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https://www.readbyqxmd.com/read/27904843/cardiac-surgery-in-africa-a-thirty-five-year-experience-on-open-heart-surgery-in-cote-d-ivoire
#1
Koffi Herve Yangni-Angate, Christophe Meneas, Florent Diby, Manga Diomande, Anicet Adoubi, Yves Tanauh
BACKGROUND: Few centers for open heart surgery (OHS) are in Sub-Saharan Africa. Lack of OHS results is also noted. By reporting our African experience on OHS, the aim of this study was to fill the gap. METHODS: It is a retrospective study on 2,612 patients who were subject to an OHS between 1978 and 2013. Data were collected from demographical, clinical, investigative studies, surgical and outcomes parameters. RESULTS: There were 1,475 cases of rheumatic heart diseases (RHD), 126 endomyocardial fibrosis (EMF), 741 congenital heart diseases (CHDs) and 270 various affections...
October 2016: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/27896608/developing-tools-to-counteract-and-prevent-suicide-bomber-incidents-a-case-study-in-value-sensitive-design
#2
Lambèr Royakkers, Marc Steen
Developers and designers make all sorts of moral decisions throughout an innovation project. In this article, we describe how teams of developers and designers engaged with ethics in the early phases of innovation based on case studies in the SUBCOP project (SUBCOP stands for 'SUicide Bomber COunteraction and Prevention'). For that purpose, Value Sensitive Design (VSD) will be used as a reference. Specifically, we focus on the following two research questions: How can researchers/developers learn about users' perspectives and values during the innovation process? and How can researchers/developers take into account these values, and related design criteria, in their decision-making during the innovation process? Based on a case study of several innovation processes in this project, we conclude the researchers/developers involved are able to do something similar to VSD (without them knowing about VSD or calling it 'VSD'), supported by relatively simple exercises in the project, e...
November 28, 2016: Science and Engineering Ethics
https://www.readbyqxmd.com/read/27891775/surveillance-of-ventricular-septal-defects-in-delaware
#3
Amy Acheson, Anika Vaidy, Kathleen Stomieroski, Dana R Thompson, Kristin M Maiden, Deborah B Ehrenthal, Samir Yezdani, Abdul Majeed Bhat, Robert Locke, Louis E Bartoshesky
BACKGROUND: The prevalence of ventricular septal defects (VSDs), a birth defect in which there is an opening in the wall that separates the left and right ventricles of the heart, seemed to be substantially higher in Delaware compared with the National Birth Defects Prevention Network (NBDPN). The Delaware Birth Defects Registry (BDR) noted their high prevalence of VSDs in comparison with other states. METHODS: A subset of children with a VSD born in 2007 through 2010 was identified from the complete reportable statewide defect list that the BDR creates each year...
November 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27878850/analysis-of-morphological-changes-after-facial-massage-by-a-novel-approach-using-three-dimensional-computed-tomography
#4
H Nishimura, I Okuda, N Kunizawa, T Inoue, Y Nakajima, S Amano
BACKGROUND/PURPOSE: Photograph-based visual scoring has been used for evaluation of facial morphological changes. Here, we describe a three-dimensional computed tomography (3D-CT) method for objective analysis of facial and intra-facial (subcutaneous) changes. The effects of facial massage were examined using both methods. METHODS: Subjects were 12 healthy female volunteers without facial scars or deformation (age 30-54 years, mean 39.4 years). Photograph-based scoring of massage-induced morphological changes was done at the nasolabial folds, upper, lower and lateral cheeks and lower eyelids...
November 22, 2016: Skin Research and Technology
https://www.readbyqxmd.com/read/27876309/vertical-breast-measurement-in-east-asian-women-a-guide-for-mastopexy-and-reduction-to-form-nonptotic-breasts-in-unilateral-prosthetic-breast-reconstruction
#5
Takashi Fujiwara, Kenji Yano, Yoshio Tanji, Masaya Nomura
BACKGROUND: Following unilateral breast cancer surgery, mastopexy and reduction of the unaffected breast are often performed to obtain symmetrical breasts. The use of implants in breast reconstruction results in a nonptotic breast. To achieve symmetry following the procedure, the unaffected side should be nonptotic too. However, no study has yet reported any indices for the design of mastopexy and reduction in this direction. We present a new method of preoperative design that uses vertical breast measurements to form nonptotic breasts according to individual breast shapes...
