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Fetal ductus venosus

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https://www.readbyqxmd.com/read/27854388/prediction-of-stillbirth-from-placental-growth-factor-at-11-13-weeks
#1
R Akolekar, M Machuca, M Mendes, V Paschos, K H Nicolaides
OBJECTIVES: To investigate whether the addition of maternal serum placental growth factor (PlGF) measured at 11-13 weeks' gestation improves the performance of screening for stillbirths that is achieved by a combination of maternal factors and first-trimester biomarkers such as maternal serum pregnancy-associated plasma protein-A (PAPP-A), fetal ductus venosus pulsatility index for veins (DV-PIV) and uterine artery pulsatility index (UtA-PI) and to evaluate the performance of screening with this model for all stillbirths and those due to impaired placentation and unexplained causes...
November 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27854382/the-truffle-study-fetal-monitoring-indications-for-delivery-in-310-iugr-infants-with-2-year-s-outcome-delivered-before-32-weeks-of-gestation
#2
Gerard H A Visser, C M Bilardo, J B Derks, E Ferrazzi, N Fratelli, T Frusca, W Ganzevoort, C Lees, R Napolitano, T Todros, H Wolf, K Hecher, N Marlow, B Arabin, C Brezinka, A Diemert, J J Duvekot, P Martinelli, E Ostermayer, A T Papageorghiou, D Schlembach, Ktm Schneider, B Thilaganathan, A Valcamonico
OBJECTIVE: In the TRUFFLE study on outcome of early fetal growth restriction women were allocated to three timing of delivery plans according to antenatal monitoring strategies based on reduced computerized cardiotocographic heart rate short term variation (c-CTG STV) , early Ductus Venosus (DV p95) or late DV (DV noA) changes. However, many infants were per protocol delivered because of 'safety net' criteria, or for maternal indications, or 'other fetal indications' or after 32 weeks of gestation when the protocol was not applied anymore...
November 11, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27813120/prediction-of-neonatal-outcome-of-ttts-by-fetal-heart-and-doppler-ultrasound-parameters-before-and-after-laser-treatment
#3
A Delabaere, F Leduc, Q Reboul, F Fuchs, S Wavrant, J C Fouron, F Audibert
OBJECTIVES: To determine the prognostic value of fetal Doppler and echocardiographic parameters for neonatal survival up to 30 days after laser coagulation in monochorionic pregnancies complicated by twin-twin transfusion syndrome (TTTS). METHODS: Fetal echocardiography and outcome data of consecutive cases of TTTS treated by laser were retrospectively reviewed. Hemodynamic and cardiac function parameters were collected before and after laser. RESULTS: Between February 2006 and January 2015, 106 fetoscopic laser were performed...
November 3, 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27757222/in-utero-origin-of-sex-related-differences-in-future-cardiovascular-disease
#4
Sarah Schalekamp-Timmermans, Jerome Cornette, Albert Hofman, Willem A Helbing, Vincent W V Jaddoe, Eric A P Steegers, Bero O Verburg
BACKGROUND: There are sex differences in the risk of development of cardiovascular disease (CVD). According to the developmental origins of health and disease paradigm (DOHaD), CVD originates in fetal life. This study examines fetal sex differences in cardiovascular development in utero. METHODS: In 1028 pregnant women, we assessed fetal circulation using pulsed wave Doppler examinations between 28 and 34 weeks gestation. To test associations between fetal sex and fetal circulation measurements, linear regression models were used adjusting for fetal size, gestational age, and fetal heart rate...
2016: Biology of Sex Differences
https://www.readbyqxmd.com/read/27684831/length-to-width-ratio-of-the-ductus-venosus-in-simple-screening-for-fetal-congenital-heart-diseases-in-the-second-trimester
#5
Wei-Hsiu Chiu, Shy-Ming Lee, Tao-Hsin Tung, Xiao-Mei Tang, Ren-Shyan Liu, Ran-Chou Chen
Antenatal diagnosis of congenital heart disease (CHD) is still low even though screening was first introduced over 25 years ago. The purpose of our study was to determine the efficacy of a second-trimester prenatal ultrasonographic method of screening for CHD.From September 2012 to September 2013, the length and width of the fetal ductus venosus were measured sonographically in 1006 singleton fetuses, and the ratio of length to width was calculated. The accuracy of each fetal measurement and Doppler ultrasonography were determined...
