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https://www.readbyqxmd.com/read/29153523/uncertainty-assessment-of-the-breath-methane-concentration-method-to-determine-methane-production-of-dairy-cows
#1
Liansun Wu, Peter W G Groot Koerkamp, Nico Ogink
The breath methane concentration method uses the methane concentrations in the cow's breath during feed bin visits as a proxy for the methane production rate. The objective of this study was to assess the uncertainty of a breath methane concentration method in a feeder and its capability to measure and rank cows' methane production. A range of controlled methane fluxes from a so-called artificial reference cow were dosed in a feed bin, and its exhaled air was sampled by a tube inside the feeder and analyzed...
November 15, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29150612/health-impact-of-e-cigarettes-a-prospective-3-5-year-study-of-regular-daily-users-who-have-never-smoked
#2
Riccardo Polosa, Fabio Cibella, Pasquale Caponnetto, Marilena Maglia, Umberto Prosperini, Cristina Russo, Donald Tashkin
Although electronic cigarettes (ECs) are a much less harmful alternative to tobacco cigarettes, there is concern as to whether long-term ECs use may cause risks to human health. We report health outcomes (blood pressure, heart rate, body weight, lung function, respiratory symptoms, exhaled breath nitric oxide [eNO], exhaled carbon monoxide [eCO], and high-resolution computed tomography [HRCT] of the lungs) from a prospective 3.5-year observational study of a cohort of nine daily EC users (mean age 29.7 (±6...
November 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29146889/exhaled-markers-of-anti-oxidant-activity-and-oxidative-stress-in-stable-cystic-fibrosis-patients-with-moderate-lung-disease
#3
Lucia Spicuzza, Giuseppe Fabio Parisi, Lucia Tardino, Nicola Ciancio, Raffaella Nenna, Fabio Midulla, Salvatore Leonardi
The sustained imbalance between oxidant and antioxidant species contributes to lung damage in patients with cystic fibrosis (CF). Glutathione (GSH) is an important component of the antioxidant defense in the airways epithelial lining fluid and its transportation out of the cells may be altered in CF. The aim of this study was to assess the oxidants/anti-oxidants balance in the airways of patients with CF. We measured the concentrations of GSH, the total antioxidant capacity and the concentration of 8-iso-prostaglandin F2α (8-isoprostane), a marker of oxidative stress, in the exhaled breath condensate of 17 non-smoking patients with CF, in stable phase, and in 17 age-matched healthy subjects...
November 17, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/29145814/elevated-exhaled-acetone-concentration-in-stage-c-heart-failure-patients-with-diabetes-mellitus
#4
Tetsuro Yokokawa, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Akiomi Yoshihisa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-Ichi Saitoh, Takafumi Ishida, Akito Shimouchi, Yasuchika Takeishi
BACKGROUND: Breath acetone is a noninvasive biomarker of heart failure; however, its significance in heart failure patients with diabetes mellitus has yet to be clarified. The objective of this study is to investigate whether exhaled acetone concentration is a noninvasive biomarker in heart failure patients with diabetes mellitus. METHODS: This study prospectively included 35 diabetic patients with stage C heart failure and 20 diabetic patients with or at risk of heart failure (stage A or B)...
November 16, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29142292/urinary-volatile-organic-compounds-in-overweight-compared-to-normal-weight-children-results-from-the-italian-i-family-cohort
#5
Rosaria Cozzolino, Beatrice De Giulio, Pasquale Marena, Antonella Martignetti, Kathrin Günther, Fabio Lauria, Paola Russo, Matteo Stocchero, Alfonso Siani
Accumulating evidence shows that urinary volatile organic compounds (VOCs) could be perturbed in many physiological and pathological states, including several diseases and different dietary exposures. Few studies investigated the urinary metabolic signature associated to excess body weight and obesity in adult populations, while a different VOCs profile was found in exhaled breath in obese as compared to lean children. Aim of this study was to evaluate the VOCs profile in the urine of 21 overweight/obese (OW/Ob) and 28 normal-weight (NW) children belonging to the Italian cohort of the I...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29137702/review-of-recent-developments-in-determining-volatile-organic-compounds-in-exhaled-breath-as-biomarkers-for-lung-cancer-diagnosis
#6
REVIEW
Jiemin Zhou, Zi-Ao Huang, Ujendra Kumar, David D Y Chen
Lung cancer is the most common cause of cancer deaths, its global incidence is rising, and continuing rises are predicted. The potential to diagnose lung cancers based on the determination of volatile organic compounds (VOCs) in human breath has been attracting increasing attention with the development of new techniques and methodologies. However, despite many reports of VOC profiling in lung cancer patients, little is known about how specific biomarkers relate to the biochemical pathways involved in lung cancer development, and there is still no reliable method for diagnosing lung cancer at the early stages...
