keyword
MENU ▼
Read by QxMD icon Read
search

Dfu

keyword
https://www.readbyqxmd.com/read/28633819/effects-of-ultrasound-pretreatment-with-different-frequencies-and-working-modes-on-the-enzymolysis-and-the-structure-characterization-of-rice-protein
#1
Xue Yang, Yunliang Li, Suyun Li, Ayobami Olayemi Oladejo, Siyu Ruan, Yucheng Wang, Shanfen Huang, Haile Ma
The effects of ultrasound pretreatment with different frequencies and working modes, including mono-frequency ultrasound (MFU), dual-frequency ultrasound (DFU) and tri-frequency ultrasound (TFU), on the degree of hydrolysis (DH) of rice protein (RP) and angiotensin-I-converting enzyme (ACE) inhibitory activity of RP hydrolysate were investigated. Ultraviolet-visible (UV) spectroscopy, fourier transform infrared (FTIR) spectroscopy, surface hydrophobicity and scanning electron microscopy (SEM) of RP pretreated with ultrasound were measured...
September 2017: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/28627224/real-time-smart-textile-based-system-to-monitor-pressure-offloading-of-diabetic-foot-ulcers
#2
Andrea Raviglione, Roberto Reif, Maurizio Macagno, Davide Vigano, Justin Schram, David Armstrong
BACKGROUND: The lifetime risk of developing a diabetic foot ulcer (DFU) is at least 25%. A DFU carries a 50% risk for infection and at least 20% of those receive some form of amputation. The most significant parameter that prevents or delays ulcer healing is high plantar pressure. To improve the patient's healing process, the DFU's plantar pressure should remain cumulatively low. Therefore, a tool that continuously measures the DFU loading, and provides real-time feedback can improve the healing outcome...
February 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28602059/depth-and-combined-infection-is-important-predictor-of-lower-extremity-amputations-in-hospitalized-diabetic-foot-ulcer-patients
#3
Eun-Gyo Jeong, Sung Shim Cho, Sang-Hoon Lee, Kang-Min Lee, Seo-Kyung Woo, Yoongoo Kang, Jae-Seung Yun, Seon-Ah Cha, Yoon-Jung Kim, Yu-Bae Ahn, Seung-Hyun Ko, Jung-Min Lee
Background/Aims: As the prevalence of diabetes mellitus and its complications increase rapidly, diabetic foot ulcers (DFUs), which are a major diabetic complication, are expected to increase. For prevention and effective treatment, it is important to understand the clinical course of DFUs. The aim of this study was to investigate the natural course and predictors of amputation in patients with DFUs who required hospitalization. Methods: A total of 209 patients with type 2 diabetes, aged 30 to 85 years, who visited emergency department or needed hospitalization due to DFUs were consecutively enrolled from May 2012 to January 2016, by retrospective medical record review...
June 7, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28598042/peripheral-vascular-disease-in-patients-with-diabetic-foot-ulcers-an-emerging-trend-a-prospective-study-from-north-india
#4
Supriya Bajaj, Amit Mahajan, Sumit Grover, Vijay Mahajan, Pankaj Goyal, Vikram Kumar Gupta
BACKGROUND: Diabetic foot ulcer is one of the chronic complications of diabetes mellitus (DM) with 25% of patients with diabetes developing a foot ulcer during their lifetime leading to amputation. Diabetic foot is classified into 2 main types: neuropathic ulcers (NPU) and neuro-ischemic ulcer (NIU) where in addition to neuropathy peripheral vascular disease (PVD) is also present. AIMS: We aimed to a) assess the prevalence of Peripheral vascular disease (PVD) in patients of type 2 diabetes mellitus (T2DM) presenting with New Diabetic Foot ulcers (DFU)...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28597935/failure-rates-of-artificial-dermis-products-in-treatment-of-diabetic-foot-ulcer-a-systematic-review-and-network-meta-analysis
#5
Huidi Tchero, Christian Herlin, Farid Bekara, Pauline Kangambega, Fluieraru Sergiu, Luc Teot
Diabetic foot ulcer (DFU) is a frequent complication in diabetic patients, occurring in up to 25% of those affected. Among the treatments available to clinicians, the use of bioengineered skin substitutes is an attractive alternative. Artificial dermis functions as a matrix, covering the wound and supporting healing and reconstruction of the lost tissue. This study was aimed at reviewing the use of five regeneration matrices (namely, Integra, Nevelia, Matriderm, Pelnac, and Renoskin) as reported by clinical trials...
