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Longterm Outcome

Julie E Davidson, Qinggong Fu, Beulah Ji, Sapna Rao, David Roth, Laurence S Magder, Michelle Petri
OBJECTIVE: This observational study was a retrospective analysis of prospectively collected Hopkins Lupus Cohort data to compare longterm renal survival in patients with lupus nephritis (LN) who achieved complete (CR), partial (PR), or no remission following standard-of-care LN induction therapy. METHODS: Eligible patients with biopsy-proven LN (revised American College of Rheumatology or Systemic Lupus Collaborating Clinics criteria) were identified and categorized into ordinal (CR, PR, or no remission) or binary (response or no response) renal remission categories at 24 months post-diagnosis [modified Aspreva Lupus Management Study (mALMS) and modified Belimumab International Lupus Nephritis Study (mBLISS-LN) criteria]...
March 1, 2018: Journal of Rheumatology
V K Zafiraki, E D Kosmachyeva, L V Shulzhenko, D M Ramazanov, A A Omarov, I V Pershukov
OBJECTIVE: to assess the effect of lung hyperinflation (LHI) in patients with chronic obstructive pulmonary disease (COPD) on longterm outcomes of percutaneous coronary intervention (PCI). MATERIALS AND METHODS: Patients with COPD who suffered stable ischemic heart disease and underwent PCI (n=135) were included in a prospective cohort study. LHI was found in 60 patients, while 75 patients had no LHI. Evaluation included comparing the frequency of major adverse cardiac events (MACE) (cardiac death, myocardial infarcпункtion [MI], stroke, repeat revascularization) and Kaplan-Mayer curves between groups of patients with and without LHI...
January 2018: Kardiologiia
Julius Moratin, Andreas Fuchs, Carolin Zeidler, Urs D A Müller-Richter, Roman C Brands, Stefan Hartmann, Alexander C Kübler, Christian Linz
INTRODUCTION: Squamous cell carcinoma of the maxilla only constitutes a small fraction of Head and Neck Cancers. There is thereby a lack of information about frequent tumor staging and localization and their effect on patients' outcome. The main factors that influence longterm survival in HNSCC are the extent of the primary disease and recurrence rate, including local neck metastases. PATIENTS AND METHODS: In this study, clinical outcome and rates of disease recurrence in 68 surgically treated patients with maxillary SCC were evaluated in terms of primary tumor staging and localization...
February 2, 2018: Journal of Cranio-maxillo-facial Surgery
Cai Yue, Guanhong Li, Yubing Wen, Xuemei Li, Ruitong Gao
OBJECTIVE: To investigate the renal protective effects of early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN). METHODS: Medical data of 57 SLE patients with biopsy-proven aPLN were analyzed. Early RAAS blockade was defined as administration of RASI within 3 months after kidney biopsy and continued for ≥ 12 months...
February 15, 2018: Journal of Rheumatology
Fanghao Cai, Fei Han, Hongya Wang, Haidongqin Han, Jingyun Le, Lan Lan, Ying Xu, Jianghua Chen
OBJECTIVE: To determine the association between crescents and renal outcomes, and the implications on therapeutic choices. METHODS: There were 231 patients with biopsy-proven proliferative lupus nephritis (PLN) who were divided into 4 groups: 59 patients were in the noncrescent group (NC); 59 patients exclusively with segmental crescents were in the segmental crescent group (SC); patients with circumferential crescents were categorized into 2 groups according to the crescentic ratio (C1 had 64 patients with ≤ 25%, and C2 had 49 patients with > 25%)...
February 15, 2018: Journal of Rheumatology
Christoph J Wagner, Charalabos Markos Dintsios, Florian G Metzger, Helmut L'Hoest, Ursula Marschall, Bjoern Stollenwerk, Stephanie Stock
OBJECTIVES: To measure persistence and nonrecurrence of depression treatment and investigate potential risk factors. METHODS: We retrospectively observed a closed cohort of insurees with new-onset depression treatment in 2007 and without most psychiatric comorbidity for 16 quarters (plus one to ascertain discontinuation). We linked inpatient/outpatient/drug-data per person and quarter. Person-quarters containing specified depression services were classified as depression-treatment-person-quarters (DTPQ)...