September 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27561595/prediction-of-stillbirth-from-biochemical-and-biophysical-markers-at-11-13-weeks
#6
S Mastrodima, R Akolekar, G Yerlikaya, T Tzelepis, K H Nicolaides
OBJECTIVES: To develop a model for the prediction of stillbirth that is based on a combination of maternal characteristics and medical history with first-trimester biochemical and biophysical markers and to evaluate the performance of screening with this model for all stillbirths and those due to impaired placentation and unexplained causes. METHODS: This was a prospective screening study of 76 897 singleton pregnancies, including 76 629 live births and 268 (0.35%) antepartum stillbirths; 157 (59%) were secondary to impaired placentation and 111 (41%) were due to other or unexplained causes...
November 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27512094/numerical-investigation-of-the-hemodynamics-in-the-fetal-umbilical-vein-ductus-venosus-based-on-%C3%A2-experimental-data
#7
Taraneh Rezaee, Kamran Hassani
Abortion of the fetus due to a disease has been dramatically increased in the last decades. There is a still lack of knowledge on the various types of diseases which lead fetus to a vulnerable circumstance. The transport of oxygenated blood from the placenta to the human fetus has been an important clinical feature in Doppler velocimetry studies, especially the Ductus Venosus (DV). The DV connects intra-abdominal portion of the umbilical vein and the Inferior Vena Cava (IVC) at the inlet of the right atrium and is, therefore, important when examining the fetus state of health...
August 10, 2016: Bioscience Reports
https://www.readbyqxmd.com/read/27505083/hematological-changes-in-severe-early-onset-growth-restricted-fetuses-with-absent-and-reversed-end-diastolic-flow-in-the-umbilical-artery
#8
Franz Bahlmann, Ammar Al Naimi, Manfred Ossendorf, Monica Schmidt-Fittschen, Arne Willruth
BACKGROUND: Erythropoietin seems to play an important role in the regulation of fetal hypoxemia. The present prospective study was designed to determine if changes in erythropoietin levels can be found in fetuses with severe early-onset growth restriction and hemodynamic compromise. METHODS AND RESULTS: Erythropoietin, hemoglobin, hematocrit, platelet counts, normoblasts, lacate, arterial and venous blood gasses in the umbilical cord were determined in 42 fetuses with fetal growth restriction (IUGR) with absent (zero-flow) and 26 IUGR fetuses with retrograde end-diastolic flow (reverse-flow) in the umbilical artery...
August 9, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27491505/what-are-the-most-common-first-trimester-ultrasound-findings-in-cases-of-turner-syndrome
#9
Marcin Wiechec, Anna Knafel, Agnieszka Nocun, Ewa Wiercinska, Artur Ludwin, Inga Ludwin
OBJECTIVES: To identify the most common first-trimester ultrasound findings in Turner syndrome (TS). To evaluate which first-trimester findings can be best used to predict the likelihood of TS. METHODS: This was a prospective study, based on singleton pregnancies. The referrals included 6210 patients. Scan protocol covered a review of the early fetal anatomy and markers of aneuploidy. RESULTS: Study population comprised 5644 pregnancies: 5613 with a normal karyotype and 31 cases of TS...
August 29, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27484356/a-longitudinal-study-of-computerised-cardiotocography-in-early-fetal-growth-restriction
#10
Hans Wolf, Birgit Arabin, Christoph C Lees, Dick Oepkes, Federico Prefumo, Baskaran Thilaganathan, Tullia Todros, Gerard H A Visser, Caterina M Bilardo, Jan B Derks, Anke Diemert, Johannes J Duvekot, Enrico Ferrazzi, Tiziana Frusca, Kurt Hecher, Neil Marlow, Pasquale Martinelli, Eva Ostermayer, Aris T Papageorghiou, Hubertina C J Scheepers, Dietmar Schlembach, K T M Schneider, Adriana Valcamonico, Aleid van Wassenaer-Leemhuis, Wessel Ganzevoort
OBJECTIVES: To explore if in early fetal growth restriction (FGR) the longitudinal pattern of short-term fetal heart rate (FHR) variation (STV) can be used for identifying imminent fetal distress and if abnormalities of FHR registration associate with two-year infant outcome. METHODS: The original TRUFFLE study assessed if in early FGR the use of ductus venosus Doppler pulsatility index (DVPI), in combination with a safety-net of very low STV and / or recurrent decelerations, could improve two-year infant survival without neurological impairment in comparison to computerised cardiotocography (cCTG) with STV calculation only...
