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Cartilage imaging

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https://www.readbyqxmd.com/read/29351654/what-is-the-role-of-imaging-in-the-clinical-diagnosis-of-osteoarthritis-and-disease-management
#1
Xia Wang, Win Min Oo, James M Linklater
While OA is predominantly diagnosed on the basis of clinical criteria, imaging may aid with differential diagnosis in clinically suspected cases. While plain radiographs are traditionally the first choice of imaging modality, MRI and US also have a valuable role in assessing multiple pathologic features of OA, although each has particular advantages and disadvantages. Although modern imaging modalities provide the capability to detect a wide range of osseous and soft tissue (cartilage, menisci, ligaments, synovitis, effusion) OA-related structural damage, this extra information has not yet favourably influenced the clinical decision-making and management process...
January 16, 2018: Rheumatology
https://www.readbyqxmd.com/read/29350636/imaging-of-pediatric-foot-disorders
#2
Alfonso Reginelli, Anna Russo, Fabrizio Turrizziani, Roberto Picascia, Elisa Micheletti, Vittoria Galeazzi, Umberto Russo, Assunta Sica, Fabrizio Cioce, Alberto Aliprandi, Andrea Giovagnoni, Salvatore Cappabianca
Infants and children undergo imaging studies to evaluate a wide variety of congenital and acquired disorders. Imaging protocols have to consider the patient's comfort, level of anxiety, and smaller size. The first imaging study is usually made with plain radiographs. The routine radiographic examination of the foot includes the anteroposterior (AP), lateral, and oblique projections. Magnetic Resonance Imaging (RMI) provides excellent anatomic detail of cartilage, vasculature and soft tissue thanks to superior soft tissue contrast and spatial resolution, so is valuable in many cases...
January 19, 2018: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29350537/cartilage-morphological-and-histological-findings-after-reconstruction-of-the-glenoid-with-an-iliac-crest-bone-graft
#3
Alexander Auffarth, Herbert Resch, Nicholas Matis, Martin Hudelmaier, Wolfgang Wirth, Rosemarie Forstner, Daniel Neureiter, Andreas Traweger, Philipp Moroder
BACKGROUND: The J-bone graft is presumably representative of iliac crest bone grafts in general and allows anatomic glenoid reconstruction in cases of bone defects due to recurrent traumatic anterior shoulder dislocations. As a side effect, these grafts have been observed to be covered by some soft, cartilage-like tissue when arthroscopy has been indicated after such procedures. PURPOSE: To evaluate the soft tissue covering of J-bone grafts by use of magnetic resonance imaging (MRI) and histological analysis...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29349977/-therapeutic-effects-of-internal-drainage-by-expanding-arthroscopic-gastrocnemius-semimembranosus-bursa-and-cyst-wall-resection-for-the-treatment-of-41-patients-with-popliteal-cysts
#4
Li-Chuang Wu, Hai-Bo Zhou, Chao Zhang, Lei Chen, Cai-Long Liu
OBJECTIVE: To investigate the clinical curative effects of internal drainage by expanding arthroscopic gastrocnemius-semimembranosus bursa(GSB) and cyst wall resection for the treatment of popliteal cysts. METHODS: A retrospective analysis of patients from May 2011 to December 2015. Arthroscopic treatment for 41 patients with popliteal fossa cysts, 18 males and 23 females, aged from 34 to 67 years old, averaged 42.6 years old. All the patients had preoperative magnetic resonance imagings to confirm the diagnosis and identify the valvular opening(Gastrocnemius-Semimembranosus bursa, GSB), as well as the associated intra-articular pathology...
April 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349030/augmentation-of-patellar-tendon-repair-with-autologous-semitendinosus-graft-porto-technique
#5
João Espregueira-Mendes, Renato Andrade, M J S Fredrick Michael, André Sarmento, Nuno Sevivas, Rui Rocha, Ricardo Bastos Filho
Patellar tendon ruptures can lead to significant functional deficiency of the extensor mechanism of the knee. These injuries, because of their inherent nature and associated complications, may require a complex treatment and remains a challenge for orthopaedic surgeons. Current surgical techniques present significant complications, including patellar fracture, damage to patellar articular cartilage, and abnormal patella height. This note describes a surgical technique to provide an additional reinforcement to the patellar tendon repair with a semitendinous autograft, without the necessity to perform any transosseous tunnels at the patella bone...
