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Narrative medicine

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https://www.readbyqxmd.com/read/28105334/chronic-kidney-disease-in-children-and-the-role-of-epigenetics-future-therapeutic-trajectories
#1
Samuel N Uwaezuoke, Henrietta U Okafor, Vivian N Muoneke, Odutola I Odetunde, Chioma L Odimegwu
Global differences in the observed causes of chronic kidney disease (CKD) in children are well documented and are attributed to dissimilarities in clime, race, hereditary, and ancestry. Thus, familial clustering and disparities in CKD prevalence rates across ethnic and racial groups indicate that the progression of renal disease has a strong genetic component. Mammalian studies have demonstrated a feasible nexus between nutrition and non-genetic exposure (around the time of conception and in epigenetic changes) in the expression of major genes identified in renal organogenesis...
December 2016: Biomedical Reports
https://www.readbyqxmd.com/read/28099548/teledermatology-in-tijuana-mexico
#2
Megan Brown
The Health Frontiers in Tijuana (HFiT) clinic is a binational partnership between the University of California, San Diego School of Medicine (San Diego, California); the Universidad Autónoma de Baja California School of Medicine (Tijuana, Mexico); and Desayunador Salesiano Padre Chava, a community grassroots organization in Tijuana, Mexico. Health Frontiers in Tijuana provides accessible quality health care for the underserved in Tijuana's Zona Norte. This article is a narrative meant to share my clinical experience as a dermatology resident who worked with HFiT to establish teledermatology services at this clinic...
December 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28096036/a-guide-to-the-anti-innovation-pharmaphobia-narrative-for-the-aspiring-innovator
#3
Thomas P Stossel
Thomas P. Stossel is an American Cancer Society Professor of Medicine Emeritus at Harvard Medical School, Honorary Physician in the Hematology Division of Brigham & Women's Hospital, founding scientist of BioAegis Therapeutics, Visiting Scholar of The American Enterprise Institute and cofounder of Options for Children in Zambia.
February 2017: Surgery
https://www.readbyqxmd.com/read/28095476/a-systematic-review-of-ebola-treatment-trials-to-assess-the-extent-to-which-they-adhere-to-ethical-guidelines
#4
Thomas Richardson, Andrew McDonald Johnston, Heather Draper
BACKGROUND: Objective: To determine to what extent each trial met criteria specified in three research frameworks for ethical trial conduct. Design: Systematic review and narrative analysis. METHODS AND FINDINGS: Data sources: MEDBASE and EMBASE databases were searched using a specific search strategy. The Cochrane database for systematic reviews, the PROSPERO database and trial registries were examined. A grey literature search and citation search were also carried out...
2017: PloS One
https://www.readbyqxmd.com/read/28093833/cracking-the-code-residents-interpretations-of-written-assessment-comments
#5
Shiphra Ginsburg, Cees Pm van der Vleuten, Kevin W Eva, Lorelei Lingard
CONTEXT: Interest is growing in the use of qualitative data for assessment. Written comments on residents' in-training evaluation reports (ITERs) can be reliably rank-ordered by faculty attendings, who are adept at interpreting these narratives. However, if residents do not interpret assessment comments in the same way, a valuable educational opportunity may be lost. OBJECTIVES: Our purpose was to explore residents' interpretations of written assessment comments using mixed methods...
January 16, 2017: Medical Education
https://www.readbyqxmd.com/read/28093443/impact-of-advanced-autonomous-non-medical-practitioners-in-emergency-care-protocol-for-a-scoping-study
#6
Mark Sujan, Hannah Howard-Franks, Garry Swann, Kirsti Soanes, Catherine Pope, Robert Crouch, Sophie Staniszewska, Elaine Maxwell, Huayi Huang, Matthew Cooke
INTRODUCTION: Emergency care services are looking for new models of care delivery to deal with changing patient demographics and increased pressures. It has been suggested that advanced non-medical practitioners might be valuable for delivering such new models of care. However, it is not clear what the impact of the deployment of advanced non-medical practitioners in emergency care is. This scoping study addresses the following research question: What is known from the literature about the different types of impact of the deployment of advanced (autonomous) non-medical practitioners in emergency care? METHODS AND ANALYSIS: A scoping study will be undertaken to examine and map the impact of the deployment of advanced non-medical practitioners in emergency care...
January 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28086924/treating-infants-with-frigg-linking-disease-aetiologies-medicinal-plant-use-and-care-seeking-behaviour-in-southern-morocco
#7
Irene Teixidor-Toneu, Gary J Martin, Rajindra K Puri, Ahmed Ouhammou, Julie A Hawkins
BACKGROUND: Although most Moroccans rely to some extent on traditional medicine, the practice of frigg to treat paediatric ailments by elderly women traditional healers known as ferraggat, has not yet been documented. We describe the role of these specialist healers, document the medicinal plants they use, and evaluate how and why their practice is changing. METHODS: Ethnomedicinal and ethnobotanical data were collected using semi-structured interviews and observations of medical encounters...
