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https://www.readbyqxmd.com/read/28741217/effects-of-non-invasive-ventilation-in-patients-with-acute-respiratory-failure-excluding-post-extubation-respiratory-failure-cardiogenic-pulmonary-edema-and-exacerbation-of-copd-a-systematic-review-and-meta-analysis
#1
Yutaka Kondo, Junji Kumasawa, Atsushi Kawaguchi, Ryutaro Seo, Eishu Nango, Satoru Hashimoto
BACKGROUND: This meta-analysis compared the effects of non-invasive ventilation (NIV) with invasive mechanical ventilation (InMV) and standard oxygen (O2) therapy on mortality and rate of tracheal intubation in patients presenting acute respiratory failure (ARF). METHODS: We searched the MEDLINE, EMBASE and Cochrane Central Register of clinical trials databases between 1949 and May 2015 to identify randomized trials of NIV for ARF. We excluded the ARF caused by extubation, cardiogenic pulmonary edema, and COPD...
July 24, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/28740393/current-evidence-for-the-use-of-c-mac-videolaryngoscope-in-adult-airway-management-a-review-of-the-literature
#2
REVIEW
Fu-Shan Xue, Hui-Xian Li, Ya-Yang Liu, Gui-Zhen Yang
The C-MAC videolaryngoscope is the first Macintosh-typed videolaryngoscope. Since the advent of its original version video Macintosh system in 1999, this device has been modified several times. A unique feature of C-MAC device is its ability to provide the 2 options of direct and video laryngoscopy with the same device. The available evidence shows that in patients with normal airways, C-MAC videolaryngoscope compared with direct laryngoscopy can provide comparable or better laryngeal views and exerts less force on maxillary incisors, but does not offer conclusive benefits with regard to intubation time, intubation success, number of intubation attempts, the use of adjuncts, and hemodynamic responses to intubation...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28739827/transcriptional-profiling-of-the-chicken-tracheal-response-to-virulent-mycoplasma-gallisepticum-strain-rlow
#3
J Beaudet, E R Tulman, K Pflaum, X Liao, G F Kutish, S M Szczepanek, L K Silbart, S J Geary
Mycoplasma gallisepticum, the primary etiologic agent of Chronic Respiratory Disease (CRD) in poultry, leads to prolonged recruitment and activation of inflammatory cells in the respiratory mucosa. This is consistent with the current model of immune dysregulation that ostensibly allows the organism to evade clearance mechanisms and establish chronic infection. To date, studies using qRT-PCR and microarrays have shown a significant transient up-regulation of cytokines and chemokines from tracheal epithelial cells (TECs) in vitro and tracheal tissue ex vivo in response to virulent strain Rlow, that contributes to the infiltration of inflammatory cells into the tracheal mucosa...
July 24, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/28739545/an-optimized-non-destructive-protocol-for-testing-mechanical-properties-in-decellularized-rabbit-trachea
#4
M Den Hondt, B M Vanaudenaerde, E F Maughan, C R Butler, C Crowley, E K Verbeken, S E Verleden, J J Vranckx
Successful tissue-engineered tracheal transplantation relies on the use of non-immunogenic constructs, which can vascularize rapidly, support epithelial growth, and retain mechanical properties to that of native trachea. Current strategies to assess mechanical properties fail to evaluate the trachea to its physiological limits, and lead to irreversible destruction of the construct. Our aim was to develop and evaluate a novel non-destructive method for biomechanical testing of tracheae in a rabbit decellularization model...
July 21, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28739281/ventilation-rate-in-adults-with-a-tracheal-tube-during-cardiopulmonary-resuscitation-a-systematic-review
#5
REVIEW
Gino Vissers, Jasmeet Soar, Koenraad G Monsieurs
The optimal ventilation rate during cardiopulmonary resuscitation (CPR) with a tracheal tube is unknown. We evaluated whether in adults with cardiac arrest and a secure airway (tracheal tube), a ventilation rate of 10min(-1), compared to any other rate during CPR, improves outcomes.
July 21, 2017: Resuscitation
https://www.readbyqxmd.com/read/28738337/the-history-of-sleep-surgery
#6
Kathleen Yaremchuk, Laura Garcia-Rodriguez
Snoring and the subsequent diagnosis of obstructive sleep apnea (OSA) was a life-threatening medical condition with no available treatment until the late 20th century. An early description of OSA was provided by Charles Dickens in his 1836 novel Pickwick Papers with the description of a "fat boy" who was thought to be lazy and always falling asleep but likely displayed hypersomnolence from OSA. It was not until 1976 that Ikematsu first described uvulopalatopharyngoplasty (UPPP) as an alternative surgical treatment of "snoring," with a reported cure rate of 81%...
2017: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28737223/a-network-meta-analysis-of-the-clinical-properties-of-various-types-of-supraglottic-airway-device-in-children
#7
REVIEW
T Mihara, A Asakura, G Owada, A Yokoi, K Ka, T Goto
We conducted both conventional pairwise and Bayesian network meta-analyses to compare the clinical properties of supraglottic airway devices in children. We searched six databases for randomised clinical trials. Our primary end-points were oropharyngeal leak pressure, risk of insertion failure at first attempt, and blood staining risk. The risk of device failure, defined as the abandonment of the supraglottic airway device and replacement with a tracheal tube or another device, was also analysed. Sixty-five randomised clinical trials with 5823 participants were identified, involving 16 types of supraglottic airway device...
