Hyun-Jeong Kim, So-Yeon Kim, Ho Jung Bae, Yu-Yeong Choi, Ju-Yeon An, Ye Eun Cho, So-Young Cho, Su-Jung Lee, Sanghyun Lee, MinSub Sin, Young Min Yun, Jong Ryul Lee, Se Jin Park
Atopic dermatitis (AD) is a chronic inflammatory skin disease influenced by a complex interplay of genetic and environmental factors. The activation of the JAK-STAT pathway increases the expression of inflammatory cytokines such as IL-4 and IL-13, further deteriorating AD. Therefore, for the treatment of AD, the JAK-STAT pathway is emerging as a significant target, alongside inflammatory cytokines. This study investigates the potential therapeutic effects of a novel herbal complex, LK5, composed of Scutellaria baicalensis , Liriope platyphylla , Sophora flavescens , Dictammus dasycarpus , and Phellodendron schneider , known for their anti-inflammatory and immune-modulating properties...
December 27, 2023: Pharmaceutics