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Complementary medicine

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https://www.readbyqxmd.com/read/29218996/use-of-complementary-and-alternative-medicine-among-newly-diagnosed-breast-cancer-patients-in-malaysia-an-early-report-from-the-mybcc-study
#1
Aina Farhana Zulkipli, Tania Islam, Nur Aishah Mohd Taib, Maznah Dahlui, Nirmala Bhoo-Pathy, Nabilla Al-Sadat, Hazreen Abdul Majid, Samsinah Hussain
BACKGROUND: The use of complementary and alternative medicine (CAM) has increased and little is known on CAM use during the initial period. Therefore, the aim was to determine prevalence of CAM use among newly diagnosed breast cancer patients prior to seeking conventional treatment. METHODS: This is a cross-sectional study involved interviewing newly diagnosed breast cancer patients in the University Malaya Medical Centre (UMMC) using a structured questionnaire...
December 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/29218886/clingen-cancer-somatic-working-group-standardizing-and-democratizing-access-to-cancer-molecular-diagnostic-data-to-drive-translational-research
#2
Subha Madhavan, Deborah Ritter, Christine Micheel, Shruti Rao, Angshumoy Roy, Dmitriy Sonkin, Matthew Mccoy, Malachi Griffith, Obi L Griffith, Peter Mcgarvey, Shashikant Kulkarni
A growing number of academic and community clinics are conducting genomic testing to inform treatment decisions for cancer patients (1). In the last 3-5 years, there has been a rapid increase in clinical use of next generation sequencing (NGS) based cancer molecular diagnostic (MolDx) testing (2). The increasing availability and decreasing cost of tumor genomic profiling means that physicians can now make treatment decisions armed with patient-specific genetic information. Accumulating research in the cancer biology field indicates that there is significant potential to improve cancer patient outcomes by effectively leveraging this rich source of genomic data in treatment planning (3)...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29218868/large-scale-integration-of-heterogeneous-pharmacogenomic-data-for-identifying-drug-mechanism-of-action
#3
Yunan Luo, Sheng Wang, Jinfeng Xiao, Jian Peng
A variety of large-scale pharmacogenomic data, such as perturbation experiments and sensitivity profiles, enable the systematical identification of drug mechanism of actions (MoAs), which is a crucial task in the era of precision medicine. However, integrating these complementary pharmacogenomic datasets is inherently challenging due to the wild heterogeneity, high-dimensionality and noisy nature of these datasets. In this work, we develop Mania, a novel method for the scalable integration of large-scale pharmacogenomic data...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29217726/the-association-between-the-use-of-biomedical-services-and-the-holistic-use-of-traditional-east-asian-medicine-a-national-survey-of-outpatients-in-south-korea
#4
Jae-Mahn Shim, Yun-Suk Lee
OBJECTIVES: The holistic use of a system of complementary and alternative medicine (CAM) is potentially linked to its treatment outcomes. This paper examines how the use of biomedicine is associated with the holistic use of CAM, focusing on traditional East Asian medicine (EM) that is uniquely integrated in the medical system in South Korea. DESIGN/SETTINGS: A representative national sample of EM outpatients in South Korea. PARTICIPANTS: 3861 survey respondents...
December 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/29214243/intracellular-investigation-on-the-differential-effects-of-4-polyphenols-on-mcf-7-breast-cancer-cells-by-raman-imaging
#5
A Mignolet, B R Wood, E Goormaghtigh
The past decades have seen significant interest in the study of polyphenolic compounds as potential therapeutic agents in medicine because they display a vast array of cellular effects beneficial to treat or manage a plethora of chronic diseases including inflammatory diseases, cardiovascular abnormalities and several types of cancer. These compounds act at different stages of carcinogenesis but deciphering their mode of action is a complex task. Live MCF-7 breast cancer cells were investigated using Raman imaging to evaluate the perturbations induced after incubating cells with four different polyphenols: EGCG, gallic acid, resveratrol and tannic acid...
