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https://www.readbyqxmd.com/read/28811093/risk-factors-for-infective-endocarditis-in-children-with-congenital-heart-diseases-a-nationwide-population-based-case-control-study
#1
Li-Chuan Sun, Chih-Cheng Lai, Cheng-Yi Wang, Ya-Hui Wang, Jen-Yu Wang, Yo-Ling Hsu, Yin-Lan Hu, En-Ting Wu, Ming-Tai Lin, Leticia B Sy, Likwang Chen
BACKGROUND: Infective endocarditis (IE) is uncommon in childhood. Its associated epidemiological characteristics in patients with congenital heart disease (CHD) remain unclear. METHODS: The study population included children born in Taiwan during the years 1997 to 2005 who were diagnosed as having CHD before 3years of age. All children were followed up until the end year of 2010, the diagnosis of infective endocarditis, or death. The demographic characteristics of patients with and without IE, the invasive procedures performed during 6months before the index date, the prophylactic antibiotics related to dental procedures, and in-hospital mortality were collected...
August 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28804238/percutaneous-closure-of-the-aorto-ostial-origin-of-a-coronary-artery-saphenous-bypass-graft-with-a-large-pseudoaneurysm-using-the-amplatzer-muscular-ventricular-septal-defect-occluder
#2
Nicolas W Shammas, Majid Z Chammas, Jon Robken, Dale Geiss
We report the case of a 76-year-old male patient with a history of coronary artery bypass graft surgery presented with a large pseudoaneurysm emerging from a previously occluded saphenous bypass graft (SVG). A largely contained hematoma is seen in the mediastinum on computed tomography angiography (CTA) of the chest. Flow was seen from the ascending aorta into the pseudoaneurysm through the aorto-ostial opening of the bypass graft. Closure of the aorto-ostial origin of the graft was performed using the AMPLATZER muscular ventricular septal defect (VSD) occluder (St Jude's Medical, St...
September 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28780843/-initial-study-of-transthoracic-echocardiography-guided-three-dimensional-printing-on-the-application-of-assessment-of-structural-heart-disease
#3
Y B Zhu, J S Liu, L Q Wang, X Guan, Y J Luo, J Geng, Q G Geng, Y J Lin, L X Zhang, X X Li, Y P Lu
Objective: To investigate the feasibility and diagnostic value of preoperative transthoracic echocardiography guided three dimensional printing model (TTE Guided 3DPM) on the assessment of structural heart disease (SHD). Methods: From February 2016 to October 2016, 44 patients underwent cardiac surgery in Tianjin Chest Hospital, forty-four patients were assessed preoperatively using TTE Guided 3DPM, including 25 males and 19 females, aged 3-75 years, with an average of (44±22) years. compared to conventional three dimensional transthoracic echocardiography (3D-TTE), and took direct intraoperative findings as "Golden Standard" simultaneously...
August 1, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28758112/parental-genetic-variants-mthfr-677c-t-and-mtrr-66a-g-associated-differently-with-fetal-congenital-heart-defect
#4
Qian-Nan Guo, Hong-Dan Wang, Li-Zhen Tie, Tao Li, Hai Xiao, Jian-Gang Long, Shi-Xiu Liao
BACKGROUND: Congenital heart defect (CHD) is one of the most common birth defects in the world. The methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) genes are two of the most important candidate genes for fetal CHD. However, the correlations between the two genes and fetal CHD were inconsistent in various reports. Therefore, this study is aimed to evaluate the parental effects of the two genes on fetal CHD via three genetic polymorphisms, MTHFR 677C>T (rs1801133), MTHFR 1298 A>C (rs1801131), and MTRR 66A>G (rs1801394)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28752252/prenatal-diagnosis-of-pulmonary-atresia-with-ventricular-septal-defect
#5
Shui-Hua Yang, Peng-Hui Luo, Xiao-Xian Tian, Xin-Yan Li, Xue-Qin Li, Zuo-Jian Yang, Sheng-Li Li
Pulmonary atresia with ventricular septal defect (PA-VSD) is a rare complex congenital heart defect. Major artery-pulmonary collateral arteries (MAPCAs) are characteristic of PA-VSD. Prenatal diagnosis can be achieved in most cases of PA-VSD with recent advances in echocardiography. However, it is extremely rare that all MAPCAs can be observed on the echocardiograph. Here, we report a case of prenatally diagnosed type C PA-VSD in which all the MAPCAs could be seen on the echocardiograph, with the diagnosis supported by autopsy evidence...
