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https://www.readbyqxmd.com/read/27918928/effect-of-a-grazing-period-prior-to-finishing-on-a-high-concentrate-diet-on-meat-quality-from-bulls-and-steers
#1
L Moran, M G O'Sullivan, J P Kerry, B Picard, M McGee, E G O'Riordan, A P Moloney
Bulls and steers (n=60) were assigned to a pre-finishing grazing period and subsequently finished on concentrates or offered concentrates without grazing until slaughter (19months). Colour and pH of longissimus thoracis were measured (48h post-slaughter), and samples collected for proximate composition, collagen, sarcomere length, muscle fibre and enzymatic profile analysis. Steaks for texture, cook loss and sensory were aged (14days). Castration increased intramuscular fat content, cook loss and myosin isoforms IIa and I proportions, and decreased IIx proportion (P<0...
November 29, 2016: Meat Science
https://www.readbyqxmd.com/read/27916591/heart-failure-hospitalisations-in-the-hunter-new-england-area-over-10-years-a-changing-trend
#2
Mohammed S Al-Omary, Allan J Davies, Arshad A Khan, Michael McGee, Bruce Bastian, James Leitch, John Attia, Peter J Fletcher, Andrew J Boyle
BACKGROUND: Heart failure carries a major burden on our health system, mainly related to the high rate of hospital admission. An understanding of the recent trends in heart failure hospitalisation is essential to the future allocation of health resources. Our aim is to analyse the temporal trends in heart failure hospitalisation. METHODS: We extracted all separations in the Hunter New England Local Health District between 2005-2014 (n=40,119) with an ICD 10 code for heart failure (I-50) in the first four diagnoses on discharge...
November 19, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27914496/computed-tomography-derived-skeletal-muscle-index-a-novel-predictor-of-frailty-and-hospital-length-of-stay-after-transcatheter-aortic-valve-replacement
#3
Vishal Dahya, Jingjie Xiao, Carla M Prado, Penny Burroughs, Dan McGee, Aline C Silva, Julian E Hurt, Shafi G Mohamed, Thomas Noel, Wayne Batchelor
: To determine the prevalence of low skeletal muscle mass in patients undergoing transcatheter aortic valve replacement (TAVR) and whether skeletal muscle mass measured from preoperative computed tomography (CT) images provides value in predicting postoperative length of stay (LOS). BACKGROUND: There are limited data on the use of body composition as a frailty measure in TAVR patients and no studies have determined if this measure predicts LOS. METHODS: We studied 104 consecutive patients who underwent TAVR at Tallahassee Memorial Hospital from 2012 to 2016...
December 2016: American Heart Journal
https://www.readbyqxmd.com/read/27913494/introduction-to-cancer-genetic-susceptibility-syndromes
#4
Rose B McGee, Kim E Nichols
The last 30 years have witnessed tremendous advances in our understanding of the cancer genetic susceptibility syndromes, including those that predispose to hematopoietic malignancies. The identification and characterization of families affected by these syndromes is enhancing our knowledge of the oncologic and nononcologic manifestations associated with predisposing germ line mutations and providing insights into the underlying disease mechanisms. Here, we provide an overview of the cancer genetic susceptibility syndromes, focusing on aspects relevant to the evaluation of patients with leukemia and lymphoma...
December 2, 2016: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/27911963/teaching-evidence-based-physical-diagnosis-six-bedside-lessons
#5
Steven McGee
Evidence-based physical diagnosis is an essential part of the bedside curriculum. By using the likelihood ratio, a simple measure of diagnostic accuracy, teachers can quickly adapt this approach to their bedside teaching. Six recurring themes in evidence-based physical diagnosis are fully reviewed, with examples, in this article.