October 26, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/27876287/mid-term-outcomes-of-common-congenital-heart-defects-corrected-through-a-right-subaxillary-thoracotomy
#6
Guoying An, Hongyu Zhang, Shanguang Zheng, Weixin Wang, Liming Ma
OBJECTIVE: To evaluate the mid-term outcomes of the correction of various congenital heart defects through a right subaxillary thoracotomy. METHODS: Between June 2004 and April 2014, all eligible patients were those with a common congenital heart defect corrected via an approach through a right subaxillary thoracotomy. There were 836 patients (male 417, female 419; median age, 3.5 years; median weight 13.6kg) with ventricular septal defect (VSD) closure (523 patients), atrial septal defect (ASD) closure (235 patients), partial atrioventricular canal (PAVC) correction (55 patients), mild tetralogy of Fallot (TOF) (23 patients)...
February 17, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27872996/surgical-repair-of-ventricular-septal-defect-contemporary-results-and-risk-factors-for-a-complicated-course
#7
Maartje Schipper, Martijn G Slieker, Paul H Schoof, Johannes M P J Breur
Surgical closure of the ventricular septal defect is the most commonly performed procedure in pediatric cardiac surgery. There are conflicting data on weight at operation as risk factor for a complicated course. We performed a retrospective evaluation of mortality and morbidity in all patients undergoing surgical ventricular septal defect closure at our institution between 2004 and 2012 to identify risk factor for a complicated course. Multivariate logistic regression modeling was performed to identify risk factors for a complicated course...
November 21, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27871331/association-of-dars-gene-polymorphisms-with-the-risk-of-isolated-ventricular-septal-defects-in-the-chinese-han-population
#8
Yu Feng, Runsen Chen, Xuming Mo
BACKGROUND: Ventricular septal defects (VSD) are the most common subtype of congenital heart defects (CHD) and are estimated to account for 20 to 30% of all cases of CHD. The etiology of isolated VSD remains poorly understood. Eight core aminoacyl-tRNA synthetases (ARSs) (EPRS, MARS, QARS, RARS, IARS, LARS, KARS, and DARS) combine with three nonenzymatic components to form a complex known as the multisynthetase complex (MSC). Four single nucleotide polymorphisms (SNPs) in EPRS have been reported to be associated with risks of CHD in Chinese populations...
November 21, 2016: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/27867454/predictors-for-the-outcome-of-aortic-regurgitation-after-cardiac-surgery-in-patients-with-ventricular-septal-defect-and-aortic-cusp-prolapse-in-saudi-patients
#9
Hiba Gaafar Salih, Sameh R Ismail, Mohamed S Kabbani, Riyadh M Abu-Sulaiman
BACKGROUND AND AIM: Aortic valve (AV) prolapse and subsequent aortic regurgitation (AR) are two complications of ventricular septal defects (VSD) that are located close to or in direct contact with the AV. This finding is one of the indications for surgical VSD closure even in the absence of symptoms to protect the AV integrity. The goal of our study was to assess the outcome and to identify the predictors for improvement or progression of AR after surgical repair. MATERIALS AND METHODS: A retrospective study of all children with VSD and AV prolapse who underwent cardiac surgery at King Abdulaziz Cardiac Centre in Riyadh between July 1999 and August 2013...
July 2016: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/27866021/early-pulmonary-arterial-hypertension-immediately-after-closure-of-a-ventricular-or-complete-atrioventricular-septal-defect-beyond-6months-of-age
#10
P Bambul Heck, A Eicken, J Kasnar-Samprec, P Ewert, A Hager
BACKGROUND: Pulmonary arterial hypertension (PAH) is virtually absent after closure of ventricular septal defect (VSD) in the first six months of life. However the prevalence of PAH in patients, who underwent VSD closure later, is not clear. The aim of this study was to analyse the prevalence of PAH after a successful VSD closure after the age of 6months and whether there are risk factors for developing PAH. METHODS: Echocardiographic and right heart catheter data of patients with VSD or complete atrioventricular septal defect, who underwent VSD closure after the age of 6months in our institution between 01/2005 and 06/2014, were retrospectively analyzed...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27865179/right-coronary-artery-disappeared-after-giant-right-coronary-artery-fistula-draining-into-left-ventricle-occluded-by-vsd-occluder-what-we-can-learn-from-this
#11
EDITORIAL
Xuechao Tang, Feiyu Wang, Yuan Bai, Xiaohua You, Xudong Xu, Yongwen Qin
No abstract text is available yet for this article.