January 13, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28078766/lost-in-transformation-reviving-ethics-of-care-in-hospital-cultures-of-evidence-based-healthcare
#8
Annelise Norlyk, Anita Haahr, Pia Dreyer, Bente Martinsen
Drawing on previous empirical research, we provide an exemplary narrative to illustrate how patients have experienced hospital care organized according to evidence-based fast-track programmes. The aim of this paper was to analyse and discuss if and how it is possible to include patients' individual perspectives in an evidence-based practice as seen from the point of view of nursing theory. The paper highlights two conflicting courses of development. One is a course of standardization founded on evidence-based recommendations, which specify a set of rules that the patient must follow rigorously...
January 12, 2017: Nursing Inquiry
https://www.readbyqxmd.com/read/28068187/a-century-of-surgical-innovation-at-a-boston-hospital
#9
JaBaris D Swain, Gaurav Sharma, Rowza T Rumma, P Marco Fisichella, Edward Whang
BACKGROUND: Innovation has been a central focus of the Department of Surgery at the Brigham and Women's Hospital since its very inception. Here we review examples of innovations originating in this Department and analyze factors that have been critical to successful innovation. Finally, we discuss challenges to sustainability of innovation in this Department. METHODS: Narrative review of the literature, interviews, and personal observations. RESULTS: Examples of innovations reviewed here were each dependent on three critical elements: 1) multidisciplinary collaboration among surgical innovators and individuals outside of surgery who offered complementary skills and expertise, 2) a rich institutional environment that sustained a diverse complement of innovators working in close proximity, and 3) Department Chairmen who facilitated the work of innovators and promoted their contributions, rather than seeking personal prestige or financial gain...
January 9, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28065444/investigating-patient-narratives-posted-on-internet-and-their-informativeness-level-for-pharmacovigilance-purpose-the-example-of-comments-about-statins
#10
Farid Kheloufi, Anne Default, Olivier Blin, Joelle Micallef
AIM OF THE STUDY: Health-related networks like patient health forums may be considered as potential sources of information to early detect pharmacovigilance issues or complete data on drug safety. However, the clinical and pharmacological relevancy of such a source has not been clearly explored. We aimed to describe the characteristics and the informativeness level of Internet narratives posted by patients and mentioning adverse drug reactions (ADRs) related to statins. METHODS: A retrospective cross-sectional study was conducted on an Internet website dedicated to share experience on medicines...
December 9, 2016: Thérapie
https://www.readbyqxmd.com/read/28064252/philosophical-provocation-the-lifeblood-of-clinical-ethics
#11
Laurence B McCullough
The daily work of the clinical ethics teacher and clinical ethics consultant falls into the routine of classifying clinical cases by ethical type and proposing ethically justified alternatives for the professionally responsible management of a specific type of case. Settling too far into this routine creates the risk of philosophical inertia, which is not good either for the clinical ethicist or for the field of clinical ethics. The antidote to this philosophical inertia and resultant blinkered vision of clinical ethics is sustained, willing exposure to philosophical provocation...
February 2017: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/28052177/battlefield-acupuncture-is-it-ready-for-widespread-dissemination
#12
Daniel G Federman, Craig G Gunderson
The use of prescription opioids for chronic pain has increased markedly within the past few decades; thus, death rates associated with opioid overdoses have increased dramatically. Nonopioid pharmacologic therapies also are associated with adverse effects. Other pain-abatement modalities such as acupuncture may be useful in the treatment of several painful conditions. Battlefield acupuncture is being promulgated as a potential low-risk, nonpharmacological therapy for pain. In this narrative review we examine the published literature to support battlefield acupuncture...
January 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28052168/a-review-of-tenure-for-black-latino-and-native-american-faculty-in-academic-medicine
#13
Zedeena E Fisher, José E Rodríguez, Kendall M Campbell
OBJECTIVES: Tenure policies in US medical schools have been under scrutiny for decades while black/African American, Latino, and Native American faculty continue to be underrepresented in medicine. As medical institutions seek to improve diversity, tenure continues to be a major retention tool. We undertook a systematic review of the literature to investigate the role that tenure plays in the recruitment, retention, and advancement of underrepresented minorities in medicine (URMM) faculty in academic medicine...
January 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/28050803/access-to-controlled-medicines-for-anesthesia-and-surgical-care-in-low-income-countries-a-narrative-review-of-international-drug-control-systems-and-policies
#14
Jason W Nickerson, Katherine Pettus, Kathleen E Wheeler, Christopher Hallam, David R Bewley-Taylor, Amir Attaran, Adrian W Gelb
PURPOSE: This article describes the functioning of the international drug control system, its integration into national legislation and policy, and the collective impact on access to medicines. SOURCE: We conducted a review of the three international drug control conventions, peer-reviewed articles, and grey literature known to the authors that describes national and international drug control systems and their impact on access to controlled medicines. This review was supplemented with literature derived from a structured search of MEDLINE(®) for articles relating to medical uses of ketamine in low- and middle-income countries conducted to strengthen an advocacy campaign...