December 2016: Southern Medical Journal
https://www.readbyqxmd.com/read/27881532/genome-sequence-of-mycobacteriophage-erniej
#6
Courtney J Robinson, Laricca Y London-Thomas, Leon A Dickson, Tiffany A Clinton, Hana Baig, Maude Bute, Mohammed Fahad, Kanhai Farrakhan, Neshaun Grady, Nicholas E Guthrie, Ruoa Hafid, Jayla Harvey, Kellie Hunnicutt, Victoria L Larsen, Taashaylaray McDuffie, Earyn N McGee, Jillian Y Pailin, Bria Peacock, Antolice Thomas, Winston A Anderson
ErnieJ, a cluster C mycobacteriophage that infects Mycobacterium smegmatis mc(2)155, was recovered from soil in Washington, DC. Its genome is 153,243 bp in size and encodes 227 predicted proteins, 30 tRNAs, and one transfer-messenger RNA (tmRNA). Ten percent of the predicted proteins have homologs in phages that infect nonmycobacterial Actinobacteria.
November 23, 2016: Genome Announcements
https://www.readbyqxmd.com/read/27865490/effect-of-concentrate-supplementation-during-the-dry-period-on-colostrum-quality-and-effect-of-colostrum-feeding-regimen-on-passive-transfer-of-immunity-calf-health-and-performance
#7
A Dunn, A Ashfield, B Earley, M Welsh, A Gordon, M McGee, S J Morrison
The objectives were to evaluate the effect of (1) supplementing concentrates to multiparous Holstein cows during the dry period on colostral and milk immunoglobulin G (IgG) concentration; and (2) feeding calves colostrum at either 5 or 10% of their body weight (BW) on passive transfer of immunity, health, and performance. Holstein multiparous cows (n = 37) were assigned to 1 of 2 nutritional treatments during an 8-wk dry period: (1) offered ad libitum grass silage only (GS) or (2) offered ad libitum access to the same grass silage plus concentrate [total mixed ration in a 75:25 dry matter (DM) ratio], providing a mean concentrate DM intake of 3...
November 16, 2016: Journal of Dairy Science
https://www.readbyqxmd.com/read/27864935/adenoid-cystic-carcinoma-of-the-trachea-resulting-in-fatal-asphyxia
#8
Butch Huston, Victor Froloff, Kelly Mills, Michael McGee
Primary malignant tumors of the trachea are uncommon. The authors report a case of a 72-year-old female who died from asphyxia due to an undiagnosed obstructing adenoid cystic carcinoma of the trachea. The decedent became unresponsive while eating cereal and was pronounced upon arrival at the local hospital. The autopsy revealed a near occlusive tumor mass just superior to the bifurcation of the distal trachea. There was no evidence of aspiration. The death was the result of asphyxia due to obstruction of the trachea by an adenoid cystic carcinoma...
November 16, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27863363/exercise-based-cardiac-rehabilitation-in-twelve-european-countries-results-of-the-european-cardiac-rehabilitation-registry
#9
Werner Benzer, Bernhard Rauch, Jean-Paul Schmid, Ann Dorthe Zwisler, Paul Dendale, Constantinos H Davos, Evangelia Koudi, Attila Simon, Ana Abreu, Nana Pogosova, Dan Gaita, Bojan Miletic, Gerd Bönner, Taoufik Ouarrak, Hannah McGee
AIM: Results from EuroCaReD study should serve as a benchmark to improve guideline adherence and treatment quality of cardiac rehabilitation (CR) in Europe. METHODS AND RESULTS: Data from 2.054 CR patients in 12 European countries were derived from 69 centres. 76% were male. Indication for CR differed between countries being predominantly ACS in Switzerland (79%), Portugal (62%) and Germany (61%), elective PCI in Greece (37%), Austria (36%) and Spain (32%), and CABG in Croatia and Russia (36%)...
