Gian Maria Busetto, Bernarde F Rodrigues, Ashraf Virmani, Andrea Checchia, Antonella Ninivaggi, Anna Ricapito, Giovanni Barbieri, Piero Fischetti, Ugo G Falagario, Pasquale Annese, Nicola d'Altilia, Vito Mancini, Matteo Ferro, Felice Crocetto, Angelo Porreca, Carlo Bettocchi, Luigi Cormio, Ashok Agarwal, Giuseppe Carrieri
Oxidative stress is one of the main mechanisms responsible for male infertility. Various conditions such as varicocele, obesity, advanced age, and lifestyle can lead to an increase in reactive oxygen species, causing an oxidative imbalance in the reproductive environment. Spermatozoa are sensitive to reactive oxygen species and require energy to carry out their main function of fertilizing the egg. Excessive reactive oxygen species can affect sperm metabolism, leading to immobility, impaired acrosome reaction, and cell death, thereby impairing reproductive success...
February 2, 2024: Asian Journal of Andrology