December 7, 2017: Analyst
https://www.readbyqxmd.com/read/29213223/compositional-monosaccharide-analysis-of-morus-nigra-linn-by-hplc-and-hpce-quantitative-determination-and-comparison-of-polysaccharide-from-morus-nigra-linn-by-hpce-and-hplc
#6
Xiao-Li Ma, Feng Feng Song, Hui Zhang, Xie Huan, Song Ya Li
Background: Morus nigra Linn is not only treated as health food but also medicine in Chinese history. Objective: Here, we have extracted and separated the heteroglycan to monosaccharides of the dry fruits. Method: After heteroglycan being hydrolysised, then were we derivatived the monosaccharides with 1-phenyl-3-methyl-5-pyrazolone (PMP), and then subsequently HPCE and HPLC were used to separate. HPCE, which held an uncoated capillary (d=75μm) and detected by PDA at 245 nm with borate buffer, the voltage was set at 15 kV and capillary temperature was 25°C...
October 2017: Current Pharmaceutical Analysis
https://www.readbyqxmd.com/read/29210874/ischemic-stroke-patients-decision-making-process-in-their-use-of-western-medicine-and-alternative-and-complementary-medicine
#7
Chen-Ying Hsieh, Shou-Yu Wang, Yeu-Hui Chuang, Ho-Hsiang Chen
Stroke is ranked third among the top 10 causes of death in Taiwan. Besides a high mortality rate, stroke survivors are often left with physical or functional sequela. This study aimed to explore ischemic stroke patients' decision-making process using Western medicine (WM) and complementary and alternative medicine (CAM). This study is a qualitative study based on grounded theory. A total of 12 participants were recruited. Findings revealed that the participants accepted WM and CAM treatments following the onset of ischemic stroke...
January 2018: Holistic Nursing Practice
https://www.readbyqxmd.com/read/29205637/a-field-guide-for-cancer-diagnostics-using-cell-free-dna-from-principles-to-practice-and-clinical-applications
#8
REVIEW
Anna-Lena Volckmar, Holger Sültmann, Anja Riediger, Thoas Fioretos, Peter Schirmacher, Volker Endris, Albrecht Stenzinger, Steffen Dietz
Recently, many genome-wide profiling studies provided insights into the molecular background of major cancer types. The deeper understanding of the genetic alterations and their functional consequences leveraged the discovery of novel therapeutic opportunities, improving clinical management of cancer patients. While tissue-based molecular patient stratification is the gold standard for precision medicine, it has certain limitations: Tissue biopsies are risky invasive sampling procedures and may not represent the entire tumor due to genetic heterogeneity...
December 5, 2017: Genes, Chromosomes & Cancer
https://www.readbyqxmd.com/read/29203510/mechanisms-to-elevate-endogenous-glucagon-like-peptide-1-glp-1-beyond-injectable-glp-1-analogues-and-metabolic-surgery
#9
Daniel A Briere, Ana B Bueno, Ellen J Gunn, M Dodson Michael, Kyle W Sloop
Therapeutic engineering of glucagon-like peptide-1 (GLP-1) has enabled development of new medicines to treat type 2 diabetes mellitus. These injectable analogues achieve robust glycemic control by increasing concentrations of 'GLP-1 equivalents' (∼50 pM). Similar levels of endogenous GLP-1 occur following gastric bypass surgery, and mechanistic studies indicate glucose lowering by these procedures is driven by GLP-1. Therefore, due to the remarkable signaling and secretory capacity of the GLP-1 system, we sought to discover mechanisms that raise GLP-1 pharmacologically...
December 4, 2017: Diabetes
https://www.readbyqxmd.com/read/29198227/medical-students-attitudes-towards-participating-in-a-palliative-medicine-course-a-new-specialty-in-israel
#10
Gil Bar-Sela, Inbal Mitnik, Daniela Zalman, Ezequiel Flechter, Hedva Sheinman-Yuffe, Simon Vulfsons, Sergey Postovsky, Bella Smolin, Rachel Nave, Zaher S Azzam
BACKGROUND: Palliative medicine is a growing field in Israel, and its training program is still in process. The current study aimed to evaluate students' attitudes regarding a course in palliative care established in a division of oncology. METHOD: Some 45 medical students in their 5th to 6th years participated in a one-week course on palliative care. At the end of each training week, students were asked to complete a questionnaire, evaluating their attitudes regarding different aspects of the program content, such as its importance and relevance to their training as physicians, as well as the contribution of specific parts of the program to their knowledge regarding palliative care...
