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https://www.readbyqxmd.com/read/29771356/versatility-of-dorsal-metacarpal-artery-flaps-for-hand-burns
#1
Jennel M Carreras, Catherine McGee, Faisal Al-Mufarrej
Burns to the hands can be devastating injuries and early debridement and coverage can prevent these chronic problems. Reconstructive options for these defects include skin grafts, local, regional and distant flaps as well as free flaps. In this series we set out to demonstrate the versatility, durability and effectiveness of dorsal metacarpal artery flaps for primary soft tissue coverage This study involves a review of all consecutive patients who underwent acute soft tissue coverage using dorsal metacarpal artery flaps at our institution from December 2014 to December 2017...
May 16, 2018: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/29768445/nogo-receptor-1-is-expressed-by-nearly-all-retinal-ganglion-cells
#2
Alexander M Solomon, Teleza Westbrook, Greg D Field, Aaron W McGee
A variety of conditions ranging from glaucoma to blunt force trauma lead to optic nerve atrophy. Identifying signaling pathways for stimulating axon growth in the optic nerve may lead to treatments for these pathologies. Inhibiting signaling by the nogo-66 receptor 1 (NgR1) promotes the re-extension of axons following a crush injury to the optic nerve, and while NgR1 mRNA and protein expression are observed in the retinal ganglion cell (RGC) layer and inner nuclear layer, which retinal cell types express NgR1 remains unknown...
2018: PloS One
https://www.readbyqxmd.com/read/29763977/transforming-care-to-evidence-based-practice-with-scripted-messages-an-improvement-project-for-pain-management-in-outpatient-surgical-patients
#3
Lanell M Bellury, Karen Mullinax, Judi Mozingo, Berta Dantzler, Nancy McGee
BACKGROUND: Outpatient surgeries are common and most patients experience pain postoperatively requiring nursing attention to pain management. Scripting, recommended for consistent, targeted communication to improve patient satisfaction, has limited evidence to support its use. AIMS: To explore the effect of scripted messages on self-reported pain control and patient satisfaction with care in outpatient surgical patients. METHODS: A retrospective medical record review pre- and postintervention evaluated a pain management scripted message delivered at two time points (preoperatively and postoperatively)...
May 15, 2018: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/29762418/emergency-intubation-early-identification-and-strategic-management-can-save-lives
#4
Joshua A Bloomstone, Randal O Dull, William F Eckhardt, William T McGee
No abstract text is available yet for this article.
June 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29752503/correction-to-the-relationship-of-pelvic-incidence-to-post-operative-total-hip-arthroplasty-dislocation-in-patients-with-lumbar-fusion
#5
Philip J York, Alan W McGee, Chase S Dean, Justin E Hellwinkel, Christopher J Kleck, Michael R Dayton, Craig A Hogan
The original publication of this paper contain an error. The author name "Alan S. McGee Jr" is incorrect for it should have been "Alan W. McGee Jr".
May 11, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29742665/variation-in-the-nulliparous-term-singleton-vertex-cesarean-delivery-rate
#6
Daniel N Pasko, Paula McGee, William A Grobman, Jennifer L Bailit, Uma M Reddy, Ronald J Wapner, Michael W Varner, John M Thorp, Kenneth J Leveno, Steve N Caritis, Mona Prasad, George Saade, Yoram Sorokin, Dwight J Rouse, Sean C Blackwell, Jorge E Tolosa
OBJECTIVE: To estimate the contributions of patient and health care provider-hospital characteristics to the variation in the frequency of nulliparous, term, singleton, vertex cesarean delivery in a multi-institutional U.S. cohort. METHODS: We performed a secondary analysis of the multicenter Assessment of Perinatal Excellence cohort of 115,502 mother and neonatal pairs who were delivered at 25 hospitals between March 2008 and February 2011. Women met inclusion criteria if they were nulliparous and delivered a singleton in vertex presentation at term...
May 7, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29727049/multifactorial-analysis-of-opsoclonus-myoclonus-syndrome-etiology-tumor-vs-no-tumor-in-a-cohort-of-356-us-children
#7
Michael R Pranzatelli, Elizabeth D Tate, Nathan R McGee
BACKGROUND: Pediatric opsoclonus-myoclonus syndrome (OMS) presents a paradox of etiopathogenesis: A neuroblastic tumor (NB) is found in only one half of the cases, the others are ascribed to infections or designated as idiopathic. METHOD: From an IRB-approved observational study of 356 US children with OMS, secondary analysis of "etiology" and related factors was performed on a well-characterized cohort. The "Tumor" (n = 173) and "No Tumor" groups (n = 183), as defined radiologically, were compared according to multiple factors considered potentially differentiating...
May 4, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29726727/epigenetic-therapy-and-dermatologic-disease-moving-beyond-ctcl
#8
Joshua S Mervis, Jean S McGee
The epigenetic regulation of gene expression is accomplished primarily through DNA methylation, histone modification, and gene silencing via the action of microRNAs. While previously very difficult to study, the field of epigenetics has been greatly facilitated by recent technological innovations. Alterations in the epigenome and epigenetic machinery are now known to be present in a variety of diseases, most notably cancers. Moreover, evidence has emerged that epigenetic dysregulation plays a causative role in disease pathogenesis...