December 15, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29131420/chromatographic-analysis-of-voc-patterns-in-exhaled-breath-from-smokers-and-nonsmokers
#7
Simonetta Capone, Maria Tufariello, Angiola Forleo, Valentina Longo, Lucia Giampietruzzi, Antonio Vincenzo Radogna, Flavio Casino, Pietro Siciliano
Cigarette smoking harms nearly every organ of the body and causes many diseases. The analysis of exhaled breath for exogenous and endogenous Volatile Organic Compounds (VOCs) can provide fundamental information on active smoking and insight into the health damage that smoke is creating. Various exhaled Volatile Organic Compounds (VOCs) have been reported as typical of smoking habit and recent tobacco consumption, but to date, no eligible biomarkers have been identified. Aiming to identify such potential biomarkers, in this pilot study we analysed the chemical patterns of exhaled breath from 26 volunteers divided in groups of nonsmokers and subgroups of smokers sampled at different periods of withdrawal from smoking...
November 13, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29124506/heart-rate-variability-biofeedback-does-not-substitute-for-asthma-steroid-controller-medication
#8
Paul M Lehrer, Charles G Irvin, Shou-En Lu, Anthony Scardella, Beatrix Roehmheld-Hamm, Milisyaris Aviles-Velez, Jessica Graves, Evgeny G Vaschillo, Bronya Vaschillo, Flavia Hoyte, Harold Nelson, Frederick S Wamboldt
Despite previous findings of therapeutic effects for heart rate variability biofeedback (HRVB) on asthma, it is not known whether HRVB can substitute either for controller or rescue medication, or whether it affects airway inflammation. Sixty-eight paid volunteer steroid naïve study participants with mild or moderate asthma were given 3 months of HRVB or a comparison condition consisting of EEG alpha biofeedback with relaxing music and relaxed paced breathing (EEG+), in a two-center trial. All participants received a month of intensive asthma education prior to randomization...
November 9, 2017: Applied Psychophysiology and Biofeedback
https://www.readbyqxmd.com/read/29122314/blood-transcriptional-and-microrna-responses-to-short-term-exposure-to-disinfection-by-products-in-a-swimming-pool
#9
Almudena Espín-Pérez, Laia Font-Ribera, Karin van Veldhoven, Julian Krauskopf, Lutzen Portengen, Marc Chadeau-Hyam, Roel Vermeulen, Joan O Grimalt, Cristina M Villanueva, Paolo Vineis, Manolis Kogevinas, Jos C Kleinjans, Theo M de Kok
BACKGROUND: Swimming in a chlorinated pool results in high exposure levels to disinfection by-products (DBPs), which have been associated with an increased risk of bladder cancer. OBJECTIVES: By studying molecular responses at the blood transcriptome level we examined the biological processes associated with exposure to these compounds. METHODS: Whole-genome gene expression and microRNA analysis was performed on blood samples collected from 43 volunteers before and 2h after 40min swimming in an indoor chlorinated pool (PISCINAII study)...
January 2018: Environment International
https://www.readbyqxmd.com/read/29122260/effects-of-pleasant-olfactory-mental-imagery-on-the-arterial-oxygenation-in-patients-with-open-heart-surgery-a-randomized-controlled-trial
#10
Masoud Rezaei-Nodehi, Masoumeh Bagheri-Nesami, Seyed Afshin Shorofi, Jamshid Yazdani-Charati, Rahman Ghafari
BACKGROUND AND PURPOSE: Arterial hypoxemia is one of the most common respiratory complications following cardiac surgery. This study was intended to examine the effects of pleasant olfactory mental imagery on postoperative hypoxemia in patients undergoing open heart surgery. MATERIALS AND METHODS: This is a randomized controlled clinical trial. The sample consisted of 80 patients who were randomly assigned to either practice olfactory mental imagery (experimental group) or receive routine care (control group)...
