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https://www.readbyqxmd.com/read/29778070/high-intensity-binge-drinking-is-associated-with-alterations-in-spontaneous-neural-oscillations-in-young-adults
#1
Rifqi O Affan, Siyuan Huang, Stephen M Cruz, Lee A Holcomb, Edward Nguyen, Ksenija Marinkovic
Heavy episodic alcohol consumption (also termed binge drinking) contributes to a wide range of health and cognitive deficits, but the associated brain-based indices are poorly understood. The current study used electroencephalography (EEG) to examine spontaneous neural oscillations in young adults as a function of quantity, frequency, and the pattern of their alcohol consumption. Sixty-one young adults (23.4 ± 3.4 years of age) were assigned to binge drinking (BD) and light drinking (LD) groups that were equated on gender, race/ethnic identity, age, educational background, and family history of alcoholism...
January 8, 2018: Alcohol
https://www.readbyqxmd.com/read/29752630/potentially-reversible-social-deficits-among-transgender-youth
#2
Jack L Turban
Recently, there has been increased attention to a putative relationship between Autism Spectrum Disorder (ASD) and gender dysphoria, the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) diagnosis for those whose gender assigned at birth does not match their gender identity. Studies have shown an over-representation of ASD symptoms among transgender youth. These studies, however, have used scales that are non-specific for ASD. These ASD symptoms may represent social deficits that are secondary to social stress and deprivation, as transgender youth suffer high rates of peer and family rejection...
May 12, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29741976/self-reported-autism-spectrum-disorder-symptoms-among-adults-referred-to-a-gender-identity-clinic
#3
Lieke E W Vermaat, Anna I R van der Miesen, Annelou L C de Vries, Thomas D Steensma, Arne Popma, Peggy T Cohen-Kettenis, Baudewijntje P C Kreukels
PURPOSE: The purpose of this study was to (1) investigate autism spectrum disorder (ASD) symptoms in a sample of adults referred for gender dysphoria (GD) compared to typically developing (TD) populations, (2) see whether males assigned at birth with GD (MaBGD s) and females assigned at birth with GD (FaBGD s) differ in ASD symptom levels, (3) study the role of sexual orientation, and (4) investigate ASD symptoms' correlation with GD symptoms. METHODS: The Autism-Spectrum Quotient (AQ) was used to measure ASD symptoms, and the Utrecht Gender Dysphoria Scale (UGDS) was used to measure the intensity of GD...
May 9, 2018: LGBT Health
https://www.readbyqxmd.com/read/29736897/the-normalization-of-intersex-bodies-and-othering-of-intersex-identities-in-australia
#4
EDITORIAL
Morgan Carpenter
Once described as hermaphrodites and later as intersex people, individuals born with intersex variations are routinely subject to so-called "normalizing" medical interventions, often in childhood. Opposition to such practices has been met by attempts to discredit critics and reasserted clinical authority over the bodies of women and men with "disorders of sex development." However, claims of clinical consensus have been selectively constructed and applied and lack evidence. Limited transparency and lack of access to justice have helped to perpetuate forced interventions...
May 7, 2018: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/29730870/effects-of-gender-reassignment-on-quality-of-life-and-mental-health-in-people-with-gender-dysphoria
#5
Berna Özata Yıldızhan, Şahika Yüksel, Mirella Avayu, Handan Noyan, Eren Yıldızhan
OBJECTIVE: Our purpose was to compare the life style, family and social relationships (social adaptation) and the quality of life in people with gender dysphoria with and without history of sex reassignment surgery. METHOD: Twenty  individuals (SR group) who were earlier followed   in Istanbul University Psychiatry Department Psychoneurosis and Psychotherapy Unit with gender dysphoria diagnosis in  order  to  have confirmative reports for the sex reassignment (SR) surgery were interviewed at least one year after the surgery...
