali M Tabish, Katrien Poels, Hyang-Min Byun, Katrien Luyts, Andrea A Baccarelli, Johan Martens, Stef Kerkhofs, Sven Seys, Peter Hoet, Lode Godderis
AIMS: This study aimed to investigate the effects of nanomaterial (NM) exposure on DNA methylation. METHODS AND RESULTS: Intra-tracheal administration of NM: gold nanoparticles (AuNPs) of 5-, 60- and 250-nm diameter; single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) at high dose of 2.5 mg/kg and low dose of 0.25 mg/kg for 48 h to BALB/c mice. Study showed deregulations in immune pathways in NM-induced toxicity in vivo. NM administration had the following DNA methylation effects: AuNP 60 nm induced CpG hypermethylation in Atm, Cdk and Gsr genes and hypomethylation in Gpx; Gsr and Trp53 showed changes in methylation between low- and high-dose AuNP, 60 and 250 nm respectively, and AuNP had size effects on methylation for Trp53...
2017: PloS One
https://www.readbyqxmd.com/read/28078354/-tracheal-laceration-after-dilatational-tracheostomy-a-case-of-succesful-conservative-management
#16
L Eichler, M Simon, S Kluge
During bronchoscopically guided percutaneous dilatational tracheostomy, a 71-year-old woman suffered a long-stretched tear to the posterior tracheal wall. The injury was suspected to be caused by blunt trauma during dilation or cannula insertion, possibly aggravated by vigorous cuff inflation. Since the defect ended just 0.5 cm proximal to the main carina, placing a cuffed endotracheal tube beyond the injury was not an option. However, we decided for a conservative treatment approach by placing a cuffed endotracheal tube under bronchoscopic visualization in direct proximity to the cranial end of the laceration...
January 11, 2017: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/28077525/oxygen-supplementation-during-prolonged-tracheal-intubation-should-be-the-standard-of-care
#17
EDITORIAL
J E Fiadjoe, R S Litman
No abstract text is available yet for this article.
October 2016: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28077185/rapidly-progressive-mitral-valve-stenosis-in-patients-with-acromelic-dysplasia
#18
Gabriel Rama, Wendy K Chung, Christopher M Cunniff, Usha Krishnan
Acromelic dysplasias are a group of skeletal dysplasias characterised by short-limbed short stature with other distinctive phenotypic features including small hands and feet and stiff joints. Geleophysic dysplasia is an acromelic dysplasia that is associated with characteristic facial features, progressive cardiac valvular thickening, and tracheal stenosis. Owing to overlapping clinical features with other types of short-limbed skeletal dysplasias, it is important to make a precise diagnosis as they have different cardiac morbidity and mortality...
January 12, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28076961/total-arch-replacement-through-a-median-sternotomy-for-kommerell-s-diverticulum
#19
Yoshihiro Goto, Yutaka Koyama, Soh Hosoba, Shinji Ogawa, Shunsuke Fukaya, Yasuhide Okawa
Kommerell's diverticulum with a right aortic arch and aberrant left subclavian artery is a rare anomaly, and the optimal operative strategy has not yet been established. In particular, the approach to the diverticulum is controversial, with the greatest concern being whether or not to add a right thoracotomy to the median sternotomy for distal anastomosis. We successfully performed total arch replacement through a median sternotomy only, by referring to preoperative computed tomography. We think that if the aneurysm is in a shallow position from the tracheal bifurcation, total arch replacement is possible with a midline incision only...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28074826/extracorporeal-membrane-oxygenation-for-repair-of-tracheal-injury-during-transhiatal-esophagectomy
#20
Lilibeth Fermin, Sarah Arnold, Lorena Nunez, Danny Yakoub
Extracorporeal Membrane Oxygenation (ECMO) for repair of tracheal injury during transhiatal esophagectomy Tracheal injury is a rare but potentially fatal complication of esophagectomies requiring prompt recognition and treatment. We describe a case of tracheal injury recognized in the operative period of an open transhiatal esophagectomy for squamous cell carcinoma of the mid to distal esophagus. When injury was discovered, attempts to improve oxygenation and ventilation by conventional methods were unsuccessful...
January 2017: Annals of Cardiac Anaesthesia
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