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Longterm Outcome

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https://www.readbyqxmd.com/read/28207948/right-sided-aortic-arch-in-the-age-of-microarray
#1
Edward F O'Mahony, Darren P Hutchinson, George McGillivray, Debbie L Nisbet, Ricardo Palma-Dias
OBJECTIVE: For fetuses with a diagnosis of right aortic arch and normal cardiac anatomy we aimed to establish the frequency of chromosomal anomaly diagnosed with SNP microarray analysis, particularly focusing on microduplications or microdeletions which would have gone undetected by conventional karyotyping and 6 probe fish (13,18,21, X,Y, TUPLE). METHOD: Retrospective study of fetal ultrasounds between 2011 and 2016 in an Australian tertiary referral centre. Outcomes of interest were survival and postnatal surgery for vascular ring...
February 16, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28202738/longterm-outcomes-of-renal-artery-involvement-in-takayasu-arteritis
#2
Seokchan Hong, Byeongzu Ghang, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo
OBJECTIVE: Takayasu arteritis (TA) involving the renal artery can result in hypertension (HTN), renal dysfunction, and premature death. The aim of this study was to investigate the longterm outcomes and factors that predict outcomes in patients with TA with renal artery stenosis. METHODS: The medical records of patients diagnosed with TA between January 1997 and December 2014 were reviewed retrospectively. Renal artery involvement was based on computed tomography and/or angiography findings...
February 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28200088/mri-assessment-and-outcomes-in-patients-receiving-neoadjuvant-chemotherapy-only-for-primary-rectal-cancer-longterm-results-from-the-gemcad-0801-trial
#3
U B Patel, G Brown, I Machado, J Santos-Cores, C Pericay, E Ballesteros, A Salud, M Isabel-Gil, C Montagut, J Maurel, J Ramón-Ayuso, C Fernandez-Martos
No abstract text is available yet for this article.
February 14, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28145054/longterm-adherence-to-apomorphine-infusion-in-patients-with-parkinson-s-disease-a-10-year-observational-study
#4
Thomas Edmund Kimber, Jing Fang, Lynda Jane Huddy, Philip Douglas Thompson
BACKGROUND: Patients with Parkinson's disease (PD) commonly experience motor fluctuations and dyskinesias in response to oral dopaminergic medications. Affected patients may benefit from a device-assisted therapy, such as medication infusion or deep brain stimulation surgery. This is the first Australian study of the long term adherence to apomorphine infusion (AI) in patients with PD. AIM: to assess the adherence to AI in patients with PD in a single centre over a 10 year period and, in patients who discontinued AI, the reasons for discontinuation...
February 1, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28099984/-longterm-results-of-a-screening-procedure-for-adult-cochlear-implant-candidates
#5
Ulrich Hoppe, Thomas Hocke, Anne Hast, Joachim Hornung
This study gives an estimation of the long term outcome of a screening procedure for cochlear implant candidacy in hearing aid users.In a recent retrospective study, hearing aid performance and audiometric measures in 185 subjects (318 ears) were analyzed. In the context of 2 years follow-up, the outcome of the ipsilateral screening procedure was analyzed. For patients who did receive a cochlear implant, their audiometric outcome measures were viewed into relation to their preoperative results.From the 96 ears identified as cochlear implant candidates, 34 were provided with a cochlear implant...
January 18, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28042127/longterm-beneficial-effect-of-canakinumab-in-colchicine-resistant-familial-mediterranean-fever
#6
Katerina Laskari, Panagiota Boura, George N Dalekos, Alexandros Garyfallos, Dimitrios Karokis, Dimitrios Pikazis, Loukas Settas, Grigoris Skarantavos, Elena Tsitsami, Petros P Sfikakis
OBJECTIVE: To assess the efficacy and safety of the interleukin-1β (IL-1β) inhibitor canakinumab in all adolescent and adult patients with familial Mediterranean fever (FMF) identified from the Greek National Registry for off-label drug use between 2010 and 2015. METHODS: In this retrospective longitudinal outcome study, clinical and laboratory data were collected from 14 patients (7 men) aged median 38.5 years (range 13-70), with median disease duration of 14 years, and active FMF despite colchicine (n = 9) or both colchicine and anakinra (n = 5)...