November 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/29120608/biochemical-gas-sensors-biosniffers-using-forward-and-reverse-reactions-of-secondary-alcohol-dehydrogenase-for-breath-isopropanol-and-acetone-as-potential-volatile-biomarkers-of-diabetes-mellitus
#11
Po-Jen Chien, Takuma Suzuki, Masato Tsujii, Ming Ye, Isao Minami, Kanako Toda, Hiromi Otsuka, Koji Toma, Takahiro Arakawa, Kouji Araki, Yasuhiko Iwasaki, Kayoko Shinada, Yoshihiro Ogawa, Kohji Mitsubayashi
This study describes two biosniffers to determine breath acetone and isopropanol (IPA) levels and applies them for breath measurement in healthy subjects and diabetic patients. Secondary alcohol dehydrogenase (S-ADH) can reduce acetone and oxidize nicotinamide adenine dinucleotide (NADH to NAD(+)) in a weak acid environment. NADH can be excited by 340 nm excitation lights and subsequently emit 490 nm fluorescence. Therefore, acetone can be measured by the decrease in NADH fluorescence intensity. S-ADH can also oxidize IPA and reduce NAD(+) to NADH when it is in an alkaline environment...
November 9, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29114603/audiovisual-biofeedback-guided-breath-hold-improves-lung-tumor-position-reproducibility-and-volume-consistency
#12
Danny Lee, Peter B Greer, Carminia Lapuz, Joanna Ludbrook, Perry Hunter, Jameen Arm, Sean Pollock, Kuldeep Makhija, Ricky T O'Brien, Taeho Kim, Paul Keall
Purpose: Respiratory variation can increase the variability of tumor position and volume, accounting for larger treatment margins and longer treatment times. Audiovisual biofeedback as a breath-hold technique could be used to improve the reproducibility of lung tumor positions at inhalation and exhalation for the radiation therapy of mobile lung tumors. This study aimed to assess the impact of audiovisual biofeedback breath-hold (AVBH) on interfraction lung tumor position reproducibility and volume consistency for respiratory-gated lung cancer radiation therapy...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29111149/systematic-approaches-for-biodiagnostics-using-exhaled-air
#13
REVIEW
Pravin Shende, Jai Vaidya, Yogesh A Kulkarni, R S Gaud
The 21st century is witnessing a revolution in understanding the composition of human exhaled breath more deeply, as the "breathe-print" can provide significant information of various diseases and disorders. This review elucidates various breath analytical techniques applied in medical diagnosis. A quick, portable, simple, accurate, non-invasive and relatively inexpensive approach of this technique is the reason of its evolution as a new frontier in disease diagnosis. This review emphasizes on breath biomarkers and traditional approaches in techniques used for breath biosensors like GC-MS, SIFT-MS, PTR-MS, IMS, Optical Absorption, Sensor Arrays and Electronic noses along with other new approaches such as Enzyme Immunoassay, Fluorescent Bead Immunoassays, Polymerase Chain Reaction, Antibody Microarray...
October 27, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29104183/exhaled-breath-aerosol-eba-the-simplest-non-invasive-medium-for-public-health-and-occupational-exposure-biomonitoring
#14
Joachim D Pleil, Ariel Wallace, Michael C Madden
Exhaled breath collection has long been recognized as requiring the least invasive methods of the biological fluids and so is preferred for environmental and public health studies. This commentary describes how breath biomonitoring is generally preferred for certain logistical reasons in public health and occupational biomonitoring. Three different fractions of exhaled breath are considered: gas-phase, liquid condensate, and aerosols. The focus is on the exhaled breath aerosol (EBA) fraction and the development of targeted sampling and analysis methods...
November 6, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/29104182/lipid-peroxidation-in-cardiac-surgery-towards-consensus-on-biomonitoring-diagnostic-tools-and-therapeutic-implementation
#15
Rosalba Romano, Simona M Cristescu, Terence H Risby, Nandor Marczin
This review focuses on oxidative stress and more specifically lipid peroxidation in cardiac surgery, one of the fundamental theories of perioperative complications. We present the molecular pathways leading to lipid peroxidation and integrate analytical methods that allow detection of lipid peroxidation markers in the fluid phase with those focusing on volatile compounds in exhaled breath. In order to explore the accumulated data in the literature, we present a systematic review of quantitative analysis of malondialdehyde (MDA), a widely used lipid peroxidation product at various stages of cardiac surgery...