July 27, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28738517/modelling-long-term-impacts-of-changes-in-climate-nitrogen-deposition-and-ozone-exposure-on-carbon-sequestration-of-european-forest-ecosystems
#6
Wim de Vries, Maximilian Posch, David Simpson, Gert Jan Reinds
We modelled the effects of past and expected future changes in climate (temperature, precipitation), CO2 concentration, nitrogen deposition (N) and ozone (O3) exposure (phytotoxic ozone dose, POD) on carbon (C) sequestration by European forest ecosystems for the period 1900-2050. Tree C sequestration was assessed by using empirical response functions, while soil C sequestration was simulated with the process-based model VSD, combined with the RothC model. We evaluated two empirical growth responses to N deposition (linear and non-linear) and two O3 exposure relationships (linear function with total biomass or net annual increment)...
July 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28730300/health-related-quality-of-life-in-paediatric-patients-with-congenital-heart-defects-association-with-the-type-of-heart-defect-and-the-surgical-technique
#7
A Heusch, H J Kahl, K O Hensel, G Calaminus
The aim of the study was to investigate the impact of a number of surgical interventions for a various congenital cardiac defects (CHDs) on self-reported HRQoL. METHODS: Patients who had received corrective surgery of several congenital heart defects (surgical VSD closure, Fallot, TGA after atrial or arterial switch or Fontan-type circulation for univentricular AV-connection) were interviewed in the office of their home peadiatric cardiologist. HRQoL in children along 7 dimensions was assessed using a standardised questionnaire (PEDQoL); information on the medical case history of each respondent was also collected...
July 20, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28728260/-clinical-analysis-of-pacing-therapy-and-treatment-of-complications-during-follow-up-in-children
#8
P J Zhao, Y W Chen, F Li, Y Li, J P Yang, J J Wu
Objective: To analyze characteristics of permanent pacemaker implantation in children as well as treatment and prognosis of complications. Method: Clinical data of children who underwent endocardial or epicardial permanent pacemaker implantation between April 2000 and June 2016 in Shanghai Xinhua Hospital and Shanghai Children's Medical Center were analyzed retrospectively. These patients were discharged 5 days after implantation. Electrocardiogram, chest X ray, echocardiography and pacemaker programming were performed during follow-up...
July 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/28720590/mechanisms-of-noncovalent-%C3%AE-subunit-regulation-of-nav-channel-gating
#9
Wandi Zhu, Taylor L Voelker, Zoltan Varga, Angela R Schubert, Jeanne M Nerbonne, Jonathan R Silva
Voltage-gated Na(+) (NaV) channels comprise a macromolecular complex whose components tailor channel function. Key components are the non-covalently bound β1 and β3 subunits that regulate channel gating, expression, and pharmacology. Here, we probe the molecular basis of this regulation by applying voltage clamp fluorometry to measure how the β subunits affect the conformational dynamics of the cardiac NaV channel (NaV1.5) voltage-sensing domains (VSDs). The pore-forming NaV1.5 α subunit contains four domains (DI-DIV), each with a VSD...
July 18, 2017: Journal of General Physiology
https://www.readbyqxmd.com/read/28711966/modified-single-patch-technique-versus-two-patch-technique-for-the-repair-of-complete-atrioventricular-septal-defect-a-meta-analysis
#10
Dongxu Li, Qiang Fan, Tomoyuki Iwase, Yasutaka Hirata, Qi An
Technical selection for surgical repair of complete atrioventricular septal defect (CAVSD) still remains controversial. This meta-analysis aimed to compare the modified single-patch (MP) technique with the two-patch (TP) technique for patients with CAVSD. Relevant studies comparing the MP technique with the TP technique were identified through a literature search using MEDLINE, EMBASE, Google Scholar, Cochrane Library, and the China National Knowledge Infrastructure databases. The variables were ventricular septal defect (VSD) size, cardiopulmonary bypass (CBP) time, aortic cross-clamp (ACC) time, intensive care unit stay, hospital stay, and other outcomes involving mortality, left ventricular outflow tract obstruction, atrioventricular valve regurgitation, residual septal shunt, atrioventricular block, and reoperation...