January 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28042125/lupus-myocarditis-initial-presentation-and-longterm-outcomes-in-a-multicentric-series-of-29-patients
#7
Guillemette Thomas, Fleur Cohen Aubart, Laurent Chiche, Julien Haroche, Miguel Hié, Baptiste Hervier, Nathalie Costedoat-Chalumeau, Karine Mazodier, Mikael Ebbo, Philippe Cluzel, Nadège Cordel, David Ribes, Jean Chastre, Nicolas Schleinitz, Véronique Veit, Jean-Charles Piette, Jean-Robert Harlé, Alain Combes, Zahir Amoura
OBJECTIVE: Cardiac involvement during systemic lupus erythematosus (SLE) may include the pericardium, myocardium, valvular tissue, and coronary arteries. The aim of this study was to describe the clinical, biological, and radiological presentation of lupus myocarditis (LM) as well as the treatment response and longterm outcomes. METHODS: We conducted a multicentric retrospective study of LM from January 2000 to May 2014. RESULTS: Twenty-nine patients (3 men and 26 women) fulfilled the inclusion criteria (median age at the diagnosis of SLE: 30 yrs, range 16-57)...
January 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/27969812/tct-454-does-metallic-stent-design-influence-acute-and-longterm-clinical-outcome-in-second-generation-everolimus-eluting-stents-results-of-a-single-center-2-phase-all-comer-stent-registry
#8
Suzanne Fateh-Moghadam, Tobias Schlegel, Martin Steeg, Antonios Kilias, Wolfgang Bocksch
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27909083/continual-maintenance-of-remission-defined-by-the-acr-eular-criteria-in-daily-practice-leads-to-better-functional-outcomes-in-patients-with-rheumatoid-arthritis
#9
Kumi Shidara, Ayako Nakajima, Eisuke Inoue, Daisuke Hoshi, Naoki Sugimoto, Yohei Seto, Eiichi Tanaka, Shigeki Momohara, Atsuo Taniguchi, Hisashi Yamanaka
OBJECTIVE: To evaluate longterm functional outcomes in rheumatoid arthritis (RA) based on the number of times that the American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) or the 28-joint Disease Activity Score (DAS28) remission criteria were fulfilled. METHODS: Patients with RA who participated in all 6 data collections in an observational cohort from 2008 to 2010 and who fulfilled the DAS28 remission criteria at baseline were studied...
December 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27881011/adjuvant-chemotherapy-with-bevacizumab-i-p-can-prolong-survival-time-of-patients-with-advanced-ovarian-cancer-after-cytoreduction
#10
F DU, P Li, J Chen, Z Gong, C Chi, B Hu, H Chu
Objective To assess whether adjuvant chemotherapy with bevacizumab intraperitoneal (i.p.) is better than adjuvant chemotherapy with bevacizumab intravenous (i.v.) or adjuvant chemotherapy only for patients with advanced ovarian cancer after cytoreduction. Selected patients with advanced ovarian cancer after cytoreduction were divided into three groups depend on their will: adjuvant chemotherapy only; adjuvant chemotherapy combined with bevacizumab intravenous (i.v.); adjuvant chemotherapy combined with bevacizumab intraperitoneal (i...
November 24, 2016: Neoplasma
https://www.readbyqxmd.com/read/27856353/urolithiasis-in-renal-transplant-donors-and-recipients-an-update
#11
REVIEW
Ahmed M Harraz, Ahmed I Kamal, Ahmed A Shokeir
Urolithiasis in the context of renal transplant is a quite rare event that requires keeping a higher index of suspicion and vigilance. Donors with incidentally discovered asymptomatic renal stones "donor gifted lithiasis" are potentially considered for donation should they are not recurrent stone formers and in the absence of active biochemical disorders. Stone clearance from the donors can be done before donation using shock wave lithotripsy and/or flexible ureteroscopy. Ex vivo ureteroscopy at time of transplant is equally feasible and safe...