July 24, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28736614/tracheal-granuloma-7-years-after-extubation
#8
Kazuhisa Nakashima, Tateaki Naito, Masahiro Endo, Takashi Nakajima, Toshiaki Takahashi
Tracheal granuloma can cause severe stenosis long after extubation. When a patient with a history of endobronchial intubation has an intratracheal tumour, we should consider the possibility of this condition.
September 2017: Respirology Case Reports
https://www.readbyqxmd.com/read/28734807/-a-survey-on-premedication-prior-to-intubation-in-very-preterm-infants-28-32wg-with-respiratory-distress-syndrome-in-french-neonatal-intensive-care-units
#9
E Boiron, E Merlot, G Loron, X Durrmeyer, E Guyot
INTRODUCTION/OBJECTIVES: Tracheal intubation is a painful procedure for which the routine use of analgesia is recommended. However, the use of premedication for intubation is not yet generalized and there is great diversity in the drugs used. The main objective of this study was to describe the frequency of premedication use in preterm neonates aged between 28 and 32weeks of gestation, intubated for respiratory distress syndrome. Secondary objectives were to describe the existence of a written protocol, its influence on the frequency of premedication and the drugs used...
July 19, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28734446/successful-lung-transplantation-using-a-deceased-donor-mechanically-ventilated-for-ten-months
#10
Shin Tanaka, Kentaroh Miyoshi, Seiichiro Sugimoto, Masaomi Yamane, Motomu Kobayashi, Takahiro Oto
A successful outcome after lung transplant was achieved using lungs donated from a teenage boy who underwent prolonged mechanical ventilation. The donor experienced hypoxic brain damage and was declared brain dead 324 days after tracheal intubation. At the time of referral, the donor's lungs revealed diffuse radiologic infiltration and atelectasis but excellent function, with a PaO2/FiO2 ratio of 450. The lungs were transplanted to a 10-year-old girl with bronchiolitis obliterans. She developed grade 2 primary graft dysfunction, but recovered quickly...
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28734442/nonintubated-spontaneous-respiration-anesthesia-for-tracheal-glomus-tumor
#11
Jun Huang, Yuan Qiu, Lei Chen, Hui Liu, Qinglong Dong, Lixia Liang, Jiaxi He, Jianxing He, Hanzhang Chen
Previous tracheal surgeries were performed under tracheal and cross-field intubation. However, the intubation would lead to bleeding if the tumors were large or hemorrhagic. Moreover, the tracheal intubation might interfere the surgical vision and anastomosis during the reconstruction process. Therefore, we performed a tracheal tumor resection and reconstruction via nonintubated spontaneous anesthesia. We describe the feasibility and safety of tracheal surgeries via such anesthesia.
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28734029/successful-treatment-of-metastatic-clear-cell-carcinoma-with-nivolumab-in-a-patient-receiving-dialysis-treatment
#12
Tadashi Tabei, Ichiro Natsume, Kazuki Kobayashi
The efficacy and safety of nivolumab for patients receiving dialysis treatment has not been established yet. Herein, we describe a patient on dialysis successfully treated with nivolumab as seventh-line therapy for metastatic renal cell carcinoma. Before initiating nivolumab, he had respiratory discomfort induced by a lesion occluding the left intermediate bronchus that originated from the metastatic lymph node behind the tracheal bifurcation. Four weeks after nivolumab was initiated, his symptom remarkably improved, and the occlusion disappeared according to the bronchoscopy examination...
July 21, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28731623/concentric-photothermal-coagulation-with-basket-integrated-optical-device-for-treatment-of-tracheal-stenosis
#13
Van Nam Tran, Hyungshin Lee, Van Gia Truong, Yun-Hee Rhee, Hyun Wook Kang
A basket-integrated optical device is developed to consistently treat tubular tissue by centering an optical diffuser in the lumen. Four nitinol arms in conjunction with the optical diffusing applicator are deployed to induce homogeneous circumferential light emission and concentric photothermal coagulation on tracheal tissue. 1470-nm laser light is employed for the tissue testing at various irradiation conditions and evaluated in terms of thermal gradient and temperature evolution. Preliminary experiments on liver tissue demonstrate the concentric development of the radial thermal coagulation in the tissue (eccentric ratio = ~5...