July 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28711965/efficacy-of-an-extracellular-matrix-in-systemic-loading-conditions-in-congenital-heart-surgery
#11
Adeel Ashfaq, Amit Iyengar, Oh Jin Kwon, Mohammad S Soroya, Son Nguyen, Ryan Ou, Brian Reemtsen
Extracellular matrices (ECM) are commonly used to repair congenital heart defects; however, there is a lack of literature pertaining to outcomes with ECM use in high-pressure conditions. Between 2011 and 2014, a total of 202 patients underwent congenital heart disease repair using the ECM placed in a systemic pressure condition. The operative sites included: defects in the ventricular septum, mitral valve, aortic valve, ascending aorta, and aortic arch. Patients were followed and evaluated for mortality and reoperations due to loss of ECM integrity...
July 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28709847/topographical-projections-from-the-nucleus-basalis-magnocellularis-meynert-to-the-frontal-cortex-a-voltage-sensitive-dye-imaging-study-in-rats
#12
Kazuaki Nagasaka, Yumiko Watanabe, Ichiro Takashima
BACKGROUND: The nucleus basalis magnocellularis/Meynert (NBM) has been explored as a new target for deep brain stimulation for neurological disorders. Although anatomical studies suggest the existence of cholinergic topographical projections of the NBM, it is still unknown whether NBM subregions differentially activate the frontal cortex. OBJECTIVE: To investigate the topography between the NBM and frontal cortex. METHODS: Electrical stimulation was applied to the anterior and posterior sites of the NBM in rats, and the evoked frontal activity was investigated using voltage-sensitive dye (VSD) imaging...
July 3, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28709589/initial-experience-of-transcatheter-closure-of-subarterial-vsd-with-the-amplatzer-duct-occluder
#13
Tsung-Cheng Shyu, Ming-Chih Lin, Yeak-Wun Quek, Sheng-Je Lin, Hean-Pat Saw, Sheng-Ling Jan, Yun-Ching Fu
BACKGROUND: The traditional treatment of subarterial ventricular septal defect (VSD) is open heart surgery. This study aimed to evaluate the feasibility, safety and outcome of transcatheter closure with the Amplatzer duct occluder (ADO). METHODS: Between March 2012 and June 2015, a total of 16 patients (8 male and 8 female) with subarterial VSD who underwent transcatheter closure with the ADO were enrolled retrospectively. Their age ranged from 3.0 to 65.6 years, with the median of 35...
July 11, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28707408/complete-heart-block-following-transcatheter-closure-of-perimembranous-vsd-using-amplatzer-duct-occluder-ii
#14
Sanjiban Ghosh, Anuradha Sridhar, Muthukumaran Sivaprakasam
Long term follow up studies have shown that transcatheter closure of perimembranous Ventricular Septal Defect (PmVSD) can be done safely and successfully. One of the most serious complications of VSD device closure is complete atrioventricular block which has been reported in 3-18% is various studies following VSD device closure. Amplatzar Duct Occluder II (ADO-II) device is now commonly being used for closure of small to moderate sized PmVSD. Complete heart block has not been reported with ADO-II device. We are reporting 2 cases of complete heart block following transcatheter closure of PmVSD using ADO-II device where sinus rhythm was established following early surgical removal of the device...
