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Cartilage imaging

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https://www.readbyqxmd.com/read/28936540/-chondral-and-osteochondral-defects-representation-by-imaging-methods
#1
REVIEW
S Nebelung, B Rath, M Tingart, C Kuhl, S Schrading
Morphological imaging of cartilage at high resolution allows the differentiation of chondral and osteochondral lesions. Nowadays, magnetic resonance imaging is the principal diagnostic tool in the assessment of cartilage structure and composition. Conventional radiography, computed tomography, ultrasound or optical coherence tomography are adjunct diagnostic modalities in the assessment of cartilage pathologies. The present article discusses the up-to-date diagnostic practice of cartilage imaging in terms of its scientific basis and current clinical status, requirements, techniques and image interpretation...
September 21, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28935436/associations-between-mri-detected-early-osteophytes-and-knee-structure-in-older-adults-a-population-based-cohort-study
#2
Zhaohua Zhu, Laura L Laslett, Weiyu Han, Benny Antony, Feng Pan, Flavia Cicuttini, Graeme Jones, Changhai Ding
OBJECTIVES: To describe prevalence of osteophytes (OPs) detected only by magnetic resonance imaging (MRI) but not by standard X-ray in older adults and to evaluate longitudinal associations with knee structural changes. METHODS: 837 participants were randomly selected from the local community and had MRI scans to assess knee OPs and other structures. OPs detected only by MRI but not by standard X-ray were defined as MRI-detected early OPs (MRI-OPs for short). OPs detected by both MRI and X-ray were defined as established-OPs...
September 18, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28934883/contrast-enhanced-computed-tomography-enables-quantitative-evaluation-of-tissue-properties-at-intrajoint-regions-in-cadaveric-knee-cartilage
#3
Rachel C Stewart, Juuso T J Honkanen, Harri T Kokkonen, Virpi Tiitu, Simo Saarakkala, Antti Joukainen, Brian D Snyder, Jukka S Jurvelin, Mark W Grinstaff, Juha Töyräs
Objective The aim of this study was to investigate whether the concentration of the anionic contrast agent ioxaglate, as quantitated by contrast-enhanced computed tomography (CECT) using a clinical cone-beam CT (CBCT) instrument, reflects biochemical, histological, and biomechanical characteristics of articular cartilage imaged in an ex vivo, intact human knee joint. Design An osteoarthritic human cadaveric knee joint (91 years old) was injected with ioxaglate (36 mg I/mL) and imaged using CBCT over 61 hours of ioxaglate diffusion into cartilage...
October 2017: Cartilage
https://www.readbyqxmd.com/read/28934880/three-dimensional-bioprinting-and-its-potential-in-the-field-of-articular-cartilage-regeneration
#4
Vivian H M Mouser, Riccardo Levato, Lawrence J Bonassar, Darryl D D'Lima, Daniel A Grande, Travis J Klein, Daniel B F Saris, Marcy Zenobi-Wong, Debby Gawlitta, Jos Malda
Three-dimensional (3D) bioprinting techniques can be used for the fabrication of personalized, regenerative constructs for tissue repair. The current article provides insight into the potential and opportunities of 3D bioprinting for the fabrication of cartilage regenerative constructs. Although 3D printing is already used in the orthopedic clinic, the shift toward 3D bioprinting has not yet occurred. We believe that this shift will provide an important step forward in the field of cartilage regeneration. Three-dimensional bioprinting techniques allow incorporation of cells and biological cues during the manufacturing process, to generate biologically active implants...
October 2017: Cartilage
https://www.readbyqxmd.com/read/28934879/two-year-evaluation-of-osteochondral-repair-with-a-novel-biphasic-graft-saturated-in-bone-marrow-in-an-equine-model
#5
Taralyn M McCarrel, Sarah L Pownder, Susannah Gilbert, Matthew F Koff, Emme Castiglione, Ryan A Saska, Gino Bradica, Lisa A Fortier
Objective To evaluate a biphasic cartilage repair device (CRD) for feasibility of arthroscopic implantation, safety, biocompatibility, and efficacy for long-term repair of large osteochondral defects. Methods The CRD was press-fit into defects (10 mm diameter, 10 mm deep) created in the femoral trochlea of 12 horses. In the contralateral limb, 10 mm diameter full-thickness chondral defects were treated with microfracture (MFX). Radiographs were obtained pre- and postoperatively, and at 4, 12, and 24 months...