October 29, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27861393/vacuum-sealing-drainage-therapy-in-the-presence-of-an-external-fixation-device-a-case-report
#12
Dahui Sun, Weina Ju, Tiejun Wang, Tiecheng Yu, Baochang Qi
RATIONALE: Vacuum sealing drainage (VSD) is widely utilized for treating traumatic wounds. PATIENT CONCERNS: It is particularly difficult and time consuming to use in combination with an external fixator. DIAGNOSES: This is because the hardware or pins used for fixation interfere with maintaining a seal, resulting in poor adhesion and subsequent air leakage. INTERVENTIONS: To resolve this problem, we have devised a new method for sealing the wound dressing, while maintaining the required vacuum...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27853286/disulfide-mapping-the-voltage-sensing-mechanism-of-a-voltage-dependent-potassium-channel
#13
Tomohiro Nozaki, Shin-Ichiro Ozawa, Hitomi Harada, Tomomi Kimura, Masanori Osawa, Ichio Shimada
Voltage-dependent potassium (Kv) channels allow for the selective permeability of potassium ions in a membrane potential dependent manner, playing crucial roles in neurotransmission and muscle contraction. Kv channel is a tetramer, in which each subunit possesses a voltage-sensing domain (VSD) and a pore domain (PD). Although several lines of evidence indicated that membrane depolarization is sensed as the movement of helix S4 of the VSD, the detailed voltage-sensing mechanism remained elusive, due to the difficulty of structural analyses at resting potential...
November 17, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27847970/interventional-vsd-closure-with-the-nit-occlud-%C3%A2-l%C3%A3%C2%AA-vsd-coil-in-110-patients-early-and-midterm-results-of-the-eureveco-registry
#14
Nikolaus A Haas, Laura Kock, Harald Bertram, Regina Boekenkamp, Daniel De Wolf, Igor Ditkivskyy, Matthias W Freund, Marc Gewillig, Christoph M Happel, Ulrike Herberg, Edvard Karthasyan, Rainer Kozlik-Feldmann, Oliver Kretschmar, Yulia Kuzmenko, Ornella Milanesi, Goetz Mueller, Giacomo Pongiglione, Stephan Schubert, Gleb Tarusinov, Christoph Kampmann
In August 2010, the Nit-Occlud(®) Lê (EUREVECO) became available for transcatheter coil occlusion of ventricular septal defects (VSDs). Retrospective European Registry for VSD Closure using the Nit-Occlud(®) Lê-VSD-Coil; analysis of the feasibility, results, safety and follow-up of VSD-closure over a 3-year period in 18 European centers. In 102 of 111 patients (female 66), successful VSD closure was performed (mean age 8.2 years, mean weight 28.82 kg), 81 perimembranous VSDs (48 with aneurysm), 30 muscular VSDs, mean procedure time was 121...
November 15, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27837306/circulating-microrna-as-a-novel-biomarker-for-pulmonary-arterial-hypertension-due-to-congenital-heart-disease
#15
Weidan Chen, Shoujun Li
Circulating microRNAs (miRNAs) have recently been indicated as practical and promising biomarkers for various diseases. However, circulating miRNAs have not been found to be biomarkers for pulmonary arterial hypertension (PAH) due to congenital heart disease. PAH is defined by a mean pulmonary arterial pressure (mPAP) >25 mmHg at rest. Blood samples and lung tissues were collected from patients with severe PAH due to ventricular septal defect (VSD) (PAH group, mPAP >45 mmHg, n=14) and patients with VSD but non-PAH (control group, mPAP <25 mmHg, n=16)...