January 3, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28050797/debates-about-conflict-of-interest-in-medicine-deconstructing-a-divided-discourse
#15
Serena Purdy, Miles Little, Christopher Mayes, Wendy Lipworth
The pharmaceutical industry plays an increasingly dominant role in healthcare, raising concerns about "conflicts of interest" (COI) on the part of the medical professionals who interact with the industry. However, there is considerable disagreement over the extent to which COI is a problem and how it should be managed. Participants in debates about COI have become entrenched in their views, which is both unproductive and deeply confusing for the majority of medical professionals trying to work in an increasingly commercialized environment...
January 3, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28049486/towards-eliminating-malaria-in-high-endemic-countries-the-roles-of-community-health-workers-and-related-cadres-and-their-challenges-in-integrated-community-case-management-for-malaria-a-systematic-review
#16
REVIEW
Bruno F Sunguya, Linda B Mlunde, Rakesh Ayer, Masamine Jimba
BACKGROUND: Human resource for health crisis has impaired global efforts against malaria in highly endemic countries. To address this, the World Health Organization (WHO) recommended scaling-up of community health workers (CHWs) and related cadres owing to their documented success in malaria and other disease prevention and management. Evidence is inconsistent on the roles and challenges they encounter in malaria interventions. This systematic review aims to summarize evidence on roles and challenges of CHWs and related cadres in integrated community case management for malaria (iCCM)...
January 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28048638/tu-d-201-04-veracity-of-data-elements-in-radiation-oncology-incident-learning-systems
#17
A Kapur, S Evans, D Brown, G Ezzell, D Hoopes, S Dieterich, K Kapetanovic, C Tomlinson
PURPOSE: Incident learning systems encompass volumes, varieties, values, and velocities of underlying data elements consistent with the V's of big data. Veracity, the 5th V however exists only if there is high inter-rater reliability (IRR) within the data elements. The purpose of this work was to assess IRR in the nationally deployed RO-ILS: Radiation Oncology-Incident Learning System (R) sponsored by the American Society for Radiation Oncology (ASTRO) and the American Association of Physicists in Medicine (AAPM)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28041712/broken-heart-tako-tsubo-or-stress-cardiomyopathy-metaphors-meanings-and-their-medical-impact
#18
REVIEW
Thomas Efferth, Mita Banerjee, Norbert W Paul
The cardiac impact of psychological stress historically and socially understood as boundary experiences of human life has long since become an icon. From the aching heart to the sudden death provoked by awe, horror, grief, anger, and humiliation on one side and extreme enchantment, enthusiasm, and excitement on the other, the broken heart has become a globally recognized and powerful metaphor present from folklore to popular culture to high literature and back to everyday communication. In medicine, the "broken heart syndrome" is described as a relatively new nosological entity that has been used synonymously with the term tako-tsubo or stress cardiomyopathy...
December 22, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28033447/assessment-of-overall-survival-quality-of-life-and-safety-benefits-associated-with-new-cancer-medicines
#19
Sebastian Salas-Vega, Othon Iliopoulos, Elias Mossialos
Importance: There is a dearth of evidence examining the impact of newly licensed cancer medicines on therapy. This information could otherwise support clinical practice, and promote value-based decision-making in the cancer drug market. Objective: To evaluate the comparative therapeutic value of all new cancer medicines approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) between 2003 and 2013. Design, Setting, and Participants: We used a narrative synthesis approach to systematically synthesize and analyze English, French, and Australian health technology assessments (HTAs) of all new cancer medicines licensed in the United States and Europe between 2003 and 2013...
December 29, 2016: JAMA Oncology
https://www.readbyqxmd.com/read/28031934/stories-of-experiences-of-care-for-growth-hormone-deficiency-the-crescere-project
#20
Maria G Marini, Paola Chesi, Laura Mazzanti, Laura Guazzarotti, Teresa D Toni, Maria C Salerno, Annunziata Officioso, Maria Parpagnoli, Cristina Angeletti, Maria F Faienza, Maria L Iezzi, Tommaso Aversa, Cinzia Sacchetti
AIMS: Growth hormone deficiency therapy is demanding for patients and caregivers. Teams engaged in the clinical management of growth hormone deficiency therapy need to know how families live with this condition, to provide an adequate support and prevent the risk of withdrawal from therapy. METHODS: Using Narrative Medicine, testimonies from patients, their parents and providers of care were collected from 11 Italian centers. Narrations were analyzed throughout an elaboration of recurring words and expressions...
March 2016: Future Science OA
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