November 11, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27850214/574-extreme-body-mass-indices-are-associated-with-greater-mortality-in-patients-with-c-diff-infections
#10
William McGee, Brian Nathanson, Thomas Higgins
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27832151/nationwide-trends-in-bacterial-meningitis-before-the-introduction-of-13-valent-pneumococcal-conjugate-vaccine-burkina-faso-2011-2013
#11
Dinanibè Kambiré, Heidi M Soeters, Rasmata Ouédraogo-Traoré, Isaïe Medah, Lassana Sangare, Issaka Yaméogo, Guetawendé Sawadogo, Abdoul-Salam Ouédraogo, Soumeya Hema-Ouangraoua, Lesley McGee, Velusamy Srinivasan, Flavien Aké, Malika Congo-Ouédraogo, Soufian Sanou, Absatou Ky Ba, Ryan T Novak, Chris Van Beneden
BACKGROUND: Following introduction of Haemophilus influenzae type b vaccine in 2006 and serogroup A meningococcal conjugate vaccine in 2010, Streptococcus pneumoniae (Sp) became the leading cause of bacterial meningitis in Burkina Faso. We describe bacterial meningitis epidemiology, focusing on pneumococcal meningitis, before 13-valent pneumococcal conjugate vaccine (PCV13) introduction in the pediatric routine immunization program in October 2013. METHODS: Nationwide population-based meningitis surveillance collects case-level demographic and clinical information and cerebrospinal fluid (CSF) laboratory results...
2016: PloS One
https://www.readbyqxmd.com/read/27828955/correction-directed-evolution-reveals-unexpected-epistatic-interactions-that-alter-metabolic-regulation-and-enable-anaerobic-xylose-use-by-saccharomyces-cerevisiae
#12
Trey K Sato, Mary Tremaine, Lucas S Parreiras, Alexander S Hebert, Kevin S Myers, Alan J Higbee, Maria Sardi, Sean J McIlwain, Irene M Ong, Rebecca J Breuer, Ragothaman Avanasi Narasimhan, Mick A McGee, Quinn Dickinson, Alex La Reau, Dan Xie, Mingyuan Tian, Jeff S Piotrowski, Jennifer L Reed, Yaoping Zhang, Joshua J Coon, Chris Todd Hittinger, Audrey P Gasch, Robert Landick
[This corrects the article DOI: 10.1371/journal.pgen.1006372.].
November 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27824537/breaking-the-pain-contract-a-better-controlled-substance-agreement-for-patients-on-chronic-opioid-therapy
#13
REVIEW
Daniel G Tobin, Kristine Keough Forte, Summer Johnson McGee
"Pain contracts" for patients receiving long-term opioid therapy, though well-intentioned, often stigmatize the patient and erode trust between patient and physician. This article discusses how to improve these agreements to promote adherence, safety, trust, and shared decision-making.
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27821148/understanding-pneumococcal-serotype-1-biology-through-population-genomic-analysis
#14
Chrispin Chaguza, Jennifer E Cornick, Simon R Harris, Cheryl P Andam, Laura Bricio-Moreno, Marie Yang, Feyruz Yalcin, Sani Ousmane, Shanil Govindpersad, Madikay Senghore, Chinelo Ebruke, Mignon Du Plessis, Anmol M Kiran, Gerd Pluschke, Betuel Sigauque, Lesley McGee, Keith P Klugman, Paul Turner, Jukka Corander, Julian Parkhill, Jean-Marc Collard, Martin Antonio, Anne von Gottberg, Robert S Heyderman, Neil French, Aras Kadioglu, William P Hanage, Dean B Everett, Stephen D Bentley
BACKGROUND: Pneumococcus kills over one million children annually and over 90 % of these deaths occur in low-income countries especially in Sub-Saharan Africa (SSA) where HIV exacerbates the disease burden. In SSA, serotype 1 pneumococci particularly the endemic ST217 clone, causes majority of the pneumococcal disease burden. To understand the evolution of the virulent ST217 clone, we analysed ST217 whole genomes from isolates sampled from African and Asian countries. METHODS: We analysed 226 whole genome sequences from the ST217 lineage sampled from 9 African and 4 Asian countries...
November 8, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27815958/coracoid-fracture-following-latarjet-failure-a-case-report
#15
Brian Capogna, William E Ryan, Alan W McGee, Laith M Jazrawi
The Latarjet procedure involves the transfer of the coracoid process with its soft tissue attachments, thereby providing both bony and soft tissue articular reinforcement for glenohumeral stabilization. Most studies show positive outcomes with this procedure and complications at rates as low as 1%, predominately secondary to technical error. We present a case of recurrent anterior instability after two attempts at soft tissue stabilization (arthroscopic labral repair followed by open inferior capsular shift) in which an open Latarjet procedure was performed followed by subsequent revision secondary to coracoid autograft fracture...