December 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29346825/magnetic-resonance-imaging-of-articular-cartilage-within-the-knee
#6
Erin C Argentieri, Alissa J Burge, Hollis G Potter
Magnetic resonance imaging (MRI) provides an effective and noninvasive means by which to evaluate articular cartilage within the knee. Existing techniques can be utilized to detect and monitor longitudinal changes in cartilage status due to injury or progression of degenerative disease. Quantitative MRI (qMRI) techniques can provide a metric by which to evaluate the efficacy of cartilage repair techniques and offer insight into the composition of cartilage and cartilage repair tissue. In this review, we provide background on MR signal generation and decay, the utility of morphologic MRI assessment, and qMRI techniques for the biochemical assessment of cartilage (dGEMRIC, T2, T2*, T1ρ, sodium, gagCEST)...
January 18, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29344988/recent-advances-in-articular-cartilage-evaluation-using-computed-tomography-and-magnetic-resonance-imaging
#7
REVIEW
B B Nelson, C E Kawcak, M F Barrett, C W McIlwraith, M W Grinstaff, L R Goodrich
Articular cartilage is a critical joint tissue and its evaluation remains a diagnostic challenge in horses. Coupled with a poor capacity for healing, early degenerative changes in articular cartilage are difficult to characterise using routine diagnostic imaging evaluations. Computed tomography (CT) and magnetic resonance imaging (MRI) both provide volumetric joint assessment and highlight morphologic and quantitative properties of articular cartilage, improving assessment of this essential tissue. While the use of CT and MRI for joint evaluation is not new, there still remains a shortage of literature and scientific studies on the ability of these methods to evaluate articular cartilage in the horse...
January 17, 2018: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29344807/inhibition-of-bone-resorption-by-bisphosphonates-interferes-with-orthodontically-induced-midpalatal-suture-expansion-in-mice
#8
Till Koehne, Bärbel Kahl-Nieke, Michael Amling, Heike Korbmacher-Steiner
OBJECTIVES: Craniofacial sutures are important growth sites for skull development and are sensitive to mechanical stress. In order to determine the role of bone resorption in stress-mediated sutural bone growth, midpalatal suture expansion was performed in mice receiving alendronate, an anti-resorptive bisphosphonate. MATERIALS AND METHODS: The midpalatal sutures of 8-week-old C57BL/6 mice were expanded by orthodontic wires over the period of 2 weeks. Mice with maxillary expansion without drug treatment as well as untreated animals served as controls...
January 18, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29342064/minimally-manipulated-bone-marrow-concentrate-compared-with-microfracture-treatment-of-full-thickness-chondral-defects-a-one-year-study-in-an-equine-model
#9
Constance R Chu, Lisa A Fortier, Ashley Williams, Karin A Payne, Taralyn M McCarrel, Megan E Bowers, Diego Jaramillo
BACKGROUND: Microfracture is commonly performed for cartilage repair but usually results in fibrocartilage. Microfracture augmented by autologous bone marrow concentrate (BMC) was previously shown to yield structurally superior cartilage repairs in an equine model compared with microfracture alone. The current study was performed to test the hypothesis that autologous BMC without concomitant microfracture improves cartilage repair compared with microfracture alone. METHODS: Autologous sternal bone marrow aspirate (BMA) was concentrated using a commercial system...
January 17, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29338820/preoperative-evaluation-of-the-grade-and-stability-of-osteochondritis-dissecans-of-the-knee-by-magnetic-resonance-imaging
#10
Cui Ren, Ning Lang, Wen Chen, Hui Shu Yuan
Objective To assess the diagnostic performance of magnetic resonance imaging (MRI) in the grading of osteochondritis dissecans (OCD) of the knee.Methods Totally 47 patients with OCD of the knee confirmed by arthroscopy were retrospectively enrolled in this study.The OCD lesions were classified into four stages according to classification system of the International Cartilage Repair Society.Two radiologists analyzed all MRI findings independently,and the results were compared with those of arthroscopy.Sensitivity,specificity,and accuracy were calculated...