June 8, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28581122/the-application-of-wireless-near-infrared-spectroscopy-on-detecting-peripheral-circulation-in-patients-with-diabetes-foot-ulcer-when-doing-buerger-s-exercise
#6
Min-Ling Chen, Bor-Shyh Lin, Cheng-Wei Su, Yen-Bin Lin, Mei-Yen Chen, Jen-Hsiang Shen, Chang-Cheng Chang
BACKGROUND AND OBJECTIVES: The majority of patients with diabetes foot ulcer have peripheral arterial disease. The technique of near infrared spectroscopy (NIRS) used to monitor the dorsal foot blood circulation condition is by measuring the absorption differences between oxy-hemoglobin and deoxy-hemoglobin. STUDY DESIGNS/MATERIALS AND METHODS: Patients with diabetic foot ulcer (DFU) treated in our wound care center were divided into two sub-groups based on the Duplex ultrasound or angiography...
June 5, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28545120/incidence-and-risk-factors-for-developing-infection-in-patients-presenting-with-uninfected-diabetic-foot-ulcers
#7
Limin Jia, Christina N Parker, Tony J Parker, Ewan M Kinnear, Patrick H Derhy, Ann M Alvarado, Flavia Huygens, Peter A Lazzarini
OBJECTIVE: There is a paucity of research on patients presenting with uninfected diabetic foot ulcers (DFU) that go on to develop infection. We aimed to investigate the incidence and risk factors for developing infection in a large regional cohort of patients presenting with uninfected DFUs. METHODS: We performed a secondary analysis of data collected from a validated prospective state-wide clinical diabetic foot database in Queensland (Australia). Patients presenting for their first visit with an uninfected DFU to a Diabetic Foot Service in one of thirteen Queensland regions between January 2012 and December 2013 were included...
2017: PloS One
https://www.readbyqxmd.com/read/28540570/magnesium-supplementation-and-the-effects-on-wound-healing-and-metabolic-status-in-patients-with-diabetic-foot-ulcer-a-randomized-double-blind-placebo-controlled-trial
#8
Reza Razzaghi, Farangis Pidar, Mansooreh Momen-Heravi, Fereshteh Bahmani, Hossein Akbari, Zatollah Asemi
Hypomagnesemia is associated with the development of neuropathy and abnormal platelet activity, both of which are risk factors for diabetic foot ulcer (DFU). This study was carried out to evaluate the effects of magnesium administration on wound healing and metabolic status in subjects with DFU. This randomized, double-blind, placebo-controlled trial was performed among 70 subjects with grade 3 DFU. Subjects were randomly divided into two groups (35 subjects each group) to receive either 250 mg magnesium oxide supplements or placebo daily for 12 weeks...
May 24, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28532226/novel-biological-therapies-for-the-treatment-of-diabetic-foot-ulcers
#9
Jennifer Adeghate, Syed Nurulain, Kornélia Tekes, Erzsébet Fehér, Huba Kalász, Ernest Adeghate
The number of people with diabetes mellitus (DM) is estimated to exceed 640 million by the year 2040. Diabetic foot ulcer (DFU) is a debilitating illness that affects more than 2% of DM patients. DFU is caused by DM-induced neural and vascular lesions leading to a reduced sensation and microcirculation. The increase in the prevalence of DFU has prompted researchers to find new therapies for the management of DFU. Areas covered: This review presents the current status of novel biological therapies used in the treatment of DFU...
June 1, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28522400/impact-of-lysyl-oxidase-g473a-polymorphism-on-diabetic-foot-ulcers
#10
Sivakamasundari Pichu, Jayalalitha Sathiyamoorthy, Selvaraj Vimalraj, Vijay Viswanathan, Suvro Chatterjee
Lysyl oxidase (LOX) is an extra-cellular matrix-modifying enzyme that has been linked to cell proliferation, metastasis, angiogenesis and wound healing. This study was designed to examine the association of LOX gene polymorphism G473A, G>A, (rs1800449) located in exon 1 of the LOX gene in diabetic subjects with and without diabetic foot ulcers (DFU) and its impact of expression on DFU. Genotypic analysis of 906 samples showed a significant increase in the presence of 'A' allele in type 2 diabetes mellitus (T2DM) and DFU when compared to that of control subjects...