December 4, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/29198111/expansion-of-the-genetic-alphabet-a-chemist-s-approach-to-synthetic-biology
#11
Aaron W Feldman, Floyd E Romesberg
The information available to any organism is encoded in a four nucleotide, two base pair genetic code. Since its earliest days, the field of synthetic biology has endeavored to impart organisms with novel attributes and functions, and perhaps the most fundamental approach to this goal is the creation of a fifth and sixth nucleotide that pair to form a third, unnatural base pair (UBP) and thus allow for the storage and retrieval of increased information. Achieving this goal, by definition, requires synthetic chemistry to create unnatural nucleotides and a medicinal chemistry-like approach to guide their optimization...
December 2, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29197739/a-meta-analysis-of-the-use-of-probiotics-to-alleviate-depressive-symptoms
#12
REVIEW
Qin Xiang Ng, Christina Peters, Collin Yih Xian Ho, Donovan Yutong Lim, Wee-Song Yeo
INTRODUCTION: Some preclinical and clinical studies have demonstrated the positive impact of probiotic supplementation on depressive symptoms. This paper aims to provide an updated meta-analysis on the topic. METHODS: Using the keywords [probiotics OR gut OR microflora OR microbiome OR bacteria OR yeast OR yoghurt OR lactobacillus OR bifidobacterium] AND [mood OR depression OR MDD OR suicide], a preliminary search on the PubMed, Ovid, Clinical Trials Register of the Cochrane Collaboration Depression, Anxiety and Neurosis Group (CCDANTR) and Cochrane Field for Complementary Medicine database yielded 917 papers published in English between 1-Jan-1960 and 1-June-2017...
November 16, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29191190/the-effects-of-freeze-dried-ganoderma-lucidum-mycelia-on-a-recurrent-oral-ulceration-rat-model
#13
Ling Xie, Xiaohong Zhong, Dongbo Liu, Lin Liu, Zhilan Xia
BACKGROUND: Conventional scientific studies had supported the use of polysaccharides and β-glucans from a number of fungi, including Ganoderma lucidum for the treatment of recurrent oral ulceration (ROU). Our aim of the present study was to evaluate whether freeze-dried powder from G. lucidum mycelia (FDPGLM) prevents ROU in rats. METHODS: A Sprague-Dawley (SD) rat model with ROU was established by autoantigen injection. The ROU rats were treated with three different dosages of FDPGLM and prednisone acetate (PA), and their effects were evaluated according to the clinical therapeutic evaluation indices of ROU...
December 1, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29189365/using-integrative-medicine-in-pain-management-an-evaluation-of-current-evidence
#14
Yuan-Chi Lin, Limeng Wan, Robert N Jamison
Complementary medicine therapies are frequently used to treat pain conditions such as headaches and neck, back, and joint pain. Chronic pain, described as pain lasting longer than 3-6 months, can be a debilitating condition that has a significant socioeconomic impact. Pharmacologic approaches are often used for alleviating chronic pain, but recently there has been a reluctance to prescribe opioids for chronic noncancer pain because of concerns about tolerance, dependence, and addiction. As a result, there has been increased interest in integrative medicine strategies to help manage pain and to reduce reliance on prescription opioids to manage pain...
December 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29189188/complementary-alternative-and-integrative-medicine-for-childhood-atopic-dermatitis
#15
Kam Lun Hon, Alexander K C Leung, Theresa N H Leung, Vivian Leeq
Backgroud: Atopic dermatitis (AD) is a chronic relapsing dermatosis associated with itch, sleep disturbance and poor quality of life. Treatment of AD includes the use of emollients, and topical and systemic immunomodulating agents. Many patients also use complementary and alternative medicine (CAM). OBJECTIVE: This article reviews the pathophysiology of AD and clinical trials involving various modalities of CAM in the treatment of AD. METHODS: A Medline/Pubmed search was conducted using Clinical Queries with the key terms "Chinese Medicine OR Complementary and Alternative medicine" AND "Eczema OR Atopic dermatitis"...
