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Joanna moncrieff

SebastiĆ£o Viola, Joanna Moncrieff
BACKGROUND: There is international concern about the levels of sickness and disability benefits, with mental disorders known to account for a large proportion of claims. AIMS: To examine trends in sickness and disability benefits awarded for mental disorders in the UK. METHOD: The researchers analysed UK Government data from 1995 to 2014. RESULTS: Mental disorders have become the most common cause of receiving benefits, with the number of claimants rising by 103% from 1995 to 1...
January 2016: BJPsych Open
Joanna Moncrieff, Kiran Azam, Sonia Johnson, Louise Marston, Nicola Morant, Katherine Darton, Neil Wood
BACKGROUND: Government policy encourages increasing involvement of patients in their long-term care. This paper describes the development and pilot evaluation of a 'Medication Review Tool' designed to assist people to participate more effectively in discussions about antipsychotic drug treatment. METHODS: The Medication Review Tool developed consisted of a form to help patients identify pros and cons of their current antipsychotic treatment and any desired changes...
2016: BMC Psychiatry
Joanna Moncrieff
No abstract text is available yet for this article.
2016: BMJ: British Medical Journal
Joanna Moncrieff
No abstract text is available yet for this article.
October 2015: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)
Joanna Moncrieff
Joanna Moncrieff looks at the lack of long-term evidence for antipsychotic medication and considers what is needed to ensure we have the knowledge to maximize benefits and minimize harms.
August 2015: PLoS Medicine
Mauricio Silva de Lima, Joanna Moncrieff, Bernardo G O Soares
No abstract text is available yet for this article.
2015: Cochrane Database of Systematic Reviews
Joanna Moncrieff, Irving Kirsch
Meta-analyses indicate that antidepressants are superior to placebos in statistical terms, but the clinical relevance of the differences has not been established. Previous suggestions of clinically relevant effect sizes have not been supported by empirical evidence. In the current paper we apply an empirical method that consists of comparing scores obtained on the Hamilton rating scale for depression (HAM-D) and scores from the Clinical Global Impressions-Improvement (CGI-I) scale. This method reveals that a HAM-D difference of 3 points is undetectable by clinicians using the CGI-I scale...
July 2015: Contemporary Clinical Trials
Paul Hutton, Peter J Taylor, Lee Mulligan, Sarah Tully, Joanna Moncrieff
BACKGROUND: Immediate-release (IR) quetiapine has been used to treat schizophrenia since 1997, although all the principal placebo-controlled trials have >50% missing outcome data. New studies with relatively lower rates of participant withdrawal have since been published. AIMS: To assess the efficacy and adverse effects of quetiapine IR for schizophrenia, with consideration of outcome quality and clinical meaningfulness of results, and to examine the potential impact of missing data on the main efficacy findings...
May 2015: British Journal of Psychiatry: the Journal of Mental Science
Joanna Moncrieff, Hugh Middleton
PURPOSE OF REVIEW: The term 'schizophrenia' has been hotly contested over recent years. The current review explores the meanings of the term, whether it is valid and helpful and how alternative conceptions of severe mental disturbance would shape clinical practice. RECENT FINDINGS: Schizophrenia is a label that implies the presence of a biological disease, but no specific bodily disorder has been demonstrated, and the language of 'illness' and 'disease' is ill-suited to the complexities of mental health problems...
May 2015: Current Opinion in Psychiatry
Joanna Moncrieff
The concept of bipolar disorder has undergone a transformation over the last two decades. Once considered a rare and serious mental disorder, bipolar disorder is being diagnosed with increasing frequency in Europe and North America, and is suggested to replace many other diagnoses. The current article shows how the modern concept of bipolar disorder has been created in the course of efforts to market new antipsychotics and other drugs for bipolar disorder, to enable these drugs to migrate out of the arena of serious mental disorder and into the more profitable realm of everyday emotional problems...
August 2014: Transcultural Psychiatry
Laura Allison, Joanna Moncrieff
This paper examines factors involved in the theory and practice of emergency sedation for behavioural disturbance in psychiatry in the mid-twentieth century, and the emergence of the concept of 'rapid tranquillisation'. The practice received little attention until the arrival of antipsychotic drugs, which replaced older sedatives and became the agents most strongly associated with the treatment of aggression and challenging behaviour. Emergency sedation was subsequently portrayed in psychiatric literature and advertising as a therapeutic and diagnosis-driven endeavour, and the concept of rapid tranquillisation emerged in this context in the 1970s...
March 2014: History of Psychiatry
Joanna Moncrieff, David Cohen, Sally Porter
The psychoactive effects of psychiatric medications have been obscured by the presumption that these medications have disease-specific actions. Exploiting the parallels with the psychoactive effects and uses of recreational substances helps to highlight the psychoactive properties of psychiatric medications and their impact on people with psychiatric problems. We discuss how psychoactive effects produced by different drugs prescribed in psychiatric practice might modify various disturbing and distressing symptoms, and we also consider the costs of these psychoactive effects on the mental well-being of the user...
