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Audrey Long

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https://www.readbyqxmd.com/read/27930953/adolescent-binge-alcohol-exposure-increases-risk-assessment-behaviors-in-male-wistar-rats-after-exposure-to-an-acute-psychological-stressor-in-adulthood
#1
Audrey Torcaso, AnnaDorothea Asimes, Margaret Meagher, Toni R Pak
Teenage binge drinking is a common practice that has been shown to increase the risk for developing mood disorders in adulthood. The hypothalamo-pituitary-adrenal (HPA) axis is often dysfunctional in mood disorder patients, and animal models of adolescent binge alcohol exposure similarly show disordered HPA axis function, even after long periods of alcohol abstinence. Here, we sought to investigate the anxiety-like behavioral consequences of binge alcohol exposure in a Wistar rat model. Male rats were administered alcohol in a binge pattern during peri-puberty, and one month later, anxiety-like behaviors were measured using the elevated plus maze...
November 30, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27906371/depolarization-of-a-randomly-distributed-plasmonic-meander-metasurface-characterized-by-mueller-matrix-spectroscopic-ellipsometry
#2
Liwei Fu, Audrey Berrier, Huiyu Li, Philipp Schau, Karsten Frenner, Martin Dressel, Wolfgang Osten
Metallic nanostructures offer efficient solutions in polarization control with a very low thickness. In this report, we investigate the optical properties of a nano-fabricated plasmonic pseudo-depolarizer using Mueller matrix spectroscopic ellipsometry in transmission configuration. The depolarizer is composed of 256 square cells, each containing a periodically corrugated metallic film with random orientation. The full Mueller matrix was analyzed as a function of incident angle in a range between 0 and 20° and over the whole rotation angle range...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27886626/describing-clinical-faculty-experiences-with-patient-safety-and-quality-care-in-acute-care-settings-a-mixed-methods-study
#3
Linda Roney, Catherine Sumpio, Audrey M Beauvais, Eileen R O'Shea
BACKGROUND: A major safety initiative in acute care settings across the United States has been to transform hospitals into High Reliability Organizations. The initiative requires developing cognitive awareness, best practices, and infrastructure so that all healthcare providers including clinical faculty are accountable to deliver quality and safe care. OBJECTIVE: To describe the experience of baccalaureate clinical nursing faculty concerning safety and near miss events, in acute care hospital settings...
November 18, 2016: Nurse Education Today
https://www.readbyqxmd.com/read/27881140/early-signs-of-multi-walled-carbon-nanotbues-degradation-in-macrophages-via-an-intracellular-ph-dependent-biological-mechanism-importance-of-length-and-functionalization
#4
Marion Landry, Mathieu Pinault, Stéphane Tchankouo, Émeline Charon, Audrey Ridoux, Jorge Boczkowski, Martine Mayne-L'Hermite, Sophie Lanone
BACKGROUND: Carbon nanotubes (CNT) can interact with the biological environment, which could participate in their associated toxicity. We recently demonstrated that pH is an important player of CNT fate inside macrophages. We wanted to further characterize such process, and therefore designed a study dedicated to decipher CNT biodegradation by macrophages, as a function of two major physico-chemical properties in regard with nanotoxicology; length and degree of functionalization. To achieve our aim, we synthesized, following a single initial production process, four MWCNT differing in length and/or surface chemistry: S-CNT (short), SF-CNT (short functionalized), L-CNT (long) and LF-CNT (long functionalized)...
November 24, 2016: Particle and Fibre Toxicology
https://www.readbyqxmd.com/read/27870902/sleep-duration-exercise-shift-work-and-polycystic-ovarian-syndrome-related-outcomes-in-a-healthy-population-a-cross-sectional-study
#5
Audrey J R Lim, Zhongwei Huang, Seok Eng Chua, Michael S Kramer, Eu-Leong Yong
CONTEXT: Few studies have examined the associations between sleep duration, shiftwork, and exercise to the infrequent menstruation, hyperandrogenism, and ovarian morphological changes observed in women with polycystic ovarian syndrome (PCOS). OBJECTIVE: To examine whether lifestyle factors, including short sleep duration, insufficient exercise, and shiftwork, alone or in combination, are associated with the reproductive and metabolic abnormalities typical of PCOS in a healthy population...