May 4, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29723026/crisis-counselor-perceptions-of-job-training-stress-and-satisfaction-during-disaster-recovery
#9
Nikki D Bellamy, Min Qi Wang, Lori A McGee, Julie S Liu, Maryann E Robinson
OBJECTIVE: The United States Crisis Counseling Assistance and Training Program (CCP; authorized by the Robert T. Stafford Disaster Relief and Emergency Assistance Act, 1974/2013) aims to provide disaster-recovery support to communities following natural or human-caused disasters through outreach. Job satisfaction among the crisis counselors the CCP employs may affect the delivery of outreach services to survivors and their communities. The present study was conducted to gain insight into CCP crisis counselors' experiences with job training and work-related stress as predictors of job satisfaction...
May 3, 2018: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29720431/global-distribution-of-invasive-serotype-35d-streptococcus-pneumoniae-post-pcv13-introduction
#10
Stephanie W Lo, Rebecca A Gladstone, Andries J van Tonder, Paulina A Hawkins, Brenda Kwambana-Adams, Jennifer E Cornick, Shabir A Madhi, Susan A Nzenze, Mignon du Plessis, Rama Kandasamy, Philip E Carter, Özgen Köseoglu Eser, Pak Leung Ho, Naima Elmdaghri, Sadia Shakoor, Stuart C Clarke, Martin Antonio, Dean B Everett, Anne von Gottberg, Keith P Klugman, Lesley McGee, Robert F Breiman, Stephen D Bentley
A newly recognized pneumococcal serotype 35D, which differs from the 35B polysaccharide in structure and serology by not binding to factor serum 35a, was recently reported. The genetic basis for this distinctive serology is due to the presence of an inactivating mutation in wciG , which encodes an O-acetyltransferase responsible for O-acetylation of a galactofuranose. Here, we assessed the genomic data of a worldwide pneumococcal collection to identify serotype 35D isolates and understand their geographical distribution, genetic background and invasiveness potential...
May 2, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29712621/incidence-of-lower-respiratory-tract-infections-and-atopic-conditions-in-boys-and-young-male-adults-royal-college-of-general-practitioners-research-and-surveillance-centre-annual-report-2015-2016
#11
Simon de Lusignan, Ana Correa, Richard Pebody, Ivelina Yonova, Gillian Smith, Rachel Byford, Sameera Rankiri Pathirannehelage, Christopher McGee, Alex J Elliot, Mariya Hriskova, Filipa Im Ferreira, Imran Rafi, Simon Jones
BACKGROUND: The Royal College of General Practitioners Research and Surveillance Centre comprises more than 150 general practices, with a combined population of more than 1.5 million, contributing to UK and European public health surveillance and research. OBJECTIVE: The aim of this paper was to report gender differences in the presentation of infectious and respiratory conditions in children and young adults. METHODS: Disease incidence data were used to test the hypothesis that boys up to puberty present more with lower respiratory tract infection (LRTI) and asthma...
April 30, 2018: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/29709517/maximally-informative-next-experiments-for-nonlinear-models
#12
Reginald L McGee, Gregery T Buzzard
Mathematical modeling is a powerful tool in systems biology; we focus here on improving the reliability of model predictions by reducing the uncertainty in model dynamics through experimental design. Model-based experimental design is a process by which experiments can be systematically chosen to reduce dynamic uncertainty in a given model. We discuss the Maximally Informative Next Experiment (MINE) method for group-wise selection of points in an experimental design and present a convergence result for MINE with nonlinear models...
April 27, 2018: Mathematical Biosciences
https://www.readbyqxmd.com/read/29708429/us-food-and-drug-administration-approval-of-whole-slide-imaging-for-primary-diagnosis-a-key-milestone-is-reached-and-new-questions-are-raised
#13
Andrew J Evans, Thomas W Bauer, Marilyn M Bui, Toby C Cornish, Helena Duncan, Eric F Glassy, Jason Hipp, Robert S McGee, Doug Murphy, Charles Myers, Dennis G O'Neill, Anil V Parwani, B Alan Rampy, Mohamed E Salama, Liron Pantanowitz
April 12, 2017, marked a significant day in the evolution of digital pathology in the United States, when the US Food and Drug Administration announced its approval of the Philips IntelliSite Pathology Solution for primary diagnosis in surgical pathology. Although this event is expected to facilitate more widespread adoption of whole slide imaging for clinical applications in the United States, it also raises a number of questions as to the means by which pathologists might choose to incorporate this technology into their clinical practice...
April 30, 2018: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29706586/childhood-adversities-and-thriving-skills-sample-case-of-older-swiss-former-indentured-child-laborers
#14
Jan Höltge, Shauna L McGee, Andreas Maercker, Myriam V Thoma
OBJECTIVE: The study of life-long consequences of severe childhood adversities or trauma has recently received much attention. However, little is known about the subjective coping success and development of positively evaluated resources that may originate within these adverse experiences and may be conceptualized as thriving. This study set out to examine the relationship between thriving in response to early adversity and successful aging with a sample of former indentured child laborers in Switzerland (Verdingkinder)...