2018: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
https://www.readbyqxmd.com/read/29715194/trends-in-the-use-of-puberty-blockers-among-transgender-children-in-the-united-states
#6
Carla Marisa Lopez, Daniel Solomon, Susan D Boulware, Emily R Christison-Lagay
BACKGROUND: The objective of the study was to identify national trends in the utilization of histrelin acetate implants among transgender children in the United States. METHODS: We analyzed demographic, diagnostic and treatment data from 2004 to 2016 on the use of histrelin acetate reported to the Pediatric Health Information System (PHIS) to determine the temporal trends in its use for transgender-related billing diagnoses, e.g. "gender identity disorder"...
May 1, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29674763/descriptive-study-of-gender-dysphoria-in-japanese-individuals-with-male-to-female-gender-identity-disorder
#7
Yoshie Shinohara, Mikiya Nakatsuka
We focus on Japanese individuals with gender identity disorder (GID), especially male-to-female (MTF) GID, who have experienced difficulty in adapting to social life. We clarify what gender dysphoria is, and we examine methods of intervention. Semi-structured interviews were conducted with 11 individuals with MTF-GID from August 2015 to April 2017. We categorized the subjects'experiences regarding dysphoria into the 'Onset of gender dysphoria,' 'Experience of feeling gender dysphoria,' and 'Changes due to receiving medical care...
April 2018: Acta Medica Okayama
https://www.readbyqxmd.com/read/29665513/levels-of-depression-in-transgender-people-and-its-predictors-results-of-a-large-matched-control-study-with-transgender-people-accessing-clinical-services
#8
Gemma L Witcomb, Walter Pierre Bouman, Laurence Claes, Nicola Brewin, John R Crawford, Jon Arcelus
BACKGROUND: Depression is a serious disorder which significantly impacts wellbeing and quality of life. Studies exploring mental wellbeing in the transgender population are mostly limited by small, non-homogenous samples and lack of matched controls. This study aimed to address these limitations and explore depression rates in a large sample of transgender people, compared with matched controls from the general population, as well as factors predicting depression in those taking cross-sex hormone treatment (CHT) compared to those not...
February 17, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29661941/mental-health-of-transgender-and-gender-nonconforming-youth-compared-with-their-peers
#9
Tracy A Becerra-Culqui, Yuan Liu, Rebecca Nash, Lee Cromwell, W Dana Flanders, Darios Getahun, Shawn V Giammattei, Enid M Hunkeler, Timothy L Lash, Andrea Millman, Virginia P Quinn, Brandi Robinson, Douglas Roblin, David E Sandberg, Michael J Silverberg, Vin Tangpricha, Michael Goodman
BACKGROUND: Understanding the magnitude of mental health problems, particularly life-threatening ones, experienced by transgender and/or gender nonconforming (TGNC) youth can lead to improved management of these conditions. METHODS: Electronic medical records were used to identify a cohort of 588 transfeminine and 745 transmasculine children (3-9 years old) and adolescents (10-17 years old) enrolled in integrated health care systems in California and Georgia. Ten male and 10 female referent cisgender enrollees were matched to each TGNC individual on year of birth, race and/or ethnicity, study site, and membership year of the index date (first evidence of gender nonconforming status)...
April 16, 2018: Pediatrics
https://www.readbyqxmd.com/read/29627104/a-systematic-review-of-social-stress-and-mental-health-among-transgender-and-gender-non-conforming-people-in-the-united-states
#10
REVIEW
Sarah E Valentine, Jillian C Shipherd
Transgender and gender non-conforming (TGNC) populations, including those who do not identify with gender binary constructs (man or woman) are increasingly recognized in health care settings. Research on the health of TGNC people is growing, and disparities are often noted. In this review, we examine 77 studies published between January 1, 1997 and March 22, 2017 which reported mental health outcomes in TGNC populations to (a) characterize what is known about mental health outcomes and (b) describe what gaps persist in this literature...