December 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29337871/influence-of-kartogenin-on-chondrogenic-differentiation-of-human-bone-marrow-derived-mscs-in-2d-culture-and-in-co-cultivation-with-oa-osteochondral-explant
#11
Timea Spakova, Jana Plsikova, Denisa Harvanova, Marek Lacko, Stefan Stolfa, Jan Rosocha
Articular cartilage has limited capacity for natural regeneration and repair. In the present study, we evaluated kartogenin (KGN), a bioactive small heterocyclic molecule, for its effect on in vitro proliferation and chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells (hBMSCs) in monolayer culture and in co-culture models in vitro. OA osteochondral cylinders and hBMSCs were collected during total knee replacement. The effect of KGN on hBMSCs during 21 days of culture was monitored by real-time proliferation assay, immunofluorescence staining, histological assay, scanning electron microscopy (SEM) (imaging and multiplex enzyme-linked immunosorbent assay) ELISA assay...
January 16, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29337647/compositional-assessment-of-human-tracheal-cartilage-by-infrared-spectroscopy
#12
Gary Linkov, Arash Hanifi, Farzad Yousefi, Derrick Tint, Sudheer Bolla, Nathanial Marchetti, Ahmed M S Soliman, Nancy Pleshko
Objectives To assess the potential of infrared fiber-optic spectroscopy to evaluate the compositional properties of human tracheal cartilage. Study Design Laboratory-based study. Methods Twenty human cadaveric distal tracheas were harvested (age range 20-78 years; 6 females, 14 males) for compositional analysis. Histologic staining, Fourier transform infrared imaging spectroscopy data on collagen and proteoglycan (PG) content, and near-infrared (NIR) fiber-optic probe spectroscopic data that reflect protein and water content were evaluated...
January 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29336368/glycosaminoglycan-content-of-the-lateral-compartment-cartilage-in-knees-conforming-to-the-indications-for-oxford-medial-unicompartmental-knee-arthroplasty
#13
Fu-Yin Wan, Ju-An Yue, Wan-Shou Guo, Lu-Yao Ma, Ran Yan, Qi-Dong Zhang, Li-Ming Cheng
BACKGROUND: The quality of the lateral compartment cartilage is important to preoperative evaluation and prognostic prediction of unicompartmental knee arthroplasty (UKA). Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) enables noninvasive assessment of glycosaminoglycan (GAG) content in cartilage. This study aimed to determine the GAG content of the lateral compartment cartilage in knees scheduled to undergo Oxford medial UKA. METHODS: From December 2016 to May 2017, twenty patients (20 osteoarthritic knees) conforming to the indications for Oxford medial UKA were included as the osteoarthritis (OA) group, and 20 healthy volunteers (20 knees) paired by sex, knee side, age (±3 years), and body mass index (BMI) (±3 kg/m2) were included as the control group...
January 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29334180/nitric-oxide-dependent-degradation-of-polyethylene-glycol-modified-single-walled-carbon-nanotubes-implications-for-intra-articular-delivery
#14
Kunal Bhattacharya, Cristiano Sacchetti, Pedro M Costa, Jens Sommertune, Birgit D Brandner, Andrea Magrini, Nicola Rosato, Nunzio Bottini, Massimo Bottini, Bengt Fadeel
Polyethylene glycol (PEG)-modified carbon nanotubes have been successfully employed for intra-articular delivery in mice without systemic or local toxicity. However, the fate of the delivery system itself remains to be understood. In this study 2 kDa PEG-modified single-walled carbon nanotubes (PNTs) are synthesized, and trafficking and degradation following intra-articular injection into the knee-joint of healthy mice are studied. Using confocal Raman microspectroscopy, PNTs can be imaged in the knee-joint and are found to either egress from the synovial cavity or undergo biodegradation over a period of 3 weeks...
January 15, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29333118/the-relationship-between-chondromalacia-patella-medial-meniscal-tear-and-medial-periarticular-bursitis-in-patients-with-osteoarthritis
#15
Mustafa Resorlu, Davut Doner, Ozan Karatag, Canan Akgun Toprak
Background: This study investigated the presence of bursitis in the medial compartment of the knee (pes anserine, semimembranosus-tibial collateral ligament, and medial collateral ligament bursa) in osteoarthritis, chondromalacia patella and medial meniscal tears. Patients and methods: Radiological findings of 100 patients undergoing magnetic resonance imaging with a preliminary diagnosis of knee pain were retrospectively evaluated by two radiologists. The first radiologist assessed all patients in terms of osteoarthritis, chondromalacia patella and medial meniscal tear...