November 28, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/29183746/assessment-of-the-anti-snakebite-properties-of-extracts-of-aniba-fragrans-ducke-lauraceae-used-in-folk-medicine-as-complementary-treatment-in-cases-of-envenomation-by-bothrops-atrox
#16
Valéria Mourão de Moura, Noranathan da Costa Guimarães, Luana Travassos Batista, Luciana A Freitas-de-Sousa, Joanderson de Sousa Martins, Maria Carolina Scheffer de Souza, Patrícia D Oliveira de Almeida, Wuelton Marcelo Monteiro, Ricardo Bezerra de Oliveira, Maria Cristina Dos-Santos, Rosa Helena Veras Mourão
ETHNOPHARMACOLOGICAL RELEVANCE: Extracts of leaves and bark of Aniba fragrans are used as tea (decoction) to treat snakebites in communities in the Brazilian Amazon. The aqueous extract of the leaves of A. fragrans has been proven to be effective against Bothrops venom, but only when pre-incubated with the venom. This study sought to assess the potential of different types of extract of this species to inhibit the biological activities of Bothrops atrox venom (BaV) when used the same way as in folk medicine...
November 25, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29178904/nutritional-supplements-and-herbal-medicines-for-women-with-polycystic-ovary-syndrome-a-systematic-review-and-meta-analysis
#17
Susan Arentz, Caroline A Smith, Jason Abbott, Alan Bensoussan
BACKGROUND: Polycystic ovary syndrome (PCOS) is a common, reproductive endocrinopathy associated with serious short and long term health risks. Many women with PCOS use ingestible complementary medicines. This systematic review examined the effect on menstrual regulation and adverse effects from randomised controlled trials. METHODS: Randomised controlled trials (RCTs) that compared herbal or nutritional supplements to placebo or active controls in women with PCOS were eligible for inclusion...
November 25, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29175699/-do-it-yourself-vaccine-rejection-and-complementary-and-alternative-medicine-cam
#18
Katie Attwell, Paul R Ward, Samantha B Meyer, Philippa J Rokkas, Julie Leask
In this article, we elucidate a symbiotic relationship between complementary and alternative medicine (CAM) and rejection of, or hesitancy towards, vaccination. In Fremantle, Western Australia, and Adelaide, South Australia, we conducted in-depth interviews from September 2013-December 2015 with 29 parents who had refused or delayed some or all of their children's vaccines. Our qualitative analysis found that for many, their do-it-yourself ethic and personal agency was enhanced by self-directed CAM use, alongside (sometimes informal) CAM practitioner instruction...
November 16, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29174791/patient-perceived-health-service-needs-in-inflammatory-arthritis-a-systematic-scoping-review
#19
REVIEW
Julian D Segan, Andrew M Briggs, Louisa Chou, Kathryn L Connelly, Maheeka Seneviwickrama, Kaye Sullivan, Flavia M Cicuttini, Anita E Wluka
BACKGROUND: Care that is patient-centred is more likely to be sustainable and associated with improved health outcomes. This approach to care requires an understanding of patients' health service needs, yet few studies have directly investigated the perceived health service needs of people with inflammatory arthritis. OBJECTIVES: To systematically identify the existing literature relating to patient perceived health service needs for inflammatory arthritis. METHODS: A systematic review of MEDLINE, EMBASE, CINAHL, and PsycINFO was conducted (1990-2016)...
October 31, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29173531/the-practical-pros-and-cons-of-complementary-and-alternative-medicine-in-practice-integrating-complementary-and-alternative-medicine-into-clinical-care
#20
REVIEW
Rachel W Winter, Joshua R Korzenik
Complementary and alternative medicine (CAM) is changing health care for individuals with inflammatory bowel disease. The move toward increasing patient autonomy and addressing lifestyle and psychosocial factors contributes to this shift. Numerous clinics and centers are offering new models to incorporate these elements. There is need for better and more robust data regarding CAM efficacy and safety. CAM offers a test kitchen for new approaches to care and care delivery, which are now being developed and studied, and has the possibility to affect patient quality of life, disease morbidity, cost, and use of health care...
December 2017: Gastroenterology Clinics of North America
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