March 28, 2018: Clinical Psychology Review
https://www.readbyqxmd.com/read/29609904/translation-adaptation-and-preliminary-validation-of-dacakis-and-davies-transsexual-voice-questionnaire-male-to-female-in-french
#11
Dominique Morsomme, Joana Revis, Elisabeth Thomas
Transgender MtF people (trans women) consult otorhinolaryngologists and vocologists with the aim of feminizing their voice and being consistently perceived as women. Treatment of these trans women always begins with a vocal assessment that is relatively unspecific as it was originally constructed for individuals with dysphonia. OBJECTIVES: This study examines the subjective portion of the assessment and specifically the self-assessment questionnaire. There is no French-language questionnaire designed to identify the issues facing people who want voice feminization and quantify the impact of their voice disorder on their daily lives...
March 30, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/29608124/young-urban-adolescents-activity-spaces-close-peers-and-the-risk-of-cannabis-use-a-social-spatial-longitudinal-analysis
#12
Michael J Mason, Jeremy Mennis
BACKGROUND: An understudied, yet important area of youth development research is the examination of how place affects critical psychosocial processes such as identity formation, problem solving, emotional regulation, and in particular with adolescents, belongingness, autonomy, social competency, and behavioral health. A growing spatially informed literature indicates that youth interact with meaningful places as environmental strategies, shaping developmental trajectories related to behavioral health...
April 2, 2018: Substance Use & Misuse
https://www.readbyqxmd.com/read/29607345/women-s-perceptions-and-feelings-about-loss-of-their-sexual-desire-a-qualitative-study-in-iran
#13
Pouran Akhavan Akbari, Giti Ozgoli, Masoumeh Simbar, Mohammad Ali Besharat
Background: Reduced sexual desire leaves serious impacts on women's life. The current study aims to investigate the perceptions and concerns of Iranian women of reproductive age with female sexual interest and arousal disorder (FSIAD). Methods: This qualitative research was conducted using content analysis approach. Data were collected through seventeen in-depth interviews from October 2015 to June 2016. Purposive sampling was carried out from among reproductive-aged women suffering from FSIAD who responded to female sexual function index (FSFI) with mean scores of ≤3...
April 2018: International Journal of Community Based Nursing and Midwifery
https://www.readbyqxmd.com/read/29589251/hepatocellular-adenoma-in-a-woman-who-was-undergoing-testosterone-treatment-for-gender-identity-disorder
#14
Keizo Kato, Hiroshi Abe, Noriko Hanawa, Junya Fukuzawa, Ryota Matsuo, Takeshi Yonezawa, Sadahiro Itoh, Yoshiyuki Sato, Makiko Ika, Shohei Shimizu, Shinji Endo, Hiroshi Hano, Asami Izu, Masahiko Sugitani, Akihito Tsubota
A 32-year-old Japanese woman was admitted to our hospital for the diagnosis and treatment of multiple liver tumors. She had been receiving 125 mg testosterone enanthate every 2 weeks following female-to-male gender identity disorder (GID) diagnosis at 20 years of age. Ultrasonography, computed tomography, and magnetic resonance imaging showed 11 hepatic nodular tumors with a maximum diameter of 28 mm. Liver tumors with hepatocellular adenoma (HCA) were diagnosed with needle biopsy. Segmentectomy of the left lateral lobe including two lesions, subsegmentectomy of S6 including two lesions, enucleation of each tumor in S5 and S7, and open surgical radiofrequency ablation for each tumor in S4 and S7 were performed...
March 27, 2018: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29535648/somatic-experiencing-%C3%A2-informed-therapeutic-group-for-the-care-and-treatment-of-biopsychosocial-effects-upon-a-gender-diverse-identity
#15
Paul C Briggs, Sage Hayes, Michael Changaris
Background: Somatic Experiencing® (SE™) is a resiliency-based treatment for autonomic nervous systems dysregulation syndromes, such as posttraumatic stress disorder, anxiety, depression, and physical syndromes like chronic pain, migraines, and fibromyalgia. "Transgender/gender non-conforming/gender variant" describes people whose gender identity/expression is different, at least part of the time, from the sex assigned at birth. Research indicates transgender individuals have a higher incidence of depression, anxiety, victimization, and discrimination...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29514430/barriers-to-transition-related-healthcare-among-korean-transgender-adults-focused-on-gender-identity-disorder-diagnosis-hormone-therapy-and-sex-reassignment-surgery
#16
Hyemin Lee, Jooyoung Park, Bokyoung Choi, Horim Yi, Seung-Sup Kim
Objectives: Previous literature has documented that transgender people may encounter barriers when they use transition-related healthcare services. This study aims to investigate the experiences of transition-related healthcare and the barriers to those services among transgender adults in South Korea. Methods: In 2017, we conducted a nationwide cross-sectional survey of 278 transgender adults in South Korea. We assessed the prevalence of transition-related healthcare such as Gender Identity Disorder (GID) diagnosis, hormone therapy, and sex reassignment surgery...