February 15, 2018: International Journal of Methods in Psychiatric Research
Akinori Hara, Takashi Wada, Ken-Ei Sada, Koichi Amano, Hiroaki Dobashi, Masayoshi Harigai, Yoshinari Takasaki, Hidehiro Yamada, Hitoshi Hasegawa, Taichi Hayashi, Shouichi Fujimoto, Eri Muso, Tamihiro Kawakami, Sakae Homma, Masaharu Yoshida, Junichi Hirahashi, Noriyoshi Ogawa, Satoshi Ito, Hirofumi Makino, Yoshihiro Arimura
OBJECTIVE: The aim was to elucidate the prognosis and risk factors associated with relapse during longterm remission maintenance therapy for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). METHODS: Patients with newly diagnosed AAV (n = 156) were registered in the Remission Induction Therapy in Japanese patients with ANCA-associated Vasculitides (RemIT-JAV) study, and among them, 83 patients who achieved remission were enrolled and followed up for 24 additional months in our nationwide, prospective cohort study (Co-RemIT-JAV; registration number UMIN 000006373)...
February 1, 2018: Journal of Rheumatology
D E Freeman
Colic surgery is one of few treatments in which a veterinarian can use a skill to save an animal's life from a deadly disease within a short timeframe. Unfortunately, such success is not achieved without considerable risk for surgical failure, which is responsible for most complications in the immediate postoperative period. The last 50 years have witnessed considerable improvements in colic surgery, although a ranking of the most important ones might not meet with universal agreement. Teamwork plays a critical role in the final outcome, starting and finishing with the referring veterinarian and owner...
February 6, 2018: Equine Veterinary Journal
Kyoko Hirasawa
Over the past few decades, advances in neonatal medicine have increased survival rates among very-low-birth-weight (VLBW) babies. Despite improvements in short-term outcomes, there is increasing concern about the probability of mild cognitive dysfunction in this population. Our analysis of VLBW babies born in our hospital revealed that the incidence of mild developmental disorders including autism spectrum disorder (ASD) and attention deficit hyperactive disorder (ADHD) at the age of 3 years is 7.2%, which is markedly higher than the 2...
2018: Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene
Kyung Il Jo, Na-Rae Yang, Pyoung Jeon, Keon Ha Kim, Seung-Chyul Hong, Jong Soo Kim
Objective: The objectives of this study were to evaluate the immediate and long-term efficacy and safety of coil embolization for large or giant aneurysms. Methods: One hundred and fifty large or giant aneurysm cases treated with endovascular coil embolization between January 2005 and February 2014 at a single institute were included in this study. Medical records and imaging findings were reviewed. Statistical analysis was performed to evaluate prognostic factors associated with major recurrence (major recanalization or rupture) and delayed thromboembolism after selective coil embolization...
January 2018: Journal of Korean Neurosurgical Society
J Cen, X L Kang, J Yu, L Y Dong, Y Wei, K X Zhao
Objective: To investigate clinical features and the long-term surgery results of Möbius syndrome patients. Methods: This investigation presents a retrospective study of Möbius syndrome in 7 children we found since 2009. All 7 patients had MRI scan, ocular alignment in primary position, the limitation of versions and ductions and forced duction under general anesthesia. Early surgery is done to the 7 esotropia children. The pre-operative and post-operative outcomes, including the ocular alignment, deviation measurements and ocular rotations, were evaluated and compared...
December 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Aaida Samad, Matthew L Stoll, Idit Lavi, Joyce J Hsu, Vibeke Strand, Thomas N Robinson, Elizabeth D Mellins, Devy Zisman
OBJECTIVE: Adult patients with psoriatic arthritis are at increased risk for obesity and metabolic syndrome, but data regarding adiposity in children with juvenile psoriatic arthritis (JPsA) are limited. Our study assessed adiposity in children with JPsA in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry. METHODS: Patients with JPsA in the CARRA registry were divided into nonoverweight and overweight groups using recommendations from the US Centers for Disease Control, and differences in demographic and clinical characteristics between groups at baseline and after 1-year followup were assessed using chi-square test, Fisher's exact test, T test, or Mann-Whitney U test, as appropriate...
December 15, 2017: Journal of Rheumatology
Lelly Oboh, Catherine Leon, Sulman Qadir, Felicity Smith, Sally-Anne Francis
Background Older people confined to their own homes due to frailty, multiple longterm conditions and/or complex needs, are known to be at risk of medicines-related problems. Whilst a health and social care team approach to supporting these patients is advocated, there is limited evidence regarding how pharmacists can best contribute. Objective To describe a new specialist pharmacy service (called the integrated care clinical pharmacist) in terms of how it works, what it achieves and its policy implications...