2016: PloS One
https://www.readbyqxmd.com/read/27783195/characterization-of-the-distribution-retention-and-efficacy-of-internal-radiation-of-188-re-lipid-nanocapsules-in-an-immunocompromised-human-glioblastoma-model
#6
Annabelle Cikankowitz, Anne Clavreul, Clément Tétaud, Laurent Lemaire, Audrey Rousseau, Nicolas Lepareur, Djamel Dabli, Francis Bouchet, Emmanuel Garcion, Philippe Menei, Olivier Couturier, François Hindré
Internal radiation strategies hold great promise for glioblastoma (GB) therapy. We previously developed a nanovectorized radiotherapy that consists of lipid nanocapsules loaded with a lipophilic complex of Rhenium-188 (LNC(188)Re-SSS). This approach resulted in an 83 % cure rate in the 9L rat glioma model, showing great promise. The efficacy of LNC(188)Re-SSS treatment was optimized through the induction of a T-cell immune response in this model, as it is highly immunogenic. However, this is not representative of the human situation where T-cell suppression is usually encountered in GB patients...
October 25, 2016: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/27781378/mass-cytometry-reveals-a-distinct-immunoprofile-of-operational-tolerance-in-pediatric-liver-transplantation
#7
Audrey H Lau, Matthew J Vitalone, Kelly Haas, Todd Shawler, Carlos O Esquivel, William E Berquist, Olivia M Martinez, Ricardo O Castillo, Sheri M Krams
Long-term IS in transplant patients has significant morbidity, poorer quality of life, and substantial economic costs. TOL, defined as graft acceptance without functional impairment in the absence of IS, has been achieved in some pediatric LT recipients. Using mass cytometry, peripheral blood immunotyping was performed to characterize differences between tolerant patients and patients who are stable on single-agent IS. Single-cell mass cytometry was performed using blood samples from a single-center pediatric LT population of operationally tolerant patients to comprehensively characterize the immune cell populations in the tolerant state compared with patients on chronic low-dose IS...
October 26, 2016: Pediatric Transplantation
https://www.readbyqxmd.com/read/27778340/maternal-protein-restriction-during-gestation-and-lactation-in-the-rat-results-in-increased-brain-levels-of-kynurenine-and-kynurenic-acid-in-their-adult-offspring
#8
Paula Honório de Melo Martimiano, André de Sa Braga Oliveira, Véronique Ferchaud-Roucher, Mikaël Croyal, Audrey Aguesse, Isabelle Grit, Khadija Ouguerram, Sandra Lopes de Souza, Bertrand Kaeffer, Francisco Bolaños-Jiménez
Early malnutrition is a risk factor for depression and schizophrenia. Since the offspring of malnourished dams exhibit increased brain levels of serotonin (5-HT), a tryptophan-derived neurotransmitter involved in the pathophysiology of these mental disorders, it is believed that the deleterious effects of early malnutrition on brain function are due in large part to altered serotoninergic neurotransmission resulting from impaired tryptophan (Trp) metabolism. However, tryptophan is also metabolized through the kynurenine (KYN) pathway yielding several neuroactive compounds including kynurenic (KA), Qinolinic (QA) and Xanthurenic (XA) acids...
October 25, 2016: Journal of Neurochemistry
https://www.readbyqxmd.com/read/27775458/efficacy-of-anti-tnf-%C3%AE-therapy-for-the-treatment-of-non-infectious-uveitis-a-retrospective-study-of-21-patients
#9
Audrey-Elodie Mercier, Emmanuel Ribeiro, Jean-François Korobelnik, Marie-Noëlle Delyfer, Marie-Bénédicte Rougier
PURPOSE: To assess the efficacy of anti-TNF alpha (TNF-α) therapy in patients with non-infectious uveitis. METHODS: This was a monocentric observational study of 21 patients with non-infectious uveitis treated with anti-TNF-alpha. The primary endpoint was the control of ocular inflammation. The secondary endpoints included the study of macular thickness and visual acuity, changes in other treatments, and adverse effects. RESULTS: The etiologies of uveitis were Behçet disease (33...
October 24, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27768103/peptide-tessellation-yields-micrometre-scale-collagen-triple-helices
#10
I Caglar Tanrikulu, Audrey Forticaux, Song Jin, Ronald T Raines
Sticky-ended DNA duplexes can associate spontaneously into long double helices; however, such self-assembly is much less developed with proteins. Collagen is the most prevalent component of the extracellular matrix and a common clinical biomaterial. As for natural DNA, the ~10(3)-residue triple helices (~300 nm) of natural collagen are recalcitrant to chemical synthesis. Here we show how the self-assembly of short collagen-mimetic peptides (CMPs) can enable the fabrication of synthetic collagen triple helices that are nearly a micrometre in length...