February 27, 2018: Epidemiology and Health
https://www.readbyqxmd.com/read/29507583/a-novel-homozygous-mutation-in-desert-hedgehog-dhh-in-a-46-xy-patient-with-dysgenetic-testes-presenting-with-primary-amenorrhoea-a-case-report
#17
Karen M Rothacker, Katie L Ayers, Dave Tang, Kiranjit Joshi, Jocelyn A van den Bergen, Gorjana Robevska, Naeem Samnakay, Lakshmi Nagarajan, Kate Francis, Andrew H Sinclair, Catherine S Choong
Background: Desert hedgehog ( DHH ) mutations have been described in only a limited number of individuals with 46, XY disorders of sex development (DSD) presenting as either partial or complete gonadal dysgenesis. Gonadal tumours and peripheral neuropathy have been associated with DHH mutations. Herein we report a novel, homozygous mutation of DHH identified through a targeted, massively parallel sequencing (MPS) DSD panel, in a patient presenting with partial gonadal dysgenesis. This novel mutation is two amino acids away from a previously described mutation in a patient who presented with complete gonadal dysgenesis...
2018: International Journal of Pediatric Endocrinology
https://www.readbyqxmd.com/read/29503778/transgender-associations-and-possible-etiology-a-literature-review
#18
REVIEW
Fatima Saleem, Syed W Rizvi
Transgender or gender dysphoria has been defined in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), as distress resulting from the incongruence between one's experienced gender and one's assigned gender, along with a persistent and strong desire to be of another gender, and accompanied by clinically significant distress. Adolescents referred for evaluation often want hormonal therapy and several among them also express a desire for gender reassignment surgery. Furthermore, evidence shows that adolescents and adults with gender dysphoria without a sex development disorder, before gender reassignments, are at increased risk for suicide...
December 24, 2017: Curēus
https://www.readbyqxmd.com/read/29496142/the-art-of-matching-brain-tissue-from-patients-and-controls-for-postmortem-research
#19
Ai-Min Bao, Dick F Swaab
The quality of postmortem research depends strongly on a thorough clinical investigation and documentation of the patient's disorder and therapies. In addition, a systematic and professional neuropathologic investigation of both cases and controls is absolutely crucial. In the experience of the Netherlands Brain Bank (NBB), about 20% of clinical neurologic diagnoses, despite being made in first-rate clinics, have to be revised or require an extra diagnosis after a complete and thorough review by the NBB. The neuropathology examination may reveal for instance that the "controls" already have preclinical neurodegenerative alterations...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29490365/temporal-trends-in-gender-affirming-surgery-among-transgender-patients-in-the-united-states
#20
Joseph K Canner, Omar Harfouch, Lisa M Kodadek, Danielle Pelaez, Devin Coon, Anaeze C Offodile, Adil H Haider, Brandyn D Lau
Importance: Little is known about the incidence of gender-affirming surgical procedures for transgender patients in the United States. Objectives: To investigate the incidence and trends over time of gender-affirming surgical procedures and to analyze characteristics and payer status of transgender patients seeking these operations. Design, Setting, and Participants: In this descriptive observational study from 2000 to 2014, data were analyzed from the National Inpatient Sample, a representative pool of inpatient visits across the United States...
February 28, 2018: JAMA Surgery
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