October 2017: Cartilage
https://www.readbyqxmd.com/read/28934866/initial-experience-with-synthetic-mri-of-the-knee-at-3t-comparison-with-conventional-t-1-weighted-imaging-and-t2-mapping
#6
Sunghoon Park, Kyu-Sung Kwack, Young Ju Lee, Sung-Min Gho, Hyun Young Lee
OBJECTIVE: To assess the feasibility and accuracy of synthetic magnetic resonance imaging (MRI) compared to conventional T1-weighted and multi-echo spin-echo (MESE) sequences for obtaining T2 values in the knee joint at 3 Tesla. METHODS: This retrospective study included 19 patients with normal findings in the knee joint who underwent both synthetic MRI and MESE pulse sequences for T2 quantification. T2 values of the two sequences at the articular cartilage, bone marrow, and muscle were measured...
September 21, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28933331/-comparison-of-the-arthroscopic-finding-in-the-knee-joint-and-the-mri-retrospective-study
#7
K Šimeček, P Látal, J Duda, M Šimeček
PURPOSE OF THE STUDY Our retrospective study presents the comparison of the preoperative magnetic resonance imaging of the knee joint - MRI - and the arthroscopic finding - ASC. Its aim is to find out how a positive or a negative finding of MRI corresponds with the operative finding and how much the experience of radiologist contributes to the conformity. MATERIAL AND METHODS The MRI findings of knee joints treated surgically at two departments in 2013 and 2014 were assessed. The MRI was performed in a total of 470 patients who subsequently underwent an arthroscopic surgery...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28929186/-when-is-cartilage-repair-successful
#8
REVIEW
M Raudner, M M Schreiner, S Röhrich, M Zalaudek, S Trattnig
Focal cartilage lesions are a cause of long-term disability and morbidity. After cartilage repair, it is crucial to evaluate long-term progression or failure in a reproducible, standardized manner. This article provides an overview of the different cartilage repair procedures and important characteristics to look for in cartilage repair imaging. Specifics and pitfalls are pointed out alongside general aspects. After successful cartilage repair, a complete, but not hypertrophic filling of the defect is the primary criterion of treatment success...
September 19, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28924827/dual-contrast-ct-method-enables-diagnostics-of-cartilage-injuries-and-degeneration-using-a-single-ct-image
#9
Annina E A Saukko, Juuso T J Honkanen, Wujun Xu, Sami P Väänänen, Jukka S Jurvelin, Vesa-Pekka Lehto, Juha Töyräs
Cartilage injuries may be detected using contrast-enhanced computed tomography (CECT) by observing variations in distribution of anionic contrast agent within cartilage. Currently, clinical CECT enables detection of injuries and related post-traumatic degeneration based on two subsequent CT scans. The first scan allows segmentation of articular surfaces and lesions while the latter scan allows evaluation of tissue properties. Segmentation of articular surfaces from the latter scan is difficult since the contrast agent diffusion diminishes the image contrast at surfaces...
September 18, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28919293/correlation-between-histological-and-ultrasonographic-findings-of-soft-tissue-tumors-to-verify-the-possibility-of-cell-like-resolution-in-ultrasonography
#10
Ching-Lan Wu, Yi-Chen Lai, Hsin-Kai Wang, Paul Chih-Hsueh Chen, Hong-Jen Chiou
BACKGROUND: The purpose of this study is to test the possibility of obtained cell-like resolution in soft tissue tumors on the basis of ultrasound echotexture. METHODS: This is a prospective study consisting of 57 patients (29 females and 28 males, age range: 9-83 years, average age: 44.5 years) with palpable soft tissue mass, referred from the Departments of Orthopedics and Oncology for ultrasound (US)-guided biopsy. The study was approved by the institutional review board (IRB) of our hospital...