December 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27830578/adjuvant-steroid-treatment-following-kasai-portoenterostomy-and-clinical-outcomes-of-biliary-atresia-patients-an-updated-meta-analysis
#12
Min-Zhong Zhang, Peng-Cheng Xun, Ka He, Wei Cai
BACKGROUND: It is controversial whether adjuvant steroid treatment should be given to biliary atresia (BA) patients following a Kasai portoenterostomy (KPE). This study aimed to quantitatively and systematically evaluate the effect of adjuvant steroid therapy post-KPE in relation to major clinical outcomes of BA patients. METHODS: We systematically reviewed the literature in PubMed, Embase, the Cochrane Library, China Knowledge Resource Integrated Database, Wanfang Database, Scholarly and Academic Information Navigator and manually searched for relevant papers published before August, 2015...
February 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/27803490/impact-of-homocysteine-level-on-long-term-cardiovascular-outcomes-in-patients-after-coronary-artery-stenting
#13
Jih-Kai Yeh, Chun-Chi Chen, Ming-Jer Hsieh, Ming-Lung Tsai, Chia-Hung Yang, Dong-Yi Chen, Shang-Hung Chang, Chao-Yung Wang, Cheng-Hung Lee, I-Chang Hsieh
AIM: The prognostic value of homocysteine (HCY) in patients with coronary artery diseases (CAD) is still controversial. The objective of this study was to investigate whether elevated HCY level at admission predict long-term outcomes in patients after percutaneous coronary interventions (PCI) with coronary artery stenting. METHODS: From the institutional registry of Cardiovascular Atherosclerosis and Percutaneous TrAnsluminal INterventions (CAPTAIN), we enrolled a total of 1,307 patients with documented CAD undergone PCI with bare metal stents from July 2003 to December 2014...
November 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27744392/effects-of-longterm-treatment-with-bosentan-and-iloprost-on-nailfold-absolute-capillary-number-fingertip-blood-perfusion-and-clinical-status-in-systemic-sclerosis
#14
Amelia Chiara Trombetta, Carmen Pizzorni, Barbara Ruaro, Sabrina Paolino, Alberto Sulli, Vanessa Smith, Maurizio Cutolo
OBJECTIVE: To quantify in patients with systemic sclerosis (SSc) the absolute nailfold capillary number/mm (the absolute number of capillaries, observable in the first row, in 1 mm per field) and fingertip blood perfusion (FBP) during longterm therapy with the endothelin receptor antagonist bosentan (BOSE) and the synthetic analog of prostacyclin PGI2 iloprost (ILO) by multiple diagnostic tools. Observed values were correlated with clinical outcomes. METHODS: Thirty patients with SSc already receiving intravenous ILO (80 μg/day) for 5 continuous days (every 3 mos) were recruited in the clinic...
October 1, 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/27739103/impact-of-competing-risk-of-mortality-on-association-of-weight-loss-with-risk-of-central-body-fractures-in-older-men-a-prospective-cohort-study
#15
Kristine E Ensrud, Stephanie L Harrison, Jane A Cauley, Lisa Langsetmo, John T Schousboe, Deborah M Kado, Margaret L Gourlay, Jennifer G Lyons, Lisa Fredman, Nicolas Napoli, Carolyn J Crandall, Cora E Lewis, Eric S Orwoll, Marcia L Stefanick, Peggy M Cawthon
To determine the association of weight loss with risk of clinical fractures at the hip, spine and pelvis (central body fractures [CBF]) in older men with and without accounting for the competing risk of mortality, we used data from 4,523 men (mean age 77.5 years). Weight change between baseline and follow-up (mean 4.5 years between examinations) was categorized as moderate loss (loss ≥10%), mild loss (loss 5% to <10%), stable (<5% change) or gain (gain ≥5%). Participants were contacted every 4 months after the follow-up examination to ascertain vital status (deaths verified by death certificates) and ask about fractures (confirmed by radiographic reports)...