August 3, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27452438/placental-structural-abnormalities-have-detrimental-hemodynamic-consequences-in-a-rat-model-of-maternal-hyperglycemia
#11
Lara Lehtoranta, Olli Vuolteenaho, Jukka Laine, Lauri Polari, Eeva Ekholm, Juha Räsänen
INTRODUCTION: Human type 1 diabetic pregnancy is associated with placental structural and hemodynamic abnormalities. We hypothesized that in rat fetuses of hyperglycemic dams, placental and fetal blood flow velocity waveforms demonstrate compromised hemodynamics when compared to control fetuses, and these hemodynamic parameters correlate with placental structural abnormalities at near term gestation. METHODS: Streptozotocin-induced maternal hyperglycemia group comprised 10 dams with 107 fetuses and the control group 20 dams with 219 fetuses...
August 2016: Placenta
https://www.readbyqxmd.com/read/27363529/right-ventricular-outflow-tract-obstruction-in-complicated-monochorionic-twin-pregnancies
#12
S J Eschbach, L S T M Boons, E van Zwet, J M Middeldorp, F J C M Klumper, E Lopriore, A K K Teunissen, M E Rijlaarsdam, D Oepkes, A D J Ten Harkel, M C Haak
OBJECTIVE: Severe right Ventricular Outflow Tract Obstruction (RVOTO) is a complication in recipient twins in Twin-to-Twin-Transfusion Syndrome (TTTS), which requires post-partum follow-up or treatment. The objective of our study was to evaluate pregnancy characteristics of neonates with RVOTO in complicated monochorionic twin pregnancies. In the TTTS cases we aimed to determine the incidence and to construct a prediction model for the development of RVOTO. METHODS: An observational cohort study of all complicated monochorionic twin pregnancies with a post-partum neonatal diagnosis of RVOTO was performed...
July 1, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27197939/use-of-doppler-velocimetry-in-diagnosis-and-prognosis-of-intrauterine-growth-restriction-iugr-a-review
#13
I Aditya, V Tat, A Sawana, A Mohamed, R Tuffner, T Mondal
Intrauterine growth restriction (IUGR) is a condition which has been difficult to assess at an early stage, resulting in the delivery of children who have poor genetic growth potential. Currently, IUGR classification is based upon the system of ultrasound biometry. Doppler velocimetry allows the measurement of hemodynamic flow of major fetal vessels, comparing the flow indices and patterns of normal and IUGR cases. In this review, the effectiveness of Doppler velocimetry in assessing blood flow in major vessels including the umbilical artery, ductus venosus, and middle cerebral artery was studied for both diagnostic and prognostic screening of IUGR...
May 18, 2016: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/27182129/neonatal-mortality-in-dogs-prognostic-value-of-doppler-ductus-venosus-waveform-evaluation-preliminary-results
#14
Gabriele Barella, Stefano Faverzani, Massimo Faustini, Debora Groppetti, Alessandro Pecile
AIM: To define the prognostic value of Doppler ultrasonographic morphology of ductus venosus (DV) waveform on canine neonatal mortality. MATERIALS AND METHODS: Fifty-four healthy pregnant bitches underwent fetal ultrasonographic assessment. The DV waveforms were classified as diphasic (dDVw) or triphasic (tDVw) and compared with neonatal mortality. RESULTS: Ninety-three fetuses were evaluated. Twenty fetuses belonged to litters with neonatal mortality, in which tDVw was observed...
April 2016: Veterinary World
https://www.readbyqxmd.com/read/27132420/early-fetal-heart-ultrasonography-as-additional-indicator-for-chromosomopathies
#15
A Dmitrovic, K Jeremic, U M Babic, M Perovic, T Mihailovic, D Opric, N Zecevic, M Gojnić-Dugalić
OBJECTIVE: First trial of estimating values of scans of fetal heart structures (FHS) in first trimester of pregnancy, as more primary facts of possible chromosomopathies. MATERIALS AND METHODS: The study included 2,643 fetuses that were examined in first trimester of pregnancy on Sono CT convex (C5-2MHz), endovaginal (ev 8-4MHz), and linear transducers (L12-5MHz) during a period of eight years. Fetal heart was evaluated using appropriate software with broad-band transducers and color Doppler, Sono CT, and HD ZOOM technologies...