May 15, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28499789/association-between-the-polymorphism-of-glu298asp-in-exon-7-of-the-enos-gene-with-foot-ulcer-and-oxidative-stress-in-patients-with-type-2-diabetes
#11
Seyedeh Maryam Sadati, Mania Radfar, Armita Kakavand Hamidi, Mohammad Abdollahi, Mostafa Qorbani, Ensieh Nasli Esfahani, Mahsa M Amoli
OBJECTIVES: Diabetic foot ulcer (DFU) is a common and major manifestation in patients with diabetes. Oxidative stress (OS) plays an important role in diabetic complications, such as DFU. Nitric oxide deficiency contributes to the impairment of diabetic wound healing. The aim of this study was to examine the association between the eNOS Glu298Asp polymorphism and DFU and oxidative stress in patients with type 2 diabetes mellitus in an Iranian population. METHODS: In this case-control study, 123 patients with type 2 diabetes and DFU and 134 patients without DFU were recruited...
May 10, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28498862/severity-and-duration-of-diabetic-foot-ulcer-dfu-before-seeking-care-as-predictors-of-healing-time-a-retrospective-cohort-study
#12
Hilde Smith-Strøm, Marjolein M Iversen, Jannicke Igland, Truls Østbye, Marit Graue, Svein Skeie, Bei Wu, Berit Rokne
OBJECTIVES: To investigate whether A) duration of ulcer before start of treatment in specialist health care, and B) severity of ulcer according to University of Texas classification system (UT) at start of treatment (baseline), are independent predictors of healing time. METHODS: This retrospective cohort study, based on electronic medical record data, included 105 patients from two outpatient clinics in Western Norway with a new diabetic foot ulcer during 2009-2011...
2017: PloS One
https://www.readbyqxmd.com/read/28482622/nonlinear-dynamics-of-skin-blood-flow-response-to-mechanical-and-thermal-stresses-in-the-plantar-foot-of-diabetics-with-peripheral-neuropathy
#13
Fuyuan Liao, Yih-Kuen Jan
BACKGROUND: Diabetic foot ulcers (DFU) are a major complication in diabetics. Impaired microvascular reactivity is a major contributor to the development of DFU and has been traditionally quantified by time-domain or frequency-domain measures of skin blood flow (SBF). These measures, however, are unable to characterize the changes of nonlinear dynamics of SBF associated with diabetes and peripheral neuropathy. OBJECTIVE: The objective of this study was to investigate altered nonlinear dynamics of skin blood flow in the plantar foot of diabetics with peripheral neuropathy...
May 5, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28479156/multi-center-feasibility-study-of-microwave-radiometry-thermometry-for-non-invasive-differential-diagnosis-of-arterial-disease-in-diabetic-patients-with-suspected-critical-limb-ischemia
#14
Stavros Spiliopoulos, Vasiliki Theodosiadou, Nikolaos Barampoutis, Konstantinos Katsanos, Periklis Davlouros, Lazaros Reppas, Panagiotis Kitrou, Konstantinos Palialexis, Chrysostomos Konstantos, Elias Siores, Dimitrios Alexopoulos, Dimitris Karnabatidis, Elias Brountzos
AIMS: Diagnosis of vascular involvement in diabetic foot ulceration (DFU) remains challenging. We conducted a proof of concept study to investigate the feasibility of microwave radiometry (MWR) thermometry for non-invasive differential diagnosis of critical limb ischemia (CLI) in subjects with DFU. METHODS: This prospective, multi-center, study included 80 participants, divided into four groups (group N: normal control subjects; group DN: participants with diabetes and verified neuropathic ulcers without vascular involvement; group DC: participants with diabetes and CLI and group NDC: participants with CLI without diabetes)...
April 28, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28465454/feasibility-and-efficacy-of-a-smart-mat-technology-to-predict-development-of-diabetic-plantar-ulcers
#15
Robert G Frykberg, Ian L Gordon, Alexander M Reyzelman, Shawn M Cazzell, Ryan H Fitzgerald, Gary M Rothenberg, Jonathan D Bloom, Brian J Petersen, David R Linders, Aksone Nouvong, Bijan Najafi
OBJECTIVE: We conducted a multicenter evaluation of a novel remote foot-temperature monitoring system to characterize its accuracy for predicting impending diabetic foot ulcers (DFU) in a cohort of patients with diabetes with previously healed DFU. RESEARCH DESIGN AND METHODS: We enrolled 132 participants with diabetes and prior DFU in this 34-week cohort study to evaluate a remote foot-temperature monitoring system (ClinicalTrials.gov Identifier NCT02647346). The study device was a wireless daily-use thermometric foot mat to assess plantar temperature asymmetries...