September 14, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28915300/inflammation-in-osteoarthritis
#11
Salvador Vilá
Advances in the understanding of chondrocytes and the synovial membrane as targets of and participants in the inflammatory process in articular joints have provided insights into the role of inflammation in cartilage and subchondral bone injury in rheumatic diseases. Reports that describe the inflammatory cellular infiltration of synovial membranes in patients with osteoarthritis, studies that associate cartilage structural injury with synovial membrane inflammatory status, the development of new imaging modalities that quantitatively measure synovial membrane inflammation and basic science advances that explore inflammatory pathways in the synovial cavity all suggest that inflammation plays an important role in cartilage injury in osteoarthritis...
September 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28910722/analysis-of-in-vivo-articular-cartilage-contact-surface-of-the-knee-during-a-step-up-motion
#12
Peng Yin, Jing-Sheng Li, Willem A Kernkamp, Tsung-Yuan Tsai, Seung-Hoon Baek, Ali Hosseini, Lin Lin, Peifu Tang, Guoan Li
BACKGROUND: Numerous studies have reported on the tibiofemoral articular cartilage contact kinematics, however, no data has been reported on the articular cartilage geometry at the contact area. This study investigated the in-vivo tibiofemoral articular cartilage contact biomechanics during a dynamic step-up motion. METHODS: Ten healthy subjects were imaged using a validated magnetic resonance and dual fluoroscopic imaging technique during a step-up motion. Three-dimensional bone and cartilage models were constructed from the magnetic resonance images...
September 8, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28910438/long-term-outcomes-of-subtotal-septal-reconstruction-in-rhinoplasty
#13
Scott A Asher, Akta S Kakodkar, Dean M Toriumi
Importance: Significant nasal septal deviation may require complex reconstruction to achieve complete correction. Subtotal septal reconstruction is a method for addressing deviations in the L-strut. Objectives: To review the long-term outcomes of subtotal septal reconstruction and provide objective evidence of functional and aesthetic improvement. Design, Setting, and Participants: This medical record review obtained data on 144 patients who underwent subtotal septal reconstruction from September 1, 2008, to September 1, 2013...
September 14, 2017: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/28910133/a-comparison-of-2-year-outcomes-in-patients-undergoing-tibiofemoral-or-patellofemoral-matrix-induced-autologous-chondrocyte-implantation
#14
Jay R Ebert, Adrian Schneider, Michael Fallon, David J Wood, Gregory C Janes
BACKGROUND: Matrix-induced autologous chondrocyte implantation (MACI) has demonstrated encouraging clinical results in the treatment of knee chondral defects. However, earlier studies suggested that chondrocyte implantation in the patellofemoral (PF) joint was less effective than in the tibiofemoral (TF) joint. PURPOSE: To compare the radiological and clinical outcomes of those undergoing MACI to either the femoral condyles or PF joint. STUDY DESIGN: Cohort study; Level of evidence, 3...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28906396/chondrosarcoma-of-the-patella-a-case-report
#15
Conglin Ye, Zhiping Luo, Jin Zeng, Min Dai
RATIONALE: Chondrosarcoma, characterized by the production of cartilage matrix, is a common bone tumor, accounting for 20% to 27% of all malignant bone tumors. It often occurs in the cartilage of the pelvis, femur, tibia, and humerus. However, chondrosarcoma of the patella is extremely rare. PATIENT CONCERNS: The present study describes a case of chondrosarcoma affecting the right patella in a 68-year-old woman. The chief complaints were painful swelling and limitation of motion of the right knee for about half a year...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28903010/effect-of-loading-on-in-vivo-tibiofemoral-and-patellofemoral-kinematics-of-healthy-and-acl-reconstructed-knees
#16
Jarred M Kaiser, Michael F Vignos, Richard Kijowski, Geoffrey Baer, Darryl G Thelen
BACKGROUND: Although knees that have undergone anterior cruciate ligament reconstruction (ACLR) often exhibit normal laxity on clinical examination, abnormal kinematic patterns have been observed when the joint is dynamically loaded during whole body activity. This study investigated whether abnormal knee kinematics arise with loading under isolated dynamic movements. HYPOTHESIS: Tibiofemoral and patellofemoral kinematics of ACLR knees will be similar to those of the contralateral uninjured control knee during passive flexion-extension, with bilateral differences emerging when an inertial load is applied...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28899407/association-of-medial-meniscal-extrusion-with-medial-tibial-osteophyte-distance-detected-by-t2-mapping-mri-in-patients-with-early-stage-knee-osteoarthritis
#17
Shinnosuke Hada, Muneaki Ishijima, Haruka Kaneko, Mayuko Kinoshita, Lizu Liu, Ryo Sadatsuki, Ippei Futami, Anwajan Yusup, Tomohiro Takamura, Hitoshi Arita, Jun Shiozawa, Takako Aoki, Yuji Takazawa, Hiroshi Ikeda, Shigeki Aoki, Hisashi Kurosawa, Yasunori Okada, Kazuo Kaneko
BACKGROUND: Medial meniscal extrusion (MME) is associated with progression of medial knee osteoarthritis (OA), but no or little information is available for relationships between MME and osteophytes, which are found in cartilage and bone parts. Because of the limitation in detectability of the cartilage part of osteophytes by radiography or conventional magnetic resonance imaging (MRI), the rate of development and size of osteophytes appear to have been underestimated. Because T2 mapping MRI may enable us to evaluate the cartilage part of osteophytes, we aimed to examine the association between MME and OA-related changes, including osteophytes, by using conventional and T2 mapping MRI...