November 2013: Journal of Psychoactive Drugs
Stuart Watson, Peter Gallagher, Dominic Dougall, Richard Porter, Joanna Moncrieff, I Nicol Ferrier, Allan H Young
OBJECTIVE: There has been little investigation of early trauma in bipolar disorder despite evidence that stress impacts on the course of this illness. We aimed to compare the rates of childhood trauma in adults with bipolar disorder to a healthy control group, and to investigate the impact of childhood trauma on the clinical course of bipolar disorder. METHODS: Retrospective assessment of childhood trauma was conducted using the Childhood Trauma Questionnaire (CTQ) in 60 outpatients with bipolar disorder being treated for a depressive episode and 55 control participants across two centres in north-east England and New Zealand...
June 2014: Australian and New Zealand Journal of Psychiatry
Joanna Moncrieff, Sami Timimi
The current paper presents an analysis of the NICE guidelines on depression and attention deficit hyperactivity disorder (ADHD) from the perspective of the philosophy of science, guided particularly by Foucault's notion of the symbiosis of knowledge and power. It examines how data that challenged the orthodox position on the validity and drug treatment of these conditions was managed in the process of guideline development. The depression guideline briefly considered the complexity and heterogeneity of depression, and numerous methodological problems with evaluating treatments, including antidepressants...
April 2013: Anthropology & Medicine
Joanna Moncrieff
When "antipsychotic" drugs were introduced into psychiatry in the 1950s, they were thought to work by inducing a state of neurological suppression, which reduced behavioral disturbance as well as psychotic symptoms. This view was reflected in the name "neuroleptic." Within a few years, however, the idea that the drugs were a disease-specific treatment for schizophrenia or psychosis, and that they worked by modifying the underlying pathology of the condition, replaced this earlier view, and they became known as "antipsychotics...
2013: Journal of the History of the Neurosciences
Pat Bracken, Philip Thomas, Sami Timimi, Eia Asen, Graham Behr, Carl Beuster, Seth Bhunnoo, Ivor Browne, Navjyoat Chhina, Duncan Double, Simon Downer, Chris Evans, Suman Fernando, Malcolm R Garland, William Hopkins, Rhodri Huws, Bob Johnson, Brian Martindale, Hugh Middleton, Daniel Moldavsky, Joanna Moncrieff, Simon Mullins, Julia Nelki, Matteo Pizzo, James Rodger, Marcellino Smyth, Derek Summerfield, Jeremy Wallace, David Yeomans
A series of editorials in this Journal have argued that psychiatry is in the midst of a crisis. The various solutions proposed would all involve a strengthening of psychiatry's identity as essentially 'applied neuroscience'. Although not discounting the importance of the brain sciences and psychopharmacology, we argue that psychiatry needs to move beyond the dominance of the current, technological paradigm. This would be more in keeping with the evidence about how positive outcomes are achieved and could also serve to foster more meaningful collaboration with the growing service user movement...
December 2012: British Journal of Psychiatry: the Journal of Mental Science
Peter Kinderman, John Read, Joanna Moncrieff, Richard P Bentall
No abstract text is available yet for this article.
February 2013: Evidence-based Mental Health
Stephen Ilyas, Joanna Moncrieff
BACKGROUND: Increasing rates of prescriptions for antidepressants, antipsychotics and stimulants have been reported from various countries. AIMS: To examine trends in prescriptions and the costs of all classes of psychiatric medication in England. METHOD: Data from the Prescription Cost Analysis 1998-2010 was examined, using linear regression analysis to examine trends. RESULTS: Prescriptions of drugs used for mental disorders increased by 6...
May 2012: British Journal of Psychiatry: the Journal of Mental Science
Hugh Middleton, Joanna Moncrieff
Despite NICE guidance that should have limited it, antidepressant prescribing continues to increase. Research evidence suggests that much if not all of the observed efficacy should be attributed to complex non-specific effects rather than 'restoration of disturbed brain chemistry'. According to this view the uncertain benefits of antidepressants are unlikely to outweigh the risks, suggesting the need to explore other approaches to treatment.
January 2011: British Journal of General Practice: the Journal of the Royal College of General Practitioners
Lucy Goldsmith, Joanna Moncrieff
Although antidepressants are known to produce some adverse mental effects, their full range of psychoactive effects has not been systematically described. It has been suggested that some antidepressants are associated with increased suicidal thoughts and actions, but the issue remains controversial, and the mechanism of association, if any, is unclear. In the current study we examined descriptions of the major psychoactive and physical effects experienced by users of two commonly used antidepressants, fluoxetine and venlafaxine, as reported on a patient-oriented web site...
April 2011: Current Drug Safety
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