March 28, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29705905/concentration-dependent-responses-of-soil-bacterial-fungal-and-nitrifying-communities-to-silver-nano-and-micron-particles
#15
Conor Francis McGee, Sean Storey, Nicholas Clipson, Evelyn Doyle
The growing use of silver nanoparticles (AgNPs) is likely to result in increased environmental contamination. Although AgNPs have been reported to affect microbial communities in a range of ecosystems, there is still a lack of information concerning the effect of low concentrations of AgNPs on soil microbial community structures and functional groups involved in biogeochemical cycling. In this study, the concentration-dependent effects of AgNPs and silver micron particles (AgMPs) on bacterial and fungal community structures in an agricultural pastureland soil were examined in a microcosm-based experiment using enzyme analysis, molecular fingerprinting, qPCR and amplicon sequencing...
April 29, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29704024/the-relationship-of-pelvic-incidence-to-post-operative-total-hip-arthroplasty-dislocation-in-patients-with-lumbar-fusion
#16
Philip J York, Alan S McGee, Chase S Dean, Justin E Hellwinkel, Christopher J Kleck, Michael R Dayton, Craig A Hogan
PURPOSE: To determine if lumbar fusion increases the risk of dislocation following total hip arthroplasty (THA) via a posterior approach and to investigate anatomic variables associated with this increased risk. METHODS: Five-year retrospective review of THAs performed through a posterior approach identifying cases of post-operative dislocation. Patients were grouped into those with or without previous lumbar spine fusion. Lumbar fusion patients were then further analyzed in terms of cup position, pelvic incidence, sacral slope, and pelvic tilt to determine if there were specific variables associated with the increased risk of dislocation...
April 28, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29697574/strategies-for-fighting-medicare-fraud
#17
Jamie McGee, Leslie Sandridge, Cierra Treadway, Kimberly Vance, Alberto Coustasse
In 2014, the United States spent approximately $3 trillion on health care. Medicare accounted for $554 billion of these costs, and approximately $60 billion were squandered because of incorrect billing methods, abuse, and fraud. Types of fraud included kickbacks, upcoding, and organized fraudulent crimes. To reduce the financial burden associated with these activities, the United States has created various fraud prevention programs. The purpose of this study was to identify methods of Medicare fraud, examine the various programs implemented by the US government to combat fraud and abuse, and determine the effectiveness of these programs...
April 2018: Health Care Manager
https://www.readbyqxmd.com/read/29691147/maternal-high-fat-diet-induces-early-cardiac-hypertrophy-and-alters-cardiac-metabolism-in-sprague-dawley-rat-offspring
#18
K A De Jong, S Barrand, R J Wood-Bradley, D L de Almeida, J K Czeczor, G D Lopaschuk, J A Armitage, S L McGee
BACKGROUND AND AIM: Maternal high fat diets (mHFD) have been associated with an increased offspring cardiovascular risk. Recently we found that the class IIa HDAC-MEF2 pathway regulates gene programs controlling fatty acid oxidation in striated muscle. This same pathway controls hypertrophic responses in the heart. We hypothesized that mHFD is associated with activation of signal controlling class II a HDAC activity and activation of genes involved in fatty acid oxidation and cardiac hypertrophy in offspring...
March 13, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29685719/groin-haemostasis-with-a-purse-string-suture-for-patients-following-catheter-ablation-procedures-gitar-study
#19
Nicholas Jackson, Michael McGee, Waheed Ahmed, Allan Davies, Jim Leitch, Mark Mills, Matthew Cambourn, Saad Ezad, Andrew Boyle, John Attia, Kumaraswamy Nanthakumar, Malcolm Barlow
BACKGROUND: The most frequent complications from percutaneous electrophysiology procedures relate to vascular access. We sought to perform the first randomised controlled trial for femoral venous haemostasis utilising a simple and novel purse string suture (PSS) technique. METHODS: We randomised 200 consecutive patients who were referred for electrophysiology procedures at two different hospitals to either 10minutes of manual pressure or a PSS over the femoral vein and determined the incidence of vascular access site complications...
March 20, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29685330/relation-of-intrathecal-oligoclonal-band-production-to-inflammatory-mediator-and-immunotherapy-response-in-208-children-with-oms
#20
Michael R Pranzatelli, Nathan R McGee, Elizabeth D Tate
In 208 children with opsoclonus-myoclonus syndrome (OMS), CSF IgG oligoclonal bands (OCB) and 22 immunomarkers in CSF and 21 in serum/blood were measured. In 36 untreated OMS, 58% were OCB(+), whereas 55% of treated OMS were OCB(-). OCB positivity or negativity did not alter concentrations or frequencies of immunomarkers. The phenotypes of OCB(+) and OCB(-) patients were not distinctive. CSF B cells were expanded in untreated OMS regardless of OCB positivity. These data reveal a much higher frequency of OCB positivity in untreated OMS than previously realized and a disconnect between intrathecal OCB and inflammatory mediator production...
April 12, 2018: Journal of Neuroimmunology
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