May 2, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28457703/diabetic-complications-do-not-hamper-improvement-of-health-related-quality-of-life-over-the-course-of-treatment-of-diabetic-foot-ulcers-the-eurodiale-study
#16
Volkert Siersma, Hanne Thorsen, Per E Holstein, Marleen Kars, Jan Apelqvist, Edward B Jude, Alberto Piaggesi, Karel Bakker, Michael Edmonds, Alexandra Jirkovská, Didac Mauricio, Heinrich Reike, Maximilian Spraul, Luigi Uccioli, Vilma Urbancic, Kristien van Acker, Jeff van Baal, Nicolaas C Schaper
AIMS: Diabetic complications, and in particular diabetic foot ulcers (DFUs), are associated with low health-related quality of life (HRQoL). We evaluated whether the presence of diabetic complications also influenced the improvement of HRQoL during DFU treatment. METHODS: 1088 patients presenting for DFU treatment at the centers participating in the Eurodiale study were followed prospectively up to one year. HRQoL was measured both at presentation and after healing or at end of follow up, using EQ-5D: a standardized instrument consisting of five domains and a summary index...
April 13, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28448266/a-prospective-randomized-blinded-controlled-trial-comparing-transdermal-continuous-oxygen-delivery-to-moist-wound-therapy-for-the-treatment-of-diabetic-foot-ulcers
#17
Vickie R Driver, Alexander Reyzelman, Jill Kawalec, Michael French
Worldwide, diabetic foot ulcers (DFUs) continue to exact a major burden on patients and health care providers. Although hyperbaric oxygen therapy is well-known as an adjunct option, less is known about the efficacy of transdermal continuous oxygen therapy (TCOT). A prospective, randomized, blinded, multicenter, parallel study was conducted from October 2009 to November 2012 to evaluate healing time and the proportion of DFUs healed after 12 weeks of moist wound therapy (MWT) with or without TCOT. Study participants (persons with type 1 or type 2 diabetes and a nonhealing [>1-month but <1-year duration], 1 cm² to 10 cm² in area, infection-free DFU) were randomized to TCOT or a sham device (control) in addition to receiving MWT...
April 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/28448264/use-of-ovine-based-collagen-extracellular-matrix-and-gentian-violet-methylene-blue-antibacterial-foam-dressings-to-help-improve-clinical-outcomes-in-lower-extremity-wounds-a-retrospective-cohort-study
#18
Eric L Lullove
Dressings that provide broad spectrum metalloprotease reduction along with inherent aspects of an extracellular matrix may contribute to improved wound healing outcomes and shorter treatment times. OBJECTIVE: The author performed a retrospective case series analysis to determine the clinical outcomes of regular debridement with the use of ovine-based collagen extracellular matrix dressings and gentian violet/methylene blue polyurethane antibacterial foam dressings in treating 53 patients with 53 chronic lower extremity wounds (diabetic foot ulcers [DFUs], venous leg ulcers, and heel pressure ulcers)...
April 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28440774/diagnostic-and-therapeutic-update-on-diabetic-foot-osteomyelitis
#19
José Luis Lázaro-Martínez, Aroa Tardáguila-García, José Luis García-Klepzig
Diabetic foot osteomyelitis (DFO) is the most common infection associated to diabetic foot ulcers (DFU). This review is designed to provide an update on the diagnosis and treatment of DFO based on an analysis of MEDLINE through PubMed using as search criterion "Diabetic Foot Osteomyelitis". Authors have included in this review the most relevant manuscripts regarding diagnosis and treatment of DFO. After review and critical analysis of publications, it may be concluded that diagnosis of DFO is not simple because of its heterogeneous presentation...
February 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/28424173/association-between-estimated-glomerular-filtration-rate-and-outcomes-in-patients-with-diabetic-foot-ulcers-a-3-year-follow-up-study
#20
Yang He, Hongjie Qian, Lei Xu, Shanshan Zhang, Xueming Gu, Junyi Gu, Jianyuan Shi, Yaping Shen, Jianmin Liu, Zhengyi Tang
OBJECTIVE: End-stage renal disease and dialysis have been proven to be associated with poor prognoses in diabetic foot ulcers (DFUs). However, it has rarely been reported whether and to what extent milder renal insufficiency affects the prognosis. The purpose of this study was to investigate the categorized impact of estimated glomerular filtration (eGFR) on the outcomes of patients with DFU. DESIGN AND METHODS: Three hundred and sixty-six DFU patients hospitalized in a Chinese tertiary hospital were recruited and classified into 4 groups according to the eGFRs as follows: normal (≥90), mildly reduced (60-89), moderately reduced (30-59), and severely reduced (<30)...
July 2017: European Journal of Endocrinology
keyword
keyword
25078
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"