Yuta Michimori, Rikihisa Izaki, Yu Su, Yuto Fukuyama, Shigeru Shimamura, Karin Nishimura, Yuya Miwa, Sotaro Hamakita, Takahiro Shimosaka, Yuki Makino, Ryo Takeno, Takaaki Sato, Haruki Beppu, Isaac Cann, Tamotsu Kanai, Takuro Nunoura, Haruyuki Atomi
Many organisms that utilize the Calvin-Benson-Bassham (CBB) cycle for autotrophic growth harbor metabolic pathways to remove and/or salvage 2-phosphoglycolate, the product of the oxygenase activity of ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco). It has been presumed that the occurrence of 2-phosphoglycolate salvage is linked to the CBB cycle, and in particular, the C2 pathway to the CBB cycle and oxygenic photosynthesis. Here, we examined 2-phosphoglycolate salvage in the hyperthermophilic archaeon Thermococcus kodakarensis , an obligate anaerobe that harbors a Rubisco that functions in the pentose bisphosphate pathway...
April 16, 2024: Proceedings of the National Academy of Sciences of the United States of America