September 12, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28898105/gait-characteristics-associated-with-a-greater-increase-in-medial-knee-cartilage-t1%C3%AF-and-t2-relaxation-times-in-patients-undergoing-anterior-cruciate-ligament-reconstruction
#18
Hsiang-Ling Teng, Daniel Wu, Favian Su, Valentina Pedoia, Richard B Souza, C Benjamin Ma, Xiaojuan Li
BACKGROUND: Osteoarthritis of the medial tibiofemoral joint (MTFJ) is prevalent among patients undergoing anterior cruciate ligament reconstruction (ACLR). Magnetic resonance T1ρ and T2 relaxation times provide noninvasive methods to quantify early cartilage degeneration. Altered sagittal-plane gait biomechanics have been observed after ACLR, but their associations with longitudinal changes in MTFJ cartilage T1ρ and T2 remain unclear. Hypothesis/Purpose: To examine whether the peak knee flexion moment (KFM), knee flexion angle (KFA), and vertical ground-reaction force (vGRF) during gait are associated with prospective changes in medial tibiofemoral cartilage T1ρ and T2 in ACL-reconstructed knees and to compare these gait characteristics between patients undergoing ACLR and healthy control participants...
September 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28895760/application-of-a-semi-automatic-cartilage-segmentation-method-for-biomechanical-modeling-of-the-knee-joint
#19
Mimmi K Liukkonen, Mika E Mononen, Petri Tanska, Simo Saarakkala, Miika T Nieminen, Rami K Korhonen
Manual segmentation of articular cartilage from knee joint 3D magnetic resonance images (MRI) is a time consuming and laborious task. Thus, automatic methods are needed for faster and reproducible segmentations. In the present study, we developed a semi-automatic segmentation method based on radial intensity profiles to generate 3D geometries of knee joint cartilage which were then used in computational biomechanical models of the knee joint. Six healthy volunteers were imaged with a 3T MRI device and their knee cartilages were segmented both manually and semi-automatically...
September 12, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28894756/relationships-between-tibiofemoral-contact-forces-and-cartilage-morphology-at-2-to-3-years-after-single-bundle-hamstring-anterior-cruciate-ligament-reconstruction-and-in-healthy-knees
#20
David John Saxby, Adam L Bryant, Xinyang Wang, Luca Modenese, Pauline Gerus, Jason M Konrath, Kim L Bennell, Karine Fortin, Tim Wrigley, Flavia M Cicuttini, Christopher J Vertullo, Julian A Feller, Tim Whitehead, Price Gallie, David G Lloyd
BACKGROUND: Prevention of knee osteoarthritis (OA) following anterior cruciate ligament (ACL) rupture and reconstruction is vital. Risk of postreconstruction knee OA is markedly increased by concurrent meniscal injury. It is unclear whether reconstruction results in normal relationships between tibiofemoral contact forces and cartilage morphology and whether meniscal injury modulates these relationships. HYPOTHESES: Since patients with isolated reconstructions (ie, without meniscal injury) are at lower risk for knee OA, we predicted that relationships between tibiofemoral contact forces and cartilage morphology would be similar to those of normal, healthy knees 2 to 3 years postreconstruction...
August 2017: Orthopaedic Journal of Sports Medicine
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