February 2018: International Journal of Clinical Pharmacy
A Grieve, D Harrison, C Westgarth-Taylor, J Loveland
BACKGROUND: Choledochal malformation (CM) is a well-described and relatively rare condition. CMs may present on antenatal ultrasound screening, through childhood and into adulthood. The aetiology is not well understood but the association with a pancreaticobiliary malunion predisposes to the development of CMs. OBJECTIVES: To review the experience of CMs in the Department of Paediatric Surgery, University of the Witwatersrand, Johannesburg to improve our patient care for this population...
November 6, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
Karl Schwaiger, Elisabeth Russe, Klemens Heinrich, Florian Ensat, Gernot Steiner, Gottfried Wechselberger, Michaela Hladik
INTRODUCTION: Thighplasty is a common bodycontouring procedure, but also associated with a high complication rate. The purpose of this study was to access the outcome of the medial horizontal thigh lift as it is a common surgical technique regarding thigh deformity correction performed at the authors' department. Surgical keysteps, clinical applications, advantages and disadvantages of the procedure are shown. Postoperative evaluation took place with special focus on individual patient satisfaction...
October 25, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
I R Wilson
Introduction: Chronic pain carries significant impact and is difficult to treat with limited success. Pain management programmes (PMPs) use cognitive behavioural therapy (CBT)-based multidisciplinary rehabilitative approaches to drive functional improvement. Sources of data: A search was conducted using Medline and the Cochrane Library to identify published literature about PMPs or CBT to treat chronic pain. Areas of agreement: PMPs have significant benefit on functioning for some patients but relatively little impact on the pain...
September 13, 2017: British Medical Bulletin
Osnat Nir, Firas Rinawi, Gil Amarilyo, Liora Harel, Raanan Shamir, Amit Assa
OBJECTIVE: The natural history of pediatric inflammatory bowel disease (IBD) patients with joint involvement has not been clearly described. Thus, we aimed to investigate phenotypic features and clinical outcomes of this distinct association. METHODS: The medical records of patients with pediatric IBD diagnosed from 2000 to 2016 were reviewed retrospectively. Main outcome measures included time to first flare, hospitalization, surgery, and biologic therapy. RESULTS: Of 301 patients with Crohn disease (median age 14...
September 1, 2017: Journal of Rheumatology
Narendra Kumar Bagri, Dinesh Raj, Jasmeet Kaur, Harish Punia, Isha Saini, Rakesh Lodha, S K Kabra
Juvenile systemic sclerosis (JSSc) is a rare disorder with paucity of information on its treatment and longterm  outcome. Herein, we are sharing our experience with this rare entity. Case records of children, diagnosed to have systemic sclerosis attending Pediatric Rheumatology Clinic at All India Institute of Medical Sciences, New Delhi from January 1998 to June 2016 were reviewed. The demographic, clinical, laboratory, treatment and outcome details were recorded. Disease outcome was classified arbitrarily as controlled, partly controlled or non-responsive/progressive based on: (A) ability to perform activities of daily life (ADL) and (B) presence or absence of musculoskeletal symptoms, skin changes (ulceration/progressive digital pitting/gangrene), and visceral organ involvement (dyspahgia, cardiopulmonary symptoms)...
October 2017: Rheumatology International
Andreas Wolter, Naja Pluto, Till Scholz, Jens Diedrichson, Andreas Arens-Landwehr, Jutta Liebau
Introduction Reduction mammaplasty in patients with gigantomastia is challenging even to very experienced plastic surgeons. Extremely elongated pedicles impair the vascular supply of the nipple-areola complex. Breast shaping and effective reduction are difficult due to the severely stretched skin envelope. The Ribeiro technique is the standard technique for reduction mammaplasty in our clinic. The aim of this study is to review our approach in patients with gigantomastia in comparison to the current literature...
August 1, 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
Bo Yang, Yuwei Li
PURPOSE: Laparoscopic thermal ablation is a common alternative to surgical resection for treating colorectal liver metastasis, particularly for metastases located in difficult-to-reach regions. This study aimed to compare the short- and longterm outcomes of laparoscopic radiofrequency ablation (LRFA) and laparoscopic microwave ablation (LMWA) used for treating colorectal liver metastasis. METHODS: Data from patients with colorectal liver metastasis who had undergone LRFA or LMWA from January 2010 to January 2016 were examined...
May 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
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