November 2016: Nature Chemistry
https://www.readbyqxmd.com/read/27757228/telehealth-acceptability-clinical-interventions-and-quality-of-life-in-peritoneal-dialysis
#11
Vishal Dey, Audrey Jones, Elaine M Spalding
INTRODUCTION: Telehealth technologies are being widely adopted across the globe for management of long-term conditions. There are limited data on its use, effectiveness and patient experience in end-stage renal disease. The aim of this pilot project was to explore patient acceptability of technology and evaluate its effect on clinical interventions and quality of life in patients undergoing peritoneal dialysis. METHODS: Peritoneal dialysis patients were provided with computer tablets (PODs)...
2016: SAGE Open Medicine
https://www.readbyqxmd.com/read/27753458/anticipatory-eye-movements-and-long-term-memory-in-early-infancy
#12
Audrey M B Wong-Kee-You, Scott A Adler
Advances in our understanding of long-term memory in early infancy have been made possible by studies that have used the Rovee-Collier's mobile conjugate reinforcement paradigm and its variants. One function that has been attributed to long-term memory is the formation of expectations (Rovee-Collier & Hayne, 1987); consequently, a long-term memory representation should be established during expectation formation. To examine this prediction and potentially open the door on a new paradigm for exploring infants' long-term memory, using the Visual Expectation Paradigm (Haith, Hazan, & Goodman, 1988), 3-month-old infants were trained to form an expectation for predictable color and spatial information of picture events and emit anticipatory eye movements to those events...
November 2016: Developmental Psychobiology
https://www.readbyqxmd.com/read/27741391/effects-of-ph-electrolyte-humic-acid-and-light-exposure-on-the-long-term-fate-of-silver-nanoparticles
#13
Wei Zhou, Yen-Ling Liu, Audrey M Stallworth, Chunsong Ye, John J Lenhart
We investigated the evolution in silver nanoparticle (AgNP) properties during a series of 10 - 50 day experiments on suspensions with different pH (5 - 9), electrolyte type (NaNO3 and NaCl) and concentration (2 mM and 6 mM), Suwanee River humic acid (SRHA) concentration (0 - 13.2 mg C/L) and light exposure (artificial sun light exposure for 8h per day or dark). Of these factors, pH most influenced the AgNPs' properties as it modifies surface charge as well as AgNP dissolution and oxidation, and Ag+ reduction reactions...
October 14, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27734111/reliability-of-a-ct-reconstruction-for-preoperative-surgical-planning-in-the-arthroscopic-latarjet-procedure
#14
Alexandre Hardy, Philippe Loriaut, Benjamin Granger, Ahmed Neffati, Audrey Massein, Laurent Casabianca, Hugues Pascal-Moussellard, Antoine Gerometta
PURPOSE: The arthroscopic Latarjet procedure has provided reliable results in the treatment of anterior shoulder instability. However, this procedure remains technically challenging and is related to several complications. The morphology of the coracoid and the glenoid are inconsistent. Inadequate coracoid and glenoid preparing may lead to mismatching between their surfaces. Inadequate screws lengthening and orientation are a major concern. Too long screws can lead to suprascapular nerve injuries or hardware irritation, whereas too short screws can lead to nonunions, fibrous unions or migration of the bone block...
October 12, 2016: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/27723273/frequency-and-duration-of-adrenal-suppression-following-glucocorticoid-therapy-in-children-with-rheumatic-diseases
#15
Alexandra Ahmet, Vincent Brienza, Audrey Tran, Julie Lemieux, Mary Aglipay, Nick Barrowman, Ciaran Duffy, Johannes Roth, Roman Jurencak
OBJECTIVE: Adrenal suppression (AS), a glucocorticoid (GC) side effect with potentially significant morbidity, is poorly understood. The purpose of our study was to determine frequency, duration and predictors of AS following a gradual taper of GC in children with rheumatologic conditions. METHODS: Prospective observational cohort study was conducted. All patients ≤16 years ready to discontinue GC after >4weeks of therapy were included. Morning cortisol was tested 4 weeks after GC taper to physiologic doses and then repeatedly until normalization...