December 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/29330619/mr-arthrography-of-the-hip-diagnostic-performance-and-image-quality-of-3d-steady-state-free-precession-versus-2d-turbo-spin-echo-sequences
#16
Mareen Sarah Kraus, Mike Notohamiprodjo, Sasan Partovi, Ahmed Sobieh, Andrea Baur-Melnyk, Joerg Hausdorf, Ulrich Grosse
OBJECTIVE: To retrospectively compare the diagnostic performance of isotropic 3D steady-state free precession (3D-SSFP) sequences with 2D turbo spin-echo proton density-weighted fat-saturated (2D-TSE-PD fs) images in hip magnetic resonance arthrography; arthroscopy was a standard of reference. METHODS: Eighty-one patients with suspected labral tears who underwent hip MR arthrography (3-T scanner) were included. 2D-TSE-PD fs sequences were acquired in three planes and a singular sagittal 3D-SSFP...
January 12, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29329888/associations-between-cartilage-proteoglycan-density-and-patient-outcomes-12months-following-anterior-cruciate-ligament-reconstruction
#17
Brian Pietrosimone, Daniel Nissman, Darin A Padua, J Troy Blackburn, Matthew S Harkey, Robert A Creighton, Ganesh M Kamath, Kaitlin Healy, Randy Schmitz, Jeffrey B Driban, Steve W Marshall, Joanne M Jordan, Jeffrey T Spang
BACKGROUND: Lower proteoglycan density (PGD) of the articular cartilage may be an early marker of osteoarthritis following anterior cruciate ligament (ACL) reconstruction (ACL-R). The purpose this study was to determine associations between the Knee Injury and Osteoarthritis Outcomes Score (KOOS) and PGD of the articular cartilage in the femur and tibia 12-months following ACL-R. METHODS: We evaluated KOOS pain, symptoms, function in activities of daily living (ADL), function in sport and recreation (Sport), and quality of life (QOL), as well as PGD using T1rho magnetic resonance imaging in 18 individuals 12...
January 9, 2018: Knee
https://www.readbyqxmd.com/read/29326025/how-age-and-frequency-impact-the-thyroid-cartilages-of-professional-singers
#18
Fabian Unteregger, Jan Thommen, Flurin Honegger, Silke Potthast, Salome Zwicky, Claudio Storck
OBJECTIVES/HYPOTHESIS: Young professional singers can easily reach very high pitches. In contrast, older singers often complain that they have to exert substantially more laryngopharyngeal force to reach the same high pitch compared with their earlier years. Various factors such as the property changes of the mucosa and ossification that impact the singing apparatus were suggested as explanations in the literature. The aim of this study was to analyze thyroid deformation-and thereby stiffness indirectly-during singing as a potential reason for this phenomenon...
January 8, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29324473/chondromyxoid-fibroma-arising-in-craniofacial-sites-a-clinicopathologic-analysis-of-25-cases
#19
David M Meredith, Christopher D M Fletcher, Vickie Y Jo
Chondromyxoid fibroma (CMF) is a rare benign tumor, usually arising in the metaphysis of long bones in young adults. Occurrence in craniofacial bones presents a particular diagnostic challenge given its unusual location and resemblance to malignant mimics. We describe the clinicopathologic features of 25 cases of craniofacial CMF identified between 1999 and 2017. Patients were 14 men and 11 women, with median age of 44 years (range, 5 to 83 y). Sites of involvement were sphenoid (7), ethmoid (5), maxilla (3), occipital (2), nasal septum (2), palatine (2), temporal (2), orbit (1), and undisclosed skull (1)...
January 10, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29323942/comparison-of-juvenile-allogenous-articular-cartilage-and-bone-marrow-aspirate-concentrate-versus-microfracture-with-and-without-bone-marrow-aspirate-concentrate-in-arthroscopic-treatment-of-talar-osteochondral-lesions
#20
Sydney C Karnovsky, Bridget DeSandis, Amgad M Haleem, Carolyn M Sofka, Martin O'Malley, Mark C Drakos
BACKGROUND: The purpose of this study was to compare the functional and radiographic outcomes of patients who received juvenile allogenic chondrocyte implantation with autologous bone marrow aspirate (JACI-BMAC) for treatment of talar osteochondral lesions with those of patients who underwent microfracture (MF). METHODS: A total of 30 patients who underwent MF and 20 who received DeNovo NT for JACI-BMAC treatment between 2006 and 2014 were included. Additionally, 17 MF patients received supplemental BMAC treatment...
January 1, 2018: Foot & Ankle International
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