November 6, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/29103415/effectiveness-of-breathing-exercises-during-the-second-stage-of-labor-on-labor-pain-and-duration-a-randomized-controlled-trial
#16
Hilal Yuksel, Yasemin Cayir, Zahide Kosan, Kenan Tastan
BACKGROUND: Some research exists on the effect of non-pharmacological approaches for labor pain relief. However, there is limited information about effectiveness of breathing exercises in pregnant women to reduce maternal pain during labor. OBJECTIVE: To determine whether breathing exercises for pregnant women during the second stage of labor have beneficial effects on maternal pain, duration of labor, and the first-minute Appearance, Pulse, Grimace, Activity and Respiration (APGAR) scores...
November 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29101894/computational-fluid-dynamics-evaluation-of-excessive-dynamic-airway-collapse
#17
Shahab Taherian, Hamid Rahai, Bernardo Gomez, Thomas Waddington, Farhad Mazdisnian
BACKGROUND: Excessive dynamic airway collapse, which is often caused by the collapse of the posterior membrane wall during exhalation, is often misdiagnosed with other diseases; stents can provide support for the collapsing airways. The standard pulmonary function tests do not necessarily show change in functional breathing condition for evaluation of these type of diseases. METHODS: Flow characteristics through a patient's airways with excessive dynamic airway collapse have been numerically investigated...
November 1, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/29100548/an-investigation-into-the-range-dependence-of-target-delineation-strategies-for-stereotactic-lung-radiotherapy
#18
Dennis J Mohatt, John M Keim, Mathew C Greene, Ami Patel-Yadav, Jorge A Gomez, Harish K Malhotra
BACKGROUND: The "gold standard" approach for defining an internal target volume (ITV) is using 10 gross tumor volume (GTV) phases delineated over the course of one respiratory cycle. However, different sites have adopted several alternative techniques which compress all temporal information into one CT image set to optimize work flow efficiency. The purpose of this study is to evaluate alternative target segmentation strategies with respect to the 10 phase gold standard. METHODS: A Quasar respiratory motion phantom was employed to simulate lung tumor movement...
November 3, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/29098476/influence-of-air-pollution-on-airway-inflammation-and-disease-activity-in-childhood-systemic-lupus-erythematosus
#19
Andressa Guariento Ferreira Alves, Maria Fernanda de Azevedo Giacomin, Alfésio Luis Ferreira Braga, Adriana Maluf Elias Sallum, Luiz Alberto Amador Pereira, Luis Carlos Farhat, Fernando Louzada Strufaldi, Ana Julia de Faria Coimbra Lichtenfels, Tômas de Santana Carvalho, Naomi Kondo Nakagawa, Clovis Artur Silva, Sylvia Costa Lima Farhat
Exposure to fine particles may trigger pulmonary inflammation/systemic inflammation. The objective of this study was to investigate the association between daily individual exposure to air pollutants and airway inflammation and disease activity in childhood-onset systemic lupus erythematosus (cSLE) patients. A longitudinal panel study was carried out in 108 consecutive appointments with cSLE patients without respiratory diseases. Over four consecutive weeks, daily individual measures of nitrogen dioxide (NO2), fine particulate matter (PM2...
November 2, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29094751/evaluation-of-a-novel-waste-anaesthetic-gas-scavenger-device-for-use-during-recovery-from-anaesthesia
#20
R Tallent, J Corcoran, J Sebastian
Volatile anaesthetic agents are a potential occupational health hazard to theatre and recovery staff. Operating theatres and anaesthetic rooms are required to be equipped with scavenging systems, but recovery units often are not. We compared exhaled, spectrophotometric sevoflurane and desflurane concentrations 15 cm from the mouth ('patient breathing zone') and 91 cm laterally to the patient ('nurse work zone') in 120 patients after tracheal extubation who were consecutively allocated to either ISO-Gard mask oxygen/scavenging or standard oxygen mask, 0 min, 10 min and 20 min after arrival in the theatre recovery unit...
November 2, 2017: Anaesthesia
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