November 11, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27830886/anomalous-left-brachiocephalic-vein-important-vascular-anomaly-concomitant-with-congenital-anomalies-and-heart-diseases
#16
Shahram Kahkouee, Makan Sadr, Elham Pedarzadeh, Sara Fardin, Ali Borhani, Saeid Gholami, Ghazaleh Amjad
BACKGROUND: Anomalous left brachiocephalic vein (ALBCV) is a rare and less known systemic venous anomaly. Infrequently, this vein takes an abnormal course and passes to the right behind or beneath the aortic arch to create the superior vena cava (SVC). Its incidence was reported much higher in patients with congenital heart disease (CHD) especially in conotruncal and aortic arch anomalies. It could be misdiagnosed with normal or abnormal mediastinal structures. It also could make complication during surgeries or invasive strategies...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27829962/successful-closure-of-a-ventricular-septal-defect-using-a-novel-non-prosthesis-touching-technique-following-mechanical-aortic-valve-replacement
#17
Xinghua Gu, Hourong Sun, Lei Zhang, Changjing Qi, Kejie Cai, Xiquan Zhang
Percutaneous intervention is preferred over reoperation for the treatment of iatrogenic membranous ventricular septal defects (VSDs). During the standard percutaneous procedure, an arterio-venous loop is used for occluder deployment, entailing the risk of device impingement on the prosthetic aortic valve, which may cause serious complications or even death. In this report, we describe a novel non-prosthesis touching procedure for the closure of a VSD in a patient with prior aortic valve replacement. The unique feature of this technique is the use of an apex-venous loop for occluder deployment, which prevents the device impingement on the prosthetic valve, thus avoiding difficulties, lengthy operation and serious complications associated with the standard procedure...
December 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27829956/bi-luminal-mitral-valve-incidence-clinical-features-associated-anomaly-and-echocardiographic-evaluation
#18
Santosh Kumar Sinha, Vikas Mishra, Karandeep Singh, Mohammad Asif, Mohit Sachan, Ashutosh Kumar, Mukesh Jitendra Jha, Dibbendhu Khanra, Avinash Kumar Singh, Shravan Singh, Mahamdula Razi, Ramesh Thakur, Umeshwar Pandey, Chandra Mohan Varma
OBJECTIVE: The aim of the study was to know the incidence, clinical features, associated anomaly and echocardiographic evaluation of bi-luminal mitral valve (also known as double orifice mitral valve or DOMV) in patients with suspected mitral valve disease, continous murmur or left-to-right shunt. METHODS: Twenty-eight patients with DOMV were diagnosed by transthoracic echocardiography (TTE) in a retrospective review of 52,256 echocardiographic studies in 45,898 patients performed between 2000 and 2015...
December 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27826129/genotypic-and-phenotypic-predictors-of-complete-heart-block-and-recovery-of-conduction-following-surgical-repair-of-congenital-heart-disease
#19
Laura Murray, Andrew H Smith, English C Flack, Kim Crum, Jill Owen, Prince J Kannankeril
BACKGROUND: Complete heart block (CHB) is a major complication after congenital heart surgery. We hypothesized that genetic and clinical factors are associated with the development of postoperative CHB and recovery of atrioventricular (AV) conduction. OBJECTIVE: To identify predictors of CHB and recovery following congenital heart surgery. METHODS: Patients undergoing congenital heart surgery at our institution from September 2007 through June 2015 were prospectively enrolled in a parent study of postoperative arrhythmias...
November 5, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27816473/characterization-of-soluble-n-ethylmaleimide-sensitive-factor-attachment-protein-receptor-gene-stx18-variations-for-possible-roles-in-congenital-heart-diseases
#20
Xia Li, Shuai Shi, Fei-Feng Li, Rui Cheng, Ying Han, Li-Wei Diao, Qiong Zhang, Ji-Xin Zhi, Shu-Lin Liu
Congenital heart disease (CHD) is among the most prevalent and complex congenital anatomic malformations in newborns. Interactions of cardiac progenitor with a broad range of cellular regulatory factors play key roles in the formation of mammalian heart and pathogenesis of CHD. STX18 is a soluble N-ethylmaleimide-sensitive factor attachment protein receptor, which is involved in numeral cellular activities such as organelle assembly and the cell cycle. The aim of this work was to find evidence on whether STX18 variations might be associated with CHD in Chinese Han populations...
November 2, 2016: Gene
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