October 9, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27703033/video-only-cardiopulmonary-resuscitation-education-for-high-risk-families-before-hospital-discharge-a-multicenter-pragmatic-trial
#16
Audrey L Blewer, Mary E Putt, Lance B Becker, Barbara J Riegel, Jiaqi Li, Marion Leary, Judy A Shea, James N Kirkpatrick, Robert A Berg, Vinay M Nadkarni, Peter W Groeneveld, Benjamin S Abella
BACKGROUND: Cardiopulmonary resuscitation (CPR) training rates in the United States are low, highlighting the need to develop CPR educational approaches that are simpler, with broader dissemination potential. The minimum training required to ensure long-term skill retention remains poorly characterized. We compared CPR skill retention among laypersons randomized to training with video-only (VO; no manikin) with those trained with a video self-instruction kit (VSI; with manikin). We hypothesized that VO training would be noninferior to the VSI approach with respect to chest compression (CC) rate...
October 4, 2016: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/27678342/the-effectiveness-acceptability-and-cost-effectiveness-of-psychosocial-interventions-for-maltreated-children-and-adolescents-an-evidence-synthesis
#17
REVIEW
Geraldine Macdonald, Nuala Livingstone, Jennifer Hanratty, Claire McCartan, Richard Cotmore, Maria Cary, Danya Glaser, Sarah Byford, Nicky J Welton, Tania Bosqui, Lucy Bowes, Suzanne Audrey, Gill Mezey, Helen L Fisher, Wendy Riches, Rachel Churchill
BACKGROUND: Child maltreatment is a substantial social problem that affects large numbers of children and young people in the UK, resulting in a range of significant short- and long-term psychosocial problems. OBJECTIVES: To synthesise evidence of the effectiveness, cost-effectiveness and acceptability of interventions addressing the adverse consequences of child maltreatment. STUDY DESIGN: For effectiveness, we included any controlled study...
September 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27659598/body-mass-index-and-total-psoas-area-affect-outcomes-in-patients-undergoing-pneumonectomy-for-cancer
#18
Remi Hervochon, Antonio Bobbio, Claude Guinet, Audrey Mansuet-Lupo, Antoine Rabbat, Jean-François Régnard, Nicolas Roche, Diane Damotte, Antonio Iannelli, Marco Alifano
BACKGROUND: Hypothesizing that morphometric measurements are reliable markers of fitness in patients with lung cancer requiring aggressive surgical intervention, the purpose of this study was to assess their impact on postoperative outcome and long-term survival in patients with non-small cell lung cancer (NSCLC) requiring pneumonectomy. METHODS: Height, weight, and body mass index (BMI), as well as usual clinical, laboratory (including C-reactive protein [CRP] concentrations), and pathologic data were retrospectively retrieved from files of 161 consecutive patients treated by pneumonectomy for NSCLC, whose preoperative computed tomographic (CT) scans were available in the Picture Archive and Communication System (PACS) of the hospital...
September 19, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27631173/endothelial-pattern-formation-in-hybrid-constructs-of-additive-manufactured-porous-rigid-scaffolds-and-cell-laden-hydrogels-for-orthopedic-applications
#19
Yaser Shanjani, Yunqing Kang, Livia Zarnescu, Audrey K Ellerbee Bowden, Jeong-Tae Koh, Dai Fei Elmer Ker, Yunzhi Yang
Vascularization of tissue engineering constructs (TECs) in vitro is of critical importance for ensuring effective and satisfactory clinical outcomes upon implantation of TECs. Biomechanical properties of TECs have remarkable influence on the in vitro vascularization of TECs. This work utilized in vitro experiments and finite element analysis to investigate endothelial patterns in hybrid constructs of soft collagen gels and rigid macroporous poly(ε-caprolactone)-β-tricalcium phosphate (PCL-β-TCP) scaffold seeded/embedded with human umbilical vein endothelial cells (HUVECs) for bone tissue engineering applications...
September 4, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27621554/fabrication-of-new-restorations-with-a-consideration-of-oral-hygiene
#20
Swati Ahuja, Russell Wicks, Audrey Selecman
Maintenance of adequate and effective oral hygiene is crucial for the long-term success of any dental therapy. This article discusses a case that failed due to the poor oral hygiene of the patient. Fabrication of uncomplicated restorations, patient education, motivation, maintenance and recall are important factors to be considered when treatment planning patients with poor oral hygiene.
July 2016: Journal of Indian Prosthodontic Society
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