November 2016: Bulletin of the Hospital for Joint Diseases
https://www.readbyqxmd.com/read/27814245/effects-of-periconception-cadmium-and-mercury-co-administration-to-mice-on-indices-of-chronic-disease-in-male-offspring-at-maturity
#16
Cagri Camsari, Joseph K Folger, Devin McGee, Steven J Bursian, Hongbing Wang, Jason G Knott, George W Smith
BACKGROUND: Long-term exposure to the heavy metals cadmium (Cd) and mercury (Hg) is known to increase risk of chronic diseases. However, to our knowledge, exposure to Cd and Hg beginning at the periconception period has not been studied to date. OBJECTIVE: The effect of co-administration of Cd and Hg during early development on indices of chronic diseases at adulthood was examined. METHODS: Adult female CD1 mice were subcutaneously administered a combination of cadmium chloride (CdCl2) and methylmercury (II) chloride (CH3HgCl; 0, 0...
November 4, 2016: Environmental Health Perspectives
https://www.readbyqxmd.com/read/27803363/death-permanence-and-current-practice-in-donation-after-circulatory-death
#17
REVIEW
Dale Gardiner, Andrew McGee
No abstract text is available yet for this article.
November 1, 2016: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/27798181/nogo-receptor-1-confines-a-disinhibitory-microcircuit-to-the-critical-period-in-visual-cortex
#18
Céleste-Élise Stephany, Taruna Ikrar, Collins Nguyen, Xiangmin Xu, Aaron W McGee
: A characteristic of the developing mammalian visual system is a brief interval of plasticity, termed the "critical period," when the circuitry of primary visual cortex is most sensitive to perturbation of visual experience. Depriving one eye of vision (monocular deprivation [MD]) during the critical period alters ocular dominance (OD) by shifting the responsiveness of neurons in visual cortex to favor the nondeprived eye. A disinhibitory microcircuit involving parvalbumin-expressing (PV) interneurons initiates this OD plasticity...
October 26, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27784800/consolidation-of-visuomotor-adaptation-memory-with-consistent-and-noisy-environments
#19
Rodrigo S Maeda, Steven E McGee, Daniel S Marigold
Our understanding of how we learn and retain motor behaviors is still limited. For instance, there is conflicting evidence as to whether the memory of a learned visuomotor perturbation consolidates; that is, the motor memory becomes resistant to interference from learning a competing perturbation over time. Here, we sought to determine the factors that influence consolidation during visually guided walking. Subjects learned a novel mapping relationship, created by prism lenses, between the perceived location of two targets and the motor commands necessary to direct the feet to their positions...
October 26, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27758858/enhancer-of-zeste-homolog-2-inhibition-stimulates-bone-formation-and-mitigates-bone-loss-caused-by-ovariectomy-in-skeletally-mature-mice
#20
Amel Dudakovic, Emily T Camilleri, Scott M Riester, Christopher R Paradise, Martina Gluscevic, Thomas M O'Toole, Roman Thaler, Jared M Evans, Huihuang Yan, Malayannan Subramaniam, John R Hawse, Gary S Stein, Martin A Montecino, Meghan E McGee-Lawrence, Jennifer J Westendorf, Andre J van Wijnen
Perturbations in skeletal development and bone degeneration may result in reduced bone mass and quality, leading to greater fracture risk. Bone loss is mitigated by bone protective therapies, but there is a clinical need for new bone-anabolic agents. Previous work has demonstrated that Ezh2 (enhancer of zeste homolog 2), a histone 3 lysine 27 (H3K27) methyltransferase, suppressed differentiation of osteogenic progenitors. Here, we investigated whether inhibition of Ezh2 can be leveraged for bone stimulatory applications...
November 18, 2016: Journal of Biological Chemistry
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