2016: Clinical and Experimental Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27082710/placental-and-fetal-hemodynamics-in-prolonged-pregnancies
#16
Tuomas Kauppinen, Tiina Kantomaa, Aydin Tekay, Kaarin Mäkikallio
OBJECTIVE: We hypothesized that Doppler measurements of the placental and fetal central and peripheral hemodynamics would predict adverse outcomes in prolonged uncomplicated singleton pregnancies. METHOD: A total of 160 participants were recruited to this study. Doppler measurements of placental and fetal hemodynamics as well as cardiotocography (CTG) were assessed prior to induction of labor at >41+ weeks. CTG during delivery, umbilical artery (UA) pH and base excess at birth and neonatal data were evaluated...
July 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/27060369/absence-of-an-anatomical-origin-for-altered-ductus-venosus-flow-velocity-waveforms-in-first-trimester-human-fetuses-with-increased-nuchal-translucency
#17
Nicole B Burger, Alexandra Matias, Evelien Kok, Christianne J M de Groot, Vincent M Christoffels, Mireille N Bekker, Monique C Haak
OBJECTIVE: To perform a morphological evaluation of the ductus venosus, heart and jugular lymphatic sac (JLS) in first-trimester human fetuses with normal and abnormal ductus venosus flow velocity waveforms (DV-FVWs) and normal and increased nuchal translucency (NT). METHOD: Postmortem examination was performed on fetuses with increased NT or structural malformations with previous NT and DV-FVW measurements. Ductus venosus morphology was examined using markers for endothelium, smooth muscle actin (SMA), nerves and elastic fibers...
June 2016: Prenatal Diagnosis
https://www.readbyqxmd.com/read/26962562/the-usefulness-of-fetal-doppler-evaluation-in-early-versus-late-onset-intrauterine-growth-restriction-review-of-the-literature
#18
REVIEW
Daniel Mureșan, Ioana Cristina Rotar, Florin Stamatian
Intrauterine growth restriction (IUGR) represents a serious condition that can lead to increased perinatal morbidity, mortality and postnatal impaired neurodevelopment. There are two distinct phenotypes of IUGR: early onset and late onset IUGR with different onset, patterns of evolution and fetal Doppler profile. In early onset preeclampsia the main Doppler modifications are at the level of umbilical artery, with progressive augmentation of the pulsatility index to absent or reverse end diastolic flow. The modifications of the cerebral, cardiac and ductus venosus circulation are generally present, but with different sequences...
March 2016: Medical Ultrasonography
https://www.readbyqxmd.com/read/26946331/ductus-venosus-doppler-in-the-assessment-of-fetal-cardiovascular-health-an-updated-practical-approach
#19
REVIEW
Viola Seravalli, Jena L Miller, Dana Block-Abraham, Ahmet A Baschat
The ductus venosus has a central role in the distribution of highly oxygenated umbilical venous blood to the heart. Its waveform is related to the pressure-volume changes in the cardiac atria and it is therefore important in the monitoring of any fetal condition that may affect forward cardiac function. The cardiovascular parameters that can influence forward cardiac function include afterload, myocardial performance and preload. Decreased forward flow during atrial systole (a-wave) is the most sensitive and ubiquitous finding when any of these parameters is affected...
June 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/26939599/first-trimester-echocardiographic-features-and-perinatal-outcomes-in-fetuses-with-congenital-absence-of-the-aortic-valve
#20
Rong Yu, Sheng-li Li, Guo-yang Luo, Hua-xuan Wen, Shu-yuan Ouyang, Cong-ying Chen, Ying Yuan
OBJECTIVES: The purpose of this study was to describe the echocardiographic features and perinatal outcomes of congenital absence of the aortic valve diagnosed by first-trimester echocardiography. METHODS: This retrospective study assessed the feasibility of first-trimester echocardiography in detecting absence of the aortic valve. All cases of absence of the aortic valve diagnosed by first-trimester fetal echocardiography from January 2010 to December 2014 were identified at a single referral center using an established perinatal database...
April 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
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