October 14, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/27705975/frequency-and-determinants-of-adherence-to-oral-anticoagulants-in-stroke-patients-with-atrial-fibrillation-in-clinical-practice
#16
Alexandros A Polymeris, Christopher Traenka, Lisa Hert, David J Seiffge, Nils Peters, Gian Marco De Marchis, Leo H Bonati, Philippe A Lyrer, Stefan T Engelter
BACKGROUND: Vitamin K antagonists (VKAs) and non-VKA oral anticoagulants (NOACs) are beneficial in patients with stroke and atrial fibrillation (AF). However, little is known about frequency and determinants of adherence to NOACs/VKAs in clinical practice. METHODS: This is a single-center explorative study from the Novel Oral Anticoagulants in Stroke Patients (NOACISP)-LONGTERM registry. We included consecutive AF-stroke patients treated with NOACs/VKAs and followed up for 3-24 months...
2016: European Neurology
https://www.readbyqxmd.com/read/27704472/-revival-after-ebola-multidisciplinary-assessment-at-1-year-prospect-and-follow-up-study-of-surviving-patients-from-ebola-in-guinea-postebogui-cohort
#17
P Msellati, A Touré, M S Sow, K Cécé, B Taverne, A Desclaux, M Barry, J-F Etard, E Delaporte
Ebola virus disease (EVD) epidemic that spread in West Africa from the end of 2013 to early 2016 has reached more people than all past epidemics. Beyond care management of acute phase ill patients and measures for the control of the epidemic, the outcome of Ebola survivors became an important question as their number increased and raised new issues. A multidisciplinary prospective cohort of survivors in Guinea has been launched by IRD UMI 233 and Donka National Hospital, Conakry, Guinea, to assess the long-term clinical, psychological, sociological, immunological, and viral outcomes potentially related to EVD...
October 2016: Bulletin de la Société de Pathologie Exotique
https://www.readbyqxmd.com/read/27676978/modified-brain-activations-in-the-non-damaged-hemisphere-during-movements-of-the-supposed-to-be-healthy-upper-limb
#18
Liesjet Van Dokkum, Emmanuelle Le Bars, Denis Mottet, Alain Bonafe, Nicolas Menjot de Champfleur, Isabelle Laffont
OBJECTIVE: After stroke, the less affected upper-limb shows slight but substantial and longterm motor deficits [1]. Kinematically, this is reflected by an increased segmentation of movements. Here, we aim to define how these changes in behavior are accompanied by changes in brain activation. MATERIAL/PATIENTS AND METHODS: Twenty-one sub-acute post-stroke patients with a first-ever unilateral ischemic stroke of the middle cerebral artery participated in this study twice: within the first 6 weeks post-stroke and after 6 weeks of rehabilitation...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27593593/longterm-survival-outcomes-of-patients-undergoing-treatment-with-radiofrequency-ablation-for-hepatocellular-carcinoma-and-metastatic-colorectal-cancer-liver-tumors
#19
Iswanto Sucandy, Susannah Cheek, Benjamin J Golas, Allan Tsung, David A Geller, James W Marsh
BACKGROUND: We aim to investigate long-term survival outcomes in patients undergoing radiofrequency ablation (RFA), based on our longitudinal 5 and 10 year follow-up data. METHODS: All patients who underwent RFA for hepatocellular carcinoma (HCC) and colorectal liver metastasis (CLM) between 1999 and 2010. RESULTS: 320 patients were included with oncologic diagnoses of HCC in 122 (38.1%) and CLM in 198 (61.9%). The majority of patients had a single tumor ablation (71% RFA 1 lesion)...
September 2016: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/27576011/why-are-there-so-many-mastectomies-in-the-united-states
#20
Anita Mamtani, Monica Morrow
Breast-conserving therapy (BCT) and mastectomy result in equivalent long-term survival. Locoregional recurrence rates after BCT have decreased over time and are now similar to those after mastectomy. Contralateral breast cancer rates are declining as well owing to the widespread use of adjuvant systemic therapy. Despite these improved outcomes, increasing rates of bilateral mastectomy for unilateral cancer have been observed in the United States. Medical indications for mastectomy are well defined and present in a minority of patients, and women at increased risk for contralateral cancer are a small proportion of the breast cancer population...
January 14, 2017: Annual Review of Medicine
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