July 21, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28730932/effect-site-concentration-of-remifentanil-required-to-blunt-haemodynamic-responses-during-tracheal-intubation-a-randomized-comparison-between-single-and-double-lumen-tubes
#14
Tae Kyong Kim, Deok Man Hong, Seo Hee Lee, Hyesun Paik, Se Hee Min, Jeong-Hwa Seo, Chul-Woo Jung, Jae-Hyon Bahk
Objective To investigate the effect-site concentration of remifentanil required to blunt haemodynamic responses during tracheal intubation with a single-lumen tube (SLT) or a double-lumen tube (DLT). Methods Patients scheduled for thoracic surgery requiring one-lung ventilation were randomly allocated to either the SLT or DLT group. All patients received a target-controlled infusion of propofol and a predetermined concentration of remifentanil. Haemodynamic parameters during intubation were recorded. The effect-site concentration of remifentanil was determined using a delayed up-and-down sequential allocation method...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28730534/tracheal-cartilage-isolation-and-decellularization
#15
Zachary Galliger, Angela Panoskaltsis-Mortari
Tissue decellularization allows isolation of tissue extracellular matrix components, enabling bioengineering of native tissue microenvironments with minimal antigenic components. Here we describe a method to harvest decellularized cartilage tissue from donor trachea using a series of chemical and enzymatic washes and incorporating the extracellular matrix in gelatin methacrylate hydrogels. This decellularized cartilage tissue is easily incorporated into a variety of hydrogels to create a cartilage tissue scaffold...
July 21, 2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28730380/acute-and-chronic-effects-of-oral-erdosteine-on-ciliary-beat-frequency-cough-sensitivity-and-airway-reactivity
#16
L Pappová, I Kazimierová, M Jošková, M Šutovská, S Fraňová
Erdosteine as a mucolytic agent that decreases mucus viscosity and facilitates mucus expulsion from the airways by cough or ciliary movement. Our objective was to determine whether erdosteine can directly contribute to mucus clearance. We addressed the issue by monitoring acute and chronic effects of erdosteine on ciliary beat frequency (CBF), cough sensitivity, and airway smooth muscle reactivity. The experiments were performed in healthy guinea pigs. Erdosteine (10 mg/kg) was administrated orally in a single dose or daily through 7 days...
July 21, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28729279/complete-genome-sequence-of-an-avian-metapneumovirus-subtype-a-strain-isolated-from-chicken-gallus-gallus-in-brazil
#17
Laís S Rizotto, Guilherme P Scagion, Tereza C Cardoso, Raphael M Simão, Leonardo C Caserta, Julia C Benassi, Lara B Keid, Trícia M F de S Oliveira, Rodrigo M Soares, Clarice W Arns, Steven Van Borm, Helena L Ferreira
We report here the complete genome sequence of an avian metapneumovirus (aMPV) isolated from a tracheal tissue sample of a commercial layer flock. The complete genome sequence of aMPV-A/chicken/Brazil-SP/669/2003 was obtained using MiSeq (Illumina, Inc.) sequencing. Phylogenetic analysis of the complete genome classified the isolate as avian metapneumovirus subtype A.
July 20, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28727703/intrathecal-morphine-improves-hemodynamic-parameters-and-analgesia-in-patients-undergoing-aortic-valve-replacement-surgery-a-prospective-double-blind-randomized-trial
#18
Hamed Elgendy, Hatem A R Helmy
BACKGROUND: Intrathecal morphine (ITM) has been used in hopes of providing good postoperative analgesia in cardiac surgery. Little is known about its use in isolated aortic valve replacement surgery. OBJECTIVES: To evaluate the effects of 7 µ/kg ITM administration in aortic valve replacement in regards to hemodynamics, pain score, and postoperative complications when compared to general anesthesia alone. STUDY DESIGN: A randomized, double-blind trial...
July 2017: Pain Physician
https://www.readbyqxmd.com/read/28727542/single-session-high-intensity-focused-ultrasound-treatment-for-persistent-or-relapsed-graves-disease-preliminary-experience-in-a-prospective-study
#19
Brian Hung-Hin Lang, Yu-Cho Woo, Ian Yat-Hin Wong, Keith Wan-Hang Chiu
Purpose To evaluate the safety and efficacy of ultrasonography (US)-guided high-intensity focused ultrasound (HIFU) ablation as a treatment for medically refractory Graves disease (GD). Materials and Methods After ethics approval, a prospective trial (NCT02685514) was performed from November 2015 to February 2016. Thirty patients underwent ablation of the entire right and left thyroid lobes, with areas near the tracheal-esophageal groove and common carotid artery left unablated. Serum thyroid-stimulating hormone (TSH), free T4 (FT4), antithyroid autoantibodies, and TSH receptor (TSHR) antibody levels were evaluated afterward, and US color Doppler, US volumetry, and eye assessment were performed...
July 20, 2017: Radiology
https://www.readbyqxmd.com/read/28723308/percutaneous-trans-tracheal-endoscopic-approach-a-novel-technique-for-the-excision-of-benign-lesions-of-thoracic-trachea
#20
Suresh C Sharma, K Devaraja, Arvind Kairo, Rakesh Kumar
INTRODUCTION: Currently, neoplasms of the trachea and lower airway demand open transcervical approach with or without thoracotomy. We describe here a novel, minimally invasive approach for an intraluminal lesion of the thoracic trachea, called percutaneous trans-tracheal endoscopic approach (PTEA). Apart from obvious advantages over potentially morbid open procedures, this technique has certain peculiar benefits over rigid or flexible bronchoscopic approach. MATERIALS AND METHODS: A 43-year-old male patient had glomus tumor of thoracic trachea...
July 19, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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