July 14, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28702146/are-polymorphisms-in-mtrr-a66g-and-mthfr-c677t-genes-associated-with-congenital-heart-diseases-in-iranian-population
#15
Noormohammad Noori, Ebrahim Miri-Moghaddam, Asieh Dejkam, Yasman Garmie, Ali Bazi
BACKGROUND: The 5, 10-methyleneterahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) are two essential enzymes involved in folate metabolism. The relationship between genetic polymorphisms and congenital heart defects (CHDs) is inconsistent. Our aim was to investigate the association between two well-known polymorphisms of MTHFR and MTRR genes, C677T and A66G, respectively, and CHDs in Iranian patients. METHODS: We enrolled 74 patients with ventricular septal defect (VSD) and 79 with tetralogy of fallot (TOF) along with 147 healthy controls...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28692975/a-novel-method-of-minimizing-view-synthesis-distortion-based-on-its-non-monotonicity-in-3d-video
#16
Meng Yang, Nanning Zheng, Ce Zhu, Fei Wang
In depth-based 3D video, the view synthesis distortion (VSD) is generally measured by modeling the effect of texture and depth errors separately. With such a development, it has been referred that the VSD changes monotonically w.r.t. to both the texture and depth distortions. In this paper, we find the VSD not always change monotonically with them by both theoretical analysis and experimental test, when the effect of the texture and depth errors are considered together. Specifically, 1) we prove that the VSD is non-monotonic with the texture distortion...
July 5, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28681451/factors-associated-with-aortic-root-dilatation-after-surgically-repaired-ventricular-septal-defect
#17
Chihiro Saito, Noritoshi Fukushima, Keiko Fukushima, Goki Matsumura, Kyomi Ashihara, Nobuhisa Hagiwara
BACKGROUND: Aortic root dilatation (ARD) in congenital heart disease is related to aortic aneurysm, rupture, and dissection. This study aimed to investigate the factors associated with ARD in patients with surgically repaired ventricular septal defect (VSD). METHODS: This cross-sectional study included 152 patients with surgically repaired VSD. Two definitions of ARD were used: (1) observed Valsalva diameter to body surface area (BSA) ratio >2.1 cm/m(2) and (2) absolute value of Valsalva diameter ≥4...
July 6, 2017: Echocardiography
https://www.readbyqxmd.com/read/28679899/intelligent-phonocardiography-for-screening-ventricular-septal-defect-using-time-growing-neural-network
#18
Arash Gharehbaghi, Amir A Sepehri, Maria Lindén, Ankica Babic
This paper presents results of a study on the applicability of the intelligent phonocardiography in discriminating between Ventricular Spetal Defect (VSD) and regurgitation of the atrioventricular valves. An original machine learning method, based on the Time Growing Neural Network (TGNN), is employed for classifying the phonocardiographic recordings collected from the pediatric referrals to a children hospital. 90 individuals, 30 VSD, 30 with the valvular regurgitation, and 30 healthy subjects, participated in the study after obtaining the informed consents...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28672762/critical-congenital-heart-disease-screening-with-a-pulse-oximetry-in-neonates
#19
Şahin Hamilçıkan, Emrah Can
OBJECTIVE: To compare the results of pulse oximetry screening for critical congenital heart disease (CCHD) in newborn infants performed at <24 h and >24 h following. METHOD: Measurements were taken for each group at <24 h and >24 h following birth. Echocardiography was performed if the SpO2 readings remained abnormal results. RESULTS: A total of 4518 newborns were included in this prospective descriptive study. Of these, 2484 (60...
June 27, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28648426/percutaneous-closure-of-symptomatic-large-tricuspid-paravalvular-regurgitation-using-two-muscular-vsd-occluders
#20
Aritra Mukherji, Rajaram Anantharaman, Raghavan Subramanyan
Paravalvular leaks are common following valve replacement surgery. Majority are benign and do not require any active intervention. However, occasionally severe paravalvular regurgitation can produce heart failure and/or hemolysis, needing closure of the defect. It is more commonly associated with aortic and mitral prosthesis, symptomatic tricuspid paravalvular regurgitation being a rare entity. In this report we present the successful percutaneous transcatheter closure of a large paravalvular tricuspid regurgitation in a 59-year old lady with history of multiple previous operations...
May 2017: Indian Heart Journal
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